Conjoint Senior Lecturer

Dr Mark Pinese

BAdvSc (Hons.), PhD

medicine-health
Sch Women's&Children's Health

Dr Pinese completed his undergraduate studies at UNSW Australia on the biology of ageing, before moving to the Garvan Institute to pursue cancer research. 

At the Garvan Institute, Dr Pinese was a member of the world's largest sequencing effort in pancreatic cancer, and for his work received a PhD on the molecular determinants of survival of patients with pancreatic adenocarcinoma.  Dr Pinese then joined the Kinghorn Centre for Clinical Genomics, where he performed rapid-turnaround genomic analysis for cancer patients, and helped to develop Australia's first clinically-accredited whole genome sequencing test for rare disease. 

Dr Pinese is currently a Senior Research Officer in Garvan's Genomic Cancer Medicine Lab, where he is the lead analyst for the Medical Genome Reference Bank, and conducts research into the genetic basis of cancer risk.

Location
Kinghorn Cancer Centre 370 Victoria St Darlinghurst NSW 2010

Publications

  • Journal articles | 2021
    Dr Mark Pinese
    Dreyer SB; Upstill-Goddard R; Paulus-Hock V; Paris C; Lampraki EM; Dray E; Serrels B; Caligiuri G; Rebus S; Plenker D; Galluzzo Z; Brunton H; Cunningham R; Tesson M; Nourse C; Bailey UM; Jones MD; Moran-Jones K; Wright DW; Duthie F; Oien K; Evers L; McKay CJ; McGregor GA; Gulati A; Brough R; Bajrami I; Pettitt S; Dziubinski ML; Candido J; Balkwill F; Barry ST; Grützmann R; Rahib L; Allison S; Bailey PJ; Biankin AV; Beraldi D; Cameron E; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; Martin S; McDade B; McElroy D; Musgrove EA; Ramsay D; Wright D; Hair J; Jamieson NB; Westwood P; Williams N; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C, 2021, 'Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer', Gastroenterology, vol. 160, pp. 362 - 377.e13, http://dx.doi.org/10.1053/j.gastro.2020.09.043
    Journal articles | 2021
    Dr Mark Pinese
    Minoche AE; Lundie B; Peters GB; Ohnesorg T; Pinese M; Thomas DM; Zankl A; Roscioli T; Schonrock N; Kummerfeld S; Burnett L; Dinger ME; Cowley MJ, 2021, 'ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data', Genome Medicine, vol. 13, http://dx.doi.org/10.1186/s13073-021-00841-x
    Journal articles | 2020
    Dr Mark Pinese
    Brunton H; Caligiuri G; Cunningham R; Upstill-Goddard R; Bailey UM; Garner IM; Nourse C; Dreyer S; Jones M; Moran-Jones K; Wright DW; Paulus-Hock V; Nixon C; Thomson G; Jamieson NB; McGregor GA; Evers L; McKay CJ; Gulati A; Brough R; Bajrami I; Pettitt SJ; Dziubinski ML; Barry ST; Grützmann R; Brown R; Curry E; Allison S; Biankin AV; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; McDade B; McElroy D; Ramsay D; Rebus S; Hair J; Westwood P; Williams N; Duthie F; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Newell F; Pearson JV; Quinn M, 2020, 'HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer', Cell Reports, vol. 31, http://dx.doi.org/10.1016/j.celrep.2020.107625
    Journal articles | 2020
    Dr Mark Pinese
    Li CH; Prokopec SD; Sun RX; Yousif F; Schmitz N; Al-Shahrour F; Atwal G; Bailey PJ; Biankin AV; Boutros PC; Campbell PJ; Chang DK; Cooke SL; Deshpande V; Faltas BM; Faquin WC; Garraway L; Getz G; Grimmond SM; Haider S; Hoadley KA; Jiao W; Kaiser VB; Karlić R; Kato M; Kübler K; Lazar AJ; Li CH; Louis DN; Margolin A; Martin S; Nahal-Bose HK; Nielsen GP; Nik-Zainal S; Omberg L; P’ng C; Perry MD; Polak P; Rheinbay E; Rubin MA; Semple CA; Sgroi DC; Shibata T; Siebert R; Smith J; Stein LD; Stobbe MD; Sun RX; Thai K; Wright DW; Wu CL; Yuan K; Zhang J; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A, 2020, 'Sex differences in oncogenic mutational processes', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-17359-2
    Journal articles | 2020
    Dr Mark Pinese
    Dreyer SB; Pinese M; Jamieson NB; Scarlett CJ; Colvin EK; Pajic M; Johns AL; Humphris JL; Wu J; Cowley MJ; Chou A; Nagrial AM; Chantrill L; Chin VT; Jones MD; Moran-Jones K; Carter CR; Dickson EJ; Samra JS; Merrett ND; Gill AJ; Kench JG; Duthie F; Miller DK; Cooke S; Aust D; Knösel T; Rümmele P; Grützmann R; Pilarsky C; Nguyen NQ; Musgrove EA; Bailey PJ; McKay CJ; Biankin AV; Chang DK, 2020, 'Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer', Annals of surgery, vol. 272, pp. 366 - 376, http://dx.doi.org/10.1097/SLA.0000000000003143
    Journal articles | 2020
    Dr Mark Pinese
    Campbell PJ; Getz G; Korbel JO; Stuart JM; Jennings JL; Stein LD; Perry MD; Nahal-Bose HK; Ouellette BFF; Li CH; Rheinbay E; Nielsen GP; Sgroi DC; Wu CL; Faquin WC; Deshpande V; Boutros PC; Lazar AJ; Hoadley KA; Louis DN; Dursi LJ; Yung CK; Bailey MH; Saksena G; Raine KM; Buchhalter I; Kleinheinz K; Schlesner M; Zhang J; Wang W; Wheeler DA; Ding L; Simpson JT; O’Connor BD; Yakneen S; Ellrott K; Miyoshi N; Butler AP; Royo R; Shorser SI; Vazquez M; Rausch T; Tiao G; Waszak SM; Rodriguez-Martin B; Shringarpure S; Wu DY; Demidov GM; Delaneau O; Hayashi S; Imoto S; Habermann N; Segre AV; Garrison E; Cafferkey A; Alvarez EG; Heredia-Genestar JM; Muyas F; Drechsel O; Bruzos AL; Temes J; Zamora J; Baez-Ortega A; Kim HL; Mashl RJ; Ye K; DiBiase A; Huang KL; Letunic I; McLellan MD; Newhouse SJ; Shmaya T; Kumar S; Wedge DC; Wright MH; Yellapantula VD; Gerstein M; Khurana E; Marques-Bonet T; Navarro A; Bustamante CD; Siebert R; Nakagawa H; Easton DF; Ossowski S; Tubio JMC; De La Vega FM; Estivill X; Yuen D; Mihaiescu GL; Omberg L; Ferretti V; Sabarinathan R; Pich O; Gonzalez-Perez A; Taylor-Weiner A; Fittall MW; Demeulemeester J; Tarabichi M; Roberts ND, 2020, 'Pan-cancer analysis of whole genomes', Nature, vol. 578, pp. 82 - 93, http://dx.doi.org/10.1038/s41586-020-1969-6
    Journal articles | 2020
    Dr Mark Pinese
