Professor Michelle   Haber
Conjoint Professor

Professor Michelle Haber

1984             PhD                                                                              University of New South Wales

1978-79       PhD qualifying program                                           University of New South Wales

1978             BSc (Psych) Honours Class 1, University Medal   University of New South Wales

2008             D.Sc. honaris causa                                                   University of New South Wales

 

medicine-health
Sch Women's&Children's Health

Professor Michelle Haber obtained her PhD at UNSW in 1984, and subsequently undertook postdoctoral studies at Hadassah Hebrew University, Israel and Albert Einstein College of Medicine, New York. She was appointed as the Director of the Children's Cancer Institute (CCI) in 2000, and then Executive Director in 2003, where she is the Co-Head of CCI’s Molecular Targets and Cancer Therapeutics Theme and also heads the Experimental Therapeutics Program. 

 Michelle’s research is focused on developing novel approaches to treating refractory childhood cancer through identifying molecular targets that drive cancer growth and development, developing new drugs to inhibit the action of these targets, and combining existing and new drug treatments into novel therapeutic approaches that can be rapidly translated into national and international clinical trials.

Phone
+61 2 7209 6709
Location
Children's Cancer Institute Lowy Cancer Research Centre, UNSW Australia PO Box 81 Randwick 2031 Australia

Publications

  • Book Chapters | 2014
    Professor Michelle Haber
    Fletcher J; Roundhill E; Haber M; Norris M, 2014, 'Clinical relevance of multidrug-resistance-proteins (MRPs) for anticancer drug resistance and prognosis', in Efferth T; Bonavida B (ed.), Resistancce to Targeted Anti-Cancer Therapeutics, Springer Press., pp. 27 - 52
    Book Chapters | 2013
    Professor Michelle Haber
    Cheung L; Murray JE; Norris MD; Haber M, 2013, 'Oncogene and Cancer - From Bench to Clinic', in Siregar YE; norris (ed.), Oncogene and Cancer - From Bench to Clinic, Inst za onkologiju i radiol, pp. 437 - 454, http://dx.doi.org/10.5772/54813
    Book Chapters | 2013
    Professor Michelle Haber
    Norris MD; Burkhart CA; Haber M; Gudkov AV; Nikiforov MA, 2013, 'Cell-Based Methods for the Identification of MYC-Inhibitory Small Molecules', in Soucek L; Sodir NM (ed.), The Myc Gene, edn. Methods in Molecular Biology, Humana Press Inc, pp. 255 - 264, http://dx.doi.org/10.1007/978-1-62703-429-6_18
    Book Chapters | 2012
    Professor Michelle Haber
    Fletcher JI; Haber M; Henderson M; Norris MD, 2012, 'Targeting Multidrug Resistance in Neuroblastoma', in Hayat MA (ed.), Pediatric Cancer Volume 1 Diagnosis, Therapy and Prognosis: Neuroblastoma, edn. Pediatric Cancer-Diagnosis Therapy and Prognosis, Springer, New York, USA, pp. 115 - 123, http://dx.doi.org/10.1007/978-94-007-2418-1_11
    Book Chapters | 2012
    Professor Michelle Haber
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2012, 'The Myc Gene: Methods and Protocols: Myc inhibitory molecules', in Methods in Molecular Biology, edn. Original, Humana Press
    Book Chapters | 2012
    Professor Michelle Haber
    Xue C; Gudkov A; Haber M; Norris MD, 2012, 'Small molecule drugs and targeted therapies for neuroblastoma', in Shimada H (ed.), Neuroblastoma - Present and Future, edn. First, In Tech, Croatia, pp. 299 - 324, http://www.amazon.com/Neuroblastoma-Present-and-Future-ebook/dp/B00CBWQI92/ref=sr_1_1?ie=UTF8&qid=1366940364&sr=8-1&keywords=neuroblastoma+-+present+and+future#reader_B00CBWQI92
    Book Chapters | 2000
    Professor Michelle Haber
    Haber M; Kavallaris M, 2000, 'Multidrug Resistance Genes in Neuroblastoma', in Neuroblastoma, edn. Original, Elsevier Science BV, Amsterdam, pp. 207 - 215
  • Journal articles | 2021
    Professor Michelle Haber
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Hayden E; Rouaen J; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Kankean A; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov A; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION IN DIPG', NEURO-ONCOLOGY, vol. 23, pp. 18 - 19, http://dx.doi.org/10.1093/neuonc/noab090.075
    Journal articles | 2021
    Professor Michelle Haber
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Joshi S; Rouaen JRC; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Tolhurst O; Kankean A; Hayden E; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov AV; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG', Cell Reports, vol. 35, pp. 108994 - 108994, http://dx.doi.org/10.1016/j.celrep.2021.108994
    Journal articles | 2021
    Professor Michelle Haber
    Xiao L; Somers K; Murray J; Pandher R; Karsa M; Ronca E; Bongers A; Terry R; Ehteda A; Gamble LD; Issaeva N; Leonova KI; O'Connor A; Mayoh C; Venkat P; Quek H; Brand J; Kusuma FK; Pettitt JA; Mosmann E; Kearns A; Eden G; Alfred S; Allan S; Zhai L; Kamili A; Gifford AJ; Carter DR; Henderson MJ; Fletcher JI; Marshall G; Johnstone RW; Cesare AJ; Ziegler DS; Gudkov AV; Gurova KV; Norris MD; Haber M, 2021, 'Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.', Clin Cancer Res, vol. 27, pp. 4338 - 4352, http://dx.doi.org/10.1158/1078-0432.CCR-20-2357
    Journal articles | 2021
    Professor Michelle Haber
    Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, vol. 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z
    Journal articles | 2021
    Professor Michelle Haber
    Karsa M; Kosciolek A; Bongers A; Mariana A; Failes T; Gifford AJ; Kees UR; Cheung LC; Kotecha RS; Arndt GM; Haber M; Norris MD; Sutton R; Lock RB; Henderson MJ; Somers K, 2021, 'Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin', British Journal of Cancer, vol. 125, pp. 55 - 64, http://dx.doi.org/10.1038/s41416-021-01332-x
    Journal articles | 2021
    Professor Michelle Haber
    Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, vol. 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906
    Journal articles | 2021
    Professor Michelle Haber
    Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, vol. 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044
    Journal articles | 2021
    Professor Michelle Haber
    Xiao L; Yeung H; Haber M; Norris MD; Somers K, 2021, 'Immunometabolism: A ‘Hot’ Switch for ‘Cold’ Pediatric Solid Tumors', Trends in Cancer, vol. 7, pp. 751 - 777, http://dx.doi.org/10.1016/j.trecan.2021.05.002
    Journal articles | 2021
    Professor Michelle Haber
    Cheung BB; Kleynhans A; Mittra R; Kim PY; Holien JK; Nagy Z; Ciampa OC; Seneviratne JA; Mayoh C; Raipuria M; Gadde S; Massudi H; Wong IPL; Tan O; Gong A; Suryano A; Diakiw SM; Liu B; Arndt GM; Liu T; Kumar N; Sangfelt O; Zhu S; Norris MD; Haber M; Carter DR; Parker MW; Marshall GM, 2021, 'A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma', Oncogene, vol. 40, pp. 2367 - 2381, http://dx.doi.org/10.1038/s41388-021-01712-w
    Journal articles | 2021
    Professor Michelle Haber
    Xie J; Kumar A; Dolman MEM; Mayoh C; Khuong-Quang DA; Cadiz R; Wong-Erasmus M; Mould EVA; Grebert-Wade D; Barahona P; Kamili A; Tsoli M; Failes TW; Chow SO; Bhatia K; Marshall GM; Ziegler DS; Haber M; Lock RB; Tyrrell V; Lau L; Athanasatos P; Gifford AJ, 2021, 'The important role of routine cytopathology in pediatric precision oncology', Cancer Cytopathology, http://dx.doi.org/10.1002/cncy.22448
    Journal articles | 2021
    Professor Michelle Haber
    Bӧhm JW; Sia KCS; Jones C; Evans K; Mariana A; Pang I; Failes T; Zhong L; Mayoh C; Landman R; Collins R; Erickson SW; Arndt G; Raftery MJ; Wilkins MR; Norris MD; Haber M; Marshall GM; Lock RB, 2021, 'Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia', Leukemia, http://dx.doi.org/10.1038/s41375-021-01248-8
    Journal articles | 2021
    Professor Michelle Haber
    Gamble LD; Purgato S; Henderson MJ; Di Giacomo S; Russell AJ; Pigini P; Murray J; Valli E; Milazzo G; Giorgi FM; Cowley M; Ashton LJ; Bhalshankar J; Schleiermacher G; Rihani A; Van Maerken T; Vandesompele J; Speleman F; Versteeg R; Koster J; Eggert A; Noguera R; Stallings RL; Tonini GP; Fong K; Vaksman Z; Diskin SJ; Maris JM; London WB; Marshall GM; Ziegler DS; Hogarty MD; Perini G; Norris MD; Haber M, 2021, 'A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma', Cancers, vol. 13, http://dx.doi.org/10.3390/cancers13081807
    Journal articles | 2021
    Professor Michelle Haber
    Grohmann C; Walker F; Devlin M; Luo MX; Chüeh AC; Doherty J; Vaillant F; Ho GY; Wakefield MJ; Weeden CE; Kamili A; Murray J; Po’uha ST; Weinstock J; Kane SR; Faux MC; Broekhuizen E; Zheng Y; Shield-Artin K; Kershaw NJ; Tan CW; Witchard HM; Ebert G; Charman SA; Street I; Kavallaris M; Haber M; Fletcher JI; Asselin-Labat ML; Scott CL; Visvader JE; Lindeman GJ; Watson KG; Burgess AW; Lessene G, 2021, 'Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors', Cell Death and Disease, vol. 12, http://dx.doi.org/10.1038/s41419-020-03269-0
    Journal articles | 2021
    Professor Michelle Haber
    Khan A; Gamble L; Upton D; Yu D; Pandher R; Mayoh C; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', NEURO-ONCOLOGY, vol. 23, pp. 40 - 41, http://dx.doi.org/10.1093/neuonc/noab090.163
    Journal articles | 2021
    Professor Michelle Haber
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2021, 'Cell-based methods for the identification of Myc-inhibitory small molecules', Methods Mol Biol, vol. 2318, pp. 337 - 346, http://dx.doi.org/10.1007/978-1-0716-1476-1_19
    Journal articles | 2021
    Professor Michelle Haber
    Xu N; Tse B; Yang L; Tang TC; Haber M; Micklethwaite K; Dolnikov A, 2021, 'Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy', IMMUNOTARGETS AND THERAPY, vol. 10, pp. 123 - 140, http://dx.doi.org/10.2147/ITT.S296161
    Journal articles | 2020
    Professor Michelle Haber
    Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, vol. 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014
    Journal articles | 2020
    Professor Michelle Haber
    Voli F; Valli E; Lerra L; Kimpton K; Saletta F; Giorgi FM; Mercatelli D; Rouaen JRC; Shen S; Murray JE; Ahmed-Cox A; Cirillo G; Mayoh C; Beavis PA; Haber M; Trapani JA; Kavallaris M; Vittorio O, 2020, 'Intratumoral copper modulates PD-L1 expression and influences tumor immune evasion', Cancer Research, vol. 80, pp. 4129 - 4144, http://dx.doi.org/10.1158/0008-5472.CAN-20-0471
    Journal articles | 2020
    Professor Michelle Haber
    Korotchkina L; Kazyulkin D; Komarov PG; Polinsky A; Andrianova EL; Joshi S; Gupta M; Vujcic S; Kononov E; Toshkov I; Tian Y; Krasnov P; Chernov MV; Veith J; Antoch MP; Middlemiss S; Somers K; Lock RB; Norris MD; Henderson MJ; Haber M; Chernova OB; Gudkov AV, 2020, 'OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis', Leukemia, vol. 34, pp. 1828 - 1839, http://dx.doi.org/10.1038/s41375-019-0692-5
    Journal articles | 2020
    Professor Michelle Haber
    Somers K; Evans K; Cheung L; Karsa M; Pritchard T; Kosciolek A; Bongers A; El-Ayoubi A; Forgham H; Middlemiss S; Mayoh C; Jones L; Gupta M; Kees UR; Chernova O; Korotchkina L; Gudkov AV; Erickson SW; Teicher B; Smith MA; Norris MD; Haber M; Lock RB; Henderson MJ, 2020, 'Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia', Leukemia, vol. 34, pp. 1524 - 1539, http://dx.doi.org/10.1038/s41375-019-0683-6
    Journal articles | 2020
    Professor Michelle Haber
    Xie J; Span M; van Maarseveen E; Langenhorst J; Boddy AV; Sia KCS; Sutton R; Venn N; Punt AM; Tyrrell V; Haber M; Trahair T; Lau L; Marshall GM; Lock RB, 2020, 'Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia', Pediatric Blood and Cancer, vol. 67, pp. e28133, http://dx.doi.org/10.1002/pbc.28133
    Journal articles | 2020
    Professor Michelle Haber
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Professor Michelle Haber
    Huynh T; Murray J; Flemming CL; Kamili A; Hofmann U; Cheung L; Roundhill EA; Yu DMT; Webber HT; Schwab M; Henderson MJ; Haber M; Norris MD; Fletcher JI, 2020, 'CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth', Biochemical Pharmacology, vol. 172, http://dx.doi.org/10.1016/j.bcp.2019.113770
    Journal articles | 2020
    Professor Michelle Haber
    Khan A; Valli E; Lam H; Scott DA; Murray J; Hanssen KM; Eden G; Gamble LD; Pandher R; Flemming CL; Allan S; Osterman AL; Haber M; Norris MD; Fletcher JI; Yu DMT, 2020, 'Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition', Oncogene, vol. 39, pp. 3555 - 3570, http://dx.doi.org/10.1038/s41388-020-1235-2
    Journal articles | 2020
    Professor Michelle Haber
    Hawkins C; Pfister S; Jones DTW; Shah NN; Gilbertson RJ; Sweet-Cordero EA; Dyer MA; Mossé YP; Haber M; DuBois SG, 2020, 'Advances and Challenges in Pediatric and Childhood Cancers', Cancer Cell, vol. 38, pp. 429 - 432, http://dx.doi.org/10.1016/j.ccell.2020.09.013
    Journal articles | 2020
    Professor Michelle Haber
    Jung M; Gao J; Cheung L; Bongers A; Somers K; Clifton M; Ramsay EE; Russell AJ; Valli E; Gifford AJ; George J; Kennedy CJ; Wakefield MJ; Topp M; Ho GY; Scott CL; Bowtell DD; deFazio A; Norris MD; Haber M; Henderson MJ, 2020, 'ABCC4/MRP4 contributes to the aggressiveness of Myc-associated epithelial ovarian cancer', International Journal of Cancer, vol. 147, pp. 2225 - 2238, http://dx.doi.org/10.1002/ijc.33005
    Journal articles | 2020
    Professor Michelle Haber
    Gao J; Jung MS; Mayoh C; Venkat P; Hannan KM; Fletcher JI; Kamili A; Gifford AJ; Kusnadi EP; Pearson RB; Hannan RD; Haber M; Norris MD; Somers K; Henderson MJ, 2020, 'Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression', Cancer Research, vol. 80, pp. 3706 - 3718, http://dx.doi.org/10.1158/0008-5472.CAN-19-3914
    Journal articles | 2020
    Professor Michelle Haber
    Sia KCS; Zhong L; Mayoh C; Norris MD; Haber M; Marshall GM; Raftery MJ; Lock RB, 2020, 'Targeting TSLP-induced tyrosine kinase signaling pathways in CRLF2-Rearranged Ph-like ALL', Molecular Cancer Research, vol. 18, pp. 1767 - 1776, http://dx.doi.org/10.1158/1541-7786.MCR-19-1098
    Journal articles | 2020
    Professor Michelle Haber
    Khuong-Quang DA; Brown LM; Wong M; Mayoh C; Sexton-Oates A; Kumar A; Pinese M; Nagabushan S; Lau L; Ludlow LE; Gifford AJ; Rodriguez M; Desai J; Fox SB; Haber M; Ziegler DS; Hansford JR; Marshall GM; Cowley MJ; Ekert PG, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, vol. 6, http://dx.doi.org/10.1101/MCS.A005710
    Journal articles | 2020
    Professor Michelle Haber
    Terry RL; Meyran D; Ziegler DS; Haber M; Ekert PG; Trapani JA; Neeson PJ, 2020, 'Immune profiling of pediatric solid tumors', Journal of Clinical Investigation, vol. 130, pp. 3391 - 3402, http://dx.doi.org/10.1172/JCI137181
    Journal articles | 2020
    Professor Michelle Haber
    Kamili A; Gifford AJ; Li N; Mayoh C; Chow S-O; Failes TW; Eden GL; Cadiz R; Xie J; Lukeis RE; Norris MD; Haber M; McCowage GB; Arndt GM; Trahair TN; Fletcher JI, 2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer, http://dx.doi.org/10.1038/s41416-019-0682-4
    Journal articles | 2020
    Professor Michelle Haber
    Ferrucci F; Ciaccio R; Monticelli S; Pigini P; Di Giacomo S; Purgato S; Erriquez D; Bernardoni R; Norris MD; Haber M; Milazzo G; Perini G, 2020, 'Corrigendum to: “MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma” [Biochim. Biophys. Acta, Gene Regul. Mech. 1861 (2018) 235–245] (BBA - Gene Regulatory Mechanisms (2018) 1861(3) (235–245), (S1874939917302894), (10.1016/j.bbagrm.2018.01.007))', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1863, http://dx.doi.org/10.1016/j.bbagrm.2020.194645
    Journal articles | 2019
    Professor Michelle Haber
    Dorstyn L; Hackett-Jones E; Nikolic A; Norris MD; Lim Y; Toubia J; Haber M; Kumar S, 2019, 'Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling', Cell Death and Disease, vol. 10, http://dx.doi.org/10.1038/s41419-018-1296-0
    Journal articles | 2019
    Professor Michelle Haber
    Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, vol. 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
    Journal articles | 2019
    Professor Michelle Haber
    Liu PY; Tee AE; Milazzo G; Hannan KM; Maag J; Mondal S; Atmadibrata B; Bartonicek N; Peng H; Ho N; Mayoh C; Ciaccio R; Sun Y; Henderson MJ; Gao J; Everaert C; Hulme AJ; Wong M; Lan Q; Cheung BB; Shi L; Wang JY; Simon T; Fischer M; Zhang XD; Marshall GM; Norris MD; Haber M; Vandesompele J; Li J; Mestdagh P; Hannan RD; Dinger ME; Perini G; Liu T, 2019, 'The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35', Nature Communications, vol. 10, pp. 5026, http://dx.doi.org/10.1038/s41467-019-12971-3
    Journal articles | 2019
    Professor Michelle Haber
    Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410, http://dx.doi.org/10.1038/s41375-018-0354-z
    Journal articles | 2019
    Professor Michelle Haber
