Dr Malcolm Gillies

Adjunct Fellow Levels A-C

MBiostat, University of Sydney

PhD (computational medicinal chemistry), Utrecht University

BSc(hons) (pharmacology), University of Sydney

Medicine & Health

School of Population Health

I am a biostatistician in the Medicines Intelligence Research Program at the School of Population Health, with particular experience working on linked administrative health data and primary care electronic health records.

My background is in pharmacology, computer science, critical appraisal of clinical research and medical writing. I've worked in the areas of drug adverse effects, child development, drug utilisation, acute care service use and patient reported outcome measures. My recent research relates to prescription opioids and ADHD.

Phone

+61-2-9348-0078

E-mail

malcolm.gillies@unsw.edu.au

Location

Building C29 HTH Level 5

Journal articles | 2025

Brett J; Cesta CE; Gillies MB; Bateman BT; Chan AYL; Cheng MCY; Cho Y; Choi E; Cohen JM; Donald S; Furu K; Gissler M; Gomes T; Havard A; Hernandez-Diaz S; Hsieh MHC; Huybrechts KF; Karlsson P; Kelty E; Lai ECC; Ledlie S; Wang T; Leinonen K; Parkin L; Reutfors J; Shin JY; Su CTT; Varney B; Wong ICK; Man KKC; Zoega H, 2025, 'Global Trends in Analgesic Opioid Use in Pregnancy: A Retrospective Cohort Study', Anesthesiology, 142, pp. 1100 - 1113, http://dx.doi.org/10.1097/ALN.0000000000005418

Journal articles | 2025

Bruno C; Cesta CE; Hjellvik V; Ulrichsen SP; Bjørk MH; Esen BÖ; Gillies MB; Gissler M; Havard A; Karlstad Ø; Leinonen MK; Nørgaard M; Pearson SA; Reutfors J; Furu K; Cohen JM; Zoega H, 2025, 'Corrigendum to Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study [eClinicalMedicine 70 (2024) 102531/DOI: 10.1016/j.eclinm.2024.102531] (eClinicalMedicine (2024) 70, (S258953702400110X), (10.1016/j.eclinm.2024.102531))', Eclinicalmedicine, 81, http://dx.doi.org/10.1016/j.eclinm.2025.103139

Journal articles | 2025

Maston K; Gillies MB; Zoega H; Batterham PJ; Christensen H; Werner-Seidler A, 2025, 'Individual, social, and environmental predictors of insomnia symptom trajectories in a population cohort of Australian adolescents aged 13 to 17 years', Sleep Advances, 6, http://dx.doi.org/10.1093/sleepadvances/zpaf058

Journal articles | 2025

de Oliveira Costa J; Gillies MB; Schaffer AL; Zoega H; Peiris D; Pearson SA, 2025, 'New use of antidepressants among Australians up to 24 years of age remains high after the COVID-19 pandemic emergency era', Australian and New Zealand Journal of Psychiatry, 59, pp. 926 - 930, http://dx.doi.org/10.1177/00048674251356404

Journal articles | 2024

Brikell I; Yao H; Li L; Astrup A; Gao L; Gillies MB; Xie T; Zhang-James Y; Dalsgaard S; Engeland A; Faraone SV; Haavik J; Hartman C; Ip P; Jakobsdóttir Smári U; Larsson H; Man KK; de Oliveira Costa J; Pearson SA; Hostrup Nielsen NP; Snieder H; Wimberley T; Wong IC; Zhang L; Zoega H; Klungsøyr K; Chang Z, 2024, 'ADHD medication discontinuation and persistence across the lifespan: a retrospective observational study using population-based databases', Lancet Psychiatry, 11, pp. 16 - 26, http://dx.doi.org/10.1016/S2215-0366(23)00332-2

Journal articles | 2024

Bruno C; Cesta CE; Hjellvik V; Ulrichsen SP; Bjørk MH; Esen BÖ; Gillies MB; Gissler M; Havard A; Karlstad Ø; Leinonen MK; Nørgaard M; Pearson SA; Reutfors J; Furu K; Cohen JM; Zoega H, 2024, 'Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study', Eclinicalmedicine, 70, http://dx.doi.org/10.1016/j.eclinm.2024.102531