    Bailey MH; Meyerson WU; Dursi LJ; Wang LB; Dong G; Liang WW; Weerasinghe A; Li S; Li Y; Kelso S; Akbani R; Anur P; Bailey MH; Buchanan A; Chiotti K; Covington K; Creason A; Ding L; Ellrott K; Fan Y; Foltz S; Getz G; Hale W; Haussler D; Hess JM; Hutter CM; Kandoth C; Kasaian K; Kasapi M; Larson D; Leshchiner I; Letaw J; Ma S; McLellan MD; Men Y; Mills GB; Niu B; Peto M; Radenbaugh A; Reynolds SM; Saksena G; Sofia H; Stewart C; Struck AJ; Stuart JM; Wang W; Weinstein JN; Wheeler DA; Wong CK; Xi L; Ye K; Bailey MH; Niu B; Bieg M; Boutros PC; Buchhalter I; Butler AP; Chen K; Chong Z; Ding L; Drechsel O; Jonathan Dursi L; Eils R; Ellrott K; Espiritu SMG; Fan Y; Fulton RS; Gao S; Gelpi JLL; Gerstein MB; Gonzalez S; Gut IG; Hach F; Heinold MC; Hess JM; Hinton J; Hu T; Huang V; Huang Y; Hutter B; Jones DR; Jung J; Jäger N; Kim HL; Kleinheinz K; Kumar S; Kumar Y; Lalansingh CM; Letunic I; Livitz D; Ma EZ; Maruvka YE; Mashl RJ; McLellan MD; Menzies A; Milovanovic A; Nielsen MM; Ossowski S, 2020, 'Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-20128-w
    Journal articles | 2020
    Dr Mark Pinese
    Bailey MH; Meyerson WU; Dursi LJ; Wang LB; Dong G; Liang WW; Weerasinghe A; Li S; Kelso S; Akbani R; Anur P; Bailey MH; Buchanan A; Chiotti K; Covington K; Creason A; Ding L; Ellrott K; Fan Y; Foltz S; Getz G; Hale W; Haussler D; Hess JM; Hutter CM; Kandoth C; Kasaian K; Kasapi M; Larson D; Leshchiner I; Letaw J; Ma S; McLellan MD; Men Y; Mills GB; Niu B; Peto M; Radenbaugh A; Reynolds SM; Saksena G; Sofia H; Stewart C; Struck AJ; Stuart JM; Wang W; Weinstein JN; Wheeler DA; Wong CK; Xi L; Ye K; Bailey MH; Niu B; Bieg M; Boutros PC; Buchhalter I; Butler AP; Chen K; Chong Z; Ding L; Drechsel O; Jonathan Dursi L; Eils R; Ellrott K; Espiritu SMG; Fan Y; Fulton RS; Gao S; Gelpi JLL; Gerstein MB; Gonzalez S; Gut IG; Hach F; Heinold MC; Hess JM; Hinton J; Hu T; Huang V; Huang Y; Hutter B; Jones DR; Jung J; Jäger N; Kim HL; Kleinheinz K; Kumar S; Kumar Y; Lalansingh CM; Letunic I; Livitz D; Ma EZ; Maruvka YE; Mashl RJ; McLellan MD; Menzies A; Milovanovic A; Nielsen MM; Ossowski S; Paramasivam N, 2020, 'Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-18151-y
    Journal articles | 2020
    Dr Mark Pinese
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Dr Mark Pinese
    Pinese M; Lacaze P; Rath EM; Stone A; Brion MJ; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Cristina TN; Kahl VFS; Statham AL; Woods RL; McNeil JJ; Riaz M; Barr M; Nelson MR; Reid CM; Murray AM; Shah RC; Wolfe R; Atkins JR; Fitzsimmons C; Cairns HM; Green MJ; Carr VJ; Cowley MJ; Pickett HA; James PA; Powell JE; Kaplan W; Gibson G; Gyllensten U; Cairns MJ; McNamara M; Dinger ME; Thomas DM, 2020, 'The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-019-14079-0
    Journal articles | 2020
    Dr Mark Pinese
    Khuong-Quang DA; Brown LM; Wong M; Mayoh C; Sexton-Oates A; Kumar A; Pinese M; Nagabushan S; Lau L; Ludlow LE; Gifford AJ; Rodriguez M; Desai J; Fox SB; Haber M; Ziegler DS; Hansford JR; Marshall GM; Cowley MJ; Ekert PG, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, vol. 6, http://dx.doi.org/10.1101/MCS.A005710
    Journal articles | 2019
    Dr Mark Pinese
    McCabe MJ; Pinese M; Chan CL; Sheriff N; Thompson TJ; Grady J; Wong M; Gauthier MEA; Puttick C; Gayevskiy V; Hajdu E; Wong SQ; Barrett W; Earls P; Lukeis R; Cheng YY; Lin RCY; Thomas DM; Watkins DN; Dinger ME; McCormack AI; Cowley MJ, 2019, 'Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases', Cold Spring Harbor Molecular Case Studies, vol. 5, http://dx.doi.org/10.1101/mcs.a003764
    Journal articles | 2019
    Dr Mark Pinese
    Vennin C; Mélénec P; Rouet R; Nobis M; Cazet AS; Murphy KJ; Herrmann D; Reed DA; Lucas MC; Warren SC; Elgundi Z; Pinese M; Kalna G; Roden D; Samuel M; Zaratzian A; Grey ST; Da Silva A; Leung W; Johns AL; Chantrill LA; Chou A; Steinmann A; Arshi M; Dwarte T; Froio D; Pereira B; Ritchie S; Chambers CR; Metcalf X; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Christ A; Bruxner T; Samra JS; Pavlakis N; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Cooper CL; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Zeps N; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C, 2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, vol. 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6
    Journal articles | 2019
    Dr Mark Pinese
    Lacaze P; Pinese M; Kaplan W; Stone A; Brion MJ; Woods RL; McNamara M; McNeil JJ; Dinger ME; Thomas DM, 2019, 'The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design', European Journal of Human Genetics, vol. 27, pp. 308 - 316, http://dx.doi.org/10.1038/s41431-018-0279-z
    Journal articles | 2019
    Dr Mark Pinese
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Therapeutic implications of germline genetic findings in cancer', Nature Reviews Clinical Oncology, vol. 16, pp. 386 - 396, http://dx.doi.org/10.1038/s41571-019-0179-3
    Journal articles | 2019
    Dr Mark Pinese
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Author Correction: Therapeutic implications of germline genetic findings in cancer (Nature Reviews Clinical Oncology, (2019), 16, 6, (386-396), 10.1038/s41571-019-0179-3)', Nature Reviews Clinical Oncology, vol. 16, pp. 397, http://dx.doi.org/10.1038/s41571-019-0212-6
    Journal articles | 2019
    Dr Mark Pinese
    Jones RM; Melton PE; Pinese M; Rea AJ; Ingley E; Ballinger ML; Wood DJ; Thomas DM; Moses EK, 2019, 'Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts', BMC Medical Genetics, vol. 20, http://dx.doi.org/10.1186/s12881-019-0808-9
    Journal articles | 2019
    Dr Mark Pinese
    Puttick C; Kumar K; Davis R; Pinese M; Thomas D; Dinger M; Sue C; Cowley M, 2019, 'mity: A highly sensitive mitochondrial variant analysis pipeline for whole genome sequencing data', , http://dx.doi.org/10.1101/852210
    Journal articles | 2018
    Dr Mark Pinese
    Rath EM; Cheng YY; Pinese M; Sarun KH; Hudson AL; Weir C; Wang YD; Håkansson AP; Howell VM; Liu GJ; Reid G; Knott RB; Duff AP; Bret Church W, 2018, 'BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state', PLoS ONE, vol. 13, http://dx.doi.org/10.1371/journal.pone.0203003
    Journal articles | 2018
    Dr Mark Pinese
    Mladenova D; Barry G; Konen LM; Pineda SS; Guennewig B; Avesson L; Zinn R; Schonrock N; Bitar M; Jonkhout N; Crumlish L; Kaczorowski DC; Gong A; Pinese M; Franco GR; Walkley CR; Vissel B; Mattick JS, 2018, 'Adar3 is involved in learning and memory in mice', Frontiers in Neuroscience, vol. 12, http://dx.doi.org/10.3389/fnins.2018.00243
    Journal articles | 2018
    Dr Mark Pinese
