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Associate Professor Orin Chisholm
Adjunct Associate Professor

Associate Professor Orin Chisholm

BSc (Hons) (USyd), GCULT (UNSW), PhD (USyd)

Medicine & Health
School of Biomedical Sciences
E-mail
o.chisholm@unsw.edu.au
  • Book Chapters | 2023
    Chisholm O, 2023, 'Regulatory Landscape in Australia and New Zealand', in Handbook of Cell and Gene Therapy: From Proof-of-Concept through Manufacturing to Commercialization, pp. 233 - 242, http://dx.doi.org/10.1201/9781003285069-15
    Book Chapters | 2023
    Chisholm O, 2023, 'Training Approaches to Build Cell and Gene Therapy Workforce Capacity', in Handbook of Cell and Gene Therapy: From Proof-of-Concept through Manufacturing to Commercialization, pp. 175 - 182, http://dx.doi.org/10.1201/9781003285069-10
    Book Chapters | 2021
    Chisholm O; Carter M, 2021, 'Authorization Procedures for Pharmaceutical Products', in Hall G (ed.), Fundamentals of International Regulatory Affairs, Regulatory Affairs Professionals Society, USA, pp. 187 - 206, https://my.raps.org/online-store/merchandise-details/?id=0eeaf613-5fd3-eb11-ba5e-0003ff45124f&reload=timezone
    Book Chapters | 2018
    Chisholm O; Carter M, 2018, 'Authorization Procedures for Pharmaceutical Products', in Jones P (ed.), Fundamentals of International Regulatory Affairs, edn. 4, Regulatory Affairs Professional Society, USA, pp. 91 - 108
    Book Chapters | 2017
    Chisholm OT, 2017, 'Authorisation procedures for pharmaceutical products', in Jones P (ed.), Fundamentals of international regulatory affairs, edn. 3, RAPS, MD, USA, pp. 69 - 80, https://www.raps.org/ProductDetail.aspx?ProductId=131091030
  • Journal articles | 2023
    Chisholm O; Critchley H, 2023, 'Future directions in regulatory affairs', Frontiers in Medicine, 9, http://dx.doi.org/10.3389/fmed.2022.1082384
    Journal articles | 2023
    Yoffe A; Liu J; Smith G; Chisholm O, 2023, 'A Survey of Industry Perceptions of Facilitated Regulatory Pathways in Drug Development in Australia', Pharmaceutical Medicine, 37, pp. 385 - 394, http://dx.doi.org/10.1007/s40290-023-00483-x
    Journal articles | 2023
    Yoffe A; Liu J; Smith G; Chisholm O, 2023, 'Regulatory Reform Outcomes and Accelerated Regulatory Pathways for New Prescription Medicines in Australia', Therapeutic Innovation and Regulatory Science, 57, pp. 271 - 286, http://dx.doi.org/10.1007/s43441-022-00465-2
    Journal articles | 2022
    Chisholm O; Sharry P; Phillips L, 2022, 'Multi-Criteria Decision Analysis for Benefit-Risk Analysis by National Regulatory Authorities', Frontiers in Medicine, 8, http://dx.doi.org/10.3389/fmed.2021.820335
    Journal articles | 2022
    Volckmar X; Vallejo M; Bertoldo MJ; Nguyen QN; Handelsman DJ; Chisholm O; Anazodo A, 2022, 'Oncofertility Information Available for Recently Approved Novel Non Cytotoxic and Immunotherapy Oncology Drugs', Clinical Pharmacology and Therapeutics, 111, pp. 382 - 390, http://dx.doi.org/10.1002/cpt.2254
    Journal articles | 2020
    Shaw B; Chisholm O, 2020, 'Creeping Through the Backdoor: Disruption in Medicine and Health', Frontiers in Pharmacology, 11, http://dx.doi.org/10.3389/fphar.2020.00818
    Journal articles | 2019
    Chisholm O, 2019, 'Curriculum Transformation: From Didactic to Competency-Based Programs in Pharmaceutical Medicine', Frontiers in Pharmacology, 10, pp. 278 - 278, http://dx.doi.org/10.3389/fphar.2019.00278
    Journal articles | 2019
