Professor Murray David Norris
Director

Professor Murray David Norris

BSc Australian National University (1975)
MAppSci NSW Institute of Technology (1984)
PhD University of New South Wales (1988)

medicine-health
Childhood Cancer Research

Professor Murray Norris obtained his PhD at UNSW in 1988 and subsequently undertook Postdoctoral positions at the Prince of Wales Children’s Hospital (Randwick) and then at the University of Illinois, Chicago, USA. In 2000, he was appointed as the Deputy Director of the Children’s Cancer Institute, where he is the Co-Head of the Molecular Targets and Cancer Therapeutics Theme, and also heads the Molecular Oncology Group. From 2010-19, Professor Norris was Director of the ACRF Drug Discovery Centre, where he pioneered the development of cell-based high-throughput screening methodology of small-molecule libraries for child cancer and developed highly potent inhibitors of drug resistance proteins (MRPs) as well as licensing of MRP4 inhibitors to the global biotech company, Abcam Plc. Since 2015, he has been the Director of the UNSW Centre for Childhood Cancer Research.

His research interests focus on utilising new molecular genetic technologies to improve the diagnosis, risk classification and treatment of childhood cancer, and he has been responsible for developing and implementing unique technology enabling the early prediction of relapse in children with acute lymphoblastic leukaemia. This technology has become a powerful tool for the early detection of relapse in children with leukaemia and has affected a major change in the clinical management of patients with this disease. Professor Norris has earned an international reputation as an expert in neuroblastoma research, particularly with regards to the molecular analysis of genes and their relationship with clinical variables. He has spent over 30 years investigating childhood cancers at the molecular level, and has undertaken extensive research into the characterisation of genes involved in mediating resistance to chemotherapeutic drugs in paediatric leukaemia and neuroblastoma. His research is increasingly focused on understanding the regulation of the MYCN oncogene and its downstream targets, with the goal of developing molecular targeted therapies, and his findings in this area are being translated into a number of early phase clinical trials.

Phone
02 7209 6709
Location
Lowy Cancer Research Centre C25 Gate 9, UNSW High Street RANDWICK NSW 2031

