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Dr Nady Braidy

Dr Nady Braidy

Senior Research Fellow
Medicine & Health
Centre for Healthy Brain Ageing

Research Interests

Dementia is one of the top five causes of death in Australia with an increasing incidence due to an aging population. Significant evidence points to oxidative stress (OS) as a major underlying factor in brain cell degeneration. Unfortunately, it is not known at what stage of life this OS begins in humans or what behaviours influence OS in the human brain. As OS underlies brain cell degeneration and the development of dementia, my current work will help to answer these questions and contribute to the development of strategies that will help maintain and improve brain and cellular function into older age.

ILP Research Interests (Will supervise ILP students)

Chemical And Drugs; Diseases And Disorders Life Sciences Psychiatric Disorders; 

Laboratory based teaching

PhD, Master and Honour students

Society Memberships & Professional Activities

American Alzheimer's Association; International College for Geriatric Psychoneuropharmacology (ICGP); Member of the Australian Society for Medical Research (ASMR); Member of the Australian Neuroscience Society (ANS); International Society for Tryptophan Research (ISTRY); Neurotoxicity Society

Funding Sources

National Health and Medical Research Council; Australian Research Council; Alzheimer's Australia Viertel Foundation; UNSW Faculty of Medicine

Other Postgraduate Research Honours projects

- Plasma biomarkers of ageing

- Plasma lipidome changes associated with ageing and neurodegenerative disease of ageing. In particular, plasma phospholipids and fatty acid associations with ageing, health status (frailty, MCI, APOE allele, etc) and disorders such as MCI and dementia.

- Peripheral blood markers of vascular risk and/or CVD which alone, or in combination with markers of AD, can predict the onset of clinical symptoms and vascular dementia progression

- Promotion of cellular nicotinamide adenine dinucleotide (NAD+) anabolism as a strategy to improve cellular senescence and cognitive function.

- Develop and test a series of novel superparamagnetic iron oxide nanoparticles that can penetrate the blood-brain barrier (BBB) and provide a superparamagnetic signal for amyloid imaging using MRI with limited toxicity.

- In vitro and in vivo studies on polyphenols as an integral strategy in preventing and treating diseases associated with neurodegeneration.

