Professor Kristopher Kilian

Professor Kristopher Kilian

Professor
Science
School of Chemistry

Prof Kris Kilian is Director of the Laboratory for Advanced Biomaterials & Matrix Engineering (LAB&ME) with a joint position across the School of Chemistry and the School of Materials Science & Engineering in the Faculty of Science, UNSW Sydney. He is co-Director of the Australian Centre for NanoMedicine (ACN) and a member of the Adult Cancer Program in the Prince of Wales Clinical School. He worked for Merck Research Labs in the Methods Development group from 2000-2004 before travelling to Sydney, Australia to do his PhD at the University of New South Wales. In 2007, Kris joined the laboratory of Milan Mrksich at the University of Chicago as a NIH postdoctoral fellow to investigate new methods for directing the differentiation of stem cells. He was Assistant Professor (2011-2017) and Associate Professor (2017-2018) at the University of Illinois at Urbana-Champaign in the Department of Materials Science and Engineering, and the Department of Bioengineering, before returning to UNSW in 2018 as a Scientia Fellow between the School of Chemistry and the School of Materials Science and Engineering. Kris is a recipient of the Cornforth Medal from the Royal Australian Chemical Institute (2008), the NIH Ruth L. Kirchstein National Research Service Award (2008), a Kavli Fellow of the 19th German-American Frontiers of Science (2014), the National Science Foundation’s CAREER award (2015), a Young Innovator of Cellular and Molecular Bioengineering (2017), the Australian Research Council Future Fellowship (2018), the Dean's Award for Research Excellence (2020) and a Eureka Prize finalist for Innovative Use of Technology (2023). His research interests include the design and development of model extracellular matrices and dynamic hydrogels for cell and tissue engineering, and fundamental studies in cell plasticity.

For more information please visit the Laboratory for Advanced Biomaterials and Matrix Engineering

Phone
+61-2-9385 6998
Location
740 Hilmer Building (E10)
  • Book Chapters | 2023
    LaPointe V; Kilian KA, 2023, 'Cellular signaling', in Tissue Engineering, Elsevier, pp. 109 - 135, http://dx.doi.org/10.1016/B978-0-12-824459-3.00004-4
    Book Chapters | 2022
    Romanazzo S; Kilian KA, 2022, 'Geometric Cues for Directing Cell Fate', in Material-based Mechanobiology, The Royal Society of Chemistry, pp. 85 - 109, http://dx.doi.org/10.1039/9781839165375-00085
    Book Chapters | 2021
    Romanazzo S; Kilian KA; Roohani I, 2021, 'iPSC bioprinting for musculoskeletal tissue', in iPSCs in Tissue Engineering, pp. 237 - 270, http://dx.doi.org/10.1016/B978-0-12-823809-7.00008-6
    Book Chapters | 2015
    Kilian KA, 2015, 'Biomaterials: Incorporating ECM-Derived Molecular Features into Biomaterials', in Mimicking the Extracellular Matrix, The Royal Society of Chemistry, pp. 161 - 194, http://dx.doi.org/10.1039/9781839168956-00161
  • Journal articles | 2024
    Ajam A; Huang Y; Islam MS; Kilian KA; Kruzic JJ, 2024, 'Mechanical and biological behavior of double network hydrogels reinforced with alginate versus gellan gum', Journal of the Mechanical Behavior of Biomedical Materials, 157, http://dx.doi.org/10.1016/j.jmbbm.2024.106642
    Journal articles | 2024
    Doshi RB; Vakil D; Molley TG; Islam MS; Kilian KA; Cunningham C; Sidhu KS, 2024, 'Mesenchymal stem cell-secretome laden photopolymerizable hydrogels for wound healing', Journal of Biomedical Materials Research - Part A, 112, pp. 1484 - 1493, http://dx.doi.org/10.1002/jbm.a.37697
    Journal articles | 2024
    Ireland J; Kilian KA, 2024, 'The importance of matrix in cardiomyogenesis: Defined substrates for maturation and chamber specificity', Matrix Biology Plus, 24, http://dx.doi.org/10.1016/j.mbplus.2024.100160
    Journal articles | 2024
    Jalandhra GK; Hung TT; Kilian KA, 2024, 'Laponite Nanoclay-Loaded Microgel Suspensions as Supportive Matrices for Osteogenesis', Advanced NanoBiomed Research, 4, http://dx.doi.org/10.1002/anbr.202400024
    Journal articles | 2024
    Jalandhra GK; Kilian KA, 2024, 'Biofabrication approaches to fabricating gradients and interfaces in osteochondral tissue engineering', Current Opinion in Biomedical Engineering, 31, http://dx.doi.org/10.1016/j.cobme.2024.100544
    Journal articles | 2024
    Johnson KK; Koshy P; Kopecky C; Devadason M; Biazik J; Zheng X; Jiang Y; Wang X; Liu Y; Holst J; Yang JL; Kilian KA; Sorrell CC, 2024, 'ROS-mediated anticancer effects of EGFR-targeted nanoceria', Journal of Biomedical Materials Research - Part A, 112, pp. 754 - 769, http://dx.doi.org/10.1002/jbm.a.37656
    Journal articles | 2024
    Karimi F; Farbehi N; Ziaee F; Lau K; Monfared M; Kordanovski M; Joukhdar H; Molly TG; Nordon R; Kilian KA; Stenzel MH; Lim KS; Rnjak-Kovacina J, 2024, 'Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202313354
    Journal articles | 2024
    Karimi F; Farbehi N; Ziaee F; Lau K; Monfared M; Kordanovski M; Joukhdar H; Molly TG; Nordon R; Kilian KA; Stenzel MH; Lim KS; Rnjak‐Kovacina J, 2024, 'Photocrosslinked Silk Fibroin Microgel Scaffolds for Biomedical Applications (Adv. Funct. Mater. 29/2024)', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202470158
    Journal articles | 2024
    Soliman BG; Nguyen AK; Gooding JJ; Kilian KA, 2024, 'Advancing Synthetic Hydrogels through Nature-Inspired Materials Chemistry', Advanced Materials, 36, pp. e2404235, http://dx.doi.org/10.1002/adma.202404235