Publications

  • Book Chapters | 2014
    Professor Murray David Norris
    Fletcher J; Roundhill E; Haber M; Norris M, 2014, 'Clinical relevance of multidrug-resistance-proteins (MRPs) for anticancer drug resistance and prognosis', in Efferth T; Bonavida B (ed.), Resistancce to Targeted Anti-Cancer Therapeutics, Springer Press., pp. 27 - 52
    Book Chapters | 2013
    Professor Murray David Norris
    Cheung L; Murray JE; Norris MD; Haber M, 2013, 'Oncogene and Cancer - From Bench to Clinic', in Siregar YE; norris (ed.), Oncogene and Cancer - From Bench to Clinic, Inst za onkologiju i radiol, pp. 437 - 454, http://dx.doi.org/10.5772/54813
    Book Chapters | 2013
    Professor Murray David Norris
    Norris MD; Burkhart CA; Haber M; Gudkov AV; Nikiforov MA, 2013, 'Cell-Based Methods for the Identification of MYC-Inhibitory Small Molecules', in Soucek L; Sodir NM (ed.), The Myc Gene, edn. Methods in Molecular Biology, Humana Press Inc, pp. 255 - 264, http://dx.doi.org/10.1007/978-1-62703-429-6_18
    Book Chapters | 2012
    Professor Murray David Norris
    Fletcher JI; Haber M; Henderson M; Norris MD, 2012, 'Targeting Multidrug Resistance in Neuroblastoma', in Hayat MA (ed.), Pediatric Cancer Volume 1 Diagnosis, Therapy and Prognosis: Neuroblastoma, edn. Pediatric Cancer-Diagnosis Therapy and Prognosis, Springer, New York, USA, pp. 115 - 123, http://dx.doi.org/10.1007/978-94-007-2418-1_11
    Book Chapters | 2012
    Professor Murray David Norris
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2012, 'The Myc Gene: Methods and Protocols: Myc inhibitory molecules', in Methods in Molecular Biology, edn. Original, Humana Press
    Book Chapters | 2012
    Professor Murray David Norris
    Xue C; Gudkov A; Haber M; Norris MD, 2012, 'Small molecule drugs and targeted therapies for neuroblastoma', in Shimada H (ed.), Neuroblastoma - Present and Future, edn. First, In Tech, Croatia, pp. 299 - 324, http://www.amazon.com/Neuroblastoma-Present-and-Future-ebook/dp/B00CBWQI92/ref=sr_1_1?ie=UTF8&qid=1366940364&sr=8-1&keywords=neuroblastoma+-+present+and+future#reader_B00CBWQI92
    Book Chapters | 2000
    Professor Murray David Norris
    Cheung NC; Norris MD, 2000, 'Detection of Microscopic Residual Tumors in Bone Marrow', in Neuroblastoma, edn. Original, Elsevier Science BV, Amsterdam, pp. 333 - 340
  • Journal articles | 2021
    Professor Murray David Norris
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Hayden E; Rouaen J; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Kankean A; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov A; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION IN DIPG', NEURO-ONCOLOGY, vol. 23, pp. 18 - 19, http://dx.doi.org/10.1093/neuonc/noab090.075
    Journal articles | 2021
    Professor Murray David Norris
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Joshi S; Rouaen JRC; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Tolhurst O; Kankean A; Hayden E; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov AV; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG', Cell Reports, vol. 35, pp. 108994 - 108994, http://dx.doi.org/10.1016/j.celrep.2021.108994
    Journal articles | 2021
    Professor Murray David Norris
    Xiao L; Somers K; Murray J; Pandher R; Karsa M; Ronca E; Bongers A; Terry R; Ehteda A; Gamble LD; Issaeva N; Leonova KI; O'Connor A; Mayoh C; Venkat P; Quek H; Brand J; Kusuma FK; Pettitt JA; Mosmann E; Kearns A; Eden G; Alfred S; Allan S; Zhai L; Kamili A; Gifford AJ; Carter DR; Henderson MJ; Fletcher JI; Marshall G; Johnstone RW; Cesare AJ; Ziegler DS; Gudkov AV; Gurova KV; Norris MD; Haber M, 2021, 'Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.', Clin Cancer Res, vol. 27, pp. 4338 - 4352, http://dx.doi.org/10.1158/1078-0432.CCR-20-2357
    Journal articles | 2021
    Professor Murray David Norris
    Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, vol. 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z
    Journal articles | 2021
    Professor Murray David Norris
    Karsa M; Kosciolek A; Bongers A; Mariana A; Failes T; Gifford AJ; Kees UR; Cheung LC; Kotecha RS; Arndt GM; Haber M; Norris MD; Sutton R; Lock RB; Henderson MJ; Somers K, 2021, 'Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin', British Journal of Cancer, vol. 125, pp. 55 - 64, http://dx.doi.org/10.1038/s41416-021-01332-x
    Journal articles | 2021
    Professor Murray David Norris
    Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, vol. 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906
    Journal articles | 2021
    Professor Murray David Norris
    Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, vol. 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044
    Journal articles | 2021
    Professor Murray David Norris
    Xiao L; Yeung H; Haber M; Norris MD; Somers K, 2021, 'Immunometabolism: A ‘Hot’ Switch for ‘Cold’ Pediatric Solid Tumors', Trends in Cancer, vol. 7, pp. 751 - 777, http://dx.doi.org/10.1016/j.trecan.2021.05.002
    Journal articles | 2021
    Professor Murray David Norris
    Cheung BB; Kleynhans A; Mittra R; Kim PY; Holien JK; Nagy Z; Ciampa OC; Seneviratne JA; Mayoh C; Raipuria M; Gadde S; Massudi H; Wong IPL; Tan O; Gong A; Suryano A; Diakiw SM; Liu B; Arndt GM; Liu T; Kumar N; Sangfelt O; Zhu S; Norris MD; Haber M; Carter DR; Parker MW; Marshall GM, 2021, 'A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma', Oncogene, vol. 40, pp. 2367 - 2381, http://dx.doi.org/10.1038/s41388-021-01712-w
    Journal articles | 2021
    Professor Murray David Norris
    Bӧhm JW; Sia KCS; Jones C; Evans K; Mariana A; Pang I; Failes T; Zhong L; Mayoh C; Landman R; Collins R; Erickson SW; Arndt G; Raftery MJ; Wilkins MR; Norris MD; Haber M; Marshall GM; Lock RB, 2021, 'Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia', Leukemia, http://dx.doi.org/10.1038/s41375-021-01248-8
    Journal articles | 2021
    Professor Murray David Norris
    Gamble LD; Purgato S; Henderson MJ; Di Giacomo S; Russell AJ; Pigini P; Murray J; Valli E; Milazzo G; Giorgi FM; Cowley M; Ashton LJ; Bhalshankar J; Schleiermacher G; Rihani A; Van Maerken T; Vandesompele J; Speleman F; Versteeg R; Koster J; Eggert A; Noguera R; Stallings RL; Tonini GP; Fong K; Vaksman Z; Diskin SJ; Maris JM; London WB; Marshall GM; Ziegler DS; Hogarty MD; Perini G; Norris MD; Haber M, 2021, 'A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma', Cancers, vol. 13, http://dx.doi.org/10.3390/cancers13081807
    Journal articles | 2021
    Professor Murray David Norris
    Khan A; Gamble L; Upton D; Yu D; Pandher R; Mayoh C; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', NEURO-ONCOLOGY, vol. 23, pp. 40 - 41, http://dx.doi.org/10.1093/neuonc/noab090.163
    Journal articles | 2021
    Professor Murray David Norris
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2021, 'Cell-based methods for the identification of Myc-inhibitory small molecules', Methods Mol Biol, vol. 2318, pp. 337 - 346, http://dx.doi.org/10.1007/978-1-0716-1476-1_19
    Journal articles | 2020
    Professor Murray David Norris
    Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, vol. 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014
    Journal articles | 2020
    Professor Murray David Norris
    Korotchkina L; Kazyulkin D; Komarov PG; Polinsky A; Andrianova EL; Joshi S; Gupta M; Vujcic S; Kononov E; Toshkov I; Tian Y; Krasnov P; Chernov MV; Veith J; Antoch MP; Middlemiss S; Somers K; Lock RB; Norris MD; Henderson MJ; Haber M; Chernova OB; Gudkov AV, 2020, 'OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis', Leukemia, vol. 34, pp. 1828 - 1839, http://dx.doi.org/10.1038/s41375-019-0692-5
    Journal articles | 2020
    Professor Murray David Norris
    Somers K; Evans K; Cheung L; Karsa M; Pritchard T; Kosciolek A; Bongers A; El-Ayoubi A; Forgham H; Middlemiss S; Mayoh C; Jones L; Gupta M; Kees UR; Chernova O; Korotchkina L; Gudkov AV; Erickson SW; Teicher B; Smith MA; Norris MD; Haber M; Lock RB; Henderson MJ, 2020, 'Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia', Leukemia, vol. 34, pp. 1524 - 1539, http://dx.doi.org/10.1038/s41375-019-0683-6
    Journal articles | 2020
    Professor Murray David Norris
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Professor Murray David Norris
    Huynh T; Murray J; Flemming CL; Kamili A; Hofmann U; Cheung L; Roundhill EA; Yu DMT; Webber HT; Schwab M; Henderson MJ; Haber M; Norris MD; Fletcher JI, 2020, 'CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth', Biochemical Pharmacology, vol. 172, http://dx.doi.org/10.1016/j.bcp.2019.113770
    Journal articles | 2020
    Professor Murray David Norris
    Khan A; Valli E; Lam H; Scott DA; Murray J; Hanssen KM; Eden G; Gamble LD; Pandher R; Flemming CL; Allan S; Osterman AL; Haber M; Norris MD; Fletcher JI; Yu DMT, 2020, 'Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition', Oncogene, vol. 39, pp. 3555 - 3570, http://dx.doi.org/10.1038/s41388-020-1235-2
    Journal articles | 2020
    Professor Murray David Norris
    Jung M; Gao J; Cheung L; Bongers A; Somers K; Clifton M; Ramsay EE; Russell AJ; Valli E; Gifford AJ; George J; Kennedy CJ; Wakefield MJ; Topp M; Ho GY; Scott CL; Bowtell DD; deFazio A; Norris MD; Haber M; Henderson MJ, 2020, 'ABCC4/MRP4 contributes to the aggressiveness of Myc-associated epithelial ovarian cancer', International Journal of Cancer, vol. 147, pp. 2225 - 2238, http://dx.doi.org/10.1002/ijc.33005
    Journal articles | 2020
    Professor Murray David Norris
    Gao J; Jung MS; Mayoh C; Venkat P; Hannan KM; Fletcher JI; Kamili A; Gifford AJ; Kusnadi EP; Pearson RB; Hannan RD; Haber M; Norris MD; Somers K; Henderson MJ, 2020, 'Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression', Cancer Research, vol. 80, pp. 3706 - 3718, http://dx.doi.org/10.1158/0008-5472.CAN-19-3914
    Journal articles | 2020
    Professor Murray David Norris
    Sia KCS; Zhong L; Mayoh C; Norris MD; Haber M; Marshall GM; Raftery MJ; Lock RB, 2020, 'Targeting TSLP-induced tyrosine kinase signaling pathways in CRLF2-Rearranged Ph-like ALL', Molecular Cancer Research, vol. 18, pp. 1767 - 1776, http://dx.doi.org/10.1158/1541-7786.MCR-19-1098
    Journal articles | 2020
    Professor Murray David Norris
    Kamili A; Gifford AJ; Li N; Mayoh C; Chow S-O; Failes TW; Eden GL; Cadiz R; Xie J; Lukeis RE; Norris MD; Haber M; McCowage GB; Arndt GM; Trahair TN; Fletcher JI, 2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer, http://dx.doi.org/10.1038/s41416-019-0682-4
    Journal articles | 2020
    Professor Murray David Norris
    Ferrucci F; Ciaccio R; Monticelli S; Pigini P; Di Giacomo S; Purgato S; Erriquez D; Bernardoni R; Norris MD; Haber M; Milazzo G; Perini G, 2020, 'Corrigendum to: “MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma” [Biochim. Biophys. Acta, Gene Regul. Mech. 1861 (2018) 235–245] (BBA - Gene Regulatory Mechanisms (2018) 1861(3) (235–245), (S1874939917302894), (10.1016/j.bbagrm.2018.01.007))', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1863, http://dx.doi.org/10.1016/j.bbagrm.2020.194645
    Journal articles | 2019
    Professor Murray David Norris
    Dorstyn L; Hackett-Jones E; Nikolic A; Norris MD; Lim Y; Toubia J; Haber M; Kumar S, 2019, 'Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling', Cell Death and Disease, vol. 10, http://dx.doi.org/10.1038/s41419-018-1296-0
    Journal articles | 2019
    Professor Murray David Norris
    Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, vol. 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
    Journal articles | 2019
    Professor Murray David Norris
    Liu PY; Tee AE; Milazzo G; Hannan KM; Maag J; Mondal S; Atmadibrata B; Bartonicek N; Peng H; Ho N; Mayoh C; Ciaccio R; Sun Y; Henderson MJ; Gao J; Everaert C; Hulme AJ; Wong M; Lan Q; Cheung BB; Shi L; Wang JY; Simon T; Fischer M; Zhang XD; Marshall GM; Norris MD; Haber M; Vandesompele J; Li J; Mestdagh P; Hannan RD; Dinger ME; Perini G; Liu T, 2019, 'The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35', Nature Communications, vol. 10, pp. 5026, http://dx.doi.org/10.1038/s41467-019-12971-3
    Journal articles | 2019
    Professor Murray David Norris
    Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410, http://dx.doi.org/10.1038/s41375-018-0354-z
    Journal articles | 2019
    Professor Murray David Norris
    Somers K; Kosciolek A; Bongers A; El-Ayoubi A; Karsa M; Mayoh C; Wadham C; Middlemiss S; Neznanov N; Kees UR; Lock RB; Gudkov A; Sutton R; Gurova K; Haber M; Norris MD; Henderson MJ, 2019, 'Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia', International Journal of Cancer, http://dx.doi.org/10.1002/ijc.32582
    Journal articles | 2019
    Professor Murray David Norris
    Koach J; Holien JK; Massudi H; Carter DR; Ciampa OC; Herath M; Lim T; Seneviratne JA; Milazzo G; Murray JE; McCarroll JA; Liu B; Mayoh C; Keenan B; Stevenson BW; Gorman MA; Bell JL; Doughty L; Hüttelmaier S; Oberthuer A; Fischer M; Gifford AJ; Liu T; Zhang X; Zhu S; Gustafson WC; Haber M; Norris MD; Fletcher JI; Perini G; Parker MW; Cheung BB; Marshall GM, 2019, 'Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface', Cancer Research, vol. 79, pp. 5652 - 5667, http://dx.doi.org/10.1158/0008-5472.CAN-19-1112
    Journal articles | 2019
    Professor Murray David Norris
    Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, vol. 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
    Journal articles | 2019
    Professor Murray David Norris
    Franshaw L; Tsoli M; Byrne J; Mayoh C; Sivarajasingam S; Norris M; Marshall GM; Ziegler DS, 2019, 'Predictors of Success of Phase II Pediatric Oncology Clinical Trials', Oncologist, vol. 24, pp. e765 - e774, http://dx.doi.org/10.1634/theoncologist.2017-0666
    Journal articles | 2019
    Professor Murray David Norris
    Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, vol. 10, pp. 3319, http://dx.doi.org/10.1038/s41467-019-11132-w
    Journal articles | 2019
    Professor Murray David Norris
    Gana CC; Hanssen KM; Yu DMT; Flemming CL; Wheatley MS; Conseil G; Cole SPC; Norris MD; Haber M; Fletcher JI, 2019, 'MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells', Biochemical Pharmacology, vol. 168, pp. 237 - 248, http://dx.doi.org/10.1016/j.bcp.2019.07.009
    Journal articles | 2019
    Professor Murray David Norris
    Gonzales-Aloy E; Connerty P; Salik B; Liu B; Woo AJ; Haber M; Norris MD; Wang J; Wang JY, 2019, 'MiR-101 suppresses the development of MLL-rearranged acute myeloid leukemia', Haematologica, vol. 104, pp. e296 - e299, http://dx.doi.org/10.3324/haematol.2018.209437
    Journal articles | 2019
    Professor Murray David Norris
    Fultang L; Gamble LD; Gneo L; Berry AM; Egan SA; De Bie F; Yogev O; Eden GL; Booth S; Brownhill S; Vardon A; McConville CM; Cheng PN; Norris MD; Etchevers HC; Murray J; Ziegler DS; Chesler L; Schmidt R; Burchill SA; Haber M; De Santo C; Mussai F, 2019, 'Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma', Cancer Research, vol. 79, pp. 611 - 624, http://dx.doi.org/10.1158/0008-5472.CAN-18-2139
    Journal articles | 2018
    Professor Murray David Norris
    Ooi CY; Carter DR; Liu B; Mayoh C; Beckers A; Lalwani A; Nagy Z; De Brouwer S; Decaesteker B; Hung TT; Norris MD; Haber M; Liu T; De Preter K; Speleman F; Cheung BB; Marshall GM, 2018, 'Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN', Cancer Research, vol. 78, pp. 3122 - 3134, http://dx.doi.org/10.1158/0008-5472.CAN-17-3034
    Journal articles | 2018
    Professor Murray David Norris
    Ferrucci F; Ciaccio R; Monticelli S; Pigini P; di Giacomo S; Purgato S; Erriquez D; Bernardoni R; Norris M; Haber M; Milazzo G; Perini G, 2018, 'MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1861, pp. 235 - 245, http://dx.doi.org/10.1016/j.bbagrm.2018.01.007
    Journal articles | 2018
    Professor Murray David Norris
    Jung M; Russell A; Kennedy C; Gifford A, 2018, 'Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer', JNCI: Cancer Spectrum, vol. 2, http://dx.doi.org/10.1093/jncics/pky047
    Journal articles | 2018
    Professor Murray David Norris
    Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, vol. 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
    Journal articles | 2018
    Professor Murray David Norris
    Sutton R; Venn NC; Law T; Boer JM; Trahair TN; Ng A; Den Boer ML; Dissanayake A; Giles JE; Dalzell P; Mayoh C; Barbaric D; Revesz T; Alvaro F; Pieters R; Haber M; Norris MD; Schrappe M; Dalla Pozza L; Marshall GM, 2018, 'A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children', British Journal of Haematology, vol. 180, pp. 550 - 562, http://dx.doi.org/10.1111/bjh.15056
    Journal articles | 2018
    Professor Murray David Norris
    Marachelian A; Hogarty MD; Flynn A; Liu K; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer C; Norris M; Haber M; Groshen SG; Ziegler DS; Matthay KK, 2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', Journal of Clinical Oncology, vol. 36, pp. 10558 - 10558, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.10558
    Journal articles | 2018
    Professor Murray David Norris
    Somers K; Evans K; Cheung L; Korotchkina L; Chernova O; Gudkov A; Norris M; Haber M; Lock R; Henderson M, 2018, 'PO-028 Effective targeting of NAD+biosynthesis in patient-derived xenograft models of high-risk paediatric acute lymphoblastic leukaemia', ESMO Open, vol. 3, pp. A238 - A238, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.563
    Journal articles | 2017
    Professor Murray David Norris
