Professor Megan Lord

Professor Megan Lord

Professor

Bachelor of Engineering (Chemical Engineering) (Hons I), University of New South Wales
Master of Biomedical Engineering, University of New South Wales
Doctor of Philosophy, University of New South Wales

Engineering
Grad Sch: Biomedical Eng

Megan Lord is a Professor and Australian Research Council (ARC) Future Fellow in the Graduate School of Biomedical Engineering and Academic Director of the Australian Graduate School of Engineering Industry PhD Program, Faculty of Engineering, UNSW Sydney.

Megan attained a Doctor of Philosophy in Engineering, Master of Biomedical Engineering, and a First class Honours degree in Chemical Engineering from UNSW Sydney.

Megan is recognised as a leader in the field of biomaterials (including nanomedicines and nanoparticles) and specifically the engineering of cell-biomaterial interactions for applications in drug delivery and tissue repair. Her research in underpinned by expertise in the analysis of cell-biomaterial interactions, matrix biology, and the biophysics of molecular interactions. She collaborates internationally across academia and industry.

Megan's research has been published in over 95 peer-reviewed publications and has been supported by multiple national grants including an ARC Australian Postdoctoral Fellowship (2010-2012) and an ARC Future Fellowship (2022-2026). Megan has mentored emerging academic and engineering leaders having supervised 22 PhD/MPhil and 140 Engineering Honours candidates to completion.

Megan's research leadership has been recognised by numerous awards including the Barry Preston Award from the Matrix Biology Society of Australia and New Zealand (2022) and a NSW Young Tall Poppy Award (2014). Her leadership is also evidenced by being elected to executive positions including President of the Matrix Biology Society of Australia and New Zealand (2019-2021; Past-President since 2022), Council Member for the International Society for Matrix Biology (since 2020) and Associate Editor of the IEEE Engineering in Medicine and Biology Society Conference Proceedings (since 2016). Megan also serves on the Standards Australia Committee HE-030 Biological and Clinical Evaluation of Medical Devices, which reviews and ratifies ISO 10993 and TC194, the international standard that evaluates the biocompatibility of medical devices and manages biological risk.

Megan is the founding Academic Director of the Australian Graduate School of Engineering Industry PhD Program within the Faculty of Engineering, UNSW Sydney where she has established a program with a focus on both academic and industry expertise supported by a mentoring and networking program to equip graduates with job-ready skills for their next career stage.

Megan is also the founding Academic Director of the Molecular Surface Interaction Laboratory within the Mark Wainwright Analytical Centre, UNSW Sydney. Her leadership has established a resource of world-class infrastructure for the measurement of dynamic interactions between molecules, cells, and materials with a user base across UNSW and other universities, and industry.

