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Adjunct Professor

Professor Paul De Souza

Medicine & Health
School of Clinical Medicine

Research Interests:
As a translational cancer researcher I am interested in applying sound biological and pharmacological principles to overcome the 'Valley of Death' in Drug Development. I focus on translating preclinical data into early Phase clinical trials of novel treatments, and discovering novel biomarkers (especially through liquid biopsy) that may help predict response or resistance to treatment: bench to bedside, and back to bench research. Individual cancers of interest include genitourinary, especially prostate, and brain tumours.

Broad Research Areas:
Cancer, Clinical Research, Cell Biology and Gene Regulation, Lipids, Pharmacology

Qualifications:
BScMed MB BS MPH Syd, PhD UNSW, FRACP

Society Memberships & Professional Activities:
ASCO, AACR, MOG, COSA

Specific Research Keywords:
Prostate Cancer, Brain Cancer, Cancer Drug Development and Pharmacology, Renal Cancer, Bladder Cancer
Phone
+61-2-85569300
  • Book Chapters | 2021
    Po JW; Ma Y; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'PD-L1 Detection on Circulating Melanoma Cells', in Melanoma: Methods and Protocols, United States, pp. 223 - 233, http://dx.doi.org/10.1007/978-1-0716-1205-7_17
    Book Chapters | 2021
    Po JW; Ma Y; Luk AWS; Lynch D; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'Single-Cell Analysis of BRAFV600E and NRASQ61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells', in Melanoma: Methods and Protocols, United States, pp. 277 - 286, http://dx.doi.org/10.1007/978-1-0716-1205-7_21
    Book Chapters | 2016
    Po JW; Lynch D; de Souza P; Becker TM, 2016, 'Importance and Detection of Epithelial-to-Mesenchymal Transition (EMT) Phenotype in CTCs', in Xu K (ed.), TUMOR METASTASIS, INTECH EUROPE, pp. 241 - 256, http://dx.doi.org/10.5772/64342
    Book Chapters | 2012
    A C; Scott K; Bucci J; Greenfield H; Dong Q; de Souz PL, 2012, 'Dietary Manipulation for Therapeutic Effect in Prostate Cancer', in Cancer Prevention - From Mechanisms to Translational Benefits, InTech, http://dx.doi.org/10.5772/32620
  • Journal articles | 2023
    Gano C; Fatima S; Failes T; Arndt G; Sajinovic M; Mahns D; Saedisomeolia A; Coorssen J; Bucci J; DeSouza P; Vafaee F; Scott K, 2023, 'Anti-cancer potential of synergistic phytochemical combinations is influenced by the genetic profiles of prostate cancer cell lines', Frontiers in Nutrition, http://dx.doi.org/10.3389/fnut.2023.1119274
    Journal articles | 2023
    Gao B; Voskoboynik M; Cooper A; Wilkinson K; Hoon S; Hsieh CY; Cai S; Tian YE; Bao J; Ma N; Wang C; Zhang M; Li B; Guo M; Zhou R; Wang X; Xu C; de Souza P, 2023, 'A phase 1 dose-escalation study of the poly(ADP-ribose) polymerase inhibitor senaparib in Australian patients with advanced solid tumors', Cancer, 129, pp. 1041 - 1050, http://dx.doi.org/10.1002/cncr.34662
    Journal articles | 2023
    Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; de Souza P; Spring KJ, 2023, 'Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and Are Predictive of Response in Locally Advanced Rectal Cancer', Cancers, 15, http://dx.doi.org/10.3390/cancers15164184
