Professor Martin Holke Olof Ugander
Honorary Professor

Professor Martin Holke Olof Ugander

Honorary Professor, UNSW (2020)

Fellow of the Cardiac Society of Australia and New Zeeland (2019)

Professor of Cardiac Imaging, University of Sydney (2019)

Associate Professor, Karolinska Institutet, Sweden (2016)

Post-doctoral research fellow, National Institutes of Health (NIH), USA (2009-2011)

PhD, Lund University, Sweden (2006)

MD, Lund University, Sweden (2001

Medicine & Health
School of Clinical Medicine

Professor Martin Ugander, MD, PhD, FCSANZ, is an Honorary Professor at St Vincent’s Clinical School, Faculty of Medicine, UNSW, since 2020. He is Professor of Cardiac Imaging at the University of Sydney since 2019. He was born 1975 in Sweden, and grew up in the USA. He received his MD in 2001 and PhD in 2006 from Lund University, Sweden. 2009-2011 he was a Post-doctoral Research Fellow in Cardiovascular MRI and CT at the National Institutes of Health (NIH), USA. 2011-2019 he undertook clinical training in the medical specialty Clinical Physiology at Karolinska University Hospital, Stockholm, Sweden, where he also founded and led the Karolinska Cardiovascular Magnetic Resonance clinical and translational research group at the Karolinska Institute. He continues to hold an affiliation with the Karolinska Institute.