    Journal articles | 2024
    Tran HA; Maraldo A; Ho TTP; Thai MT; van Hilst Q; Joukhdar H; Kordanovski M; Sahoo JK; Hartsuk O; Santos M; Wise SG; Kaplan DL; Do TN; Kilian KA; Lim KS; Rnjak-Kovacina J, 2024, 'Probing the Interplay of Protein Self-Assembly and Covalent Bond Formation in Photo-Crosslinked Silk Fibroin Hydrogels', Small, http://dx.doi.org/10.1002/smll.202407923
    Journal articles | 2023
    Islam MS; Molley TG; Hung TT; Sathish CI; Putra VDL; Jalandhra GK; Ireland J; Li Y; Yi J; Kruzic JJ; Kilian KA, 2023, 'Magnetic Nanofibrous Hydrogels for Dynamic Control of Stem Cell Differentiation', ACS Applied Materials and Interfaces, 15, pp. 50663 - 50678, http://dx.doi.org/10.1021/acsami.3c07021
    Journal articles | 2023
    Jalandhra GK; Molley TG; Hung TT; Roohani I; Kilian KA, 2023, 'In situ formation of osteochondral interfaces through “bone-ink” printing in tailored microgel suspensions', Acta Biomaterialia, 156, pp. 75 - 87, http://dx.doi.org/10.1016/j.actbio.2022.08.052
    Journal articles | 2023
    K. Johnson K; Kopecky C; Koshy P; Liu Y; Devadason M; Holst J; A. Kilian K; C. Sorrell C, 2023, 'Theranostic Activity of Ceria-Based Nanoparticles toward Parental and Metastatic Melanoma: 2D vs 3D Models', ACS Biomaterials Science and Engineering, 9, pp. 1053 - 1065, http://dx.doi.org/10.1021/acsbiomaterials.2c01258
    Journal articles | 2023
    Kilian K; Fischbach C; Fong ELS, 2023, 'Engineered Biomaterials for Developing the Next Generation of In Vitro Tumor Models', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202300411
    Journal articles | 2023
    Liu Y; Nemec S; Kopecky C; Stenzel MH; Kilian KA, 2023, 'Hydrogel Microtumor Arrays to Evaluate Nanotherapeutics', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202201696
    Journal articles | 2023
    Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120
    Journal articles | 2023
    Moore MJ; Lam YT; Santos M; Tan RP; Yang N; Hung J; Li Z; Kilian KA; Rnjak-Kovacina J; Pitts JB; Menzel H; Wise SG, 2023, 'Evaluation of the Immune Response to Chitosan-graft-poly(caprolactone) Biopolymer Scaffolds', ACS Biomaterials Science and Engineering, 9, pp. 3320 - 3334, http://dx.doi.org/10.1021/acsbiomaterials.3c00553
    Journal articles | 2023
    Nguyen AK; Molley TG; Kardia E; Ganda S; Chakraborty S; Wong SL; Ruan J; Yee BE; Mata J; Vijayan A; Kumar N; Tilley RD; Waters SA; Kilian KA, 2023, 'Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41907-1
    Journal articles | 2023
    Putra VDL; Kilian KA; Knothe Tate ML, 2023, 'Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment', Communications Biology, 6, http://dx.doi.org/10.1038/s42003-022-04320-w
    Journal articles | 2023
    Srivastava P; Romanazzo S; Kopecky C; Nemec S; Ireland J; Molley TG; Lin K; Jayathilaka PB; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, 2023, 'Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202203614
    Journal articles | 2023
    Suwannakot P; Nemec S; Peres NG; Du EY; Kilian KA; Gaus K; Kavallaris M; Gooding JJ, 2023, 'Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands', ACS Biomaterials Science and Engineering, 9, pp. 1362 - 1376, http://dx.doi.org/10.1021/acsbiomaterials.2c01252
    Journal articles | 2023
    Huang Y; Jayathilaka PB; Islam MS; Tanaka CB; Silberstein MN; Kilian KA; Kruzic JJ, 2023, 'Corrigendum to ‘Structural aspects controlling the mechanical and biological properties of tough, double network hydrogels’ [Acta Biomaterialia 138 (2022) 301–312, (S1742706121007133), (10.1016/j.actbio.2021.10.044)]', Acta Biomaterialia, http://dx.doi.org/10.1016/j.actbio.2023.02.007
    Journal articles | 2022
    Huang Y; Jayathilaka PB; Islam MS; Tanaka CB; Silberstein MN; Kilian KA; Kruzic JJ; Baptiston Tanaka C, 2022, 'Structural aspects controlling the mechanical and biological properties of tough, double network hydrogels', Acta Biomaterialia, 138, pp. 301 - 312, http://dx.doi.org/10.1016/j.actbio.2021.10.044
    Journal articles | 2022
    Jalandhra G; Romanazzo S; Nemec S; Roohani I; Kilian KA, 2022, 'Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs', Journal of Visualized Experiments, http://dx.doi.org/10.3791/63943-v
    Journal articles | 2022
    Jalandhra G; Romanazzo S; Nemec S; Roohani I; Kilian KA, 2022, 'Ceramic Omnidirectional Bioprinting in Cell-laden Suspensions for the Generation of Bone Analogs', Journal of Visualized Experiments, 2022, http://dx.doi.org/10.3791/63943
    Journal articles | 2022
    Khosravanihaghighi A; Koshy P; Yasir M; Romanazzo S; Lovric V; Kilian KA; Willcox MD; Walsh WR; Sorrell CC, 2022, 'Production of Antibacterial Activity and Bone Cell Proliferation by Surface Engineering of Ga- or Mn-Doped Ceria-Coated Biomedical Titanium Alloy', Advanced Engineering Materials, 24, http://dx.doi.org/10.1002/adem.202200077
    Journal articles | 2022
    Molley TG; Hung TT; Kilian KA, 2022, 'Cell-Laden Gradient Microgel Suspensions for Spatial Control of Differentiation During Biofabrication', Advanced Healthcare Materials, 11, http://dx.doi.org/10.1002/adhm.202201122
    Journal articles | 2022
    Nemec S; Ganda S; Al Taief K; Kopecky C; Kuchel R; Lebhar H; Marquis CP; Thordarson P; Kilian KA, 2022, 'A Tunable Tumor Microenvironment through Recombinant Bacterial Collagen-Hyaluronic Acid Hydrogels', ACS Applied Bio Materials, 5, pp. 4581 - 4588, http://dx.doi.org/10.1021/acsabm.2c00186
    Journal articles | 2022
    Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347