    Chisholm O, 2019, 'New Zealand’s new regulatory regime for therapeutic products', Regulatory Focus, https://www.raps.org/news-and-articles/news-articles/2019/3/new-zealands-new-regulatory-regime-for-therapeuti
    Journal articles | 2019
    Chisholm O, 2019, 'Professional Development: Benefits of Obtaining Professional Qualifications', Regulatory Focus, https://www.raps.org/news-and-articles/news-articles/2019/8/professional-development-benefits-of-obtaining-pr
    Journal articles | 2019
    Shaw B; Chisholm O, 2019, 'Australia's National Medicines Policy is outdated and in need of review', Medical Journal of Australia, 211, pp. 252 - 254, http://dx.doi.org/10.5694/mja2.50268
    Journal articles | 2018
    Allen GM; Chisholm O, 2018, 'Postgraduate Education in Pharmaceutical Medicine in Australia: Evaluation and Evolution to a Global Program Over 20 Years.', Therapeutic Innovation & Regulatory Science, pp. 1 - 7, http://dx.doi.org/10.1177/2168479018793129
    Journal articles | 2017
    Chisholm O, 2017, 'Program transformation: reimagining distance education in the digital world', Research and Development in Higher Education: Curriculum Transformation, 40, pp. 61 - 72, http://www.herdsa.org.au/research-and-development-higher-education-vol-40-61
    Journal articles | 2017
    Dauti A; Gerstl B; Chong S; Chisholm O; Anazodo A, 2017, 'Improvements in Clinical Trials Information Will Improve the Reproductive Health and Fertility of Cancer Patients', Journal of Adolescent and Young Adult Oncology, 6, pp. 235 - 269, http://dx.doi.org/10.1089/jayao.2016.0084
    Journal articles | 2015
    Chisholm OT, 2015, 'Proposed changes to US therapeutic products regulation', The Source Document, pp. 7 - 9
    Journal articles | 2013
    Badolato J; Chisholm OT; Holmes M, 2013, 'ARCS Australia University Partnerships.', The Source Document, pp. 34 - 34
    Journal articles | 2002
    Marsh IB; Whittington RJ; O''Rourke B; Hyatt AD; Chisholm OT, 2002, 'Rapid differentiation of Australian, European and American ranaviruses based on variation in major capsid protein gene sequence.', Molecular and Cellular Probes, 16, pp. 137 - 151, http://dx.doi.org/10.1006/mcpr.2001.0400
    Journal articles | 2001
    Ryan GR; Dai X-M; Dominguez MG; Tong W; Chuan F; Chisholm OT; Russell RG; Pollard JW; Stanley ER, 2001, 'Rescue of the colony stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1op/Csf1op) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis', Blood, 98, pp. 74 - 84, http://dx.doi.org/10.1182/blood.V98.1.74
    Journal articles | 2001
    Sungaran R; Chisholm OT, 2001, 'Thrombopoietin gene regulation – a review', Haematology, 6, pp. 41 - 46, http://dx.doi.org/10.1080/10245332.2001.11746551
    Journal articles | 2000
    Sungaran R; Chisholm OT; Markovic B; Khachigian LM; Tanaka Y; Chong BH, 2000, 'The role of platelet ?-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cells.', Blood, 95, pp. 3094 - 3101
    Journal articles | 1999
    Holmes ML; Turner J; Fox A; Chisholm OT; Crossley M; Chong BH, 1999, 'hFOG-2, a novel zinc finger protein, binds the corepressor mCtBP2 and modulates GATAmediated activation', The Journal of Biological Chemistry, 274, pp. 23491 - 23498, http://dx.doi.org/10.1074/jbc.274.33.23491
    Journal articles | 1996
    Cohen P; Chisholm OT; Arceci RJ; Stanley R; Pollard JW, 1996, 'Absence of colony stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects.', Biology of Reproduction, 55, pp. 310 - 317, http://dx.doi.org/10.1095/biolreprod55.2.310
    Journal articles | 1995