Phone
+61 2 9385 3910
Location
F25 Gordon and Jacqueline Samuels Building Level 5, Room 505 UNSW Sydney NSW 2052 AUSTRALIA
  • Book Chapters | 2015
    Vassie JA; Whitelock JM; Lord MS, 2015, 'Glycosaminoglycan functionalized nanoparticles exploit glycosaminoglycan functions', in , http://dx.doi.org/10.1007/978-1-4939-1714-3_44
  • Journal articles | 2024
    Adhikari A; Abayasingam A; Brasher NA; Kim HN; Lord M; Agapiou D; Maher L; Rodrigo C; Lloyd AR; Bull RA; Tedla N, 2024, 'Characterization of antibody-dependent cellular phagocytosis in patients infected with hepatitis C virus with different clinical outcomes', Journal of Medical Virology, 96, http://dx.doi.org/10.1002/jmv.29381
    Journal articles | 2024
    Jiang S; Wise SG; Kovacic JC; Rnjak-Kovacina J; Lord MS, 2024, 'Biomaterials containing extracellular matrix molecules as biomimetic next-generation vascular grafts', Trends in Biotechnology, 42, pp. 369 - 381, http://dx.doi.org/10.1016/j.tibtech.2023.09.009
    Journal articles | 2023
    Joukhdar H; Och Z; Tran H; Heu C; Vasquez GM; Sultana N; Stevens M; Dokos S; Lim KS; Lord MS; Rnjak-Kovacina J, 2023, 'Imparting Multi-Scalar Architectural Control into Silk Materials Using a Simple Multi-Functional Ice-Templating Fabrication Platform', Advanced Materials Technologies, 8, http://dx.doi.org/10.1002/admt.202201642
    Journal articles | 2023
    Kim HN; Elgundi Z; Lin X; Fu L; Tang F; Moh ESX; Jung MS; Chandrasekar K; Bartlett-Tomasetig F; Foster C; Packer NH; Whitelock JM; Rnjak-Kovacina J; Lord MS, 2023, 'Engineered short forms of perlecan enhance angiogenesis by potentiating growth factor signalling', Journal of Controlled Release, 362, pp. 184 - 196, http://dx.doi.org/10.1016/j.jconrel.2023.08.052
    Journal articles | 2023
    Lau K; Fu L; Zhang A; Akhavan B; Whitelock J; Bilek MM; Lord MS; Rnjak-Kovacina J, 2023, 'Recombinant perlecan domain V covalently immobilized on silk biomaterials via plasma immersion ion implantation supports the formation of functional endothelium', Journal of Biomedical Materials Research - Part A, 111, pp. 825 - 839, http://dx.doi.org/10.1002/jbm.a.37525
    Journal articles | 2023
    Sterling JD; Fu L; Pudun K; Baker S; Lord M, 2023, 'Salt doping of hyaluronic acid glycopolymer biocondensates', Biophysical journal, 122, http://dx.doi.org/10.1016/j.bpj.2022.11.1236
    Journal articles | 2022
    Adhikari A; Abayasingam A; Rodrigo C; Agapiou D; Pandzic E; Brasher NA; Fernando BSM; Keoshkerian E; Li H; Kim HN; Lord M; Popovic G; Rawlinson W; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Grubor-Bauk B; Lloyd AR; Martinello M; Bull RA; Tedla N; Lloyd AR; Kaldor J; Dore G; Sorrell T; Hudson B; Bartlett A; Lemberg D; Di Girolamo N; Byrne M; Hammoud M; Lloyd AR; Sultan R; Hudson B; Konecny P; Matthews G; Shek D; Holdaway S; Mitsa-Kos K; How-Chow D; Lagunday R; Robinson S; Terrill L; Joshi N; Li Y; Gill S; Sevehon A, 2022, 'Longitudinal Characterization of Phagocytic and Neutralization Functions of Anti-Spike Antibodies in Plasma of Patients after Severe Acute Respiratory Syndrome Coronavirus 2 Infection', Journal of Immunology, 209, pp. 1499 - 1512, http://dx.doi.org/10.4049/jimmunol.2200272
    Journal articles | 2022
    Fu L; Kim HN; Sterling JD; Baker SM; Lord MS, 2022, 'The role of the cell surface glycocalyx in drug delivery to and through the endothelium', Advanced Drug Delivery Reviews, 184, pp. 114195, http://dx.doi.org/10.1016/j.addr.2022.114195
    Journal articles | 2022
    Fu L; Li R; Whitelock JM; Lord MS, 2022, 'Tuning the intentional corona of cerium oxide nanoparticles to promote angiogenesis via fibroblast growth factor 2 signalling', Regenerative Biomaterials, 9, http://dx.doi.org/10.1093/rb/rbac081
    Journal articles | 2022
    Karimi F; Lau K; Kim HN; Och Z; Lim KS; Whitelock J; Lord M; Rnjak-Kovacina J, 2022, 'Surface Biofunctionalization of Silk Biomaterials Using Dityrosine Cross-Linking', ACS Applied Materials and Interfaces, 14, pp. 31551 - 31566, http://dx.doi.org/10.1021/acsami.2c03345
    Journal articles | 2022
    Lau K; Heu C; Moore MJ; Zhang A; Akhavan B; Wise SG; Bilek MMM; Lord MS; Rnjak-Kovacina J, 2022, 'Effect of plasma ion immersion implantation on physiochemical and biological properties of silk towards creating a versatile biomaterial platform', Materials Today Advances, 13, http://dx.doi.org/10.1016/j.mtadv.2022.100212
    Journal articles | 2022
    Liu J; Xue J; Fu L; Xu J; Lord MS; Liang K, 2022, 'Genetically Encoded Synthetic Beta Cells for Insulin Biosynthesis and Release under Hyperglycemic Conditions', Advanced Functional Materials, 32, http://dx.doi.org/10.1002/adfm.202111271
    Journal articles | 2022
    Yong JM; Fu L; Tang F; Yu P; Kuchel RP; Whitelock JM; Lord MS, 2022, 'ROS-Mediated Anti-Angiogenic Activity of Cerium Oxide Nanoparticles in Melanoma Cells', ACS Biomaterials Science and Engineering, 8, pp. 512 - 525, http://dx.doi.org/10.1021/acsbiomaterials.1c01268
    Journal articles | 2021
    Chandrasekar K; Farrugia BL; Johnson L; Marks D; Irving D; Elgundi Z; Lau K; Kim HN; Rnjak-Kovacina J; Bilek MM; Whitelock JM; Lord MS, 2021, 'Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100388
    Journal articles | 2021
    Joukhdar H; Seifert A; Jüngst T; Groll J; Lord MS; Rnjak-Kovacina J, 2021, 'Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications', Advanced Materials, 33, http://dx.doi.org/10.1002/adma.202100091
    Journal articles | 2021
    Lau K; Waterhouse A; Akhavan B; Gao L; Kim HN; Tang F; Whitelock JM; Bilek MM; Lord MS; Rnjak-Kovacina J, 2021, 'Biomimetic silk biomaterials: Perlecan-functionalized silk fibroin for use in blood-contacting devices', Acta Biomaterialia, 132, pp. 162 - 175, http://dx.doi.org/10.1016/j.actbio.2021.02.014
    Journal articles | 2021
    Lehmann RJ; Jolly LA; Johnson BV; Lord MS; Kim HN; Saville JT; Fuller M; Byers S; Derrick-Roberts ALK, 2021, 'Impaired neural differentiation of MPS IIIA patient induced pluripotent stem cell-derived neural progenitor cells', Molecular Genetics and Metabolism Reports, 29, http://dx.doi.org/10.1016/j.ymgmr.2021.100811
    Journal articles | 2021
    Liang J; Liu J; Lord MS; Wang Y; Liang K, 2021, 'De Novo Engineering of Metal–Organic Framework-Printed In Vitro Diagnostic Devices for Specific Capture and Release of Tumor Cells', Small, 17, http://dx.doi.org/10.1002/smll.202103590
    Journal articles | 2021
    Lord MS; Berret JF; Singh S; Vinu A; Karakoti AS, 2021, 'Redox Active Cerium Oxide Nanoparticles: Current Status and Burning Issues', Small, 17, http://dx.doi.org/10.1002/smll.202102342
    Journal articles | 2021
    Ng CY; Whitelock JM; Williams H; Kim HN; Medbury HJ; Lord MS, 2021, 'Macrophages bind LDL using heparan sulfate and the perlecan protein core', Journal of Biological Chemistry, 296, pp. 100520, http://dx.doi.org/10.1016/j.jbc.2021.100520
    Journal articles | 2020
    Bansal R; Elgundi Z; Care A; Goodchild SC; Lord MS; Rodger A; Sunna A, 2020, 'Elucidating the binding mechanism of a novel silica-binding peptide', Biomolecules, 10, pp. 4, http://dx.doi.org/10.3390/biom10010004
    Journal articles | 2020
    Bansal R; Elgundi Z; Goodchild SC; Care A; Lord MS; Rodger A; Sunna A, 2020, 'The effect of oligomerization on a solid-binding peptide binding to silica-based materials', Nanomaterials, 10, http://dx.doi.org/10.3390/nano10061070
    Journal articles | 2020
    Gao J; Wang WQ; Pei Q; Lord MS; Yu HJ, 2020, 'Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy', Acta Pharmacologica Sinica, 41, pp. 986 - 994, http://dx.doi.org/10.1038/s41401-020-0400-z
    Journal articles | 2020
    Lau K; Akhavan B; Lord MS; Bilek MM; Rnjak-Kovacina J, 2020, 'Dry Surface Treatments of Silk Biomaterials and Their Utility in Biomedical Applications', ACS Biomaterials Science and Engineering, 6, pp. 5431 - 5452, http://dx.doi.org/10.1021/acsbiomaterials.0c00888
    Journal articles | 2020
    Lin X; Tang F; Jiang S; Khamis H; Bongers A; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials', Adv. Sci., 7, pp. 2000900, http://dx.doi.org/10.1002/advs.202000900
    Journal articles | 2020
    Liu J; Guo Z; Kordanovski M; Kaltbeitzel J; Zhang H; Cao Z; Gu Z; Wich PR; Lord M; Liang K, 2020, 'Metal-organic frameworks as protective matrices for peptide therapeutics', Journal of Colloid and Interface Science, 576, pp. 356 - 363, http://dx.doi.org/10.1016/j.jcis.2020.05.057
    Journal articles | 2020
    Lord M; Whitelock J; Turnbull JE, 2020, 'Better growth-factor binding aids tissue repair', Nature Biomedical Engineering, 4, pp. 368 - 369, http://dx.doi.org/10.1038/s41551-020-0548-3
    Journal articles | 2020
    Lord MS; Melrose J; Day AJ; Whitelock JM, 2020, 'The Inter-α-Trypsin Inhibitor Family: Versatile Molecules in Biology and Pathology', Journal of Histochemistry and Cytochemistry, 68, pp. 907 - 927, http://dx.doi.org/10.1369/0022155420940067
    Journal articles | 2020
    Reijmers RM; Troeberg L; Lord MS; Petrey AC, 2020, 'Editorial: Proteoglycans and Glycosaminoglycan Modification in Immune Regulation and Inflammation', Frontiers in Immunology, 11, pp. 595867, http://dx.doi.org/10.3389/fimmu.2020.595867
    Journal articles | 2020
    Tang F; Manz XD; Bongers A; Odell RA; Joukhdar H; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'Microchannels are an architectural cue that promotes integration and vascularization of silk biomaterials in vivo', ACS Biomaterials Science and Engineering, 6, pp. 1476 - 1486, http://dx.doi.org/10.1021/acsbiomaterials.9b01624
    Journal articles | 2019
    Bansal R; Care A; Lord MS; Walsh TR; Sunna A, 2019, 'Experimental and theoretical tools to elucidate the binding mechanisms of solid-binding peptides', New Biotechnology, 52, pp. 9 - 18, http://dx.doi.org/10.1016/j.nbt.2019.04.001
    Journal articles | 2019
    Dinoro J; Maher M; Talebian S; Jafarkhani M; Mehrali M; Orive G; Foroughi J; Lord MS; Dolatshahi-Pirouz A, 2019, 'Sulfated polysaccharide-based scaffolds for orthopaedic tissue engineering', Biomaterials, 214, http://dx.doi.org/10.1016/j.biomaterials.2019.05.025
    Journal articles | 2019
    Farrugia BL; Mizumoto S; Lord MS; O’Grady RL; Kuchel RP; Yamada S; Whitelock JM, 2019, 'Hyaluronidase-4 is produced by mast cells and can cleave serglycin chondroitin sulfate chains into lower molecular weight forms', Journal of Biological Chemistry, 294, pp. 11458 - 11472, http://dx.doi.org/10.1074/jbc.RA119.008647
    Journal articles | 2019
    Gunawan C; Lord MS; Lovell E; Wong RJ; Jung MS; Oscar D; Mann R; Amal R, 2019, 'Oxygen-Vacancy Engineering of Cerium-Oxide Nanoparticles for Antioxidant Activity', ACS Omega, 4, pp. 9473 - 9479, http://dx.doi.org/10.1021/acsomega.9b00521
    Journal articles | 2019
    Lu M; Chen F; Cao C; Garvey CJ; Fletcher NL; Houston ZH; Lu H; Lord MS; Thurecht KJ; Stenzel MH, 2019, 'Importance of Polymer Length in Fructose-Based Polymeric Micelles for an Enhanced Biological Activity', Macromolecules, 52, pp. 477 - 486, http://dx.doi.org/10.1021/acs.macromol.8b02381