    Journal articles | 2022
    Zhang C; Yang B; Biazik J; Webster RF; Xie W; Tang J; Allioux F-M; Abbasi R; Mousavi M; Goldys EM; Killian KA; Chandrawati R; Esrafilzadeh D; Kalantar-Zadeh K, 2022, 'Gallium Nanodroplets are Anti-Inflammatory without Interfering with Iron Homeostasis', ACS Nano, http://dx.doi.org/10.1021/acsnano.1c10981
    Journal articles | 2021
    Islam MS; Molley TG; Ireland J; Kruzic JJ; Kilian KA, 2021, 'Magnetic Nanocomposite Hydrogels for Directing Myofibroblast Activity in Adipose-Derived Stem Cells', Advanced NanoBiomed Research, 1, http://dx.doi.org/10.1002/anbr.202000072
    Journal articles | 2021
    Jayathilaka PB; Molley TG; Huang Y; Islam MS; Buche MR; Silberstein MN; Kruzic JJ; Kilian KA, 2021, 'Force-mediated molecule release from double network hydrogels', Chemical Communications, 57, pp. 8484 - 8487, http://dx.doi.org/10.1039/d1cc02726c
    Journal articles | 2021
    Lee J; Abdeen AA; Li Y; Goonetilleke S; Kilian KA, 2021, 'Gradient and Dynamic Hydrogel Materials to Probe Dynamics in Cancer Stem Cell Phenotypes', ACS Applied Bio Materials, 4, pp. 711 - 720, http://dx.doi.org/10.1021/acsabm.0c01263
    Journal articles | 2021
    Ma L; Geng J; Kolossov VL; Han Z; Pei Y; Lim SJ; Kilian KA; Smith AM, 2021, 'Antibody self-assembly maximizes cytoplasmic immunostaining accuracy of compact quantum dots', Chemistry of Materials, 33, pp. 4877 - 4889, http://dx.doi.org/10.1021/acs.chemmater.1c00164
    Journal articles | 2021
    Molley TG; Jalandhra GK; Nemec SR; Tiffany AS; Patkunarajah A; Poole K; Harley BAC; Hung TT; Kilian KA, 2021, 'Heterotypic tumor models through freeform printing into photostabilized granular microgels', Biomaterials Science, 9, pp. 4496 - 4509, http://dx.doi.org/10.1039/d1bm00574j
    Journal articles | 2021
    Nemec S; Kilian KA, 2021, 'Materials control of the epigenetics underlying cell plasticity', Nature Reviews Materials, 6, pp. 69 - 83, http://dx.doi.org/10.1038/s41578-020-00238-z
    Journal articles | 2021
    Nemec S; Lam J; Zhong J; Heu C; Timpson P; Li Q; Youkhana J; Sharbeen G; Phillips PA; Kilian KA, 2021, 'Cancer‐Associated Fibroblasts: Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells (Adv. Biology 6/2021)', Advanced Biology, 5, http://dx.doi.org/10.1002/adbi.202170064
    Journal articles | 2021
    Nemec S; Lam J; Zhong J; Heu C; Timpson P; Li Q; Youkhana J; Sharbeen G; Phillips PA; Kilian KA, 2021, 'Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells', Advanced Biology, 5, pp. e2000525, http://dx.doi.org/10.1002/adbi.202000525
    Journal articles | 2021
    Romanazzo S; Molley TG; Nemec S; Lin K; Sheikh R; Gooding JJ; Wan B; Li Q; Kilian KA; Roohani I, 2021, 'Synthetic Bone-Like Structures Through Omnidirectional Ceramic Bioprinting in Cell Suspensions', Advanced Functional Materials, 31, pp. 2008216, http://dx.doi.org/10.1002/adfm.202008216
    Journal articles | 2021
    Seidlits SK; Kilian KA, 2021, 'Biomaterials for Personalized Disease Models', Acta Biomaterialia, 132, pp. 1 - 3, http://dx.doi.org/10.1016/j.actbio.2021.08.034
    Journal articles | 2021
    Thavapalachandran S; Le TYL; Romanazzo S; Rashid FN; Ogawa M; Kilian KA; Brown P; Pouliopoulos J; Barry AM; Fahmy P; Kelly K; Kizana E; Chong JJH, 2021, 'Pluripotent stem cell-derived mesenchymal stromal cells improve cardiac function and vascularity after myocardial infarction', Cytotherapy, 23, pp. 1074 - 1084, http://dx.doi.org/10.1016/j.jcyt.2021.07.016
    Journal articles | 2021
    Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Srivastava P; Potas JR; Hung T; Power C; Hardy P; Ma DD; Kilian KA; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE; Subramanian S, 2021, 'Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine', Science Advances, 7, pp. eabd1929, http://dx.doi.org/10.1126/sciadv.abd1929
    Journal articles | 2020
    Lee J; Molley TG; Seward CH; Abdeen AA; Zhang H; Wang X; Gandhi H; Yang J-L; Gaus K; Kilian KA, 2020, 'Geometric regulation of histone state directs melanoma reprogramming', Communications Biology, pp. 872226 - 872226, http://dx.doi.org/10.1101/872226
    Journal articles | 2020
    Lee J; Molley TG; Seward CH; Abdeen AA; Zhang H; Wang X; Gandhi H; Yang JL; Gaus K; Kilian KA, 2020, 'Geometric regulation of histone state directs melanoma reprogramming', Communications Biology, 3, pp. 341, http://dx.doi.org/10.1038/s42003-020-1067-1
    Journal articles | 2020
    Li Y; Fanous MJ; Kilian KA; Popescu G, 2020, 'Author Correction: Quantitative phase imaging reveals matrix stiffness-dependent growth and migration of cancer cells (Scientific Reports, (2019), 9, 1, (248), 10.1038/s41598-018-36551-5)', Scientific Reports, 10, pp. 19025, http://dx.doi.org/10.1038/s41598-020-75941-6
    Journal articles | 2020
    Molley TG; Jalandhra GK; Nemec SR; Tiffany AS; Harley BAC; Hung T-T; Kilian KA, 2020, 'Freeform printing of heterotypic tumor models within cell-laden microgel matrices', , pp. 2020.08.30.274654, http://dx.doi.org/10.1101/2020.08.30.274654
    Journal articles | 2020
    Molley TG; Wang X; Hung T; Jayathilaka PB; Yang J; Kilian KA, 2020, 'Geometrically Structured Microtumors: Geometrically Structured Microtumors in 3D Hydrogel Matrices (Adv. Biosys. 5/2020)', Advanced Biology, 4, http://dx.doi.org/10.1002/adbi.202070053
    Journal articles | 2020
    Molley TG; Wang X; Hung TT; Jayathilaka PB; Yang JL; Kilian KA, 2020, 'Geometrically Structured Microtumors in 3D Hydrogel Matrices', Advanced Biosystems, 4, pp. e2000056, http://dx.doi.org/10.1002/adbi.202000056