Meet Our Researcher
Click here to read Dr Nady Braidy's ‘Meet Our Researcher’ interview
Phone
9385 8494
E-mail
n.braidy@unsw.edu.au
  • Books | 2015
    Braidy N, 2015, Pomegranates: Old age remedy for today's diseases
  • Book Chapters | 2023
    Braidy N; Poljak A; Jayasena T; Adams S; Sachdev P, 2023, 'Glutamate in the Pathogenesis of Gliomas', in Handbook of Neurotoxicity, Second Edition, Springer International Publishing, pp. 2029 - 2041, http://dx.doi.org/10.1007/978-3-031-15080-7_149
    Book Chapters | 2023
    Braidy N; Poljak A; Jayasena T; Guillemin GJ; Sachdev P, 2023, 'Ionotropic Receptors in the Central Nervous System and Neurodegenerative Disease', in Handbook of Neurotoxicity, Second Edition, Springer International Publishing, pp. 747 - 768, http://dx.doi.org/10.1007/978-3-031-15080-7_126
    Book Chapters | 2023
    Braidy N; Sachdev PS, 2023, 'Chapter 8 Pharmacology of NAD+ boosters', in Anti-Aging Pharmacology, Elsevier, pp. 177 - 192, http://dx.doi.org/10.1016/b978-0-12-823679-6.00005-9
    Book Chapters | 2023
    Essa MM; Braidy N; Subash S; Vijayan RK; Guillemin GJ, 2023, 'Excitotoxicity in the Pathogenesis of Autism', in Handbook of Neurotoxicity, Second Edition, Springer International Publishing, pp. 1949 - 1954, http://dx.doi.org/10.1007/978-3-031-15080-7_148
    Book Chapters | 2023
    Helman T; Braidy N, 2023, 'NAD+ as a Target for Cancer Treatment', in Handbook of Cancer and Immunology, Springer International Publishing, pp. 1 - 27, http://dx.doi.org/10.1007/978-3-030-80962-1_269-1
    Book Chapters | 2022
    Braidy N; Poljak A; Jayasena T; Adams S; Sachdev P, 2022, 'Glutamate in the Pathogenesis of Gliomas', in Handbook of Neurotoxicity, Springer International Publishing, pp. 1 - 13, http://dx.doi.org/10.1007/978-3-030-71519-9_149-1
    Book Chapters | 2022
    Braidy N; Poljak A; Jayasena T; Guillemin GJ; Sachdev P, 2022, 'Ionotropic Receptors in the Central Nervous System and Neurodegenerative Disease', in Handbook of Neurotoxicity, Springer International Publishing, pp. 1 - 22, http://dx.doi.org/10.1007/978-3-030-71519-9_126-1
    Book Chapters | 2022
    Braidy N; Sachdev PS, 2022, 'Pharmacology of NAD+ boosters', in Anti-Aging Pharmacology, pp. 177 - 192, http://dx.doi.org/10.1016/B978-0-12-823679-6.00005-9
    Book Chapters | 2022
    Essa MM; Braidy N; Subash S; Vijayan RK; Guillemin GJ, 2022, 'Excitotoxicity in the Pathogenesis of Autism', in Handbook of Neurotoxicity, Springer International Publishing, pp. 1 - 5, http://dx.doi.org/10.1007/978-3-030-71519-9_148-1
    Book Chapters | 2021
    Braidy N; Poljak A; Sachdev P, 2021, 'Nicotinamide Adenine Dinucleotide (NAD+) in Aging', in Encyclopedia of Gerontology and Population Aging, Springer International Publishing, pp. 3496 - 3505, http://dx.doi.org/10.1007/978-3-030-22009-9_1035
    Book Chapters | 2021
    Braidy N; Villalva M, 2021, 'NAD+: A crucial regulator of sirtuin activity in aging', in Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease, Elsevier, pp. 23 - 35, http://dx.doi.org/10.1016/B978-0-12-814118-2.00008-2
    Book Chapters | 2020
    Braidy N, 2020, 'Modulators of Nrf2 Activation During Inflammation', in Progress in Inflammation Research, Springer International Publishing, pp. 189 - 205, http://dx.doi.org/10.1007/978-3-030-44599-7_8
    Book Chapters | 2020
    Jayasena T; Bustamante S; Clement J; Welschinger R; Caplan GA; Sachdev PS; Braidy N, 2020, 'Clinical Assessment of the NADome as Biomarkers for Healthy Aging', in Guest PC (ed.), Clinical and Preclinical Models for Maximizing Healthspan Methods and Protocols, Humana, pp. 207 - 216, http://dx.doi.org/10.1007/978-1-0716-0471-7_13
    Book Chapters | 2020
    Poljak A; Braidy N; Wong M; Liu Y; Hosseini M; Sachdev P, 2020, 'Lipids, brain ageing, dementia, and lipidomics', in Martin CR; Preedy VR (ed.), Diagnosis and Management in Dementia The Neuroscience of Dementia, Volume 1, Academic Press, pp. 183 - 205, http://dx.doi.org/10.1016/B978-0-12-815854-8.00012-4
    Book Chapters | 2019
    Braidy N; Poljak A; Sachdev P, 2019, 'Nicotinamide Adenine Dinucleotide (NAD+) in Aging', in Danan G; Dupre ME (ed.), Encyclopedia of Gerontology and Population Aging, Springer International Publishing, Cham, Switzerland, pp. 1 - 1, http://dx.doi.org/10.1007/978-3-319-69892-2_1035-1
    Book Chapters | 2018
    Schultz MB; Lu Y; Braidy N; Sinclair DA, 2018, 'Assays for NAD+-Dependent reactions and NAD+ metabolites', in Chang P (ed.), ADP-ribosylation and NAD+ Utilizing Enzymes. Methods in Molecular Biology, Humana Press, New York, N.Y., pp. 77 - 90, http://dx.doi.org/10.1007/978-1-4939-8588-3_6
    Book Chapters | 2017
    Braidy N; Poljak A; Jayasena T; Sachdev PS, 2017, 'Natural Plant-Derived Acetylcholinesterase Inhibitors: Relevance for Alzheimer's Disease', in Andrade PB; Valentao P; Pereira DM (ed.), Natural Products Targeting Clinically Relevant Enzymes, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pp. 297 - 318, http://dx.doi.org/10.1002/9783527805921.ch12
    Book Chapters | 2014
    Braidy N; Poljak A; Jayasena T; Adams S; Sachdev P, 2014, 'Glutamate in the Pathogenesis of Gliomas', in Kostrzewa RM (ed.), Handbook of Neurotoxicity, Springer, New York, USA, pp. 1287 - 1298, http://dx.doi.org/10.1007/978-1-4614-5836-4_149
    Book Chapters | 2014
    Braidy N; Poljak A; Jayasena T; Guillemin GJ; Sachdev P, 2014, 'Ionotropic receptors in the central nervous system and neurodegenerative disease', in Kostrzewa RM (ed.), Handbook for Neurotoxicity, Springer, New York, USA, pp. 1071 - 1092, http://dx.doi.org/10.1007/978-1-4614-5836-4_126
    Book Chapters | 2014
    Braidy N; Poljak A; Jayasena T; Sachdev P, 2014, 'Drug Treatments for Alzheimer’s Disease: Hopes and Challenges', in Kostrzewa RM (ed.), Handbook for Neurotoxicity, Springer, New York, USA, pp. 1173 - 1190, http://dx.doi.org/10.1007/978-1-4614-5836-4_141
    Book Chapters | 2014
    Essa MM; Braidy N; Subash S; Vijayan RK; Guillemin GJ, 2014, 'Excitotoxicity in the pathogenesis of autism', in Handbook of Neurotoxicity, pp. 1267 - 1271, http://dx.doi.org/10.1007/978-1-4614-5836-4_148
    Book Chapters | 2012
    Marcal H; Wanandy NS; Castellano-Gonzalez G; Braidy N; Guillemin GJ, 2012, 'Curcumin: Medicinal Properties, Molecular Targets and Biological Mechanisms', in Sasaki J; Kichida M (ed.), Curcumin: Biosynthesis, Medicinal Uses and Health Benefits, Nova, pp. 133 - 154, https://www.novapublishers.com/catalog/product_info.php?products_id=30913&osCsid=;%20https://www.novapublishers.com/catalog/product_info.php?products_id=35977
  • Journal articles | 2023
    Braidy N; Brew BJ; Inestrosa NC; Chung R; Sachdev P; Guillemin GJ, 2023, 'Retraction Note to: Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons (Metabolic Brain Disease, (2014), 29, 3, (873-883), 10.1007/s11011-014-9557-9)', Metabolic Brain Disease, 38, pp. 2197, http://dx.doi.org/10.1007/s11011-023-01241-3
    Journal articles | 2023
    Braidy N, 2023, 'Meet the Frontier Section Editor', CNS & Neurological Disorders - Drug Targets, 22, pp. 461 - 461, http://dx.doi.org/10.2174/187152732204230116112705
    Journal articles | 2023
    Dai J; Chan DKY; Chan RO; Hirani V; Xu YH; Braidy N, 2023, 'The association between dietary patterns, plasma lipid profiles, and inflammatory potential in a vascular dementia cohort', Aging Medicine, 6, pp. 155 - 162, http://dx.doi.org/10.1002/agm2.12249
    Journal articles | 2023
    Helman T; Braidy N, 2023, 'Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders', Drugs and Aging, 40, pp. 33 - 48, http://dx.doi.org/10.1007/s40266-022-00989-0
    Journal articles | 2023
    Helman TJ; Headrick JP; Stapelberg NJC; Braidy N, 2023, 'The sex-dependent response to psychosocial stress and ischaemic heart disease', Frontiers in Cardiovascular Medicine, 10, pp. 1072042, http://dx.doi.org/10.3389/fcvm.2023.1072042
    Journal articles | 2023
    Singla RK; De R; Efferth T; Mezzetti B; Sahab Uddin M; Sanusi ; Ntie-Kang F; Wang D; Schultz F; Kharat KR; Devkota HP; Battino M; Sur D; Lordan R; Patnaik SS; Tsagkaris C; Sai CS; Tripathi SK; Găman MA; Ahmed MEO; González-Burgos E; Babiaka SB; Paswan SK; Odimegwu JI; Akram F; Simal-Gandara J; Urquiza MS; Tikhonov A; Mondal H; Singla S; Lonardo SD; Mulholland EJ; Cenanovic M; Maigoro AY; Giampieri F; Lee S; Tzvetkov NT; Louka AM; Verma P; Chopra H; Olea SP; Khan J; Alvarez Suarez JM; Zheng X; Tomczyk M; Sabnani MK; Medina CDV; Khalid GM; Boyina HK; Georgiev MI; Supuran CT; Sobarzo-Sánchez E; Fan TP; Pittala V; Sureda A; Braidy N; Russo GL; Vacca RA; Banach M; Lizard G; Zarrouk A; Hammami S; Orhan IE; Aggarwal BB; Perry G; Miller MJ; Heinrich M; Bishayee A; Kijjoa A; Arkells N; Bredt D; Wink M; Fiebich BL; Kiran G; Yeung AWK; Gupta GK; Santini A; Lucarini M; Durazzo A; El-Demerdash A; Dinkova-Kostova AT; Cifuentes A; Souto EB; Zubair MAM; Badhe P; Echeverría J; Horbańczuk JO; Horbanczuk OK; Sheridan H; Sheshe SM; Witkowska AM; Abu-Reidah IM; Riaz M; Ullah H; Oladipupo AR; Lopez V; Sethiya NK; Shrestha BG; Ravanan P; Gupta SC, 2023, 'The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis', Phytomedicine, 108, pp. 154520, http://dx.doi.org/10.1016/j.phymed.2022.154520
    Journal articles | 2022
    Balducci E; Braidy N; Migaud M, 2022, 'Editorial: NAD+ metabolism as a novel target against infection–Volume II', Frontiers in Molecular Biosciences, 9, pp. 1087897, http://dx.doi.org/10.3389/fmolb.2022.1087897
    Journal articles | 2022