    Journal articles | 2019
    Palmer JC; Green RA; Boscher F; Poole-Warren LA; Carter PM; Enke YL; Lovell NH; Lord MS, 2019, 'Development and performance of a biomimetic artificial perilymph for in vitro testing of medical devices', Journal of Neural Engineering, 16, pp. 026006, http://dx.doi.org/10.1088/1741-2552/aaf482
    Journal articles | 2019
    Piloni A; Wong CK; Chen F; Lord M; Walther A; Stenzel MH, 2019, 'Surface roughness influences the protein corona formation of glycosylated nanoparticles and alter their cellular uptake', Nanoscale, 11, pp. 23259 - 23267, http://dx.doi.org/10.1039/c9nr06835j
    Journal articles | 2019
    Thickett SC; Hamilton E; Yogeswaran G; Zetterlund PB; Farrugia BL; Lord MS, 2019, 'Enhanced osteogenic differentiation of human fetal cartilage rudiment cells on graphene oxide-PLGA hybrid microparticles', Journal of Functional Biomaterials, 10, pp. 33, http://dx.doi.org/10.3390/jfb10030033
    Journal articles | 2018
    Farrugia B; Mi Y; Kim HN; Whitelock J; Baker S; Wiesmann W; Li Z; Maitz P; Lord M, 2018, 'Chitosan‐Based Heparan Sulfate Mimetics Promote Epidermal Formation in a Human Organotypic Skin Model', Advanced Functional Materials, 28, http://dx.doi.org/10.1002/adfm.201802818
    Journal articles | 2018
    Farrugia BL; Lord MS; Melrose J; Whitelock JM, 2018, 'The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies', Journal of Histochemistry and Cytochemistry, 66, pp. 321 - 336, http://dx.doi.org/10.1369/0022155417740881
    Journal articles | 2018
    Farrugia BL; Lord MS; Whitelock JM; Melrose J, 2018, 'Harnessing chondroitin sulphate in composite scaffolds to direct progenitor and stem cell function for tissue repair', Biomaterials Science, 6, pp. 947 - 957, http://dx.doi.org/10.1039/c7bm01158j
    Journal articles | 2018
    Kondyurin A; Lau K; Tang F; Akhavan B; Chrzanowski W; Lord MS; Rnjak-Kovacina J; Bilek MM, 2018, 'Plasma Ion Implantation of Silk Biomaterials Enabling Direct Covalent Immobilization of Bioactive Agents for Enhanced Cellular Responses', ACS Applied Materials and Interfaces, 10, pp. 17605 - 17616, http://dx.doi.org/10.1021/acsami.8b03182
    Journal articles | 2018
    Lord M; Rnjak-Kovacina J; Tang F; Whitelock J, 2018, 'Glycosaminoglycan and Proteoglycan-Based Biomaterials: Current Trends and Future Perspectives', Advanced Healthcare Materials, 7, pp. 1701042 - 1701042, http://dx.doi.org/10.1002/adhm.201701042
    Journal articles | 2018
    Lord MS; Tang F; Rnjak-Kovacina J; Smith JGW; Melrose J; Whitelock JM, 2018, 'The multifaceted roles of perlecan in fibrosis', Matrix Biology, 68-69, pp. 150 - 166, http://dx.doi.org/10.1016/j.matbio.2018.02.013
    Journal articles | 2018
    Palmer JC; Lord MS; Pinyon JL; Wise AK; Lovell NH; Carter PM; Enke YL; Housley GD; Green RA; Palmer J, 2018, 'Comparing perilymph proteomes across species', Laryngoscope, 128, pp. E47 - E52, http://dx.doi.org/10.1002/lary.26885
    Journal articles | 2018
    Tang F; Lord M; Stallcup W; Whitelock J, 2018, 'Cell surface chondroitin sulfate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulfate proteoglycan, perlecan, and is involved in cell adhesion', The Journal of Biochemistry
    Journal articles | 2018
    Vassie JA; Whitelock JM; Lord MS, 2018, 'Targeted Delivery and Redox Activity of Folic Acid-Functionalized Nanoceria in Tumor Cells', Molecular Pharmaceutics, 15, pp. 994 - 1004, http://dx.doi.org/10.1021/acs.molpharmaceut.7b00920
    Journal articles | 2017
    Guo M; Lord MS; Peng Z, 2017, 'Quantitative wear particle analysis for osteoarthritis assessment', Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 231, pp. 1116 - 1126, http://dx.doi.org/10.1177/0954411917735081
    Journal articles | 2017
    Kim HN; Whitelock JM; Lord MS, 2017, 'Structure-activity relationships of bioengineered heparin/heparan sulfates produced in different bioreactors', Molecules, 22, pp. 806, http://dx.doi.org/10.3390/molecules22050806
    Journal articles | 2017
    Lord MS; Cheng B; Farrugia BL; McCarthy S; Whitelock JM, 2017, 'Platelet factor 4 binds to vascular proteoglycans and controls both growth factor activities and platelet activation', Journal of Biological Chemistry, 292, pp. 4054 - 4063, http://dx.doi.org/10.1074/jbc.M116.760660
    Journal articles | 2017
    Lord MS; Ellis AL; Farrugia BL; Whitelock JM; Grenett H; Li C; O'Grady RL; DeCarlo AA, 2017, 'Perlecan and vascular endothelial growth factor-encoding DNA-loaded chitosan scaffolds promote angiogenesis and wound healing', Journal of Controlled Release, 250, pp. 48 - 61, http://dx.doi.org/10.1016/j.jconrel.2017.02.009
    Journal articles | 2017
    Lord MS; Jung MS; Whitelock JM, 2017, 'Optimization of bioengineered heparin/heparan sulfate production for therapeutic applications', Bioengineered, 8, pp. 661 - 664, http://dx.doi.org/10.1080/21655979.2017.1301328
    Journal articles | 2017
    Rnjak-Kovacina J; Tang F; Lin X; Whitelock JM; Lord MS, 2017, 'Recombinant Domain V of Human Perlecan Is a Bioactive Vascular Proteoglycan', Biotechnology Journal, 12, http://dx.doi.org/10.1002/biot.201700196
    Journal articles | 2017
    Vassie JA; Whitelock JM; Lord MS, 2017, 'Endocytosis of cerium oxide nanoparticles and modulation of reactive oxygen species in human ovarian and colon cancer cells', Acta Biomaterialia, 50, pp. 127 - 141, http://dx.doi.org/10.1016/j.actbio.2016.12.010
    Journal articles | 2016
    An H; Brettle M; Lee T; Heng B; Lim CK; Guillemin GJ; Lord MS; Klotzsch E; Geczy CL; Bryant K; Fath T; Tedla N, 2016, 'Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66', Journal of Cell Science, 129, pp. 1198 - 1209, http://dx.doi.org/10.1242/jcs.182006
    Journal articles | 2016
    Chang T; Gosain P; Stenzel MH; Lord MS, 2016, 'Drug-loading of poly(ethylene glycol methyl ether methacrylate) (PEGMEMA)-based micelles and mechanisms of uptake in colon carcinoma cells', Colloids and Surfaces B: Biointerfaces, 144, pp. 257 - 264, http://dx.doi.org/10.1016/j.colsurfb.2016.04.019
    Journal articles | 2016
    Chang T; Trench D; Putnam J; Stenzel MH; Lord MS, 2016, 'Curcumin-Loading-Dependent Stability of PEGMEMA-Based Micelles Affects Endocytosis and Exocytosis in Colon Carcinoma Cells', Molecular Pharmaceutics, 13, pp. 924 - 932, http://dx.doi.org/10.1021/acs.molpharmaceut.5b00820
    Journal articles | 2016
    Farrugia BL; Chandrasekar K; Johnson L; Whitelock JM; Marks D; Irving D; Lord M, 2016, 'Perspectives on the use of biomaterials to store platelets for transfusion', Biointerphases: an open access journal for the biomaterials interface community, 11, pp. 029701 - 029701, http://dx.doi.org/10.1116/1.4952450
    Journal articles | 2016
    Farrugia BL; Whitelock JM; O'Grady R; Caterson B; Lord MS, 2016, 'Mast Cells Produce a Unique Chondroitin Sulfate Epitope', Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 64, pp. 85 - 98, http://dx.doi.org/10.1369/0022155415620649
    Journal articles | 2016
    Hayes AJ; Shu CC; Lord MS; Little CB; Whitelock JM; Melrose J, 2016, 'Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc', European Cells and Materials, 32, pp. 40 - 57, http://dx.doi.org/10.22203/eCM.v032a03
    Journal articles | 2016
    Lord M; Chuang C; Rnjak‐Kovacina J; Cheng B; Lyons G; Whitelock J, 2016, 'Bioengineering Proteoglycan‐based Matrices For Blood Contacting Applications', The FASEB Journal, 30, http://dx.doi.org/10.1096/fasebj.30.1_supplement.622.2
    Journal articles | 2016
    Lord MS; Cheng B; Tang F; Lyons JG; Rnjak-Kovacina J; Whitelock JM, 2016, 'Bioengineered human heparin with anticoagulant activity', Metabolic Engineering, 38, pp. 105 - 114, http://dx.doi.org/10.1016/j.ymben.2016.07.006
    Journal articles | 2016
    Lord MS; Farrugia BL; Yan CMY; Vassie JA; Whitelock JM, 2016, 'Hyaluronan coated cerium oxide nanoparticles modulate CD44 and reactive oxygen species expression in human fibroblasts', Journal of Biomedical Materials Research - Part A, 104, pp. 1736 - 1746, http://dx.doi.org/10.1002/jbm.a.35704
    Journal articles | 2016
    Melrose J; Shu C; Whitelock JM; Lord MS, 2016, 'The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation', Matrix Biology, 52-54, pp. 363 - 383, http://dx.doi.org/10.1016/j.matbio.2016.01.008
    Journal articles | 2016
    Nandakumar D; Bendavid A; Martin PJ; Harris KD; Ruys AJ; Lord MS, 2016, 'Fabrication of Semiordered Nanopatterned Diamond-like Carbon and Titania Films for Blood Contacting Applications', ACS Applied Materials and Interfaces, 8, pp. 6802 - 6810, http://dx.doi.org/10.1021/acsami.5b11614
    Journal articles | 2016
    Rnjak-Kovacina J; Tang F; Whitelock JM; Lord MS, 2016, 'Silk biomaterials functionalized with recombinant domain V of human perlecan modulate endothelial cell and platelet interactions for vascular applications', Colloids and Surfaces B: Biointerfaces, 148, pp. 130 - 138, http://dx.doi.org/10.1016/j.colsurfb.2016.08.039
    Journal articles | 2016
    Shu CC; Jackson MT; Smith MM; Smith SM; Penm S; Lord MS; Whitelock JM; Little CB; Melrose J, 2016, 'Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis', Arthritis and Rheumatology, 68, pp. 868 - 879, http://dx.doi.org/10.1002/art.39529
    Journal articles | 2015
    Chen Y; Lord MS; Piloni A; Stenzel MH, 2015, 'Correlation between molecular weight and branch structure of glycopolymers stars and their binding to lectins', Macromolecules, 48, pp. 346 - 357, http://dx.doi.org/10.1021/ma501742v
    Journal articles | 2015
    Chrzanowski W; Lee JH; Kondyurin A; Lord MS; Jang J; Kim H; Bilek MMM, 2015, 'Biointerfaces: Nano‐Bio‐Chemical Braille for Cells: The Regulation of Stem Cell Responses using Bi‐Functional Surfaces (Adv. Funct. Mater. 2/2015)', Advanced Functional Materials, 25, pp. 339 - 339, http://dx.doi.org/10.1002/adfm.201570014
    Journal articles | 2015
    Chrzanowski W; Lee JH; Kondyurin A; Lord MS; Jang JH; Kim HW; Bilek MMM, 2015, 'Nano-Bio-Chemical Braille for Cells: The Regulation of Stem Cell Responses using Bi-Functional Surfaces', Advanced Functional Materials, 25, pp. 193 - 205, http://dx.doi.org/10.1002/adfm.201401696
    Journal articles | 2015
    Lord MS; Farrugia BL; Rnjak-Kovacina J; Whitelock JM, 2015, 'Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix', Expert Review of Molecular Diagnostics, 15, pp. 77 - 95, http://dx.doi.org/10.1586/14737159.2015.979158
    Journal articles | 2015
    Shawky MS; Ricciardelli C; Lord M; Whitelock J; Ferro V; Britt K; Thompson EW, 2015, 'Proteoglycans: Potential Agents in Mammographic Density and the Associated Breast Cancer Risk', Journal of Mammary Gland Biology and Neoplasia, 20, pp. 121 - 131, http://dx.doi.org/10.1007/s10911-015-9346-z
    Journal articles | 2015
    Farrugia BL; Lord MS; Melrose J; Whitelock JM, 2015, 'Can we produce heparin/heparan sulfate biomimetics using "mother-nature" as the gold standard?', , http://dx.doi.org/10.3390/molecules20034254
    Journal articles | 2014
