Associate Professor Luke Hesson

Hesson LB; Pritchard AL, 2019, 'Genetics and Epigenetics: A Historical Overview', in Clinical Epigenetics, Springer Singapore, pp. 1 - 46, http://dx.doi.org/10.1007/978-981-13-8958-0_1

Hesson LB; Sloane MA; Pritchard AL, 2019, 'The Clinical Utility of Epigenetics: A Case Study', in Clinical Epigenetics, Springer Singapore, pp. 247 - 265, http://dx.doi.org/10.1007/978-981-13-8958-0_11

Kuroiwa-Trzmielina J; Hesson LB, 2016, 'Epigenetic Effects of Gut Microbiota on Obesity and Gastrointestinal Cancers', in Berger NA (ed.), EPIGENETICS, ENERGY BALANCE, AND CANCER, edn. Energy Balance and Cancer, SPRINGER INTERNATIONAL PUBLISHING AG, pp. 167 - 189, http://dx.doi.org/10.1007/978-3-319-41610-6_7

Bournazos AM; Riley LG; Bommireddipalli S; Ades L; Akesson LS; Al-Shinnag M; Alexander SI; Archibald AD; Balasubramaniam S; Berman Y; Beshay V; Boggs K; Bojadzieva J; Brown NJ; Bryen SJ; Buckley MF; Chong B; Davis MR; Dawes R; Delatycki M; Donaldson L; Downie L; Edwards C; Edwards M; Engel A; Ewans LJ; Faiz F; Fennell A; Field M; Freckmann ML; Gallacher L; Gear R; Goel H; Goh S; Goodwin L; Hanna B; Harraway J; Higgins M; Ho G; Hopper BK; Horton AE; Hunter MF; Huq AJ; Josephi-Taylor S; Joshi H; Kirk E; Krzesinski E; Kumar KR; Lemckert F; Leventer RJ; Lindsey-Temple SE; Lunke S; Ma A; Macaskill S; Mallawaarachchi A; Marty M; Marum JE; McCarthy HJ; Menezes MP; McLean A; Milnes D; Mohammad S; Mowat D; Niaz A; Palmer EE; Patel C; Patel SG; Phelan D; Pinner JR; Rajagopalan S; Regan M; Rodgers J; Rodrigues M; Roxburgh RH; Sachdev R; Roscioli T; Samarasekera R; Sandaradura SA; Savva E; Schindler T; Shah M; Sinnerbrink IB; Smith JM; Smith RJ; Springer A; Stark Z; Strom SP; Sue CM; Tan K; Tan TY; Tantsis E; Tchan MC; Thompson BA; Trainer AH; van Spaendonck-Zwarts K; Walsh R; Warwick L; White S; White SM; Williams MG, 2022, 'Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants', Genetics in Medicine, vol. 24, pp. 130 - 145, http://dx.doi.org/10.1016/j.gim.2021.09.001

Lin V; Chung IY; Toumi E; McKay D; McKenzie J; McKelvie P; Zabih F; Hoffmeister A; Wright D; Ntzaferi A; Wu IJ; Hesson L; Fung A; Lim LA; Wong S; Field A; Earls P; Giblin M; Conway RM; Cherepanoff S, 2022, 'Biopsy for molecular risk stratification in uveal melanoma: Yields and molecular characteristics in 119 patients', Clinical and Experimental Ophthalmology, vol. 50, pp. 50 - 61, http://dx.doi.org/10.1111/ceo.14022

Gifford G; Hesson L; Wong JWH; Carroll A; Gabrielli S; Bai LJ; Xia W; Stevenson W; Greenwood M, 2021, 'Poor mobilization of autologous CD34⁺ peripheral blood stem cells in haematology patients undergoing autologous stem cell transplantation is associated with the presence of variants in genes implicated in clonal haematopoiesis of indeterminant potential', British Journal of Haematology, vol. 193, pp. 841 - 844, http://dx.doi.org/10.1111/bjh.17316