Journal articles | 2024

Gerhardy L; Nassar N; Litchfield M; Kennedy D; Smith A; Gillies MB; Pearson SA; Zoega H; Shand A, 2024, 'Prescription retinoid and contraception use in women in Australia: A population-based study', Australasian Journal of Dermatology, 65, pp. 428 - 436, http://dx.doi.org/10.1111/ajd.14294

Journal articles | 2024

Gillies MB; Bharat C; Camacho X; Daniels B; Hall K; Kelly TL; Kelty E; Lin J; Litchfield M; Lopez D; Noghrehchi F; Raubenheimer J; Varney B; Pratt N, 2024, 'Medicine utilization studies in Australian individual-level dispensing data: A blinded, multi-center replicated analysis', Pharmacoepidemiology and Drug Safety, 33, http://dx.doi.org/10.1002/pds.5776

Journal articles | 2024

Gillies MB; Camacho X; Bharat C; Buizen L; Blyth F; Currow D; Wilson A; Degenhardt L; Gisev N; Pearson SA, 2024, 'Oxycodone initiation in Australia (2014–2018): Sociodemographic factors and preceding health service use', British Journal of Clinical Pharmacology, 90, pp. 1656 - 1666, http://dx.doi.org/10.1111/bcp.16063

Journal articles | 2024

Gillies MB; Chidwick K; Bharat C; Camacho X; Currow D; Gisev N; Degenhardt L; Pearson SA, 2024, 'Long-term prescribed opioid use after hospitalization or emergency department presentation among opioid naïve adults (2014–2020)—A population-based descriptive cohort study', British Journal of Clinical Pharmacology, 90, pp. 2111 - 2123, http://dx.doi.org/10.1111/bcp.16093

Journal articles | 2024

Varney B; Brett J; Zoega H; Gillies MB; Powell M; Bateman BT; Shand AW; Pearson SA; Havard A, 2024, 'Opioid analgesic exposure during the first trimester of pregnancy and the risk of major congenital malformations in infants: a systematic review and meta-analysis†', Anaesthesia, 79, pp. 967 - 977, http://dx.doi.org/10.1111/anae.16307

Journal articles | 2024

Varney B; Zoega H; Bjørn Gillies M; Gisev N; Weston Shand A; Pearson S-A; Havard A, 2024, 'Prevalence and Persistence of Prescription Opioid Use Following Hospital Discharge After Childbirth: An Australian Population-Based Cohort Study', Obstetric Anesthesia Digest, 44, pp. 236 - 237, http://dx.doi.org/10.1097/01.aoa.0001080308.34895.4e

Journal articles | 2024

Varney B; Zoega H; Gillies MB; Gisev N; Weston Shand A; Pearson SA; Havard A, 2024, 'Prevalence and Persistence of Prescription Opioid Use Following Hospital Discharge after Childbirth: An Australian Population-Based Cohort Study', Anesthesia and Analgesia, 138, pp. 970 - 979, http://dx.doi.org/10.1213/ANE.0000000000006582

Journal articles | 2024

Zoega H; Falster M; Gillies M; Litchfield M; Camacho X; Bruno C; Daniels B; Donnolley N; Havard A; Schaffer A; Chambers G; Degenhardt L; Dobbins T; Gisev N; Ivers R; Jorm L; Liu B; Vajdic C; Pearson SA, 2024, 'The Medicines Intelligence Data Platform: A Population-Based Data Resource From New South Wales, Australia', Pharmacoepidemiology and Drug Safety, 33, http://dx.doi.org/10.1002/pds.5887

Journal articles | 2023

Brett J; Gillies MB; Buckley NA; Pearson SA; Zoega H, 2023, 'Patterns of suboptimal antipsychotic use and misuse in Australia: What can routinely collected data tell us?', British Journal of Clinical Pharmacology, 89, pp. 3411 - 3420, http://dx.doi.org/10.1111/bcp.15821

Journal articles | 2023

Bruno C; Havard A; Gillies MB; Coghill D; Brett J; Guastella AJ; Pearson SA; Zoega H, 2023, 'Patterns of attention deficit hyperactivity disorder medicine use in the era of new non-stimulant medicines: A population-based study among Australian children and adults (2013–2020)', Australian and New Zealand Journal of Psychiatry, 57, pp. 675 - 685, http://dx.doi.org/10.1177/00048674221114782