    Journal articles | 2020
    Nguyen AK; Kilian KA, 2020, 'Physicochemical Tools for Visualizing and Quantifying Cell-Generated Forces', ACS Chemical Biology, 15, pp. 1731 - 1746, http://dx.doi.org/10.1021/acschembio.0c00304
    Journal articles | 2020
    Pei Y; Molley TG; Kilian KA, 2020, 'Enzyme Responsive Inverse Opal Hydrogels', Macromolecular Rapid Communications, 41, pp. e1900555, http://dx.doi.org/10.1002/marc.201900555
    Journal articles | 2020
    Romanazzo S; Lin K; Srivastava P; Kilian KA, 2020, 'Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming', Advanced Drug Delivery Reviews, 161-162, pp. 124 - 144, http://dx.doi.org/10.1016/j.addr.2020.08.007
    Journal articles | 2020
    Ruprai H; Shanu A; Mawad D; Hook JM; Kilian K; George L; Wuhrer R; Houang J; Myers S; Lauto A, 2020, 'Porous chitosan adhesives with L-DOPA for enhanced photochemical tissue bonding', Acta Biomaterialia, 101, pp. 314 - 326, http://dx.doi.org/10.1016/j.actbio.2019.10.046
    Journal articles | 2019
    Bandara SR; Molley TG; Kim H; Bharath PA; Kilian KA; Leal C, 2019, 'The structural fate of lipid nanoparticles in the extracellular matrix', Materials Horizons, 00, pp. 125 - 134, http://dx.doi.org/10.1039/c9mh00835g
    Journal articles | 2019
    Fanous MJ; Li Y; Kandel ME; Abdeen AA; Kilian KA; Popescu G, 2019, 'Effects of substrate patterning on cellular spheroid growth and dynamics measured by gradient light interference microscopy (GLIM)', Journal of Biophotonics, 12, pp. e201900178, http://dx.doi.org/10.1002/jbio.201900178
    Journal articles | 2019
    Le P; Lim SJ; Baculis BC; Chung HJ; Kilian KA; Smith AM, 2019, 'Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions', Nature Communications, 10, pp. 909, http://dx.doi.org/10.1038/s41467-019-08754-5
    Journal articles | 2019
    Li Y; Fanous MJ; Kilian KA; Popescu G, 2019, 'Quantitative phase imaging reveals matrix stiffness-dependent growth and migration of cancer cells', Scientific Reports, 9, pp. 248, http://dx.doi.org/10.1038/s41598-018-36551-5
    Journal articles | 2019
    Ruprai H; Romanazzo S; Ireland J; Kilian K; Mawad D; George L; Wuhrer R; Houang J; Ta D; Myers S; Lauto A, 2019, 'Porous Chitosan Films Support Stem Cells and Facilitate Sutureless Tissue Repair', ACS Applied Materials and Interfaces, 11, pp. 32613 - 32622, http://dx.doi.org/10.1021/acsami.9b09123
    Journal articles | 2019
    Sridharan Weaver S; Li Y; Foucard L; Majeed H; Bhaduri B; Levine AJ; Kilian KA; Popescu G, 2019, 'Simultaneous cell traction and growth measurements using light', Journal of Biophotonics, 12, pp. e201800182, http://dx.doi.org/10.1002/jbio.201800182
    Journal articles | 2019
    Srivastava P; Kilian KA, 2019, 'Micro-Engineered Models of Development Using Induced Pluripotent Stem Cells', Frontiers in Bioengineering and Biotechnology, 7, pp. 357, http://dx.doi.org/10.3389/fbioe.2019.00357
    Journal articles | 2018
    Anorma C; Hedhli J; Bearrood TE; Pino NW; Gardner SH; Inaba H; Zhang P; Li Y; Feng D; Dibrell SE; Kilian KA; Dobrucki LW; Fan TM; Chan J, 2018, 'Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1', ACS Central Science, 4, pp. 1045 - 1055, http://dx.doi.org/10.1021/acscentsci.8b00313
    Journal articles | 2018
    Pei Y; Shahoei SH; Li Y; Reece PJ; Nelson ER; Gooding JJ; Kilian KA, 2018, 'Porous Silicon: Vertical Integration of Cell‐Laden Hydrogels with Bioinspired Photonic Crystal Membranes (Adv. Mater. Interfaces 23/2018)', Advanced Materials Interfaces, 5, http://dx.doi.org/10.1002/admi.201870115
    Journal articles | 2018
    Pei Y; Shahoei SH; Li Y; Reece PJ; Nelson ER; Gooding JJ; Kilian KA, 2018, 'Vertical Integration of Cell-Laden Hydrogels with Bioinspired Photonic Crystal Membranes', Advanced Materials Interfaces, 5, http://dx.doi.org/10.1002/admi.201801233
    Journal articles | 2017
    Abdeen AA; Lee J; Li Y; Kilian KA, 2017, 'Cytoskeletal Priming of Mesenchymal Stem Cells to a Medicinal Phenotype', Regenerative Engineering and Translational Medicine, 3, pp. 5 - 14, http://dx.doi.org/10.1007/s40883-016-0021-8
    Journal articles | 2017
    Hedhli J; Konopka CJ; Schuh S; Bouvin H; Cole JA; Huntsman HD; Kilian KA; Dobrucki IT; Boppart MD; Dobrucki LW, 2017, 'Multimodal assessment of mesenchymal stem cell therapy for diabetic vascular complications', Theranostics, 7, pp. 3876 - 3888, http://dx.doi.org/10.7150/thno.19547
    Journal articles | 2017
    Lee J; Abdeen AA; Hedhli J; Wycislo KL; Dobrucki IT; Fan TM; Dobrucki LW; Kilian KA, 2017, 'Melanoma topology reveals a stem-like phenotype that promotes angiogenesis', Science Advances, 3, pp. e1701350, http://dx.doi.org/10.1126/sciadv.1701350
    Journal articles | 2017
    Li Y; Tang CB; Kilian KA, 2017, 'Matrix Mechanics Influence Fibroblast–Myofibroblast Transition by Directing the Localization of Histone Deacetylase 4', Cellular and Molecular Bioengineering, 10, pp. 405 - 415, http://dx.doi.org/10.1007/s12195-017-0493-8
    Journal articles | 2017
    McDougle DR; Watson JE; Abdeen AA; Adili R; Caputo MP; Krapf JE; Johnson RW; Kilian KA; Holinstat M; Das A, 2017, 'Anti-inflammatory ω-3 endocannabinoid epoxides', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. E6034 - E6043, http://dx.doi.org/10.1073/pnas.1610325114
    Journal articles | 2017