    Somers K; Kosciolek A; Bongers A; El-Ayoubi A; Karsa M; Mayoh C; Wadham C; Middlemiss S; Neznanov N; Kees UR; Lock RB; Gudkov A; Sutton R; Gurova K; Haber M; Norris MD; Henderson MJ, 2019, 'Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia', International Journal of Cancer, http://dx.doi.org/10.1002/ijc.32582
    Journal articles | 2019
    Professor Michelle Haber
    Koach J; Holien JK; Massudi H; Carter DR; Ciampa OC; Herath M; Lim T; Seneviratne JA; Milazzo G; Murray JE; McCarroll JA; Liu B; Mayoh C; Keenan B; Stevenson BW; Gorman MA; Bell JL; Doughty L; Hüttelmaier S; Oberthuer A; Fischer M; Gifford AJ; Liu T; Zhang X; Zhu S; Gustafson WC; Haber M; Norris MD; Fletcher JI; Perini G; Parker MW; Cheung BB; Marshall GM, 2019, 'Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface', Cancer Research, vol. 79, pp. 5652 - 5667, http://dx.doi.org/10.1158/0008-5472.CAN-19-1112
    Journal articles | 2019
    Professor Michelle Haber
    Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, vol. 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
    Journal articles | 2019
    Professor Michelle Haber
    Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, vol. 10, pp. 3319, http://dx.doi.org/10.1038/s41467-019-11132-w
    Journal articles | 2019
    Professor Michelle Haber
    Gana CC; Hanssen KM; Yu DMT; Flemming CL; Wheatley MS; Conseil G; Cole SPC; Norris MD; Haber M; Fletcher JI, 2019, 'MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells', Biochemical Pharmacology, vol. 168, pp. 237 - 248, http://dx.doi.org/10.1016/j.bcp.2019.07.009
    Journal articles | 2019
    Professor Michelle Haber
    Jones DTW; Banito A; Grünewald TGP; Haber M; Jäger N; Kool M; Milde T; Molenaar JJ; Nabbi A; Pugh TJ; Schleiermacher G; Smith MA; Westermann F; Pfister SM, 2019, 'Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours', Nature Reviews Cancer, vol. 19, pp. 420 - 438, http://dx.doi.org/10.1038/s41568-019-0169-x
    Journal articles | 2019
    Professor Michelle Haber
    Rokita JL; Rathi KS; Cardenas MF; Upton KA; Jayaseelan J; Cross KL; Pfeil J; Egolf LE; Way GP; Farrel A; Kendsersky NM; Patel K; Gaonkar KS; Modi A; Berko ER; Lopez G; Vaksman Z; Mayoh C; Nance J; McCoy K; Haber M; Evans K; McCalmont H; Bendak K; Böhm JW; Marshall GM; Tyrrell V; Kalletla K; Braun FK; Qi L; Du Y; Zhang H; Lindsay HB; Zhao S; Shu J; Baxter P; Morton C; Kurmashev D; Zheng S; Chen Y; Bowen J; Bryan AC; Leraas KM; Coppens SE; Doddapaneni HV; Momin Z; Zhang W; Sacks GI; Hart LS; Krytska K; Mosse YP; Gatto GJ; Sanchez Y; Greene CS; Diskin SJ; Vaske OM; Haussler D; Gastier-Foster JM; Kolb EA; Gorlick R; Li XN; Reynolds CP; Kurmasheva RT; Houghton PJ; Smith MA; Lock RB; Raman P; Wheeler DA; Maris JM, 2019, 'Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design', Cell Reports, vol. 29, pp. 1675 - 1689.e9, http://dx.doi.org/10.1016/j.celrep.2019.09.071
    Journal articles | 2019
    Professor Michelle Haber
    Gonzales-Aloy E; Connerty P; Salik B; Liu B; Woo AJ; Haber M; Norris MD; Wang J; Wang JY, 2019, 'MiR-101 suppresses the development of MLL-rearranged acute myeloid leukemia', Haematologica, vol. 104, pp. e296 - e299, http://dx.doi.org/10.3324/haematol.2018.209437
    Journal articles | 2019
    Professor Michelle Haber
    Fultang L; Gamble LD; Gneo L; Berry AM; Egan SA; De Bie F; Yogev O; Eden GL; Booth S; Brownhill S; Vardon A; McConville CM; Cheng PN; Norris MD; Etchevers HC; Murray J; Ziegler DS; Chesler L; Schmidt R; Burchill SA; Haber M; De Santo C; Mussai F, 2019, 'Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma', Cancer Research, vol. 79, pp. 611 - 624, http://dx.doi.org/10.1158/0008-5472.CAN-18-2139
    Journal articles | 2018
    Professor Michelle Haber
    Ooi CY; Carter DR; Liu B; Mayoh C; Beckers A; Lalwani A; Nagy Z; De Brouwer S; Decaesteker B; Hung TT; Norris MD; Haber M; Liu T; De Preter K; Speleman F; Cheung BB; Marshall GM, 2018, 'Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN', Cancer Research, vol. 78, pp. 3122 - 3134, http://dx.doi.org/10.1158/0008-5472.CAN-17-3034
    Journal articles | 2018
    Professor Michelle Haber
    Ferrucci F; Ciaccio R; Monticelli S; Pigini P; di Giacomo S; Purgato S; Erriquez D; Bernardoni R; Norris M; Haber M; Milazzo G; Perini G, 2018, 'MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1861, pp. 235 - 245, http://dx.doi.org/10.1016/j.bbagrm.2018.01.007
    Journal articles | 2018
    Professor Michelle Haber
    Jung M; Russell A; Kennedy C; Gifford A, 2018, 'Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer', JNCI: Cancer Spectrum, vol. 2, http://dx.doi.org/10.1093/jncics/pky047
    Journal articles | 2018
    Professor Michelle Haber
    Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, vol. 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
    Journal articles | 2018
    Professor Michelle Haber
    Sutton R; Venn NC; Law T; Boer JM; Trahair TN; Ng A; Den Boer ML; Dissanayake A; Giles JE; Dalzell P; Mayoh C; Barbaric D; Revesz T; Alvaro F; Pieters R; Haber M; Norris MD; Schrappe M; Dalla Pozza L; Marshall GM, 2018, 'A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children', British Journal of Haematology, vol. 180, pp. 550 - 562, http://dx.doi.org/10.1111/bjh.15056
    Journal articles | 2018
    Professor Michelle Haber
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, vol. 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
    Journal articles | 2018
    Professor Michelle Haber
    Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M, 2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, vol. 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
    Journal articles | 2018
    Professor Michelle Haber
    Marachelian A; Hogarty MD; Flynn A; Liu K; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer C; Norris M; Haber M; Groshen SG; Ziegler DS; Matthay KK, 2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', Journal of Clinical Oncology, vol. 36, pp. 10558 - 10558, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.10558
    Journal articles | 2018
    Professor Michelle Haber
    Somers K; Evans K; Cheung L; Korotchkina L; Chernova O; Gudkov A; Norris M; Haber M; Lock R; Henderson M, 2018, 'PO-028 Effective targeting of NAD+biosynthesis in patient-derived xenograft models of high-risk paediatric acute lymphoblastic leukaemia', ESMO Open, vol. 3, pp. A238 - A238, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.563
    Journal articles | 2017
    Professor Michelle Haber
    Burchill SA; Beiske K; Shimada H; Ambros PF; Seeger R; Tytgat GAM; Brock PR; Haber M; Park JR; Berthold F, 2017, 'Recommendations for the standardization of bone marrow disease assessment and reporting in children with neuroblastoma on behalf of the International Neuroblastoma Response Criteria Bone Marrow Working Group', Cancer, vol. 123, pp. 1095 - 1105, http://dx.doi.org/10.1002/cncr.30380
    Journal articles | 2017
    Professor Michelle Haber
    Dagg RA; Pickett HA; Neumann AA; Napier CE; Henson JD; Teber ET; Arthur JW; Reynolds CP; Murray J; Haber M; Sobinoff AP; Lau LMS; Reddel RR, 2017, 'Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres', Cell Reports, vol. 19, pp. 2544 - 2556, http://dx.doi.org/10.1016/j.celrep.2017.05.087
    Journal articles | 2017
    Professor Michelle Haber
    Jung MS; Russell AJ; Liu B; George J; Liu PY; Liu T; DeFazio A; Bowtell DDL; Oberthuer A; London WB; Fletcher JI; Haber M; Norris MD; Henderson MJ, 2017, 'A Myc activity signature predicts poor clinical outcomes in Myc-associated cancers', Cancer Research, vol. 77, pp. 971 - 981, http://dx.doi.org/10.1158/0008-5472.CAN-15-2906
    Journal articles | 2017
    Professor Michelle Haber
    Murray J; Valli E; Yu DMT; Truong AM; Gifford AJ; Eden GL; Gamble LD; Hanssen KM; Flemming CL; Tan A; Tivnan A; Allan S; Saletta F; Cheung L; Ruhle M; Schuetz JD; Henderson MJ; Byrne JA; Norris MD; Haber M; Fletcher JI, 2017, 'Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo', European Journal of Cancer, vol. 83, pp. 132 - 141, http://dx.doi.org/10.1016/j.ejca.2017.06.024
    Journal articles | 2016
    Professor Michelle Haber
    Xue C; Yu DMT; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Valli E; Russell AJ; London WB; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4', Oncotarget, vol. 7, pp. 54937 - 54951, http://dx.doi.org/10.18632/oncotarget.10709
    Journal articles | 2016
    Professor Michelle Haber
    Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, vol. 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539
    Journal articles | 2016
    Professor Michelle Haber
    Lynch JR; Yi H; Casolari DA; Voli F; Gonzales-Aloy E; Fung TK; Liu B; Brown A; Liu T; Haber M; Norris MD; Lewis ID; So CWE; D'Andrea RJ; Wang JY, 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, vol. 30, pp. 1745 - 1748, http://dx.doi.org/10.1038/leu.2016.24
    Journal articles | 2016
    Professor Michelle Haber
    Decock A; Ongenaert M; Cannoodt R; Verniers K; Wilde BD; Laureys G; Van Roy N; Berbegall AP; Bienertova-Vasku J; Bown N; Clément N; Combaret V; Haber M; Hoyoux C; Murray J; Noguera R; Pierron G; Schleiermacher G; Schulte JH; Stallings RL; Tweddle DA; De Preter K; Speleman F; Vandesompele J, 2016, 'Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma', Oncotarget, vol. 7, pp. 1960 - 1972, http://dx.doi.org/10.18632/oncotarget.6477
    Journal articles | 2016
    Professor Michelle Haber
    Tee AE; Liu B; Song R; Li J; Pasquier E; Cheung BB; Jiang C; Marshall GM; Haber M; Norris MD; Fletcher JI; Dinger ME; Liu T, 2016, 'The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression', Oncotarget, vol. 7, pp. 8663 - 8675, http://dx.doi.org/10.18632/oncotarget.6675
    Journal articles | 2016
    Professor Michelle Haber
    Fletcher JI; Williams RT; Henderson MJ; Norris MD; Haber M, 2016, 'ABC transporters as mediators of drug resistance and contributors to cancer cell biology', Drug Resistance Updates, vol. 26, pp. 1 - 9, http://dx.doi.org/10.1016/j.drup.2016.03.001
    Journal articles | 2016
    Professor Michelle Haber
    French JD; Johnatty SE; Lu Y; Beesley J; Gao B; Kalimutho M; Henderson MJ; Russell AJ; Kar S; Chen X; Hillman KM; Kaufmann S; Sivakumaran H; O'Reilly M; Wang C; Korbie DJ; Lambrechts D; Despierre E; Van Nieuwenhuysen E; Lambrechts S; Vergote I; Karlan B; Lester J; Orsulic S; Walsh C; Fasching PA; Beckmann MW; Ekici AB; Hein A; Matsuo K; Hosono S; Pisterer J; Hillemanns P; Nakanishi T; Yatabe Y; Goodman MT; Lurie G; Matsuno RK; Thompson PJ; Pejovic T; Bean Y; Heitz F; Harter P; Du Bois A; Schwaab I; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Lundvall L; Engelholm SA; Brown B; Flanagan JM; Metcalf MD; Siddiqui N; Sellers T; Fridley B; Cunningham J; Schildkraut JM; Iversen E; Weber RP; Brennan D; Berchuck A; Pharoah P; Harnett P; Norris MD; Haber M; Goode EL; Lee JS; Khanna KK; Meyer KB; Chenevix-Trench G; DeFazio A; Edwards SL; MacGregor S, 2016, 'Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer', Oncotarget, vol. 7, pp. 6353 - 6368, http://dx.doi.org/10.18632/oncotarget.7047
    Journal articles | 2016
    Professor Michelle Haber
    Somers K; Chudakova DA; Middlemiss SMC; Wen VW; Clifton M; Kwek A; Liu B; Mayoh C; Bongers A; Karsa M; Pan S; Cruikshank S; Scandlyn M; Hoang W; Imamura T; Kees UR; Gudkov AV; Chernova OB; Haber M; Norris MD; Henderson MJ, 2016, 'CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements', Oncotarget, vol. 7, pp. 46067 - 46087, http://dx.doi.org/10.18632/oncotarget.10022
    Journal articles | 2016
    Professor Michelle Haber
    Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, vol. 374, pp. 315 - 323, http://dx.doi.org/10.1016/j.canlet.2016.02.021
    Journal articles | 2016
    Professor Michelle Haber
    Carter DR; Sutton SK; Pajic M; Murray J; Sekyere EO; Fletcher J; Beckers A; De Preter K; Speleman F; George RE; Haber M; Norris MD; Cheung BB; Marshall GM, 2016, 'Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis', Molecular Oncology, vol. 10, pp. 866 - 878, http://dx.doi.org/10.1016/j.molonc.2016.02.004
    Journal articles | 2016
    Professor Michelle Haber
    Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640
    Journal articles | 2016
    Professor Michelle Haber
    Koach J; Murray JE; McCarroll J; Milazzo G; Perini G; Haber M; Norris MD; Fletcher JI; Cheung BB; Marshall GM, 2016, 'Proffered Paper: Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', European Journal of Cancer, vol. 61, pp. S7 - S7, http://dx.doi.org/10.1016/s0959-8049(16)61016-x
    Journal articles | 2016
    Professor Michelle Haber
    Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, vol. 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201
    Journal articles | 2016
    Professor Michelle Haber
    O'Brien R; Tran SL; Maritz MF; Liu B; Kong CF; Purgato S; Yang C; Murray J; Russell AJ; Flemming CL; von Jonquieres G; Pickett HA; London WB; Haber M; Gunaratne PH; Norris MD; Perini G; Fletcher JI; MacKenzie KL, 2016, 'MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin', Cancer Research, vol. 76, pp. 3604 - 3617, http://dx.doi.org/10.1158/0008-5472.CAN-15-0879
    Journal articles | 2015
    Professor Michelle Haber
    Bassiri H; Benavides A; Haber M; Gilmour SK; Norris MD; Hogarty MD, 2015, 'Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma', TRANSLATIONAL PEDIATRICS, vol. 4, pp. 226 - 238, http://dx.doi.org/10.3978/j.issn.2224-4336.2015.04.06
    Journal articles | 2015
    Professor Michelle Haber
    Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, vol. 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005
    Journal articles | 2015
    Professor Michelle Haber
    Milne E; Greenop KR; Scott RJ; Haber M; Norris MD; Attia J; Jamieson SE; Miller M; Bower C; Bailey HD; Dawson S; McCowage GB; De Klerk NH; Van Bockxmeer FM; Armstrong BK, 2015, 'Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia', Cancer Epidemiology Biomarkers and Prevention, vol. 24, pp. 48 - 56, http://dx.doi.org/10.1158/1055-9965.EPI-14-0680
    Journal articles | 2015
    Professor Michelle Haber
    Yu DMT; Huynh T; Truong AM; Haber M; Norris MD, 2015, 'ABC Transporters and Neuroblastoma', Advances in Cancer Research, vol. 125, pp. 139 - 170, http://dx.doi.org/10.1016/bs.acr.2014.10.005
    Journal articles | 2015
    Professor Michelle Haber
    Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.aab1803
    Journal articles | 2015
    Professor Michelle Haber
    Sutton R; Shaw PJ; Venn NC; Law T; Dissanayake A; Kilo T; Haber M; Norris MD; Fraser C; Alvaro F; Revesz T; Trahair TN; Dalla-Pozza L; Marshall GM; O'Brien TA, 2015, 'Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia', British Journal of Haematology, vol. 168, pp. 395 - 404, http://dx.doi.org/10.1111/bjh.13142
    Journal articles | 2015
    Professor Michelle Haber
    Lau DT; Flemming CL; Gherardi S; Perini G; Oberthuer A; Fischer M; Juraeva D; Brors B; Xue C; Norris MD; Marshall GM; Haber M; Fletcher JI; Ashton LJ, 2015, 'MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma', Oncotarget, vol. 6, pp. 15510 - 15523, http://dx.doi.org/10.18632/oncotarget.3732
    Journal articles | 2015
    Professor Michelle Haber
    Greenop KR; Scott RJ; Attia J; Bower C; De Klerk NH; Norris MD; Haber M; Jamieson SE; Van Bockxmeer FM; Gottardo NG; Ashton LJ; Armstrong BK; Milne E, 2015, 'Folate pathway gene polymorphisms and risk of childhood brain tumors: Results from an Australian case-control study', Cancer Epidemiology Biomarkers and Prevention, vol. 24, pp. 931 - 937, http://dx.doi.org/10.1158/1055-9965.EPI-14-1248
    Journal articles | 2014
    Professor Michelle Haber
    Dietrich PA; Yang C; Leung HHL; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY, 2014, 'GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis', Blood, vol. 124, pp. 3284 - 3294, http://dx.doi.org/10.1182/blood-2013-10-532523
    Journal articles | 2014
    Professor Michelle Haber
    Dorstyn L; Puccini J; Nikolic A; Shalini S; Wilson CH; Norris MD; Haber M; Kumar S, 2014, 'An unexpected role for caspase-2 in neuroblastoma', Cell Death and Disease, vol. 5, http://dx.doi.org/10.1038/cddis.2014.342
    Journal articles | 2014
    Professor Michelle Haber
    Shahbazi J; Scarlett CJ; Norris MD; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock RB; Liu T, 2014, 'Histone Deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Oncotarget, vol. 5, pp. 4257 - 4268, http://dx.doi.org/10.18632/oncotarget.1991
    Journal articles | 2014
    Professor Michelle Haber
    Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, vol. 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003
    Journal articles | 2014
    Professor Michelle Haber
    Tee EL; Ling D; Nelson C; Atmadibrata B; Dinger M; XU N; Mizukami T; Liu PY; Liu B; Cheung B; Pasquier E; Haber M; Norris MD; Suzuki T; Marshall GM; Liu T, 2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1', Oncotarget, vol. 5, pp. 1793 - 1804, http://dx.doi.org/10.18632/oncotarget.1785