Journal articles | 2023

Bruno C; Zoega H; Gillies MB; Havard A; Coghill D; Pearson SA; Brett J, 2023, 'Expanded access to publicly subsidised lisdexamfetamine treatment for adults with attention-deficit/hyperactivity disorder: An interrupted time-series analysis', Australian and New Zealand Journal of Psychiatry, 57, pp. 1073 - 1076, http://dx.doi.org/10.1177/00048674231170556

Journal articles | 2022

Gillies MB; Burgner DP; Ivancic L; Nassar N; Miller JE; Sullivan SG; Todd IMF; Pearson SA; Schaffer AL; Zoega H, 2022, 'Changes in antibiotic prescribing following COVID-19 restrictions: Lessons for post-pandemic antibiotic stewardship', British Journal of Clinical Pharmacology, 88, pp. 1143 - 1151, http://dx.doi.org/10.1111/bcp.15000

Journal articles | 2022

Kusuma K; Larsen M; Quiroz JC; Gillies M; Burnett A; Qian J; Torok M, 2022, 'The performance of machine learning models in predicting suicidal ideation, attempts, and deaths: A meta-analysis and systematic review', Journal of Psychiatric Research, 155, pp. 579 - 588, http://dx.doi.org/10.1016/j.jpsychires.2022.09.050

Journal articles | 2022

Varney B; Zoega H; Gillies MB; Brett J; Pearson SA; Havard A, 2022, 'Prescription opioid use in Australian women of reproductive age: Implications for unplanned pregnancies', British Journal of Clinical Pharmacology, 88, pp. 1298 - 1320, http://dx.doi.org/10.1111/bcp.15074

Journal articles | 2022

Vuong T; Gillies M; Larney S; Montebello M; Ritter A, 2022, 'The association between involuntary alcohol treatment and subsequent emergency department visits and hospitalizations: a Bayesian analysis of treated patients and matched controls', Addiction, 117, pp. 1589 - 1597, http://dx.doi.org/10.1111/add.15755

Journal articles | 2022

de Oliveira Costa J; Gillies MB; Schaffer AL; Peiris D; Zoega H; Pearson SA, 2022, 'Changes in antidepressant use in Australia: A nationwide analysis (2015–2021)', Australian and New Zealand Journal of Psychiatry, 57, http://dx.doi.org/10.1177/00048674221079740

Journal articles | 2018

Gillies MB; Bowen JR; Patterson JA; Roberts CL; Torvaldsen S, 2018, 'Educational outcomes for children with cerebral palsy: a linked data cohort study', Developmental Medicine and Child Neurology, 60, pp. 397 - 401, http://dx.doi.org/10.1111/dmcn.13651

Journal articles | 2016

Gunnell AS; Hung J; Knuiman MW; Nedkoff L; Gillies M; Geelhoed E; Hobbs MST; Katzenellenbogen JM; Rankin JM; Ortiz M; Briffa TG; Sanfilippo FM, 2016, 'Secondary preventive medication use in a prevalent population-based cohort of acute coronary syndrome survivors', Cardiovascular Therapeutics, 34, pp. 423 - 430, http://dx.doi.org/10.1111/1755-5922.12212

Journal articles | 2015

Gillies M; Ranakusuma A; Hoffmann T; Thorning S; McGuire T; Glasziou P; Del C, 2015, 'Common harms from amoxicillin: A systematic review and meta-analysis of randomized placebo-controlled trials for any indication', CMAJ, 187, pp. E21 - E31, http://dx.doi.org/10.1503/cmaj.140848

Journal articles | 2015

Gunnell A; Nedkoff L; Hung J; Knuiman M; Gillies M; Ortiz M; Rankin J; Geelhoed E; Hobbs M; Katzenellenbogen J; Briffa T; Sanfilippo F, 2015, 'Cardioprotective drugs dispensed after admission for myocardial infarction (MI) in a whole population cohort: Western Australian Medication Adherence and Costs in Heart disease study (WAMACH)', Heart, Lung and Circulation, 24, pp. S377 - S378, http://dx.doi.org/10.1016/j.hlc.2015.06.618