    Zhang D; Lee J; Kilian KA, 2017, 'Synthetic Biomaterials to Rival Nature's Complexity—a Path Forward with Combinatorics, High-Throughput Discovery, and High-Content Analysis', Advanced Healthcare Materials, 6, pp. 1700535, http://dx.doi.org/10.1002/adhm.201700535
    Journal articles | 2017
    Zhang D; Lee J; Sun MB; Pei Y; Chu J; Gillette MU; Fan TM; Kilian KA, 2017, 'Combinatorial Discovery of Defined Substrates That Promote a Stem Cell State in Malignant Melanoma', ACS Central Science, 3, pp. 381 - 393, http://dx.doi.org/10.1021/acscentsci.6b00329
    Journal articles | 2016
    Abdeen AA; Lee J; Bharadwaj NA; Ewoldt RH; Kilian KA, 2016, 'Temporal Modulation of Stem Cell Activity Using Magnetoactive Hydrogels', Advanced Healthcare Materials, 5, pp. 2536 - 2544, http://dx.doi.org/10.1002/adhm.201600349
    Journal articles | 2016
    Abdeen AA; Lee J; Kilian KA, 2016, 'Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes', Experimental Biology and Medicine, 241, pp. 930 - 938, http://dx.doi.org/10.1177/1535370216644532
    Journal articles | 2016
    Huang TH; Pei Y; Zhang D; Li Y; Kilian KA, 2016, 'Patterned porous silicon photonic crystals with modular surface chemistry for spatial control of neural stem cell differentiation', Nanoscale, 8, pp. 10891 - 10895, http://dx.doi.org/10.1039/c5nr08327c
    Journal articles | 2016
    Kilian KA; Moghe PV, 2016, 'High throughput strategies for the design, discovery, and analysis of biomaterials', Acta Biomaterialia, 34, pp. v - vi, http://dx.doi.org/10.1016/j.actbio.2016.03.019
    Journal articles | 2016
    Lee J; Abdeen AA; Tang X; Saif TA; Kilian KA, 2016, 'Matrix directed adipogenesis and neurogenesis of mesenchymal stem cells derived from adipose tissue and bone marrow', Acta Biomaterialia, 42, pp. 46 - 55, http://dx.doi.org/10.1016/j.actbio.2016.06.037
    Journal articles | 2016
    Lee J; Abdeen AA; Wycislo KL; Fan TM; Kilian KA, 2016, 'Interfacial geometry dictates cancer cell tumorigenicity', Nature Materials, 15, pp. 856 - 862, http://dx.doi.org/10.1038/nmat4610
    Journal articles | 2016
    Lee J; Silberstein MN; Abdeen AA; Kim SY; Kilian KA, 2016, 'Mechanochemical functionalization of disulfide linked hydrogels', Materials Horizons, 3, pp. 447 - 451, http://dx.doi.org/10.1039/c6mh00091f
    Journal articles | 2016
    Liu Y; Norton JJS; Qazi R; Zou Z; Ammann KR; Liu H; Yan L; Tran PL; Jang KI; Lee JW; Zhang D; Kilian KA; Jung SH; Bretl T; Xiao J; Slepian MJ; Huang Y; Jeong JW; Rogers JA, 2016, 'Epidermal mechano-acoustic sensing electronics for cardiovascular diagnostics and human-machine interfaces', Science Advances, 2, pp. e1601185, http://dx.doi.org/10.1126/sciadv.1601185
    Journal articles | 2016
    Zhang D; Sun MB; Lee J; Abdeen AA; Kilian KA, 2016, 'Cell shape and the presentation of adhesion ligands guide smooth muscle myogenesis', Journal of Biomedical Materials Research - Part A, 104, pp. 1212 - 1220, http://dx.doi.org/10.1002/jbm.a.35661
    Journal articles | 2015
    Abdeen AA; Lee J; Mo SH; Kilian KA, 2015, 'Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis', Journal of Materials Chemistry B, 3, pp. 7896 - 7898, http://dx.doi.org/10.1039/c5tb01294e
    Journal articles | 2015
    Grolman JM; Zhang D; Smith AM; Moore JS; Kilian KA, 2015, 'Rapid 3D Extrusion of Synthetic Tumor Microenvironments', Advanced Materials, 27, pp. 5512 - 5517, http://dx.doi.org/10.1002/adma.201501729
    Journal articles | 2015
    Grolman JM; Zhang D; Smith AM; Moore JS; Kilian KA, 2015, 'Tumor Microenvironments: Rapid 3D Extrusion of Synthetic Tumor Microenvironments (Adv. Mater. 37/2015)', Advanced Materials, 27, pp. 5445 - 5445, http://dx.doi.org/10.1002/adma.201570242
    Journal articles | 2015
    Lee J; Abdeen AA; Kim AS; Kilian KA, 2015, 'Influence of Biophysical Parameters on Maintaining the Mesenchymal Stem Cell Phenotype', ACS Biomaterials Science and Engineering, 1, pp. 218 - 226, http://dx.doi.org/10.1021/ab500003s
    Journal articles | 2015
    Lee J; Abdeen AA; Tang X; Saif TA; Kilian KA, 2015, 'Geometric guidance of integrin mediated traction stress during stem cell differentiation', Biomaterials, 69, pp. 174 - 183, http://dx.doi.org/10.1016/j.biomaterials.2015.08.005
    Journal articles | 2015
    Li Y; Kilian KA, 2015, 'Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices', Advanced Healthcare Materials, 4, pp. 2780 - 2796, http://dx.doi.org/10.1002/adhm.201500427
    Journal articles | 2014
    Abdeen AA; Weiss JB; Lee J; Kilian KA, 2014, 'Matrix composition and mechanics direct proangiogenic signaling from mesenchymal stem cells', Tissue Engineering - Part A, 20, pp. 2737 - 2745, http://dx.doi.org/10.1089/ten.tea.2013.0661
    Journal articles | 2014
    Lee J; Abdeen AA; Huang TH; Kilian KA, 2014, 'Controlling cell geometry on substrates of variable stiffness can tune the degree of osteogenesis in human mesenchymal stem cells', Journal of the Mechanical Behavior of Biomedical Materials, 38, pp. 209 - 218, http://dx.doi.org/10.1016/j.jmbbm.2014.01.009
    Journal articles | 2014
    Lee J; Abdeen AA; Kilian KA, 2014, 'Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment', Scientific Reports, 4, pp. 5188, http://dx.doi.org/10.1038/srep05188
    Journal articles | 2014
    Zhang D; Kilian KA, 2014, 'Peptide microarrays for the discovery of bioactive surfaces that guide cellular processes: A single step azide-alkyne "click" chemistry approach', Journal of Materials Chemistry B, 2, pp. 4280 - 4288, http://dx.doi.org/10.1039/c4tb00375f
    Journal articles | 2013