    Journal articles | 2022
    Fatima S; Ma Y; Safrachi A; Haider S; Spring KJ; Vafaee F; Scott KF; Roberts TL; Becker TM; de Souza P, 2022, 'Harnessing Liquid Biopsies to Guide Immune Checkpoint Inhibitor Therapy', Cancers, 14, pp. 1669 - 1669, http://dx.doi.org/10.3390/cancers14071669
    Journal articles | 2022
    Hnit SST; Yao M; Xie C; Bi L; Wong M; Liu T; De Souza P; Li Z; Dong Q, 2022, 'Apigenin impedes cell cycle progression at G2 phase in prostate cancer cells', Discover Oncology, 13, http://dx.doi.org/10.1007/s12672-022-00505-1
    Journal articles | 2022
    Jeffreys SA; Becker TM; Khan S; Soon P; Neubauer H; de Souza P; Powter B, 2022, 'Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis', Frontiers in Endocrinology, 13, pp. 895729, http://dx.doi.org/10.3389/fendo.2022.895729
    Journal articles | 2022
    Khan T; Becker TM; Scott KF; Descallar J; de Souza P; Chua W; Ma Y, 2022, 'Prognostic and Predictive Value of Liquid Biopsy-Derived Androgen Receptor Variant 7 (AR-V7) in Prostate Cancer: A Systematic Review and Meta-Analysis', Frontiers in Oncology, 12, pp. 868031, http://dx.doi.org/10.3389/fonc.2022.868031
    Journal articles | 2022
    Khan T; Lock JG; Ma Y; Harman DG; de Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, 'Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells', Scientific Reports, 12, pp. 16159, http://dx.doi.org/10.1038/s41598-022-20079-w
    Journal articles | 2022
    Lai HC; Ho UY; James A; De Souza P; Roberts TL, 2022, 'RNA metabolism and links to inflammatory regulation and disease', Cellular and Molecular Life Sciences, 79, http://dx.doi.org/10.1007/s00018-021-04073-5
    Journal articles | 2022
    Rottey S; Clarke J; Aung K; Machiels JP; Markman B; Heinhuis KM; Millward M; Lolkema M; Patel SP; De Souza P; Duca M; Curigliano G; Santoro A; Koyama T; Brown M; Vezina H; He C; Siu-Chung Chu Q, 2022, 'Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors', Clinical Cancer Research, 28, pp. 95 - 105, http://dx.doi.org/10.1158/1078-0432.CCR-21-1181
    Journal articles | 2022
    Sareen H; Ma Y; Becker TM; Roberts TL; de Souza P; Powter B, 2022, 'Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis', International journal of molecular sciences, 23, http://dx.doi.org/10.3390/ijms23168835
    Journal articles | 2022
    Young FP; Becker TM; Nimir M; Opperman T; Chua W; Balakrishnar B; de Souza P; Ma Y, 2022, 'Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11010257
    Journal articles | 2022
    de Souza PL; Aslan P; Clark W; Nour R; de Silva S, 2022, 'RESIRT: A Phase 1 Study of Selective Internal Radiation Therapy Using Yttrium-90 Resin Microspheres in Patients With Primary Renal Cell Carcinoma', Clinical Genitourinary Cancer, 20, pp. 442 - 451, http://dx.doi.org/10.1016/j.clgc.2022.05.006
    Journal articles | 2021
    Ardern-Holmes S; White C; Bahure S; So S; McCowage G; Hovey E; Troon S; De Souza P; Simes J; Slancar M; Dexter M; Wong M, 2021, 'The Effect of Bevacizumab on Vestibular Schwannoma Related to Neurofibromatosis Type 2', Australasian Journal of Neuroscience, 31, pp. 5 - 14, http://dx.doi.org/10.21307/ajon-2021-002
    Journal articles | 2021