    Braidy N; Cig B; Jiang LH; Shu X, 2022, 'Editorial: The role of astrocyte signalling pathways in ageing-induced neurodegenerative pathologies', Frontiers in Physiology, 13, pp. 1002428, http://dx.doi.org/10.3389/fphys.2022.1002428
    Journal articles | 2022
    Chan DKY; Braidy N; Chen RF; Xu YH; Bentley S; Lubomski M; Davis RL; Chen J; Sue CM; Mellick GD, 2022, 'Strong Predictive Algorithm of Pathogenesis-Based Biomarkers Improves Parkinson’s Disease Diagnosis', Molecular Neurobiology, 59, pp. 1476 - 1485, http://dx.doi.org/10.1007/s12035-021-02604-6
    Journal articles | 2022
    Chen RF; Braidy N; Xu YH; Tan S; Chan DKY, 2022, 'Macrophage-and Microglia-Related Chemokines Are Associated with Small Vessel (White Matter) Vascular Dementia: A Case-Control Study', Dementia and Geriatric Cognitive Disorders, 50, pp. 454 - 459, http://dx.doi.org/10.1159/000519885
    Journal articles | 2022
    Dai J; Saleheen S; Ko A; Jahan I; Braidy N; Chan DKY, 2022, 'Video-based fall prevention education for cognitively impaired inpatients: a pilot study', Asian Journal of Gerontology and Geriatrics, 17, pp. 11 - 16, http://dx.doi.org/10.12809/ajgg-2021-490-oa
    Journal articles | 2022
    Dehhaghi M; Panahi HKS; Kavyani B; Heng B; Tan V; Braidy N; Guillemin GJ, 2022, 'The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome', Aging and Disease, 13, pp. 698 - 711, http://dx.doi.org/10.14336/AD.2021.0824
    Journal articles | 2022
    Kim CK; Sachdev PS; Braidy N, 2022, 'Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?', Aging and Disease, 13, pp. 175 - 214, http://dx.doi.org/10.14336/AD.2021.0705
    Journal articles | 2022
    Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2022, 'Antioxidant, antimicrobial and neuroprotective effects of Octaviania asterosperma in vitro (vol 12, pg 128)', MYCOLOGY-AN INTERNATIONAL JOURNAL ON FUNGAL BIOLOGY, http://dx.doi.org/10.1080/21501203.2022.2073697
    Journal articles | 2021
    Ahmed T; Braidy N, 2021, 'Editorial: From Oxidative Stress to Cognitive Decline - Towards Novel Therapeutic Approaches', Frontiers in Molecular Neuroscience, 14, http://dx.doi.org/10.3389/fnmol.2021.650498
    Journal articles | 2021
    Atanasov AG; Zotchev SB; Dirsch VM; Orhan IE; Banach M; Rollinger JM; Barreca D; Weckwerth W; Bauer R; Bayer EA; Majeed M; Bishayee A; Bochkov V; Bonn GK; Braidy N; Bucar F; Cifuentes A; D’Onofrio G; Bodkin M; Diederich M; Dinkova-Kostova AT; Efferth T; El Bairi K; Arkells N; Fan TP; Fiebich BL; Freissmuth M; Georgiev MI; Gibbons S; Godfrey KM; Gruber CW; Heer J; Huber LA; Ibanez E; Kijjoa A; Kiss AK; Lu A; Macias FA; Miller MJS; Mocan A; Müller R; Nicoletti F; Perry G; Pittalà V; Rastrelli L; Ristow M; Russo GL; Silva AS; Schuster D; Sheridan H; Skalicka-Woźniak K; Skaltsounis L; Sobarzo-Sánchez E; Bredt DS; Stuppner H; Sureda A; Tzvetkov NT; Vacca RA; Aggarwal BB; Battino M; Giampieri F; Wink M; Wolfender JL; Xiao J; Yeung AWK; Lizard G; Popp MA; Heinrich M; Berindan-Neagoe I; Stadler M; Daglia M; Verpoorte R; Supuran CT, 2021, 'Natural products in drug discovery: advances and opportunities', Nature Reviews Drug Discovery, 20, pp. 200 - 216, http://dx.doi.org/10.1038/s41573-020-00114-z
    Journal articles | 2021
    Braidy N; Alicajic H; Pow D; Smith J; Jugder BE; Brew BJ; Nicolazzo JA; Guillemin GJ, 2021, 'Potential Mechanism of Cellular Uptake of the Excitotoxin Quinolinic Acid in Primary Human Neurons', Molecular Neurobiology, 58, pp. 34 - 54, http://dx.doi.org/10.1007/s12035-020-02046-6
    Journal articles | 2021
    Braidy N; Smani T; Naziroglu M, 2021, 'Editorial: Involvements of TRP Channels, Oxidative Stress and Apoptosis in Neurodegenerative Diseases', Frontiers in Physiology, 12, http://dx.doi.org/10.3389/fphys.2021.649230
    Journal articles | 2021
    Braidy N; Villalva MD; Grant R, 2021, 'Nadomics: Measuring nad+ and related metabolites using liquid chromatography mass spectrometry', Life, 11, pp. 512 - 512, http://dx.doi.org/10.3390/life11060512
    Journal articles | 2021
    Braidy N; Wen W; Bongers A; Sachdev PS, 2021, 'Applications of magnetic particle imaging in the dementias', Current Opinion in Psychiatry, 34, pp. 186 - 192, http://dx.doi.org/10.1097/YCO.0000000000000668
    Journal articles | 2021
    Camaya I; Mok TY; Lund M; To J; Braidy N; Robinson MW; Santos J; O’Brien B; Donnelly S, 2021, 'The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells', Journal of Molecular Medicine, 99, pp. 1605 - 1621, http://dx.doi.org/10.1007/s00109-021-02122-x
    Journal articles | 2021
    Chiang S; Braidy N; Maleki S; Lal S; Richardson DR; Huang MLH, 2021, 'Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation', Redox Biology, 46, pp. 102038 - 102038, http://dx.doi.org/10.1016/j.redox.2021.102038
    Journal articles | 2021
    Joisten N; Ruas JL; Braidy N; Guillemin GJ; Zimmer P, 2021, 'The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?', Trends in Molecular Medicine, 27, pp. 946 - 954, http://dx.doi.org/10.1016/j.molmed.2021.07.006
    Journal articles | 2021
    Liu Y; Chen Z; Li B; Yao H; Zarka M; Welch J; Sachdev P; Bridge W; Braidy N, 2021, 'Supplementation with γ-glutamylcysteine (γ-GC) lessens oxidative stress, brain inflammation and amyloid pathology and improves spatial memory in a murine model of AD', Neurochemistry International, 144, pp. 104931, http://dx.doi.org/10.1016/j.neuint.2020.104931
    Journal articles | 2021
    Liu Y; Thalamuthu A; Mather KA; Crawford J; Ulanova M; Wong MWK; Pickford R; Sachdev PS; Braidy N, 2021, 'Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes', Translational Psychiatry, 11, http://dx.doi.org/10.1038/s41398-021-01362-2
    Journal articles | 2021
    Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2021, 'Antioxidant, antimicrobial and neuroprotective effects of Octaviania asterosperma in vitro', Mycology, 12, pp. 128 - 138, http://dx.doi.org/10.1080/21501203.2020.1816584
    Journal articles | 2021
    Tewari D; Sah AN; Bawari S; Nabavi SF; Dehpour AR; Shirooie S; Braidy N; Fiebich BL; Vacca RA; Nabavi SM, 2021, 'Role of nitric oxide in neurodegeneration: Function, regulation, and inhibition', Current Neuropharmacology, 19, pp. 114 - 126, http://dx.doi.org/10.2174/1570159X18666200429001549
    Journal articles | 2021
    Villalva MD; Agarwal V; Ulanova M; Sachdev PS; Braidy N, 2021, 'Quantum dots as a theranostic approach in Alzheimer's disease: A systematic review', Nanomedicine, 16, pp. 1595 - 1611, http://dx.doi.org/10.2217/nnm-2021-0104
    Journal articles | 2020
    Braidy N; Liu Y, 2020, 'Can nicotinamide riboside protect against cognitive impairment?', Current Opinion in Clinical Nutrition and Metabolic Care, 23, pp. 413 - 420, http://dx.doi.org/10.1097/MCO.0000000000000691
    Journal articles | 2020
    Braidy N; Liu Y, 2020, 'NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis', Experimental Gerontology, 132, http://dx.doi.org/10.1016/j.exger.2020.110831
    Journal articles | 2020
    Braidy N; Villalva MD; van Eeden S, 2020, 'Sobriety and satiety: Is NAD+ the answer?', Antioxidants, 9, http://dx.doi.org/10.3390/antiox9050425
    Journal articles | 2020
    Chan LKM; Braidy N; Ng W; Xu YH; Chen J; McDonald R; Chan DKY, 2020, 'Re-pigmentation of hair after prolonged cholinesterase inhibitor therapy in a Chinese population', Australasian Journal of Dermatology, 61, pp. e417 - e420, http://dx.doi.org/10.1111/ajd.13356
    Journal articles | 2020
    Chiang S; Kalinowski DS; Dharmasivam M; Braidy N; Richardson DR; Huang MLH, 2020, 'The potential of the novel NAD+ supplementing agent, SNH6, as a therapeutic strategy for the treatment of Friedreich's ataxia', Pharmacological Research, 155, http://dx.doi.org/10.1016/j.phrs.2020.104680
    Journal articles | 2020
    Dehhaghi M; Kazemi Shariat Panahi H; Braidy N; Guillemin GJ, 2020, 'Herpetosiphon Secondary Metabolites Inhibit Amyloid-β Toxicity in Human Primary Astrocytes', Journal of Alzheimer's Disease, 76, pp. 423 - 433, http://dx.doi.org/10.3233/JAD-200116
    Journal articles | 2020
    Gloag L; Mehdipour M; Ulanova M; Mariandry K; Nichol MA; Hernández-Castillo DJ; Gaudet J; Qiao R; Zhang J; Nelson M; Thierry B; Alvarez-Lemus MA; Tan TT; Gooding JJ; Braidy N; Sachdev PS; Tilley RD, 2020, 'Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers', Chemical Communications, http://dx.doi.org/10.1039/c9cc08972a
    Journal articles | 2020
    Hosseini M; Poljak A; Braidy N; Crawford J; Sachdev P, 2020, 'Blood fatty acids in Alzheimer's disease and mild cognitive impairment: A meta-analysis and systematic review', Ageing Research Reviews, 60, pp. 101043, http://dx.doi.org/10.1016/j.arr.2020.101043
    Journal articles | 2020
    Iqbal G; Braidy N; Ahmed T, 2020, 'Blood-Based Biomarkers for Predictive Diagnosis of Cognitive Impairment in a Pakistani Population', Frontiers in Aging Neuroscience, 12, http://dx.doi.org/10.3389/fnagi.2020.00223
    Journal articles | 2020
    Kamran SKS; Rasul A; Anwar H; Irfan S; Ullah KS; Malik SA; Razzaq A; Aziz N; Braidy N; Hussain G, 2020, 'Ferula asafoetida Linn. is effective for early functional recovery following mechanically induced insult to the sciatic nerve of a mouse model', Tropical Journal of Pharmaceutical Research, 19, pp. 1903 - 1910, http://dx.doi.org/10.4314/tjpr.v19i9.15
    Journal articles | 2020
    Kaur G; Poljak A; Braidy N; Crawford JD; Lo J; Sachdev PS, 2020, 'Fluid Biomarkers and APOE Status of Early Onset Alzheimer’s Disease Variants: A Systematic Review and Meta-Analysis', Journal of Alzheimer's Disease, pp. 1 - 17, http://dx.doi.org/10.3233/jad-200052
