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Ms Mariana Ruiz Silva

Ms Mariana Ruiz Silva

Research Associate

BSc, MSc, PhD

Medicine & Health
The Kirby Institute

Mariana graduated in Pharmaceutical and Biological Chemistry from the Universidad Nacional Autonoma de Mexico. She holds a MSc in Medical and Pharmaceutical Drug Innovation from the Rijksuniversiteit Groningen (RUG) in The Netherlands. She received a PhD in virology from the RUG for the study of the innate immune response to dengue and chikungunya virus (co)-infections. After moving to Australia, she worked as a research assistant for NSW Health and UNSW performing whole genome sequencing of SARS-CoV-2. In 2021, Mariana joined the Kirby Institute to investigate the pathogenesis of SARS-CoV-2. She has experience working with viruses in a Biosafety level 3 lab, TIRF microscopy and next-generation sequencing.  
Phone
+61-2-93480776
E-mail
mruizsilva@kirby.unsw.edu.au
Location
Level 5, Wallace Wurth Building, UNSW Sydney NSW 2052
  • Journal articles | 2023
    Akerman A; Milogiannakis V; Jean T; Esneau C; Silva MR; Ison T; Fichter C; Lopez JA; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster CSP; Sato K; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Britton W; Sandgren K; Bull R; Lloyd A; Triccas J; Tangye S; Bartlett NW; Darley D; Matthews G; Stark DJ; Petoumenos K; Rawlinson WD; Murrell B; Brilot F; Cunningham AL; Kelleher AD; Aggarwal A; Turville SG, 2023, 'Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level', eBioMedicine, 90, http://dx.doi.org/10.1016/j.ebiom.2023.104545
    Journal articles | 2022
    Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Stella AO; Kindinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Jean T; Foster CSP; Christ D; Hoppe AC; Munier ML; Darley D; Churchill M; Stark DJ; Matthews G; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern', eBioMedicine, 84, http://dx.doi.org/10.1016/j.ebiom.2022.104270
    Journal articles | 2022
    Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, 7, pp. 896 - 908, http://dx.doi.org/10.1038/s41564-022-01135-7
    Journal articles | 2022
    Foster CSP; Stelzer-Braid S; Deveson IW; Bull RA; Yeang M; Au JP; Ruiz Silva M; van Hal SJ; Rockett RJ; Sintchenko V; Kim KW; Rawlinson WD, 2022, 'Assessment of Inter-Laboratory Differences in SARS-CoV-2 Consensus Genome Assemblies between Public Health Laboratories in Australia', Viruses, 14, http://dx.doi.org/10.3390/v14020185
    Journal articles | 2020
    Aguilar-Briseño JA; Upasani V; Ellen BMT; Moser J; Pauzuolis M; Ruiz-Silva M; Heng S; Laurent D; Choeung R; Dussart P; Cantaert T; Smit JM; Rodenhuis-Zybert IA, 2020, 'TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-16849-7
    Journal articles | 2017
    Ruiz Silva M; Aguilar Briseño JA; Upasani V; van der Ende-Metselaar H; Smit JM; Rodenhuis-Zybert IA, 2017, 'Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus', PLoS Neglected Tropical Diseases, 11, http://dx.doi.org/10.1371/journal.pntd.0005712
    Journal articles | 2016
    Ruiz Silva M; Van Der Ende-Metselaar H; Mulder HL; Smit JM; Rodenhuis-Zybert IA, 2016, 'Mechanism and role of MCP-1 upregulation upon chikungunya virus infection in human peripheral blood mononuclear cells', Scientific Reports, 6, http://dx.doi.org/10.1038/srep32288
    Journal articles | 2014
    Rüter C; Silva MR; Grabowski B; Lubos ML; Scharnert J; Poceva M; von Tils D; Flieger A; Heesemann J; Bliska JB; Schmidt MA, 2014, 'Rabbit monoclonal antibodies directed at the T3SS effector protein YopM identify human pathogenic Yersinia isolates', International Journal of Medical Microbiology, 304, pp. 444 - 451, http://dx.doi.org/10.1016/j.ijmm.2014.02.003
    Journal articles | 2012
    Van Der Goot AT; Zhu W; Vázquez-Manrique RP; Seinstra RI; Dettmer K; Michels H; Farina F; Krijnen J; Melki R; Buijsman RC; Silva MR; Thijssen KL; Kema IP; Neri C; Oefner PJ; Nollen EAA, 2012, 'Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation', Proceedings of the National Academy of Sciences of the United States of America, 109, pp. 14912 - 14917, http://dx.doi.org/10.1073/pnas.1203083109
  • Preprints | 2022
    Aggarwal A; Stella A; Akerman A; Walker G; Milogiannakis V; McAllery S; Esneau C; Silva MR; Lu Y; Forster C; Hal SV; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Darley D; Matthews G; Starck D; Robosa R; Bartlett N; Rawlinson W; Kelleher A; Turville S, 2022, Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants, http://dx.doi.org/10.21203/rs.3.rs-1210846/v1
    Preprints | 2020
    Aguilar-Briseño JA; Silva MR; Moser J; Pauzuolis M; Smit J; Rodenhuis-Zybert I, 2020, Rewiring PBMC responses to prevent CHIKV infection-specific monocyte subset redistribution and cytokine responses, , http://dx.doi.org/10.1101/2020.06.04.132340

2016 Jan Kornelis de Cock Foundation Grant

2010 Mexican National Council for Science and Technology (CONACyT) Scholarship

2010 Medical and Pharmaceutical Drug Innovation (MPDI) Scholarship

SARS-CoV-2 pathogenesis