    Journal articles | 2014
    Professor Michelle Haber
    Hedditch EL; Gao B; Russell AJ; Lu Y; Emmanuel C; Beesley J; Johnatty SE; Chen X; Harnett P; George J; Williams RT; Flemming C; Lambrechts D; Despierre E; Lambrechts S; Vergote I; Karlan B; Lester J; Orsulic S; Walsh C; Fasching P; Beckmann MW; Ekici AB; Hein A; Matsuo K; Hosono S; Nakanishi T; Yatabe Y; Pejovic T; Bean Y; Heitz F; Harter P; Du Bois A; Schwaab I; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Lundvall L; Engelholm SA; Brown B; Flanagan J; Metcalf MD; Siddiqui N; Sellers T; Fridley B; Cunningham J; Schildkraut J; Iversen E; Weber RP; Berchuck A; Goode E; Bowtell DD; Chenevix-Trench G; Defazio A; Norris MD; Macgregor S; Haber M; Henderson MJ, 2014, 'ABCA transporter gene expression and poor outcome in epithelial ovarian cancer', Journal of the National Cancer Institute, vol. 106, http://dx.doi.org/10.1093/jnci/dju149
    Journal articles | 2014
    Professor Michelle Haber
    Gao B; Russell A; Beesley J; Chen XQ; Healey S; Henderson M; Wong M; Emmanuel C; Galletta L; Johnatty SE; Bowtell D; Haber M; Norris M; Harnett P; Chenevix-Trench G; Balleine RL; Defazio A; Gertig D; Green A; Webb P; Hung J; Moore S; Traficante N; Fereday S; Harrap K; Sadkowsky T; Pandeya N; Stuart-Harris R; Kirsten F; Rutovitz J; Clingan P; Glasgow A; Proietto A; Braye S; Otton G; Shannon J; Bonaventura T; Stewart J; Begbie S; Friedlander M; Bell D; Baron-Hay S; Ferrier A; Gard G; Nevell D; Pavlakis N; Valmadre S; Young B; Camaris C; Crouch R; Edwards L; Hacker N; Marsden D; Robertson G; Beale P; Beith J; Carter J; Dalrymple C; Hamilton A; Houghton R; Russell P; Links M; Grygiel J; Hill J; Brand A; Byth K; Jaworski R; Sharma R; Achen A; Wain G; Ward B; Papadimos D; Crandon A; Cummings M; Horwood K; Obermair A; Perrin L; Wyld D; Nicklin J; Davy M; Oehler MK; Hall C; Dodd T; Healy T; Pittman K; Henderson D; Miller J; Pierdes J; Blomfield P; Challis D; McIntosh R; Parker A; Brown B; Rome R; Allen D; Grant P; Hyde S; Laurie R; Robbie M; Healy D, 2014, 'Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer', Scientific Reports, vol. 4, http://dx.doi.org/10.1038/srep04669
    Journal articles | 2014
    Professor Michelle Haber
    Cheung L; Flemming CL; Watt F; Masada N; Yu DMT; Huynh T; Conseil G; Tivnan A; Polinsky A; Gudkov AV; Munoz MA; Vishvanath A; Cooper DMF; Henderson MJ; Cole SPC; Fletcher JI; Haber M; Norris MD, 2014, 'High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)', Biochemical Pharmacology, vol. 91, pp. 97 - 108, http://dx.doi.org/10.1016/j.bcp.2014.05.023
    Journal articles | 2014
    Professor Michelle Haber
    Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, vol. 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032
    Journal articles | 2014
    Professor Michelle Haber
    Heong V; Topp M; Rutkowski R; Ananda S; Wong S; Swisher E; Lindeman G; Haber M; Norris MD; Haluska P; Wakefield M; Bowtell D; Scott CL; Lindeman G, 2014, 'OP0024 Use of novel patient-derived xenografts and molecular subtyping to improve precision medicine in high-grade serous ovarian cancer', European Journal of Cancer, vol. 50, pp. e9 - e9, http://dx.doi.org/10.1016/j.ejca.2014.03.042
    Journal articles | 2014
    Professor Michelle Haber
    Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, vol. 50, pp. 135 - 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7
    Journal articles | 2013
    Professor Michelle Haber
    Liu PY; Xu N; Malyukova A; Scarlett CJ; Sun YT; Zhang XD; Ling D; Su SP; Nelson CA; Chang DK; Koach J; Tee AE; Haber M; Norris MD; Rooman I; Toon C; Xue C; Cheung B; Kumar S; Marshall GM; Biankin AV; Liu T, 2013, 'The histone deacetylase SIRT2 stabilizes Myc oncoproteins', Cell Death and Differentiation, vol. 20, pp. 503 - 514, http://dx.doi.org/10.1038/cdd.2012.147
    Journal articles | 2013
    Professor Michelle Haber
    Kim PY; Rahmanto AS; Tan O; Norris MD; Haber M; Marshall GM; Cheung BB, 2013, 'TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells', Apoptosis, vol. 18, pp. 639 - 651, http://dx.doi.org/10.1007/s10495-013-0813-y
    Journal articles | 2013
    Professor Michelle Haber
    Johnatty SE; Beesley J; Gao B; Chen X; Lu Y; Law MH; Henderson MJ; Russell AJ; Hedditch EL; Emmanuel C; Fereday S; Webb PM; Goode EL; Vierkant RA; Fridley BL; Cunningham JM; Fasching PA; Beckmann MW; Ekici AB; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Brown R; Paul J; Lambrechts S; Despierre E; Vergote I; Lester J; Karlan BY; Heitz F; Du Bois A; Harter P; Schwaab I; Bean Y; Pejovic T; Levine DA; Goodman MT; Camey ME; Thompson PJ; Lurie G; Shildkraut J; Berchuck A; Terry KL; Cramer DW; Norris MD; Haber M; MacGregor S; DeFazio A; Chenevix-Trench G, 2013, 'ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and the Cancer Genome Atlas', Gynecologic Oncology, vol. 131, pp. 8 - 14, http://dx.doi.org/10.1016/j.ygyno.2013.07.107
    Journal articles | 2013
    Professor Michelle Haber
    Sekyere E; Thomas WD; Keating J; Calao M; Cui HJ; Chen JB; Raif A; Jankowski K; Cheung B; Davies NP NP; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation', Oncogene, vol. 32, pp. 3616 - 3626, http://dx.doi.org/10.1038/onc.2012.368
    Journal articles | 2013
    Professor Michelle Haber
    Marshall GM; Dalla Pozza L; Sutton R; Ng A; De Groot-Kruseman HA; Van Der Velden VH; Venn NC; Van Den Berg H; De Bont ESJM; Maarten Egeler R; Hoogerbrugge PM; Kaspers GJL; Bierings MB; Van Der Schoot E; Van Dongen J; Law T; Cross S; Mueller H; De Haas V; Haber M; Révész T; Alvaro F; Suppiah R; Norris MD; Pieters R, 2013, 'High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation', Leukemia, vol. 27, pp. 1497 - 1503, http://dx.doi.org/10.1038/leu.2013.44
    Journal articles | 2013
    Professor Michelle Haber
    Karsa M; Dalla Pozza L; Venn NC; Law T; Shi R; Giles JE; Bahar AY; Cross S; Catchpoole D; Haber M; Marshall GM; Norris MD; Sutton R, 2013, 'Improving the Identification of High Risk Precursor B Acute Lymphoblastic Leukemia Patients with Earlier Quantification of Minimal Residual Disease', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0076455
    Journal articles | 2013
    Professor Michelle Haber
    Malyukova A; Papa R; O'Brien R; Giles JE; Trahair TN; Pozza LD; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Marshall GM; Giles J, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, vol. 27, pp. 1053 - 1062, http://dx.doi.org/10.1038/leu.2012.361
    Journal articles | 2013
    Professor Michelle Haber
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2013, 'Cell-based methods for the identification of Myc-inhibitory small molecules', Methods in Molecular Biology, vol. 1012, pp. 255 - 264, http://dx.doi.org/10.1007/978-1-62703-429-6_18
    Journal articles | 2012
    Professor Michelle Haber
    Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, vol. 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162
    Journal articles | 2012
    Professor Michelle Haber
    Cheung BB; Koach J; Tan O; Kim P; Bell J; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris MD; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott J; Cooper C; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro', Journal of Pathology, vol. 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986
    Journal articles | 2012
    Professor Michelle Haber
    Schleiermacher G; Mosseri V; London WB; Maris JM; Brodeur GM; Attiyeh E; Haber M; Khan J; Nakagawara A; Speleman F; Noguera R; Tonini GP; Fischer M; Ambros I; Monclair T; Matthay KK; Ambros P; Cohn SL; Pearson ADJ, 2012, 'Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project', British Journal of Cancer, vol. 107, pp. 1418 - 1422, http://dx.doi.org/10.1038/bjc.2012.375
    Journal articles | 2012
    Professor Michelle Haber
    Huynh T; Norris MD; Haber M; Henderson MJ, 2012, 'ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma', FRONTIERS IN ONCOLOGY, vol. 2, http://dx.doi.org/10.3389/fonc.2012.00178
    Journal articles | 2012
    Professor Michelle Haber
    Venn NC; Van der velden VHJ; De bie M; Waanders E; Giles JE; Law T; Kuiper RP; de Haas V; Mullighan CG; Haber M; Marshall GM; Norris MD; Van dongen JJM; Sutton R; Giles J; Law T, 2012, 'Highly sensitive MRD tests for ALL based on the IKZF1 Delta 3-6 microdeletion', Leukemia, vol. 26, pp. 1414 - 1416, http://dx.doi.org/10.1038/leu.2011.348
    Journal articles | 2012
    Professor Michelle Haber
    Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, vol. 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352
    Journal articles | 2012
    Professor Michelle Haber
    Lau DT; Hesson L; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma', Clinical Cancer Research, vol. 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294
    Journal articles | 2012
    Professor Michelle Haber
    Fletcher JI; Gherardi S; Murray J; Burkhart C; Russell A; Valli E; Smith J; Oberthuer A; Ashton LJ; London WB; Marshall GM; Norris MD; Perini G; Haber M, 2012, 'N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma', Cancer Research, vol. 72, pp. 845 - 853, http://dx.doi.org/10.1158/0008-5472.CAN-11-1885
    Journal articles | 2012
    Professor Michelle Haber
    Wang JY; Sprod O; Haber M; Norris MD, 2012, 'Epigenetic Elimination of Mixed-Lineage Leukemia Leukemic Stem Cells by a Potent Small Molecule PRC2 Inhibitor.', Blood, vol. 120, pp. 2456 - 2456, http://dx.doi.org/10.1182/blood.v120.21.2456.2456
    Journal articles | 2012
    Professor Michelle Haber
    Chenevix-Trench G; Lu Y; Johnatty S; Gamazon E; Beesley J; Chen X; Gao B; Harnett P; Stephanie Huang R; Despierre E; Heitz F; Hogdall E; Hogdall C; Brown R; Moyisch K; Fasching P; Goode E; Russell A; Henderson M; Haber M; Dolan E; Macgregor S; deFazio A, 2012, 'Identification of a genetic variant associated with treatment outcome in ovarian cancer: the potential role of cholesterol metabolism as a determinant of response to chemotherapy', Hereditary Cancer in Clinical Practice, vol. 10, pp. A36 - A36, http://dx.doi.org/10.1186/1897-4287-10-s2-a36
    Journal articles | 2012
    Professor Michelle Haber
    Lau DT; Hesson LB; Norris MD; Haber M; Marshall GM; Ashton LJ, 2012, 'Prognostic significance of promoter DNA methylation in patients with neuroblastoma', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1425
    Journal articles | 2012
    Professor Michelle Haber
    Lau DT; Hesson LB; Norris MD; Marshall G; Haber M; Ashton LJ, 2012, 'Abstract 68: Beyond GWAS: The prognostic significance of promoter DNA methylation in patients with neuroblastoma.', Cancer Epidemiology Biomarkers & Prevention, vol. 21, pp. 68 - 68, http://dx.doi.org/10.1158/1055-9965.gwas-68
    Journal articles | 2011
    Professor Michelle Haber
    Lau DTT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'HLA-G polymorphisms, genetic susceptibility, and clinical outcome in chidlhood neuroblastoma', Tissue Antigens, vol. 78, pp. 421 - 427, http://dx.doi.org/10.1111/j.1399-0039.2011.01781.x
    Journal articles | 2011
    Professor Michelle Haber
    Porro A; Iraci N; Soverini S; Diolaiti D; Gherardi S; Terragna C; Durante S; Valli E; Kalebic T; Bernardoni R; Perrod C; Haber M; Norris MD; Baccarani M; Martinelli G; Perini G, 2011, 'c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34(+) Hematopoietic Progenitor Cells', Molecular Cancer Research, vol. 9, pp. 1054 - 1066, http://dx.doi.org/10.1158/1541-7786.MCR-10-0510
    Journal articles | 2011
    Professor Michelle Haber
    Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, vol. 7, pp. e1 - e14, http://dx.doi.org/10.1371/journal.pgen.1002135
    Journal articles | 2011
    Professor Michelle Haber
    Pajic M; Murray JE; Marshall GM; Cole SPC; Norris MD; Haber M, 2011, 'ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript', Pharmacogenetics and Genomics, vol. 21, pp. 270 - 279, http://dx.doi.org/10.1097/FPC.00b013e328343dd5f
    Journal articles | 2011
    Professor Michelle Haber
    Henderson M; Haber M; Porro A; Munoz M; Xue C; Murray JE; Flemming C; Smith J; Fletcher JI; Gherardi S; Kwek C; Russell AJ; Valli E; London WB; Buxton AB; Ashton LJ; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Norris MD, 2011, 'ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux', Journal of the National Cancer Institute, vol. 103, pp. 1236 - 1251, http://dx.doi.org/10.1093/jcni/djr256
    Journal articles | 2011
    Professor Michelle Haber
    Bailey HD; Armstrong BK; de Klerk NH; Fritschi L; Attia J; Scott RJ; Smibert E; Milne E, 2011, 'Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia', INTERNATIONAL JOURNAL OF CANCER, vol. 129, pp. 1678 - 1688, http://dx.doi.org/10.1002/ijc.25769
    Journal articles | 2011
    Professor Michelle Haber
    Bailey HD; Milne E; de Klerk NH; Fritschi L; Attia J; Cole C; Armstrong BK, 2011, 'Exposure to house painting and the use of floor treatments and the risk of childhood acute lymphoblastic leukemia', INTERNATIONAL JOURNAL OF CANCER, vol. 128, pp. 2405 - 2414, http://dx.doi.org/10.1002/ijc.25572
    Journal articles | 2011
    Professor Michelle Haber
    Milne E; Royle JA; Bennett LC; de Klerk NH; Bailey HD; Bower C; Miller M; Attia J; Scott RJ; Kirby M; Armstrong BK, 2011, 'Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control study', CANCER CAUSES & CONTROL, vol. 22, pp. 207 - 218, http://dx.doi.org/10.1007/s10552-010-9688-1
    Journal articles | 2011
    Professor Michelle Haber
    Neiron Z; Jankowski K; Murray J; Champion S; Norris MD; Haber M; Fletcher JI, 2011, 'Development of organ-selective neuroblastoma cell lines to identify genes mediating bone marrow and liver colonization', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-5237
    Journal articles | 2010
    Professor Michelle Haber
    Liu T, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, vol. 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340
    Journal articles | 2010
    Professor Michelle Haber
    Milne E; Royle JA; Miller M; Bower C; de klerk NH; Bailey HD; Van brockxmeer F; Attia J; Scott RJ; Norris MD; Haber M; Thompson JR; Fritschi L; Marshall GM; Armstrong B, 2010, 'Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring', International Journal of Cancer, vol. 126, pp. 2690 - 2699, http://dx.doi.org/10.1002/ijc.24969
    Journal articles | 2010
    Professor Michelle Haber
    Swarbrick A; Woods SL; Shaw A; Balakrishnan A; Phua Y; Nguyen A; Chanthery Y; Lim L; Ashton LJ; Judson RL; Blelloch R; Huskey N; Haber M; Norris MD; Lengyel P; Hackett CS; Preiss T; Chetcuti A; Sullivan CS; Marcusson EG; Weiss W; L''Etoile N; Goga A, 2010, 'miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma', Nature Medicine, vol. 16, pp. 1134 - 1141, http://dx.doi.org/10.1038/nm.2227
    Journal articles | 2010
    Professor Michelle Haber
    Fletcher JI; Haber M; Henderson M; Norris MD, 2010, 'ABC transporters in cancer: more than just drug efflux pumps', Nature Reviews Cancer, vol. 10, pp. 147 - 156, http://dx.doi.org/10.1038/nrc2789
    Journal articles | 2010
    Professor Michelle Haber
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, vol. 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332
    Journal articles | 2010
    Professor Michelle Haber
    Porro A; Haber M; Diolaiti D; Iraci N; Henderson M; Gherardi S; Valli E; Munoz M; Xue C; Flemming C; Schwab M; Wong JH; Marshall GM; Della valle G; Norris MD; Perini G, 2010, 'Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells', The Journal of Biological Chemistry, vol. 285, pp. 19532 - 19543, http://dx.doi.org/10.1074/jbc.M109.078584
    Journal articles | 2010
    Professor Michelle Haber
    Liu T, 2010, 'Opposing Effects of Two Tissue Transglutaminase Protein Isoforms in Neuroblastoma Cell Differentiation', The Journal of Biological Chemistry, vol. 285, pp. 3561 - 3567, http://dx.doi.org/10.1074/jbc.M109.053041
    Journal articles | 2010
    Professor Michelle Haber
    Bhadri V; McGregor MR; Venn NC; Hackenberg N; Russell SJ; Norris MD; Haber M; Sutton R; Marshall GM, 2010, 'Isolated testicular relapse after allo-SCT in boys with ALL: outcome without second transplant', Bone Marrow Transplantation, vol. 45, pp. 397 - 399, http://dx.doi.org/10.1038/bmt.2009.138
    Journal articles | 2009
    Professor Michelle Haber
    Thomas WD; Chen J; Gao YR; Cheung BB; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM, 2009, 'Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression', Oncogene, vol. 28, pp. 1605 - 1615, http://dx.doi.org/10.1038/onc.2009.3
    Journal articles | 2009
    Professor Michelle Haber
    Raif A; Marshall GM; Bell J; Koach J; Tan O; D'andreti C; Thomas WD; Sekyere E; Norris MD; Haber M; Kavallaris M; Cheung BB, 2009, 'The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation', Cancer Letters, vol. 277, pp. 82 - 90, http://dx.doi.org/10.1016/j.canlet.2008.11.030