Palmer EE; Sachdev R; Macintosh R; Melo US; Mundlos S; Righetti S; Kandula T; Minoche AE; Puttick C; Gayevskiy V; Hesson L; Idrisoglu S; Shoubridge C; Thai MHN; Davis RL; Drew AP; Sampaio H; Andrews PI; Lawson J; Cardamone M; Mowat D; Colley A; Kummerfeld S; Dinger ME; Cowley MJ; Roscioli T; Bye A; Kirk E, 2021, 'Diagnostic Yield of Whole Genome Sequencing After Nondiagnostic Exome Sequencing or Gene Panel in Developmental and Epileptic Encephalopathies', Neurology, vol. 96, pp. e1770 - e1782, http://dx.doi.org/10.1212/WNL.0000000000011655

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Srivastava P; Potas JR; Hung T; Power C; Hardy P; Ma DD; Kilian KA; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, 2021, 'Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine', Science Advances, vol. 7, pp. eabd1929 - eabd1929, http://dx.doi.org/10.1126/sciadv.abd1929

Morris MJ; Hesson LB; Youngson NA, 2020, 'Non-CpG methylation biases bisulphite PCR towards low or unmethylated mitochondrial DNA: recommendations for the field', ENVIRONMENTAL EPIGENETICS, vol. 6, http://dx.doi.org/10.1093/eep/dvaa001

Van Ly D; Wang D; Conway RM; Giblin M; Liang S; Lukeis R; Lim LA; Hesson L; Cherepanoff S, 2020, 'Lipid-Producing Ciliochoroidal Melanoma with Expression of HMG-CoA Reductase', Ocular Oncology and Pathology, vol. 6, pp. 416 - 421, http://dx.doi.org/10.1159/000510393

Yeola A; Subramanian S; Oliver R; Lucas C; Thoms J; Yan F; Olivier J; Chacon D; Tursky M; Hung T; Power C; Hardy P; Ma D; McCarroll J; Kavallaris M; Hesson L; Beck D; Curtis D; Wong JWH; Hardeman E; Walsh W; Mobbs R; Chandrakanthan V; Pimanda J, 2020, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', , http://dx.doi.org/10.1101/2020.06.04.130872

Poulos RC; Perera D; Packham D; Shah A; Janitz C; Pimanda JE; Hawkins N; Ward RL; Hesson LB; Wong JWH, 2019, 'Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing', JNCI CANCER SPECTRUM, vol. 3, http://dx.doi.org/10.1093/jncics/pkz012

Berbic M; Hesson L; Ho LL; Kyle P; Mina K, 2018, 'Case study – Reproductive risk of clinically relevant thalassaemia despite mild microcytosis and normal thalassaemia screen', Pathology, vol. 50, pp. S63 - S63, http://dx.doi.org/10.1016/j.pathol.2017.12.148

Jacquelin S; Straube J; Cooper L; Vu T; Song A; Bywater M; Baxter E; Heidecker M; Wackrow B; Porter A; Ling V; Green J; Austin R; Kazakoff S; Waddell N; Hesson LB; Pimanda JE; Stegelmann F; Bullinger L; Döhner K; Rampal RK; Heckl D; Hill GR; Lane SW, 2018, 'Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation', Blood, vol. 132, pp. 2707 - 2721, http://dx.doi.org/10.1182/blood-2018-04-846220

Liu Q; Thoms JAI; Nunez AC; Huang Y; Knezevic K; Packham D; Poulos RC; Williams R; Beck D; Hawkins NJ; Ward RL; Wong JWH; Hesson LB; Sloane MA; Pimanda JE, 2018, 'Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cells', Clinical Cancer Research, vol. 24, pp. 4602 - 4611, http://dx.doi.org/10.1158/1078-0432.CCR-17-3678

Morris MJ; Hesson LB; Poulos RC; Ward RL; Wong JWH; Youngson NA, 2018, 'Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation', Biomarker Research, vol. 6, pp. 37, http://dx.doi.org/10.1186/s40364-018-0151-x

Unnikrishnan A; Vo ANQ; Pickford R; Raftery MJ; Nunez AC; Verma A; Hesson LB; Pimanda JE, 2018, 'AZA-MS: A novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo', Leukemia, vol. 32, pp. 900 - 910, http://dx.doi.org/10.1038/leu.2017.340

Jacquelin S; Straube J; Song A; Cooper L; Vu T; Heidecker M; Pimanda J; Hesson L; Hill G; Cloonan N; Heckl D; Lane S, 2017, 'In vivo CRISPR editing of DNMT3A in JAK2V617F hematopoietic stem cells induces myelofibrosis', Experimental Hematology, vol. 53, pp. S95 - S95, http://dx.doi.org/10.1016/j.exphem.2017.06.224

Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The microbiota and epigenetic regulation of t helper 17/regulatory T cells: In search of a balanced immune system', Frontiers in Immunology, vol. 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417

Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2017, 'Validation of specificity of antibodies for immunohistochemistry: the case of ROR2', Virchows Archiv : an international journal of pathology, vol. 470, pp. 99 - 108, http://dx.doi.org/10.1007/s00428-016-2019-5

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Hesson LB; Ng B; Zarzour P; Srivastava S; Kwok CT; Packham D; Nunez AC; Beck D; Ryan R; Dower A; Ford CE; Pimanda JE; Sloane MA; Hawkins NJ; Bourke MJ; Wong JWH; Ward RL, 2016, 'Integrated genetic, epigenetic, and transcriptional profiling identifies molecular pathways in the development of laterally spreading tumors', Molecular Cancer Research, vol. 14, pp. 1217 - 1228, http://dx.doi.org/10.1158/1541-7786.MCR-16-0175

Liu Q; Hesson LB; Nunez AC; Packham D; Hawkins NJ; Ward RL; Sloane MA, 2016, 'Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients', Cancer Genetics, vol. 209, pp. 497 - 500, http://dx.doi.org/10.1016/j.cancergen.2016.10.001

Liu Q; Hesson LB; Nunez AC; Packham D; Williams R; Ward RL; Sloane MA, 2016, 'A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome', Carcinogenesis, vol. 37, pp. 10 - 17, http://dx.doi.org/10.1093/carcin/bgv154

Liu Q; Thompson BA; Ward RL; Hesson LB; Sloane MA, 2016, 'Understanding the Pathogenicity of Noncoding Mismatch Repair Gene Promoter Variants in Lynch Syndrome', Human Mutation, vol. 37, pp. 417 - 426, http://dx.doi.org/10.1002/humu.22971

Ma S; srivastava S; llamosas E; hawkins N; hesson L; ward R; Ford C, 2016, 'ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.', BMC Cancer, vol. 16, http://dx.doi.org/10.1186/s12885-016-2576-7

Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2016, 'Erratum to: Validation of specificity of antibodies for immunohistochemistry: the case of ROR2 (Virchows Archiv, (2016), 10.1007/s00428-016-2019-5)', Virchows Archiv, vol. 469, pp. 717, http://dx.doi.org/10.1007/s00428-016-2036-4

Sloane MA; Ward RL; Hesson LB, 2016, 'Defining the criteria for identifying constitutional epimutations', Clinical Epigenetics, vol. 8, http://dx.doi.org/10.1186/s13148-016-0207-4

Srivastava S; Ludwig AK; Wong JWH; Hesson LB, 2016, 'An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer', Gene, vol. 585, pp. 154 - 158, http://dx.doi.org/10.1016/j.gene.2016.03.031

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15

Youngson N; Lecomte V; Maloney C; Leung P; Liu J; Hesson L; Luciani F; Krause L; Morris M, 2016, 'Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring', Asian Journal of Andrology, vol. 18, pp. 930 - 936, http://dx.doi.org/10.4103/1008-682X.163190

Hesson LB; Packham D; Kwok CT; Nunez AC; Ng B; Schmidt C; Fields M; Wong JW; Sloane MA; Ward RL, 2015, 'Lynch Syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.', Human Mutation, vol. 36, pp. 622 - 630, http://dx.doi.org/10.1002/humu.22785

Poulos RC; Sloane MA; Hesson LB; Wong JWH, 2015, 'The search for cis-regulatory driver mutations in cancer genomes', Oncotarget, vol. 6, pp. 32509 - 32525, http://dx.doi.org/10.18632/oncotarget.5085

Sloane MA; Nunez AC; Packham D; Kwok CT; Suthers G; Hesson LB; Ward RL, 2015, 'Mosaic epigenetic inheritance as a cause of early-onset colorectal cancer', JAMA Oncology, vol. 1, pp. 953 - 957, http://dx.doi.org/10.1001/jamaoncol.2015.1484