    Heatley SL; Sadras T; Kok CH; Nievergall E; Quek K; Dang P; McClure B; Venn N; Moore S; Suttle J; Law T; Ng A; Muskovic W; Norris MD; Revesz T; Osborn M; Moore AS; Suppiah R; Fraser C; Alvaro F; Hughes TP; Mullighan CG; Marshall GM; Dalla Pozza L; Yeung DT; Sutton R; White DL, 2017, 'High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment', Haematologica, vol. 102, pp. e490 - e493, http://dx.doi.org/10.3324/haematol.2016.162925
    Journal articles | 2017
    Professor Murray David Norris
    Jung MS; Russell AJ; Liu B; George J; Liu PY; Liu T; DeFazio A; Bowtell DDL; Oberthuer A; London WB; Fletcher JI; Haber M; Norris MD; Henderson MJ, 2017, 'A Myc activity signature predicts poor clinical outcomes in Myc-associated cancers', Cancer Research, vol. 77, pp. 971 - 981, http://dx.doi.org/10.1158/0008-5472.CAN-15-2906
    Journal articles | 2017
    Professor Murray David Norris
    Murray J; Valli E; Yu DMT; Truong AM; Gifford AJ; Eden GL; Gamble LD; Hanssen KM; Flemming CL; Tan A; Tivnan A; Allan S; Saletta F; Cheung L; Ruhle M; Schuetz JD; Henderson MJ; Byrne JA; Norris MD; Haber M; Fletcher JI, 2017, 'Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo', European Journal of Cancer, vol. 83, pp. 132 - 141, http://dx.doi.org/10.1016/j.ejca.2017.06.024
    Journal articles | 2016
    Professor Murray David Norris
    Xue C; Yu DMT; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Valli E; Russell AJ; London WB; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4', Oncotarget, vol. 7, pp. 54937 - 54951, http://dx.doi.org/10.18632/oncotarget.10709
    Journal articles | 2016
    Professor Murray David Norris
    Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, vol. 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539
    Journal articles | 2016
    Professor Murray David Norris
    Lynch JR; Yi H; Casolari DA; Voli F; Gonzales-Aloy E; Fung TK; Liu B; Brown A; Liu T; Haber M; Norris MD; Lewis ID; So CWE; D'Andrea RJ; Wang JY, 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, vol. 30, pp. 1745 - 1748, http://dx.doi.org/10.1038/leu.2016.24
    Journal articles | 2016
    Professor Murray David Norris
    Tee AE; Liu B; Song R; Li J; Pasquier E; Cheung BB; Jiang C; Marshall GM; Haber M; Norris MD; Fletcher JI; Dinger ME; Liu T, 2016, 'The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression', Oncotarget, vol. 7, pp. 8663 - 8675, http://dx.doi.org/10.18632/oncotarget.6675
    Journal articles | 2016
    Professor Murray David Norris
    Fletcher JI; Williams RT; Henderson MJ; Norris MD; Haber M, 2016, 'ABC transporters as mediators of drug resistance and contributors to cancer cell biology', Drug Resistance Updates, vol. 26, pp. 1 - 9, http://dx.doi.org/10.1016/j.drup.2016.03.001
    Journal articles | 2016
    Professor Murray David Norris
    French JD; Johnatty SE; Lu Y; Beesley J; Gao B; Kalimutho M; Henderson MJ; Russell AJ; Kar S; Chen X; Hillman KM; Kaufmann S; Sivakumaran H; O'Reilly M; Wang C; Korbie DJ; Lambrechts D; Despierre E; Van Nieuwenhuysen E; Lambrechts S; Vergote I; Karlan B; Lester J; Orsulic S; Walsh C; Fasching PA; Beckmann MW; Ekici AB; Hein A; Matsuo K; Hosono S; Pisterer J; Hillemanns P; Nakanishi T; Yatabe Y; Goodman MT; Lurie G; Matsuno RK; Thompson PJ; Pejovic T; Bean Y; Heitz F; Harter P; Du Bois A; Schwaab I; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Lundvall L; Engelholm SA; Brown B; Flanagan JM; Metcalf MD; Siddiqui N; Sellers T; Fridley B; Cunningham J; Schildkraut JM; Iversen E; Weber RP; Brennan D; Berchuck A; Pharoah P; Harnett P; Norris MD; Haber M; Goode EL; Lee JS; Khanna KK; Meyer KB; Chenevix-Trench G; DeFazio A; Edwards SL; MacGregor S, 2016, 'Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer', Oncotarget, vol. 7, pp. 6353 - 6368, http://dx.doi.org/10.18632/oncotarget.7047
    Journal articles | 2016
    Professor Murray David Norris
    Somers K; Chudakova DA; Middlemiss SMC; Wen VW; Clifton M; Kwek A; Liu B; Mayoh C; Bongers A; Karsa M; Pan S; Cruikshank S; Scandlyn M; Hoang W; Imamura T; Kees UR; Gudkov AV; Chernova OB; Haber M; Norris MD; Henderson MJ, 2016, 'CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements', Oncotarget, vol. 7, pp. 46067 - 46087, http://dx.doi.org/10.18632/oncotarget.10022
    Journal articles | 2016
    Professor Murray David Norris
    Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, vol. 374, pp. 315 - 323, http://dx.doi.org/10.1016/j.canlet.2016.02.021
    Journal articles | 2016
    Professor Murray David Norris
    Carter DR; Sutton SK; Pajic M; Murray J; Sekyere EO; Fletcher J; Beckers A; De Preter K; Speleman F; George RE; Haber M; Norris MD; Cheung BB; Marshall GM, 2016, 'Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis', Molecular Oncology, vol. 10, pp. 866 - 878, http://dx.doi.org/10.1016/j.molonc.2016.02.004
    Journal articles | 2016
    Professor Murray David Norris
    Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640
    Journal articles | 2016
    Professor Murray David Norris
    Koach J; Murray JE; McCarroll J; Milazzo G; Perini G; Haber M; Norris MD; Fletcher JI; Cheung BB; Marshall GM, 2016, 'Proffered Paper: Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', European Journal of Cancer, vol. 61, pp. S7 - S7, http://dx.doi.org/10.1016/s0959-8049(16)61016-x
    Journal articles | 2016
    Professor Murray David Norris
    Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, vol. 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201
    Journal articles | 2016
    Professor Murray David Norris
    O'Brien R; Tran SL; Maritz MF; Liu B; Kong CF; Purgato S; Yang C; Murray J; Russell AJ; Flemming CL; von Jonquieres G; Pickett HA; London WB; Haber M; Gunaratne PH; Norris MD; Perini G; Fletcher JI; MacKenzie KL, 2016, 'MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin', Cancer Research, vol. 76, pp. 3604 - 3617, http://dx.doi.org/10.1158/0008-5472.CAN-15-0879
    Journal articles | 2016
    Professor Murray David Norris
    Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, vol. 69, pp. S63 - S64, http://dx.doi.org/10.1016/s0959-8049(16)32778-2
    Journal articles | 2015
    Professor Murray David Norris
    Bassiri H; Benavides A; Haber M; Gilmour SK; Norris MD; Hogarty MD, 2015, 'Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma', TRANSLATIONAL PEDIATRICS, vol. 4, pp. 226 - 238, http://dx.doi.org/10.3978/j.issn.2224-4336.2015.04.06
    Journal articles | 2015
    Professor Murray David Norris
    Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, vol. 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005
    Journal articles | 2015
    Professor Murray David Norris
    Milne E; Greenop KR; Scott RJ; Haber M; Norris MD; Attia J; Jamieson SE; Miller M; Bower C; Bailey HD; Dawson S; McCowage GB; De Klerk NH; Van Bockxmeer FM; Armstrong BK, 2015, 'Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia', Cancer Epidemiology Biomarkers and Prevention, vol. 24, pp. 48 - 56, http://dx.doi.org/10.1158/1055-9965.EPI-14-0680
    Journal articles | 2015
    Professor Murray David Norris
    Yu DMT; Huynh T; Truong AM; Haber M; Norris MD, 2015, 'ABC Transporters and Neuroblastoma', Advances in Cancer Research, vol. 125, pp. 139 - 170, http://dx.doi.org/10.1016/bs.acr.2014.10.005
    Journal articles | 2015
    Professor Murray David Norris
    Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.aab1803
    Journal articles | 2015
    Professor Murray David Norris
    Sutton R; Shaw PJ; Venn NC; Law T; Dissanayake A; Kilo T; Haber M; Norris MD; Fraser C; Alvaro F; Revesz T; Trahair TN; Dalla-Pozza L; Marshall GM; O'Brien TA, 2015, 'Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia', British Journal of Haematology, vol. 168, pp. 395 - 404, http://dx.doi.org/10.1111/bjh.13142
    Journal articles | 2015
    Professor Murray David Norris
    Lau DT; Flemming CL; Gherardi S; Perini G; Oberthuer A; Fischer M; Juraeva D; Brors B; Xue C; Norris MD; Marshall GM; Haber M; Fletcher JI; Ashton LJ, 2015, 'MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma', Oncotarget, vol. 6, pp. 15510 - 15523, http://dx.doi.org/10.18632/oncotarget.3732
    Journal articles | 2015
    Professor Murray David Norris
    Greenop KR; Scott RJ; Attia J; Bower C; De Klerk NH; Norris MD; Haber M; Jamieson SE; Van Bockxmeer FM; Gottardo NG; Ashton LJ; Armstrong BK; Milne E, 2015, 'Folate pathway gene polymorphisms and risk of childhood brain tumors: Results from an Australian case-control study', Cancer Epidemiology Biomarkers and Prevention, vol. 24, pp. 931 - 937, http://dx.doi.org/10.1158/1055-9965.EPI-14-1248
    Journal articles | 2014
    Professor Murray David Norris
    Dietrich PA; Yang C; Leung HHL; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY, 2014, 'GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis', Blood, vol. 124, pp. 3284 - 3294, http://dx.doi.org/10.1182/blood-2013-10-532523
    Journal articles | 2014
    Professor Murray David Norris
    Dorstyn L; Puccini J; Nikolic A; Shalini S; Wilson CH; Norris MD; Haber M; Kumar S, 2014, 'An unexpected role for caspase-2 in neuroblastoma', Cell Death and Disease, vol. 5, http://dx.doi.org/10.1038/cddis.2014.342
    Journal articles | 2014
    Professor Murray David Norris
    Shahbazi J; Scarlett CJ; Norris MD; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock RB; Liu T, 2014, 'Histone Deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Oncotarget, vol. 5, pp. 4257 - 4268, http://dx.doi.org/10.18632/oncotarget.1991
    Journal articles | 2014
    Professor Murray David Norris
    Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, vol. 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003
    Journal articles | 2014
    Professor Murray David Norris
    Tee EL; Ling D; Nelson C; Atmadibrata B; Dinger M; XU N; Mizukami T; Liu PY; Liu B; Cheung B; Pasquier E; Haber M; Norris MD; Suzuki T; Marshall GM; Liu T, 2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1', Oncotarget, vol. 5, pp. 1793 - 1804, http://dx.doi.org/10.18632/oncotarget.1785
    Journal articles | 2014
    Professor Murray David Norris
    Hedditch EL; Gao B; Russell AJ; Lu Y; Emmanuel C; Beesley J; Johnatty SE; Chen X; Harnett P; George J; Williams RT; Flemming C; Lambrechts D; Despierre E; Lambrechts S; Vergote I; Karlan B; Lester J; Orsulic S; Walsh C; Fasching P; Beckmann MW; Ekici AB; Hein A; Matsuo K; Hosono S; Nakanishi T; Yatabe Y; Pejovic T; Bean Y; Heitz F; Harter P; Du Bois A; Schwaab I; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Lundvall L; Engelholm SA; Brown B; Flanagan J; Metcalf MD; Siddiqui N; Sellers T; Fridley B; Cunningham J; Schildkraut J; Iversen E; Weber RP; Berchuck A; Goode E; Bowtell DD; Chenevix-Trench G; Defazio A; Norris MD; Macgregor S; Haber M; Henderson MJ, 2014, 'ABCA transporter gene expression and poor outcome in epithelial ovarian cancer', Journal of the National Cancer Institute, vol. 106, http://dx.doi.org/10.1093/jnci/dju149
    Journal articles | 2014
    Professor Murray David Norris
    Gao B; Russell A; Beesley J; Chen XQ; Healey S; Henderson M; Wong M; Emmanuel C; Galletta L; Johnatty SE; Bowtell D; Haber M; Norris M; Harnett P; Chenevix-Trench G; Balleine RL; Defazio A; Gertig D; Green A; Webb P; Hung J; Moore S; Traficante N; Fereday S; Harrap K; Sadkowsky T; Pandeya N; Stuart-Harris R; Kirsten F; Rutovitz J; Clingan P; Glasgow A; Proietto A; Braye S; Otton G; Shannon J; Bonaventura T; Stewart J; Begbie S; Friedlander M; Bell D; Baron-Hay S; Ferrier A; Gard G; Nevell D; Pavlakis N; Valmadre S; Young B; Camaris C; Crouch R; Edwards L; Hacker N; Marsden D; Robertson G; Beale P; Beith J; Carter J; Dalrymple C; Hamilton A; Houghton R; Russell P; Links M; Grygiel J; Hill J; Brand A; Byth K; Jaworski R; Sharma R; Achen A; Wain G; Ward B; Papadimos D; Crandon A; Cummings M; Horwood K; Obermair A; Perrin L; Wyld D; Nicklin J; Davy M; Oehler MK; Hall C; Dodd T; Healy T; Pittman K; Henderson D; Miller J; Pierdes J; Blomfield P; Challis D; McIntosh R; Parker A; Brown B; Rome R; Allen D; Grant P; Hyde S; Laurie R; Robbie M; Healy D, 2014, 'Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer', Scientific Reports, vol. 4, http://dx.doi.org/10.1038/srep04669
    Journal articles | 2014
    Professor Murray David Norris
    Cheung L; Flemming CL; Watt F; Masada N; Yu DMT; Huynh T; Conseil G; Tivnan A; Polinsky A; Gudkov AV; Munoz MA; Vishvanath A; Cooper DMF; Henderson MJ; Cole SPC; Fletcher JI; Haber M; Norris MD, 2014, 'High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)', Biochemical Pharmacology, vol. 91, pp. 97 - 108, http://dx.doi.org/10.1016/j.bcp.2014.05.023
    Journal articles | 2014
    Professor Murray David Norris
    Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, vol. 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032
    Journal articles | 2014
    Professor Murray David Norris
    Norris MD, 2014, 'Neuroblastoma: molecular targets and novel therapies', Pathology, vol. 46, pp. S36 - S36, http://dx.doi.org/10.1097/01.pat.0000454208.74479.75
    Journal articles | 2014
    Professor Murray David Norris
    Heong V; Topp M; Rutkowski R; Ananda S; Wong S; Swisher E; Lindeman G; Haber M; Norris MD; Haluska P; Wakefield M; Bowtell D; Scott CL; Lindeman G, 2014, 'OP0024 Use of novel patient-derived xenografts and molecular subtyping to improve precision medicine in high-grade serous ovarian cancer', European Journal of Cancer, vol. 50, pp. e9 - e9, http://dx.doi.org/10.1016/j.ejca.2014.03.042
    Journal articles | 2014
    Professor Murray David Norris
    Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, vol. 50, pp. 135 - 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7
    Journal articles | 2013
    Professor Murray David Norris
    Liu PY; Xu N; Malyukova A; Scarlett CJ; Sun YT; Zhang XD; Ling D; Su SP; Nelson CA; Chang DK; Koach J; Tee AE; Haber M; Norris MD; Rooman I; Toon C; Xue C; Cheung B; Kumar S; Marshall GM; Biankin AV; Liu T, 2013, 'The histone deacetylase SIRT2 stabilizes Myc oncoproteins', Cell Death and Differentiation, vol. 20, pp. 503 - 514, http://dx.doi.org/10.1038/cdd.2012.147
    Journal articles | 2013
    Professor Murray David Norris
    Kim PY; Rahmanto AS; Tan O; Norris MD; Haber M; Marshall GM; Cheung BB, 2013, 'TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells', Apoptosis, vol. 18, pp. 639 - 651, http://dx.doi.org/10.1007/s10495-013-0813-y
    Journal articles | 2013
    Professor Murray David Norris
    Johnatty SE; Beesley J; Gao B; Chen X; Lu Y; Law MH; Henderson MJ; Russell AJ; Hedditch EL; Emmanuel C; Fereday S; Webb PM; Goode EL; Vierkant RA; Fridley BL; Cunningham JM; Fasching PA; Beckmann MW; Ekici AB; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Brown R; Paul J; Lambrechts S; Despierre E; Vergote I; Lester J; Karlan BY; Heitz F; Du Bois A; Harter P; Schwaab I; Bean Y; Pejovic T; Levine DA; Goodman MT; Camey ME; Thompson PJ; Lurie G; Shildkraut J; Berchuck A; Terry KL; Cramer DW; Norris MD; Haber M; MacGregor S; DeFazio A; Chenevix-Trench G, 2013, 'ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and the Cancer Genome Atlas', Gynecologic Oncology, vol. 131, pp. 8 - 14, http://dx.doi.org/10.1016/j.ygyno.2013.07.107
    Journal articles | 2013
    Professor Murray David Norris
    Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, vol. 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205
    Journal articles | 2013
    Professor Murray David Norris
    Sekyere E; Thomas WD; Keating J; Calao M; Cui HJ; Chen JB; Raif A; Jankowski K; Cheung B; Davies NP NP; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation', Oncogene, vol. 32, pp. 3616 - 3626, http://dx.doi.org/10.1038/onc.2012.368
    Journal articles | 2013
    Professor Murray David Norris
    Marshall GM; Dalla Pozza L; Sutton R; Ng A; De Groot-Kruseman HA; Van Der Velden VH; Venn NC; Van Den Berg H; De Bont ESJM; Maarten Egeler R; Hoogerbrugge PM; Kaspers GJL; Bierings MB; Van Der Schoot E; Van Dongen J; Law T; Cross S; Mueller H; De Haas V; Haber M; Révész T; Alvaro F; Suppiah R; Norris MD; Pieters R, 2013, 'High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation', Leukemia, vol. 27, pp. 1497 - 1503, http://dx.doi.org/10.1038/leu.2013.44
    Journal articles | 2013
    Professor Murray David Norris
    Karsa M; Dalla Pozza L; Venn NC; Law T; Shi R; Giles JE; Bahar AY; Cross S; Catchpoole D; Haber M; Marshall GM; Norris MD; Sutton R, 2013, 'Improving the Identification of High Risk Precursor B Acute Lymphoblastic Leukemia Patients with Earlier Quantification of Minimal Residual Disease', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0076455
    Journal articles | 2013
    Professor Murray David Norris
    Malyukova A; Papa R; O'Brien R; Giles JE; Trahair TN; Pozza LD; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Marshall GM; Giles J, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, vol. 27, pp. 1053 - 1062, http://dx.doi.org/10.1038/leu.2012.361
    Journal articles | 2013
    Professor Murray David Norris
    Dietrich PA; Norris MD; Wang JY, 2013, 'GPR84, a Proinflammatory Receptor, Sustains Wnt/β-Catenin Signaling In Leukemic Stem Cells For Maintenance Of MLL-AF9-Induced Leukemogenesis', Blood, vol. 122, pp. 3781 - 3781, http://dx.doi.org/10.1182/blood.v122.21.3781.3781
    Journal articles | 2013
    Professor Murray David Norris
    Burkhart CA; Haber M; Norris MD; Gudkov AV; Nikiforov MA, 2013, 'Cell-based methods for the identification of Myc-inhibitory small molecules', Methods in Molecular Biology, vol. 1012, pp. 255 - 264, http://dx.doi.org/10.1007/978-1-62703-429-6_18
