Dr Michael Cardamone

Dr Michael Cardamone

Conjoint Senior Lecturer


Medicine & Health
School of Clinical Medicine

Dr Michael Cardamone is a Conjoint Senior Lecturer at UNSW Medicine School of Women’s and Children’s Health.

Dr Cardamone is also a Senior staff specialist and Paediatric neurologist at the Department of Neurology at Sydney Children’s Hospital Network in Randwick.

Dr Cardamone is currently the lead clinician of the ketogenic diet service and he is also administrative head of the video EEG/telemetry unit of SCH in addition to running epilepsy and general neurology clinics at the hospital.

He is one of the local examiners at SCH for the RACP clinical examinations for Paediatrics and Child Health.  

During his epilepsy fellowship at SCH, he studied the use of mTOR inhibitors such as rapamycin for the use of epilepsy in children with Tuberous Sclerosis Complex.

He was the Uncle Bob’s Neurology Fellow at RCH in Melbourne where he conducted research on Arterial Ischaemic stroke in children with cardiac disease. He then continued his training in Neurology at St Vincent’s Hospital in Melbourne gaining experience in MS, epilepsy, stroke medicine and general neurology.  He then spent a year at the Murdoch at RCH Melbourne where he was the metabolic fellow treating children with neurometabolic disorders.  