Zarzour P; Boelen L; Luciani F; Beck D; Sakthianandeswaren A; Mouradov D; Sieber OM; Hawkins NJ; Hesson LB; Ward RL; Wong JWH, 2015, 'Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas', Genes Chromosomes and Cancer, vol. 54, pp. 303 - 314, http://dx.doi.org/10.1002/gcc.22243

Hesson LB; Sloane MA; Wong JWH; Nunez AC; Srivastava S; Ng B; Hawkins NJ; Bourke MJ; Ward RL, 2014, 'Altered promoter nucleosome positioning is an early event in gene silencing', Epigenetics, vol. 9, pp. 1422 - 1430, http://dx.doi.org/10.4161/15592294.2014.970077

Hesson LB; Ward RL, 2014, 'Discrimination of pseudogene and parental gene dna methylation using allelic bisulfite sequencing', Methods in Molecular Biology, vol. 1167, pp. 265 - 274, http://dx.doi.org/10.1007/978-1-4939-0835-6_18

Hesson LB; Ward RL, 2014, 'The importance of distinguishing pseudogenes from parental genes', Clinical Epigenetics, vol. 6, pp. 90, http://dx.doi.org/10.1186/s13148-014-0033-5

Patil V; Ward RL; Hesson LB, 2014, 'The evidence for functional non-CpG methylation in mammalian cells', Epigenetics, vol. 9, pp. 823 - 828, http://dx.doi.org/10.4161/epi.28741

Simar D; Versteyhe S; Donkin I; Liu J; Hesson L; Nylander V; Fossum A; Barres R, 2014, 'DNA Methylation Is Altered In B And NK Lymphocytes In Obese And Type 2 Diabetic Human', Metabolism: clinical and experimental, vol. 63, pp. 1188 - 1197, http://dx.doi.org/10.1016/j.metabol.2014.05.014

Sloane MA; Hesson LB; Nunez AC; Thompson BA; Ward RL, 2014, 'Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients', Clinical Epigenetics, vol. 6, pp. 32 - 32, http://dx.doi.org/10.1186/preaccept-1571082317134727

Sloane MA; Hesson LB; Nunez AC; Thompson BA; Ward RL, 2014, 'Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients', Clinical Epigenetics, vol. 6, http://dx.doi.org/10.1186/s13148-014-0032-6

Sloane MA; Hesson LB; Ward RL, 2014, 'Epimutations and cancer susceptibility', eLS, vol. Published Online: 17 MAR 2014, pp. 1 - 10, http://dx.doi.org/10.1002/9780470015902.a0024615

Sloane MA; Wong JWH; Perera D; Nunez AC; Pimanda JE; Hawkins NJ; Sieber OM; Bourke MJ; Hesson LB; Ward RL, 2014, 'Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia', Epigenetics, vol. 9, pp. 1092 - 1100, http://dx.doi.org/10.4161/epi.29222

Hesson L, 2013, 'Gut microbiota and obesity-related gastrointestinal cancer: a focus on epigenetics', Translational Gastrointestinal Cancer, vol. 2, pp. 204 - 210

Hesson LB; Patil V; Sloane MA; Nunez AC; Liu J; Pimanda JE; Ward RL, 2013, 'Reassembly of Nucleosomes at the MLH1 Promoter Initiates Resilencing Following Decitabine Exposure', PLoS Genetics, vol. 9, http://dx.doi.org/10.1371/journal.pgen.1003636

Liu J; Hesson LB; Ward RL, 2013, 'Liquid chromatography tandem mass spectrometry for the measurement of global DNA methylation and hydroxymethylation', Journal of Proteomics & Bioinformatics, vol. 01, http://dx.doi.org/10.4172/jpb.S2-005

Metz AJ; Bourke MJ; Moss A; Dower A; Zarzour P; Hawkins NJ; Ward RL; Hesson L, 2013, 'A correlation of the endoscopic characteristics of colonic laterally spreading tumours (LSTs) with genetic alterations', European Journal of Gastroenterology and Hepatology, vol. 25, pp. 319 - 326, http://dx.doi.org/10.1097/MEG.0b013e32835b57e7

Zarzour P; Hesson LB; Ward RL, 2013, 'Establishing the clinical utility of epigenetic markers in cancer: Many challenges ahead', Epigenomics, vol. 5, pp. 513 - 523, http://dx.doi.org/10.2217/epi.13.53