    Chou A; Froio D; Nagrial AM; Parkin A; Murphy KJ; Chin VT; Wohl D; Steinmann A; Stark R; Drury A; Walters SN; Vennin C; Burgess A; Pinese M; Chantrill LA; Cowley MJ; Molloy TJ; Waddell N; Johns A; Grimmond SM; Chang DK; Biankin AV; Sansom OJ; Morton JP; Grey ST; Cox TR; Turchini J; Samra J; Clarke SJ; Timpson P; Gill AJ; Pajic M, 2018, 'Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer', Gut, vol. 67, pp. 2142 - 2155, http://dx.doi.org/10.1136/gutjnl-2017-315144
    Journal articles | 2018
    Dr Mark Pinese
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, vol. 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
    Journal articles | 2018
    Dr Mark Pinese
    Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M, 2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, vol. 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
    Journal articles | 2018
    Dr Mark Pinese
    Conway JRW; Warren SC; Herrmann D; Murphy KJ; Cazet AS; Vennin C; Shearer RF; Killen MJ; Magenau A; Mélénec P; Pinese M; Nobis M; Zaratzian A; Boulghourjian A; Da Silva AM; del Monte-Nieto G; Adam ASA; Harvey RP; Haigh JJ; Wang Y; Croucher DR; Sansom OJ; Pajic M; Caldon CE; Morton JP; Timpson P, 2018, 'Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer', Cell Reports, vol. 23, pp. 3312 - 3326, http://dx.doi.org/10.1016/j.celrep.2018.05.038
    Journal articles | 2018
    Dr Mark Pinese
    Dreyer S; Pinese M; Jamieson N; Upstill-Goddard R; Duthie F; McKay C; Biankin A; Chang D, 2018, '10. Precision Oncology in Surgery: Patient Selection Biomarkers for Operable Pancreatic Cancer', European Journal of Surgical Oncology, vol. 44, pp. 1838 - 1838, http://dx.doi.org/10.1016/j.ejso.2018.10.024
    Journal articles | 2018
    Dr Mark Pinese
    Pinese M; Lacaze P; Rath E; Stone A; Brion M-J; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Navin Cristina T; Silva Kahl V; Statham A; Woods R; McNeil J; Riaz M; Barr M; Nelson M; Reid C; Murray A; Shah R; Wolfe R; Atkins J; Fitzsimmons C; Cairns H; Green M; Carr V; Cowley M; Pickett H; James P; Powell J; Kaplan W; Gibson G; Gyllensten U; Cairns M; McNamara M; Dinger M; Thomas D, 2018, 'The Medical Genome Reference Bank: Whole genomes and phenotype of 2,570 healthy elderly', bioRxiv, http://dx.doi.org/10.1101/473348
    Journal articles | 2018
    Dr Mark Pinese
    Pattnaik S; Vacher C; Lee HC; Kaplan W; Thomas D; Wu J; Pinese M, 2018, 'Network-aware mutation clustering of cancer', BIORXIV, http://dx.doi.org/10.1101/432872
    Journal articles | 2017
    Dr Mark Pinese
    Johns AL; McKay SH; Humphris JL; Pinese M; Chantrill LA; Mead RS; Tucker K; Andrews L; Goodwin A; Leonard C; High HA; Nones K; Waddell N; Patch AM; Merrett ND; Pavlakis N; Kassahn KS; Samra JS; Miller DK; Chang DK; Pajic M; Pearson JV; Grimmond SM; Zeps N; Gill AJ; Biankin AV; Chin VT; Chou A; Steinmann A; Arshi M; Drury A; Froio D; Morgan A; Timpson P; Hermann D; Vennin C; Warren S; Wu J; Pinho AV; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Wood S; Xu C; Hofmann O; Wilson PJ; Christ A; Bruxner T; Samra S; Arena J; Mittal A; Asghari R; Pavey D; Das A; Cosman PH; Ismail K; O'Connnor C; Williams D; Spigellman A; Lam W; McLeod D; Nagrial AM; Kirk J; James V; Grimison P; Cooper CL; Sandroussi C; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Brooke-Smith ME; Papangelis V; Clouston AD; Martin P; Barbour AP; O'Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Hruban RH; Wolfgang CL; Hodgin M; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C; Bailey P; Martin S; Musgrove EA, 2017, 'Lost in translation: Returning germline genetic results in genome-scale cancer research', Genome Medicine, vol. 9, http://dx.doi.org/10.1186/s13073-017-0430-4
    Journal articles | 2017
    Dr Mark Pinese
    Scarpa A; Chang DK; Nones K; Corbo V; Patch AM; Bailey P; Lawlor RT; Johns AL; Miller DK; Mafficini A; Rusev B; Scardoni M; Antonello D; Barbi S; Sikora KO; Cingarlini S; Vicentini C; McKay S; Quinn MCJ; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; McLean S; Nourse C; Nourbakhsh E; Wilson PJ; Anderson MJ; Fink JL; Newell F; Waddell N; Holmes O; Kazakoff SH; Leonard C; Wood S; Xu Q; Nagaraj SH; Amato E; Dalai I; Bersani S; Cataldo I; Dei Tos AP; Capelli P; Davì MV; Landoni L; Malpaga A; Miotto M; Whitehall VLJ; Leggett BA; Harris JL; Harris J; Jones MD; Humphris J; Chantrill LA; Chin V; Nagrial AM; Pajic M; Scarlett CJ; Pinho A; Rooman I; Toon C; Wu J; Pinese M; Cowley M; Barbour A; Mawson A; Humphrey ES; Colvin EK; Chou A; Lovell JA; Jamieson NB; Duthie F; Gingras MC; Fisher WE; Dagg RA; Lau LMS; Lee M; Pickett HA; Reddel RR; Samra JS; Kench JG; Merrett ND; Epari K; Nguyen NQ; Zeps N; Falconi M; Simbolo M; Butturini G; Van Buren G; Partelli S; Fassan M; Khanna KK; Gill AJ; Wheeler DA; Gibbs RA; Musgrove EA; Bassi C; Tortora G; Pederzoli P; Pearson JV, 2017, 'Whole-genome landscape of pancreatic neuroendocrine tumours', Nature, vol. 543, pp. 65 - 71, http://dx.doi.org/10.1038/nature21063
    Journal articles | 2017
    Dr Mark Pinese
    Humphris JL; Patch AM; Nones K; Bailey PJ; Johns AL; McKay S; Chang DK; Miller DK; Pajic M; Kassahn KS; Quinn MCJ; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; Manning S; Nourse C; Nourbakhsh E; Stone A; Wilson PJ; Anderson M; Fink JL; Holmes O; Kazakoff S; Leonard C; Newell F; Waddell N; Wood S; Mead RS; Xu Q; Wu J; Pinese M; Cowley MJ; Jones MD; Nagrial AM; Chin VT; Chantrill LA; Mawson A; Chou A, 2017, 'Hypermutation In Pancreatic Cancer', Gastroenterology, vol. 152, pp. 68 - 74.e2, http://dx.doi.org/10.1053/j.gastro.2016.09.060
    Journal articles | 2017
    Dr Mark Pinese
    Scarpa A; Hang DKC; Nones K; Corbo V; Patch A-M; Bailey P; Lawlor RT; Johns AL; Miller DK; Mafficini A; Rusev B; Scardoni M; Antonello D; Barbi S; Sikora KO; Cingarlini S; Vicentini C; McKay S; Quinn MCJ; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; McLean S; Nourse C; Nourbakhsh E; Wilson PJ; Anderson MJ; Fink JL; Newell F; Waddell N; Holmes O; Kazakoff SH; Leonard C; Wood S; Xu Q; Nagaraj SH; Amato E; Dalai I; Bersani S; Cataldo I; Tos APD; Capelli P; Davi MV; Landoni L; Malpaga A; Miotto M; Whitehall VLJ; Leggett BA; Harris JL; Harris J; Jones MD; Humphris J; Hantrill LAC; Chin V; Nagrial AM; Pajic M; Scarlett CJ; Pinho A; Rooman I; Toon C; Wu J; Pinese M; Cowley M; Barbour A; Mawson A; Humphrey ES; Colvin EK; Chou A; Lovell JA; Jamieson NB; Duthie F; Gingras M-C; Fisher WE; Dagg RA; Lau LMS; Lee M; Pickett HA; Reddel RR; Samra JS; Kench JG; Merrett ND; Epari K; Nguyen NQ; Zeps N; Falconi M; Simbolo M; Butturini G; Van Buren G; Partelli S; Fassan M; Khanna KK; Gill AJ; Wheeler DA; Gibbs RA; Musgrove EA; Bassi C; Tortora G; Pederzoli P; Pearson JV; Waddell N; Biankin AV; Grimmond SM, 2017, 'Whole-genome landscape of pancreatic neuroendocrine tumours (vol 543, pg 65, 2017)', NATURE, vol. 550, pp. 548 - 548, http://dx.doi.org/10.1038/nature24026