    Lee J; Abdeen AA; Zhang D; Kilian KA, 2013, 'Directing stem cell fate on hydrogel substrates by controlling cell geometry, matrix mechanics and adhesion ligand composition', Biomaterials, 34, pp. 8140 - 8148, http://dx.doi.org/10.1016/j.biomaterials.2013.07.074
    Journal articles | 2013
    Zhang D; Kilian KA, 2013, 'The effect of mesenchymal stem cell shape on the maintenance of multipotency', Biomaterials, 34, pp. 3962 - 3969, http://dx.doi.org/10.1016/j.biomaterials.2013.02.029
    Journal articles | 2012
    Boecking T; Kilian KA; Reece PJ; Gaus K; Gal M; Gooding JJ, 2012, 'Biofunctionalization of free-standing porous silicon films for self-assembly of photonic devices', Soft Matter, 8, pp. 360 - 366, http://dx.doi.org/10.1039/c1sm06651j
    Journal articles | 2012
    Kilian KA; Mrksich M, 2012, 'Directing Stem Cell Fate by Controlling the Affinity and Density of Ligand–Receptor Interactions at the Biomaterials Interface', Angewandte Chemie, 124, pp. 4975 - 4979, http://dx.doi.org/10.1002/ange.201108746
    Journal articles | 2012
    Kilian KA; Mrksich M, 2012, 'Directing stem cell fate by controlling the affinity and density of ligand-receptor interactions at the biomaterials interface', Angewandte Chemie - International Edition, 51, pp. 4891 - 4895, http://dx.doi.org/10.1002/anie.201108746
    Journal articles | 2011
    Guan B; Magenau AI; Kilian KA; Ciampi S; Gaus K; Reece PJ; Gooding JJ, 2011, 'Mesoporous silicon photonic crystal microparticles: Towards single-cell optical biosensors', Faraday Discussions, 149, pp. 301 - 317, http://dx.doi.org/10.1039/c005340f
    Journal articles | 2010
    Boecking T; Kilian KA; Reece PJ; Gaus K; Gal M; Gooding JJ, 2010, 'Substrate independent assembly of optical structures guided by biomolecular interactions', ACS Applied Materials & Interfaces, 2, pp. 3270 - 3275, http://dx.doi.org/10.1021/am1007084
    Journal articles | 2010
    Gurard-Levin ZA; Kilian KA; Kim J; Bähr K; Mrksich M, 2010, 'Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity', ACS Chemical Biology, 5, pp. 863 - 873, http://dx.doi.org/10.1021/cb100088g
    Journal articles | 2010
    Kilian KA; Bugarija B; Lahn BT; Mrksich M, 2010, 'Geometric cues for directing the differentiation of mesenchymal stem cells', Proceedings of the National Academy of Sciences of the United States of America, 107, pp. 4872 - 4877, http://dx.doi.org/10.1073/pnas.0903269107
    Journal articles | 2009
    Kilian KA; Boecking T; Gooding JJ, 2009, 'The importance of surface chemistry in mesoporous materials: Lessons from porous silicon biosensors', Chemical Communications, pp. 630 - 640
    Journal articles | 2009
    Kilian KA; Lai LH; Magenau AI; Cartland SP; Boecking T; Di Girolamo N; Gal M; Gaus K; Gooding JJ, 2009, 'Smart tissue culture: in Situ monitoring of the activity of protease enzymes secreted from live cells using nanostructured photonic crystals', Nano Letters, 9, pp. 2021 - 2025
    Journal articles | 2008
    Boecking T; Kilian KA; Gaus K; Gooding JJ, 2008, 'Modifying Porous Silicon with Self-Assembled Monolayers for Biomedical Applications: The Influence of Surface Coverage on Stability and Biomolecule Coupling', Advanced Functional Materials, 18, pp. 3827 - 3833
    Journal articles | 2008
    Ciampi S; Boecking T; Kilian KA; Harper JB; Gooding JJ, 2008, 'Click chemistry in mesoporous materials: Functionalization of porous silicon rugate filters', Langmuir, 24, pp. 5888 - 5892
    Journal articles | 2008
    Kilian KA; Boecking T; Gaus K; Gooding JJ, 2008, 'Introducing distinctly different chemical functionalities onto the internal and external surfaces of mesoporous materials', Angewandte Chemie (International Edition), 47, pp. 2697 - 2699, http://dx.doi.org/10.1002/anie.200704784
    Journal articles | 2008
    Kilian KA; Boecking T; Lai LH; Ilyas S; Gaus K; Gal M; Gooding JJ, 2008, 'Organic modification of mesoporous silicon rugate filters: The influence of nanoarchitecture on optical behaviour', INTERNATIONAL JOURNAL OF NANOTECHNOLOGY, 5, pp. 170 - 178
    Journal articles | 2008
    Kilian KA; Böcking T; Gaus K; Gooding JJ, 2008, 'Introducing Distinctly Different Chemical Functionalities onto the Internal and External Surfaces of Mesoporous Materials', Angewandte Chemie, 120, pp. 2737 - 2739, http://dx.doi.org/10.1002/ange.200704784
    Journal articles | 2007
    Ciampi S; Boecking T; Kilian KA; James M; Harper JB; Gooding JJ, 2007, 'Functionalization of acetylene-terminated monolayers on Si(100) surfaces: A click chemistry approach', Langmuir, 23, pp. 9320 - 9329, http://dx.doi.org/10.1021/la701035g
    Journal articles | 2007
    Ilyas S; Boecking T; Kilian KA; Reece PJ; Gooding JJ; Gaus K; Gal M, 2007, 'Porous silicon based narrow line-width rugate filters', Optical Materials, 29, pp. 619 - 622, http://dx.doi.org/10.1016/j.optmat.2005.10.012
    Journal articles | 2007
    Kilian KA; Boecking T; Gaus K; Gal M; Gooding JJ, 2007, 'Peptide-modified optical filters for detecting protease activity', ACS NANO, 1, pp. 355 - 361
    Journal articles | 2007
    Kilian KA; Boecking T; Gaus K; Gal M; Gooding JJ, 2007, 'Si-C linked oligo(ethylene glycol) layers in silicon-based photonic crystals: Optimization for implantable optical materials', Biomaterials, 28, pp. 3055 - 3062, http://dx.doi.org/10.1016/j.biomaterials.2007.03.014
    Journal articles | 2007
    Kilian KA; Boecking T; Gaus K; King-Lacroix J; Gal M; Gooding JJ, 2007, 'Hybrid lipid bilayers in nanostructured silicon: a biomimetic mesoporous scaffold for optical detection of cholera toxin', Chemical Communications, pp. 1936 - 1938