Hesson L; Packham D; Pontzer E; Funchain P; Eng C; Ward RL, 2012, 'A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines', Biological Procedures Online, vol. 14, pp. 1 - 8, http://dx.doi.org/10.1186/1480-9222-14-5

Hesson LB; Wong JWH; Sloane MA; Pimanda JE; Bourke MJ; Hawkins NJ; Ward RL, 2012, 'Nucleosome occupancy at unmethylated promoter CpG islands represents a novel mechanism of epigenetic gene silencing in cancer', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-990

Lau DT; Hesson L; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma', Clinical Cancer Research, vol. 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294

Lau DT; Hesson LB; Norris MD; Haber M; Marshall GM; Ashton LJ, 2012, 'Prognostic significance of promoter DNA methylation in patients with neuroblastoma', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1425

Lau DT; Hesson LB; Norris MD; Marshall G; Haber M; Ashton LJ, 2012, 'Abstract 68: Beyond GWAS: The prognostic significance of promoter DNA methylation in patients with neuroblastoma.', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, pp. 68 - 68, http://dx.doi.org/10.1158/1055-9965.gwas-68

Liu J; Hesson L; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', CANCER PREVENTION RESEARCH, vol. 5, pp. 921 - 929, http://dx.doi.org/10.1158/1940-6207.CAPR-11-0577

Hesson LB; Latif F, 2011, 'RASSF2 (Ras association (RalGDS/AF-6) domain family member 2)', Atlas of Genetics and Cytogenetics in Oncology and Haematology, http://dx.doi.org/10.4267/2042/44798

Hesson LB; Latif F, 2011, 'RASSF6 (Ras association (RalGDS/AF-6) domain family member 6)', Atlas of Genetics and Cytogenetics in Oncology and Haematology, http://dx.doi.org/10.4267/2042/44939

Hesson LB; Patil V; Sloane M; Ward RL, 2011, 'Investigation of the molecular events associated with gene resilencing following withdrawal of epigenetic therapies', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-2000

Liu JJ; Hesson LB; Rand KN; Molloy PL; Pimanda J; Ward RL, 2011, 'Analysis of global and repeat sequence DNA methylation in the blood and normal colonic mucosa of colorectal cancer patients, healthy individuals and patients with folate deficiency', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-91

Dunwell TL; Hesson L; Rauch TA; Wang L; Clark R; Dallol A; Gentle D; Catchpoole DR; Maher ER; Pfeifer G; Latif F, 2010, 'A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers', Molecular Cancer, vol. 9, pp. 44 - 44

Hesson L; Donninger H; Latif F; Vos MD; Beebe K; Gordon L; Sidransky D; Liu JW; Schlegel T; Payne S; Hartmann A, 2010, 'The Ras effector RASSF2 controls the PAR-4 tumor suppressor.', Molecular and Cellular Biology, vol. 30, pp. 2608 - 2620

Hesson L; Hitchins MP; Ward RL, 2010, 'Epimutations and cancer predisposition: importance and mechanisms', Current Opinion in Genetics and Development, vol. 20, pp. 1 - 9, http://dx.doi.org/10.1016/j.gde.2010.02.005

Hill VK; Hesson L; Dansranjavin T; Dallol A; Bieche I; Vacher S; Tommasi S; Dobbins TA; Gentle D; Euhus D; Dammann R; Ward RL; Minna JD; Maher ER; Pfeifer G; Latif F, 2010, 'Identification of 5 novel genes methylated in breast and other epithelial cancers', Molecular Cancer Research, vol. 9, pp. 51 - 66, http://dx.doi.org/10.1186/1476-4598-9-51

Lock FE; Underhill-Day N; Dunwell TL; Matallanas D; Cooper W; Hesson L; Recino A; Ward A; Pavlova TV; Zabarovsky ER; Grant M; Maher ER; Chalmers AD; Kolch W; Latif F, 2010, 'The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kB signaling pathways', Oncogene, vol. 29, pp. 4307 - 4316

Cooper W; Hesson L; Matallanas D; Dallol A; Von Kriegsheim A; Ward RL; Kolch W; Latif F, 2009, 'RASSF2 associates with and stabilizes the proapoptotic kinase MST2', Oncogene, vol. 28, pp. 2988 - 2998, http://dx.doi.org/10.1038/onc.2009.152