    Cameron B; Webber K; Li H; Bennett BK; Boyle F; de Souza P; Wilcken N; Lynch J; Friedlander M; Goldstein D; Lloyd AR, 2021, 'Genetic associations of fatigue and other symptoms following breast cancer treatment: A prospective study', Brain, Behavior, and Immunity - Health, 10, pp. 100189, http://dx.doi.org/10.1016/j.bbih.2020.100189
    Journal articles | 2021
    Ding PN; Roberts TL; Chua W; Becker TM; Caixeiro N; de Souza P; Gao B; Lee CK; Itchins M; Westman H; Clarke S; Blinman P; Kao S; John T; Leal JL; Bray VJ, 2021, 'Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib', Translational Lung Cancer Research, 10, pp. 1623 - 1634, http://dx.doi.org/10.21037/tlcr-20-1125
    Journal articles | 2021
    Garrett C; Becker TM; Lynch D; Po J; Xuan W; Scott KF; De Souza P, 2021, 'Comparison of neutrophil to lymphocyte ratio and prognostic nutritional index with other clinical and molecular biomarkers for prediction of glioblastoma multiforme outcome', PLoS ONE, 16, http://dx.doi.org/10.1371/journal.pone.0252614
    Journal articles | 2021
    Hnit SST; Ding R; Bi L; Xie C; Yao M; De Souza P; Xu L; Li Z; Dong Q, 2021, 'Agrimol B present in Agrimonia pilosa Ledeb impedes cell cycle progression of cancer cells through G0 state arrest', Biomedicine and Pharmacotherapy, 141, pp. 111795, http://dx.doi.org/10.1016/j.biopha.2021.111795
    Journal articles | 2021
    Lai HC; James A; Luff J; De Souza P; Quek H; Ho U; Lavin MF; Roberts TL, 2021, 'Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages', Journal of Leukocyte Biology, 109, pp. 593 - 603, http://dx.doi.org/10.1002/JLB.2AB0420-151RR
    Journal articles | 2021
    Lee DH; Roohullah A; Cho BC; Lemech C; de Souza P; Millward M; Choi J; Park KE; Lee M; Kim Y; Park S; Lee J; Kim J; Shin YK; Han J-Y, 2021, 'Phase I dose-escalation study to evaluate safety and clinical activity of c-MET inhibitor ABN401 in patients with advanced solid tumor', ANNALS OF ONCOLOGY, 32, pp. S1029 - S1030, http://dx.doi.org/10.1016/j.annonc.2021.08.1958
    Journal articles | 2021
    Lee DH; Roohullah A; Cho BC; Lemech CR; de Souza PL; Millward M; Choi JY; Park KE; Lee M; Kim Y; Shin Y; Han J-Y, 2021, 'Trial in progress: A phase 1-2 multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of ABN401 in patients with advanced solid tumors.', JOURNAL OF CLINICAL ONCOLOGY, 39, http://dx.doi.org/10.1200/JCO.2021.39.15_suppl.TPS3157
    Journal articles | 2021
    Nabil WNN; Xi Z; Song Z; Jin L; Zhang XD; Zhou H; De Souza P; Dong Q; Xu H, 2021, 'Towards a framework for better understanding of quiescent cancer cells', Cells, 10, pp. 1 - 19, http://dx.doi.org/10.3390/cells10030562
    Journal articles | 2021
    Piha-Paul SA; Thein KZ; De Souza P; Kefford R; Gangadhar T; Smith C; Schuster S; Zamboni WC; Dees CE; Markman B, 2021, 'First‐in‐human, phase I/IIa study of CRLX301, a nanoparticle drug conjugate containing docetaxel, in patients with advanced or metastatic solid malignancies', Investigational New Drugs, 39, pp. 1047 - 1056, http://dx.doi.org/10.1007/s10637-021-01081-x
    Journal articles | 2021
    Powter B; Jeffreys SA; Sareen H; Cooper A; Brungs D; Po J; Roberts T; Koh ES; Scott KF; Sajinovic M; Vessey JY; de Souza P; Becker TM, 2021, 'Human TERT promoter mutations as a prognostic biomarker in glioma', Journal of Cancer Research and Clinical Oncology, 147, pp. 1007 - 1017, http://dx.doi.org/10.1007/s00432-021-03536-3