    Journal articles | 2017
    Dr Mark Pinese
    Balachandran VP; Łuksza M; Zhao JN; Makarov V; Moral JA; Remark R; Herbst B; Askan G; Bhanot U; Senbabaoglu Y; Wells DK; Cary CIO; Grbovic-Huezo O; Attiyeh M; Medina B; Zhang J; Loo J; Saglimbeni J; Abu-Akeel M; Zappasodi R; Riaz N; Smoragiewicz M; Larkin Kelley Z; Basturk O; Gönen M; Levine AJ; Allen PJ; Fearon DT; Merad M; Gnjatic S; Iacobuzio-Donahue CA; Wolchok JD; Dematteo RP; Chan TA; Greenbaum BD; Merghoub T; Leach SD; Johns AL; Scott Mead R; Gill AJ; Chang DK; McKay SH; Chantrill LA; Chin VT; Chou A; Humphris JL; Pajic M; Steinmann A; Arshi M; Drury A; Froio D; Morgan A; Timpson P; Hermann D; Vennin C; Warren S; Pinese M; Wu J; Pinho AV; Tucker K; Andrews L; Samra JS; Arena J; Pavlakis N; High HA; Mittal A; Biankin AV; Bailey P; Martin S; Musgrove EA; Jones MD; Nourse C; Jamieson NB; Stoita A; Williams D; Spigelman A; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Xu C; Grimmond SM; Hofmann O; Wilson PJ; Christ A; Bruxner T; Asghari R; Merrett ND; Pavey D; Das A; Goodwin A; Cosman PH; Ismail K, 2017, 'Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer', Nature, vol. 551, pp. S12 - S16, http://dx.doi.org/10.1038/nature24462
    Journal articles | 2017
    Dr Mark Pinese
    Hardie R-A; van Dam E; Cowley M; Han T-L; Balaban S; Pajic M; Pinese M; Iconomou M; Shearer RF; McKenna J; Miller D; Waddell N; Pearson JV; Grimmond SM; Sazanov L; Biankin AV; Villas-Boas S; Hoy AJ; Turner N; Saunders DN, 2017, 'Mitochondrial mutations and metabolic adaptation in pancreatic cancer', CANCER & METABOLISM, vol. 5, http://dx.doi.org/10.1186/s40170-017-0164-1
    Journal articles | 2017
    Dr Mark Pinese
    Harris NLE; Vennin C; Conway JRW; Vine KL; Pinese M; Cowley MJ; Shearer RF; Lucas MC; Herrmann D; Allam AH; Pajic M; Morton JP; Biankin AV; Ranson M; Timpson P; Saunders DN, 2017, 'SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer', Oncogene, vol. 36, pp. 4288 - 4298, http://dx.doi.org/10.1038/onc.2017.63
    Journal articles | 2017
    Dr Mark Pinese
    Vennin C; Chin VT; Warren SC; Lucas MC; Herrmann D; Magenau A; Melenec P; Walters SN; Del Monte-Nieto G; Conway JRW; Nobis M; Allam AH; McCloy RA; Currey N; Pinese M; Boulghourjian A; Zaratzian A; Adam AAS; Heu C; Nagrial AM; Chou A; Steinmann A; Drury A; Froio D; Giry-Laterriere M; Harris NLE; Phan T; Jain R; Weninger W; McGhee EJ; Whan R; Johns AL; Samra JS; Chantrill L; Gill AJ; Kohonen-Corish M; Harvey RP; Biankin AV; Evans TRJ; Anderson KI; Grey ST; Ormandy CJ; Gallego-Ortega D; Wang Y; Samuel MS; Sansom OJ; Burgess A; Cox TR; Morton JP; Pajic M; Timpson P, 2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, vol. 9, http://dx.doi.org/10.1126/scitranslmed.aai8504
    Journal articles | 2016
    Dr Mark Pinese
    Bailey P; Chang DK; Nones K; Johns AL; Patch AM; Gingras MC; Miller DK; Christ AN; Bruxner TJC; Quinn MC; Nourse C; Murtaugh LC; Harliwong I; Idrisoglu S; Manning S; Nourbakhsh E; Wani S; Fink L; Holmes O; Chin V; Anderson MJ; Kazakoff S; Leonard C; Newell F; Waddell N; Wood S; Xu Q; Wilson PJ; Cloonan N; Kassahn KS; Taylor D; Quek K; Robertson A; Pantano L; Mincarelli L; Sanchez LN; Evers L; Wu J; Pinese M; Cowley MJ; Jones MD; Colvin EK; Nagrial AM; Humphrey ES; Chantrill LA; Mawson A; Humphris J; Chou A; Pajic M; Scarlett CJ; Pinho AV; Giry-Laterriere M; Rooman I; Samra JS; Kench JG; Lovell JA; Merrett ND; Toon CW; Epari K; Nguyen NQ; Barbour A; Zeps N; Moran-Jones K; Jamieson NB; Graham JS; Duthie F; Oien K; Hair J; Grützmann R; Maitra A; Iacobuzio-Donahue CA; Wolfgang CL; Morgan RA; Lawlor RT; Corbo V; Bassi C; Rusev B; Capelli P; Salvia R; Tortora G; Mukhopadhyay D; Petersen GM; Munzy DM; Fisher WE; Karim SA; Eshleman JR; Hruban RH; Pilarsky C; Morton JP; Sansom OJ; Scarpa A; Musgrove EA; Bailey UMH; Hofmann O; Sutherland RL; Wheeler DA; Gill AJ; Gibbs RA; Pearson JV; Waddell N, 2016, 'Genomic analyses identify molecular subtypes of pancreatic cancer', Nature, vol. 531, pp. 47 - 52, http://dx.doi.org/10.1038/nature16965
    Journal articles | 2016
    Dr Mark Pinese
    Gingras MC; Covington KR; Chang DK; Donehower LA; Gill AJ; Ittmann MM; Creighton CJ; Johns AL; Shinbrot E; Dewal N; Fisher WE; Pilarsky C; Grützmann R; Overman MJ; Jamieson NB; Van Buren G; Drummond J; Walker K; Hampton OA; Xi L; Muzny DM; Doddapaneni H; Lee SL; Bellair M; Hu J; Han Y; Dinh HH; Dahdouli M; Samra JS; Bailey P; Waddell N; Pearson JV; Harliwong I; Wang H; Aust D; Oien KA; Hruban RH; Hodges SE; McElhany A; Saengboonmee C; Duthie FR; Grimmond SM; Biankin AV; Wheeler DA; Gibbs RA; Jones MD; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Smith Martyn M; Thomas MT; Chantrill LA; Chin VT; Angela C; Cowley MJ; Humphris JL; Mead S; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink LJ; Christ A; Bruxner T; Cloonan N; Newell F; Quinn M, 2016, 'Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation', Cell Reports, vol. 14, pp. 907 - 919, http://dx.doi.org/10.1016/j.celrep.2015.12.005
    Journal articles | 2016
    Dr Mark Pinese
    Kumar KR; Wali GM; Kamate M; Wali G; Minoche AE; Puttick C; Pinese M; Gayevskiy V; Dinger ME; Roscioli T; Sue CM; Cowley MJ, 2016, 'Defining the genetic basis of early onset hereditary spastic paraplegia using whole genome sequencing', Neurogenetics, vol. 17, pp. 265 - 270, http://dx.doi.org/10.1007/s10048-016-0495-z
    Journal articles | 2015
    Dr Mark Pinese