    Journal articles | 2012
    Professor Murray David Norris
    Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, vol. 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162
    Journal articles | 2012
    Professor Murray David Norris
    Cheung BB; Koach J; Tan O; Kim P; Bell J; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris MD; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott J; Cooper C; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro', Journal of Pathology, vol. 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986
    Journal articles | 2012
    Professor Murray David Norris
    Huynh T; Norris MD; Haber M; Henderson MJ, 2012, 'ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma', FRONTIERS IN ONCOLOGY, vol. 2, http://dx.doi.org/10.3389/fonc.2012.00178
    Journal articles | 2012
    Professor Murray David Norris
    Venn NC; Van der velden VHJ; De bie M; Waanders E; Giles JE; Law T; Kuiper RP; de Haas V; Mullighan CG; Haber M; Marshall GM; Norris MD; Van dongen JJM; Sutton R; Giles J; Law T, 2012, 'Highly sensitive MRD tests for ALL based on the IKZF1 Delta 3-6 microdeletion', Leukemia, vol. 26, pp. 1414 - 1416, http://dx.doi.org/10.1038/leu.2011.348
    Journal articles | 2012
    Professor Murray David Norris
    Lau DT; Hesson L; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma', Clinical Cancer Research, vol. 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294
    Journal articles | 2012
    Professor Murray David Norris
    Fletcher JI; Gherardi S; Murray J; Burkhart C; Russell A; Valli E; Smith J; Oberthuer A; Ashton LJ; London WB; Marshall GM; Norris MD; Perini G; Haber M, 2012, 'N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma', Cancer Research, vol. 72, pp. 845 - 853, http://dx.doi.org/10.1158/0008-5472.CAN-11-1885
    Journal articles | 2012
    Professor Murray David Norris
    Wang JY; Sprod O; Haber M; Norris MD, 2012, 'Epigenetic Elimination of Mixed-Lineage Leukemia Leukemic Stem Cells by a Potent Small Molecule PRC2 Inhibitor.', Blood, vol. 120, pp. 2456 - 2456, http://dx.doi.org/10.1182/blood.v120.21.2456.2456
    Journal articles | 2012
    Professor Murray David Norris
    Lau DT; Hesson LB; Norris MD; Haber M; Marshall GM; Ashton LJ, 2012, 'Prognostic significance of promoter DNA methylation in patients with neuroblastoma', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1425
    Journal articles | 2012
    Professor Murray David Norris
    Lau DT; Hesson LB; Norris MD; Marshall G; Haber M; Ashton LJ, 2012, 'Abstract 68: Beyond GWAS: The prognostic significance of promoter DNA methylation in patients with neuroblastoma.', Cancer Epidemiology Biomarkers & Prevention, vol. 21, pp. 68 - 68, http://dx.doi.org/10.1158/1055-9965.gwas-68
    Journal articles | 2011
    Professor Murray David Norris
    Lau DTT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'HLA-G polymorphisms, genetic susceptibility, and clinical outcome in chidlhood neuroblastoma', Tissue Antigens, vol. 78, pp. 421 - 427, http://dx.doi.org/10.1111/j.1399-0039.2011.01781.x
    Journal articles | 2011
    Professor Murray David Norris
    Porro A; Iraci N; Soverini S; Diolaiti D; Gherardi S; Terragna C; Durante S; Valli E; Kalebic T; Bernardoni R; Perrod C; Haber M; Norris MD; Baccarani M; Martinelli G; Perini G, 2011, 'c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34(+) Hematopoietic Progenitor Cells', Molecular Cancer Research, vol. 9, pp. 1054 - 1066, http://dx.doi.org/10.1158/1541-7786.MCR-10-0510
    Journal articles | 2011
    Professor Murray David Norris
    Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, vol. 7, pp. e1 - e14, http://dx.doi.org/10.1371/journal.pgen.1002135
    Journal articles | 2011
    Professor Murray David Norris
    Pajic M; Murray JE; Marshall GM; Cole SPC; Norris MD; Haber M, 2011, 'ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript', Pharmacogenetics and Genomics, vol. 21, pp. 270 - 279, http://dx.doi.org/10.1097/FPC.00b013e328343dd5f
    Journal articles | 2011
    Professor Murray David Norris
    Henderson M; Haber M; Porro A; Munoz M; Xue C; Murray JE; Flemming C; Smith J; Fletcher JI; Gherardi S; Kwek C; Russell AJ; Valli E; London WB; Buxton AB; Ashton LJ; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Norris MD, 2011, 'ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux', Journal of the National Cancer Institute, vol. 103, pp. 1236 - 1251, http://dx.doi.org/10.1093/jcni/djr256
    Journal articles | 2011
    Professor Murray David Norris
    Neiron Z; Jankowski K; Murray J; Champion S; Norris MD; Haber M; Fletcher JI, 2011, 'Development of organ-selective neuroblastoma cell lines to identify genes mediating bone marrow and liver colonization', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-5237
    Journal articles | 2010
    Professor Murray David Norris
    Liu T, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, vol. 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340
    Journal articles | 2010
    Professor Murray David Norris
    Milne E; Royle JA; Miller M; Bower C; de klerk NH; Bailey HD; Van brockxmeer F; Attia J; Scott RJ; Norris MD; Haber M; Thompson JR; Fritschi L; Marshall GM; Armstrong B, 2010, 'Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring', International Journal of Cancer, vol. 126, pp. 2690 - 2699, http://dx.doi.org/10.1002/ijc.24969
    Journal articles | 2010
    Professor Murray David Norris
    Swarbrick A; Woods SL; Shaw A; Balakrishnan A; Phua Y; Nguyen A; Chanthery Y; Lim L; Ashton LJ; Judson RL; Blelloch R; Huskey N; Haber M; Norris MD; Lengyel P; Hackett CS; Preiss T; Chetcuti A; Sullivan CS; Marcusson EG; Weiss W; L''Etoile N; Goga A, 2010, 'miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma', Nature Medicine, vol. 16, pp. 1134 - 1141, http://dx.doi.org/10.1038/nm.2227
    Journal articles | 2010
    Professor Murray David Norris
    Fletcher JI; Haber M; Henderson M; Norris MD, 2010, 'ABC transporters in cancer: more than just drug efflux pumps', Nature Reviews Cancer, vol. 10, pp. 147 - 156, http://dx.doi.org/10.1038/nrc2789
    Journal articles | 2010
    Professor Murray David Norris
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, vol. 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332
    Journal articles | 2010
    Professor Murray David Norris
    Porro A; Haber M; Diolaiti D; Iraci N; Henderson M; Gherardi S; Valli E; Munoz M; Xue C; Flemming C; Schwab M; Wong JH; Marshall GM; Della valle G; Norris MD; Perini G, 2010, 'Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells', The Journal of Biological Chemistry, vol. 285, pp. 19532 - 19543, http://dx.doi.org/10.1074/jbc.M109.078584
    Journal articles | 2010
    Professor Murray David Norris
    Liu T, 2010, 'Opposing Effects of Two Tissue Transglutaminase Protein Isoforms in Neuroblastoma Cell Differentiation', The Journal of Biological Chemistry, vol. 285, pp. 3561 - 3567, http://dx.doi.org/10.1074/jbc.M109.053041
    Journal articles | 2010
    Professor Murray David Norris
    Bhadri V; McGregor MR; Venn NC; Hackenberg N; Russell SJ; Norris MD; Haber M; Sutton R; Marshall GM, 2010, 'Isolated testicular relapse after allo-SCT in boys with ALL: outcome without second transplant', Bone Marrow Transplantation, vol. 45, pp. 397 - 399, http://dx.doi.org/10.1038/bmt.2009.138
    Journal articles | 2009
    Professor Murray David Norris
    Thomas WD; Chen J; Gao YR; Cheung BB; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM, 2009, 'Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression', Oncogene, vol. 28, pp. 1605 - 1615, http://dx.doi.org/10.1038/onc.2009.3
    Journal articles | 2009
    Professor Murray David Norris
    Raif A; Marshall GM; Bell J; Koach J; Tan O; D'andreti C; Thomas WD; Sekyere E; Norris MD; Haber M; Kavallaris M; Cheung BB, 2009, 'The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation', Cancer Letters, vol. 277, pp. 82 - 90, http://dx.doi.org/10.1016/j.canlet.2008.11.030
    Journal articles | 2009
    Professor Murray David Norris
    Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, vol. 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225
    Journal articles | 2009
    Professor Murray David Norris
    Ashton LJ; Gifford AJ; Kwan E; Lingwood A; Lau DTT; Marshall GM; Haber M; Norris MD, 2009, 'Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia', Leukemia, vol. 23, pp. 1348 - 1351, http://dx.doi.org/10.1038/leu.2009.67
    Journal articles | 2009
    Professor Murray David Norris
    Dilda P; Decollogne SM; Weerakoon L; Norris MD; Haber M; Allen JD; Hogg PJ, 2009, 'Optimization of the antitumor efficacy of a synthetic mitochondrial toxin by increasing the residence time in the cytosol', Journal of Medicinal Chemistry, vol. 52, pp. 6209 - 6216, http://dx.doi.org/10.1021/jm9008339
    Journal articles | 2009
    Professor Murray David Norris
    Liu T, 2009, 'Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors', European Journal of Cancer, vol. 45, pp. 1846 - 1854, http://dx.doi.org/10.1016/j.ejca.2009.03.002
    Journal articles | 2009
    Professor Murray David Norris
    Sutton R; Venn NC; Tolisano J; Bahar AY; Giles JE; Ashton LJ; Teague L; Rigutto G; Waters K; Marshall GM; Haber M; Norris MD; Giles J, 2009, 'Clinical significance of minimal residual disease at day 15 and at the end of therapy in childhood acute lymphoblastic leukaemia', British Journal of Haematology, vol. 146, pp. 292 - 299, http://dx.doi.org/10.1111/j.1365-2141.2009.07744.x
    Journal articles | 2009
    Professor Murray David Norris
    Morley A; Latham S; Brisco MJ; Sykes PJ; Sutton R; Hughes E; Wilczek V; Budgen B; Van Zanten K; Kuss B; Venn NC; Norris MD; Crock C; Storey CE; Revesz T; Waters K, 2009, 'Sensitive and specific measurement of minimal residual disease in acute lymphoblastic leukemia', Journal of Molecular Diagnostics, vol. 11, pp. 201 - 210, http://dx.doi.org/10.2353/jmoldx.2009.080048
    Journal articles | 2009
    Professor Murray David Norris
    Burkhart CA; Watt F; Murray J; Pajic M; Prokvolit A; Xue C; Flemming C; Smith J; Purmal A; Isachenko N; Komarov PG; Gurova KV; Sartorelli AC; Marshall GM; Norris MD; Gudkov AV; Haber M, 2009, 'Small-Molecule Multidrug Resistance-Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma', Cancer research, vol. 69, pp. 6573 - 6580, http://dx.doi.org/10.1158/0008-5472.CAN-09-1075
    Journal articles | 2009
    Professor Murray David Norris
    Bohlken A; Cheung B; Bell J; Koach J; Smith S; Sekyere E; Thomas WD; Norris MD; Haber M; Lovejoy DB; Richardson DR; Marshall GM, 2009, 'ATP7A is a novel target of retinoic acid receptor beta(2) in neuroblastoma cells', British Journal of Cancer, vol. 100, pp. 96 - 105, http://dx.doi.org/10.1038/sj.bjc.6604833
    Journal articles | 2009
    Professor Murray David Norris
    Brisco MJ; Latham S; Sutton R; Hughes E; Wilczek V; Van Zanten K; Budgen B; Malec M; Sykes PJ; Kuss BJ; Waters K; Venn NC; Giles J; Haber M; Norris MD; Marshall GM; Morley AA; Bahar ; Giles J, 2009, 'Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia', Journal of Molecular Diagnostics, vol. 11, pp. 194 - 200, http://dx.doi.org/10.2353/jmoldx.2009.080047
    Journal articles | 2008
    Professor Murray David Norris
    Williams BB; Wall M; Miao RY; Williams B; Bertoncello I; Kershaw MH; Mantamadiotis T; Haber M; Norris MD; Gautam A; Darcy PK; Ramsay RG, 2008, 'Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer', Cancer Immunology and Immunotherapy, vol. 57, pp. 1635 - 1645, http://dx.doi.org/10.1007/s00262-008-0497-2
    Journal articles | 2008
    Professor Murray David Norris
    Henderson M; Choi S; Beesley A; Sutton R; Venn NC; Marshall GM; Kees UR; Haber M; Norris MD, 2008, 'Mechanism of relapse in pediatric acute lymphoblastic leukemia', Cell Cycle, vol. 7, pp. 1315 - 1320, http://dx.doi.org/10.4161/cc.7.10.5885
    Journal articles | 2008
    Professor Murray David Norris
    Hogarty MD; Norris MD; Davis K; Liu X; Evangeliou NF; Hayes CS; Pawel B; Guo R; Zhao H; Sekyere E; Keating J; Thomas WD; Cheng NC; Murray JE; Smith J; Sutton R; Venn NC; London WB; Buxton A; Gilmour SK; Marshall GM; Haber M, 2008, 'ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma', Cancer research, vol. 68, pp. 9735 - 9745, http://dx.doi.org/10.1158/0008-5472.CAN-07-6866
    Journal articles | 2008
    Professor Murray David Norris
    Sutton R; Kwan EN; Giles JE; Venn NC; Tran S; Hackenberg N; Dalla Pozza L; Marshall GM; Haber M; van der Velden V; Norris MD; Bahar ; Giles J, 2008, 'Improving minimal residual disease detection in precursor B-ALL based on immunoglobulin-j and heavy-chain gene rearrangements', Leukemia, vol. 22, pp. 2265 - 2267, http://dx.doi.org/10.1038/leu.2008.121
    Journal articles | 2008
    Professor Murray David Norris
    Sutton R; Lonergan MA; Tapp H; Venn NC; Haber M; O Brien T; Alvaro F; Revesz T; Norris MD, 2008, 'Two cases of hypereosinophilia and high-risk acute lymphoblastic leukemia', Leukemia, vol. 22, pp. 1463 - 1465, http://dx.doi.org/10.1038/sj.leu.2405096
    Journal articles | 2008
    Professor Murray David Norris
    Henderson M; Choi S; Beesley A; Baker DL; Wright DC; Papa R; Murch A; Campbell L; Lock RB; Norris MD; Haber M; Kees UR, 2008, 'A xenograft model of infant leukaemia reveals a complex MLL translocation', British Journal of Haematology, vol. 140, pp. 716 - 719, http://dx.doi.org/10.1111/j.1365-2141.2007.06966.x
    Journal articles | 2007
    Professor Murray David Norris
    Liu T, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 18682 - 18687, http://dx.doi.org/10.1073/pnas.0705524104
    Journal articles | 2007
    Professor Murray David Norris
    Munoz MA; Henderson M; Haber M; Norris MD, 2007, 'Role of the MRP1/ABCC1 multidrug transporter protein in cancer', IUBMB Life, vol. 59, pp. 752 - 757, http://dx.doi.org/10.1080/15216540701736285
    Journal articles | 2007
    Professor Murray David Norris
    Choi S; Henderson M; Kwan EN; Sutton R; Giles J; Venn NC; Marshall GM; Haber M; Norris MD; Giles J, 2007, 'Relapse in children with acute lymphoblastic leukaemia involving selection of a pre-existing drug resistant subclone', Blood, vol. 110, pp. 632 - 639, http://dx.doi.org/10.1182/blood-2007-01-067785
    Journal articles | 2007
    Professor Murray David Norris
    Cheng AJ; Cheng NC; Smith J; Murray JE; Flemming C; Marshall GM; Norris MD; Haber M, 2007, 'Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma', European Journal of Cancer, vol. 43, pp. 1467 - 1475, http://dx.doi.org/10.1016/j.ejca.2007.03.008
    Journal articles | 2007
    Professor Murray David Norris
    Xue C; Haber M; Flemming C; Marshall GM; Lock RB; Mackenzie K; Norris MD; Gurova K; Gudkov A, 2007, 'p53 determines multidrug sensitivity of childhood neuroblastoma.', Cancer research, vol. 67, pp. 10351 - 10360, http://dx.doi.org/10.1158/0008-5472.CAN-06-4345
    Journal articles | 2007
    Professor Murray David Norris
    Liu T, 2007, 'Enhancing the anti-angiogenic action of histone deacetylase inhibitors', Molecular Cancer, vol. 6, pp. 68 - 79, http://dx.doi.org/10.1186/1476-4598-6-68
    Journal articles | 2007
    Professor Murray David Norris
    Ashton LJ; Murray JE; Haber M; Marshall GM; Norris MD; Ashley DM, 2007, 'Polymorphisms in genes encoding drug metabolising enzymes and their influence on the outcome of children with neuroblastoma.', Pharmacogenetics and Genomics, vol. 17, pp. 709 - 717, http://dx.doi.org/10.1097/FPC.0b013e3280e1cc92
    Journal articles | 2007
    Professor Murray David Norris
    Norris MD; Smith J; Kwek A; Flemming C; Cohn SL; London WB; Buxton A; Marshall GM; Haber M, 2007, 'Expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3, and ABCC4/MRP4 are powerful predictors of clinical outcome in childhood neuroblastoma', Journal of Clinical Oncology, vol. 25, pp. 9524 - 9524, http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9524
    Journal articles | 2007
    Professor Murray David Norris
    Liu T; Tee AEL; Porro A; Smith SA; Dwarte T; Pei YL; Iraci N; Sekyere E; Haber M; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (Proceedings of the National Academy of Science of the United States of America (November 20, 2007) 104; 47, (18682-18687) DOI: 10.1073/pnas.0705524104)', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 21021, http://dx.doi.org/10.1073/pnas.0711060105
    Journal articles | 2007
    Professor Murray David Norris
    Liu T; Tee EL; Porro A; Smith SA; Dwarte T; Norris MD; Diolaiti D; Della Valle G; Perini G; Marshall GM, 2007, 'Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis (vol 104, pg 18682, 2007)', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, pp. 21021 - 21021, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252077400076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2006
    Professor Murray David Norris
    Haber M; Smith J; Bordow SB; Flemming C; Cohn SL; London WB; Marshall GM; Norris MD, 2006, 'Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma', Journal of Clinical Oncology, vol. 24, pp. 1546 - 1553, http://dx.doi.org/10.1200/JCO.2005.01.6196
    Journal articles | 2006
    Professor Murray David Norris
    Cheung BB; Bell J; Raif A; Bohlken A; Yan J; Poljak A; Smith S; Lee M; Thomas WD; Kavallaris M; Norris MD; Haber M; Liu H; Zajchowski D; Marshall GM; bell , 2006, 'The estrogen-responsive B box protein is a novel regulator of the retinoid signal', The Journal of Biological Chemistry, vol. 281, pp. 18246 - 18256, http://dx.doi.org/10.1074/jbc.M600879200