02 9382 1847
Sydney Children's Hospital High Street Randwick NSW 2013
  • Journal articles | 2023
    Briest RC; Cheung AK; Kandula T; Cardamone M; Pillai SC; Sampaio H; Teoh HL; Webster RI; Wenderoth J; Andrews PI, 2023, 'Urgent computed tomography angiography in paediatric stroke', Developmental Medicine and Child Neurology, 65, pp. 126 - 135, http://dx.doi.org/10.1111/dmcn.15285
    Journal articles | 2023
    Forwood C; Ashton K; Zhu Y; Zhang F; Dias KR; Standen K; Evans CA; Carey L; Cardamone M; Shalhoub C; Katf H; Riveros C; Hsieh TC; Krawitz P; Robinson PN; Dudding-Byth T; Sadikovic B; Pinner J; Buckley MF; Roscioli T, 2023, 'Integration of EpiSign, facial phenotyping, and likelihood ratio interpretation of clinical abnormalities in the re-classification of an ARID1B missense variant', American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, http://dx.doi.org/10.1002/ajmg.c.32056
    Journal articles | 2023
    Hosie PH; Lim C; Scott TRD; Cardamone M; Farrar MA; Frith C; Andrews PI; Pinner J; Pillai S, 2023, 'Treatment of severe acute necrotizing encephalopathy of childhood with interleukin-6 receptor blockade in the first 24 h as add-on immunotherapy shows favorable long-term outcome at 2 years', Brain and Development, 45, pp. 401 - 407, http://dx.doi.org/10.1016/j.braindev.2023.03.002
    Journal articles | 2023
    Oliver KL; Trivisano M; Mandelstam SA; De Dominicis A; Francis DI; Green TE; Muir AM; Chowdhary A; Hertzberg C; Goldhahn K; Metreau J; Prager C; Pinner J; Cardamone M; Myers KA; Leventer RJ; Lesca G; Bahlo M; Hildebrand MS; Mefford HC; Kaindl AM; Specchio N; Scheffer IE, 2023, 'WWOX developmental and epileptic encephalopathy: Understanding the epileptology and the mortality risk', Epilepsia, 64, pp. 1351 - 1367, http://dx.doi.org/10.1111/epi.17542
    Journal articles | 2023
    Scheffer IE; Bennett CA; Gill D; de Silva MG; Boggs K; Marum J; Baker N; Palmer EE; Howell KB; Andrews I; Antony J; Ardern-Holmes S; Bye AM; Cardamone M; Chelakkadan S; Clark D; Curnow SR; Dabscheck G; Fahey MC; Freeman JL; Gupta S; Harvey AS; Hildebrand MS; Inder M; Kanhangad M; Kornberg AJ; Kothur K; Lawson JA; Leventer RJ; Malone S; Menezes MP; Mohammad S; Nagarajan L; Pillai S; Pridmore C; Procopis PG; Sampaio H; Silberstein J; Sinclair A; Smith N; Subramanian G; Troedson C; Ware T; White SM, 2023, 'Exome sequencing for patients with developmental and epileptic encephalopathies in clinical practice', Developmental Medicine and Child Neurology, 65, pp. 50 - 57, http://dx.doi.org/10.1111/dmcn.15308
    Journal articles | 2022
    Uppal P; Cardamone M; Fonseca B; Briggs N; A Lawson J, 2022, 'The need for improved management of status epilepticus in children in Australia: Time from seizure onset to treatment is consistently delayed', Journal of Paediatrics and Child Health, 58, pp. 261 - 266, http://dx.doi.org/10.1111/jpc.15697
    Journal articles | 2021
    Palmer EE; Sachdev R; Macintosh R; Melo US; Mundlos S; Righetti S; Kandula T; Minoche AE; Puttick C; Gayevskiy V; Hesson L; Idrisoglu S; Shoubridge C; Thai MHN; Davis RL; Drew AP; Sampaio H; Andrews PI; Lawson J; Cardamone M; Mowat D; Colley A; Kummerfeld S; Dinger ME; Cowley MJ; Roscioli T; Bye A; Kirk E, 2021, 'Diagnostic Yield of Whole Genome Sequencing After Nondiagnostic Exome Sequencing or Gene Panel in Developmental and Epileptic Encephalopathies', Neurology, 96, pp. E1770 - E1782, http://dx.doi.org/10.1212/WNL.0000000000011655
    Journal articles | 2020
    Macdonald-Laurs E; Wenderoth J; Cardamone M; Sampaio H; Andrews PI, 2020, 'Endovascular clot retrieval for acute ischaemic stroke due to basilar artery occlusion in childhood', Developmental Medicine and Child Neurology, 62, pp. 1221 - 1223, http://dx.doi.org/10.1111/dmcn.14449
    Journal articles | 2020
    Ngu F; Cardamone M; Wanaguru D; Currie B; Wegner EA; Andrews I; Haindl W, 2020, 'Medically resistant juvenile myasthenia gravis following thymectomy: Role for FDG PET/CT', Journal of Pediatric Surgery Case Reports, 59, http://dx.doi.org/10.1016/j.epsc.2020.101494
    Journal articles | 2019
    Banuelos R; Beavis E; Le Marne F; Rowe N; Gao Y; Menzies J; Farrar MA; Cardamone M, 2019, 'Factors Affecting the Efficacy, Tolerability and Compliance of Dietary Therapy for Epilepsy- Four-Years Experience', Neurological Case Reports, 2, pp. 1010 - 1010, http://www.remedypublications.com/neurological-case-reports-abstract.php?aid=4936