    Waddell N; Pajic M; Patch AM; Chang DK; Kassahn KS; Bailey P; Johns AL; Miller D; Nones K; Quek K; Quinn MCJ; Robertson AJ; Fadlullah MZH; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; Manning S; Nourse C; Nourbakhsh E; Wani S; Wilson PJ; Markham E; Cloonan N; Anderson MJ; Fink JL; Holmes O; Kazakoff SH; Leonard C; Newell F; Poudel B; Song S; Taylor D; Waddell N; Wood S; Xu Q; Wu J; Pinese M; Cowley MJ; Lee HC; Jones MD; Nagrial AM; Humphris J; Chantrill LA; Chin V; Steinmann AM; Mawson A; Humphrey ES; Colvin EK; Chou A; Scarlett CJ; Pinho AV; Giry-Laterriere M; Rooman I; Samra JS; Kench JG; Pettitt JA; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; Jamieson NB; Graham JS; Niclou SP; Bjerkvig R; Grützmann R; Aust D; Hruban RH; Maitra A; Iacobuzio-Donahue CA; Wolfgang CL; Morgan RA; Lawlor RT; Corbo V; Bassi C; Falconi M; Zamboni G; Tortora G; Tempero MA; Gill AJ; Eshleman JR; Pilarsky C; Scarpa A; Musgrove EA; Pearson JV; Biankin AV; Grimmond SM, 2015, 'Whole genomes redefine the mutational landscape of pancreatic cancer', Nature, vol. 518, pp. 495 - 501, http://dx.doi.org/10.1038/nature14169
    Journal articles | 2015
    Dr Mark Pinese
    Tactacan CM; Phua YW; Liu L; Zhang L; Humphrey ES; Cowley M; Pinese M; Biankin AV; Daly RJ, 2015, 'The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling', Molecular Cancer, vol. 14, http://dx.doi.org/10.1186/s12943-015-0412-3
    Journal articles | 2015
    Dr Mark Pinese
    Miller BW; Morton JP; Pinese M; Saturno G; Jamieson NB; Mcghee E; Timpson P; Leach J; Mcgarry L; Shanks E; Bailey P; Chang D; Oien K; Karim S; Au A; Steele C; Carter CR; Mckay C; Anderson K; Evans TRJ; Marais R; Springer C; Biankin A; Erler JT; Sansom OJ, 2015, 'Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: Inhibition of LOX abrogates metastasis and enhances drug efficacy', EMBO Molecular Medicine, vol. 7, pp. 1063 - 1076, http://dx.doi.org/10.15252/emmm.201404827
    Journal articles | 2015
    Dr Mark Pinese
    Susanto JM; Colvin EK; Pinese M; Chang DK; Pajic M; Mawson A; Caldon CE; Musgrove EA; Henshall SM; Sutherland RL; Biankin AV; Scarlett CJ, 2015, 'The epigenetic agents suberoylanilide hydroxamic acid and 5-AZA-2′ deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo', International Journal of Oncology, vol. 46, pp. 2223 - 2230, http://dx.doi.org/10.3892/ijo.2015.2894
    Journal articles | 2014
    Dr Mark Pinese
    Nagrial AM; Chang DK; Nguyen NQ; Johns AL; Chantrill LA; Humphris JL; Chin VT; Samra JS; Gill AJ; Pajic M; Pinese M; Colvin EK; Scarlett CJ; Chou A; Kench JG; Sutherland RL; Horvath LG; Biankin AV, 2014, 'Adjuvant chemotherapy in elderly patients with pancreatic cancer', British Journal of Cancer, vol. 110, pp. 313 - 319, http://dx.doi.org/10.1038/bjc.2013.722
    Journal articles | 2014
    Dr Mark Pinese
    Ali NA; Wu J; Hochgräfe F; Chan H; Nair R; Ye S; Zhang L; Lyons RJ; Pinese M; Lee HC; Armstrong N; Ormandy CJ; Clark SJ; Swarbrick A; Daly RJ, 2014, 'Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways', Breast Cancer Research, vol. 16, http://dx.doi.org/10.1186/s13058-014-0437-3
    Journal articles | 2014
    Dr Mark Pinese
    Humphris JL; Johns AL; Simpson SH; Cowley MJ; Pajic M; Chang DK; Nagrial AM; Chin VT; Chantrill LA; Pinese M; Mead RS; Gill AJ; Samra JS; Kench JG; Musgrove EA; Tucker KM; Spigelman AD; Waddell N; Grimmond SM; Biankin AV, 2014, 'Clinical and pathologic features of familial pancreatic cancer', Cancer, vol. 120, pp. 3669 - 3675, http://dx.doi.org/10.1002/cncr.28863
    Journal articles | 2014
    Dr Mark Pinese
    Nones K; Waddell N; Song S; Patch AM; Miller D; Johns A; Wu J; Kassahn KS; Wood D; Bailey P; Fink L; Manning S; Christ AN; Nourse C; Kazakoff S; Taylor D; Leonard C; Chang DK; Jones MD; Thomas M; Watson C; Pinese M; Cowley M; Rooman I; Pajic M; Butturini G; Malpaga A; Corbo V; Crippa S; Falconi M; Zamboni G; Castelli P; Lawlor RT; Gill AJ; Scarpa A; Pearson JV; Biankin AV; Grimmond SM, 2014, 'Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling', International Journal of Cancer, vol. 135, pp. 1110 - 1118, http://dx.doi.org/10.1002/ijc.28765
    Journal articles | 2013
    Dr Mark Pinese
    Kassahn KS; Holmes O; Nones K; Patch AM; Miller DK; Christ AN; Harliwong I; Bruxner TJ; Xu Q; Anderson M; Wood S; Leonard C; Taylor D; Newell F; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Steptoe A; Pajic M; Cowley MJ; Pinese M; Chang DK; Gill AJ; Johns AL; Wu J; Wilson PJ; Fink L; Biankin AV; Waddell N; Grimmond SM; Pearson JV, 2013, 'Somatic point mutation calling in low cellularity tumors', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0074380
    Journal articles | 2013
    Dr Mark Pinese
    Chou A; Waddell N; Cowley MJ; Gill AJ; Chang DK; Patch AM; Nones K; Wu J; Pinese M; Johns AL; Miller DK; Kassahn KS; Nagrial AM; Wasan H; Goldstein D; Toon CW; Chin V; Chantrill L; Humphris J; Mead RS; Rooman I; Samra JS; Pajic M; Musgrove EA; Pearson JV; Morey AL; Grimmond SM; Biankin AV, 2013, 'Clinical and molecular characterization of HER2 amplified-pancreatic cancer', Genome Medicine, vol. 5, http://dx.doi.org/10.1186/gm482
    Journal articles | 2013
    Dr Mark Pinese
    Chang DK; Jamieson N; Johns A; Scarlett CJ; Pajic M; Biankin AV; et A, 2013, 'Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater', Journal of Clinical Oncology, vol. 31, pp. 1348 - 1356, http://dx.doi.org/10.1200/JCO.2012.46.8868
    Journal articles | 2013
    Dr Mark Pinese
    Chantrill L; Johns A; Nagrial A; Chin V; Chou A; Pinese M; Mead S; Gebski V; Sjoguist K; Lee C; Yip S; Miller D; Sebastian L; Asghari R; Harvey S; Paviakis N; Mukhedkar S; Grimison P; Miller D; Pearson J; Waddell N; Grimmond S; Simes J; Biankin A, 2013, 'The IMPaCT trial: Individualised Molecular Pancreatic Cancer Therapy. A pilot, randomized, open label Phase II trial assessing first line treatment with gemcitabine or personalized treatment based on tumour molecular signature in patients with metastatic pancreatic cancer.', MOLECULAR CANCER THERAPEUTICS, vol. 12, http://dx.doi.org/10.1158/1535-7163.TARG-13-A75
    Journal articles | 2013
    Dr Mark Pinese
    Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', Journal of Clinical Oncology, vol. 31, pp. e15029 - e15029, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15029
    Journal articles | 2012
    Dr Mark Pinese