    Journal articles | 2009
    Professor Michelle Haber
    Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, vol. 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225
    Journal articles | 2009
    Professor Michelle Haber
    Ashton LJ; Gifford AJ; Kwan E; Lingwood A; Lau DTT; Marshall GM; Haber M; Norris MD, 2009, 'Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia', Leukemia, vol. 23, pp. 1348 - 1351, http://dx.doi.org/10.1038/leu.2009.67
    Journal articles | 2009
    Professor Michelle Haber
    Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; London WB; Cohn SL; Pearson ADJ; Maris JM, 2009, 'International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee', British Journal of Cancer, vol. 100, pp. 1471 - 1482, http://dx.doi.org/10.1038/sj.bjc.6605014
    Journal articles | 2009
    Professor Michelle Haber
    Dilda P; Decollogne SM; Weerakoon L; Norris MD; Haber M; Allen JD; Hogg PJ, 2009, 'Optimization of the antitumor efficacy of a synthetic mitochondrial toxin by increasing the residence time in the cytosol', Journal of Medicinal Chemistry, vol. 52, pp. 6209 - 6216, http://dx.doi.org/10.1021/jm9008339
    Journal articles | 2009
    Professor Michelle Haber
    Liu T, 2009, 'Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors', European Journal of Cancer, vol. 45, pp. 1846 - 1854, http://dx.doi.org/10.1016/j.ejca.2009.03.002
    Journal articles | 2009
    Professor Michelle Haber
    Sutton R; Venn NC; Tolisano J; Bahar AY; Giles JE; Ashton LJ; Teague L; Rigutto G; Waters K; Marshall GM; Haber M; Norris MD; Giles J, 2009, 'Clinical significance of minimal residual disease at day 15 and at the end of therapy in childhood acute lymphoblastic leukaemia', British Journal of Haematology, vol. 146, pp. 292 - 299, http://dx.doi.org/10.1111/j.1365-2141.2009.07744.x
    Journal articles | 2009
    Professor Michelle Haber
    Burkhart CA; Watt F; Murray J; Pajic M; Prokvolit A; Xue C; Flemming C; Smith J; Purmal A; Isachenko N; Komarov PG; Gurova KV; Sartorelli AC; Marshall GM; Norris MD; Gudkov AV; Haber M, 2009, 'Small-Molecule Multidrug Resistance-Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma', Cancer research, vol. 69, pp. 6573 - 6580, http://dx.doi.org/10.1158/0008-5472.CAN-09-1075
    Journal articles | 2009
    Professor Michelle Haber
    Bohlken A; Cheung B; Bell J; Koach J; Smith S; Sekyere E; Thomas WD; Norris MD; Haber M; Lovejoy DB; Richardson DR; Marshall GM, 2009, 'ATP7A is a novel target of retinoic acid receptor beta(2) in neuroblastoma cells', British Journal of Cancer, vol. 100, pp. 96 - 105, http://dx.doi.org/10.1038/sj.bjc.6604833
    Journal articles | 2009
    Professor Michelle Haber
    Brisco MJ; Latham S; Sutton R; Hughes E; Wilczek V; Van Zanten K; Budgen B; Malec M; Sykes PJ; Kuss BJ; Waters K; Venn NC; Giles J; Haber M; Norris MD; Marshall GM; Morley AA; Bahar ; Giles J, 2009, 'Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia', Journal of Molecular Diagnostics, vol. 11, pp. 194 - 200, http://dx.doi.org/10.2353/jmoldx.2009.080047
    Journal articles | 2009
    Professor Michelle Haber
    Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; London WB; Cohn SL; Pearson ADJ; Maris JM, 2009, 'International consensus for neuroblastoma molecular diagnostics: Report from the international neuroblastoma risk grouping (INRG) Biology committee', Klinische Pädiatrie, vol. 221, http://dx.doi.org/10.1055/s-0029-1222622
    Journal articles | 2008
    Professor Michelle Haber
    Williams BB; Wall M; Miao RY; Williams B; Bertoncello I; Kershaw MH; Mantamadiotis T; Haber M; Norris MD; Gautam A; Darcy PK; Ramsay RG, 2008, 'Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer', Cancer Immunology and Immunotherapy, vol. 57, pp. 1635 - 1645, http://dx.doi.org/10.1007/s00262-008-0497-2
    Journal articles | 2008
    Professor Michelle Haber
    Smith DJ; Cossins LR; Hatzinisiriou I; Haber M; Nagley P, 2008, 'Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines.', BMC Cancer, vol. 8, pp. 259, http://dx.doi.org/10.1186/1471-2407-8-251
    Journal articles | 2008
    Professor Michelle Haber
    Henderson M; Choi S; Beesley A; Sutton R; Venn NC; Marshall GM; Kees UR; Haber M; Norris MD, 2008, 'Mechanism of relapse in pediatric acute lymphoblastic leukemia', Cell Cycle, vol. 7, pp. 1315 - 1320, http://dx.doi.org/10.4161/cc.7.10.5885
    Journal articles | 2008
    Professor Michelle Haber
    Hogarty MD; Norris MD; Davis K; Liu X; Evangeliou NF; Hayes CS; Pawel B; Guo R; Zhao H; Sekyere E; Keating J; Thomas WD; Cheng NC; Murray JE; Smith J; Sutton R; Venn NC; London WB; Buxton A; Gilmour SK; Marshall GM; Haber M, 2008, 'ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma', Cancer research, vol. 68, pp. 9735 - 9745, http://dx.doi.org/10.1158/0008-5472.CAN-07-6866
    Journal articles | 2008
    Professor Michelle Haber
    Sutton R; Kwan EN; Giles JE; Venn NC; Tran S; Hackenberg N; Dalla Pozza L; Marshall GM; Haber M; van der Velden V; Norris MD; Bahar ; Giles J, 2008, 'Improving minimal residual disease detection in precursor B-ALL based on immunoglobulin-j and heavy-chain gene rearrangements', Leukemia, vol. 22, pp. 2265 - 2267, http://dx.doi.org/10.1038/leu.2008.121
    Journal articles | 2008
    Professor Michelle Haber
    Sutton R; Lonergan MA; Tapp H; Venn NC; Haber M; O Brien T; Alvaro F; Revesz T; Norris MD, 2008, 'Two cases of hypereosinophilia and high-risk acute lymphoblastic leukemia', Leukemia, vol. 22, pp. 1463 - 1465, http://dx.doi.org/10.1038/sj.leu.2405096
    Journal articles | 2008
    Professor Michelle Haber
    Henderson M; Choi S; Beesley A; Baker DL; Wright DC; Papa R; Murch A; Campbell L; Lock RB; Norris MD; Haber M; Kees UR, 2008, 'A xenograft model of infant leukaemia reveals a complex MLL translocation', British Journal of Haematology, vol. 140, pp. 716 - 719, http://dx.doi.org/10.1111/j.1365-2141.2007.06966.x
    Journal articles | 2007
    Professor Michelle Haber
    Liu T, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 18682 - 18687, http://dx.doi.org/10.1073/pnas.0705524104
    Journal articles | 2007
    Professor Michelle Haber
    Munoz MA; Henderson M; Haber M; Norris MD, 2007, 'Role of the MRP1/ABCC1 multidrug transporter protein in cancer', IUBMB Life, vol. 59, pp. 752 - 757, http://dx.doi.org/10.1080/15216540701736285
    Journal articles | 2007
    Professor Michelle Haber
    Choi S; Henderson M; Kwan EN; Sutton R; Giles J; Venn NC; Marshall GM; Haber M; Norris MD; Giles J, 2007, 'Relapse in children with acute lymphoblastic leukaemia involving selection of a pre-existing drug resistant subclone', Blood, vol. 110, pp. 632 - 639, http://dx.doi.org/10.1182/blood-2007-01-067785
    Journal articles | 2007
    Professor Michelle Haber
    Cheng AJ; Cheng NC; Smith J; Murray JE; Flemming C; Marshall GM; Norris MD; Haber M, 2007, 'Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma', European Journal of Cancer, vol. 43, pp. 1467 - 1475, http://dx.doi.org/10.1016/j.ejca.2007.03.008
    Journal articles | 2007
    Professor Michelle Haber
    Xue C; Haber M; Flemming C; Marshall GM; Lock RB; Mackenzie K; Norris MD; Gurova K; Gudkov A, 2007, 'p53 determines multidrug sensitivity of childhood neuroblastoma.', Cancer research, vol. 67, pp. 10351 - 10360, http://dx.doi.org/10.1158/0008-5472.CAN-06-4345
    Journal articles | 2007
    Professor Michelle Haber
    Liu T, 2007, 'Enhancing the anti-angiogenic action of histone deacetylase inhibitors', Molecular Cancer, vol. 6, pp. 68 - 79, http://dx.doi.org/10.1186/1476-4598-6-68
    Journal articles | 2007
    Professor Michelle Haber
    Ashton LJ; Murray JE; Haber M; Marshall GM; Norris MD; Ashley DM, 2007, 'Polymorphisms in genes encoding drug metabolising enzymes and their influence on the outcome of children with neuroblastoma.', Pharmacogenetics and Genomics, vol. 17, pp. 709 - 717, http://dx.doi.org/10.1097/FPC.0b013e3280e1cc92
    Journal articles | 2007
    Professor Michelle Haber
    Norris MD; Smith J; Kwek A; Flemming C; Cohn SL; London WB; Buxton A; Marshall GM; Haber M, 2007, 'Expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3, and ABCC4/MRP4 are powerful predictors of clinical outcome in childhood neuroblastoma', Journal of Clinical Oncology, vol. 25, pp. 9524 - 9524, http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9524
    Journal articles | 2007
    Professor Michelle Haber
    Ambros PF; Ambros IM; Brodeur GM; Haber M; Khan J; Nakagawara A; Schleiermacher G; Speleman F; Spitz R; Maris JM, 2007, '181 INVITED International consensus for neuroblastoma molecular diagnostics: report from the international neuroblastoma risk grouping (INRG) biology committee', European Journal of Cancer Supplements, vol. 5, pp. 48 - 48, http://dx.doi.org/10.1016/s1359-6349(07)70295-1
    Journal articles | 2007
    Professor Michelle Haber
    Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Science of the United States of America (November 20, 2007) 104; 47, (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 21021, http://dx.doi.org/10.1073/pnas.0711060105
    Journal articles | 2006
    Professor Michelle Haber
    Haber M; Smith J; Bordow SB; Flemming C; Cohn SL; London WB; Marshall GM; Norris MD, 2006, 'Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma', Journal of Clinical Oncology, vol. 24, pp. 1546 - 1553, http://dx.doi.org/10.1200/JCO.2005.01.6196
    Journal articles | 2006
    Professor Michelle Haber
    Cheung BB; Bell J; Raif A; Bohlken A; Yan J; Poljak A; Smith S; Lee M; Thomas WD; Kavallaris M; Norris MD; Haber M; Liu H; Zajchowski D; Marshall GM; bell , 2006, 'The estrogen-responsive B box protein is a novel regulator of the retinoid signal', The Journal of Biological Chemistry, vol. 281, pp. 18246 - 18256, http://dx.doi.org/10.1074/jbc.M600879200
    Journal articles | 2006
    Professor Michelle Haber
    Murray J; Burkhart CA; Watt F; Pajic M; Flemming C; Smith J; Gudkov AV; Haber M; Norris MD, 2006, '169 POSTER Sensitisation of neuroblastoma tumours to chemotherapy by use of a novel class of MRP1 small molecule inhibitor', European Journal of Cancer Supplements, vol. 4, pp. 54 - 54, http://dx.doi.org/10.1016/s1359-6349(06)70175-6
    Journal articles | 2005
    Professor Michelle Haber
    Laughton SJ; Ashton LJ; Kwan EN; Norris MD; Haber M; Marshall GM, 2005, 'Early responses to chemotherapy of normal and malignant hematologic cells are prognostic in childhood acute lymphoblastic leukaemia', Journal of Clinical Oncology, vol. 23, pp. 2264 - 2271, http://dx.doi.org/10.1200/JCO.2005.04.012
    Journal articles | 2005
    Professor Michelle Haber
    Liu T, 2005, 'The retinoid anticancer signal: mechanisms of target gene regulation', British Journal of Cancer, vol. 93, pp. 310 - 318, http://dx.doi.org/10.1038/sj.bjc.6602700
    Journal articles | 2005
    Professor Michelle Haber
    Norris MD; Smith J; Tanabe K; Tobin P; Flemming C; Scheffer G; Wielinga P; Cohn SL; London WB; Marshall GM; Allen JA; Haber M, 2005, 'Expression of multidrug ptransporter MRP4/ABCC4 is a marker of poor prognosis in nueroblastoma and confers resistance to irinotecan in vitro', Molecular Cancer Therapeutics, vol. 4, pp. 547 - 553, http://dx.doi.org/10.1158/1535-7163.MCT-04-0161
    Journal articles | 2005
    Professor Michelle Haber
    Pajic M; Norris MD; Cohn RJ; Haber M, 2005, 'The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome', Cancer Letters, vol. 228, pp. 241 - 246, http://dx.doi.org/10.1016/j.canlet.2005.01.060
    Journal articles | 2005
    Professor Michelle Haber
    Norris MD; Smith J; Tanabe K; Tobin P; Flemming C; Scheffer G; Wielinga P; Cohn SL; London WB; Marshall GM; Allen JA; Haber M, 2005, 'Expression of multi-drug transport MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro', Molecular Cancer Therapeutics, vol. 4, pp. 547 - 553
    Journal articles | 2004
    Professor Michelle Haber
    Don S; Verrills NM; Liaw T; Haber M; Norris MD; Kavallaris M, 2004, 'Neuronal-associated microtubule proteins class III B-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs.', Molecular Cancer Therapeutics, vol. 3, pp. 1137 - 1146
    Journal articles | 2004
    Professor Michelle Haber
    Lastowska M; Chung Y; Ching Cheng C; Haber M; Norris MD; Kees UR; Pearson AA; Jackson M, 2004, 'Regions syntenic to human 17q are gained in mouse and rat neuroblastoma.', Genes Chromosomes and Cancer, vol. 40, pp. 158 - 163, http://dx.doi.org/10.1002/gcc.20031
    Journal articles | 2004
    Professor Michelle Haber
    Hansford LM; Thomas WD; Keating JM; Burkhart C; Armati PJ; Weiss WA; Peaston AE; Norris MD; Haber M; Marshall GM, 2004, 'Mechanisms of embryonal tumor initination: Distinct roles for MycN expression and MYCN amlification.', Proceedings of the National Academy of Sciences of the United States of America, vol. 101, pp. 12664 - 12669, http://dx.doi.org/10.1073/pnas.0401083101
    Journal articles | 2004
    Professor Michelle Haber
    Liem N; Papa R; Milross CG; Schmid M; Tajbakhsh M; Choi S; Ramirez C; Rice AM; Haber M; Norris MD; Lock RB, 2004, 'Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies', Blood, vol. 103, pp. 3905 - 3914, http://dx.doi.org/10.1182/blood-2003-08-2911
    Journal articles | 2004
    Professor Michelle Haber
    Manohar CF; Bray JA; Salwen H; Madafiglio J; Cheng AJ; Flemming C; Marshall GM; Norris MD; Haber M; Cohn SL, 2004, 'MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma', Oncogene, vol. 23, pp. 753 - 762, http://dx.doi.org/10.1038/sj.onc.1207151
    Journal articles | 2003
    Professor Michelle Haber
    Marshall GM; Haber M; Kwan EN; Zhu L; Ferrara D; Xue C; Brisco MJ; Sykes PJ; Morley A; Webster B; Dalla Pozza L; Waters K; Norris MD, 2003, 'Importance of minimal residual disease testing during teh second year of therapy for children with acute lymphoblastic leukemia', Journal of Clinical Oncology, vol. 21, pp. 704 - 709, http://dx.doi.org/10.1200/JCO.2003.10.080
    Journal articles | 2003
    Professor Michelle Haber
    Nguyen TG; Hocker JE; Thomas WD; Smith SA; Norris MD; Haber M; Cheung BB; Marshall GM, 2003, 'Combined RAR and RXr-specific ligands overcome N-myc-associated retinoid resistance in neuroblastoma cells', Biochemical and Biophysical Research Communications, vol. 302, pp. 462 - 468, http://dx.doi.org/10.1016/S0006-291X(03)00177-3
    Journal articles | 2003
    Professor Michelle Haber
    Burkhart CA; Cheng AJ; Madafiglio J; Kavallaris M; Mili M; Marshall GM; Weiss WA; Khachigian LM; Norris MD; Haber M, 2003, 'Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma', Journal of National Cancer Institute, vol. 95, pp. 1394 - 1403, http://dx.doi.org/10.1093/jnci/djg045
    Journal articles | 2003
    Professor Michelle Haber
    Verrills NM; Flemming C; Liu M; Ivery M; Cobon GS; Norris MD; Haber M; Kavallaris M, 2003, 'Microtubule alterations and mutations induced by desoxyepothilone B: Implications for drug-target', Chemistry and biology, vol. 10, pp. 597 - 607, http://dx.doi.org/10.1016/S1074-5521(03)00141-8
    Journal articles | 2003
    Professor Michelle Haber
    Pearson AJ; Haber M; Norris MD; Xue C; Flemming C; Lunec J; Tweddle D, 2003, 'The p53 pathway and its inactivitation in neuroblastoma', Cancer Letters, vol. 197, pp. 93 - 98, http://dx.doi.org/10.1016/S0304-3835(03)00088-0
    Journal articles | 2003
    Professor Michelle Haber
    Hansford LM; Smith S; Haber M; Norris MD; Cheung BB; Marshall GM, 2003, 'Cloning and characterisation of the human neural cell adhesion molecule, (CNTN4) ( alias BIG-2)', Cytogenetic and Genome Research, vol. 101, pp. 1 - 17, http://dx.doi.org/10.1159/000073412
    Journal articles | 2003
    Professor Michelle Haber
    Cheung BB; Yan JX; Smith SA; Nguyen TG; Lee M; Kavallaris M; Norris MD; Haber M; Marshall GM, 2003, 'Growth inhibitory retinoid effects after recruitment of retinoid X receptor B to the retinoic acid receptor B promoter', International Journal of Cancer, vol. 105, pp. 856 - 867, http://dx.doi.org/10.1002/ijc.11153
    Journal articles | 2003
    Professor Michelle Haber
    Marshall G; Norris M; Haber M, 2003, 'In Reply:', Journal of Clinical Oncology, vol. 21, pp. 4464 - 4465, http://dx.doi.org/10.1200/jco.2003.99.188
    Journal articles | 2002
    Professor Michelle Haber
    Lock RB; Liem N; Farnsworth ML; Milross CG; Xue C; Tajbakhsh M; Haber M; Norris MD; Marshall GM; Rice AM, 2002, 'The non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of Childhood acute lymphblastic leukemia reveals intrinsic differences in biological characteristics at diagnosis and relapse', Blood, vol. 99, pp. 4100 - 4108, http://dx.doi.org/10.1182/blood.V99.11.4100
    Journal articles | 2002
    Professor Michelle Haber