    Journal articles | 2020
    Liu Y; Chan DKY; Crawford JD; Sachdev PS; Braidy N, 2020, 'The contribution of cerebral vascular neuropathology to mild stage of alzheimer’s dementia using the nacc database', Current Alzheimer Research, 17, pp. 1167 - 1176, http://dx.doi.org/10.2174/1567205018666210212160902
    Journal articles | 2020
    Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, 18, pp. 1613 - 1624, http://dx.doi.org/10.1016/j.csbj.2020.06.001
    Journal articles | 2020
    Ozdemir B; Selamoglu Z; Braidy N, 2020, 'Absolute Quantification of Plasma Apolipoproteins for Cardiovascular Disease Risk Prediction', Methods in molecular biology (Clifton, N.J.), 2138, pp. 373 - 379, http://dx.doi.org/10.1007/978-1-0716-0471-7_27
    Journal articles | 2020
    Razzaq A; Hussain G; Rasul A; Xu J; Zhang Q; Malik SA; Anwar H; Aziz N; Braidy N; de Aguilar JLG; Wei W; Li J; Li X, 2020, 'Strychnos nux-vomica L. seed preparation promotes functional recovery and attenuates oxidative stress in a mouse model of sciatic nerve crush injury', BMC complementary medicine and therapies, 20, pp. 181, http://dx.doi.org/10.1186/s12906-020-02950-3
    Journal articles | 2020
    Sakharkar MK; Dhillon SK; Rajamanickam K; Heng B; Braidy N; Guillemin GJ; Yang J, 2020, 'Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis', International Journal of Tryptophan Research, 13, pp. 117864692097701 - 117864692097701, http://dx.doi.org/10.1177/1178646920977013
    Journal articles | 2020
    Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2020, 'Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey', Oxidative Medicine and Cellular Longevity, 2020, pp. 5620484, http://dx.doi.org/10.1155/2020/5620484
    Journal articles | 2020
    Ulanova M; Gloag L; Bongers A; Gooding J; Biazik J; Tilley R; Sachdev PS; Braidy N, 2020, 'Magnetic nanoparticles as MRI contrast agents for the diagnosis of Alzheimer’s disease', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.041609
    Journal articles | 2020
    Ulanova M; Poljak A; Wen W; Bongers A; Gloag L; Gooding J; Tilley R; Sachdev P; Braidy N, 2020, 'Nanoparticles as contrast agents for the diagnosis of Alzheimer’s disease: a systematic review', Nanomedicine, http://dx.doi.org/10.2217/nnm-2019-0316
    Journal articles | 2020
    Wong MWK; Thalamuthu A; Braidy N; Mather K; Liu Y; Ciobanu L; Baune B; Armstrong N; Kwok J; Schofield P; Wright M; Ames D; Pickford R; Lee T; Poljak A; Sachdev P, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins', , http://dx.doi.org/10.1101/2020.05.05.075606
    Journal articles | 2020
    Wong MWK; Thalamuthu A; Braidy N; Mather KA; Liu Y; Ciobanu L; Baune BT; Armstrong NJ; Kwok J; Schofield P; Wright MJ; Ames D; Pickford R; Lee T; Poljak A; Sachdev PS, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', eLife, 9, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.58954
    Journal articles | 2020
    Wu Z; Palanimuthu D; Braidy N; Salikin NH; Egan S; Huang MLH; Richardson DR, 2020, 'Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios', British Journal of Pharmacology, 177, pp. 1967 - 1987, http://dx.doi.org/10.1111/bph.14963
    Journal articles | 2019
    Braidy N; Berg J; Clement J; Khorshidi F; Poljak A; Jayasena T; Grant R; Sachdev PS, 2019, 'Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes', Antioxidants and Redox Signaling, 30, pp. 251 - 294, http://dx.doi.org/10.1089/ars.2017.7269
    Journal articles | 2019
    Braidy N; Zarka M; Jugder B-E; Welch J; Jayasena T; Chan DKY; Sachdev P; Bridge W, 2019, 'The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes', Frontiers in Aging Neuroscience, 11, pp. 1 - 1, http://dx.doi.org/10.3389/fnagi.2019.00177
    Journal articles | 2019
    Chen Z; Jiang R; Chen M; Zheng J; Chen M; Braidy N; Liu S; Liu G; Maimaitiming Z; Shen T; Dunaief JL; Vulpe CD; Anderson GJ; Chen H, 2019, 'Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-46019-9
    Journal articles | 2019
    Clement J; Wong M; Poljak A; Sachdev P; Braidy N, 2019, 'The Plasma NAD⁺ Metabolome Is Dysregulated in "normal" Aging', Rejuvenation Research, 22, pp. 121 - 130, http://dx.doi.org/10.1089/rej.2018.2077
    Journal articles | 2019
    Dehhaghi M; Tan V; Heng B; Braidy N; Mohammadipanah F; Guillemin GJ, 2019, 'Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons', Neurotoxicity Research, 35, pp. 281 - 290, http://dx.doi.org/10.1007/s12640-018-9945-8
    Journal articles | 2019
    Ertilav K; Nazıroğlu M; Ataizi ZS; Braidy N, 2019, 'Selenium Enhances the Apoptotic Efficacy of Docetaxel Through Activation of TRPM2 Channel in DBTRG Glioblastoma Cells', Neurotoxicity Research, 35, pp. 797 - 808, http://dx.doi.org/10.1007/s12640-019-0009-5
    Journal articles | 2019
    Farzaei MH; Bahramsoltani R; Abbasabadi Z; Braidy N; Nabavi SM, 2019, 'Role of green tea catechins in prevention of age-related cognitive decline: Pharmacological targets and clinical perspective', Journal of Cellular Physiology, 234, pp. 2447 - 2459, http://dx.doi.org/10.1002/jcp.27289
    Journal articles | 2019
    Nabavi SF; Sureda A; Sanches-Silva A; Pandima Devi K; Ahmed T; Shahid M; Sobarzo-Sánchez E; Dacrema M; Daglia M; Braidy N; Vacca RA; Berindan-Neagoe I; Gulei D; Barreca D; Banach M; Nabavi SM; Dehpour AR; Shirooie S, 2019, 'Novel therapeutic strategies for stroke: The role of autophagy', Critical Reviews in Clinical Laboratory Sciences, 56, pp. 182 - 199, http://dx.doi.org/10.1080/10408363.2019.1575333
    Journal articles | 2019
    Vacca RA; Bawari S; Valenti D; Tewari D; Nabavi SF; Shirooie S; Sah AN; Volpicella M; Braidy N; Nabavi SM, 2019, 'Down syndrome: Neurobiological alterations and therapeutic targets', Neuroscience and Biobehavioral Reviews, 98, pp. 234 - 255, http://dx.doi.org/10.1016/j.neubiorev.2019.01.001
    Journal articles | 2019
    Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524
    Journal articles | 2019
    Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879
    Journal articles | 2019
    Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', PLoS ONE, 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141
    Journal articles | 2019
    Öztürk Y; Günaydın C; Yalçın F; Nazıroğlu M; Braidy N, 2019, 'Resveratrol enhances apoptotic and oxidant effects of paclitaxel through TRPM2 channel activation in DBTRG glioblastoma cells', Oxidative Medicine and Cellular Longevity, 2019, pp. 4619865, http://dx.doi.org/10.1155/2019/4619865
    Journal articles | 2018
    Amiri M; Braidy N; Aminzadeh M, 2018, 'Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta1–42-Induced Toxicity in SH-SY5Y Cells', Neurotoxicity Research, 34, pp. 574 - 583, http://dx.doi.org/10.1007/s12640-018-9914-2
    Journal articles | 2018
    BRAIDY N, 2018, 'Intravenous NAD+ effectively increased the NAD metabolome, reduced oxidative stress and inflammation, and increased expression of longevity genes safely in elderly humans', Journal of Cellular Neuroscience and Oxidative Stress, 10, pp. 779 - 779, http://dx.doi.org/10.37212/jcnos.610084
    Journal articles | 2018
    Braidy N; Grant R; Sachdev PS, 2018, 'Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease', Current Opinion in Psychiatry, 31, pp. 160 - 166, http://dx.doi.org/10.1097/yco.0000000000000394
    Journal articles | 2018
    Bustamante S; Jayasena T; Richani D; Gilchrist RB; Wu LE; Sinclair DA; Sachdev PS; Braidy N, 2018, 'Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach', Metabolomics, 14, http://dx.doi.org/10.1007/s11306-017-1310-z
    Journal articles | 2018
    Liu Y; Braidy N; Poljak A; Chan DK; Sachdev PS, 2018, 'Cerebral small vessel disease and the risk of Alzheimer's disease: A systematic review', Ageing Research Reviews, 47, pp. 41 - 48, http://dx.doi.org/10.1016/j.arr.2018.06.002
    Journal articles | 2018
    Liu Y; Clement J; Grant R; Sachdev PS; Braidy N, 2018, 'Quantitation of NAD+: Why do we need to measure it?', BBA - Biochimica et Biophysica Acta, 1862, pp. 2527 - 2532, http://dx.doi.org/10.1016/j.bbagen.2018.07.023
    Journal articles | 2018
    Mello FD; Braidy N; Marçal H; Guillemin G; Nabavi SM; Neilan BA, 2018, 'Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review', Neurotoxicity Research, 33, pp. 153 - 167, http://dx.doi.org/10.1007/s12640-017-9780-3
    Journal articles | 2018
    Nabavi SF; Sureda A; Dehpour AR; Shirooie S; Silva AS; Devi KP; Ahmed T; Ishaq N; Hashim R; Sobarzo-Sánchez E; Daglia M; Braidy N; Volpicella M; Vacca RA; Nabavi SM, 2018, 'Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration', Biotechnology Advances, 36, pp. 1768 - 1778, http://dx.doi.org/10.1016/j.biotechadv.2017.12.001
    Journal articles | 2018
    Nabavi SM; Nabavi SF; Sureda A; Caprioli G; Iannarelli R; Sokeng AJT; Braidy N; Khanjani S; Moghaddam AH; Atanasov AG; Daglia M; Maggi F, 2018, 'The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression', Biomedicine and Pharmacotherapy, 99, pp. 290 - 298, http://dx.doi.org/10.1016/j.biopha.2018.01.073
    Journal articles | 2018
    Palanimuthu D; Wu Z; Jansson PJ; Braidy N; Bernhardt PV; Richardson DR; Kalinowski DS, 2018, 'Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease', Dalton Transactions, 47, pp. 7190 - 7205, http://dx.doi.org/10.1039/c8dt01099d
    Journal articles | 2018
    Seyedsadjadi N; Berg J; Bilgin AA; Braidy N; Salonikas C; Grant R, 2018, 'High protein intake is associated with low plasma NAD+ levels in a healthy human cohort', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0201968