    Perez-Mancera P; Rust AG; van der Weyden L; Kristiansen GO; Kristiansen GO; Li A; Sarver AL; Silverstein KAT; Grutzmann R; Aust DE; Rummele P; Knosel T; Herd C; Stemple D; Kettleborough R; Brosnan JA; Li A; Richard GM; Knight S; Yu J; Stegeman S; Collier LS; Ten Hoeve JJ; De Ridder J; Klein A; Goggins M; Hruban R; Chang D; Biankin AV; Pinese M; Grimmond S; Wessels L; Wood S; Iacobuzio-donahue CA; Pilarsky CP; Largaespada DA; Adams DJ; Tuveson DA, 2012, 'The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma', Nature, vol. 486, pp. 266 - 270, http://dx.doi.org/10.1038/nature11114
    Journal articles | 2011
    Dr Mark Pinese
    Colvin EK; Susanto J; Kench JG; Ong V; Mawson AJ; Pinese M; Chang DK; Rooman I; O'Toole S; Segara D; Musgrove EA; Sutherland RL; Apte MV; Scarlett C; Biankin AV, 2011, 'Retinoid signaling in pancreatic cancer, injury and regeneration', PLoS One, vol. 6, pp. e29075, http://dx.doi.org/10.1371/journal.pone.0029075
    Journal articles | 2011
    Dr Mark Pinese
    Chang DK; Colvin EK; Scarlett CJ; Pajic M; Pinese M; Gill AJ; Musgrove EA; Sutherland R; Kench J; Biankin AV, 2011, 'A molecular prognostic nomogram for resectable pancreatic cancer', JOURNAL OF CLINICAL ONCOLOGY, vol. 29, http://dx.doi.org/10.1200/jco.2011.29.4_suppl.154
    Journal articles | 2010
    Dr Mark Pinese
    Zardawi SJ; Zardawi I; Mcneil CM; Millar E; Mcleod D; Morey AL; Crea P; Murphy NC; Pinese M; Lopez-Knowles E; Oakes SR; Ormandy CJ; Qiu MR; Hamilton A; Spillane AJ; Lee CS; Sutherland RL; Musgrove EA; O'Toole S, 2010, 'High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype', Histopathology, vol. 56, pp. 286 - 296, http://dx.doi.org/10.1111/j.1365-2559.2009.03475.x
    Journal articles | 2009
    Dr Mark Pinese
    Chong J; Prall O; Chandrakanthan V; Xaymardan M; Ahmed I; Scarlett C; Colvin E; Pinese M; Biankin A; Harvey R, 2009, 'Sca1+/CD31−/PDGFRa+ Cardiac Stem Cells are from an Epicardial/Mesodermal but not Neural-crest, Cardiomyocyte or Bone-marrow Origin', Heart, Lung and Circulation, vol. 18, pp. S3 - S3, http://dx.doi.org/10.1016/j.hlc.2009.05.005
    Journal articles | 2009
    Dr Mark Pinese
    Chang DK; Colvin EK; Scarlett CJ; Pinese M; Goldstein D; Merrett ND; Musgrove EA; Henshall SM; Sutherland RL; Kench JG; Biankin AV, 2009, 'Biomarkers of Gemcitabine Response in Pancreatic Cancer', PANCREAS, vol. 38, pp. 987 - 988, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300058&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2009
    Dr Mark Pinese
    Johns AL; Colvin EK; Pinese M; Gill AJ; Hruban RH; Eshleman JR; Maitra A; Grimmond SM; Biankin AV, 2009, 'Development of a Biological Resource for Genomic Characterisation of Pancreatic Cancer', PANCREAS, vol. 38, pp. 1011 - 1011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2009
    Dr Mark Pinese
    Pinese M; Chang DK; Colvin EK; Kench JG; Johns AL; Henshall SM; Sutherland RL; Biankin AV, 2009, 'A Preoperative Prognostic Nomogram for Pancreatic Cancer', PANCREAS, vol. 38, pp. 1039 - 1039, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300295&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2009
    Dr Mark Pinese
    Colvin EK; Scarlett CJ; Pinese M; Biankin AV, 2009, 'Assessment of Retinoic Acid Signaling in the Normal Adult Pancreas, Pancreatic Injury and Regeneration and Pancreatic Cancer', PANCREAS, vol. 38, pp. 990 - 990, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300069&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2007
    Dr Mark Pinese
    Stefani M; Markus MA; Lin RC; Dawes IW; Morris B, 2007, 'The effect of resveratrol on a cell model of human aging.', Annals of the New York Academy of Sciences, vol. 1114, pp. 407 - 418, http://dx.doi.org/10.1196/annals.1396.001
    Journal articles | 2006
    Dr Mark Pinese
    Morris BJ; Stefani M; Markus MA; Pinese M; Lin RCY; Dawes IW, 2006, 'Resveratrol induces expression of genes beneficial to health of mortal human fibroblasts in culture.', Journal of Hypertension, vol. 24, pp. 396
  • Conference Abstracts | 2020
    Dr Mark Pinese
    Sullivan P; Mayoh C; Wong-Erasmus M; Gayevskiy V; Beecroft S; Pinese M; Oates E; Cowley M, 2020, 'Introme identifies non-canonical splice-altering variants in neuromuscular patients resulting in multiple new genetic diagnoses', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, ELECTR NETWORK, Vol. 30, pp. S144 - S144, presented at 25th International Congress of the World-Muscle-Society (WMS), ELECTR NETWORK, 28 September 2020 - 02 October 2020, http://dx.doi.org/10.1016/j.nmd.2020.08.330
    Conference Papers | 2020
    Dr Mark Pinese
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a03
    Conference Papers | 2019
    Dr Mark Pinese
    Ballinger ML; Pinese M; Thomas DM, 2019, 'Translating genomic risk into an early detection strategy for sarcoma', in Genes Chromosomes and Cancer, United States, pp. 130 - 136, United States, http://dx.doi.org/10.1002/gcc.22697
    Conference Abstracts | 2019
    Dr Mark Pinese
    Thavaneswaran S; Ballinger ML; Grady J; Cowley M; Joshua A; Sebastian L; Collignon E; Silvestri A; Kansara M; Pinese M; Sjoquist KM; Hague W; Lee CK; Simes J; Thomas DM, 2019, 'The Cancer Molecular Screening and Therapeutics Program (MoST): Actionable mutation frequencies in a population with rare and less common cancers.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.3136
    Conference Abstracts | 2019
    Dr Mark Pinese
    Pavanello M; Dicks E; Song H; Ariff A; Bolithon A; Intermaggio MP; Pinese M; Moysich K; Odunsi KO; Goode E; Bowtell DD; Fasching P; Doherty JA; Modugno F; Kjaer SK; Webb PM; Wu A; deFazio A; James P; Subramanian D; Campbell I; Gayther SA; Pharoah PDP; Ramus SJ, 2019, 'Germline mutations in new susceptibility genes for non-high-grade serous ovarian cancer.', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 26, pp. 98 - 99, presented at AACR Special Conference on Advances in Ovarian Cancer Research, Atlanta, GA, 13 September 2019 - 16 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000546013300152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Dr Mark Pinese
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Dong-Anh K-Q; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O'Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2019, 'Prevalence and spectrum of germline mutations in children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Montreal, CANADA, Vol. 80, pp. 42 - 43, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, Montreal, CANADA, 17 September 2019 - 20 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Dr Mark Pinese
