Ms Mariana Ruiz Silva
Research Associate

Ms Mariana Ruiz Silva

BSc, MSc, PhD

Medicine & Health
The Kirby Institute

Mariana graduated in Pharmaceutical and Biological Chemistry from the Universidad Nacional Autonoma de Mexico. She holds a MSc in Medical and Pharmaceutical Drug Innovation from the Rijksuniversiteit Groningen (RUG) in The Netherlands. She received a PhD in virology from the RUG for the study of the innate immune response to dengue and chikungunya virus (co)-infections. After moving to Australia, she worked as a research assistant for NSW Health and UNSW performing whole genome sequencing of SARS-CoV-2. In 2021, Mariana joined the Kirby Institute to investigate the pathogenesis of SARS-CoV-2. She has experience working with viruses in a Biosafety level 3 lab, TIRF microscopy and next-generation sequencing.  

Level 5, Wallace Wurth Building, UNSW Sydney NSW 2052
  • Journal articles | 2022
    Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Stella AO; Kindinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Jean T; Foster CSP; Christ D; Hoppe AC; Munier ML; Darley D; Churchill M; Stark DJ; Matthews G; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern.', EBioMedicine, vol. 84, pp. 104270,
    Journal articles | 2022
    Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, vol. 7, pp. 896 - 908,
    Journal articles | 2022
    Foster CSP; Stelzer-Braid S; Deveson IW; Bull RA; Yeang M; Au JP; Ruiz Silva M; van Hal SJ; Rockett RJ; Sintchenko V; Kim KW; Rawlinson WD, 2022, 'Assessment of Inter-Laboratory Differences in SARS-CoV-2 Consensus Genome Assemblies between Public Health Laboratories in Australia', Viruses, vol. 14, pp. 185 - 185,
    Journal articles | 2020
    Aguilar-Briseño JA; Upasani V; Ellen BMT; Moser J; Pauzuolis M; Ruiz-Silva M; Heng S; Laurent D; Choeung R; Dussart P; Cantaert T; Smit JM; Rodenhuis-Zybert IA, 2020, 'TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis', Nature Communications, vol. 11,
    Journal articles | 2017
    Ruiz Silva M; Aguilar Briseño JA; Upasani V; van der Ende-Metselaar H; Smit JM; Rodenhuis-Zybert IA, 2017, 'Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus', PLoS Neglected Tropical Diseases, vol. 11,
    Journal articles | 2016
    Ruiz Silva M; Van Der Ende-Metselaar H; Mulder HL; Smit JM; Rodenhuis-Zybert IA, 2016, 'Mechanism and role of MCP-1 upregulation upon chikungunya virus infection in human peripheral blood mononuclear cells', Scientific Reports, vol. 6,
    Journal articles | 2014
    Rüter C; Silva MR; Grabowski B; Lubos ML; Scharnert J; Poceva M; von Tils D; Flieger A; Heesemann J; Bliska JB; Schmidt MA, 2014, 'Rabbit monoclonal antibodies directed at the T3SS effector protein YopM identify human pathogenic Yersinia isolates', International Journal of Medical Microbiology, vol. 304, pp. 444 - 451,
    Journal articles | 2012
    Van Der Goot AT; Zhu W; Vázquez-Manrique RP; Seinstra RI; Dettmer K; Michels H; Farina F; Krijnen J; Melki R; Buijsman RC; Silva MR; Thijssen KL; Kema IP; Neri C; Oefner PJ; Nollen EAA, 2012, 'Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. 14912 - 14917,
  • Preprints | 2022
    Aggarwal A; Stella A; Akerman A; Walker G; Milogiannakis V; McAllery S; Esneau C; Silva MR; Lu Y; Forster C; Hal SV; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Darley D; Matthews G; Starck D; Robosa R; Bartlett N; Rawlinson W; Kelleher A; Turville S, 2022, Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants,
    Preprints | 2020
    Aguilar-Briseño JA; Silva MR; Moser J; Pauzuolis M; Smit J; Rodenhuis-Zybert I, 2020, Rewiring PBMC responses to prevent CHIKV infection-specific monocyte subset redistribution and cytokine responses,

2016 Jan Kornelis de Cock Foundation Grant

2010 Mexican National Council for Science and Technology (CONACyT) Scholarship

2010 Medical and Pharmaceutical Drug Innovation (MPDI) Scholarship

SARS-CoV-2 pathogenesis