    Journal articles | 2021
    Razdan A; Main NM; Chiu V; Shackel NA; de Souza P; Bryant K; Scott KF, 2021, 'Targeting the eicosanoid pathway in hepatocellular carcinoma', AMERICAN JOURNAL OF CANCER RESEARCH, 11, pp. 2456 - 2476, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667209700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2021
    Roohullah A; Ganju V; Zhang F; Zhang L; Yu T; Wilkinson K; Cooper A; de Souza P, 2021, 'First-in-human phase 1 dose escalation study of HX009, a novel recombinant humanized anti-PD-1 and CD47 bispecific antibody, in patients with advanced malignancies.', JOURNAL OF CLINICAL ONCOLOGY, 39, http://dx.doi.org/10.1200/JCO.2021.39.15_suppl.2517
    Journal articles | 2021
    Scott KF; Mann TJ; Fatima S; Sajinovic M; Razdan A; Kim RR; Cooper A; Roohullah A; Bryant KJ; Gamage KK; Harman DG; Vafaee F; Graham GG; Church WB; Russell PJ; Dong Q; de Souza P, 2021, 'Human group iia phospholipase A2 —three decades on from its discovery', Molecules, 26, pp. 7267 - 7267, http://dx.doi.org/10.3390/molecules26237267
    Journal articles | 2020
    Ackland SP; Michael M; de Souza P; Martin JH; Clarke SJ; Francis K; Karapetis CS; Gurney H, 2020, 'Science and art of anticancer drug dosing: nine steps to personalised therapy', Internal Medicine Journal, 50, pp. 992 - 996, http://dx.doi.org/10.1111/imj.14948
    Journal articles | 2020
    Aghajani MJ; Yang T; Schmitz U; James A; McCafferty CE; de Souza P; Niles N; Roberts TL, 2020, 'Epithelial-to-mesenchymal transition and its association with PD-L1 and CD8 in thyroid cancer', Endocrine Connections, 9, pp. 1028 - 1041, http://dx.doi.org/10.1530/EC-20-0268
    Journal articles | 2020
    Bi L; Xie C; Jiao L; Jin S; Hnit SST; Mu Y; Wang Y; Wang Q; Ge G; Wang Y; Zhao X; Shi X; Kang Y; De Souza P; Liu T; Zhou J; Xu L; Dong Q, 2020, 'CPF impedes cell cycle re-entry of quiescent lung cancer cells through transcriptional suppression of FACT and c-MYC', Journal of Cellular and Molecular Medicine, 24, pp. 2229 - 2239, http://dx.doi.org/10.1111/jcmm.14897
    Journal articles | 2020
    Broom A; Parker R; Raymond S; Kirby E; Lewis S; Kokanović R; Adams J; de Souza P; Woodland L; Wyld D; Lwin Z; Koh ES, 2020, 'The (Co)Production of Difference in the Care of Patients With Cancer From Migrant Backgrounds', Qualitative Health Research, 30, pp. 1619 - 1631, http://dx.doi.org/10.1177/1049732320930699
    Journal articles | 2020
    Hnit SST; Yao M; Xie C; Ge G; Bi L; Jin S; Jiao L; Xu L; Long L; Nie H; Jin Y; Rogers L; Suchowerska N; Wong M; Liu T; De Souza P; Li Z; Dong Q, 2020, 'Transcriptional regulation of G2/M regulatory proteins and perturbation of G2/M Cell cycle transition by a traditional Chinese medicine recipe', Journal of Ethnopharmacology, 251, http://dx.doi.org/10.1016/j.jep.2019.112526
    Journal articles | 2020
    Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Chua W; Ng W; Lee M; Roberts TL; de Souza P; Lee CS, 2020, 'Aberrant expression of RAD52, its prognostic impact in rectal cancer and association with poor survival of patients', International Journal of Molecular Sciences, 21, http://dx.doi.org/10.3390/ijms21051768
    Journal articles | 2020