    Journal articles | 2018
    Valenti D; Braidy N; De Rasmo D; Signorile A; Rossi L; Atanasov AG; Volpicella M; Henrion-Caude A; Nabavi SM; Vacca RA, 2018, 'Mitochondria as pharmacological targets in Down syndrome', Free Radical Biology and Medicine, 114, pp. 69 - 83, http://dx.doi.org/10.1016/j.freeradbiomed.2017.08.014
    Journal articles | 2018
    2018, 'Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain', Journal of Cellular Physiology, 233, pp. 2705 - 2714, http://dx.doi.org/10.1002/jcp.26044
    Journal articles | 2017
    Ahmed T; Javed S; Javed S; Tariq A; Šamec D; Tejada S; Nabavi SF; Braidy N; Nabavi SM, 2017, 'Resveratrol and Alzheimer’s Disease: Mechanistic Insights', Molecular Neurobiology, 54, pp. 2622 - 2635, http://dx.doi.org/10.1007/s12035-016-9839-9
    Journal articles | 2017
    Ajami M; Pazoki-Toroudi H; Amani H; Nabavi SF; Braidy N; Vacca RA; Atanasov AG; Mocan A; Nabavi SM, 2017, 'Therapeutic role of sirtuins in neurodegenerative disease and their modulation by polyphenols', Neuroscience and Biobehavioral Reviews, 73, pp. 39 - 47, http://dx.doi.org/10.1016/j.neubiorev.2016.11.022
    Journal articles | 2017
    Braidy N; Behzad S; Habtemariam S; Ahmed T; Daglia M; Nabavi SM; Sobarzo-Sanchez E; Nabavi SF, 2017, 'Neuroprotective effects of citrus fruit-derived flavonoids, nobiletin and tangeretin in Alzheimer’s and Parkinson’s disease', CNS and Neurological Disorders - Drug Targets, 16, pp. 387 - 397, http://dx.doi.org/10.2174/1871527316666170328113309
    Journal articles | 2017
    Braidy N; Grant R, 2017, 'Kynurenine pathway metabolism and neuroinflammatory disease', Neural Regeneration Research, 12, pp. 39 - 42, http://dx.doi.org/10.4103/1673-5374.198971
    Journal articles | 2017
    Braidy N; Jugder B-E; Poljak A; Jayasena T; Nabavi SM; Sachdev P; Grant R, 2017, 'Molecular targets of Tannic Acid in Alzheimer’s disease', Curr Alzheimer Res, 14, pp. 861 - 869, http://dx.doi.org/10.2174/1567205014666170206163158
    Journal articles | 2017
    Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder B-E; Jayasena T; Inestrosa N; Sachdev P, 2017, 'Identification of cerebral metal ion imbalance in the brain of ageing Octodon degus', Frontiers in Aging Neuroscience, 9, pp. 66 - 66, http://dx.doi.org/10.3389/fnagi.2017.00066
    Journal articles | 2017
    Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder BE; Jayasena T; Inestrosa NC; Sachdev PS, 2017, 'Corrigendum: Identification of cerebral metal ion imbalance in the brain of ageing octodon degus [Front. Aging Neurosci., 9, (2017) (66)] DOI: 10.3389/fnagi.2017.00066', Frontiers in Aging Neuroscience, 9, http://dx.doi.org/10.3389/fnagi.2017.00134
    Journal articles | 2017
    Braidy N, 2017, 'Meet our editorial board member', Current Alzheimer Research, 14, pp. 123, http://dx.doi.org/10.2174/156720501402170109162607
    Journal articles | 2017
    Chan DKY; Xu YH; Chan LKM; Braidy N; Mellick GD, 2017, 'Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson's disease', Translational Neurodegeneration, 6, http://dx.doi.org/10.1186/s40035-017-0104-6
    Journal articles | 2017
    Daglia M; Lorenzo AD; Nabavi SF; Sureda A; Khanjani S; Moghaddam AH; Braidy N; Nabavi SM, 2017, 'Improvement of antioxidant defences and mood status by oral GABA tea administration in a mouse model of post-stroke depression', Nutrients, 9, http://dx.doi.org/10.3390/nu9050446
    Journal articles | 2017
    Devi KP; Malar DS; Braidy N; Nabavi SM; Nabavi SF, 2017, 'A Mini Review on the Chemistry and Neuroprotective Effects of Silymarin', Current drug targets, 18, pp. 1529 - 1536, http://dx.doi.org/10.2174/1389450117666161227125121
    Journal articles | 2017
    D‘Mello F; Braidy N; Marçal H; Guillemin G; Rossi F; Chinian M; Laurent D; Teo C; Neilan BA, 2017, 'Cytotoxic Effects of Environmental Toxins on Human Glial Cells', Neurotoxicity Research, 31, pp. 245 - 258, http://dx.doi.org/10.1007/s12640-016-9678-5
    Journal articles | 2017
    Gokoolparsadh A; Fang Z; Braidy N; Lin P; Pardy CJ; Eapen V; Clarke R; Voineagu I, 2017, 'Transcriptional response to mitochondrial protease IMMP2L knockdown in human primary astrocytes', Biochemical and Biophysical Research Communications, 482, pp. 1252 - 1258, http://dx.doi.org/10.1016/j.bbrc.2016.12.024
    Journal articles | 2017
    Gokoolparsadh A; Fang Z; Braidy N; Voineagu I, 2017, 'Topoisomerase I inhibition leads to length-dependent gene expression changes in human primary astrocytes', Genomics Data, 11, pp. 113 - 115, http://dx.doi.org/10.1016/j.gdata.2016.12.005
    Journal articles | 2017
    Lee JM; Tan V; Lovejoy D; Braidy N; Rowe DB; Brew BJ; Guillemin GJ, 2017, 'Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis', Neuropharmacology, 112, pp. 346 - 364, http://dx.doi.org/10.1016/j.neuropharm.2016.05.011
    Journal articles | 2017
    Lim CK; Fernández-Gomez FJ; Braidy N; Estrada C; Costa C; Costa S; Bessede A; Fernandez-Villalba E; Zinger A; Herrero MT; Guillemin GJ, 2017, 'Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease', Progress in Neurobiology, 155, pp. 76 - 95, http://dx.doi.org/10.1016/j.pneurobio.2015.12.009
    Journal articles | 2017
    Mirzaei M; Gupta VB; Chick JM; Greco TM; Wu Y; Chitranshi N; Wall RV; Hone E; Deng L; Dheer Y; Abbasi M; Rezaeian M; Braidy N; You Y; Salekdeh GH; Haynes PA; Molloy MP; Martins R; Cristea IM; Gygi SP; Graham SL; Gupta VK, 2017, 'Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-12858-7
    Journal articles | 2017
    Naziroğlu M; Braidy N, 2017, 'Thermo-sensitive TRP channels: Novel targets for treating chemotherapy-induced peripheral pain', Frontiers in Physiology, 8, http://dx.doi.org/10.3389/fphys.2017.01040
    Journal articles | 2017
    Rahimifard M; Maqbool F; Moeini-Nodeh S; Niaz K; Abdollahi M; Braidy N; Nabavi SM; Nabavi SF, 2017, 'Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation', Ageing Research Reviews, 36, pp. 11 - 19, http://dx.doi.org/10.1016/j.arr.2017.02.004
    Journal articles | 2017
    Shariflou S; Georgevsky D; Mansour H; Rezaeian M; Hosseini N; Gani F; Gupta V; Braidy N; Golzan SM, 2017, 'Diagnostic and prognostic potential of retinal biomarkers in early on-set Alzheimer’s disease', Current Alzheimer Research, 14, pp. 1000 - 1007, http://dx.doi.org/10.2174/1567205014666170329114445
    Journal articles | 2017
    Srinivasan V; Braidy N; Xu YH; Xie P; Kancherla K; Chandramohan S; Chan EKW; Chan DKY, 2017, 'Association of genetic polymorphisms of claudin-1 with small vessel vascular dementia', Clinical and Experimental Pharmacology and Physiology, 44, pp. 623 - 630, http://dx.doi.org/10.1111/1440-1681.12747
    Journal articles | 2017
    Talarek S; Listos J; Barreca D; Tellone E; Sureda A; Nabavi SF; Braidy N; Nabavi SM, 2017, 'Neuroprotective effects of honokiol: from chemistry to medicine', BioFactors, 43, pp. 760 - 769, http://dx.doi.org/10.1002/biof.1385
    Journal articles | 2017
    Tejada S; Setzer WN; Daglia M; Nabavi SF; Sureda A; Braidy N; Gortzi O; Nabavi SM, 2017, 'Neuroprotective Effects of Ellagitannins: A Brief Review', Current drug targets, 18, pp. 1518 - 1528, http://dx.doi.org/10.2174/1389450117666161005112002
    Journal articles | 2017
    Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, 13, pp. 810 - 827, http://dx.doi.org/10.1016/j.jalz.2017.01.008
    Journal articles | 2017
    Wong MW; Braidy N; Poljak A; Sachdev PS, 2017, 'The application of lipidomics to biomarker research and pathomechanisms in Alzheimer's disease', Current Opinion in Psychiatry, 30, pp. 136 - 144, http://dx.doi.org/10.1097/YCO.0000000000000303
    Journal articles | 2016
    Ahmed T; Raza SH; Maryam A; Setzer WN; Braidy N; Nabavi SF; De Oliveira MR; Nabavi SM, 2016, 'Ginsenoside Rb1 as a neuroprotective agent: A review', Brain Research Bulletin, 125, pp. 30 - 43, http://dx.doi.org/10.1016/j.brainresbull.2016.04.002
    Journal articles | 2016
    Ahmed T; Setzer WN; Nabavi SF; Orhan IE; Braidy N; Sobarzo-Sanchez E; Nabavi SM, 2016, 'Insights into effects of ellagic acid on the nervous system: A mini review', Current Pharmaceutical Design, 22, pp. 1350 - 1360, http://dx.doi.org/10.2174/1381612822666160125114503
    Journal articles | 2016
    Braidy N; Essa MM; Poljak A; Selvaraju S; Al-Adawi S; Manivasagm T; Thenmozhi AJ; Ooi L; Sachdev P; Guillemin GJ, 2016, 'Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease', Oncotarget, 7, pp. 64589 - 64604, http://dx.doi.org/10.18632/oncotarget.10905
    Journal articles | 2016
    Braidy N; Jugder BE; Poljak A; Jayasena T; Mansour H; Nabavi SM; Sachdev P; Grant R, 2016, 'Resveratrol as a potential therapeutic candidate for the treatment and management of alzheimer’s disease', Current Topics in Medicinal Chemistry, 16, pp. 1951 - 1960, http://dx.doi.org/10.2174/1568026616666160204121431
    Journal articles | 2016
    Braidy N; Rossez H; Lim CK; Jugder BE; Brew BJ; Guillemin GJ, 2016, 'Characterization of the Kynurenine Pathway in CD8+ Human Primary Monocyte-Derived Dendritic Cells', Neurotoxicity Research, 30, pp. 620 - 632, http://dx.doi.org/10.1007/s12640-016-9657-x
    Journal articles | 2016
    Cao P; Braidy N; Zarka M; Welch J; Bridge W, 2016, 'Therapeutic Approaches to Modulating Glutathione Levels as a Pharmacological Strategy in Alzheimer's Disease (vol 12, pg 298, 2015)', CURRENT ALZHEIMER RESEARCH, 13, pp. 1198 - 1198, http://dx.doi.org/10.2174/156720501310160825221218
    Journal articles | 2016