    Journal articles | 2006
    Professor Murray David Norris
    Murray J; Burkhart CA; Watt F; Pajic M; Flemming C; Smith J; Gudkov AV; Haber M; Norris MD, 2006, '169 POSTER Sensitisation of neuroblastoma tumours to chemotherapy by use of a novel class of MRP1 small molecule inhibitor', European Journal of Cancer Supplements, vol. 4, pp. 54 - 54, http://dx.doi.org/10.1016/s1359-6349(06)70175-6
    Journal articles | 2005
    Professor Murray David Norris
    Laughton SJ; Ashton LJ; Kwan EN; Norris MD; Haber M; Marshall GM, 2005, 'Early responses to chemotherapy of normal and malignant hematologic cells are prognostic in childhood acute lymphoblastic leukaemia', Journal of Clinical Oncology, vol. 23, pp. 2264 - 2271, http://dx.doi.org/10.1200/JCO.2005.04.012
    Journal articles | 2005
    Professor Murray David Norris
    Liu T, 2005, 'The retinoid anticancer signal: mechanisms of target gene regulation', British Journal of Cancer, vol. 93, pp. 310 - 318, http://dx.doi.org/10.1038/sj.bjc.6602700
    Journal articles | 2005
    Professor Murray David Norris
    Norris MD; Smith J; Tanabe K; Tobin P; Flemming C; Scheffer G; Wielinga P; Cohn SL; London WB; Marshall GM; Allen JA; Haber M, 2005, 'Expression of multidrug ptransporter MRP4/ABCC4 is a marker of poor prognosis in nueroblastoma and confers resistance to irinotecan in vitro', Molecular Cancer Therapeutics, vol. 4, pp. 547 - 553, http://dx.doi.org/10.1158/1535-7163.MCT-04-0161
    Journal articles | 2005
    Professor Murray David Norris
    Pajic M; Norris MD; Cohn RJ; Haber M, 2005, 'The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome', Cancer Letters, vol. 228, pp. 241 - 246, http://dx.doi.org/10.1016/j.canlet.2005.01.060
    Journal articles | 2005
    Professor Murray David Norris
    Ziegler DS; Cohn RJ; Duffy B; Sutton R; Norris MD, 2005, 'PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection', Leukemia Research, vol. 29, pp. 111 - 112, http://dx.doi.org/10.1016/j.leukres.2004.03.023
    Journal articles | 2005
    Professor Murray David Norris
    Norris MD; Smith J; Tanabe K; Tobin P; Flemming C; Scheffer G; Wielinga P; Cohn SL; London WB; Marshall GM; Allen JA; Haber M, 2005, 'Expression of multi-drug transport MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro', Molecular Cancer Therapeutics, vol. 4, pp. 547 - 553
    Journal articles | 2004
    Professor Murray David Norris
    Don S; Verrills NM; Liaw T; Haber M; Norris MD; Kavallaris M, 2004, 'Neuronal-associated microtubule proteins class III B-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs.', Molecular Cancer Therapeutics, vol. 3, pp. 1137 - 1146
    Journal articles | 2004
    Professor Murray David Norris
    Lastowska M; Chung Y; Ching Cheng C; Haber M; Norris MD; Kees UR; Pearson AA; Jackson M, 2004, 'Regions syntenic to human 17q are gained in mouse and rat neuroblastoma.', Genes Chromosomes and Cancer, vol. 40, pp. 158 - 163, http://dx.doi.org/10.1002/gcc.20031
    Journal articles | 2004
    Professor Murray David Norris
    Hansford LM; Thomas WD; Keating JM; Burkhart C; Armati PJ; Weiss WA; Peaston AE; Norris MD; Haber M; Marshall GM, 2004, 'Mechanisms of embryonal tumor initination: Distinct roles for MycN expression and MYCN amlification.', Proceedings of the National Academy of Sciences of the United States of America, vol. 101, pp. 12664 - 12669, http://dx.doi.org/10.1073/pnas.0401083101
    Journal articles | 2004
    Professor Murray David Norris
    Liem N; Papa R; Milross CG; Schmid M; Tajbakhsh M; Choi S; Ramirez C; Rice AM; Haber M; Norris MD; Lock RB, 2004, 'Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies', Blood, vol. 103, pp. 3905 - 3914, http://dx.doi.org/10.1182/blood-2003-08-2911
    Journal articles | 2004
    Professor Murray David Norris
    Manohar CF; Bray JA; Salwen H; Madafiglio J; Cheng AJ; Flemming C; Marshall GM; Norris MD; Haber M; Cohn SL, 2004, 'MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma', Oncogene, vol. 23, pp. 753 - 762, http://dx.doi.org/10.1038/sj.onc.1207151
    Journal articles | 2004
    Professor Murray David Norris
    Misra AK; Sartor M; Sutton R; Venn NC; Cross S; Bradstock K; Norris M; Dalla-Pozza L, 2004, 'Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: A Comparative Study of Flow Cytometry and Quantitative Real-Time Polymerase Chain Reaction (RQ-PCR).', Blood, vol. 104, pp. 4504 - 4504, http://dx.doi.org/10.1182/blood.v104.11.4504.4504
    Journal articles | 2003
    Professor Murray David Norris
    Marshall GM; Haber M; Kwan EN; Zhu L; Ferrara D; Xue C; Brisco MJ; Sykes PJ; Morley A; Webster B; Dalla Pozza L; Waters K; Norris MD, 2003, 'Importance of minimal residual disease testing during teh second year of therapy for children with acute lymphoblastic leukemia', Journal of Clinical Oncology, vol. 21, pp. 704 - 709, http://dx.doi.org/10.1200/JCO.2003.10.080
    Journal articles | 2003
    Professor Murray David Norris
    Nguyen TG; Hocker JE; Thomas WD; Smith SA; Norris MD; Haber M; Cheung BB; Marshall GM, 2003, 'Combined RAR and RXr-specific ligands overcome N-myc-associated retinoid resistance in neuroblastoma cells', Biochemical and Biophysical Research Communications, vol. 302, pp. 462 - 468, http://dx.doi.org/10.1016/S0006-291X(03)00177-3
    Journal articles | 2003
    Professor Murray David Norris
    Burkhart CA; Cheng AJ; Madafiglio J; Kavallaris M; Mili M; Marshall GM; Weiss WA; Khachigian LM; Norris MD; Haber M, 2003, 'Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma', Journal of National Cancer Institute, vol. 95, pp. 1394 - 1403, http://dx.doi.org/10.1093/jnci/djg045
    Journal articles | 2003
    Professor Murray David Norris
    Verrills NM; Flemming C; Liu M; Ivery M; Cobon GS; Norris MD; Haber M; Kavallaris M, 2003, 'Microtubule alterations and mutations induced by desoxyepothilone B: Implications for drug-target', Chemistry and biology, vol. 10, pp. 597 - 607, http://dx.doi.org/10.1016/S1074-5521(03)00141-8
    Journal articles | 2003
    Professor Murray David Norris
    Pearson AJ; Haber M; Norris MD; Xue C; Flemming C; Lunec J; Tweddle D, 2003, 'The p53 pathway and its inactivitation in neuroblastoma', Cancer Letters, vol. 197, pp. 93 - 98, http://dx.doi.org/10.1016/S0304-3835(03)00088-0
    Journal articles | 2003
    Professor Murray David Norris
    Hansford LM; Smith S; Haber M; Norris MD; Cheung BB; Marshall GM, 2003, 'Cloning and characterisation of the human neural cell adhesion molecule, (CNTN4) ( alias BIG-2)', Cytogenetic and Genome Research, vol. 101, pp. 1 - 17, http://dx.doi.org/10.1159/000073412
    Journal articles | 2003
    Professor Murray David Norris
    Cheung BB; Yan JX; Smith SA; Nguyen TG; Lee M; Kavallaris M; Norris MD; Haber M; Marshall GM, 2003, 'Growth inhibitory retinoid effects after recruitment of retinoid X receptor B to the retinoic acid receptor B promoter', International Journal of Cancer, vol. 105, pp. 856 - 867, http://dx.doi.org/10.1002/ijc.11153
    Journal articles | 2003
    Professor Murray David Norris
    Marshall G; Norris M; Haber M, 2003, 'In Reply:', Journal of Clinical Oncology, vol. 21, pp. 4464 - 4465, http://dx.doi.org/10.1200/jco.2003.99.188
    Journal articles | 2002
    Professor Murray David Norris
    Lock RB; Liem N; Farnsworth ML; Milross CG; Xue C; Tajbakhsh M; Haber M; Norris MD; Marshall GM; Rice AM, 2002, 'The non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of Childhood acute lymphblastic leukemia reveals intrinsic differences in biological characteristics at diagnosis and relapse', Blood, vol. 99, pp. 4100 - 4108, http://dx.doi.org/10.1182/blood.V99.11.4100
    Journal articles | 2002
    Professor Murray David Norris
    Gifford AJ; Haber M; Witt T; Whetstine JR; Taub JW; Matherly LH; Norris MD, 2002, 'Role of E45K reduced folate carrier gene mutation in methotrexate resistance in human leukaemia cells', Leukemia, vol. 16, pp. 2379 - 2387, http://dx.doi.org/10.1038/sj.leu.2402655
    Journal articles | 2002
    Professor Murray David Norris
    Burkhart CA; Norris MD; Haber M, 2002, 'A simple method for the isolation of genomic DNA from mouse tail free of real-time PCR inhibitors', Journal of Biochemical and Biophysical Methods, vol. 52, pp. 145 - 149, http://dx.doi.org/10.1016/S0165-022X(02)00052-0
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Madafiglio J; Gilbert J; Marshall GM; Haber M, 2001, 'Relationship between histopathological features, MYCN amplification, and prognosis: A UKCCSG study', Medical and Pediatric Oncology, vol. 36, pp. 169 - 176, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<169::AID-MPO1041>3.0.CO;2-U
    Journal articles | 2001
    Professor Murray David Norris
    Whetstine JR; Gifford AJ; Witt T; Liu X; Flatley RM; Norris MD; Haber M; Taub JW; Ravindranath Y; Matherly LH, 2001, 'Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G.A variant at position 80 and transport properties of the his27 And Arg27 carriers', Clinical Cancer Research, vol. 7, pp. 3416 - 3422, http://clincancerres.aacrjournals.org/content/7/11/3416.full-text.pdf
    Journal articles | 2001
    Professor Murray David Norris
    Marshall GM; Norris MD; Lock RB; Peaston AE; Gardaneh M; Franco VA; Hocker JE; Murphy K; Farnsworth ML; Catchpoole DR; Haber M, 2001, 'MRP1 gene expression level regulates the death and differentation response of neuroblastoma cells', British Journal of Cancer, vol. 85, pp. 1564 - 1571, http://dx.doi.org/10.1054/bjoc.2001.2144
    Journal articles | 2001
    Professor Murray David Norris
    Kavallaris M; Tait AS; Norris MD; Haber M; Walsh B; He L; Horwitz SB, 2001, 'Multiple microtubule alterations are associated with vinca alkaloid resistance in human leukemia cells', Cancer research, vol. 61, pp. 5803 - 5809
    Journal articles | 2001
    Professor Murray David Norris
    Catts VS; Haber M; Norris MD; Lutze-Mann L; Lock RB, 2001, 'High Level resistance to Glucocorticoids, assosiated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance', Leukemia, vol. 15, pp. 929 - 935, http://dx.doi.org/10.1038/sj.leu.2402128
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Madafiglio J; Gilbert J; Marshall GM; Haber M, 2001, 'Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin', MEDICAL AND PEDIATRIC ONCOLOGY, vol. 36, pp. 177 - 180, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<177::AID-MPO1042>3.0.CO;2-Q
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Gilbert J; Smith SA; Marshall GM; Salwen H; Cohn SL; Haber M, 2001, 'Genomic and allelic expression status of the p73 gene in human neuroblastoma', Medical and Pediatric Oncology, vol. 36, pp. 45 - 47, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<45::AID-MPO1012>3.0.CO;2-E
    Journal articles | 2001
    Professor Murray David Norris
    Kwan E; Lal A; Haber M; Norris MD; Marshall GM, 2001, 'Detection of minimal residual disease in peripheral blood prior to clonical relapse of childhood acute lympohoblastic leukaemia using PCR', Molecular and Cellular Probes, vol. 15, pp. 99 - 103, http://dx.doi.org/10.1006/mcpr.2001.0348
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Gilbert J; Smith A; Marshall GM; Salwen H; Cohn JN; Haber M, 2001, 'Expression of the Putative Tumour Suppressor Gene, p73, in Neuroblastome and Other Childhood Tumours', Medical Pediatric Oncology, vol. 36, pp. 48 - 51, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<48::AID-MPO1013>3.0.CO;2-8
    Journal articles | 2001
    Professor Murray David Norris
    Ekert H; Vivekanandan S; Chow CW; Marshall GM; Haber M; Norris MD, 2001, 'Expression of GAGE genes in neuroblastoma by reverse transcription - polymerase chain reaction', Cancer Research Therapy and Control, vol. 11, pp. 197 - 203
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Marshall GM; Haber M; Gilbert J; Madafiglio J, 2001, 'Reversal of MRP-mediated drug resistance in cultured human neuroblastome cells by the quinlone antibiotic, difloxacin', Medical Pediatric Oncology, pp. 177 - 180
    Journal articles | 2001
    Professor Murray David Norris
    Norris MD; Gilbert J; Smith SA; Marshall GM; Salwen H; Cohn SL; Haber M, 2001, 'Expression of the putative tumour suppressor gene, p73, in neuroblastoma and other childhood tumours', Medical and Pediatric Oncology, vol. 36, pp. 48 - 51, http://dx.doi.org/10.1002/1096-911X(20010101)36:1<48::AID-MPO1013>3.0.CO;2-8
    Journal articles | 2000
    Professor Murray David Norris
    Cohn S; London WB; Huang K; Katzenstein HM; Salwen H; Reinhart T; Madafiglio J; Marshall GM; Norris MD; Haber M, 2000, 'MYCN expression is not prognostic of adverse outcomes in advanced-stage neuroblastoma with non-amplified MYCN', Journal of Clinical Oncology, vol. 18, pp. 3604 - 3613, http://dx.doi.org/10.1200/JCO.2000.18.21.3604
    Journal articles | 2000
    Professor Murray David Norris
    Norris MD; Burkhart CA; Marshall GM; Haber M, 2000, 'Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in murine neuroblastoma model', Medical and Pediatric Oncology, vol. 35, pp. 585 - 589, http://dx.doi.org/10.1002/1096-911X(20001201)35:6<585::AID-MPO20>3.0.CO;2-P
    Journal articles | 2000
    Professor Murray David Norris
    Kwan EN; Norris MD; Zhu L; Ferrara D; Marshall GM; Haber M, 2000, 'Simultaneous detection and quantification of minimal residual disease in childhood acute lymphoblastic leukaemia using real-time polymerase chain reaction', British Journal of Haematology, vol. 109, pp. 430 - 434, http://dx.doi.org/10.1046/j.1365-2141.2000.02029.x
    Journal articles | 2000
    Professor Murray David Norris
    Gardaneh M; Gilbert J; Haber M; Norris MD; Marshall GM, 2000, 'Synergy between 5` and 3` flanking regions of the human tyrosine hydroxylase gene ensures specific, high-level expression in neuroblastoma cells', Neuroscience Letters, vol. 292, pp. 147 - 150, http://dx.doi.org/10.1016/S0304-3940(00)01474-9
    Journal articles | 1999
    Professor Murray David Norris
    Haber PS; Norris MD; Apte MV; Rodgers SC; Norton ID; Pirola RC; Roberts-Thomson IC; Wilson JS, 1999, 'Alcoholic pancreatitis and polymorphisms of the variable length polythymidine tract in the cystic fibrosis (CFTR) gene', Alcoholism : Clinical and Experimental Research, vol. 23, pp. 509 - 512, http://dx.doi.org/10.1111/j.1530-0277.1999.tb04145.x
    Journal articles | 1999
    Professor Murray David Norris
    Gilbert J; Haber M; Bordow SB; Marshall GM; Norris MD, 1999, 'Use of tumor-specific gene expression for the differential diagnosis of neuroblastoma from other pediatric small-round-cell malignancies', American Journal of Pathology, vol. 155, pp. 17 - 21, http://dx.doi.org/10.1016/S0002-9440(10)65093-6
    Journal articles | 1999
    Professor Murray David Norris
    Marshall GM; Haber M; Kwan E; Zhou L; Ferrara D; Williams S; Brisco MJ; Morley A; Webster B; Dalla Pozza L; Tucker D; Waters K; Norris MD, 1999, 'The effect of late intensification of therapy in children with acute lymphoblastic leukaemia and minimal residual disease.', BLOOD, vol. 94, pp. 658A - 658A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790302970&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1999
    Professor Murray David Norris
    Haber M; Bordow SB; Gilbert J; Madafiglio J; Kavallaris M; Marshall GM; Mechetner EB; Fruehauf JP; Tee L; Cohn S; Salwen H; Schmidt ML; Norris MD; Gilbert J, 1999, 'Altered expression of the MYCN Oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells', Oncogene, vol. 18, pp. 2777 - 2782, http://dx.doi.org/10.1038/sj.onc.1202859
    Journal articles | 1998
    Professor Murray David Norris
    Gifford AJ; Kavallaris M; Madafiglio J; Matherly LH; Stewart BW; Haber M; Norris MD, 1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, vol. 78, pp. 176 - 181, http://dx.doi.org/10.1002/(SICI)1097-0215(19981005)78:2<176::AID-IJC10>3.0.CO;2-9
    Journal articles | 1998
    Professor Murray David Norris
    Bardow SB; Norris MD; Haber PS; Marshall GM; Haber M, 1998, 'Prognostic significance of MYCN oncgene expression in childhood neuroblastoma', Journal of Clinical Oncology, vol. 16, pp. 3286 - 3294, http://dx.doi.org/10.1200/JCO.1998.16.10.3286
    Journal articles | 1998
    Professor Murray David Norris
    Cheung BB; Hocker JE; Smith S; Norris MD; Haber M; Marshall GM, 1998, 'Favorable prognostic signifiance of high-level retinoic acid receptor B expression in neuroblastoma mediated by effects on cell cycle regulation', Oncogene, vol. 17, pp. 751 - 759, http://dx.doi.org/10.1038/sj.onc.1201982
    Journal articles | 1998
    Professor Murray David Norris
    Preston AE; Camacho M; Norris MD; Haber M; Marsh DJ; Robinson BG; Hyland V; Marshall GM, 1998, 'Absence of MEN2A- or 2B- type RET mutations in primary neuroblastoma tumour tissue', Molecular and Cellular Probes, vol. 12, pp. 239 - 242, http://dx.doi.org/10.1006/mcpr.1998.0181
    Journal articles | 1998
    Professor Murray David Norris
    Kavallaris M; Gardaneh M; Cheung BB; Camacho M; Hocker JE; Norris MD; Haber M; Marshall GM, 1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, vol. 18, pp. 1793 - 1798
    Journal articles | 1998
    Professor Murray David Norris
    Haber PS; Norton ID; Norris MD; Apte MV; Pirola RC; Roberts-Thomson IC; Wilson JS, 1998, 'Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis?', Gastroenterology, vol. 114, pp. A466 - A466, http://dx.doi.org/10.1016/s0016-5085(98)81884-2
    Journal articles | 1998