    Fuentes-Bolanos N; Warby M; Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang DA; Amit K; Lau L; Mayoh C; Marshall G; Mould E; O'Brien TA; Pinese M; Thomas D; Tyrrell V; Ziegler D; Harber M; Tucker KM, 2019, 'Prevalence and Spectrum of Germline Mutations in Children with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S503 - S504, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458005160&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Mark Pinese
    Tyrrell V; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Mould E; O'Brien T; Pinese M; Khuong-Quang DA; Thomas D; Trahair T; Tsoli M; Tucker K; Wharby M; Wong M; Xie J; Ziegler D, 2018, 'Zero childhood cancer – Accelerating translation of experimental oncology: Better matching drug to target', in Pathology, Elsevier BV, Vol. 50, pp. S31 - S31, http://dx.doi.org/10.1016/j.pathol.2017.12.072
    Conference Abstracts | 2018
    Dr Mark Pinese
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin J; Gayevski V; Kumar A; Kaplan W; Ekert P; Franshaw L; Gifford A; Weber M; Rodriguez M; Mayoh C; Cohn R; Arndt G; Lock R; Tyrrell V; Norris M; Haber M; Lau L; Dong AKQ; Wong M; Trahair T; Marshall GM; Cowley MJ; Ziegler DS, 2018, 'Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-137
    Conference Abstracts | 2018
    Dr Mark Pinese
    Dreyer S; Jamieson N; Pinese M; Upstill-Goddard R; Mckay C; Duthie F; Biankin A; Chang D, 2018, 'Precision oncology in surgery: Patient selection biomarkers for operable pancreatic cancer', in BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Glasgow, SCOTLAND, Vol. 119, pp. 48 - 48, presented at National-Cancer-Research-Institute (NCRI) Cancer Conference, Glasgow, SCOTLAND, 04 November 2018 - 06 November 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000459278300135&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Mark Pinese
    Mould E; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Norris M; O'Brien T; Pinese M; Dong AKQ; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler D; Tyrrell V, 2018, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-138
    Conference Papers | 2018
    Dr Mark Pinese
    Pinese M; Ballinger M; Thomas D, 2018, 'Abstract IA03: Translating genomic risk into an early detection strategy for sarcoma', in Genomics, American Association for Cancer Research, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-ia03
    Conference Abstracts | 2018
    Dr Mark Pinese
    Barnet M; Jackson K; Gao B; Nagrial A; Boyer M; Cooper W; Hui R; Linton A; Tattersall M; Russell A; Gibson G; Cebon J; Long G; Menzies A; Scolyer R; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas D; Pinese M; Blinman P; Kao S; Goodnow C, 2018, 'Exploring the Germ-Line Contribution to Exceptional Response to PD-1/PD-L1 Inhibition in Patients with NSCLC by Whole Genome Sequencing', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Vol. 13, pp. S529 - S529, http://dx.doi.org/10.1016/j.jtho.2018.08.726
    Conference Papers | 2018
    Dr Mark Pinese
    Barnet MB; Jackson KJ; Gao B; Nagrial AM; Boyer MJ; Cooper WA; Hui R; Linton A; Tattersall MH; Gibson G; Cebon J; Long GV; Menzies AM; Scolyer RA; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas DM; Pinese M; Blinman P; Kao S; Goodnow CC, 2018, 'Exploring the germ-line contribution to exceptional response to PD-1/PD-L1 inhibition in patients with metastatic non-small-cell lung cancer by whole genome sequencing', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-121
    Conference Abstracts | 2018
    Dr Mark Pinese
    McCabe MJ; Pinese M; Sheriff N; Fazekas M; McCormack AI; Dinger ME; Cowley MJ, 2018, 'Whole genome - and targeted capture - sequencing analysis of dual lung metastases and circulating tumour DNA (ctDNA) in a rare Primary Adrenocortical Carcinoma (ACC) case', in HUMAN GENOMICS, BIOMED CENTRAL LTD, Vol. 12, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000427728400112&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Mark Pinese
    Chan I; Dicks E; Intermaggio M; Song H; Tyrer J; Zhu Q; Moysich K; Odunsi K; Pharoah P; Gayther S; Pinese M; Ramus S, 2018, 'Identification of 17 Candidate Ovarian Cancer Genes from Whole-exome Sequencing in 15 Ovarian Cancer Families', in AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, WILEY, Vol. 58, pp. 16 - 16, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000443678800043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Dr Mark Pinese
    Sheriff N; Pinese M; Fazekas M; McCabe M; Cowley M; McCormack AI, 2017, 'TrACCing the tumour', in CLINICAL ENDOCRINOLOGY, WILEY-BLACKWELL, Vol. 86, pp. 60 - 60, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000393453600153&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2017
    Dr Mark Pinese
    Pinese M; Lacaze P; Rath E; Chuah A; Degrave D; Husson S; Kaplin W; Andrews D; Barr M; Thomas D; Dinger M, 2017, 'The Medical Genome Reference Bank – Deep genomics of a disease-depleted, elderly Australian population', presented at ComBio2017, Adelaide, -
    Conference Papers | 2016
    Dr Mark Pinese
    McKay S; Humphris J; Johns A; Pinese M; Patch A-M; Nones K; Grimmond S; Biankin A; Waddell N, 2016, 'Abstract A02: Assessment of germline cancer predisposition genes in 392 unselected pancreatic cancer patients', in Epidemiology and Risk Factors, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Advances in Science and Clinical Care; May 12-15, 2016; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.panca16-a02
    Conference Abstracts | 2016
    Dr Mark Pinese
    McCabe M; Cowley M; De Sousa S; Pinese M; Gayevskiy V; Minoche A; McCormack A; Dinger M, 2016, 'Establishment of the Southern Hemisphere's First Clinically Accredited Whole Genome Sequencing Facility, and the Development of a Gene Sequencing Panel for Application to Disparate Cancer Types Including Pituitary', in HORMONE RESEARCH IN PAEDIATRICS, KARGER, Vol. 86, pp. 35 - 35, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000388504100071&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2016