    Chang M; Stanley ER; Khalili H; Chisholm OT; Pollard JW, 1995, 'Osteopetrotic (op/op) mice deficient in macrophages have the ability to mount a normal T-cell-dependent immune response.', Cellular Immunology, 162, pp. 146 - 152, http://dx.doi.org/10.1006/cimm.1995.1062
    Journal articles | 1994
    CHISHOLM O; BERTONCELLO I, 1994, 'ALPHA-4-BETA-1 INTEGRIN EXPRESSION ON SUBSETS OF HEMATOPOIETIC STEM-CELLS', JOURNAL OF CELLULAR BIOCHEMISTRY, pp. 10 - 10, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994MV41200025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1994
    Cecchini ; Dominguez MG; Mocci S; Wetterwald A; Felix R; Fleisch H; Chisholm OT; Hofstetter W; Pollard JW; Stanley R, 1994, 'Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse.', Development, 120, pp. 1357 - 1372
    Journal articles | 1993
    Begg ; Radley JM; Pollard JW; Chisholm OT; Stanley R; Bertoncello I, 1993, 'Delayed haematopoietic development in osteopetrotic (op/op) mice.', Journal of Experimental Medicine, 177, pp. 237 - 242, http://dx.doi.org/10.1084/jem.177.1.237
    Journal articles | 1993
    CHISHOLM O; BERTONCELLO I, 1993, 'DOES EXPRESSION OF THE ALPHA-4-BETA-1 INTEGRIN CHANGE WITH THE PROLIFERATIVE AND DIFFERENTIATIVE CAPACITY OF MURINE PRIMITIVE HEMATOPOIETIC STEM-CELLS', JOURNAL OF LEUKOCYTE BIOLOGY, pp. 101 - 101, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500405&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1992
    BEGG SK; RADLEY JM; POLLARD JW; CHISHOLM O; STANLEY ER; BERTONCELLO I, 1992, 'MACROPHAGE DEVELOPMENT, AND AGE-RELATED-CHANGES IN HEMATOPOIESIS, IN CSF-1 DEFICIENT OSTEOPETROTIC (OP/OP) MICE', EXPERIMENTAL HEMATOLOGY, 20, pp. 826 - 826, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JA73400461&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1992
    Chisholm OT; Stapleton P; Symonds G, 1992, 'Constitutive expression of exogenous myc in myelomonocytic cells: acquisition of a more transformed phenotype and inhibition of differentiation induction.', Oncogene, 7, pp. 1827 - 1836
    Journal articles | 1992
    Chisholm OT; Symonds G, 1992, 'An in vitro fibroblast model system to study myc-driven tumour progression.', International Journal of Cancer, 51, pp. 149 - 158, http://dx.doi.org/10.1002/ijc.2910510126
    Journal articles | 1992
    Pollard JW; Arceci RJ; Chisholm O; Daiter E; Pampfer S; Stanley ER; Wiktor-Jedrzejczak W, 1992, 'Colony-stimulating factor-1 in the regulation of placental development', Journal of Cellular Biochemistry -Supplement-, 16F, pp. 75 - 75
    Journal articles | 1992
    Stanley ER; Wiktor-Jedrzejczak W; Pollard JW; Hunt JS; Chisholm O; Price LK, 1992, 'Biology and action of colony stimulating factor-1.', Journal of Cellular Biochemistry -Supplement-, 16C, pp. 57 - 57
    Journal articles | 1991
    Bonham L; Kwok J; Chisholm OT; Symonds G, 1991, 'Inducible transformation of fibroblasts using a metallothionein-v-myc gene construct.', Oncogene, 6, pp. 1073 - 1077
    Journal articles | 1989
    Symonds G; Bonham L; Chisholm OT; Miller M; Stapleton P; Takayama Y, 1989, 'The use of retroviral vectors to study cell transformation and malignancy.', Transplantation Proceedings, 21, pp. 61 - 64
    Journal articles | 1988
    Chisholm OT; Symonds G, 1988, 'Transfection of myeloid cell lines using polybrene/DMSO', Nucleic Acids Research, 16, pp. 2352, http://dx.doi.org/10.1093/nar/16.5.2352
    Journal articles | 1985
    Barry RD; Cowley JA; Chisholm OT; Richards SG, 1985, 'Structural and antigenic properties of human parainfluenza viruses', Virus Research, 3, pp. 78 - 78, http://dx.doi.org/10.1016/0168-1702(85)90408-3