    Jeffreys SA; Powter B; Balakrishnar B; Mok K; Soon P; Franken A; Neubauer H; de Souza P; Becker TM, 2020, 'Endocrine Resistance in Breast Cancer: The Role of Estrogen Receptor Stability', Cells, 9, http://dx.doi.org/10.3390/cells9092077
    Journal articles | 2020
    Kato H; de Souza P; Kim SW; Lickliter JD; Naito Y; Park K; Kumar S; Mugundu GM; Bang YJ, 2020, 'Safety, Pharmacokinetics, and Clinical Activity of Adavosertib in Combination with Chemotherapy in Asian Patients with Advanced Solid Tumors: Phase Ib Study', Targeted Oncology, 15, pp. 75 - 84, http://dx.doi.org/10.1007/s11523-020-00701-5
    Journal articles | 2020
    Khan T; Scott KF; Becker TM; Lock J; Nimir M; Ma Y; De Souza P, 2020, 'The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?', Prostate Cancer, 2020, pp. 7938280, http://dx.doi.org/10.1155/2020/7938280
    Journal articles | 2020
    Lynch D; Powter B; Po JW; Cooper A; Garrett C; Koh ES; Sheridan M; van Gelder J; Darwish B; Mckechnie S; Bazina R; Jaeger M; Roberts TL; de Souza P; Becker TM, 2020, 'Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting', Applied Sciences (Switzerland), 10, pp. 3338 - 3338, http://dx.doi.org/10.3390/app10093338
    Journal articles | 2020
    Reardon DA; Brandes AA; Omuro A; Mulholland P; Lim M; Wick A; Baehring J; Ahluwalia MS; Roth P; Bähr O; Phuphanich S; Sepulveda JM; De Souza P; Sahebjam S; Carleton M; Tatsuoka K; Taitt C; Zwirtes R; Sampson J; Weller M, 2020, 'Effect of Nivolumab vs Bevacizumab in Patients with Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial', JAMA Oncology, 6, pp. 1003 - 1010, http://dx.doi.org/10.1001/jamaoncol.2020.1024
    Journal articles | 2020
    Sareen H; Garrett C; Lynch D; Powter B; Brungs D; Cooper A; Po J; Koh ES; Vessey JY; McKechnie S; Bazina R; Sheridan M; van Gelder J; Darwish B; Jaeger M; Roberts TL; De Souza P; Becker TM, 2020, 'The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients', Cancers, 12, pp. 1 - 16, http://dx.doi.org/10.3390/cancers12071831
    Journal articles | 2020
    Tjokrowidjaja A; Goldstein D; Hudson HM; Lord SJ; Gebski V; Clarke S; de Souza P; Motzer RJ; Lee CK, 2020, 'The impact of neutrophil-lymphocyte ratio on risk reclassification of patients with advanced renal cell cancer to guide risk-directed therapy', Acta Oncologica, 59, pp. 20 - 27, http://dx.doi.org/10.1080/0284186X.2019.1656342
    Journal articles | 2020
    Toh JWT; Lim SH; MacKenzie S; de Souza P; Bokey L; Chapuis P; Spring KJ, 2020, 'Association Between Microsatellite Instability Status and Peri-Operative Release of Circulating Tumour Cells in Colorectal Cancer', Cells, 9, http://dx.doi.org/10.3390/cells9020425
    Journal articles | 2020
    Wimmer M; Zauner R; Ablinger M; Pinõ´ n-Hofbauer J; Guttmann-Gruber C; Reisenberger M; Lettner T; Niklas N; Proell J; Sajinovic M; De Souza P; Hainzl S; Kocher T; Murauer EM; Bauer JW; Strunk D; Reichelt J; Mellick AS; Wally V, 2020, 'A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas', Cell Communication and Signaling, 18, pp. 61, http://dx.doi.org/10.1186/s12964-020-00550-9
    Journal articles | 2020