    Gifford AJ; Haber M; Witt T; Whetstine JR; Taub JW; Matherly LH; Norris MD, 2002, 'Role of E45K reduced folate carrier gene mutation in methotrexate resistance in human leukaemia cells', Leukemia, vol. 16, pp. 2379 - 2387, http://dx.doi.org/10.1038/sj.leu.2402655
    Journal articles | 2002
    Professor Michelle Haber
    Efferth T; Verdorfer I; Miyachi H; Sauerbrey A; Drexler H; Chitambar C; Haber M; Gebhart E, 2002, 'Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines', Blood Cells Molecules and Diseases, vol. 29, pp. 1 - 13, http://dx.doi.org/10.1006/bcmd.2002.0530
    Journal articles | 2002
    Professor Michelle Haber
    Houghton PJ; Adamson PC; Blaney S; Fine HA; Gorlick R; Haber M; Helman L; Hirschfeld S; Hollingshead MG; Israel MA; Lock RB; Maris JM; Merlino G; Patterson W; Reynolds CP; Shannon K; Yu A; Yu J; Smith MA, 2002, 'Testing of new agents in childhood cancer preclinical models(meeting summary)', Clinical Cancer Research, vol. 8, pp. 3646 - 3657
    Journal articles | 2002
    Professor Michelle Haber
    Burkhart CA; Norris MD; Haber M, 2002, 'A simple method for the isolation of genomic DNA from mouse tail free of real-time PCR inhibitors', Journal of Biochemical and Biophysical Methods, vol. 52, pp. 145 - 149, http://dx.doi.org/10.1016/S0165-022X(02)00052-0
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Madafiglio J; Gilbert J; Marshall GM; Haber M, 2001, 'Relationship between histopathological features, MYCN amplification, and prognosis: A UKCCSG study', Medical and Pediatric Oncology, vol. 36, pp. 169 - 176, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<169::AID-MPO1041>3.0.CO;2-U
    Journal articles | 2001
    Professor Michelle Haber
    Whetstine JR; Gifford AJ; Witt T; Liu X; Flatley RM; Norris MD; Haber M; Taub JW; Ravindranath Y; Matherly LH, 2001, 'Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G.A variant at position 80 and transport properties of the his27 And Arg27 carriers', Clinical Cancer Research, vol. 7, pp. 3416 - 3422, http://clincancerres.aacrjournals.org/content/7/11/3416.full-text.pdf
    Journal articles | 2001
    Professor Michelle Haber
    Marshall GM; Norris MD; Lock RB; Peaston AE; Gardaneh M; Franco VA; Hocker JE; Murphy K; Farnsworth ML; Catchpoole DR; Haber M, 2001, 'MRP1 gene expression level regulates the death and differentation response of neuroblastoma cells', British Journal of Cancer, vol. 85, pp. 1564 - 1571, http://dx.doi.org/10.1054/bjoc.2001.2144
    Journal articles | 2001
    Professor Michelle Haber
    Kavallaris M; Tait AS; Norris MD; Haber M; Walsh B; He L; Horwitz SB, 2001, 'Multiple microtubule alterations are associated with vinca alkaloid resistance in human leukemia cells', Cancer research, vol. 61, pp. 5803 - 5809
    Journal articles | 2001
    Professor Michelle Haber
    Catts VS; Haber M; Norris MD; Lutze-Mann L; Lock RB, 2001, 'High Level resistance to Glucocorticoids, assosiated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance', Leukemia, vol. 15, pp. 929 - 935, http://dx.doi.org/10.1038/sj.leu.2402128
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Madafiglio J; Gilbert J; Marshall GM; Haber M, 2001, 'Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin', MEDICAL AND PEDIATRIC ONCOLOGY, vol. 36, pp. 177 - 180, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<177::AID-MPO1042>3.0.CO;2-Q
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Gilbert J; Smith SA; Marshall GM; Salwen H; Cohn SL; Haber M, 2001, 'Genomic and allelic expression status of the p73 gene in human neuroblastoma', Medical and Pediatric Oncology, vol. 36, pp. 45 - 47, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<45::AID-MPO1012>3.0.CO;2-E
    Journal articles | 2001
    Professor Michelle Haber
    Kwan E; Lal A; Haber M; Norris MD; Marshall GM, 2001, 'Detection of minimal residual disease in peripheral blood prior to clonical relapse of childhood acute lympohoblastic leukaemia using PCR', Molecular and Cellular Probes, vol. 15, pp. 99 - 103, http://dx.doi.org/10.1006/mcpr.2001.0348
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Gilbert J; Smith A; Marshall GM; Salwen H; Cohn JN; Haber M, 2001, 'Expression of the Putative Tumour Suppressor Gene, p73, in Neuroblastome and Other Childhood Tumours', Medical Pediatric Oncology, vol. 36, pp. 48 - 51, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<48::AID-MPO1013>3.0.CO;2-8
    Journal articles | 2001
    Professor Michelle Haber
    Ekert H; Vivekanandan S; Chow CW; Marshall GM; Haber M; Norris MD, 2001, 'Expression of GAGE genes in neuroblastoma by reverse transcription - polymerase chain reaction', Cancer Research Therapy and Control, vol. 11, pp. 197 - 203
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Marshall GM; Haber M; Gilbert J; Madafiglio J, 2001, 'Reversal of MRP-mediated drug resistance in cultured human neuroblastome cells by the quinlone antibiotic, difloxacin', Medical Pediatric Oncology, pp. 177 - 180
    Journal articles | 2001
    Professor Michelle Haber
    Norris MD; Gilbert J; Smith SA; Marshall GM; Salwen H; Cohn SL; Haber M, 2001, 'Expression of the putative tumour suppressor gene, p73, in neuroblastoma and other childhood tumours', Medical and Pediatric Oncology, vol. 36, pp. 48 - 51, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<48::AID-MPO1013>3.0.CO;2-8
    Journal articles | 2000
    Professor Michelle Haber
    Cohn S; London WB; Huang K; Katzenstein HM; Salwen H; Reinhart T; Madafiglio J; Marshall GM; Norris MD; Haber M, 2000, 'MYCN expression is not prognostic of adverse outcomes in advanced-stage neuroblastoma with non-amplified MYCN', Journal of Clinical Oncology, vol. 18, pp. 3604 - 3613, http://dx.doi.org/10.1200/JCO.2000.18.21.3604
    Journal articles | 2000
    Professor Michelle Haber
    Norris MD; Burkhart CA; Marshall GM; Haber M, 2000, 'Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in murine neuroblastoma model', Medical and Pediatric Oncology, vol. 35, pp. 585 - 589, http://dx.doi.org/10.1002/1096-911X(20001201)35:6<585::AID-MPO20>3.0.CO;2-P
    Journal articles | 2000
    Professor Michelle Haber
    Kwan EN; Norris MD; Zhu L; Ferrara D; Marshall GM; Haber M, 2000, 'Simultaneous detection and quantification of minimal residual disease in childhood acute lymphoblastic leukaemia using real-time polymerase chain reaction', British Journal of Haematology, vol. 109, pp. 430 - 434, http://dx.doi.org/10.1046/j.1365-2141.2000.02029.x
    Journal articles | 2000
    Professor Michelle Haber
    Gardaneh M; Gilbert J; Haber M; Norris MD; Marshall GM, 2000, 'Synergy between 5` and 3` flanking regions of the human tyrosine hydroxylase gene ensures specific, high-level expression in neuroblastoma cells', Neuroscience Letters, vol. 292, pp. 147 - 150, http://dx.doi.org/10.1016/S0304-3940(00)01474-9
    Journal articles | 1999
    Professor Michelle Haber
    Gilbert J; Haber M; Bordow SB; Marshall GM; Norris MD, 1999, 'Use of tumor-specific gene expression for the differential diagnosis of neuroblastoma from other pediatric small-round-cell malignancies', American Journal of Pathology, vol. 155, pp. 17 - 21, http://dx.doi.org/10.1016/S0002-9440(10)65093-6
    Journal articles | 1999
    Professor Michelle Haber
    Marshall GM; Haber M; Kwan E; Zhou L; Ferrara D; Williams S; Brisco MJ; Morley A; Webster B; Dalla Pozza L; Tucker D; Waters K; Norris MD, 1999, 'The effect of late intensification of therapy in children with acute lymphoblastic leukaemia and minimal residual disease.', BLOOD, vol. 94, pp. 658A - 658A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790302970&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1999
    Professor Michelle Haber
    Haber M; Bordow SB; Gilbert J; Madafiglio J; Kavallaris M; Marshall GM; Mechetner EB; Fruehauf JP; Tee L; Cohn S; Salwen H; Schmidt ML; Norris MD; Gilbert J, 1999, 'Altered expression of the MYCN Oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells', Oncogene, vol. 18, pp. 2777 - 2782, http://dx.doi.org/10.1038/sj.onc.1202859
    Journal articles | 1998
    Professor Michelle Haber
    Gifford AJ; Kavallaris M; Madafiglio J; Matherly LH; Stewart BW; Haber M; Norris MD, 1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, vol. 78, pp. 176 - 181, http://dx.doi.org/10.1002/(SICI)1097-0215(19981005)78:2<176::AID-IJC10>3.0.CO;2-9
    Journal articles | 1998
    Professor Michelle Haber
    Bardow SB; Norris MD; Haber PS; Marshall GM; Haber M, 1998, 'Prognostic significance of MYCN oncgene expression in childhood neuroblastoma', Journal of Clinical Oncology, vol. 16, pp. 3286 - 3294, http://dx.doi.org/10.1200/JCO.1998.16.10.3286
    Journal articles | 1998
    Professor Michelle Haber
    Cheung BB; Hocker JE; Smith S; Norris MD; Haber M; Marshall GM, 1998, 'Favorable prognostic signifiance of high-level retinoic acid receptor B expression in neuroblastoma mediated by effects on cell cycle regulation', Oncogene, vol. 17, pp. 751 - 759, http://dx.doi.org/10.1038/sj.onc.1201982
    Journal articles | 1998
    Professor Michelle Haber
    Preston AE; Camacho M; Norris MD; Haber M; Marsh DJ; Robinson BG; Hyland V; Marshall GM, 1998, 'Absence of MEN2A- or 2B- type RET mutations in primary neuroblastoma tumour tissue', Molecular and Cellular Probes, vol. 12, pp. 239 - 242, http://dx.doi.org/10.1006/mcpr.1998.0181
    Journal articles | 1998
    Professor Michelle Haber
    Kavallaris M; Gardaneh M; Cheung BB; Camacho M; Hocker JE; Norris MD; Haber M; Marshall GM, 1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, vol. 18, pp. 1793 - 1798
    Journal articles | 1998
    Professor Michelle Haber
    Lal A; Kwan EN; Al Mahr M; Zhou L; Ferrara D; Tobias VH; O Gorman-Hughes DW; Haber M; Norris MD; Marshall GM, 1998, 'Molecular detection of acute Lymphoblastic Leukaemia in boys with testicular relapse', Molecular Pathology, vol. 51, pp. 277 - 281, http://dx.doi.org/10.1136/mp.51.5.277
    Journal articles | 1997
    Professor Michelle Haber
    Castleberry RP; Pritchard JE; Ambros P; Berthold F; Brodeur GM; Castel V; Cohn S; Debernardi B; Dicksmireaux C; Frappaz D; Haase GM; Haber M, 1997, 'THE INTERNATIONAL NEUROBLASTOMA RISK GROUPS (INRG) - A PRELIMINARY REPORT', EUR Journal CANCER, vol. 33, pp. 2113 - 2116, http://dx.doi.org/10.1016/S0959-8049(97)00202-5
    Journal articles | 1997
    Professor Michelle Haber
    Kavallaris M; Kuo DY; Burkhart CA; Regl DL; Norris MD; Haber M; Horwitz SB, 1997, 'TAXOL-RESISTANT EPITHELIAL OVARIAN TUMORS ARE ASSOCIATED WITH ALTERED EXPRESSION OF SPECIFIC {BETA}-TUBLIN ISOTYPES', Journal of Clinical Investigation, vol. 100, pp. 1282 - 1293, http://dx.doi.org/10.1172/JCI119642
    Journal articles | 1997
    Professor Michelle Haber
    Norris MD; Bordow SB; Haber PS; Marshall GM; Kavallaris M; Madafiglio J; Cohn S; Schmidt ML; Hipfner DR; Deeley RG; Cole SP; Haber M; Salwen H, 1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, vol. 33, pp. 1911 - 1916, http://dx.doi.org/10.1016/S0959-8049(97)00284-0
    Journal articles | 1997
    Professor Michelle Haber
    Haber M; Bordow SB; Haber PS; Marshall GM; Stewart BW; Norris MD, 1997, 'THE PROGNOSTIC VALUE OF MDR1 GENE EXPRESSION IN PRIMARY UNTREATED NEUROBLASTOMA', EUR Journal CANCER, vol. 33, pp. 2031 - 2036, http://dx.doi.org/10.1016/S0959-8049(97)00229-3
    Journal articles | 1997
    Professor Michelle Haber
    Norris MD; Kwan EN; Zhu L; Ferrara D; Marshall GM; Haber M, 1997, 'IMPROVED PCR ASSAY FOR THE DETECTION OF ANTIGEN RECEPTOR GENE REARRANGEMENTS', Journal of Biochemical and Biophysical Methods, vol. 36, pp. 3 - 10, http://dx.doi.org/10.1016/S0165-022X(97)00043-2
    Journal articles | 1997
    Professor Michelle Haber
    Marshall GM; Peaston AE; Hocker JE; Smith AJ; Hansford LM; Tobias VH; Norris MD; Haber M; Smith DD; Lorenzo MJ; Ponder BJ; Hancock JF, 1997, 'Expression of multiple endocrine neoplasia 2B ret in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behaviour in vivo, and activates jun kinase 1', Cancer research, vol. 57, pp. 5399 - 5405
    Journal articles | 1997
    Professor Michelle Haber
    Haber M; Kwan EN; Zhu L; Marshall GM; Norris MD, 1997, 'SENSITIVE NON- RADIOACTIVE PCR DETECTION OF CLONAL T-CELL RECEPTOR GAMMA GENE REARRANGEMENTS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA', British Journal of Haematology, vol. 98, pp. 995 - 998, http://dx.doi.org/10.1046/j.1365-2141.1997.3243143.x
    Journal articles | 1997
    Professor Michelle Haber
    Gilbert J; Norris MD; Marshall GM; Haber M, 1997, 'Low specificity of PGP9.5 expression for detection of micrometastatic neuroblastoma', British Journal of Cancer, vol. 75, pp. 1779 - 1781, http://dx.doi.org/10.1038/bjc.1997.303
    Journal articles | 1996
    Professor Michelle Haber
    Norris MD; De Graaf D; Haber M; Kavallaris M; Madafiglio J; Gilbert J; Kwan E; Stewart BW; Mechetner EB; Gudkov AV; Roninson IB, 1996, 'Involvement of MDR1 P-Glycoprotein in multifactorial resistance to methotrexate', International Journal of Cancer, vol. 65, pp. 613 - 619, http://dx.doi.org/10.1002/(SICI)1097-0215(19960301)65:5<613::AID-IJC10>3.0.CO;2-8
    Journal articles | 1996
    Professor Michelle Haber
    Norris MD; Bordow SB; Marshall GM; Haber PS; Cohn S; Haber M, 1996, 'Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma', New England Journal of Medicine, vol. 334, pp. 231 - 238, http://dx.doi.org/10.1056/NEJM199601253340405
    Journal articles | 1996
    Professor Michelle Haber
    Cheung BB; Hocker JE; Smith SA; Reichert U; Norris MD; Haber M; Stewart BW; Marshall GM, 1996, 'Retinoic acid receptors B and g distinguish retinoid signals for growth inhibition and neuritogenesis in human neuroblastoma cells', Biochemical and Biophysical Research Communications, vol. 229, pp. 349 - 354, http://dx.doi.org/10.1006/bbrc.1996.1804
    Journal articles | 1996
    Professor Michelle Haber
    Norris MD; Bordow SB; Marshall GM; Heber PS; Cohn S; Haber M, 1996, 'Association between high levels of expression of the multidrug resistance-associated protein (MRP) gene and poor outcome in primary human neuroblastoma', New England Journal of Medicine, pp. 231 - 238
    Journal articles | 1996
    Professor Michelle Haber
    Norris MD; Kwan E; Zhu L; Marshall GM; Haber M, 1996, 'Sensitive non radioactive PCR detection of minimal residual leukaemia using TCR(gamma) gene rearrangements', BRITISH JOURNAL OF HAEMATOLOGY, vol. 93, pp. 225 - 225, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996UP11400225&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1995
    Professor Michelle Haber
    Haber M; Burkhart CA; Regl DL; Madafiglio J; Norris MD; Horwitz SB, 1995, 'Altered expression of Mβ2, the class II β-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance', Journal of Biological Chemistry, vol. 270, pp. 31269 - 31275, http://dx.doi.org/10.1074/jbc.270.52.31269
    Journal articles | 1995
    Professor Michelle Haber
    Haber M; Norris MD; Kavallaris M; Camacho M; Madafiglio J; Baker C; White L; Stewart BW, 1995, 'An assay for the determination of reduced methotrexate accumulation in cells displaying limited viability in vitro', Cancer Letters, vol. 97, pp. 49 - 55, http://dx.doi.org/10.1016/0304-3835(95)03950-2
    Journal articles | 1995
    Professor Michelle Haber
    Norris MD; Kwan EN; Haber M; Marshall GM, 1995, 'Detection of evolving immunoglobin heavy chain gene rearrangements in acute lymphoblastic leukemia: a PCR-based assay employing overlapping DHh primers', Leukemia, vol. 9, pp. 1779 - 1782
    Journal articles | 1995
    Professor Michelle Haber
    Norris MD; Gilbert J; Madafiglio J; Haber M, 1995, 'Analysis of a novel cDNA encoding a C219-reactive peptide isolated from methotrexate-selected multidrug-resistant human leukemic cells', Gene, vol. 156, pp. 313 - 314, http://dx.doi.org/10.1016/0378-1119(94)00541-Y
    Journal articles | 1995
    Professor Michelle Haber
    Marshall GM; Kwan EN; Haber M; Brisco MJ; Sykes PJ; Morley A; Toogood I; Waters K; Tauro G; Ekert H; Norris MD, 1995, 'Characterisation of clonal immunoglobulin heavy chain and T-cell receptor y gene rearrangements during progression of childhood acute lymphoblastic leukemia', Leukemia, vol. 9, pp. 1847 - 1850
    Journal articles | 1995
    Professor Michelle Haber
    Marshall GM; Cheung BB; Stacey KP; Camacho M; Simpson AM; Kwan EN; Smith S; Haber M; Norris MD, 1995, 'Increased retinoic acid receptor gamma expression suppresses the malignant phenotype and alters the differentiation potential of human neuroblastoma cells', Oncogene, vol. 11, pp. 485 - 491
    Journal articles | 1994
    Professor Michelle Haber
    Haber M; Madafiglio J; Bordow SB; Gilbert J; Cheung B; Marshall GM; Norris MD, 1994, 'Expression of retinoic acid-responsive genes in primary neuroblastomas.', Progress in clinical and biological research, vol. 385, pp. 245 - 251
    Journal articles | 1994
    Professor Michelle Haber