    Journal articles | 2019
    Uppal P; Cardamone M; Webber C; Briggs N; Lawson JA, 2019, 'Management of status epilepticus in children prior to medical retrieval: Deviations from the guidelines', Journal of Paediatrics and Child Health, 55, pp. 1458 - 1462, http://dx.doi.org/10.1111/jpc.14448
    Journal articles | 2018
    Chen KA; Farrar M; Cardamone M; Gill D; Smith R; Cowell CT; Truong L; Lawson JA, 2018, 'Cannabidiol for treating drug-resistant epilepsy in children: The New South Wales experience', Medical Journal of Australia, 209, pp. 217 - 221, http://dx.doi.org/10.5694/mja18.00023
    Journal articles | 2018
    Chen KA; Farrar MA; Cardamone M; Lawson J, 2018, 'Cannabis for paediatric epilepsy: challenges and conundrums', The Medical journal of Australia, 208, pp. 138 - 142, http://dx.doi.org/10.5694/mja17.00699
    Journal articles | 2018
    Gennarino VA; Palmer EE; McDonell LM; Wang L; Adamski CJ; Koire A; See L; Chen CA; Schaaf CP; Rosenfeld JA; Panzer JA; Moog U; Hao S; Bye A; Kirk EP; Stankiewicz P; Breman AM; McBride A; Kandula T; Dubbs HA; Macintosh R; Cardamone M; Zhu Y; Ying K; Dias KR; Cho MT; Henderson LB; Baskin B; Morris P; Tao J; Cowley MJ; Dinger ME; Roscioli T; Caluseriu O; Suchowersky O; Sachdev RK; Lichtarge O; Tang J; Boycott KM; Holder JL; Zoghbi HY, 2018, 'A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures', Cell, 172, pp. 924 - 936.e11, http://dx.doi.org/10.1016/j.cell.2018.02.006
    Journal articles | 2018
    Ho G; Carey K; Cardamone M; Farrar M, 2018, 'Myotonic dystrophy type 1: clinical manifestations in children and adolescents', Archives of Disease in Childhood, 104, pp. 48 - 52, http://dx.doi.org/10.1136/archdischild-2018-314837
    Journal articles | 2018
    Palmer EE; Schofield D; Shrestha R; Kandula T; Macintosh R; Lawson JA; Andrews I; Sampaio H; Johnson AM; Farrar MA; Cardamone M; Mowat D; Elakis G; Lo W; Zhu Y; Ying K; Morris P; Tao J; Dias KR; Buckley M; Dinger ME; Cowley MJ; Roscioli T; Kirk EP; Bye A; Sachdev RK, 2018, 'Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness', Molecular Genetics and Genomic Medicine, 6, pp. 186 - 199, http://dx.doi.org/10.1002/mgg3.355
    Journal articles | 2018
    Uppal P; Cardamone M; Lawson JA, 2018, 'Outcomes of deviation from treatment guidelines in status epilepticus: A systematic review', Seizure, 58, pp. 147 - 153, http://dx.doi.org/10.1016/j.seizure.2018.04.005
    Journal articles | 2017
    Asakai H; Stojanovski B; Galati JC; Zannino D; Cardamone M; Hutchinson D; Cheung MMH; Mackay MT, 2017, 'Risk Factors for Peri-Procedural Arterial Ischaemic Stroke in Children with Cardiac Disease', Pediatric Cardiology, 38, pp. 1385 - 1392, http://dx.doi.org/10.1007/s00246-017-1674-x
    Journal articles | 2017
    Ho G; Widger J; Cardamone M; Farrar MA, 2017, 'Quality of life and excessive daytime sleepiness in children and adolescents with myotonic dystrophy type 1', Sleep Medicine, 32, pp. 92 - 96, http://dx.doi.org/10.1016/j.sleep.2016.12.005
    Journal articles | 2016
    Farrar MA; Ho G; Widger J; Cardamone M, 2016, 'Quality of life and excessive daytime sleepiness in children and adolescents with Myotonic dystrophy type 1', Sleep Medicine, 32, pp. 92 - 96, http://dx.doi.org/10.1016/j.sleep.2016.12.005
    Journal articles | 2016
    Farrar MA; Teoh HL; Brammah S; Roscioli T; Cardamone M, 2016, 'Glial mitochondropathy in infantile neuroaxonal dystrophy: Pathophysiological and therapeutic implications', Brain, 139, pp. e67, http://dx.doi.org/10.1093/brain/aww174
    Journal articles | 2016
    Le Marne FA; McGinness H; Slade R; Cardamone M; Balbir Singh S; Connolly AM; Bye AME, 2016, 'Evaluation of an E-learning resource on approach to the first unprovoked seizure', Journal of Paediatrics and Child Health, 52, pp. 896 - 900, http://dx.doi.org/10.1111/jpc.13277
    Journal articles | 2015
    Asakai H; Stojanovski B; Galati JC; Cardamone M; Hutchinson D; Cheung MM; Mackay MT, 2015, 'Abstract T P375: Risk Factors for Peri-procedural Stroke in Children With Cardiac Disease', Stroke, 46, http://dx.doi.org/10.1161/str.46.suppl_1.tp375