    de Souza P; Gao B; Voskoboynik M; Wilkinson K; Cooper A; Hoon S-N; Palmieri D; Cai S; Tian YE; Hsieh C-Y; Ma N; Xu C; Chen Y; Yang S; Zhang S, 2020, '574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours', Annals of Oncology, 31, pp. S490 - S490, http://dx.doi.org/10.1016/j.annonc.2020.08.688
    Journal articles | 2020
    de Souza PL; Capp AL; Chikhladze N; Mezvrishvili Z; Messina M; Mautner G, 2020, 'Phase I study of a novel S1P inhibitor, NOX66, in combination with radiotherapy in patients with metastatic castration-resistant prostate cancer.', Journal of Clinical Oncology, 38, pp. 5533 - 5533, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5533
    Journal articles | 2019
    Aghajani MJ; Cooper A; McGuire H; Jeffries T; Saab J; Ismail K; de Souza P; Bray V; Fazekas de St Groth B; Niles N; Roberts TL, 2019, 'Pembrolizumab for anaplastic thyroid cancer: a case study', Cancer Immunology, Immunotherapy, 68, pp. 1921 - 1934, http://dx.doi.org/10.1007/s00262-019-02416-7
    Journal articles | 2019
    Basch EM; Scholz M; de Bono JS; Vogelzang N; de Souza P; Marx G; Vaishampayan U; George S; Schwarz JK; Antonarakis ES; O'Sullivan JM; Kalebasty AR; Chi KN; Dreicer R; Hutson TE; Dueck AC; Bennett AV; Dayan E; Mangeshkar M; Holland J; Weitzman AL; Scher HI, 2019, 'Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint', European Urology, 75, pp. 929 - 937, http://dx.doi.org/10.1016/j.eururo.2018.11.033
    Journal articles | 2019
    Broom A; Kirby E; Kokonavic R; Woodland L; Wyld D; de Souza P; Koh S; Lwin Z, 2019, 'Individualising difference, negotiating culture: Intersections of biography and cancer care', Health, pp. 1363459319829192, http://dx.doi.org/10.1177/1363459319829192
    Journal articles | 2019
    Cao J; Zhang P; De Souza PL; Gao B; Voskoboynik M; Ji D; Shen W; Yang S; Zhou Y; Zhang R; Lickliter JD; Hoon S-N; Palmieri D; Cai S; Tian YE; Ma N; Xu C; Yang S; Zhang S; Xu B, 2019, 'Pooled analysis of phase I dose-escalation and dose cohort expansion studies of IMP4297, a novel PARP inhibitor, in Chinese and Australian patients with advanced solid tumors.', JOURNAL OF CLINICAL ONCOLOGY, 37, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.3059
    Journal articles | 2019
    Clingan PR; Ackland SP; Brungs D; de Souza P; Aghmesheh M; Garg MB; Ranson RD; Parker S; Jokela R; Ranson M, 2019, 'First-in-human phase I study of infusional and bolus schedules of Deflexifol, a novel 5-fluorouracil and leucovorin formulation, after failure of standard treatment', Asia-Pacific Journal of Clinical Oncology, 15, pp. 151 - 157, http://dx.doi.org/10.1111/ajco.13144
    Journal articles | 2019
    Ding PN; Becker T; Bray V; Chua W; Ma Y; Xu B; Lynch D; de Souza P; Roberts T, 2019, 'Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib', Thoracic Cancer, 10, pp. 1879 - 1884, http://dx.doi.org/10.1111/1759-7714.13154
    Journal articles | 2019
    Ding PN; Becker TM; Bray VJ; Chua W; Ma YF; Lynch D; Po J; Luk AWS; Caixeiro N; de Souza P; Roberts TL, 2019, 'The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study', Lung Cancer, 134, pp. 187 - 193, http://dx.doi.org/10.1016/j.lungcan.2019.06.021
    Journal articles | 2019
    Lim SHS; Ip E; Ng W; Chua W; Asghari R; Roohullah A; Descallar J; Henderson C; Spring K; de Souza P; King MT, 2019, 'Health-related quality of life during chemoradiation in locally advanced rectal cancer: Impacts and ethnic disparities', Cancers, 11, http://dx.doi.org/10.3390/cancers11091263