    Norris MD; Haber M; Gilbert J; Kavallaris M; Marshall GM; Stewart BW, 1994, 'N-myc gene amplification in neuroblastoma determined by the polymerase chain reaction.', Progress in clinical and biological research, vol. 385, pp. 27 - 33
    Journal articles | 1994
    Professor Michelle Haber
    Bordow SB; Haber M; Madaflglio J; Cheung B; Marshall GM; Norris MD, 1994, 'Expression of the Multidrug Resistance-associated Protein (MRP) Gene Correlates with Amplification and Overexpression of the N-myc Oncogene in Childhood Neuroblastoma', Cancer Research, vol. 54, pp. 5036 - 5040
    Journal articles | 1994
    Professor Michelle Haber
    MARSHALL GM; CHEUNG B; STACEY KP; NORRIS MD; HABER M, 1994, 'REGULATION OF RETINOIC ACID RECEPTOR-ALPHA EXPRESSION IN HUMAN NEUROBLASTOMA CELL-LINES AND TUMOR-TISSUE', ANTICANCER RESEARCH, vol. 14, pp. 437 - 441, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NR46300017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1994
    Professor Michelle Haber
    Marshall GM; Cheung B; Stacey KP; Norris MD; Haber M, 1994, 'Regulation of retinoic acid receptor alpha expression in human neuroblastoma cell lines and tumor tissue', Anticancer Research, vol. 14, pp. 437 - 441
    Journal articles | 1993
    Professor Michelle Haber
    Kavallaris M; Madafiglio J; Norris MD; Haber M, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, vol. 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013
    Journal articles | 1993
    Professor Michelle Haber
    Selig RA; Madafiglio J; Haber M; Norris MD; White L; Stewart BW, 1993, 'Ferritin production and desferrioxamine cytotoxicity in human neuroblastoma cell lines', Anticancer Research, vol. 13, pp. 721 - 725
    Journal articles | 1993
    Professor Michelle Haber
    Haber M; Madafiglio J; Norris MD, 1993, 'Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine', Journal of Cancer Research and Clinical Oncology, vol. 119, pp. 315 - 317, http://dx.doi.org/10.1007/BF01208836
    Journal articles | 1993
    Professor Michelle Haber
    Gilbert J; Norris MD; Haber M; Kavallaris M; Marshall GM; Stewart BW, 1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, vol. 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033
    Journal articles | 1991
    Professor Michelle Haber
    Norris MD; Haber M; Kavallaris M; Brian MJ; Lutze LH; White L; Stewart BW, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, vol. 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W
    Journal articles | 1991
    Professor Michelle Haber
    Kavallaris M; Haber M; Norris MD; Matherly LH; Stewart BW, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, vol. 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119
    Journal articles | 1990
    Professor Michelle Haber
    Kavallaris M; Haber M; Norris MD; Pittman SM; Reed C; Stewart BW, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, vol. 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4
    Journal articles | 1989
    Professor Michelle Haber
    Haber M; Norris MD; Kavallaris M; White L; Stewart BW; Bell DR; Davey RA, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, vol. 49, pp. 5281 - 5287
    Journal articles | 1989
    Professor Michelle Haber
    White L; Haber M; Brian MJ; Norris MD; Trickett A; Sosula L; Tiley C; Stewart BW, 1989, 'Therapy‐induced drug resistance in a human leukemia line (LALW‐2)', Cancer, vol. 63, pp. 2103 - 2110, http://dx.doi.org/10.1002/1097-0142(19890601)63:11<2103::AID-CNCR2820631106>3.0.CO;2-N
    Journal articles | 1989
    Professor Michelle Haber
    Haber M; Reed C; Kavallaris M; Norris MD; Stewart BW, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, vol. 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250
    Journal articles | 1989
    Professor Michelle Haber
    Norris MD; Haber M; King M; Davey RA, 1989, 'Atypical multidrug resistance in CCRF-CEM cells selected for high level methotrexate resistance: Reactivity to monoclonal antibody C219 in the absence of P-glycoprotein expression', Biochemical and Biophysical Research Communications, vol. 165, pp. 1435 - 1441, http://dx.doi.org/10.1016/0006-291X(89)92764-2
    Journal articles | 1986
    Professor Michelle Haber
    Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography - Biomedical Applications, vol. Vol. 382, pp. 127 - 134
    Journal articles | 1986
    Professor Michelle Haber
    Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography B: Biomedical Sciences and Applications, vol. 382, pp. 135 - 145, http://dx.doi.org/10.1016/S0378-4347(00)83512-4
    Journal articles | 1986
    Professor Michelle Haber
    Stewart BW; Haber M; Ward EJ, 1986, 'Digestion of repair sites in rat liver DNA by endogenous nucleases.', Biochemistry International, vol. 13, pp. 903 - 913
    Journal articles | 1986
    Professor Michelle Haber
    HABER M; KAVALLARIS M; STEWART BW, 1986, '2-STAGE INCORPORATION OF THYMIDINE TRIPHOSPHATE INTO MAMMALIAN DNA AS INDICATED BY CHROMATOGRAPHY ON BENZOYLATED DEAE-CELLULOSE', JOURNAL OF CHROMATOGRAPHY, vol. 382, pp. 127 - 134, http://dx.doi.org/10.1016/S0378-4347(00)83511-2
    Journal articles | 1985
    Professor Michelle Haber
    Haber M; Stewart BW, 1985, 'Oncogenes. A possible role for cancer genes in human malignant disease', Medical Journal of Australia, vol. 142, pp. 402 - 409, http://dx.doi.org/10.5694/j.1326-5377.1985.tb133155.x
    Journal articles | 1985
    Professor Michelle Haber
    Haber M; Stewart BW, 1985, 'Patterns of structural change in DNA during tissue necrosis indicated by benzoylated DEAE-cellulose chromatography', Chemico-Biological Interactions, vol. 53, pp. 247 - 255, http://dx.doi.org/10.1016/S0009-2797(85)80102-2
    Journal articles | 1985
    Professor Michelle Haber
    Stewart BW; Hristoforidis C; Haber M, 1985, 'Dose-dependent persistence of alkylation-induced single stranded regions in rat liver DNA in vivo', Cancer Letters, vol. 28, pp. 27 - 33, http://dx.doi.org/10.1016/0304-3835(85)90088-6
    Journal articles | 1985
    Professor Michelle Haber
    Ward EJ; Haber M; Norris MD; Stewart BW, 1985, 'Single-Strand-Specific Degradation of DNA during Isolation of Rat Liver Nuclei†', Biochemistry, vol. 24, pp. 5803 - 5809, http://dx.doi.org/10.1021/bi00342a018
    Journal articles | 1985
    Professor Michelle Haber
    Stewart BW; Hristofordis C; Haber M; Ward EJ, 1985, 'Enhancement of nitrosamine-induced structural damage in rat liver DNA by cell division', Proceedings of the American Association for Cancer Research, vol. VOL. 26
    Journal articles | 1985
    Professor Michelle Haber
    STEWART BW; HRISTOFORDIS C; HABER M; WARD EJ, 1985, 'ENHANCEMENT OF NITROSAMINE-INDUCED STRUCTURAL DAMAGE IN RAT-LIVER DNA BY CELL-DIVISION', PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 26, pp. 97 - 97, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AGD9400383&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1984
    Professor Michelle Haber
    WARD EJ; HABER M; STEWART BW, 1984, 'DIFFERENTIAL REPAIR OF ALKYLATION DAMAGE IN RAT-LIVER CHROMATIN', MEDICAL AND PEDIATRIC ONCOLOGY, vol. 12, pp. 278 - 279, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984TC60000027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1984
    Professor Michelle Haber
    Haber M; Huang PHT; Stewart BW, 1984, 'Limitations on the stability of benzoylated DEAE-cellulose', Analytical Biochemistry, vol. 139, pp. 363 - 366, http://dx.doi.org/10.1016/0003-2697(84)90018-6
    Journal articles | 1984
    Professor Michelle Haber
    STEWART BW; HABER M; HRISTOFORIDIS C, 1984, 'FACTORS AFFECTING THE PERSISTENCE OF ALKYLATION-INDUCED STRUCTURAL DAMAGE IN DNA INVIVO', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 16, pp. S18 - S18, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984ANC4600033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1983
    Professor Michelle Haber
    HABER M; STEWART BW, 1983, 'REPLICATIVE INTERMEDIATES IN MAMMALIAN DNA', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 15, pp. 69 - 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1983RC51300166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1983
    Professor Michelle Haber
    HABER M; STEWART BW, 1983, 'STRUCTURAL INTERMEDIATES GENERATED DURING REPLICATION OF MAMMALIAN DNA', MEDICAL AND PEDIATRIC ONCOLOGY, vol. 11, pp. 198 - 199, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1983QX04200045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1981
    Professor Michelle Haber
    Haber M; Stewart BW, 1981, 'Sizing of DNA fragments by preparative, benzoylated DEAE-cellulose chromatography', FEBS Letters, vol. 133, pp. 72 - 74, http://dx.doi.org/10.1016/0014-5793(81)80473-5
    Journal articles | 1981
    Professor Michelle Haber
    HABER M; STEWART BW, 1981, 'ANALYSIS OF CHEMICALLY-INDUCED STRUCTURAL-CHANGE IN DNA BY BENZOYLATED-DEAE-CELLULOSE CHROMATOGRAPHY', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 14, pp. 90 - 90, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1981LR25400218&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
  • Conference Papers | 2021
    Professor Michelle Haber
    Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2021-3044
    Conference Papers | 2021
    Professor Michelle Haber
    Vijayasubhash V, 2021, 'Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR', in Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR, presented at AACR 2021, http://dx.doi.org/10.1158/1538-7445.AM2021-639
    Conference Abstracts | 2020
    Professor Michelle Haber
    Dong-Anh K-Q; Nagabushan S; Manoharan N; Arndt G; Barahona P; Cowley MJ; Ekert PG; Failes T; Bolanos NF; Gauthier M; Gifford AJ; Haber M; Kumar A; Lock RB; Marshall GM; Mayoh C; Mould E; Norris MD; Gopalakrishnan A; Omer N; Trebilcock P; Trahair TN; Tsoli M; Tucker K; Wong M; Tyrrell V; Lau L; Ziegler DS, 2020, 'PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 302 - 302, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100118&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Professor Michelle Haber
    Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292, http://dx.doi.org/10.1093/neuonc/noaa222.076
    Conference Abstracts | 2020
    Professor Michelle Haber
    Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.065
    Conference Abstracts | 2020
    Professor Michelle Haber
    Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-SY09-02
    Conference Abstracts | 2020
    Professor Michelle Haber
    Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'DIPG-16. COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii290 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.066
    Conference Abstracts | 2020
    Professor Michelle Haber
    Atkinson C; Tactacan C; Kamili A; Saletta F; Gana C; Eden G; Mayoh C; Lock R; Norris M; Haber M; Gifford A; Trahair T; Fletcher J, 2020, 'Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a35
    Conference Abstracts | 2020
    Professor Michelle Haber
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a52
    Conference Papers | 2020
    Professor Michelle Haber
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a03
    Conference Abstracts | 2019
    Professor Michelle Haber
    Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Montreal, CANADA, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, Montreal, CANADA, 17 September 2019 - 20 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Professor Michelle Haber
    Nagy Z; Kanikevich M; Koach J; Mayoh C; Carter D; Liu T; Du Y; Jiang C; Haber M; Norris M; Cheung B; Marshall G, 2019, 'Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3659
    Conference Abstracts | 2019
    Professor Michelle Haber
    Nagy Z; Kanikevichi M; Koachi J; Mayoh C; Carter D; Liu T; Du Y; Jiang C; Haber M; Norris M; Cheung B; Marshall G, 2019, 'Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3659
    Conference Papers | 2019
    Professor Michelle Haber
    Valli E; Xue C; Cheung L; Gamble L; Pandher R; Di Giacomo S; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2616
    Conference Abstracts | 2019
    Professor Michelle Haber
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Abstract 2884: Establishment of patient-derived xenograft models for high-risk neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2884
    Conference Abstracts | 2019
    Professor Michelle Haber
    Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3111
    Conference Abstracts | 2019
    Professor Michelle Haber
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Abstract 4741: Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.am2019-4741
    Conference Papers | 2019
    Professor Michelle Haber
    Valli E; Xue C; Cheung L; Gamble L; Pandher R; Giacomo SD; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2616
    Conference Abstracts | 2019
    Professor Michelle Haber
    Atkinson C; Tactacan C; Kamili A; Saletta F; Gana C; Eden G; Mayoh C; Lock R; Norris M; Haber M; Gifford A; Trahair T; Fletcher J, 2019, 'P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Montreal, CANADA, Vol. 80, pp. 61 - 61, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, Montreal, CANADA, 17 September 2019 - 20 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Professor Michelle Haber
    Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3809
    Conference Papers | 2019
    Professor Michelle Haber
    Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.am2019-3809
    Conference Abstracts | 2019
    Professor Michelle Haber
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-4741
    Conference Abstracts | 2019
    Professor Michelle Haber
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Establishment of patient-derived xenograft models for high-risk neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2884
    Conference Abstracts | 2019
    Professor Michelle Haber
    Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O'Brien T; Dong AKQ; Cowley M; Ekert P; Ziegler DS, 2019, 'RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRA-TM PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, San Francisco, CA, Vol. 21, pp. 118 - 118, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, San Francisco, CA, 03 May 2019 - 04 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000473243700229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Professor Michelle Haber
    Tee AE; Liu PY; Milazzo G; Hannan KM; Maag J; Bartonicek N; Song R; Jiang CC; Zhang XD; Norris MD; Haber M; Marshall GM; Li J; Vandesompele J; Mattick JS; Mestdagh P; Perini G; Hannan RD; Dinger ME; Liu T, 2018, 'Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2453
    Conference Abstracts | 2018
    Professor Michelle Haber
    Ziegler D; Tsoli M; Tyrell V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'EAPH-09. POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i67 - i67, http://dx.doi.org/10.1093/neuonc/noy059.178
    Conference Abstracts | 2018
    Professor Michelle Haber
    Khan A; Tsoli M; Yu D; Joshi S; Gamble L; Franshaw L; Haber M; Ziegler DS, 2018, 'Abstract 4800: Targeting the polyamine pathway as a novel therapeutic treatment against diffuse intrinsic pontine glioma', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, http://dx.doi.org/10.1158/1538-7445.am2018-4800
    Conference Abstracts | 2018
    Professor Michelle Haber
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i49 - i49, http://dx.doi.org/10.1093/neuonc/noy059.095
    Conference Posters | 2018
    Professor Michelle Haber
    Karsa M; Failes T; Arndt GM; Kees UR; Haber M; Norris MD; Sutton R; Lock RB; Somers K; Henderson MJ, 2018, 'PO-405 Repositioning existing drugs as novel therapeutics for high-risk paediatric leukaemia', Vol. 3, pp. A181 - A181, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.431
    Conference Abstracts | 2018
    Professor Michelle Haber
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Denver, CO, Vol. 20, pp. 49 - 49, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), Denver, CO, 30 June 2018 - 03 July 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Professor Michelle Haber
    Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
    Conference Papers | 2017
    Professor Michelle Haber
    Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'Abstract 2006: AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-2006
    Conference Papers | 2017
    Professor Michelle Haber
    Flynn AT; Vu A; Liu K; Scadden E; Attiyeh E; Norris M; Haber M; Hogarty M, 2017, 'Abstract 4883: Targeting tumor-amplifiedODC1with difluoromethylornithine (DFMO) inhibits global protein translation and has antitumor activity in neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-4883
    Conference Papers | 2017
    Professor Michelle Haber