    Chang T; Lord MS; Bergmann B; MacMillan A; Stenzel MH, 2014, 'Size effects of self-assembled block copolymer spherical micelles and vesicles on cellular uptake in human colon carcinoma cells', Journal of Materials Chemistry B, 2, pp. 2883 - 2891, http://dx.doi.org/10.1039/c3tb21751e
    Journal articles | 2014
    Lord MS; Jung MS; Cheng B; Whitelock JM, 2014, 'Transcriptional complexity of the HSPG2 gene in the human mast cell line, HMC-1', Matrix Biology, 35, pp. 123 - 131, http://dx.doi.org/10.1016/j.matbio.2013.12.005
    Journal articles | 2014
    Lord MS; Tsoi BM; Farrugia BL; Simon Ting SR; Baker S; Wiesmann WP; Whitelock JM, 2014, 'Synthesis and characterization of water soluble biomimetic chitosans for bone and cartilage tissue regeneration', Journal of Materials Chemistry B, 20, pp. 6517 - 6526, http://dx.doi.org/10.1039/c4tb00531g
    Journal articles | 2014
    Lord MS; Whitelock JM; Simmons A; Williams RL; Milthorpe BK, 2014, 'Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography', Biointerphases, 9, pp. 041002, http://dx.doi.org/10.1116/1.4900993
    Journal articles | 2014
    2014, 'Bioengineered heparin: Is there a future for this form of the successful therapeutic?', Bioengineered, 5, pp. 222 - 226, http://dx.doi.org/10.4161/bioe.29388
    Journal articles | 2014
    2014, 'The localisation of inflammatory cells and expression of associated proteoglycans in response to implanted chitosan', , http://dx.doi.org/10.1016/j.biomaterials.2013.10.068
    Journal articles | 2014
    2014, 'The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling', , http://dx.doi.org/10.1016/j.matbio.2014.01.016
    Journal articles | 2013
    Jung M; Lord MS; Cheng B; Lyons JG; Alkouri H; Hughes M; McCarthy S; Iozzo R; Whitelock J, 2013, 'Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: A role in angiogenesis and wound healing', The Journal of Biological Chemistry, 288, pp. 3289 - 3304, http://dx.doi.org/10.1074/jbc.M112.387811
    Journal articles | 2013
    Lord MS; Day AJ; Youssef P; Zhuo L; Watanabe H; Caterson B; Whitelock J, 2013, 'Sulfation of the bikunin chondroitin sulfate chain determines heavy chain-hyaluronan complex formation', The Journal of Biological Chemistry, 288, pp. 11941 - 22930, http://dx.doi.org/10.1074/jbc.M112.404186
    Journal articles | 2013
    Lord MS; Whitelock J, 2013, 'Recombinant production of proteoglycans and their bioactive domains', FEBS Journal, 280, pp. 2490 - 2510, http://dx.doi.org/10.1111/febs.12197
    Journal articles | 2013
    Reyes-ortega F; Rodriguez G; Aguilar MR; Lord MS; Whitelock J; Stenzel MH; San Roman J, 2013, 'Encapsulation of low molecular weight heparin (bemiparin) into polymeric nanoparticles obtained from cationic block copolymers: Properties and cell activity', Journal of Materials Chemistry, 1, pp. 850 - 860
    Journal articles | 2013
    Ting SRS; Whitelock J; Tomic R; Gunawan C; Teoh WY; Amal R; Lord MS, 2013, 'Cellular uptake and activity of heparin functionalised cerium oxide nanoparticles in monocytes', Biomaterials, 34, pp. 4377 - 4386, http://dx.doi.org/10.1016/j.biomaterials.2013.02.042
    Journal articles | 2013
    Zhao Y; Lord MS; Stenzel MH, 2013, 'A polyion complex micelle with heparin for growth factor delivery and uptake into cells', Journal of Materials Chemistry, 1, pp. 1635 - 1643
    Journal articles | 2013
    2013, 'Anti-Angiogenic Activity of Heparin Functionalised Cerium Oxide Nanoparticles', , http://dx.doi.org/10.1016/j.biomaterials.2013.07.083
    Journal articles | 2012
    Chrzanowski W; Kondyurin A; Lee JH; Lord MS; Bilek MMM; Kim H-W, 2012, 'Biointerface: protein enhanced stem cells binding to implant surface', Journal of Materials Science - Materials in Medicine, 23, pp. 2203 - 2215, http://dx.doi.org/10.1007/s10856-012-4687-2
    Journal articles | 2012
    Chuang CY; Shahin K; Lord MS; Melrose J; Doran PM; Whitelock J, 2012, 'The cartilage matrix molecule components produced by human foetal cartilage rudiment cells within scaffolds and the role of exogenous growth factors', Biomaterials, 33, pp. 4078 - 4088, http://dx.doi.org/10.1016/j.biomaterials.2012.02.032
    Journal articles | 2012
    Lord MS; Estrella RP; Chuang CY; Youssef P; Karlsson NG; Flannery CR; Whitelock J, 2012, 'Not all lubricin isoforms are substituted with a glycosaminoglycan chain', Connective Tissue Research, 53, pp. 132 - 141, http://dx.doi.org/10.3109/03008207.2011.614364
    Journal articles | 2012
    Lord MS; Jung M; Teoh WY; Gunawan C; Vassie JA; Amal R; Whitelock J, 2012, 'Cellular uptake and reactive oxygen species modulation of cerium oxide nanoparticles in human monocyte cell line U937', Biomaterials, 33, pp. 7915 - 7924, http://dx.doi.org/10.1016/j.biomaterials.2012.07.024
    Journal articles | 2012
    2012, 'Perlecan domain 1 recombinant proteoglycan augments BMP-2 activity and osteogenesis', , http://dx.doi.org/10.1186/1472-6750-12-60
    Journal articles | 2011
    Hayes AJ; Lord MS; Smith SM; Smith MM; Whitelock JM; Weiss AS; Melrose J, 2011, 'Colocalization in vivo and association in vitro of perlecan and elastin', Histochemistry and Cell Biology, 136, pp. 437 - 454, http://dx.doi.org/10.1007/s00418-011-0854-7
    Journal articles | 2011
    Inglis D; Lord MS; Nordon R, 2011, 'Scaling deterministic lateral displacement arrays for high throughput and dilution-free enrichment of leukocytes', Journal of Micromechanics and Microengineering, 21, pp. 054024, http://dx.doi.org/10.1088/0960-1317/21/5/054024
    Journal articles | 2011
    Lord MS; Cheng B; McCarthy S; Jung M; Whitelock J, 2011, 'The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins', Biomaterials, 32, pp. 6655 - 6662, http://dx.doi.org/10.1016/j.biomaterials.2011.05.062
    Journal articles | 2010
    Chuang CY; Lord MS; Melrose J; Rees MD; Knox SM; Freeman C; Iozzo R; Whitelock J, 2010, 'Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan', Biochemistry, 49, pp. 5524 - 5532, http://dx.doi.org/10.1021/bi1005199
    Journal articles | 2010
    Holst J; Watson S; Lord MS; Eamegdool SS; Bax DV; Nivison-Smith LB; Kondyurin A; Ma L; Overhauser AF; Weiss AS; Rasko JEJ, 2010, 'Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells', Nature Biotechnology, 28, pp. 1123 - 1130, http://dx.doi.org/10.1038/nbt.1687
    Journal articles | 2010
    Lord MS; Foss M; Besenbacher F, 2010, 'Influence of nanoscale surface topography on protein adsorption and cellular response', Nano Today, 5, pp. 66 - 78, http://dx.doi.org/10.1016/j.nantod.2010.01.001
    Journal articles | 2009
    Lord MS; Pasqui D; Barbucci R; Milthorpe BK, 2009, 'Protein adsorption on derivatives of hyaluronic acid and subsequent cellular response', Journal of Biomedical Materials Research Part A, 91, pp. 635 - 646, http://dx.doi.org/10.1002/jbm.a.32219
    Journal articles | 2009
    Lord MS; Yu W; Cheng B; Simmons A; Poole-Warren LA; Whitelock J, 2009, 'The modulation of platelet and endothelial cell adhesion to vascular graft materials by perlecan', Biomaterials, 30, pp. 4898 - 4906, http://dx.doi.org/10.1016/j.biomaterials.2009.05.063
    Journal articles | 2008
    Lord MS; Modin C; Foss M; Duch M; Simmons A; Pedersen F; Besenbacher F; Milthorpe BK, 2008, 'Extracellular matrix remodelling during cell adhesion monitored by the quartz crystal microbalance', Biomaterials, 29, pp. 2581 - 2587, http://dx.doi.org/10.1016/j.biomaterials.2008.03.002
    Journal articles | 2008
    Whitelock J; Ma J; Davies NP; Nielsen N; Chuang CY; Rees MR; Iozzo R; Knox SM; Lord MS, 2008, 'Recombinant heparan sulfate for use in tissue engineering applications', Journal of Chemical Technology and Biotechnology, 83, pp. 496 - 504, http://dx.doi.org/10.1002/jctb.1835
    Journal articles | 2006
    Lord MS; Cousins B; Doherty P; Whitelock J; Simmons A; Williams R; Milthorpe BK, 2006, 'The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response', Biomaterials, 27, pp. 4856 - 4862, http://dx.doi.org/10.1016/j.biomaterials.2006.05.037
    Journal articles | 2006
    Lord MS; Modin C; Foss M; Duch M; Simmons A; Pedersen F; Milthorpe BK; Besenbacher F, 2006, 'Monitoring cell adhesion on tantalum and oxidised polystyrene using a quartz crystal microbalance with dissipation', Biomaterials, 27, pp. 4529 - 4537
    Journal articles | 2006
    Lord MS; Stenzel M; Simmons A; Milthorpe BK, 2006, 'Lysozyme interaction with poly(HEMA)-based hydrogel', Biomaterials, 27, pp. 1341 - 1345, http://dx.doi.org/10.1016/j.biomaterials.2005.09.007
    Journal articles | 2006
    Lord MS; Stenzel M; Simmons A; Milthorpe BK, 2006, 'The effect of charged groups on protein interactions with poly(HEMA) hydrogels', Biomaterials, 27, pp. 567 - 575, http://dx.doi.org/10.1016/j.biomaterials.2005.06.010
    Journal articles | 2006
    Melrose J; Roughley P; Knox SM; Smith S; Lord MS; Whitelock J, 2006, 'The structure, location and function of perlecan, a prominent pericellular proteoglycan of foetal, postnatal and mature hyaline cartilages', The Journal of Biological Chemistry, 281, pp. 36905 - 36914, http://dx.doi.org/10.1074/jbc.M608462200
  • Preprints | 2023
    Adhikari A; Abayasingam A; A NB; Kim HN; Lord M; Agapiou D; Maher L; Rodrigo C; Lloyd A; Bull R; Tedla N, 2023, Characterisation of antibody dependent cellular phagocytosis in patients infected with Hepatitis C virus with different clinical outcomes, , http://dx.doi.org/10.22541/au.168992839.95818489/v1
    Conference Papers | 2022
    Joukhdar H; Och Z; Hien T; Hebenton S; Lim K; Lord M; Rnjak-Kovacina J, 2022, 'Development of a simple multi-functional unidirectional freezing platform to engineer aligned scaffolds for tissue engineering', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, SOUTH KOREA, Jeju, pp. 714 - 714, presented at Tissue-Engineering-and-Regenerative-Medicine-International-Society-Asia-Pacific-Chapter Conference (TERMIS-AP), SOUTH KOREA, Jeju, 05 October 2022 - 08 October 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000899413100671&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    Johnson BB; Holmes TL; Thompson JL; Lord M; Denning C; Whitelock J; Merry CLR; Smith J, 2021, 'A CRISPR/Cas9 in vitro human-induced pluripotent stem cell (hiPSC) model to investigate the role of perlecan in cardiovascular fibrotic disease', in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, WILEY, Vol. 102, pp. 126 - 127, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000630872200029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2021
    Lord MS; Berret JF; Singh S; Vinu A; Karakoti AS, 2021, Redox Active Cerium Oxide Nanoparticles: Current Status and Burning Issues, , http://dx.doi.org/10.48550/arxiv.2106.06473
    Conference Abstracts | 2018