    Journal articles | 2019
    Naher S; Padinharakam S; Balakrishnar B; Chua W; Descallar J; Adams D; de Souza P; Harrison M; Lim S, 2019, 'Patterns of Presentation and Treatment Outcomes of Non–clear-cell Renal Cell Carcinoma and Sarcomatoid Renal Cell Carcinoma Patients in 2 Tertiary Referral Centers in Sydney, Australia', Clinical Genitourinary Cancer, 17, pp. e565 - e569, http://dx.doi.org/10.1016/j.clgc.2019.02.006
    Journal articles | 2019
    Nimir M; Ma Y; Jeffreys SA; Opperman T; Young F; Khan T; Ding P; Chua W; Balakrishnar B; Cooper A; Souza PD; Becker TM, 2019, 'Detection of AR-v7 in liquid biopsies of castrate resistant prostate cancer patients: A comparison of AR-v7 analysis in circulating tumor cells, circulating tumor RNA and exosomes', Cells, 8, http://dx.doi.org/10.3390/cells8070688
    Journal articles | 2019
    Panizza BJ; de Souza P; Cooper A; Roohullah A; Karapetis CS; Lickliter JD, 2019, 'Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46)', EBioMedicine, 50, pp. 433 - 441, http://dx.doi.org/10.1016/j.ebiom.2019.11.037
    Journal articles | 2019
    Po JW; Ma Y; Balakrishna B; Brungs D; Azimi F; De Souza P; Becker TM, 2019, 'Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status', PLoS ONE, 14, pp. e0211866, http://dx.doi.org/10.1371/journal.pone.0211866
    Journal articles | 2019
    Powderly J; Spira A; Gutierrez R; DiRenzo D; Udyavar A; Karakunnel JJ; Rieger A; Colabella J; Lai DW; de Souza P, 2019, 'Phase I evaluation of AB928, a novel dual adenosine receptor antagonist, combined with chemotherapy or AB122 (anti-PD-1) in patients (pts) with advanced malignancies', Annals of Oncology, 30, pp. v493 - v493, http://dx.doi.org/10.1093/annonc/mdz253.032
    Journal articles | 2019
    Singh P; de Souza P; Scott KF; Hall BM; Verma ND; Becker TM; Toh JWT; Sajinovic M; Spring KJ, 2019, 'Biomarkers in immune checkpoint inhibition therapy for cancer patients: what is the role of lymphocyte subsets and PD1/PD-L1?', Translational Medicine Communications, 4, http://dx.doi.org/10.1186/s41231-019-0032-9
    Journal articles | 2019
    Weller M; Reardon D; Brandes A; Sampson J; Mulholland P; Wick A; Baehring J; Ahluwalia M; Roth P; Bähr O; Phuphanich S; Sepulveda J; de Souza P; Sahebjam S; Potter V; Tatsuoka K; Taitt C; Zwirtes R; Omuro A; Lim M, 2019, 'ATIM-47. NIVOLUMAB VS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: EXPLORATORY ANALYSIS OF MGMT METHYLATION STATUS AND BASELINE CORTICOSTEROID USE', Neuro-Oncology, 21, pp. vi12 - vi12, http://dx.doi.org/10.1093/neuonc/noz175.045
    Journal articles | 2018
    Bi L; Xie C; Yao M; Thae Hnit SS; Vignarajan S; Wang Y; Wang Q; Xi Z; Xu H; Li Z; de Souza P; Tee A; Wong M; Liu T; Zhao X; Zhou J; Xu L; Dong Q, 2018, 'The histone chaperone complex FACT promotes proliferative switch of G0 cancer cells', International Journal of Cancer, 145, pp. 164 - 178, http://dx.doi.org/10.1002/ijc.32065
    Journal articles | 2018
    Brungs D; Aghmesheh M; de Souza P; Carolan M; Clingan P; Rose J; Ranson M, 2018, 'Safety and Efficacy of Oxaliplatin Doublet Adjuvant Chemotherapy in Elderly Patients With Stage III Colon Cancer', Clinical Colorectal Cancer, 17, pp. e549 - e555, http://dx.doi.org/10.1016/j.clcc.2018.05.004