  • Conference Presentations | 2018
    Pfeiffer J; Naraynassamy C; Chisholm O, 2018, 'Experiences of developing a PLuS Alliance course: pharmaceutical global regulatory affairs leadership', presented at King's Online & PLuS Alliance Conference 2018, London, 10 September 2018 - 12 September 2018
    Conference Presentations | 2017
    Chisholm O, 2017, 'Communities of practice in pharmaceutical medicine', presented at UNSW Learning and Teaching Forum – Educational Excellence: Transforming Futures, UNSW, 01 November 2017 - 01 November 2017
    Conference Presentations | 2017
    Chisholm O, 2017, 'Digital Uplift: Pharmaceutical Medicine Program', presented at Faculty of Medicine Learning and Teaching Forum, UNSW, 01 December 2017 - 01 December 2017, https://staff.med.unsw.edu.au/annual-learning-and-teaching-forum
    Conference Presentations | 2017
    Chisholm O, 2017, 'Program transformation: reimagining distance education in the digital world.', presented at Higher Education Research and Development Society of Australasia Conference, Sydney, 28 June 2017 - 30 June 2017
    Conference Presentations | 2017
    Dauti A; Gerstl B; Chong S; Chisholm O; Anazodo AC, 2017, 'What information do cancer clinical trial protocols include on the reproductive risk of treatment and oncofertility management?"', presented at 2017 Southern California Conferences for Undergraduate Research, Cal Poly Pomona, California, 18 November 2017 - 18 November 2017
    Conference Posters | 2016
    Chisholm OT; Gomes L; Thai T; Nixdorf S; Williams R; Clayphan A; Vigentini L; Zhang C; Zhao L; King M; Ford C, (ed.), 2016, 'Empowering Online Learners Using Assessment and Feedback', UNSW, presented at Towards 2025: Inspiring Learning, UNSW, 31 October 2016 - 31 October 2016
    Conference Posters | 2016
    Chisholm OT, (ed.), 2016, 'Program transformation: reimagining education in the digital world', UNSW, pp. 22 - 22, presented at Towards 2025: Inspiring Learning, UNSW, 31 October 2016 - 31 October 2016, https://teaching.unsw.edu.au/forum
    Conference Posters | 2016
    Dauti A; Gerstl B; Chong S; Chisholm O; Anazodo A, 2016, 'What information do cancer clinical trial protocols include on the reproductive risk of treatment and oncofertility management?', Chicago USA, presented at 10th Annual Oncofertility Consortium Conference, Chicago USA, 01 November 2016 - 03 November 2016
    Conference Presentations | 2016
    Ford C; Chisholm O; Gomes L, 2016, 'The Hope and Hype of the Genetic Revolution: Reflections on UNSW Medicine's First MOOC', presented at Connections Seminar Series, UNSW Australia, UNSW Australia, 19 May 2016 - 19 May 2016
    Conference Presentations | 2016
    Nixdorf S; Chisholm OT; Gomes L; Ford C, 2016, 'Student Engagement in the Personalised Medicine MOOC: Does the Learning Platform Matter?', presented at UNSW Medicine Learning and Teaching Forum, UNSW, Sydney, 07 December 2016 - 07 December 2016
    Conference Posters | 2015
    Chisholm OT; Parisio M; Heaton A; Brown D; Gunning P, (eds.), 2015, 'Blended strategies for learning about medicines development', UNSW, pp. 74 - 75, presented at UNSW Learning and Teaching Forum - Blended Learning: Past, Present and Future, UNSW, 16 October 2015 - 16 October 2015
    Conference Presentations | 2015
    Chisholm OT, 2015, 'Career Choices', presented at APSA-ASCEPT Joint Scientific Meeting 2015, Hobart. Tasmania, Australia, 29 November 2015 - 02 December 2015, http://www.asceptasm.com/
    Conference Presentations | 2015