    Elgundi Z; Freelander A; Bean P; Whitelock J; Lord M, 2018, 'Investigating the roles of perlecan using antibodies with unique epitopes', in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, WILEY, ENGLAND, Manchester, Vol. 99, pp. A23 - A23, presented at Matrix Biology Europe Meeting, ENGLAND, Manchester, 21 July 2018 - 24 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000459467900046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Johnson L; Farrugia B; Whitelock J; Marks DC; Irving DO; Lord M, 2018, 'Biomimetic Surface Modification of PVC Platelet Bags to Improve Platelet Storage', in TRANSFUSION, WILEY, MA, Boston, Vol. 58, pp. 147A - 147A, presented at AABB Annual Meeting, MA, Boston, 13 October 2018 - 16 October 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000444475900342&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Smith J; Merry C; Lord M; Denning C; Whitelock J, 2018, 'Developing an in vitro human induced pluripotent stem cell (hiPSC) model using CRISPR/Cas9 to investigate the role of perlecan in fibrosis', in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, WILEY, ENGLAND, Manchester, Vol. 99, pp. A20 - A21, presented at Matrix Biology Europe Meeting, ENGLAND, Manchester, 21 July 2018 - 24 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000459467900041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Tedla N; An H; Fath T; Lord M; Bryant K, 2017, 'Leukocyte immunoglobulin-like receptor A3 (LILRA3) displays anti-inflammatory and neuro-regenerative functions through interaction with multiple ligands', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, DC, Washington, presented at Annual Meeting of the American-Association-of-Immunologists (AAI), DC, Washington, 12 May 2017 - 16 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407757000578&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Farrugia BL; Whitelock J; LORD M, 2016, 'The inflammatory response to implanted materials, fibrous capsule characterisation', in Front. Bioeng. Biotechnol., presented at 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016., http://dx.doi.org/10.3389/conf.FBIOE.2016.01.00994
    Conference Abstracts | 2016
    Farrugia BL; Whitelock J; Lord M, 2016, 'CHITOSAN SULPHATE: ENGINEERING A BIOMIMETIC GROWTH FACTOR DELIVERY SYSTEM', in Wound Repair and Regeneration, Wiley, Melbourne, Australia, Vol. 24, pp. A13 - A30, presented at Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia, 07 November 2016 - 09 November 2016, http://dx.doi.org/10.1111/wrr.12489
    Conference Abstracts | 2016
    Farrugia BL; whitelock J; LORD M, 2016, 'Chitosan sulfate: engineering a biomimetic growth factor delivery system', in Front. Bioeng. Biotechnol., Frontiers, Vol. 4, pp. A18 - A18, presented at 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016, http://dx.doi.org/10.3389/conf.fbioe.2016.01.01019
    Conference Abstracts | 2016
    Lord M; Whitelock J; Cheng B; Tang F; Lyons G, 2016, 'Bioengineering of human heparin: A next generation anti-coagulant', in The FASEB Journal, Federation of American Society of Experimental Biology (FASEB), San Diego, Vol. 30, pp. 1070.5 - 1070.5, presented at Experimental Biology 2016 Meeting, San Diego, 02 April 2016 - 06 April 2016, http://dx.doi.org/10.1096/fasebj.30.1_supplement.1070.5
    Conference Abstracts | 2016
    Lord M; chuang C; rnjak-kovacina J; cheng B; lyons G; whitelock J, 2016, 'Bioengineering proteoglycan-based matrices for blood contacting applications', in The FASEB Journal, Federation of American Society of Experimental Biology (FASEB), San Diego, Vol. 6, pp. 622.2 - 622.2, presented at Experimental Biology 2016, San Diego, 02 April 2016 - 06 April 2016
    Conference Papers | 2016
    Palmer JC; Lord MS; Pinyon JL; Wise AK; Lovell NH; Carter PM; Enke YL; Housley GD; Green RA, 2016, 'Understanding the cochlear implant environment by mapping perilymph proteomes from different species', in Patton J; Barbieri R; Ji J; Jabbari E; Dokos S; Mukkamala R; Guiraud D; Jovanov E; Dhaher Y; Panescu D; Vangils M; Wheeler B; Dhawan AP (eds.), Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers (IEEE), FL, Orlando, pp. 5237 - 5240, presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), FL, Orlando, 16 August 2016 - 20 August 2016, http://dx.doi.org/10.1109/embc.2016.7591908
    Conference Abstracts | 2016
    Rnjak-Kovacina J; Tang F; Whitelock JM; Lord MS, 2016, 'Domain V of Perlecan Covalently Immobilized on Silk Biomaterials Modulates Endothelial Cell and Platelet Interactions for Vascular Applications', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, CA, San Diego, Vol. 22, pp. S20 - S21, presented at TERMIS - Americas Conference and Exhibition, CA, San Diego, 11 December 2016 - 14 December 2016
    Conference Abstracts | 2016
    Tang F; Lau K; Kondyurin A; Lord MS; Whitelock JM; Bilek MM; Rnjak-Kovacina J, 2016, 'Plasma Immersion Ion Implantation Treatment of Silk Biomaterials Enhances Biological Function'
    Conference Abstracts | 2015
    Gunatillake T; Chui A; Lord M; Whitelock J; Murthi P; Ignatovic V; Monagle P; Brennecke S; Said J, 2015, '[289-POS]: Placental heparan sulphate glycosaminoglycans in pre-eclampsia.', http://dx.doi.org/10.1016/j.preghy.2014.10.295
    Conference Abstracts | 2014
    Whitelock J; Jung M; Cheng B; Lord M, 2014, 'Transcriptional regulation and proteolytic processing of perlecan in mast cells lead to the production of forms that contain the alpha2/beta1 integrin binding site: roles in wound healing and tissue regeneration', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, San Diego, Vol. 28, presented at Experimental Biology Meeting, CA, San Diego, 26 April 2014 - 30 April 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346646701331&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Langtry TN; Giokaris P; Milthorpe BK; Lord MS, 2013, 'Parameter estimation for a model of fibronectin adsorption onto hydroxylapatite, oxidised polystyrene and nanostructured silica', in Roberts AJ (ed.), ANZIAM Journal, pp. C429 - C445, http://journal.austms.org.au/ojs/index.php/ANZIAMJ/article/view/6326
    Conference Abstracts | 2012
    Jung M; Lord M; Cheng B; Lyons J; McCarthy S; Iozzo R; Whitelock J, 2012, 'MAST CELLS PRODUCE SHORTER FORMS OF PERLECAN THAT CONTAIN ENDOREPELLIN AND PROMOTE TISSUE FIBROSIS', in WOUND REPAIR AND REGENERATION, WILEY-BLACKWELL, Vol. 20, pp. A69 - A69, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308945000066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2012
    Jung M; Lord M; Cheng B; Lyons JG; Alkhouri H; Hughes JM; McCarthy S; Iozzo R; Whitelock J, 2012, 'Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: A role in angiogenesis and wound healing', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, Vol. 22, pp. 1627 - 1628, presented at Joint Meeting of the Society-for-Glycobiology and American-Society-for-Matrix-Biology, CA, San Diego, 11 November 2012 - 14 November 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310368700326&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2012
    Lord M; Day A; Youssef P; Zhuo L; Watanabe H; Caterson B; Whitelock J, 2012, 'Chondroitin sulfate-mediated stabilization of hyaluronan-rich matrices', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, Vol. 22, pp. 1627 - 1627, presented at Joint Meeting of the Society-for-Glycobiology and American-Society-for-Matrix-Biology, CA, San Diego, 11 November 2012 - 14 November 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310368700324&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2012
    Penm S; Lord M; O'Grady R; Whitelock J, 2012, 'Expression of matrix components in liver cells: Studies in human hepatocytes (HepG2) and hepatic stellate cells (LX-2)', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, Vol. 22, pp. 1546 - 1547, presented at Joint Meeting of the Society-for-Glycobiology and American-Society-for-Matrix-Biology, CA, San Diego, 11 November 2012 - 14 November 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310368700089&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2012
    Penm S; Lord MS; O'Grady R; Whitelock J, 2012, 'Expression of matrix components in liver cells: Studies in human hepatocytes (HepG2) and hepatic stellate cells (LX-2)', in Glycobiology, Vol. 22, pp. 1546 - 1547, http://dx.doi.org/10.1093/glycob/cws127
    Conference Abstracts | 2012
    Tang F; Lord M; Whitelock J, (ed.), 2012, 'The roles of melanoma-associated protein (CSPG4) and perlecan (HSPG2) in cancer, potential targets for drug therapy', in Glycobiology, Vol. 22, pp. 1605 - 1605
    Conference Abstracts | 2012
    Whitelock JM; Jung MS; Chuang CY; Cheng B; Koo T; Lyons JG; Lord MS, 2012, 'Shorter forms of the proteoglycan, Perlecan; Adding complexity to an already complex molecule', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, San Diego, Vol. 26, presented at Experimental Biology Meeting, CA, San Diego, 21 April 2012 - 25 April 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310711305959&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2011
    Lord MS; Jung M; Cheng B; McCarthy S; McGrath B; Whitelock J, 2011, 'Chitosan modulates wound healing events through interactions with platelets and mast cells', presented at The Australasian Society for Biomaterials and Tissue Engineering, Queenstown, 26 April 2011 - 30 April 2011
    Conference Abstracts | 2010
    Whitelock J; Jung MS; McCarthy S; So R; Lord M, 2010, 'ENZYMATIC PROCESSING OF EXTRACELLULAR MATRIX HEPARAN SULFATE PROTEOGLYCANS IN WOUND HEALING: A ROLE FOR MAST CELLS?', in WOUND REPAIR AND REGENERATION, WILEY-BLACKWELL, Vol. 18, pp. A61 - A61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000279454700012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2008
    Lord M; Ma J; Davies N; Chuang C; Nielsen N; Iozzo R; Whitelock J, 2008, 'Modulation of biosignalling using recombinant heparan sulfate', in 8th World Biomaterials Congress 2008, Vol. 3, pp. 1237
    Conference Papers | 2008
    Lord MS; Pasqui D; Barbucci R; Milthorpe BK, 2008, 'Protein adsorption on derivatives of hyaluronan', in Macromolecular Symposia, Wiley-V C H Verlag Gmbh, pp. 17 - 22
    Conference Abstracts | 2008
    Milthorpe B; Lord M; Simmons A, 2008, 'Cell-material interactions from modeling QCM-D data', in 8th World Biomaterials Congress 2008, Vol. 3, pp. 1236
    Conference Papers | 2005
    Lord MS; Modin C; Foss M; Duch M; Simmons A; Besenbacher F; Milthorpe BK, 2005, 'Investigation of cellular interactions with surfaces using the quartz crystal microbalance (QCM-D)', in x (ed.), Proceedings of the 7th International Conference of Cellular Engineering, pp. 70 - 73, presented at 7th International Conference of Cellular Engineering, -
    Conference Abstracts | 2004
    Lord MS; Milthorpe BK, 2004, 'A quartz crystal microbalance study of biomolecular adsorption on polymer films', in Transactions - 7th World Biomaterials Congress, pp. 1378
    Conference Abstracts | 2004
    (eds.), 2004, 'Transactions of the 7th World Biomaterials Congress', Sydney, presented at Transactions of the 7th World Biomaterials Congress, Sydney
    Conference Abstracts | 2003
    (ed.), 2003, '18th European Conference on Biomaterials', Stuttgart, Germany, presented at 18th European Conference on Biomaterials, Stuttgart, Germany