    Gana CC; Hanssen K; Yu DM; Flemming C; Norris M; Haber M; Fletcher J, 2017, 'A modulator of multidrug resistance protein 1 selectively depletes glutathione and synergizes with L-buthionine sulfoximine to sensitize MRP1-expressing cancer cells to chemotherapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-4056
    Conference Papers | 2017
    Professor Michelle Haber
    Gao J; Somers K; Hannan KM; Fletcher JI; Liu B; Hannan RD; Pearson RB; Haber M; Norris MD; Henderson MJ, 2017, 'Abstract 1956: ABCE1 regulates the translational profile of neuroblastoma to drive tumor progression', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-1956
    Conference Papers | 2017
    Professor Michelle Haber
    Somers K; Middlemiss S; Biktasova A; Karsa M; Cheung L; Kosciolek A; Evans K; Mayoh C; Kees UR; Korotchkina L; Chernova OB; Lock RB; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2017, 'Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-1175
    Conference Abstracts | 2017
    Professor Michelle Haber
    Karsa M; Somers K; Mariana A; Failes T; Arndt GM; Kees UR; Haber M; Norris MD; Sutton R; Lock RB; Henderson MJ, 2017, 'REPOSITIONING EXISTING DRUGS AS NOVEL THERAPEUTICS: OXIDATIVE STRESS AS A TARGET FOR HIGH-RISK LEUKAEMIA IN CHILDREN', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, Madrid, SPAIN, Vol. 102, pp. 27 - 27, presented at 22nd Congress of the European-Hematology-Association, Madrid, SPAIN, 22 June 2017 - 25 June 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000404127001055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2016
    Professor Michelle Haber
    Xue C; Yu DM; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Russell A; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA, http://dx.doi.org/10.1158/1538-7445.am2016-2450
    Conference Papers | 2016
    Professor Michelle Haber
    Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Duong HTT; Boyer C; Flemming C; Yee EMH; Kumar N; Parmar A; Pascali G; Charil A; Haber M; Norris M; Kavallaris M, 2016, 'Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, New Orleans, LA, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), New Orleans, LA, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1340
    Conference Papers | 2016
    Professor Michelle Haber
    Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2016, 'Abstract 51: Molecular profiling of relapsed childhood cancer', in Other Topics, American Association for Cancer Research, presented at Abstracts: AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy; June 13-16, 2015; Salt Lake City, UT, http://dx.doi.org/10.1158/1557-3265.pmsclingen15-51
    Conference Abstracts | 2016
    Professor Michelle Haber
    Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'HG-20COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.4 - iii51, http://dx.doi.org/10.1093/neuonc/now073.17
    Conference Papers | 2016
    Professor Michelle Haber
    Koach J; Murray JE; McCarroll J; Milazzo G; Perini G; Haber M; Norris MD; Fletcher JI; Cheung BB; Marshall GM, 2016, 'Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S7 - S7, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000431649800017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Professor Michelle Haber
    Koach J; Liu B; Bell JL; Huettelmaier S; Liu T; Carter DR; Haber M; Norris MD; Fletcher J; Cheung BB; Marshall GM, 2015, 'PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-962
    Conference Abstracts | 2015
    Professor Michelle Haber
    Chudakova D; Somers K; Middlemiss S; Wen V; Kwek A; Liu B; Clifton M; Pan S; Cruikshank S; Scandlyn M; Failes T; Hoang W; Kees U; Chernova O; Gudkov AV; Haber M; Norris M; Henderson M, 2015, 'Selective and rapid killing of mixed lineage leukemia and CALM-AF10 leukemia by SM7, a novel small molecule identified by chemical library screening', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Fort Lauderdale, FL, Vol. 76, presented at AACR Special Conference on Advances in Pediatric Cancer Research - From Mechanisms and Models to Treatment and Survivorship, Fort Lauderdale, FL, 09 November 2015 - 12 November 2015, http://dx.doi.org/10.1158/1538-7445.PEDCA15-B23
    Conference Abstracts | 2015
    Professor Michelle Haber
    Tee AE; Liu P; Maag J; Song R; Li J; Cheung BB; Haber M; Norris MD; Marshall GM; Dinger M; Liu T, 2015, 'The long noncoding RNA MALAT1 promotes hypoxia-driven angiogenesis by upregulating pro-angiogenic gene expression in neuroblastoma cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-146
    Conference Papers | 2015
    Professor Michelle Haber
    Williams R; Russell A; Bongers A; Sagnella S; Fife C; Jessup W; DeFazio A; Chenevix-Trench G; Haber M; Norris M; Henderson M, 2015, 'Abstract 313: Examining the role of ABCA1 cholesterol transporter in ovarian cancer spheroids', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2015-313
    Conference Abstracts | 2015
    Professor Michelle Haber
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Henderson MJ; Middlemass S; Carter D; Tsoli M; Ehteda A; Simon S; Oberthuer A; Fischer M; Gurova K; Burkhart C; Purmal A; Lock RB; Ziegler D; Marshall GM; Gudkov AV; Norris MD, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1611
    Conference Papers | 2015
    Professor Michelle Haber
    O'Brien R; Maritz MF; Kong CF; Purgato S; Liu B; Yang C; Russell A; Murray J; Flemming C; Haber M; Perini G; Norris MD; Fletcher JI; Mackenzie KL, 2015, 'Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2015-488
    Conference Presentations | 2014
    Professor Michelle Haber
    Shahbazi J; Scarlett CJ; Norris M; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock R; Liu T, 2014, 'Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Vol. 74, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-5138
    Conference Papers | 2014
    Professor Michelle Haber
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, European Org Res & Treatment Canc, Barcelona, SPAIN, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, European Org Res & Treatment Canc, Barcelona, SPAIN, 18 November 2014 - 21 November 2014, http://dx.doi.org/10.1016/S0959-8049(14)70548-9
    Conference Papers | 2014
    Professor Michelle Haber
    Tsoli M; Vanniasinghe A; Luk P; Dilda P; Haber M; Hogg P; Ziegler D, 2014, 'TARGETING MITOCHONDRIA AND CELL METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Singapore, SINGAPORE, pp. 47 - 47, presented at 16th International Symposium on Pediatric Neuro-Oncology (ISPNO), Singapore, SINGAPORE, 28 June 2014 - 02 July 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337924200179&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Professor Michelle Haber
    Carter DR; Cheung BB; Liu T; Liu C; Norris MD; Haber M; Murray J; Gurova KV; Gudkov AV; Marshall GM, 2013, 'The facilitates chromatin transcription (FACT) protein complex promotes neuroblastoma tumor initiation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-5043
    Conference Papers | 2013
    Professor Michelle Haber
    Haber M; Murray J; Carnegie-Clark A; Webber H; Marshall GM; Gurova KV; Burkhart CA; Purmai A; Gudkov AV; Norris MD, 2013, 'Anticancer compound curaxin CBL0137, that simultaneously suppresses NF-kappa B and activates p53, is highly effective in two independent mouse models of neuroblastoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-2759
    Conference Papers | 2013
    Professor Michelle Haber
    Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3808
    Conference Papers | 2013
    Professor Michelle Haber
    Tsoli M; Luk P; Dilda P; Hogg P; Haber M; Ziegler D, 2013, 'TARGETING MITOCHONDRIA AND METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Fort Lauderdale, FL, pp. 21 - 21, presented at 2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, Fort Lauderdale, FL, 16 May 2013 - 17 May 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318570500078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Professor Michelle Haber
    Huynh T; Tivnan A; Munoz M; Cheung L; Vishvanath A; Flemming C; Watt F; Burkhart C; Gudkov A; Fletcher J; Henderson M; Norris M; Haber M, 2012, 'Abstract 1834: Targeting ABC transporters in cancer through small molecule inhibitors', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL, http://dx.doi.org/10.1158/1538-7445.am2012-1834
    Conference Papers | 2012
    Professor Michelle Haber
    Norris MD; Fletcher JI; Gherardi S; Murray J; Burkhart C; Russell A; Valli E; Oberthuer A; Ashton LJ; London WB; Marshall GM; Perini G; Haber M, 2012, 'GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-789
    Conference Abstracts | 2011
    Professor Michelle Haber
    Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; MacKenzie KL; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-3027
    Conference Papers | 2011
    Professor Michelle Haber
    Norris MD; Henderson MJ; Porro A; Munoz M; Iraci N; Xue C; Murray J; Flemming C; Fletcher J; Gherardi S; Kwek A; Russell A; London WB; Buxton AB; Ashton L; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Haber M, 2011, 'ABCC/MRP multidrug transporters contribute to neuroblastoma biology, pathogenesis and clinical outcome, independently of any role in cytotoxic drug efflux', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-954
    Conference Papers | 2011
    Professor Michelle Haber
    MacGregor S; Lu Y; Johnatty S; Beesley J; Chen XQ; Fridley B; Webb P; Gurney H; Harnett P; Haber M; Goode E; De Fazio A; Chenevix-Trench G, 2011, 'Abstract 4679: A multi-stage genome-wide association study on response to chemotherapy in ovarian cancer', in Epidemiology, American Association for Cancer Research, presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.am2011-4679
    Conference Papers | 2011
    Professor Michelle Haber
    Xue C; Cheung L; Norris MD; Haber M; Burkhart C; Fedtsova N; Gudkov A; Makarov SS, 2011, 'Abstract 617: Small molecule that simultaneously inhibits Myc oncoprotein and activates HIF1A', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.am2011-617
    Conference Papers | 2011
    Professor Michelle Haber
    Lau DT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'New evidence supports the potential use of methotrexate in children with MYCN-amplified neuroblastoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-LB-367
    Conference Papers | 2011
    Professor Michelle Haber
    Henderson MJ; Hedditch EL; Russell AJ; deFazio A; Emmanuel C; George J; Chenevix-Trench G; Bowtell D; Norris MD; Haber M, 2011, 'Abstract 1660: Cholesterol efflux transporter gene expression predicts clinical outcome in serous ovarian cancer', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.am2011-1660
    Conference Papers | 2010
    Professor Michelle Haber
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair T; Scarlett C; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Stossi F; Katzenellenbogen BS; Biankin AV; Perini G; Liu T, 2010, 'Abstract 4869: Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', in Cellular and Molecular Biology, American Association for Cancer Research, presented at Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am10-4869
    Conference Papers | 2010
    Professor Michelle Haber
    Lau DT; Murray J; Norris M; Marshall GM; Haber M; Ashton LJ, 2010, 'Abstract 888: Reduced folate carrier gene polymorphism (RFC 80G>A): Associations with clinical outcome in NMYC amplified neuroblastoma patients', in Epidemiology, American Association for Cancer Research, presented at Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am10-888
    Conference Papers | 2008
    Professor Michelle Haber
    Haber M; Cheng N; Smith J; Murray J; Hogarty MD; London WB; Marshall GM; Norris MD, 2008, 'Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2008-5832
    Conference Papers | 2008
    Professor Michelle Haber
    Bell JL; Cheung BB; D'Andreti C; Koach J; Raif A; Thomas WD; Norris M; Haber M; Kavallaris M; Marshall GM, 2008, 'The role of the estrogen-responsive B box protein (EBBP) in cancer cell cycle progression', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Lyon, FRANCE, pp. 95 - 95, presented at 20th Meeting of the European-Association-for-Cancer-Research, Lyon, FRANCE, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71542-8
    Conference Abstracts | 2008
    Professor Michelle Haber
    Sutton R; Venn NC; Kilo T; Bhadri V; Pozza LD; Marshall GM; Haber M; Norris MD; Shaw P, 2008, 'The value of monitoring for minimal residual disease post-transplant in children with acute lymphoblastic leukaemia', in British Journal of Haematology, Blackwell Publishing Ltd, Oxford, England, Vol. 141, pp. 102 - 102, presented at Abstracts of the British Society of Haematology 48th Annual Scientific Meeting, incorporating the 6th Bi-Annual I-BFM Leukaemia Symposium, Glasgow, SCOTLAND, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255032500279&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2007
    Professor Michelle Haber
    Norris MD; Smith J; Kwek A; Flemming C; Cohn SL; London WB; Buxton A; Marshall GM; Haber M, 2007, 'Expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3, and ABCC4/MRP4 are powerful predictors of clinical outcome in childhood neuroblastoma', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000455043702481&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Professor Michelle Haber
    Cheung BB; Bell J; Raif A; Yan J; Roediger B; Smith S; Lee M; Thomas WD; Kavallaris M; Norris M; Haber M; Liu H-L; Zajchowski D; Marshall GM, 2006, 'Characterization of a novel regulator of the retinoid signal: The estrogen-responsive B box protein.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454608804357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2006
    Professor Michelle Haber
    Choi S; Kwan E; Beesley A; Sutton R; Lock RB; Papa R; Marshall GM; Kees UR; Haber M; Norris MD, 2006, 'Relapse in children with acute lymphoblastic leukaemia is associated with selection of a pre-existing drug resistance subclone', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 81 - 81, http://dx.doi.org/10.1016/S1359-6349(06)70257-9
    Conference Papers | 2006
    Professor Michelle Haber
    Ashton LJ; Murray JE; Marshall GM; Haber M; Ashley DM; Norris MD, 2006, 'Polymorphisms of glutathione-S-transferase and N-acetyltransferase genes and response to treatment in childhood neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606202297&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Professor Michelle Haber
    Burkhart CA; Watt F; Pajic M; Murray J; Xue C; Flemming C; Smith J; Marshall GM; Haber M; Norris MD; Gudkov AV, 2006, 'Selective Sensitization of murine tumors to chemotherapy by a novel class of non-toxic small molecule inhibitors of MRP1', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606201252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Professor Michelle Haber
    Thomas WD; Keating J; Cheung B; Armatai P; Weiss W; Norris M; Haber M; Marshall GM, 2006, 'Neuroblastoma tumor initiation: MYCN mediated mechanisms of resistance to cell death', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606201380&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2003
    Professor Michelle Haber
    Laughton SJ; Ashton LJ; Kwan E; Norris MD; Haber M; Marshall GM, 2003, 'Early markers of the therapeutic index in children with acute lymphoblastic leukaemia predict outcome.', in BLOOD, AMER SOC HEMATOLOGY, SAN DIEGO, CALIFORNIA, pp. 879A - 879A, presented at 45th Annual Meeting of the American-Society-of-Hematology, SAN DIEGO, CALIFORNIA, 06 December 2003 - 09 December 2003, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186536703271&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Professor Michelle Haber
    Verrills N; Flemming C; Liu M; Ivery M; Norris MD; Haber M; Kavallaris M, 2002, 'Acquired beta-tubulin mutations affecting microtubule stability and drug binding', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 463A - 463A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102604&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2001
    Professor Michelle Haber
    Lock RB; Liem N; Tajbakhsh M; Milross CG; Xue CY; Haber M; Norris MD; Marshall GM; Rice AM, 2001, 'Novel biological characteristics and disparate vincristine responses of primary childhood acute lymphoblastic leukemia cells engrafted into non-obese diabetic/severe combined immunodeficient mice.', in BLOOD, AMER SOC HEMATOLOGY, pp. 309A - 310A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172134101312&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 1985
    Professor Michelle Haber
    STEWART BW; KAVALLARIS M; SMITH GJ; HABER M, 1985, 'MONITORING REPAIR AND REPLICATIVE-INDUCED STRUCTURAL-CHANGE IN CULTURES OF PROLIFERATING MAMMALIAN-CELLS', in MEDICAL AND PEDIATRIC ONCOLOGY, WILEY-LISS, Vol. 13, pp. 135 - 135, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AHS3500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Awards