  • Journal articles | 2022
    Lundin M; Sörensson P; Maret E; Jenner J; Abdula G; Nickander J; Themudo R; Caidahl K; Kellman P; Sigfridsson A; Ugander M, 2022, 'Diffusely Increased Myocardial Extracellular Volume With or Without Focal Late Gadolinium Enhancement: Prevalence and Associations With Left Ventricular Size and Function.', J Thorac Imaging, vol. 37, pp. 17 - 25, http://dx.doi.org/10.1097/RTI.0000000000000515
    Journal articles | 2020
    Atwater BD; Emerek K; Samad Z; Sze E; Black-Maier E; Loring Z; Ugander M; Liao L; Kisslo J; Søgaard P; Friedman DJ, 2020, 'Predicting the Development of Reduced Left Ventricular Ejection Fraction in Patients With Left Bundle Branch Block.', Am J Cardiol, vol. 137, pp. 39 - 44, http://dx.doi.org/10.1016/j.amjcard.2020.09.034
    Journal articles | 2020
    Dennis M; Ugander M; Kozor R; Puranik R, 2020, 'Cardiovascular Magnetic Resonance Imaging of Inherited Heart Conditions.', Heart Lung Circ, vol. 29, pp. 584 - 593, http://dx.doi.org/10.1016/j.hlc.2019.12.008
    Journal articles | 2020
    Ekström M; Hellman A; Hasselström J; Hage C; Kahan T; Ugander M; Wallén H; Persson H; Linde C, 2020, 'The transition from hypertension to hypertensive heart disease and heart failure: the PREFERS Hypertension study.', ESC Heart Fail, vol. 7, pp. 737 - 746, http://dx.doi.org/10.1002/ehf2.12612
    Journal articles | 2020
    Fröjdh F; Fridman Y; Bering P; Sayeed A; Maanja M; Niklasson L; Olausson E; Pi H; Azeem A; Wong TC; Kellman P; Feingold B; Christopher A; Fukui M; Cavalcante JL; Miller CA; Butler J; Ugander M; Schelbert EB, 2020, 'Extracellular Volume and Global Longitudinal Strain Both Associate With Outcomes But Correlate Minimally.', JACC Cardiovasc Imaging, vol. 13, pp. 2343 - 2354, http://dx.doi.org/10.1016/j.jcmg.2020.04.026
    Journal articles | 2020
    Goldberg YH; Megyessi D; Flam M; Spevack DM; Sundqvist MG; Ugander M, 2020, 'Mechanistic validation of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging Guidelines for the assessment of diastolic dysfunction in heart failure with reduced ejection fraction.', Cardiovasc Ultrasound, vol. 18, pp. 42, http://dx.doi.org/10.1186/s12947-020-00224-z
    Journal articles | 2020
    Grankvist R; Chireh A; Sandell M; Mukarram AK; Jaff N; Berggren I; Persson H; Linde C; Arnberg F; Lundberg J; Ugander M; La Manno G; Jonsson S; Daub CO; Holmin S, 2020, 'Myocardial micro-biopsy procedure for molecular characterization with increased precision and reduced trauma.', Sci Rep, vol. 10, pp. 8029, http://dx.doi.org/10.1038/s41598-020-64900-w
    Journal articles | 2020
    Loring Z; Friedman DJ; Emerek K; Graff C; Sørensen PL; Hansen SM; Wieslander B; Ugander M; Søgaard P; Atwater BD, 2020, 'Lead one ratio in left bundle branch block predicts poor cardiac resynchronization therapy response.', Pacing Clin Electrophysiol, vol. 43, pp. 503 - 510, http://dx.doi.org/10.1111/pace.13916
    Journal articles | 2020
    Nickander J; Lundin M; Abdula G; Jenner J; Maret E; Sörensson P; Heiberg E; Sigfridsson A; Ugander M, 2020, 'Stationary tissue background correction increases the precision of clinical evaluation of intra-cardiac shunts by cardiovascular magnetic resonance.', Sci Rep, vol. 10, pp. 5053, http://dx.doi.org/10.1038/s41598-020-61812-7
    Journal articles | 2020
    Nickander J; Themudo R; Sigfridsson A; Xue H; Kellman P; Ugander M, 2020, 'Females have higher myocardial perfusion, blood volume and extracellular volume compared to males – an adenosine stress cardiovascular magnetic resonance study', Scientific Reports, vol. 10, pp. 10380, http://dx.doi.org/10.1038/s41598-020-67196-y
    Journal articles | 2020
    Ramos JG; Fyrdahl A; Wieslander B; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M, 2020, 'Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure', BMC Medical Genetics, vol. 21, pp. 28, http://dx.doi.org/10.1186/s12880-020-00428-9
    Journal articles | 2020
    Ramos JG; Fyrdahl A; Wieslander B; Thalén S; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M, 2020, 'Comprehensive Cardiovascular Magnetic Resonance Diastolic Dysfunction Grading Shows Very Good Agreement Compared With Echocardiography', JACC: Cardiovascular Imaging, vol. 13, pp. 2530 - 2542, http://dx.doi.org/10.1016/j.jcmg.2020.06.027
    Journal articles | 2020
    Rysz S; Lundberg J; Nordberg P; Eriksson H; Wieslander B; Lundin M; Fyrdahl A; Pernow J; Ugander M; Djärv T; Jonsson Fagerlund M, 2020, 'The effect of levosimendan on survival and cardiac performance in an ischemic cardiac arrest model - A blinded randomized placebo-controlled study in swine.', Resuscitation, vol. 150, pp. 113 - 120, http://dx.doi.org/10.1016/j.resuscitation.2020.02.032
    Journal articles | 2020
    Sundqvist MG; Sahlén A; Ding ZP; Ugander M, 2020, 'Diastolic function and its association with diabetes, hypertension and age in an outpatient population with normal stress echocardiography findings.', Cardiovasc Ultrasound, vol. 18, pp. 46, http://dx.doi.org/10.1186/s12947-020-00228-9
    Journal articles | 2020
    Zong Y; Maanja M; Chaireti R; Schlegel TT; Ugander M; Antovic JP, 2020, 'Substantial prevalence of subclinical cardiovascular diseases in patients with hemophilia A evaluated by advanced electrocardiography.', J Electrocardiol, vol. 58, pp. 171 - 175, http://dx.doi.org/10.1016/j.jelectrocard.2019.12.008

Professor Ugander has a research interest in non-invasive cardiac imaging in general and cardiac magnetic resonance imaging (MRI) in particular, with a focus on the diagnoses ischemic heart disease, myocarditis, and heart failure, as well as basic cardiac pumping physiology. His research spans technical, pre-clinical translational, and clinical cardiovascular imaging using cardiac MRI, echocardiography, myocardial perfusion single-photon emission computed tomography (SPECT), x-ray computed tomography (CT), and electrocardiography (ECG).

 

Our current research specifically focuses on the challenges related to:

 

  • inefficient filling of the heart – diastolic dysfunction,
  • thick walls of the heart – left ventricular hypertrophy,
  • a reduction in blood flow to the smallest vessels of the heart – coronary microvascular dysfunction,
  • how these disease manifestations relate to chest pain and heart failure, in particular heart failure with preserved ejection fraction (HFpEF).