    Journal articles | 2015
    Cardamone M; Asakai H; Hutchinson D; Stojanovski B; Galati JC; Cheung MMH; MacKay MT, 2015, 'Arterial ischemic stroke in children with cardiac disease', Neurology, 85, pp. 2053 - 2059, http://dx.doi.org/10.1212/WNL.0000000000002036
    Journal articles | 2015
    Ho G; Cardamone M; Farrar M, 2015, 'Congenital and childhood myotonic dystrophy: Current aspects of disease and future directions.', World J Clin Pediatr, 4, pp. 66 - 80, http://dx.doi.org/10.5409/wjcp.v4.i4.66
    Journal articles | 2015
    Palmer EE; Hayner J; Sachdev R; Cardamone M; Kandula T; Morris P; Dias KR; Tao J; Miller D; Zhu Y; Macintosh R; Dinger ME; Cowley MJ; Buckley MF; Roscioli T; Bye A; Kilberg MS; Kirk EP, 2015, 'Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine', Molecular Genetics and Metabolism, 116, pp. 178 - 186, http://dx.doi.org/10.1016/j.ymgme.2015.08.007
    Journal articles | 2015
    Wibisono C; Rowe N; Beavis E; Kepreotes H; Mackie FE; Lawson JA; Cardamone M, 2015, 'Ten-year single-center experience of the ketogenic diet: Factors influencing efficacy, tolerability, and compliance', Journal of Pediatrics, 166, pp. 1030 - 1036.e1, http://dx.doi.org/10.1016/j.jpeds.2014.12.018
    Journal articles | 2014
    Cardamone M; Flanagan D; Mowat D; Kennedy SE; Chopra M; Lawson JA, 2014, 'Mammalian target of rapamycin inhibitors for intractable epilepsy and subependymal giant cell astrocytomas in tuberous sclerosis complex', Journal of Pediatrics, 164, pp. 1195 - 1200, http://dx.doi.org/10.1016/j.jpeds.2013.12.053
    Journal articles | 2012
    Kamien BA; Cardamone DM; Lawson JA; Sachdev RR, 2012, 'A genetic diagnostic approach to infantile epileptic encephalopathies', Journal of Clinical Neuroscience, 19, pp. 934 - 941, http://dx.doi.org/10.1016/j.jocn.2012.01.017
    Journal articles | 2011
    Hutchinson D; Cheung M; Cardamone M; Mackay M; Barnes C; Coleman L, 2011, 'Arterial Ischaemic Stroke in Children with Heart Disease: Experience in a Single Centre Over 17 Years', Heart, Lung and Circulation, 20, pp. S233 - S234, http://dx.doi.org/10.1016/j.hlc.2011.05.574
    Journal articles | 2009
    Cardamone M; Hutchinson D; Cheung M; Coleman L; Mackay MT, 2009, '35. Preliminary findings: a retrospective study of ischaemic stroke in children with congenital and acquired cardiac disease', Journal of Clinical Neuroscience, 16, pp. 1536 - 1537, http://dx.doi.org/10.1016/j.jocn.2009.07.060
    Journal articles | 2008
    Cardamone M; Alex G; Harari MD; Moss WP; Oliver MR, 2008, 'Severe iron-deficiency anaemia in adolescents: Consider Helicobacter pylori infection', Journal of Paediatrics and Child Health, 44, pp. 647 - 650, http://dx.doi.org/10.1111/j.1440-1754.2008.01374.x
    Journal articles | 2008
    Cardamone M; Darras BT; Ryan MM, 2008, 'Inherited myopathies and muscular dystrophies', Seminars in Neurology, 28, pp. 250 - 259, http://dx.doi.org/10.1055/s-2008-1062269
    Journal articles | 1998
    Cardamone M; Lee RP; Lucas JC; Birks DVA; O'Donoghue M; Lofthouse SA; Brandon MR, 1998, 'Sustained-release delivery systems and their application for endoparasite control in animals', Journal of Controlled Release, 51, pp. 73 - 83, http://dx.doi.org/10.1016/S0168-3659(97)00160-0
    Journal articles | 1997
    Cardamone M; Lofthouse SA; Lucas JC; Lee RP; O'Donoghue M; Brandon MR, 1997, 'In vitro testing of a pulsatile delivery system and its in vivo application of immunisation against tetanus toxoid', Journal of Controlled Release, 47, pp. 205 - 219, http://dx.doi.org/10.1016/S0168-3659(97)01639-8
    Journal articles | 1995
    Cardamone M; Brandon MR; Puri NK, 1995, 'Comparing the Refolding and Reoxidation of Recombinant Porcine Growth Hormone from a Urea Denatured State and from Escherichia Coli Inclusion Bodies', Biochemistry, 34, pp. 5773 - 5794, http://dx.doi.org/10.1021/bi00017a009
    Journal articles | 1994
    Cardamone M; Degen T; O'Donoghue MF; Brandon MR, 1994, 'Development of a pulsatile drug delivery system for veterinary pharmaceuticals', Proceedings of the Controlled Release Society, pp. 833 - 834
    Journal articles | 1994