Journal articles | 2014

Gillies MB; Williamson M; Merrifield A; Morrell S; Huang N, 2014, 'Surveillance of New Drug Adoption in Australia Using Primary Care EHR Data', PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 23, pp. 133 - 133, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342763600249&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2014

Gunnell AS; Knuiman MW; Geelhoed E; Hobbs MST; Katzenellenbogen JM; Hung J; Rankin JM; Nedkoff L; Briffa TG; Ortiz M; Gillies M; Cordingley A; Messer M; Gardner C; Lopez D; Atkins E; Mai Q; Sanfilippo FM, 2014, 'Long-term use and cost-effectiveness of secondary prevention drugs for heart disease in Western Australian seniors (WAMACH): A study protocol', BMJ Open, 4, http://dx.doi.org/10.1136/bmjopen-2014-006258

Journal articles | 2012

Mulholland S; Gavranich JB; Gillies MB; Chang AB, 2012, 'Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children.', Cochrane Database of Systematic Reviews Online, 9, pp. CD004875

Journal articles | 2011

Gadzhanova S; Gillies M; Roughead E; Zuo Y, 2011, 'Fixed dose combination diabetes medicines: Usage in the Australian veteran population', Australian Family Physician, 40, pp. 811 - 815

Journal articles | 2011

Robertson JG; Moxey AJ; Newby D; Gillies MC; Williamson M; Pearson S, 2011, 'Electronic information and clinical decision support for prescribing: State of play in Australian general practice', Family Practice, 28, pp. 93 - 101, http://dx.doi.org/10.1093/fampra/cmq031

Journal articles | 2009

Gillies MB, 2009, 'NICE: Alone in Europe but not the world', BMJ Online, 338, pp. 428, http://dx.doi.org/10.1136/bmj.b636

Journal articles | 2005

Alonso H; Gillies MB; Cummins PL; Bliznyuk AA; Gready JE, 2005, 'Multiple ligand-binding modes in bacterial R67 dihydrofolate reductase', Journal of Computer Aided Molecular Design, 19, pp. 165 - 187, http://dx.doi.org/10.1007/s10822-005-3693-6

Journal articles | 2003

Gillies MB; Matyjaszewski K; Norrby PO; Pintauer T; Poli R; Richard P, 2003, 'A DFT study of R-X bond dissociation enthalpies of relevance to the initiation process of atom transfer radical polymerization', Macromolecules, 36, pp. 8551 - 8559, http://dx.doi.org/10.1021/ma0351672

Journal articles | 2002

Gillies MB; Tønder JE; Tanner D; Norrby PO, 2002, 'Quantum chemical calculations on the Peterson olefination with α-silyl ester enolates', Journal of Organic Chemistry, 67, pp. 7378 - 7388, http://dx.doi.org/10.1021/jo0262107

Journal articles | 2002

de Mol NJ; Gillies MB; Fischer MJE, 2002, 'Experimental and calculated shift in pKa upon binding of phosphotyrosine peptide to the SH2 domain of p56lck', Bioorganic and Medicinal Chemistry, 10, pp. 1477 - 1482, http://dx.doi.org/10.1016/S0968-0896(01)00407-2

Journal articles | 1999

Moret EE; Van Wijk MC; Kostense AS; Gillies MB, 1999, 'Scoring peptide(mimetic)-protein interactions', Medicinal Chemistry Research, 9, pp. 604 - 620
Preprints | 2025

Varney B; Zoega H; Gillies MB; Bruno C; Havard A; Shand AW; Nassar N; Brett J, 2025, Prenatal prescription opioid analgesic exposure and academic performance in third grade children: An Australian population-based cohort study, http://dx.doi.org/10.22541/au.175533129.98373096/v1

Conference Papers | 2024

Araki M; Zoega H; Gillies MB; Falster M; Peiris D; Larsson H; Costa JDO, 2024, 'Cardiovascular Medicine Use in Adults with ADHD: A Nationwide Study in Australia', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, pp. 130 - 131

Conference Presentations | 2024

Bharat C; Gisev N; Hopkins R; Pearson SA; Gillies M; Dobbins T; Larney S; Blythe F; Degenhardt L, 2024, 'Development of opioid use disorder following treatment with opioid analgesics for non-cancer pain relief: an Australian state-wide nested case-control study', presented at 2024 NDARC Annual Research Symposium, Wesley Conference Centre, Sydney NSW, 20 September 2024, https://www.youtube.com/watch?v=SwVO9ONBuE8&t=5295s