    Journal articles | 2007
    Kilian KA; Ilyas S; Jessup W; Gal M; Gooding JJ; Boecking T; Gaus K, 2007, 'Forming antifouling organic multilayers on porous silicon rugate filters towards in vivo/ex vivo biophotonic devices', Advanced Functional Materials, 17, pp. 2884 - 2890, http://dx.doi.org/10.1002/adfm.200600790
    Journal articles | 2006
    Bocking T; Killan KA; Gaus K; Gooding JJ, 2006, 'Single-step DNA immobilization on antifouling self-assembled monolayers covalently bound to silicon (111)', LANGMUIR, 22, pp. 3494 - 3496, http://dx.doi.org/10.1021/la060331a
    Journal articles | 2006
    Boecking T; Kilian KA; Gaus K; Gooding JJ, 2006, 'Single-Step DNA Immobilization on Antifouling Self-Assembled Monolayers Covalently Bound to Silicon (111)', Langmuir, 22, pp. 3494 - 3496
    Journal articles | 2005
    Boecking T; Kilian KA; Hanley T; Ilyas S; Gaus K; Gal M; Gooding JJ, 2005, 'The Formation of Tetraethylene Oxide Terminated Si-C Linked Monolayers and their Derivation of with Glycine: An example of a generic strategy for the modification of silicon surfaces with biomolecules', Langmuir, 21, pp. 10522 - 10529
    Journal articles | 2004
    Cleary MA; Kilian K; Wang Y; Bradshaw J; Cavet G; Ge W; Kulkarni A; Paddison PJ; Chang K; Sheth N; Leproust E; Coffey EM; Burchard J; McCombie WR; Linsley P; Hannon GJ, 2004, 'Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis', Nature Methods, 1, pp. 241 - 248, http://dx.doi.org/10.1038/nmeth724
    Journal articles | 2003
    Fare TL; Coffey EM; Dai H; He YD; Kessler DA; Kilian KA; Koch JE; LeProustt E; Marton MJ; Meyer MR; Stoughton RB; Tokiwa GY; Wang Y, 2003, 'Effects of atmospheric ozone on microarray data quality', Analytical Chemistry, 75, pp. 4672 - 4675, http://dx.doi.org/10.1021/ac034241b
  • Preprints | 2024
    Altevogt L; Sheikh R; Molley T; Yong J; Liang K; Spicer P; Kilian K; Wich P, 2024, Enzyme Bioink for the 3D Printing of Biocatalytic Materials, http://dx.doi.org/10.1101/2024.02.04.577699
    Preprints | 2024
    Putra V; Kilian K; Knothe Tate M, 2024, Stem cell mechanoadaptation Part B - Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling, http://dx.doi.org/10.1101/2024.07.28.605537
    Preprints | 2024
    Putra V; Kilian K; Tate MK, 2024, Stem cell mechanoadaptation - Part A - Effect of microtubule stabilization and volume changing stresses on cytoskeletal remodeling, http://dx.doi.org/10.1101/2024.07.28.605421
    Other | 2023
    Huang Y; Jayathilaka PB; Islam MS; Tanaka CB; Silberstein MN; Kilian KA; Kruzic JJ, 2023, Corrigendum to ‘Structural aspects controlling the mechanical and biological properties of tough, double network hydrogels’ [Acta Biomaterialia 138 (2022) 301–312, (S1742706121007133), (10.1016/j.actbio.2021.10.044)], http://dx.doi.org/10.1016/j.actbio.2023.02.007
    Conference Abstracts | 2022
    Jayathilaka H; Molley T; Haung Y; Islam S; Silberstein M; Kruzic J; Kilian K, 2022, 'FORCE-MEDIATED MOLECULE RELEASING TOUGH HYDROGEL BIOMATERIAL FOR TISSUE ENGINEERING APPLICATIONS', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, Vol. 28, pp. S543 - S543, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000821187303043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2022
    Molley T; Jiang S; Kopecky C; Ranaweera C; Jalandhra G; Rnjak-Kovacina J; Kilian K, 2022, Gas modulating microcapsules for spatiotemporal control of hypoxia, http://dx.doi.org/10.1101/2022.09.02.506302
    Conference Abstracts | 2022
    Srivastava P; Romanazzo S; Ireland JB; Pimanda JE; Kilian KA, 2022, 'BIOPHYSICAL REGULATION OF IN-VITRO GASTRULATION USING INDUCED PLURIPOTENT STEM CELLS', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, Vol. 28, pp. S518 - S519, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000821187302276&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2021
    Srivastava P; Romanazzo S; Ireland J; Nemec S; Molley T; Jayathilaka P; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, 2021, Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells, http://dx.doi.org/10.1101/2021.10.28.466327
    Preprints | 2019
    Fanous M; Li Y; Kandel M; Kilian K; Popescu G, 2019, Patterned substrates modulate growth and dynamics of 3D cellular systems, http://dx.doi.org/10.1101/632034
    Conference Papers | 2017
    Kononov A; Bellon P; Bretl T; Ferguson AL; Herman GL; Kilian KA; Krogstad JA; Leal C; Maass R; Schleife A; Shang JK; Trinkle DR; West M, 2017, 'Computational curriculum for MatSE undergraduates', in ASEE Annual Conference and Exposition, Conference Proceedings, American Society for Engineering Education, presented at 2017 ASEE Annual Conference & Exposition Proceedings, 24 June 2017 - 28 June 2017, http://dx.doi.org/10.18260/1-2--28060
    Conference Papers | 2017
    Le P; Kilian K; Smith A, 2017, 'Abstract 2919: Quantitative mapping of epidermal growth factor receptor activation in single breast cancer cells treated with targeted therapies', in Cancer Research, American Association for Cancer Research (AACR), pp. 2919 - 2919, http://dx.doi.org/10.1158/1538-7445.am2017-2919
    Preprints | 2017
    Sridharan S; Li Y; Foucard L; Majeed H; Bhaduri B; Levine A; Kilian K; Popescu G, 2017, Simultaneous cell traction and growth measurements using light, http://dx.doi.org/10.1101/206649
    Conference Papers | 2016