 

ARC Future Fellowship (2022-2026) Engineering nanomaterial interactions with the cell surface.
ARC Linkage Project with Synedgen Inc (2020-2023) Understanding glycopolymer interactions with the extracellular matrix.
Diabetes Australia General Grant (2019) Bioengineered growth factor binding scaffolds.
ARC  Linkage Infrastructure, Equipment and Facilities (2019) Advanced mechanical property testing suite.
ARC Discovery Project (2015-2019) Novel biomimetic vascular biomaterials using extracellular matrix molecules.
ARC Linkage Project with the Australian Red Cross Blood Service (2014-2019) Biomimetic blood bag materials for prolonged platelet storage.
ARC Linkage Project with Cochlear Ltd (2014-2018) Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes.
National Heart Foundation (2011-2012) The roles of perlecan heparan sulphate in modulating vascular intimal hyperplasia.
ARC Linkage Project with Synedgen Inc (including Australian Postdoctoral Fellowship) (2010-2014) Targeted growth factor delivery using natural polysaccharide materials for bone regeneration.
ARC Discovery Project (2010-2013) Advanced nanoparticles as biocompatible antioxidant agents with targeting functionality.
ARC Linkage Project with HemCon Medical Technologies (2007-2010) Blood component interactions with polysaccharide biomaterials for vascular applications.