    Professor Murray David Norris
    Lal A; Kwan EN; Al Mahr M; Zhou L; Ferrara D; Tobias VH; O Gorman-Hughes DW; Haber M; Norris MD; Marshall GM, 1998, 'Molecular detection of acute Lymphoblastic Leukaemia in boys with testicular relapse', Molecular Pathology, vol. 51, pp. 277 - 281, http://dx.doi.org/10.1136/mp.51.5.277
    Journal articles | 1997
    Professor Murray David Norris
    Kavallaris M; Kuo DY; Burkhart CA; Regl DL; Norris MD; Haber M; Horwitz SB, 1997, 'TAXOL-RESISTANT EPITHELIAL OVARIAN TUMORS ARE ASSOCIATED WITH ALTERED EXPRESSION OF SPECIFIC {BETA}-TUBLIN ISOTYPES', Journal of Clinical Investigation, vol. 100, pp. 1282 - 1293, http://dx.doi.org/10.1172/JCI119642
    Journal articles | 1997
    Professor Murray David Norris
    Norris MD; Bordow SB; Haber PS; Marshall GM; Kavallaris M; Madafiglio J; Cohn S; Schmidt ML; Hipfner DR; Deeley RG; Cole SP; Haber M; Salwen H, 1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, vol. 33, pp. 1911 - 1916, http://dx.doi.org/10.1016/S0959-8049(97)00284-0
    Journal articles | 1997
    Professor Murray David Norris
    Haber M; Bordow SB; Haber PS; Marshall GM; Stewart BW; Norris MD, 1997, 'THE PROGNOSTIC VALUE OF MDR1 GENE EXPRESSION IN PRIMARY UNTREATED NEUROBLASTOMA', EUR Journal CANCER, vol. 33, pp. 2031 - 2036, http://dx.doi.org/10.1016/S0959-8049(97)00229-3
    Journal articles | 1997
    Professor Murray David Norris
    Norris MD; Kwan EN; Zhu L; Ferrara D; Marshall GM; Haber M, 1997, 'IMPROVED PCR ASSAY FOR THE DETECTION OF ANTIGEN RECEPTOR GENE REARRANGEMENTS', Journal of Biochemical and Biophysical Methods, vol. 36, pp. 3 - 10, http://dx.doi.org/10.1016/S0165-022X(97)00043-2
    Journal articles | 1997
    Professor Murray David Norris
    Marshall GM; Peaston AE; Hocker JE; Smith AJ; Hansford LM; Tobias VH; Norris MD; Haber M; Smith DD; Lorenzo MJ; Ponder BJ; Hancock JF, 1997, 'Expression of multiple endocrine neoplasia 2B ret in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behaviour in vivo, and activates jun kinase 1', Cancer research, vol. 57, pp. 5399 - 5405
    Journal articles | 1997
    Professor Murray David Norris
    Haber M; Kwan EN; Zhu L; Marshall GM; Norris MD, 1997, 'SENSITIVE NON- RADIOACTIVE PCR DETECTION OF CLONAL T-CELL RECEPTOR GAMMA GENE REARRANGEMENTS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA', British Journal of Haematology, vol. 98, pp. 995 - 998, http://dx.doi.org/10.1046/j.1365-2141.1997.3243143.x
    Journal articles | 1997
    Professor Murray David Norris
    Gilbert J; Norris MD; Marshall GM; Haber M, 1997, 'Low specificity of PGP9.5 expression for detection of micrometastatic neuroblastoma', British Journal of Cancer, vol. 75, pp. 1779 - 1781, http://dx.doi.org/10.1038/bjc.1997.303
    Journal articles | 1996
    Professor Murray David Norris
    Norris MD; De Graaf D; Haber M; Kavallaris M; Madafiglio J; Gilbert J; Kwan E; Stewart BW; Mechetner EB; Gudkov AV; Roninson IB, 1996, 'Involvement of MDR1 P-Glycoprotein in multifactorial resistance to methotrexate', International Journal of Cancer, vol. 65, pp. 613 - 619, http://dx.doi.org/10.1002/(SICI)1097-0215(19960301)65:5<613::AID-IJC10>3.0.CO;2-8
    Journal articles | 1996
    Professor Murray David Norris
    Norris MD; Bordow SB; Marshall GM; Haber PS; Cohn S; Haber M, 1996, 'Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma', New England Journal of Medicine, vol. 334, pp. 231 - 238, http://dx.doi.org/10.1056/NEJM199601253340405
    Journal articles | 1996
    Professor Murray David Norris
    Cheung BB; Hocker JE; Smith SA; Reichert U; Norris MD; Haber M; Stewart BW; Marshall GM, 1996, 'Retinoic acid receptors B and g distinguish retinoid signals for growth inhibition and neuritogenesis in human neuroblastoma cells', Biochemical and Biophysical Research Communications, vol. 229, pp. 349 - 354, http://dx.doi.org/10.1006/bbrc.1996.1804
    Journal articles | 1996
    Professor Murray David Norris
    Norris MD; Bordow SB; Marshall GM; Heber PS; Cohn S; Haber M, 1996, 'Association between high levels of expression of the multidrug resistance-associated protein (MRP) gene and poor outcome in primary human neuroblastoma', New England Journal of Medicine, pp. 231 - 238
    Journal articles | 1996
    Professor Murray David Norris
    Norris MD; Kwan E; Zhu L; Marshall GM; Haber M, 1996, 'Sensitive non radioactive PCR detection of minimal residual leukaemia using TCR(gamma) gene rearrangements', BRITISH JOURNAL OF HAEMATOLOGY, vol. 93, pp. 225 - 225, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996UP11400225&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1995
    Professor Murray David Norris
    Haber M; Burkhart CA; Regl DL; Madafiglio J; Norris MD; Horwitz SB, 1995, 'Altered expression of Mβ2, the class II β-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance', Journal of Biological Chemistry, vol. 270, pp. 31269 - 31275, http://dx.doi.org/10.1074/jbc.270.52.31269
    Journal articles | 1995
    Professor Murray David Norris
    Haber M; Norris MD; Kavallaris M; Camacho M; Madafiglio J; Baker C; White L; Stewart BW, 1995, 'An assay for the determination of reduced methotrexate accumulation in cells displaying limited viability in vitro', Cancer Letters, vol. 97, pp. 49 - 55, http://dx.doi.org/10.1016/0304-3835(95)03950-2
    Journal articles | 1995
    Professor Murray David Norris
    Norris MD; Kwan EN; Haber M; Marshall GM, 1995, 'Detection of evolving immunoglobin heavy chain gene rearrangements in acute lymphoblastic leukemia: a PCR-based assay employing overlapping DHh primers', Leukemia, vol. 9, pp. 1779 - 1782
    Journal articles | 1995
    Professor Murray David Norris
    Norris MD; Gilbert J; Madafiglio J; Haber M, 1995, 'Analysis of a novel cDNA encoding a C219-reactive peptide isolated from methotrexate-selected multidrug-resistant human leukemic cells', Gene, vol. 156, pp. 313 - 314, http://dx.doi.org/10.1016/0378-1119(94)00541-Y
    Journal articles | 1995
    Professor Murray David Norris
    Marshall GM; Kwan EN; Haber M; Brisco MJ; Sykes PJ; Morley A; Toogood I; Waters K; Tauro G; Ekert H; Norris MD, 1995, 'Characterisation of clonal immunoglobulin heavy chain and T-cell receptor y gene rearrangements during progression of childhood acute lymphoblastic leukemia', Leukemia, vol. 9, pp. 1847 - 1850
    Journal articles | 1995
    Professor Murray David Norris
    Marshall GM; Cheung BB; Stacey KP; Camacho M; Simpson AM; Kwan EN; Smith S; Haber M; Norris MD, 1995, 'Increased retinoic acid receptor gamma expression suppresses the malignant phenotype and alters the differentiation potential of human neuroblastoma cells', Oncogene, vol. 11, pp. 485 - 491
    Journal articles | 1994
    Professor Murray David Norris
    Haber M; Madafiglio J; Bordow SB; Gilbert J; Cheung B; Marshall GM; Norris MD, 1994, 'Expression of retinoic acid-responsive genes in primary neuroblastomas.', Progress in clinical and biological research, vol. 385, pp. 245 - 251
    Journal articles | 1994
    Professor Murray David Norris
    Norris MD; Haber M; Gilbert J; Kavallaris M; Marshall GM; Stewart BW, 1994, 'N-myc gene amplification in neuroblastoma determined by the polymerase chain reaction.', Progress in clinical and biological research, vol. 385, pp. 27 - 33
    Journal articles | 1994
    Professor Murray David Norris
    Bordow SB; Haber M; Madaflglio J; Cheung B; Marshall GM; Norris MD, 1994, 'Expression of the Multidrug Resistance-associated Protein (MRP) Gene Correlates with Amplification and Overexpression of the N-myc Oncogene in Childhood Neuroblastoma', Cancer Research, vol. 54, pp. 5036 - 5040
    Journal articles | 1994
    Professor Murray David Norris
    MARSHALL GM; CHEUNG B; STACEY KP; NORRIS MD; HABER M, 1994, 'REGULATION OF RETINOIC ACID RECEPTOR-ALPHA EXPRESSION IN HUMAN NEUROBLASTOMA CELL-LINES AND TUMOR-TISSUE', ANTICANCER RESEARCH, vol. 14, pp. 437 - 441, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NR46300017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1994
    Professor Murray David Norris
    Marshall GM; Cheung B; Stacey KP; Norris MD; Haber M, 1994, 'Regulation of retinoic acid receptor alpha expression in human neuroblastoma cell lines and tumor tissue', Anticancer Research, vol. 14, pp. 437 - 441
    Journal articles | 1993
    Professor Murray David Norris
    Kavallaris M; Madafiglio J; Norris MD; Haber M, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, vol. 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013
    Journal articles | 1993
    Professor Murray David Norris
    Selig RA; Madafiglio J; Haber M; Norris MD; White L; Stewart BW, 1993, 'Ferritin production and desferrioxamine cytotoxicity in human neuroblastoma cell lines', Anticancer Research, vol. 13, pp. 721 - 725
    Journal articles | 1993
    Professor Murray David Norris
    Haber M; Madafiglio J; Norris MD, 1993, 'Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine', Journal of Cancer Research and Clinical Oncology, vol. 119, pp. 315 - 317, http://dx.doi.org/10.1007/BF01208836
    Journal articles | 1993
    Professor Murray David Norris
    Gilbert J; Norris MD; Haber M; Kavallaris M; Marshall GM; Stewart BW, 1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, vol. 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033
    Journal articles | 1992
    Professor Murray David Norris
    TELFORD DJ; KAVALLARIS M; WHITE L; NORRIS MD; BRIAN MJ; STEWART BW, 1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, vol. 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x
    Journal articles | 1991
    Professor Murray David Norris
    Norris MD; Haber M; Kavallaris M; Brian MJ; Lutze LH; White L; Stewart BW, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, vol. 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W
    Journal articles | 1991
    Professor Murray David Norris
    Stewart BW; Kavallaris M; Catchpoole D; Norris MD, 1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, vol. 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B
    Journal articles | 1991
    Professor Murray David Norris
    Kavallaris M; Haber M; Norris MD; Matherly LH; Stewart BW, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, vol. 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119
    Journal articles | 1990
    Professor Murray David Norris
    White L; Norris MD; Marshall GM; Stewart BW; Tobias V; Sosula L; Trickett A, 1990, 'Heterotransplantation of Human Lymphoid Neoplasms Using a Nude Mouse Intraocular Xenograft Model', Cancer Research, vol. 50, pp. 3078 - 3086
    Journal articles | 1990
    Professor Murray David Norris
    Kavallaris M; Haber M; Norris MD; Pittman SM; Reed C; Stewart BW, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, vol. 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4
    Journal articles | 1989
    Professor Murray David Norris
    Haber M; Norris MD; Kavallaris M; White L; Stewart BW; Bell DR; Davey RA, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, vol. 49, pp. 5281 - 5287
    Journal articles | 1989
    Professor Murray David Norris
    White L; Haber M; Brian MJ; Norris MD; Trickett A; Sosula L; Tiley C; Stewart BW, 1989, 'Therapy‐induced drug resistance in a human leukemia line (LALW‐2)', Cancer, vol. 63, pp. 2103 - 2110, http://dx.doi.org/10.1002/1097-0142(19890601)63:11<2103::AID-CNCR2820631106>3.0.CO;2-N
    Journal articles | 1989
    Professor Murray David Norris
    Haber M; Reed C; Kavallaris M; Norris MD; Stewart BW, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, vol. 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250
    Journal articles | 1989
    Professor Murray David Norris
    Norris MD; Haber M; King M; Davey RA, 1989, 'Atypical multidrug resistance in CCRF-CEM cells selected for high level methotrexate resistance: Reactivity to monoclonal antibody C219 in the absence of P-glycoprotein expression', Biochemical and Biophysical Research Communications, vol. 165, pp. 1435 - 1441, http://dx.doi.org/10.1016/0006-291X(89)92764-2
    Journal articles | 1988
    Professor Murray David Norris
    Seshadri R; Matthews C; Norris MD; Brian MJ, 1988, 'N-myc amplified in retinoblastoma cell line FMC-RB1', Cancer Genetics and Cytogenetics, vol. 33, pp. 25 - 27, http://dx.doi.org/10.1016/0165-4608(88)90045-3
    Journal articles | 1988
    Professor Murray David Norris
    Norris MD; Stewart BW, 1988, 'Sizing of single-stranded regions in double-stranded DNA by preparative benzoylated DEAE-cellulose chromatography', FEBS Letters, vol. 228, pp. 223 - 227, http://dx.doi.org/10.1016/0014-5793(88)80003-6
    Journal articles | 1988
    Professor Murray David Norris
    Norris MD; Brian MJ; Vowels MR; Stewart BW, 1988, 'N-myc amplification in Wilms' tumor', Cancer Genetics and Cytogenetics, vol. 30, pp. 187 - 189, http://dx.doi.org/10.1016/0165-4608(88)90112-4
    Journal articles | 1985
    Professor Murray David Norris
    Ward EJ; Haber M; Norris MD; Stewart BW, 1985, 'Single-Strand-Specific Degradation of DNA during Isolation of Rat Liver Nuclei†', Biochemistry, vol. 24, pp. 5803 - 5809, http://dx.doi.org/10.1021/bi00342a018
  • Conference Papers | 2021
    Professor Murray David Norris
    Vijayasubhash V, 2021, 'Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR', in Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR, presented at AACR 2021, http://dx.doi.org/10.1158/1538-7445.AM2021-639
    Conference Abstracts | 2020
    Professor Murray David Norris
    Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292, http://dx.doi.org/10.1093/neuonc/noaa222.076
    Conference Abstracts | 2020
    Professor Murray David Norris
    Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.065
    Conference Abstracts | 2020
    Professor Murray David Norris
    Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-SY09-02
    Conference Abstracts | 2020
    Professor Murray David Norris
    Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'DIPG-16. COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii290 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.066
    Conference Abstracts | 2020
    Professor Murray David Norris
    Atkinson C; Tactacan C; Kamili A; Saletta F; Gana C; Eden G; Mayoh C; Lock R; Norris M; Haber M; Gifford A; Trahair T; Fletcher J, 2020, 'Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a35
    Conference Abstracts | 2020
    Professor Murray David Norris
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a52
    Conference Abstracts | 2019
    Professor Murray David Norris
    Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Montreal, CANADA, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, Montreal, CANADA, 17 September 2019 - 20 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Professor Murray David Norris
    Nagy Z; Kanikevich M; Koach J; Mayoh C; Carter D; Liu T; Du Y; Jiang C; Haber M; Norris M; Cheung B; Marshall G, 2019, 'Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3659
    Conference Abstracts | 2019
    Professor Murray David Norris
    Nagy Z; Kanikevichi M; Koachi J; Mayoh C; Carter D; Liu T; Du Y; Jiang C; Haber M; Norris M; Cheung B; Marshall G, 2019, 'Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3659
    Conference Papers | 2019
    Professor Murray David Norris
    Valli E; Xue C; Cheung L; Gamble L; Pandher R; Di Giacomo S; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2616
    Conference Abstracts | 2019
    Professor Murray David Norris
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Abstract 2884: Establishment of patient-derived xenograft models for high-risk neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2884
    Conference Abstracts | 2019
    Professor Murray David Norris
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Abstract 4741: Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.am2019-4741
    Conference Papers | 2019
    Professor Murray David Norris
    Valli E; Xue C; Cheung L; Gamble L; Pandher R; Giacomo SD; Burkhart C; Fedtsova N; Ferrucci F; Makarov S; Telfer T; Codd R; Scott D; Perini G; Osterman A; Gudkov A; Norris M; Haber M, 2019, 'Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2616
    Conference Papers | 2019
    Professor Murray David Norris
    Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3809
    Conference Papers | 2019
    Professor Murray David Norris
    Hanssen KM; Gana CC; Wheatley MS; Yu DM; Flemming CL; Young R; Wright GM; Conseil G; Kennedy CJ; deFazio A; Solomon B; Cole SP; Norris MD; Haber M; Fletcher JI, 2019, 'Abstract 3809: Modulation of MRP1 activity reverses chemotherapy resistance in adult cancer cells', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.am2019-3809
    Conference Abstracts | 2019
    Professor Murray David Norris
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-4741
    Conference Abstracts | 2019
    Professor Murray David Norris
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Establishment of patient-derived xenograft models for high-risk neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2884
    Conference Papers | 2018
    Professor Murray David Norris
    Tee AE; Liu PY; Milazzo G; Hannan KM; Maag J; Bartonicek N; Song R; Jiang CC; Zhang XD; Norris MD; Haber M; Marshall GM; Li J; Vandesompele J; Mattick JS; Mestdagh P; Perini G; Hannan RD; Dinger ME; Liu T, 2018, 'Eradication of neuroblastoma by suppressing the expression of a single noncoding RNA', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2453
    Conference Abstracts | 2018