Dallol A; Hesson L; Matallanas D; Cooper WN; O''neill E; Maher ER; Kolch W; Latif F, 2009, 'Ran GTPase is a RASSF1A effector involved in controlling microtubule organisation', Ran GTPase is a RASSF1A effector involved in controlling microtubule organisation, vol. 19, pp. 1227 - 1232

Dunwell TL; Hesson L; Pavlova TV; Zabarovska V; Kashuba V; Catchpoole DR; Chiaramonte R; Brini AT; Griffiths M; Maher ER; Zabarovsky ER; Latif F, 2009, 'Epigenetic analysis of childhood acute lymphoblastic leukemia', Epigenetic analysis of childhood acute lymphoblastic leukemia, vol. 4, pp. 185 - 193

Hesson L; Dunwell TL; Cooper WN; Catchpoole DR; Brini AT; Chiaramonte R; Chalmers AD; Griffiths M; Maher ER; Latif F, 2009, 'The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias', Molecular Cancer, vol. 8, pp. 42 - 42

Cooper WN; Dickinson RE; Dallol A; Hesson LB; Bieche I; Clark GJ; Maher ER; Zabarovsky ER; Latif F, 2008, 'RASSF2 can suppress the growth of breast cancer cell lines and is epigenetically inactivated in breast tumours', Breast Cancer Research, vol. 10, http://dx.doi.org/10.1186/bcr1893

Hesson L; Krex D; Latif F, 2008, 'Epigenetic markers of human gliomas – prospects for therapeutic intervention', Expert Review of Neurotherapeutics, vol. 8, pp. 1475 - 1496

Morton S; Hesson L; Peggie M; Cohen P, 2008, 'Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma.', FEBS Letters, vol. 582, pp. 997 - 1002

Allen NPC; Donninger H; Vos MD; Eckfeld K; Hesson L; Gordon L; Birrer MJ; Latif F; Clark GJ, 2007, 'RASSF6 is a novel member of the RASSF family of tumor suppressors.', Oncogene, vol. 26, pp. 6203 - 6211

Cooper WN; Dickinson RE; Dallol A; Grigorieva EV; Pavlova TV; Hesson L; Bieche I; Broggini M; Maher ER; Zabarovsky ER; Clark GJ; Latif F, 2007, 'Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer', Oncogene, vol. 27, pp. 1805 - 1811

Hesson L; Cooper WN; Latif F, 2007, 'Evaluation of the 3p21.3 Tumour-suppressor Gene Cluster', Oncogene, vol. 26, pp. 7283 - 7301

Hesson L; Cooper WN; Latif F, 2007, 'The role of RASSF1A methylation in cancer', Disease Markers, vol. 23, pp. 73 - 87

Vos MD; Dallol A; Eckfeld K; Allen NPC; Donninger H; Hesson L; Calvisi D; Latif F; Clark GJ, 2006, 'The RASSF1A tumor suppressor activates Bax via MOAP-1', The Journal of Biological Chemistry, vol. 281, pp. 4557 - 4563

Caren H; Ejeskar K; Fransson S; Hesson L; Latif F; Sjoberg RM; Krona C; Martinsson T, 2005, 'A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation', Molecular Cancer, vol. 4, pp. 10

Elam C; Hesson L; Vos MD; Eckfeld K; Ellis CA; Bell A; Krex D; Birrer MJ; Latif F; Clark GJ, 2005, 'RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential', Cancer research, vol. 65, pp. 3117 - 3125

Hesson L; Wilson R; Morton D; Walker M; Maher ER; Latif F, 2005, 'CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations', Oncogene, vol. 24, pp. 3987 - 3994

Dallol A; Agathanggelou A; Fenton SL; Hesson L; Ahmed-choudhury J; Vos MD; Clark GJ; Downward J; Maher ER; Latif F, 2004, 'RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics', Cancer research, vol. 64, pp. 4112 - 4116

Eckfeld K; Hesson L; Vos MD; Bieche I; Latif F; Clark GJ, 2004, 'RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family', Cancer research, vol. 64, pp. 8688 - 8693

Fenton SL; Dallol A; Agathanggelou A; Hesson L; Ahmed-choudhury J; Baksh S; Sardet C; Dammann R; Minna JD; Downward J; Maher ER; Latif F, 2004, 'Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene', Cancer research, vol. 64, pp. 102 - 107