In addition, Professor Lord has been awarded grant funding from UNSW through the Research Infrastructure Scheme, Career Advancement Fund, Faculty of Engineering Carers Award, Faculty of Engineering Early Career Researcher fund and School project support.

Selected:
UNSW Vice-Chancellor's Award for Excellence in Higher Degree Research Leadership recognised leadership creating a new initiative for higher degree research candidates (2023)
Barry Preston Award from the Matrix Biology Society of Australia and New Zealand recognised leadership in the field of matrix biology distinguished by a sustained record of achievement, commitment to mentoring junior researchers and exceptional communication skills (2022)
UNSW Faculty of Engineering Excellence in Leadership award (2020)
Matrix Biology Society of Australia and New Zealand Paper of the Month and Year Award (2020) - Mid-career category
NSW Young Tall Poppy Science Award in recognition of the achievements of Australia’s outstanding young scientific researchers and communicators. (2014)
UNSW Emeritus Professor Maria Skyllas-Kazacos Young Professional Award for Outstanding Achievement Award for female alumni from UNSW Engineering in recognition of a significant achievement in their field. (2013)
New Investigator Award from the Matrix Biology Society of Australia and New Zealand recognised the research achievements of early career researchers in the field of matrix biology with less than 10 years post-doctoral experience. (2008)
 