    Chisholm OT, 2015, 'Online training for medical affairs professionals in China', presented at China Medical Affairs Summit, Shanghai, China, 17 June 2015 - 19 June 2015, http://www.chinamedicalaffairs.com/
    Conference Posters | 2015
    Chisholm OT, 2015, 'Teaching Cancer Therapeutics in a Postgraduate Masters Program in Pharmaceutical Medicine', Hobart, Tasmania, Australia, presented at APSA-ASCEPT Joint Scientific Meeting 2015, Hobart, Tasmania, Australia, 29 November 2015 - 02 December 2015, http://www.asceptasm.com/
    Conference Presentations | 2015
    Ford C; Chisholm OT; Gomes L, 2015, 'Hope and Hype: Reflections on UNSW Medicine's First MOOC', presented at 2015 UNSW Medicine Learning and Teaching Forum, UNSW, Sydney, NSW, Australia, 02 December 2015 - 02 December 2015, https://med.unsw.edu.au/annual-learning-and-teaching-forum
    Conference Presentations | 2014
    Chisholm O; Nixdorf S; Williams R; Ford C, 2014, 'Reflections on the development of an open online course', presented at UNSW Medicine Learning and Teaching Forum 2014, UNSW Australia, 10 December 2014 - 10 December 2014, http://med.unsw.edu.au/annual-learning-and-teaching-forum
    Conference Posters | 2014
    Elms J; Chisholm OT, (eds.), 2014, 'Using a medicine Case Study Matrix for self-paced, self-directed learning in a postgraduate Cancer Therapeutics course', UNSW, pp. 33 - 34, presented at UNSW Learning and Teaching Forum, UNSW, 08 October 2014 - 08 October 2014, http://teaching.unsw.edu.au/forum
    Other | 2013
    Chisholm OT, 2013, Submission on discussion paper “Description of a possible joint regulatory scheme for therapeutic products under ANZTPA”, http://www.anztpa.org/consultation/consult-anztpa-scheme-130108-submissions.htm, , http://www.anztpa.org/pdf/submissions/consult-anztpa-scheme-130108-submission-unsw.pdf
    Conference Papers | 1999
    Chisholm O; Fahmy R; Tao H; Holmes M; Chong B, 1999, 'Transcription factor and cell surface protein expression during megakaryocyte differentiation.', in EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, pp. 102 - 102, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000081030100250&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Sungaran R; Markovic B; Chong BH, 1999, 'The regulation of thrombopoietin mRNA expression - an in vitro and in vivo study', in Haematology Society of Australia and New Zealand - Annual Scientific Meeting, AMER SOC HEMATOLOGY, Hobart, pp. 39A - 39A, presented at Haematology Society of Australia and New Zealand - Annual Scientific Meeting, Hobart, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790300211&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 1999
    Yang M; Hogg PJ; Chisholm OT; Li K; Chesterman CN; Chong BH, 1999, 'TSP1 inhibits PEG-rHuMGDF-induced mega karyocytopoiesis via TSP/TSP receptor interaction.', in BLOOD, AMER SOC HEMATOLOGY, pp. 41A - 41A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790300218&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Yang M; Li K; Lam AC; Chui CMY; Yuen PMP; Chisholm OT; Chesterman CN; Chong BH, 1999, 'PDGF indirectly enhanced granulopoiesis.', in BLOOD, AMER SOC HEMATOLOGY, pp. 46B - 46B, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083790700200&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 1995
    Chisholm O; O'Connell P; Bertoncello I; Hapel A, 1995, 'Adhesion-dependent signalling in haematopoietic progenitor cell lines.', presented at Postgraduate Committee in Medicine 1995 Scientific Meeting, Canberra, -