Dr Lenardon obtained a BSc (Hons) in Microbiology from UNSW in 2000, before going on to complete a PhD in Molecular Genetics in 2005 under the supervision of Prof. Ian Dawes. Megan then moved to the world-renowned Aberdeen Fungal Group (AFG) at the University of Aberdeen in Scotland where she worked as a postdoctoral research fellow with Profs. Neil Gow and Al Brown. During her postdoctoral years, her research focussed on fungal call wall structure and biosynthesis, with a particular interest in the regulation of chitin synthesis during the growth of Candida albicans, as well as the immune recognition of fungal cell wall components, and C. albicans stress responses. She set up her own group in the AFG in 2012 upon the receipt of a New Investigator award from the Medical Research Council (UK), and in 2017, returned to UNSW as a Senior Lecturer in the School of Biotechnology and Biomolecular Sciences.
Dr Lenardon has four research areas in her group - Candida albicans colonisation of the colon, cell wall structure and biosynthesis, cell division and septation in fungi, and antibody-based therapies and diagnostics for fungal infections (see Research Activities). She is the convenor of the Eukaryotic Microbes Special Interest Group of the Australian Society for Microbiology, an editorial board member of The Cell Surface, an Academic Editor for PLoS ONE, and a grant reviewer for the National Health and Medical Research Council (AU), Australian Research Council, Wellcome Trust (UK) and Biotechnology and Biological Sciences Research Council (UK).