    Chan DKY; Braidy N; Xu YH; Chataway T; Guo F; Guillemin GJ; Teo C; Gai WP, 2016, 'Interference of α-Synuclein Uptake by Monomeric β-Amyloid1–40 and Potential Core Acting Site of the Interference', Neurotoxicity Research, 30, pp. 479 - 485, http://dx.doi.org/10.1007/s12640-016-9644-2
    Journal articles | 2016
    Grant R; Berg J; Braidy N, 2016, 'Promoting NAD+ metabolism: A new target for treating degenerative disease', Journal of the Australasian College of Nutritional and Environmental Medicine, 35, pp. 3 - 10
    Journal articles | 2016
    Jayasena T; Poljak A; Braidy N; Zhong L; Rowlands B; Muenchhoff J; Grant R; Smythe G; Teo C; Raftery M; Sachdev PS, 2016, 'Application of targeted mass spectrometry for the quantification of sirtuins in the central nervous system', Scientific Reports, 6, pp. 35391 - 35391, http://dx.doi.org/10.1038/srep35391
    Journal articles | 2016
    Jugder ; Welch J; Braidy N; Marquis CP, 2016, 'Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter', PeerJ, 4, pp. e2269 - e2269, http://dx.doi.org/10.7717/peerj.2269
    Journal articles | 2016
    Jugder BE; Ertan H; Wong YK; Braidy N; Manefield M; Marquis CP; Lee M, 2016, 'Genomic, transcriptomic and proteomic analyses of dehalobacter UNSWDHB in response to chloroform', Environmental Microbiology Reports, 8, pp. 814 - 824, http://dx.doi.org/10.1111/1758-2229.12444
    Journal articles | 2016
    Nabavi SF; Braidy N; Habtemariam S; Sureda A; Manayi A; Nabavi SM, 2016, 'Neuroprotective effects of fisetin in alzheimer’s and parkinson’s diseases: From chemistry to medicine', Current Topics in Medicinal Chemistry, 16, pp. 1910 - 1915, http://dx.doi.org/10.2174/1568026616666160204121725
    Journal articles | 2016
    Nabavi SF; Braidy N; Orhan IE; Badiee A; Daglia M; Nabavi SM, 2016, 'Rhodiola rosea L. and Alzheimer's Disease: From Farm to Pharmacy', Phytotherapy Research, 30, pp. 532 - 539, http://dx.doi.org/10.1002/ptr.5569
    Journal articles | 2016
    Nabavi SF; Tejada S; Setzer WN; Gortzi O; Sureda A; Braidy N; Daglia M; Manayi A; Nabavi SM, 2016, 'Chlorogenic acid and mental diseases: From chemistry to medicine', Current Neuropharmacology, 14, http://dx.doi.org/10.2174/1570159X14666160325120625
    Journal articles | 2016
    Pazoki-Toroudi H; Amani H; Ajami M; Nabavi SF; Braidy N; Kasi PD; Nabavi SM, 2016, 'Targeting mTOR signaling by polyphenols: A new therapeutic target for ageing', Ageing Research Reviews, 31, pp. 55 - 66, http://dx.doi.org/10.1016/j.arr.2016.07.004
    Journal articles | 2016
    Srinivasan V; Braidy N; Chan EKW; Xu YH; Chan DKY, 2016, 'Genetic and environmental factors in vascular dementia: An update of blood brain barrier dysfunction', Clinical and Experimental Pharmacology and Physiology, 43, pp. 515 - 521, http://dx.doi.org/10.1111/1440-1681.12558
    Journal articles | 2016
    Subash S; Essa MM; Braidy N; Al-Jabri A; Vaishnav R; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2016, 'Consumption of fig fruits grown in Oman can improve memory, anxiety, and learning skills in a transgenic mice model of Alzheimer's disease', Nutritional Neuroscience, 19, pp. 475 - 483, http://dx.doi.org/10.1179/1476830514Y.0000000131
    Journal articles | 2016
    Suganthy N; Devi KP; Nabavi SF; Braidy N; Nabavi SM, 2016, 'Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions', Biomedicine and Pharmacotherapy, 84, pp. 892 - 908, http://dx.doi.org/10.1016/j.biopha.2016.10.011
    Journal articles | 2016
    Vacca RA; Valenti D; Caccamese S; Daglia M; Braidy N; Nabavi SM, 2016, 'Plant polyphenols as natural drugs for the management of Down syndrome and related disorders', Neuroscience and Biobehavioral Reviews, 71, pp. 865 - 877, http://dx.doi.org/10.1016/j.neubiorev.2016.10.023
    Journal articles | 2016
    de Oliveira MR; Nabavi SM; Braidy N; Setzer WN; Ahmed T; Nabavi SF, 2016, 'Quercetin and the mitochondria: A mechanistic view', Biotechnology Advances, 34, pp. 532 - 549, http://dx.doi.org/10.1016/j.biotechadv.2015.12.014
    Journal articles | 2015
    Al-Adawi S; Braidy N; Essa M; Al-Azri F; Hussain S; Al-Sibani N; Al-Khabouri J; Al-Asmi A; Al-Mashani A, 2015, 'Cognitive profiles in patients with multi-infarct dementia: an Omani study (vol 4, pg 271, 2014)', DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA, 5, pp. 285 - 285, http://dx.doi.org/10.1159/000430968
    Journal articles | 2015
    Bastías-Candia S; Braidy N; Zolezzi JM; Inestrosa NC, 2015, 'Teneurins and Alzheimer's disease: A suggestive role for a unique family of proteins', Medical Hypotheses, 84, pp. 402 - 407, http://dx.doi.org/10.1016/j.mehy.2015.01.026
    Journal articles | 2015
    Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Smythe G; Sachdev P; Guillemin GJ, 2015, 'Differential expression of sirtuins in the aging rat brain', Frontiers in Cellular Neuroscience, 9, http://dx.doi.org/10.3389/fncel.2015.00167
    Journal articles | 2015
    Braidy N; Poljak A; Jayasena T; Mansour H; Inestrosa NC; Sachdev PS, 2015, 'Accelerating Alzheimer's research through 'natural' animal models', Current Opinion in Psychiatry, 28, pp. 155 - 164, http://dx.doi.org/10.1097/YCO.0000000000000137
    Journal articles | 2015
    Braidy N; Zarka M; Welch J; Bridge W, 2015, 'Therapeutic approaches to modulating glutathione levels as a pharmacological strategy in Alzheimer’s disease', Current Alzheimer Research, 12, pp. 298 - 313, http://dx.doi.org/10.2174/1567205012666150302160308
    Journal articles | 2015
    Braidy N; nabavi SM; Daglia MD; Nabavi SF, 2015, 'Natural products, micronutrients, and nutraceuticals for the treatment of depression', Nutritional Neuroscience, 20, pp. 180 - 194, http://dx.doi.org/10.1080/1028415X.2015.1103461
    Journal articles | 2015
    Chiu AS; Braidy N; Marçal H; Welch JH; Gehringer MM; Guillemin GJ; Neilan BA, 2015, 'Global cellular responses to β-methyl-amino-l-alanine (BMAA) by olfactory ensheathing glial cells (OEC)', Toxicon, 99, pp. 136 - 145, http://dx.doi.org/10.1016/j.toxicon.2015.03.009
    Journal articles | 2015
    Inestrosa NC; Ríos JA; Cisternas P; Tapia-Rojas C; Rivera DS; Braidy N; Zolezzi JM; Godoy JA; Carvajal FJ; Ardiles AO; Bozinovic F; Palacios AG; Sachdev PS, 2015, 'Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease', Brain Pathology, 25, pp. 679 - 691, http://dx.doi.org/10.1111/bpa.12226
    Journal articles | 2015
    Jayasena T; Poljak A; Braidy N; Smythe G; Raftery M; Hill M; Brodaty H; Trollor J; Kochan N; Sachdev P, 2015, 'Upregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma', PLoS ONE, 10, pp. e0116092, http://dx.doi.org/10.1371/journal.pone.0116092
    Journal articles | 2015
    Nabavi SF; Braidy N; Gortzi O; Sobarzo-Sanchez E; Daglia M; Skalicka-Woźniak K; Nabavi SM, 2015, 'Luteolin as an anti-inflammatory and neuroprotective agent: A brief review', Brain Research Bulletin, 119, pp. 1 - 11, http://dx.doi.org/10.1016/j.brainresbull.2015.09.002
    Journal articles | 2015
    Nabavi SF; Braidy N; Habtemariam S; Orhan IE; Daglia M; Manayi A; Gortzi O; Nabavi SM, 2015, 'Neuroprotective effects of chrysin: From chemistry to medicine', Neurochemistry International, 90, pp. 224 - 231, http://dx.doi.org/10.1016/j.neuint.2015.09.006
    Journal articles | 2015
    Nabavi SM; Habtemariam S; Daglia M; Braidy N; Loizzo MR; Tundis R; Nabavi SF, 2015, 'Neuroprotective effects of ginkgolide B against ischemic stroke: A review of current literature', Current Topics in Medicinal Chemistry, 15, pp. 2222 - 2232, http://dx.doi.org/10.2174/1568026615666150610142647
    Journal articles | 2015
    Sheipouri D; Grant R; Bustamante S; Lovejoy D; Guillemin GJ; Braidy N, 2015, 'Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes', Journal of Cellular Biochemistry, 116, pp. 903 - 922, http://dx.doi.org/10.1002/jcb.25019
    Journal articles | 2015
    Subash S; Braidy N; Essa MM; Zayana AB; Ragini V; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2015, 'Long-term (15mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease', Nutrition, 31, pp. 223 - 229, http://dx.doi.org/10.1016/j.nut.2014.06.004
    Journal articles | 2015
    Subash S; Essa MM; Braidy N; Awlad-Thani K; Vaishnav R; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2015, 'Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease', Journal of Ayurveda and Integrative Medicine, 6, pp. 111 - 120, http://dx.doi.org/10.4103/0975-9476.159073
    Journal articles | 2014
    Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology', PLOS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0112945
    Journal articles | 2014
    Al-Adawi S; Braidy N; Essa M; Al-Azri F; Hussain S; Al-Sibani N; Al-Khabouri J; Al-Asmi A; Al-Mashani A, 2014, 'Cognitive Profiles in Patients with Multi-Infarct Dementia: An Omani Study', DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA, 4, pp. 271 - +, http://dx.doi.org/10.1159/000363621
    Journal articles | 2014
    Braidy N; Brew BJ; Inestrosa NC; Chung R; Sachdev P; Guillemin GJ, 2014, 'Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons', Metabolic Brain Disease, 29, pp. 873 - 883, http://dx.doi.org/10.1007/s11011-014-9557-9
    Journal articles | 2014
    Braidy N; Essa MM; Bridge WB; Subash SS; Manivasagam TM; Vijayan RKV; Al-Adawi SA; Guillemin GG, 2014, 'REVIEW OF NATURAL PRODUCTS ON PARKINSON’S DISEASE PATHOLOGY', Journal of Aging Research & Clinical Practice, 3, pp. 127 - 136
    Journal articles | 2014