    Professor Murray David Norris
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i49 - i49, http://dx.doi.org/10.1093/neuonc/noy059.095
    Conference Abstracts | 2017
    Professor Murray David Norris
    Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
    Conference Abstracts | 2017
    Professor Murray David Norris
    Franshaw L; Tsoli M; Byrne J; Sivarajasingam S; Norris M; Marshall G; Ziegler D, 2017, 'TRTH-05. PREDICTORS OF SUCCESS OF PHASE 2 PAEDIATRIC ONCOLOGY CLINICAL TRIALS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv52 - iv52, http://dx.doi.org/10.1093/neuonc/nox083.217
    Conference Papers | 2017
    Professor Murray David Norris
    Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'Abstract 2006: AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-2006
    Conference Papers | 2017
    Professor Murray David Norris
    Flynn AT; Vu A; Liu K; Scadden E; Attiyeh E; Norris M; Haber M; Hogarty M, 2017, 'Abstract 4883: Targeting tumor-amplifiedODC1with difluoromethylornithine (DFMO) inhibits global protein translation and has antitumor activity in neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-4883
    Conference Papers | 2017
    Professor Murray David Norris
    Gana CC; Hanssen K; Yu DM; Flemming C; Norris M; Haber M; Fletcher J, 2017, 'A modulator of multidrug resistance protein 1 selectively depletes glutathione and synergizes with L-buthionine sulfoximine to sensitize MRP1-expressing cancer cells to chemotherapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-4056
    Conference Papers | 2017
    Professor Murray David Norris
    Gao J; Somers K; Hannan KM; Fletcher JI; Liu B; Hannan RD; Pearson RB; Haber M; Norris MD; Henderson MJ, 2017, 'Abstract 1956: ABCE1 regulates the translational profile of neuroblastoma to drive tumor progression', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-1956
    Conference Papers | 2017
    Professor Murray David Norris
    Somers K; Middlemiss S; Biktasova A; Karsa M; Cheung L; Kosciolek A; Evans K; Mayoh C; Kees UR; Korotchkina L; Chernova OB; Lock RB; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2017, 'Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-1175
    Conference Abstracts | 2016
    Professor Murray David Norris
    Sutton R; Law T; Venn NC; Wadham C; Mould EVA; Norris MD; Kotecha RS; Marschalek R; Meyer C; Dalla-Pozza L; Marshall GM; Lock RB; Trahair TN, 2016, 'Comparison of MRD Levels and Gene Expression Patterns in MLL-R Versus Non-MLL Infant ALL', in BLOOD, AMER SOC HEMATOLOGY, San Diego, CA, Vol. 128, presented at 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA, 03 December 2016 - 06 December 2016, http://dx.doi.org/10.1182/blood.V128.22.1740.1740
    Conference Papers | 2016
    Professor Murray David Norris
    Xue C; Yu DM; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Russell A; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA, http://dx.doi.org/10.1158/1538-7445.am2016-2450
    Conference Papers | 2016
    Professor Murray David Norris
    Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Duong HTT; Boyer C; Flemming C; Yee EMH; Kumar N; Parmar A; Pascali G; Charil A; Haber M; Norris M; Kavallaris M, 2016, 'Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, New Orleans, LA, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), New Orleans, LA, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1340
    Conference Papers | 2016
    Professor Murray David Norris
    Gonzales-Aloy E; Norris MD; Wang JY, 2016, 'Abstract 1917: Suppression of miR-101a contributes to leukemogenesis by regulating epigenetic and pro-survival pathways in MLL AML stem cells', in Molecular and Cellular Biology, Genetics, American Association for Cancer Research, presented at Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA, http://dx.doi.org/10.1158/1538-7445.am2016-1917
    Conference Papers | 2016
    Professor Murray David Norris
    Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2016, 'Abstract 51: Molecular profiling of relapsed childhood cancer', in Other Topics, American Association for Cancer Research, presented at Abstracts: AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy; June 13-16, 2015; Salt Lake City, UT, http://dx.doi.org/10.1158/1557-3265.pmsclingen15-51
    Conference Papers | 2015
    Professor Murray David Norris
    Koach J; Liu B; Bell JL; Huettelmaier S; Liu T; Carter DR; Haber M; Norris MD; Fletcher J; Cheung BB; Marshall GM, 2015, 'PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-962
    Conference Abstracts | 2015
    Professor Murray David Norris
    Chudakova D; Somers K; Middlemiss S; Wen V; Kwek A; Liu B; Clifton M; Pan S; Cruikshank S; Scandlyn M; Failes T; Hoang W; Kees U; Chernova O; Gudkov AV; Haber M; Norris M; Henderson M, 2015, 'Selective and rapid killing of mixed lineage leukemia and CALM-AF10 leukemia by SM7, a novel small molecule identified by chemical library screening', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Fort Lauderdale, FL, Vol. 76, presented at AACR Special Conference on Advances in Pediatric Cancer Research - From Mechanisms and Models to Treatment and Survivorship, Fort Lauderdale, FL, 09 November 2015 - 12 November 2015, http://dx.doi.org/10.1158/1538-7445.PEDCA15-B23
    Conference Papers | 2015
    Professor Murray David Norris
    Kao FCL; Failes T; Arndt GM; Norris M; Kavallaris M, 2015, 'Discovery of a small molecule TUBB3/beta III-tubulin modulator in lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-3660
    Conference Abstracts | 2015
    Professor Murray David Norris
    Tee AE; Liu P; Maag J; Song R; Li J; Cheung BB; Haber M; Norris MD; Marshall GM; Dinger M; Liu T, 2015, 'The long noncoding RNA MALAT1 promotes hypoxia-driven angiogenesis by upregulating pro-angiogenic gene expression in neuroblastoma cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-146
    Conference Papers | 2015
    Professor Murray David Norris
    Williams R; Russell A; Bongers A; Sagnella S; Fife C; Jessup W; DeFazio A; Chenevix-Trench G; Haber M; Norris M; Henderson M, 2015, 'Abstract 313: Examining the role of ABCA1 cholesterol transporter in ovarian cancer spheroids', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2015-313
    Conference Abstracts | 2015
    Professor Murray David Norris
    Sartor M; Barbaric D; Law T; Dissanayake A; Venn NC; Karsa M; Wong SWJ; Norris MD; Revesz T; Ritchie P; Shaw PJ; Bradstock KF; Pozza LD; Trahair TN; Sutton R, 2015, 'Improved Concordance of Minimal Residual Disease Measurements By Quantitative PCR and 10-Color Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, Vol. 126, presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor Murray David Norris
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Henderson MJ; Middlemass S; Carter D; Tsoli M; Ehteda A; Simon S; Oberthuer A; Fischer M; Gurova K; Burkhart C; Purmal A; Lock RB; Ziegler D; Marshall GM; Gudkov AV; Norris MD, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1611
    Conference Papers | 2015
    Professor Murray David Norris
    O'Brien R; Maritz MF; Kong CF; Purgato S; Liu B; Yang C; Russell A; Murray J; Flemming C; Haber M; Perini G; Norris MD; Fletcher JI; Mackenzie KL, 2015, 'Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2015-488
    Conference Presentations | 2014
    Professor Murray David Norris
    Shahbazi J; Scarlett CJ; Norris M; Liu B; Haber M; Tee AE; Carrier A; Biankin AV; London WB; Marshall GM; Lock R; Liu T, 2014, 'Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1', Vol. 74, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-5138
    Conference Papers | 2014
    Professor Murray David Norris
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, European Org Res & Treatment Canc, Barcelona, SPAIN, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, European Org Res & Treatment Canc, Barcelona, SPAIN, 18 November 2014 - 21 November 2014, http://dx.doi.org/10.1016/S0959-8049(14)70548-9
    Conference Papers | 2014
    Professor Murray David Norris
    Dietrich PA; Norris MD; Wang JY, 2014, 'GNA13, a Novel Component of the GPR84/Beta-Catenin Signaling Axis in AML Stem Cells, Regulates the Maintenance of MLLAF9 Leukemogenesis', in BLOOD, AMER SOC HEMATOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349242705068&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Professor Murray David Norris
    Carter DR; Cheung BB; Liu T; Liu C; Norris MD; Haber M; Murray J; Gurova KV; Gudkov AV; Marshall GM, 2013, 'The facilitates chromatin transcription (FACT) protein complex promotes neuroblastoma tumor initiation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-5043
    Conference Papers | 2013
    Professor Murray David Norris
    Haber M; Murray J; Carnegie-Clark A; Webber H; Marshall GM; Gurova KV; Burkhart CA; Purmai A; Gudkov AV; Norris MD, 2013, 'Anticancer compound curaxin CBL0137, that simultaneously suppresses NF-kappa B and activates p53, is highly effective in two independent mouse models of neuroblastoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-2759
    Conference Papers | 2013
    Professor Murray David Norris
    Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3808
    Conference Papers | 2012
    Professor Murray David Norris
    Huynh T; Tivnan A; Munoz M; Cheung L; Vishvanath A; Flemming C; Watt F; Burkhart C; Gudkov A; Fletcher J; Henderson M; Norris M; Haber M, 2012, 'Abstract 1834: Targeting ABC transporters in cancer through small molecule inhibitors', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL, http://dx.doi.org/10.1158/1538-7445.am2012-1834
    Conference Papers | 2012
    Professor Murray David Norris
    Norris MD; Fletcher JI; Gherardi S; Murray J; Burkhart C; Russell A; Valli E; Oberthuer A; Ashton LJ; London WB; Marshall GM; Perini G; Haber M, 2012, 'GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-789
    Conference Abstracts | 2011
    Professor Murray David Norris
    Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; MacKenzie KL; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-3027
    Conference Papers | 2011
    Professor Murray David Norris
    Norris MD; Henderson MJ; Porro A; Munoz M; Iraci N; Xue C; Murray J; Flemming C; Fletcher J; Gherardi S; Kwek A; Russell A; London WB; Buxton AB; Ashton L; Sartorelli AC; Cohn SL; Schwab M; Marshall GM; Perini G; Haber M, 2011, 'ABCC/MRP multidrug transporters contribute to neuroblastoma biology, pathogenesis and clinical outcome, independently of any role in cytotoxic drug efflux', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-954
    Conference Papers | 2011
    Professor Murray David Norris
    Xue C; Cheung L; Norris MD; Haber M; Burkhart C; Fedtsova N; Gudkov A; Makarov SS, 2011, 'Abstract 617: Small molecule that simultaneously inhibits Myc oncoprotein and activates HIF1A', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.am2011-617
    Conference Papers | 2011
    Professor Murray David Norris
    Lau DT; Norris MD; Marshall GM; Haber M; Ashton LJ, 2011, 'New evidence supports the potential use of methotrexate in children with MYCN-amplified neuroblastoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-LB-367
    Conference Papers | 2011
    Professor Murray David Norris
    Henderson MJ; Hedditch EL; Russell AJ; deFazio A; Emmanuel C; George J; Chenevix-Trench G; Bowtell D; Norris MD; Haber M, 2011, 'Abstract 1660: Cholesterol efflux transporter gene expression predicts clinical outcome in serous ovarian cancer', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL, http://dx.doi.org/10.1158/1538-7445.am2011-1660
    Conference Papers | 2010
    Professor Murray David Norris
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair T; Scarlett C; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Stossi F; Katzenellenbogen BS; Biankin AV; Perini G; Liu T, 2010, 'Abstract 4869: Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', in Cellular and Molecular Biology, American Association for Cancer Research, presented at Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am10-4869
    Conference Papers | 2010
    Professor Murray David Norris
    Lau DT; Murray J; Norris M; Marshall GM; Haber M; Ashton LJ, 2010, 'Abstract 888: Reduced folate carrier gene polymorphism (RFC 80G>A): Associations with clinical outcome in NMYC amplified neuroblastoma patients', in Epidemiology, American Association for Cancer Research, presented at Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am10-888
    Conference Papers | 2008
    Professor Murray David Norris
    Haber M; Cheng N; Smith J; Murray J; Hogarty MD; London WB; Marshall GM; Norris MD, 2008, 'Overexpression of ODC1 is associated with poor outcome in childhood neuroblastoma and represents an important therapeutic target', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2008-5832
    Conference Papers | 2008
    Professor Murray David Norris
    Bell JL; Cheung BB; D'Andreti C; Koach J; Raif A; Thomas WD; Norris M; Haber M; Kavallaris M; Marshall GM, 2008, 'The role of the estrogen-responsive B box protein (EBBP) in cancer cell cycle progression', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Lyon, FRANCE, pp. 95 - 95, presented at 20th Meeting of the European-Association-for-Cancer-Research, Lyon, FRANCE, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71542-8
    Conference Abstracts | 2008
    Professor Murray David Norris
    Sutton R; Venn NC; Kilo T; Bhadri V; Pozza LD; Marshall GM; Haber M; Norris MD; Shaw P, 2008, 'The value of monitoring for minimal residual disease post-transplant in children with acute lymphoblastic leukaemia', in British Journal of Haematology, Blackwell Publishing Ltd, Oxford, England, Vol. 141, pp. 102 - 102, presented at Abstracts of the British Society of Haematology 48th Annual Scientific Meeting, incorporating the 6th Bi-Annual I-BFM Leukaemia Symposium, Glasgow, SCOTLAND, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255032500279&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2007
    Professor Murray David Norris
    Norris MD; Smith J; Kwek A; Flemming C; Cohn SL; London WB; Buxton A; Marshall GM; Haber M, 2007, 'Expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3, and ABCC4/MRP4 are powerful predictors of clinical outcome in childhood neuroblastoma', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000455043702481&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2006
    Professor Murray David Norris
    Choi S; Kwan E; Beesley A; Sutton R; Lock RB; Papa R; Marshall GM; Kees UR; Haber M; Norris MD, 2006, 'Relapse in children with acute lymphoblastic leukaemia is associated with selection of a pre-existing drug resistance subclone', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 81 - 81, http://dx.doi.org/10.1016/S1359-6349(06)70257-9
    Conference Papers | 2006
    Professor Murray David Norris
    Ashton LJ; Murray JE; Marshall GM; Haber M; Ashley DM; Norris MD, 2006, 'Polymorphisms of glutathione-S-transferase and N-acetyltransferase genes and response to treatment in childhood neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606202297&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Professor Murray David Norris
    Burkhart CA; Watt F; Pajic M; Murray J; Xue C; Flemming C; Smith J; Marshall GM; Haber M; Norris MD; Gudkov AV, 2006, 'Selective Sensitization of murine tumors to chemotherapy by a novel class of non-toxic small molecule inhibitors of MRP1', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606201252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2003
    Professor Murray David Norris
    Laughton SJ; Ashton LJ; Kwan E; Norris MD; Haber M; Marshall GM, 2003, 'Early markers of the therapeutic index in children with acute lymphoblastic leukaemia predict outcome.', in BLOOD, AMER SOC HEMATOLOGY, SAN DIEGO, CALIFORNIA, pp. 879A - 879A, presented at 45th Annual Meeting of the American-Society-of-Hematology, SAN DIEGO, CALIFORNIA, 06 December 2003 - 09 December 2003, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186536703271&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Professor Murray David Norris
    Verrills N; Flemming C; Liu M; Ivery M; Norris MD; Haber M; Kavallaris M, 2002, 'Acquired beta-tubulin mutations affecting microtubule stability and drug binding', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 463A - 463A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102604&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2001
    Professor Murray David Norris
    Lock RB; Liem N; Tajbakhsh M; Milross CG; Xue CY; Haber M; Norris MD; Marshall GM; Rice AM, 2001, 'Novel biological characteristics and disparate vincristine responses of primary childhood acute lymphoblastic leukemia cells engrafted into non-obese diabetic/severe combined immunodeficient mice.', in BLOOD, AMER SOC HEMATOLOGY, pp. 309A - 310A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172134101312&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Professor Murray David Norris
    Haber PS; Norton ID; Norris MD; Apte MV; Pirola RC; Roberts I; Wilson JS, 1999, 'Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis?', in Gastroenterology, W B Saunders Co, Philadelphia, PA, USA, pp. 114 A466, presented at Digestive Disease Week and the 99th Annual Meeting of the American Gastroenterological Association, New Orleans, Louisiana, USA, 17 May 1999 - 20 May 1999, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000073089601884&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Awards