Hesson L; Bieche I; Krex D; Criniere E; Hoang-xuan K; Maher ER; Latif F, 2004, 'Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas', Oncogene, vol. 23, pp. 2408 - 2419

Agathanggelou A; Dallol A; Zochbauer-muller S; Morrissey C; Honorio S; Hesson L; Martinsson T; Fong KM; Kuo MJ; Yuen PW; Maher ER; Minna JD; Latif F, 2003, 'Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers', Oncogene, vol. 22, pp. 1580 - 1588

Da silva NF; Gentle D; Hesson L; Morton D; Latif F; Maher ER, 2003, 'Analysis of the Birt-Hogg-Dube (BHD) tumour suppressor gene in sporadic renal cell carcinoma and colorectal cancer', Journal of Medical Genetics, vol. 40, pp. 820 - 824

Dallol A; Krex D; Hesson L; Eng C; Maher ER; Latif F, 2003, 'Frequent epigenetic inactivation of the SLIT2 gene in gliomas', Oncogene, vol. 22, pp. 4611 - 4616

Hesson L; Dallol A; Minna JD; Maher ER; Latif F, 2003, 'NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers', Oncogene, vol. 22, pp. 947 - 954

Morris MR; Hesson L; Wagner KJ; Morgan NV; Astuti D; Lees RD; Cooper WN; Lee J; Gentle D; Macdonald F; Kishida T; Grundy R; Yao M; Latif F; Maher ER, 2003, 'Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma', Oncogene, vol. 22, pp. 6794 - 6801

Poulos RC; Perera D; Packham D; Shah A; Janitz C; Pimanda JE; Hawkins N; Ward RL; Hesson LB; Wong JWH, 2018, In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer, http://dx.doi.org/10.1101/249300

Unnikrishnan A; Quynh AVN; Pickford R; Nunez A; Hesson L; Pimanda J, 2017, 'A NOVEL MASS SPECTROMETRY METHOD REVEALS THE INTRACELLULAR PHARMACOKINETICS OF AZACYTIDINE THERAPY IN VIVO', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, SPAIN, Madrid, Vol. 102, pp. 258 - 259, presented at 22nd Congress of the European-Hematology-Association, SPAIN, Madrid, 22 June 2017 - 25 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000404127002145&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Sloane M; Liu Q; Nunez A; Packham D; Kwok C-T; Suthers G; Du Sart D; Williams R; Hesson L; Ward R, 2015, 'TRANSLATING BASIC RESEARCH INTO THE CLINICAL MANAGEMENT OF FAMILIES WITH LYNCH SYNDROME', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 102 - 102, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Patil V; Sloane MA; Wong JW; Liu J; Ward RL; Hesson LB, 2013, 'Abstract 2983: Gene resilencing following decitabine therapy is initiated by nucleosome reoccupancy and is related to CpG island shore methylation.', in Cancer Research, American Association for Cancer Research (AACR), pp. 2983 - 2983, presented at Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2013-2983

Liu J; Hesson LB; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-3125

Sloane M; Hesson L; Wong J; Pimanda J; Bourke M; Hawkins N; Ward R, 2012, 'Inactivation of the deubiquitinase USP44 is an early event in the formation of colorectal cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-LB-375

Metz AJ; Bourke MJ; Moss A; Hesson L; Ward R, 2011, 'A Correlation of the Endoscopic Characteristics of Colonic Laterally Spreading Tumours (LSTS) With Genetic Mutations', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S191 - S191, presented at Conference on Digestive Disease Week 2011, IL, Chicago, 07 May 2011 - 10 May 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000290167300770&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hill V; Hesson L; Dansranjavin T; Dallol A; Bieche I; Tommasi S; Dobbins T; Gentle D; Euhus D; Dammann R; Ward RL; Minna J; Maher ER; Pfeifer G; Latif F, 2010, 'MIRA (methylated CpG island recovery assay) assay identifies frequently methylated genes in breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM10-165

Metz AJ; Bourke MJ; Moss A; Hesson L; Ward R, 2010, 'A correlation of the endoscopic characteristics of colonic laterally spreading tumours (LSTs) with genetic mutations', Vol. 25, pp. A78 - A78, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1