Honours:

2007           Member of the Order of Australia (AM) for services to science in the field of research into childhood cancer, to scientific education and to the community

2010-12     President, Advances in Neuroblastoma Research Association.

2008           Degree of Doctor of Science, honoris causa, in recognition of eminent service to the community, University of New South Wales

2015           Inaugural Fellow, Australian Academy of Health and Medical Sciences

2020           Invited Speaker, American Association for Cancer Research, Presidential Select Symposium, San Diego, CA, USA

Awards:

2011           Winner - NSW Science and Engineering Award for Biomedical Sciences

2012           Winner - Cancer Institute NSW Premier’s Award for Excellence in Translational Cancer Research

2013           Finalist - NSW Health Jamie Callachor Eureka Prize for Medical Research Translation

2014           Winner - Best Translational Research Presentation, Advances in Neuroblastoma Research Congress, Cologne, Germany

2014           Winner - Cancer Institute NSW’s Premier’s Award for Outstanding Cancer Researcher of the Year

2015           Finalist - The Australian Innovation Challenge Award, for pioneering work in improving the survival rates of children with acute lymphoblastic leukaemia

2018           Finalist - CSIRO Eureka Prize for Leadership in Innovation and Science

Grants

  • 2020-2024   MRFF Emerging Priorities and Consumer Driven Research initiative EPCD000015) 'ZERO Childhood Cancer National Precision Medicine Program'
  • 2020-2023   Australian Cancer Research Foundation 'The ACRF Child Cancer Liquid Biopsy Program'
  • 2020-2023   Neuroblastoma Australia ‘MYC inhibitors to potentiate CART cell therapy
  • 2020-2023   Cancer Australia/ The Kids Cancer Project ‘Enhanced polyamine depletion as a novel therapy for aggressive cancers
  • 2019- 2021  Cancer Australia- 'Targeting the NAD pathway as a new therapeutic strategy for high-risk leukaemia in children'
  • 2019- 2023 APP1159004 NHMRC Partnerships Project- 'The economic impact of precision medicine in high risk and aggressive childhood cancer'
  • 2018-2022 Children’s Cancer Foundation- 'SIOPEN neuroblastoma clinical trials in Australia and New Zealand'
  • 2018-2021 Children’s Cancer Foundation- 'Leveraging the SIOPEN High risk 2.0 clinical trial for high-risk neuroblastoma to understand relapse, improve residual disease detection and develop pre-clinical testing models for high-risk neuroblastoma'
  • 2018 Cancer Australia/Medical Research Future Fund Australian Brain Cancer Mission- 'Zero Childhood Brain'

  • 2019 Tour de Cure Foundation - 'A personalised medicine approach to the treatment of acute myeloid leukaemia in children'

  • 2018 REG181200 – Cancer Institute NSW Research Equipment Grant- 'Australia’s first deformability cytometer – a novel tool for cancer mechanobiology and diagnosis'

  • 2018- 2020 APP1136278 – NHMRC Development Grant- 'Multidrug Resistance Protein 1 inhibitors to sensitise cancers to chemotherapy'

  • 2018- 2022 APP1132608 – NHMRC Program Grant- 'More effective therapeutic targeting of high risk childhood cancer: Neuroblastoma as a model'

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