2011            Invited speaker, Minimal Residual Disease and Targeted Therapy in Children with ALL and neuroblastoma The Institute of Cancer Research / The Royal Marsden Hospital, Sutton, UK

2011            Invited Speaker, 70th Annual Meeting of the Japanese Cancer Conference, Nagoya, Japan “Targeting multidrug transporters in neuroblastoma”

2012            Invited Speaker, 3rd FEBS Special Meeting on ABC Proteins, Innsbruck, Austria 2012, “Targeting ABC transporters in childhood cancer”

2012            Cancer Institute NSW Premier’s Award for Translational Cancer Research

2012            NHMRC Program Grant was recognised in the “10 of the Best” Research Projects 2012

2014            Invited Speaker, 2014 International Academy of Pathology Meeting, Bangkok, Thailand

2014-2016   Elected Incoming President, Advances in Neuroblastoma Research Association

2015            Appointed a Member (AM) of the Order of Australia, for significant service to medical research as a molecular biologist and through pioneering development of treatments for cancer in children

2015            Shortlisted as a Finalist for The Australian Innovation Challenge Award, pioneering work in improving the survival rates of children with acute lymphoblastic leukaemia

2016-2018    President, Advances in Neuroblastoma Research Association

2019            Inaugural Sally Crossing Award for an Outstanding Outcome in Cancer Research, for his development of a new treatment approach for acute lymphoblastic leukeamia – doubling survival rates to over 70% today ($50,000)

2019-2020            Member, National Steering Committee, National Drug Discovery Centre, Walter and Eliza Hall Institute, Melbourne, VIC

Grants

2021-2024   NHMRC Childhood Cancer Research (MRFF)
'Improving outcomes for children with high risk cancer'

2020-2023   Cancer Australia PdCCRS APP1188234/The Kids Cancer Project
'Enhanced polyamine depletion as a novel therapy for aggressive childhood cancers'

2020-2023   Australian Cancer Research Foundation
'The ACRF Child Cancer Liquid Biopsy Program'

2019-2021   Cancer Australia
'Targeting the NAD pathway as a new therapeutic strategy for high-risk leukaemia in children')

2019            Tour de Cure Foundation
A personalised medicine approach to the treatment of acute myeloid leukaemia in children
'

2018-2020   NHMRC Development Grant
'Multidrug Resistance Protein 1 inhibitors to sensitise cancers to chemotherapy'

2018-2022   NHMRC Program Grant
'More effective therapeutic targeting of high-risk childhood cancer: Neuroblastoma as a model'

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