    Sridharan S; Li Y; Bhaduri B; Majeed H; Dupenloup P; Levine A; Kilian KA; Popescu G, 2016, 'Hilbert phase dynamometry (HPD) for real-time measurement of cell generated forces (Conference Presentation)', in Popescu G; Park Y (ed.), Quantitative Phase Imaging II, SPIE, pp. 58 - 58, presented at Quantitative Phase Imaging II, 13 February 2016 - 18 February 2016, http://dx.doi.org/10.1117/12.2216261
    Conference Papers | 2014
    Kilian K; Abdeen A; Huang T; Li Y; Lee J; Zhang D; Sun M; Mo S; Kim A; Tang C; Barbero M, 2014, 'Engineering cell fate by controlling cell-matrix interactions on geometrically defined surfaces', in 4th International Conference on Stem Cell Engineering 2014, pp. 38 - 49
    Conference Papers | 2010
    Kilian KA; Magenau AI; Boecking T; Gaus K; Gal M; Gooding JJ, 2010, 'Silicon-based mesoporous photonic crystals: towards single cell optical biosensors', in Biosensing II. Proceedings of SPIE Volume: 7397, SPIE, San Diego, USA, pp. 739703-1 - 739703-8, presented at SPIE Optics & Photonics, San Diego, USA, 01 August 2010 - 05 August 2010, http://dx.doi.org/10.1117/12.826133
    Conference Papers | 2007
    Kilian KA; Boecking T; Ciampi S; Gaus K; Gal M; Gooding JJ, 2007, 'The modification of flat and porous silicon surface with organic monolayers for the capture and detection of biomolecules', in Quake S; Heath JR (ed.), Keystone Symposium on Nanotechnology in Biomedicine, USA, pp. 46 - 46, presented at Keystone Symposium on Nanotechnology in Biomedicine, Tahoe City, USA, 11 February 2007 - 16 February 2007
    Theses / Dissertations | 2007
    Kilian KA; Gooding JJ, 2007, Chemical and biological modification of porous silicon photonic crystals
    Conference Abstracts | 2007
    Kilian KA; Lai LMH; Boecking T; Ilyas S; Gaus K; Gal M; Gooding JJ, 2007, 'Covalently bound biopolymers within mesoporous silicon as improved substrates for optical detection of enzyme activity', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, IL, Chicago, Vol. 233, pp. 62 - 62, presented at 233rd National Meeting of the Cellulose-and-Renewable-Materials-Division of the American-Chemical-Society (ACS), IL, Chicago, 25 March 2007 - 29 March 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207722805053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Kilian KA; Bocking T; Ilyas S; Gaus K; Gal M; Gooding JJ, 2006, 'Optimisation of Nanostructured Porous Silicon Surface Chemistry Towards Biophotonic Sensors', in 2006 INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY, VOLS 1 AND 2, IEEE, AUSTRALIA, Brisbane, pp. 671 - +, presented at International Conference on Nanoscience and Nanotechnology, AUSTRALIA, Brisbane, 03 July 2006 - 07 July 2006, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249051500173&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Kilian KA; Boecking T; Ilyas S; Gal M; Gaus K; Gooding JJ, 2006, 'Optimisation of Nanstructured Porous Silicon Surface Chemistry Towards Biophotonic Sensors', in Jagadirh J; Lu M (ed.), International Conference on Nanoscience and Nanotechnology, Brisbane, Qld, pp. 193 - 193, presented at ICONN 2006: International Conference on Nanoscience and Nanotechnology, Brisbane, Qld, 03 July 2006 - 07 July 2006
    Conference Papers | 2006
    Kilian KA; Böcking T; Ilyas S; Gaus K; Gal M; Gooding JJ, 2006, 'Optimisation of nanostructured porous silicon surface chemistry towards biophotonic sensors', in Proceedings of the 2006 International Conference on Nanoscience and Nanotechnology, ICONN, pp. 486 - 489, http://dx.doi.org/10.1109/ICONN.2006.340659
    Conference Papers | 2005
    Boecking T; Ilyas S; Kilian KA; Salvador GP; Reece PJ; Gaus K; Gal M; Gooding JJ, 2005, 'Covalent modification of flat single crystal and porous silicon surfaces for biosensor applications', in Australian Colloid Interface Science Conference 2005, Coogee, NSW, pp. 149 - 149, presented at Australian Colloid Interface Science Conference 2005, Coogee, NSW, 13 February 2005 - 17 February 2005
    Conference Papers | 2005
    Kilian KA; Boecking T; Ilyas S; Gaus K; Gal M; Gooding JJ, 2005, 'Organic Modification of Porous Silicon Photonic Crystals for Biological Sensing Applications', in Apte S; Kable S; Baker AT (eds.), Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Convention Centre, Darling Harbour, Sydney, pp. M026 PO Bi/Or - na, presented at Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Convention Centre, Darling Harbour, Sydney, 03 July 2005 - 07 July 2005

  1. We are an interdisciplinary research group at UNSW Sydney with a broad goal to design materials that unravel ‘matrix structure-cell function’ relationships. Inspired by biological materials, we integrate nano- and micro- fabrication techniques with synthetic chemistry to mimic the physical and chemical properties of the cell and tissue microenvironment. Our overarching strategy is to:
  1. Develop synthetic model systems to address fundamental questions in cell biology.
  2. Use the output from 1 to design biomaterials that direct a functional outcome for commercial and clinical translation (e.g., cell differentiation and de-differentiation)

All our efforts are centred on the idea that cell state and fate is ruled by inherent cell plasticity and the context in which multivariate signals are presented.

Current projects include:

  • Designer matrices for stem cell manufacture
  • iPSC derived organoid bioengineering
  • Tumor microenvironments and models for drug development
  • Tissue engineering for lab-grown meat
  • 4D Biofabrication
  • Dynamic hydrogels and mechanochemistry