Designing next-generation nanomaterials. I develop models to study biomaterial interactions with cells replicating the cell surface in vivo. This research is enabling the design of biomaterials for controlled interactions with cells including efficient intracellular delivery, overcoming the current and critical challenges to widespread use in therapies, drug delivery, diagnostics and cell technologies.

Engineering biomaterials for tissue regeneration. I develop biomaterial scaffolds that encourage the formation of new blood vessels overcoming challenges in current approaches associated with high manufacturing cost and off-target effects.

University leadership

  • Academic Director, Australian Graduate School of Engineering Industry PhD Program, Faculty of Engineering
  • Academic Director, Molecular Surface Interaction Laboratory, Mark Wainwright Analytical Centre

Professional leadership

  • Past President, Matrix Biology Society of Australia and New Zealand (since 2022) President (2019-2021)
  • Member, Standards Australia Committee HE-030 Biological and Clinical Evaluation of Medical Devices which reviews and ratifies ISO109993 and TC194, the international standard that evaluates the biocompatibility of medical devices and manages biological risk.
  • Council Member, International Society for Matrix Biology
  • Member, Australasian Society for Biomaterials and Tissue Engineering

Editorial positions

  • Editorial Board, Cellular Signalling
  • Associate Editor, IEEE Engineering in Medicine and Biology Society Conference Proceedings

My Research Supervision

Lecturers

 

Post-doctoral Research Fellows

 

Current PhD/MPhil Candidates

  • Claire BridgesExploring glycopolymer interactions with blood vessels in diabetic conditions
  • Habib JoukhdarSilk fibroin as a biomaterial for cardiac patches
  • James Paoloni, Design of RNA drug delivery systems targeting the endothelium
  • Dan Wang, The interplay between cell morphology and glycocalyx structure and function

 

PhD/MPhil alumni (selected)

 

 

My Teaching

Cellular and Tissue Engineering (BIOM9333)
Research Thesis (BIOM4951/4952/4953)
Research Thesis Biomedical Engineering (BIOM9020/9021)
Medical Biotechnology (BABS3061)