    Cardamone M; Puri NK; Sawyer WH; Capon RJ; Brandon MR, 1994, 'A spectroscopic and equilibrium binding analysis of cationic detergent-protein interactions using soluble and insoluble recombinant porcine growth hormone', Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, 1206, pp. 71 - 82, http://dx.doi.org/10.1016/0167-4838(94)90074-4
    Journal articles | 1993
    Cardamone M; Ashman K; Brandon MR; Puri NK, 1993, 'Identification of cysteine-containing peptides during the peptide mapping of recombinant proteins', Peptide Research, 6, pp. 242 - 248
    Journal articles | 1993
    Puri NK; Cardamone M; Crivelli E; Traeger JC, 1993, 'Characterization of a truncated form of recombinant porcine growth hormone generated in vitro during solubilization of inclusion bodies', Protein Expression and Purification, 4, pp. 164 - 175, http://dx.doi.org/10.1006/prep.1993.1023
    Journal articles | 1992
    Cardamone M; Puri NK, 1992, 'Spectrofluorimetric assessment of the surface hydrophobicity of proteins', Biochemical Journal, 282, pp. 589 - 593, http://dx.doi.org/10.1042/bj2820589
    Journal articles | 1992
    Puri NK; Cardamone M, 1992, 'A relationship between the starting secondary structure of recombinant porcine growth hormone solubilised from inclusion bodies and the yield of native (monomeric) protein after in vitro refolding', FEBS Letters, 305, pp. 177 - 180, http://dx.doi.org/10.1016/0014-5793(92)80661-Y
    Journal articles | 1992
    Purl NK; Crivelli E; Cardamone M; Fiddes R; Bertolini J; Ninham B; Brandon MR, 1992, 'Solubilization of growth hormone and other recombinant proteins from Escherichia coli inclusion bodies by using a cationic surfactant', Biochemical Journal, 285, pp. 871 - 879, http://dx.doi.org/10.1042/bj2850871
    Journal articles | 1991
    Crivelli E; Cardamone M; Puri NK, 1991, 'A single step method for the solubilization and refolding of recombinant protein from E. coli inclusion bodies.', Australian journal of biotechnology, 5, pp. 78 - 86
  • Conference Papers | 2017
    Uppal P; Cardamone M; Briggs N; Iawson J, 2017, 'Are we following the status epilepticus guidelines and does it matter?', in NEUROLOGY, LIPPINCOTT WILLIAMS & WILKINS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000577381503001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2016
    Farrar M; Ho G; Carey K; Cardamone M, 2016, 'Myotonic Dystrophy Type 1: Clinical manifestations in children and adolescents', Taiwan, presented at 15th Asian and Oceanic Myology Congress and Taiwanese Child Neurology Society Annual Scientific Meeting, Taiwan
    Conference Papers | 2012
    Cardamone M; Flanagan D; Mowat D; Kennedy S; Chopra M; Lawson JA, 2012, 'PRELIMINARY DATA ON THE USE OF MTOR INHIBITORS FOR MANAGEMENT OF REFRACTORY SEIZURES AND FOR THE MANAGEMENT OF SUBEPENDYMAL GIANT CELL ASTROCYTOMAS IN PATIENTS WITH TUBEROUS SCLEROSIS COMPLEX', in EPILEPSIA, WILEY-BLACKWELL, ENGLAND, London, pp. 42 - 42, presented at 10th European Congress on Epileptology, ENGLAND, London, 30 September 2012 - 04 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308875900142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Mackay M; Cardamone M; Hutchinson D; Barnes C; Coleman L; Cheung M, 2011, 'Arterial Ischaemic Stroke In Children With Heart Disease', in STROKE, LIPPINCOTT WILLIAMS & WILKINS, CA, Los Angeles, pp. E97 - E97, presented at International Stroke Conference, CA, Los Angeles, 08 February 2011 - 10 February 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287479400193&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1993

Currently involved in clinical trials of novel agents to treat medically resistant epilepsy in children.

Collaborating with researchers at CHW (Dr Wendy Gold) in the development of novel gene therapy techniques for WWOX related epileptic encephalopathy

Developing clinical practice guidelines for the treatment of epileptic seizures in infants and children

Collaborating with Westmead Hospital to determine the efficacy and safety of dietary therapies for adolescents and adults with genetic epilepsies.  

My Research Supervision

Masters by research : the application of source localisation methods for detecting the epileptogenic source in children with intractable focal epilepsy

PhD : The efficacy and safety of ketogenic diets in adolescents and adults with genetic epilepsies.