    Braidy N; Gai W-P; Xu YH; Sachdev P; Guillemin GJ; Jiang X-M; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2014, 'Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro', Neurotoxicity Research, 25, pp. 170 - 182, http://dx.doi.org/10.1007/s12640-013-9420-5
    Journal articles | 2014
    Braidy N; Matin A; Rossi F; Chinain M; Laurent D; Guillemin GJ, 2014, 'Neuroprotective effects of rosmarinic acid on ciguatoxin in primary human neurons', Neurotoxicity Research, 25, pp. 226 - 234, http://dx.doi.org/10.1007/s12640-013-9429-9
    Journal articles | 2014
    Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev P, 2014, 'Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence', Biogerontology, 15, pp. 177 - 198, http://dx.doi.org/10.1007/s10522-013-9489-5
    Journal articles | 2014
    Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jayasena T; Inestrosa NC; Sachdev P, 2014, 'Metal and complementary molecular bioimaging in alzheimer's disease', Frontiers in Aging Neuroscience, 6, http://dx.doi.org/10.3389/fnagi.2014.00138
    Journal articles | 2014
    Braidy N; Subash SS; Essa MM; Al-Buraiki ZA; Vaishnav RV; Al-Adawi SA; Al-Asmi SA; Al-Senawi SA; Alobaidy HA; Lakhtakia RL; Guillemin GJ, 2014, 'NEUROPROTECTIVE EFFECTS OF A VARIETY OF POMEGRANATE JUICE EXTRACTS (PJE) AGAINST THE EXCITOTOXIN QUINOLINIC ACID IN HUMAN PRIMARY NEURONS', The Journal of Prevention of Alzheimer's disease, 1, pp. 84 - 90, http://dx.doi.org/10.14283/jpad.2014.3
    Journal articles | 2014
    Chen C; Upton C; Braidy N; Khalil J; Fang Z-M; Xu YH; Chan DKY, 2014, 'Association of leukocyte telomere length with vascular dementia and cancer mortality in an elderly population.', Journal of the American Geriatrics Society, 62, pp. 1384 - 1386, http://dx.doi.org/10.1111/jgs.12910
    Journal articles | 2014
    Essa MM; Braidy N; Bridge W; Subash S; Manivasagam T; Vijayan RK; Al-Adawi S; Guillemin GJ, 2014, 'REVIEW OF NATURAL PRODUCTS ON PARKINSON’S DISEASE PATHOLOGY', Journal of Aging Research and Lifestyle, pp. 1 - 10, http://dx.doi.org/10.14283/jarcp.2014.23
    Journal articles | 2014
    Godoy JA; Arrázola MS; Ordenes D; Silva-Alvarez C; Braidy N; Inestrosa NC, 2014, 'Wnt-5a ligand modulates mitochondrial fission-fusion in rat hippocampal neurons', Journal of Biological Chemistry, 289, pp. 36179 - 36193, http://dx.doi.org/10.1074/jbc.M114.557009
    Journal articles | 2014
    Godoy JA; Rios JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Signaling pathway cross talk in Alzheimer's disease', Cell Communication and Signaling, 12, http://dx.doi.org/10.1186/1478-811X-12-23
    Journal articles | 2014
    Godoy JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain', Molecular Neurobiology, 50, pp. 744 - 756, http://dx.doi.org/10.1007/s12035-014-8645-5
    Journal articles | 2014
    Godoy JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Role of Sirt1 during the ageing process: relevance to protection of synapses in the brain', Molecular neurobiology, 50, pp. 744 - 756, http://dx.doi.org/10.1007/s12035-014-8645-5
    Journal articles | 2014
    Subash S; Essa M; Al-Asmi A; Al-Adawi S; Vaishnav R; Braidy N; Manivasagam T; Guillemin G, 2014, 'Pomegranate from oman alleviates the brain oxidative damage in transgenic mouse model of alzheimer′s disease', Journal of Traditional and Complementary Medicine, 4, pp. 232 - 238, http://dx.doi.org/10.4103/2225-4110.139107
    Journal articles | 2013
    Al Asmi A; Al Maniri A; Al-Farsi YM; Burke DT; Al Asfoor FMH; Al Busaidi I; Al Breiki MHA; Lahiri S; Braidy N; Essa MM; Al-Adawi S, 2013, 'Types and sociodemographic correlates of complementary and alternative medicine (CAM) use among people with epilepsy in Oman', Epilepsy and Behavior, 29, pp. 361 - 366, http://dx.doi.org/10.1016/j.yebeh.2013.07.022
    Journal articles | 2013
    Braidy N; Gai WP; Xu YH; Sachdev P; Guillemin GJ; Jiang XM; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2013, 'Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts', Translational Neurodegeneration, 2, http://dx.doi.org/10.1186/2047-9158-2-20
    Journal articles | 2013
    Braidy N; Lim CK; Grant R; Brew BJ; Guillemin GJ, 2013, 'Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis', Brain Research, 1537, pp. 267 - 272, http://dx.doi.org/10.1016/j.brainres.2013.08.025
    Journal articles | 2013
    Braidy N; Selvaraju S; Essa MM; Vaishnav R; Al-Adawi S; Al-Asmi A; Al-Senawi H; Abd Alrahman Alobaidy A; Lakhtakia R; Guillemin GJ, 2013, 'Neuroprotective effects of a variety of pomegranate juice extracts against MPTP-induced cytotoxicity and oxidative stress in human primary neurons', Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2013/685909
    Journal articles | 2013
    Chiu AS; Gehringer MM; Braidy N; Guillemin GJ; Welch JH; Neilan BA, 2013, 'Gliotoxicity of the cyanotoxin, â-methyl-amino-L-alanine (BMAA)', Scientific Reports, 3, pp. 1 - 5, http://dx.doi.org/10.1038/srep01482
    Journal articles | 2013
    Essa M; Braidy N; Vijayan K; Subash ; Guillemin GJ, 2013, 'Excitotoxicity in the Pathogenesis of Autism', Neurotoxicity Research, 23, pp. 393 - 400, http://dx.doi.org/10.1007/s12640-012-9354-3
    Journal articles | 2013
    Essa M; Braidy N; Waly MI; Al-Farsi Y; Sharbati M; Subash ; Amanat A; Al-shaffae A; Guillemin GJ, 2013, 'Impaired Antioxidant Status and Reduced Energy Metabolism in Autistic Children', Research In Autism Spectrum Disorders, 7, pp. 557 - 565, http://dx.doi.org/10.1016/j.rasd.2012.12.006
    Journal articles | 2013
    Essa M; Selvaraju S; Braidy N; Al‐Asmi A; Al‐Adawi S; Al‐Senawi H; Vaishnav R; Guillemin GJ, 2013, 'P4–262: Neuro‐protective effects of pomegranate juice extracts on 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridin (MPTP)–induced neurotoxicity in human neurons', Alzheimer's & Dementia, 9, pp. P801 - P801, http://dx.doi.org/10.1016/j.jalz.2013.05.1655
    Journal articles | 2013
    Essa M; Subash ; Al-adawi ; Braidy N; Lim CK; Manivasagam T; Guillemin GJ, 2013, 'Role of NAD+, Oxidative Stress and Tryptophan Metabolism in Autism Spectrum Disorders', International Journal of Tryptophan Research : IJTR, 6, pp. 1 - 14, http://dx.doi.org/10.4137/IJTR.S11355
    Journal articles | 2013
    Essa M; Subash S; Braidy N; Al‐Adawi S; Al‐Asmi A; Al‐Senawi H; Vaishnav R; Guillemin GJ, 2013, 'P4–260: Neuroprotective effects of pomegranate juice extracts on quinolinic acid–induced excitotoxicity in human neurons', Alzheimer's & Dementia, 9, pp. P800 - P801, http://dx.doi.org/10.1016/j.jalz.2013.05.1653
    Journal articles | 2013
    Jayasena T; Braidy N; Sachdev P; Poljak A; Smythe G; Münch G, 2013, 'The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease', Ageing Research Reviews, 12, pp. 867 - 883, http://dx.doi.org/10.1016/j.arr.2013.06.003
    Journal articles | 2013
    Sachdev PS; Zhuang L; Braidy N; Wen W, 2013, 'Is Alzheimer’s a disease of the white matter?', Current Opinion in Psychiatry, 26, pp. 244 - 251, http://dx.doi.org/10.1097/YCO.0b013e32835ed6e8
    Journal articles | 2013
    Selvaraju S; Essa M; Braidy N; Al‐Adawi S; Al‐Asmi A; Al‐Senawi H; Vaishnav R; Guillemin GJ, 2013, 'P4–261: Anti‐oxidant and anti‐excitotoxic effects of date, fig and walnut extracts in human neurons', Alzheimer's & Dementia, 9, pp. P801 - P801, http://dx.doi.org/10.1016/j.jalz.2013.05.1654
    Journal articles | 2013
    Tamilselvam K; Braidy N; Manivasagam T; Essa MM; Prasad NR; Karthikeyan S; Thenmozhi AJ; Selvaraju S; Guillemin GJ, 2013, 'Neuroprotective effects of hesperidin, a plant flavanone, on rotenone-induced oxidative stress and apoptosis in a cellular model for Parkinson's disease', Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2013/102741
    Journal articles | 2012
    Adams S; Braidy N; Bess A; Brew BJ; Grant RS; Teo C; Guillemin GJ, 2012, 'The kynurenine pathway in brain tumor pathogenesis', Cancer research, 72, pp. 5649 - 5657, http://dx.doi.org/10.1158/0008-5472.CAN-12-0549
    Journal articles | 2012
    Braidy N; Jayasena T; Poljak A; Sachdev PS, 2012, 'Sirtuins in cognitive ageing and Alzheimer's disease', Current Opinion in Psychiatry, 25, pp. 226 - 230, http://dx.doi.org/10.1097/YCO.0b013e32835112c1
    Journal articles | 2012
    Braidy N; Munoz PC; Palacios AG; Castellano-Gonzalez G; Inestrosa NC; Chung RS; Sachdev PS; Guillemin GJ, 2012, 'Recent rodent models for Alzheimer's disease: Clinical implications and basic research', Journal of Neural Transmission, 119, pp. 173 - 195, http://dx.doi.org/10.1007/s00702-011-0731-5
    Journal articles | 2012
    Chiu AS; Gehringer MM; Braidy N; Guillemin GJ; Welch JH; Neilan BA, 2012, 'Excitotoxic potential of the cyanotoxin â-methyl-amino-l-alanine (BMAA) in primary human neurons', Toxicon, 60, pp. 1159 - 1165, http://dx.doi.org/10.1016/j.toxicon.2012.07.169
    Journal articles | 2012
    Essa MM; Vijayan R; Castellano-Gonzalez G; Memon M; Braidy N; Guillemin GJ, 2012, 'Neuroprotective Effect of Natural Products Against Alzheimer's Disease', Neurochemical Research, 37, pp. 1829 - 1842, http://dx.doi.org/10.1007/s11064-012-0799-9
    Journal articles | 2012
    Massudi H; Grant RS; Braidy N; Guest J; Farnsworth BN; Guillemin GJ, 2012, 'Age-associated changes in oxidative stress and NAD + metabolism in human tissue', PLoS One, 7, pp. e42357, http://dx.doi.org/10.1371/journal.pone.0042357
    Journal articles | 2012
    Massudi H; Grant RS; Guillemin GJ; Braidy N, 2012, 'NAD + metabolism and oxidative stress: The golden nucleotide on a crown of thorns', Redox Report, 17, pp. 28 - 46, http://dx.doi.org/10.1179/1351000212Y.0000000001
    Journal articles | 2012