Conference Papers | 2024

Bharat C; Stehlik P; Camacho X; Chidwick K; Daniels B; Gillies MB; Hansford H; Ho JN; Lin J; Lopez D; Kelly T-L; Kelty E; Noghrehchi F; Varney B; Filion KB; Pratt N, 2024, 'The Use and Implementation of Instrumental Variables in Pharmacoepidemiology: A Scoping Review', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, pp. 618 - 618

Conference Posters | 2024

Chidwick K, 2024, 'Long-term prescribed opioid use after hospitalisation or emergency department presentation among opioid-naïve adults in New South Wales (NSW), Australia (2014–2020)—a population-based cohort study', Wesley Conference Centre, Sydney NSW, presented at 2024 NDARC Annual Research Symposium, Wesley Conference Centre, Sydney NSW, 20 September 2024

Conference Papers | 2024

Gillies MB; Bharat C; Camacho X; Daniels B; Hall K; Kelly T-L; Kelty E; Lin J; Litchfield M; Lopez D; Noghrehchi F; Raubenhimer J; Varney B; Pratt N, 2024, 'Medicine Utilisation Studies in Australian Individual-Level Dispensing data: A blinded, Multi-Centre Replication Experiment', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, pp. 241 - 241

Preprints | 2024

Sit A; Bruno C; Araki M; Gillies M; Zoega H, 2024, Attention-deficit/hyperactivity disorder medication use and cardiometabolic conditions in pregnancy: A population-based cohort study, http://dx.doi.org/10.22541/au.172742419.94824081/v1

Conference Papers | 2024

Yao H; Xie T; Gillies MB; Hartman C; Chang Z, 2024, 'The Relationships Between ADHD/ADHD Medication and the Persistence of Anti-Hypertensive Medication?', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, pp. 515 - 515

Preprints | 2024

Zoega H; Falster M; Gillies M; Litchfield M; Camacho X; Bruno C; Daniels B; Donnolley N; Havard A; Schaffer A; Chambers G; Degenhardt L; Dobbins T; Gisev N; Ivers R; Jorm L; Liu B; Vajdic C; Pearson S-A, 2024, The Medicines Intelligence Data Platform: A population-based data resource from New South Wales, Australia, http://dx.doi.org/10.1101/2024.04.29.24306520

Conference Papers | 2023

Bruno C; Cesta CE; Hjellvik V; Ulrichsen SP; Bjork M-HH; Esen BO; Gillies MB; Gissler M; Havard A; Karlsson P; Karlstad O; Leinonen MK; Norgaard M; Pearson S-A; Reutfors J; Stigum H; Furu K; Cohen J; Zoega H, 2023, 'Prenatal exposure to antipsychotic medication and neurocognitive impairment among children: A Nordic cohort study', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, pp. 616 - 617

Conference Abstracts | 2022

Bruno C; Havard A; Gillies M; Coghill D; Brett J; Guastella A; Pearson S-A; Zoega H, 2022, 'Patterns of ADHD medicine use: A population-based study among Australian children and adults (2013-2020)', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, Vol. 31, pp. 71 - 71, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000859084400136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints | 2021

de Oliveira Costa J; Gillies M; Schaffer A; Peiris D; Zoega H; Pearson S-A, 2021, Changes in antidepressant use in Australia: A nationwide analysis prior to and during the COVID-19 pandemic (2015-2021), http://dx.doi.org/10.1101/2021.11.24.21266837

Conference Papers | 2014

Huang N; Hains I; London J; Delaney C; Williamson M; Gillies MB; Marshall C, 2014, 'We've Got Your Clinical Data - What's in It for Clinicians?', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY-BLACKWELL, pp. 479 - 479

Conference Presentations | 2013

Gillies MB; Galgani F; Tsafnat G; Dunn AG; Huang N; Williamson M, 2013, 'Feasibility of Using Australian GP Prescribing Data for Pharmacovigilance', presented at 29th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Montreal, Canada, 25 August 2013 - 28 August 2013

Executive member NSW Population & Health Services Research Ethics Committee

My Research Supervision

Kate Maston, Black Dog Institute (secondary supervisor)

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