    Dr Mark Pinese
    Jasper MJ; Hardy T; Pinese M; McCabe M; Ledger W; Fraser M, 2016, 'Next generation sequencing (NGS) metrics following DOP-PCR whole genome amplification (WGA) of single and multi-cell samples for PGS', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, pp. 402 - 402, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000453583903205&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Dr Mark Pinese
    Chin VT; Conway J; Nagrial A; Chantrill LA; Chou A; Steinmann A; Gill A; Pinese M; Wu J; Johns A; Dury A; Biankin A; Timpson P; Pajic M, 2015, 'Targeting the Rho-ROCK pathway to treat pancreatic cancer: The use of unique preclinical models to ascertain the effects on cancer growth and metastasis', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, San Francisco, CA, Vol. 33, presented at Gastrointestinal Cancers Symposium, San Francisco, CA, 15 January 2015 - 17 January 2015, http://dx.doi.org/10.1200/jco.2015.33.3_suppl.312
    Conference Papers | 2013
    Dr Mark Pinese
    Chang DK; Pinese M; Scarlett CJ; Pajic M; Colvin EK; Johns AL; Wu J; Cowley MJ; Humphris JL; Chou A; Nguyen NQ; Nagrial AM; Chantrill L; Chin VT; Musgrove EA; Altekruse S; Gill AJ; Kench JG; Biankin AV, 2013, 'A molecular pre-operative prognostic nomogram for resectable pancreatic cancer', in Cancer Research, American Association for Cancer Research, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-1156
    Conference Abstracts | 2013
    Dr Mark Pinese
    Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 31, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 31 May 2013 - 04 June 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419603693&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2013
    Dr Mark Pinese
    Chin V; Nagrial A; Chang D; Chantrill L; Cowley M; Wu J; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Gill A; Timpson P; Biankin A; Pajic M, 2013, 'From function genomics to precision medicine: the therapeutic potential of targeting rock signalling in pancreatic cancer', Chicago, IL, Vol. 9, pp. 53 - 53, presented at ASCO Annual Meeting, Chicago, IL, 31 May 2013 - 04 June 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000329462300024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Dr Mark Pinese
    Chang DK; Chou A; Nguyen NQ; Nagrial AM; Chantrill LA; Chin VT; Musgrove EA; Sutherland RL; Gill AJ; Altekruse S; Kench JG; Scarlett CJ; Biankin AV; Pinese M; Pajic M; Colvin EK; Johns AL; Humphris JL; Wu J; Cowley MJ, 2012, 'Abstract B64: A molecular preoperative prognostic nomogram for resectable pancreatic cancer.', in Tumor Biology, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Progress and Challenges; June 18-21, 2012; Lake Tahoe, NV, http://dx.doi.org/10.1158/1538-7445.panca2012-b64
    Conference Papers | 2009
    Dr Mark Pinese
    Chong JJ; Xaymardan M; Prall O; Chandrakanthan V; Ahmed I; Asli N; Bouveret R; Scarlett C; Colvin E; Pinese M; Biankin A; Harvey RP, 2009, 'Cardiac Stem Cells Defined by Colony Forming Unit Assays Are From an Epicardial/Mesodermal but Not Neural-Crest, Cardiomyocyte or Bone-Marrow Origin', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Orlando, FL, pp. S808 - S808, presented at 82nd Scientific Session of the American-Heart-Association, Orlando, FL, 14 November 2009 - 18 November 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271831502450&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Dr Mark Pinese
    Biankin AV; Kench JG; Colvin EK; Segara D; Scarlett CJ; Nguyen N; Chang D; Lee CS; Morey AL; Pinese M; Kuo S; Susanto J; Cosman PH; Linderman GJ; Visvader J; Merrett ND; Henshall SM; Musgrove EA; Sutherland RL, 2008, 'Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer', in Pancreas, Lippincott Williams & Wilkins, pp. 462 - 462, http://dx.doi.org/10.1053/j.gastro.2009.04.009
    Conference Papers | 2008
    Dr Mark Pinese
    Colvin EK; Susanto JM; O Toole S; Kench JG; Mawson AJ; Ong V; Pinese M; Scarlett CJ; Biankin AV, 2008, 'Loss of CRBP1 expression, a key component of retinoic acid signalling, is a common and early event in pancreatic cancer', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 397 - 397, presented at Pancreas, http://dx.doi.org/10.1097/01.mpa.0000297682.15697.42
    Conference Presentations | 2008
    Dr Mark Pinese
    Susanto JM; Colvin EK; Scarlett CJ; Ong V; Mawson AJ; Pinese M; Biankin AV, 2008, 'Retinoids, in combination with Histone Deacetylase (HDAC) inhibitors, as a potential therapy for pancreatic cancer', Vol. 6, pp. 29 - 29, presented at 20th Meeting of the European Association for Cancer Research, Lyon, FRANCE, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71287-4
    Conference Papers | 2008
    Dr Mark Pinese
    Colvin EK; Scarlett CJ; Pinese M; O Toole S; Ong V; Susanto JM; Mawson AJ; Chang D; Sutherland RL; Biankin AV, 2008, 'TRANSDIFFERENTIATION OF BONE MARROW DERIVED STEM CELLS INTO MATURE PANCREATIC ACINAR CELLS', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 465 - 465, presented at Pancreas, http://dx.doi.org/10.1097/01.MPA.0000335433.02228.5b
    Conference Papers | 2008
    Dr Mark Pinese
    Biankin AV; Kench JG; Colvin EK; Segara D; Scarlett CJ; Nguyen N; Chang D; Morey AL; Lee CS; Pinese M; Kuo S; Susanto JM; Cosman PH; Lindeman GJ; Visvader J; Merrett ND; Musgrove EA; Henshall SM; Sutherland RL, 2008, 'EXPRESSION OF S100A2 CALCIUM-BINDING PROTEIN PREDICTS RESPONSE TO PANCREATECTOMY FOR PANCREATIC CANCER', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 462 - 462, presented at Pancreas, http://dx.doi.org/10.1097/01.MPA.0000335385.14896.99

Awards

  • Best Presentation by an Early Career Researcher, AGTA Annual Conference, 2017
  • Precision FDA Truth Challenge, Highest SNP Precision Winner, US FDA, 2016
  • University Medal in Molecular Biology, UNSW Sydney, 2005

Grants

Cancer Australia Priority-Driven Collaborative Cancer Research Scheme -- Comprehensively surveying the complex genetic determinants of sarcoma risk, 2018
National Computational Infrastructure Merit Allocation Scheme -- A whole genome study to map heritable risk in sarcoma, 2017

 

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