    Sheipouri D; Braidy N; Guillemin GJ, 2012, 'Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage', International Journal of Tryptophan Research : IJTR, 5, pp. 15 - 25, http://dx.doi.org/10.4137/IJTR.S9835
    Journal articles | 2011
    Adams S; Braidy N; Teo C; Guillemin G, 2011, 'INVOLVEMENT OF THE KYNURENINE PATHWAY IN HUMAN PRIMARY GLIOBLASTOMA PATHOGENESIS', NEURO-ONCOLOGY, 13, pp. 69 - 69, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297026600283&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2011
    Braidy N; Bui K; Bajorek B, 2011, 'Evaluating the impact of new anticoagulants in the hospital setting', Pharmacy Practice, 9, pp. 1 - 10, http://dx.doi.org/10.4321/S1886-36552011000100001
    Journal articles | 2011
    Braidy N; Guillemin GJ; Grant RS, 2011, 'Effects of Kynurenine Pathway Inhibition on NAD+ Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.', International Journal of Tryptophan Research : IJTR, 4, pp. 29 - 37, http://dx.doi.org/10.4137/IJTR.S7052
    Journal articles | 2011
    Braidy N; Guillemin GJ; Hussein M; Chan-Ling T; Poljak A; Grant RS, 2011, 'Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats.', PLoS One, 6, pp. e19194, http://dx.doi.org/10.1371/journal.pone.0019194
    Journal articles | 2011
    Braidy N; Guillemin GJ; Mansour H; Chan-Ling T; Grant RS, 2011, 'Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats', FEBS Journal, 278, pp. 4425 - 4434, http://dx.doi.org/10.1111/j.1742-4658.2011.08366.x
    Journal articles | 2010
    Braidy N; Grant R; Adams S; Guillemin GJ, 2010, 'Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons', FEBS Journal, 277, pp. 368 - 382, http://dx.doi.org/10.1111/j.1742-4658.2009.07487.x
    Journal articles | 2010
    Braidy N; Guillemin G; Mansour H; Chan-Ling T; Grant R, 2010, 'P2‐251: Age‐related changes in NAD+ metabolism in the brain of aged Wister rats: Relevance for Alzheimer's disease', Alzheimer's & Dementia, 6, pp. S388 - S388, http://dx.doi.org/10.1016/j.jalz.2010.05.1301
    Journal articles | 2010
    Guillemin GJ; Rahman A; Ting K; Cullen KM; Braidy N; Chung RS; Wu W; Brew BJ, 2010, 'INVOLVEMENT OF THE KYNURENINE PATHWAY IN ALZHEIMER'S DISEASE', JOURNAL OF NEUROCHEMISTRY, 115, pp. 39 - 39, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281812600096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Guillemin GJ; Rahman A; Ting KK; Cullen K; Braidy N; Chung R; Wu W; Brew BJ, 2010, 'P4‐002: Involvement of the Kynurenine Pathway in Alzheimer's Disease', Alzheimer's & Dementia, 6, pp. e21 - e21, http://dx.doi.org/10.1016/j.jalz.2010.08.063
    Journal articles | 2009
    Braidy N; Grant RS; Adams S; Brew BJ; Guillemin GJ, 2009, 'Mechanism for quinolinic acid cytotoxicity in human astrocytes & neurons', Neurotoxicity Research, 16, pp. 77 - 86, http://dx.doi.org/10.1007/s12640-009-9051-z
    Journal articles | 2009
    Braidy N; Grant RS; Brew BJ; Adams S; Jayasena T; Guillemin GJ, 2009, 'Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons', International Journal of Tryptophan Research : IJTR, 2, pp. 61 - 69
    Journal articles | 2009
    Guillemin GJ; Rahman A; Cullen KM; Ting KK; Braidy N; Brew BJ, 2009, 'P3‐195: Involvement of the kynurenine pathway in Alzheimer's disease', Alzheimer's & Dementia, 5, pp. P400 - P400, http://dx.doi.org/10.1016/j.jalz.2009.04.1069
    Journal articles | 2009
    Rahman A; Ting K; Cullen KM; Braidy N; Brew BJ; Guillemin GJ, 2009, 'The excitotoxin quinolinic acid induces tau phosphorylation in human neurons', PLoS One, 4, pp. e6344 -1 - 15, http://dx.doi.org/10.1371/journal.pone.0006344
    Journal articles | 2008
    Braidy N; Guillemin GJ; Grant RS, 2008, 'Promotion of Cellular NAD Anabolism: Therapeutic Potential for Oxidative Stress in Aging & Alzheimer`s Disease', Neurotoxicity Research, 13, pp. 173 - 184, http://dx.doi.org/10.1007/BF03033501
  • Conference Abstracts | 2019
    Virk GK; Poljak A; Braidy N; Sachdev PS, 2019, 'Method development and proteomic analysis of depleted plasma for biomarker discovery in neurodegenerative diseases [Poster Abstract P2-219].S', in Alzheimer's & Dementia, Elsevier BV, Los Angeles, CA, USA, Vol. 15, pp. P661 - P661, presented at Alzheimer's Association International Conference (AAIC) 2019, Los Angeles, CA, USA, 14 July 2019 - 16 July 2019, http://dx.doi.org/10.1016/j.jalz.2019.06.2626
    Conference Abstracts | 2018
    Liu Y; Braidy N; Sachdev PS, 2018, 'Plasma lipidomics of vascular dementia [Abstact P3-259]', in Alzheimer's & Dementia, Elsevier BV, Chicago, USA, Vol. 14, pp. P1174 - P1174, presented at Alzheimer’s Association International Conference (AAIC) 2018, Chicago, USA, 22 July 2018 - 26 July 2018, http://dx.doi.org/10.1016/j.jalz.2018.06.1619
    Conference Abstracts | 2018
    Virk GK; Poljak A; Braidy N; Sachdev PS, 2018, 'CSF and blood biomarkers of early-onset Alzheimer’s disease: a systematic review and meta-analysis [Poster Abstract P3-226]', in Alzheimer's & Dementia, Elsevier BV, Chicago, USA, Vol. 14, pp. P1158 - P1158, presented at Alzheimer’s Association International Conference (AAIC) 2018, Chicago, USA, 22 July 2018 - 26 July 2018, http://dx.doi.org/10.1016/j.jalz.2018.06.1585
    Conference Abstracts | 2017
    Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Inestrosa N; Sachdev PS, 2017, 'Identification of Cerebral Metal Ion Imbalance in the Brain of Ageing Octodon Degu: a Natural Model for Alzheimer's Disease [Poster Abstract P2-080]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P636 - P637, presented at Alzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.729
    Conference Abstracts | 2017
    Jayasena T; Poljak A; Bustamante S; Braidy N; Raftery MJ; Sachdev PS, 2017, 'Sirtuin protein and related energy metabolite changes in the Alzheimer brain [Poster Abstract P2-182]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P676 - P676, presented at lzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.833
    Conference Abstracts | 2017
    Poljak A; Braidy N; Maclean C; Shepherd C; Raftery MJ; Sachdev PS, 2017, 'Proteomics of the Alzheimer's disease brain: Neuropathology and neuroresilience [Poster Abstract P2-155]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P667 - P667, presented at Alzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.806
    Preprints | 2016
    Jugder B-E; Welch J; Braidy N; Marquis CP, 2016, Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter (P SH ) fusion to gfp (green fluorescent protein), , http://dx.doi.org/10.7287/peerj.preprints.2120
    Preprints | 2016
    Jugder B-E; Welch J; Braidy N; Marquis CP, 2016, Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter (P SH ) fusion to gfp (green fluorescent protein), , http://dx.doi.org/10.7287/peerj.preprints.2120v1
    Conference Abstracts | 2016
    Jugder B; Ertan H; Braidy N; Lee M; Manefield M; Marquis CP, 2016, 'Transcriptomic and proteomic studies of Dehalobacter UNSWDHB reveal major changes during its organohalide respiration', in American Society of Microbiology Microbe, American Society of Microbiology Microbe, Boston, US, presented at American Society of Microbiology Microbe, Boston, US
    Conference Papers | 2014
    Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the kynurenine pathway in human glioma pathophysiology', in PLoS ONE, http://dx.doi.org/10.1371/journal.pone.0112945
    Conference Papers | 2014
    Subash S; Braidy N; Essa M; Al-Adawi S; Al-Asmi A; Vaishnav R; Guillemin G, 2014, 'Pomegranate ameliorates Alzheimer's disease-type neurodegeneration in tg 2576 mouse model', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, San Diego, presented at Experimental Biology Meeting, CA, San Diego, 26 April 2014 - 30 April 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346646705152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2013
    Braidy N; Poljak A; Zarka M; Bridge W; Sachdev P, 2013, 'γ-glutamylcysteine (GGC)-mediated upregulation of glutathione levels can ameliorate toxicity of natural beta-amyloid oligomers in primary adult human neurons [Abstract P4-332]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P854 - P854, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.08.166
    Conference Abstracts | 2013
    Jayasena T; Poljak A; Zhong L; Braidy N; Smythe G; Raftery M; Sachdev P, 2013, 'Development of a targeted mass spectrometry method for accurate quantification of human sirtuins in biological samples [Abstract P2-035]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P357 - P357, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.05.677
    Conference Abstracts | 2012
    Braidy N; Jayasena T; Poljak A; Smythe G; Guillemin G; Sachdev P, 2012, 'Sirtuin expression during aging and in Alzheimer's disease [Abstract P2-094]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, Vol. 8, pp. P295 - P296, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.798
    Conference Abstracts | 2012
    Braidy N; Poljak A; Jayasena T; Guillemin G; Smythe G; Sachdev P, 2012, 'NAD+ metabolism, and oxidative stress in the brain of aging Wistar rats: Is there a link? [Abstract P3-073]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, Vol. 8, pp. P478 - P478, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.1292
    Conference Posters | 2012
    Braidy N; Poljak A; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev PS, 2012, 'Differential expression of sirtuins in the aging rat brain [Poster]', Vancouver, Canada, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012