    Journal articles | 2018
    Brungs D; Lynch D; Luk AWS; Minaei E; Ranson M; Aghmesheh M; Vine KL; Carolan M; Jaber M; De Souza P; Becker TM, 2018, 'Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer', World Journal of Gastroenterology, 24, pp. 810 - 818, http://dx.doi.org/10.3748/wjg.v24.i7.810
    Journal articles | 2018
    Campbell DH; Lund ME; Nocon AL; Cozzi PJ; Frydenberg M; De Souza P; Schiller B; Beebe-Dimmer JL; Ruterbusch JJ; Walsh BJ, 2018, 'Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0196017
    Journal articles | 2018
    Ding PN; Ma YF; Roberts TJ; Chua W; Bray VJ; Lynch D; Burke D; Souza PD; Becker TM, 2018, 'Droplet Digital PCR Based Detection of EGFR Mutations in Advanced Lung Cancer Patient Liquid Biopsies: A Comparison of Circulating Tumour DNA Extraction Kits', Journal of Molecular Biomarkers & Diagnosis, 09, http://dx.doi.org/10.4172/2155-9929.1000397
    Journal articles | 2018
    Harris BHL; Walsh JL; Neciunaite R; Manders P; Cooper A; De Souza P, 2018, 'Ring a ring o'roses, a patient with Kaposi's? Pazopanib, pazopanib, it might go away. Mediterranean (classic) Kaposi sarcoma responds to the tyrosine kinase inhibitor pazopanib after multiple lines of standard therapy', Clinical and Experimental Dermatology, 43, pp. 234 - 236, http://dx.doi.org/10.1111/ced.13302
    Journal articles | 2018
    Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Ng W; Lee M; de Souza P; Shin JS; Lee CS, 2018, 'Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis', BMC Cancer, 18, http://dx.doi.org/10.1186/s12885-018-4776-9
    Journal articles | 2018
    Po JW; Roohullah A; Lynch D; DeFazio A; Harrison M; Harnett PR; Kennedy C; de Souza P; Becker TM, 2018, 'Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin', Journal of Circulating Biomarkers, 7, http://dx.doi.org/10.1177/1849454418782617
    Journal articles | 2018
    Razdan A; de Souza P; Roberts TL, 2018, 'Role of microRNAs in treatment response in prostate cancer', Current Cancer Drug Targets, 18, pp. 929 - 944, http://dx.doi.org/10.2174/1568009618666180315160125
    Journal articles | 2018
    Roohullah A; Cooper A; Lomax AJ; Aung J; Barge A; Chow L; McHale M; Desai J; Whittle JR; Tran B; de Souza P; Horvath LG, 2018, 'A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers', Investigational New Drugs, 36, pp. 886 - 894, http://dx.doi.org/10.1007/s10637-018-0588-7
    Journal articles | 2018
    de Souza PL; Messina M; Minns I; Shavdia M; Chikhladze N; Kelly G, 2018, 'A phase 1 study of NOX66 in combination with carboplatin in patients with end stage solid tumours.', Journal of Clinical Oncology, 36, pp. 2585 - 2585, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.2585
    Journal articles | 2018
    de Souza PL; Wong S; Sewak S; Kotasek D; Keam B; Chung J; Erbeck N; Han J; Dezzani L; Ahmad Q; Mainwaring PN, 2018, 'Phase II study of sequential first-line pazopanib (PAZ) followed by everolimus (EVE) in patients (pts) with advanced or metastatic renal cell carcinoma (RCC) (CATChEz Study).', JOURNAL OF CLINICAL ONCOLOGY, 36, http://dx.doi.org/10.1200/JCO.2018.36.6_suppl.648
    Journal articles | 2017
    Ackland SP; Garg MB; Ranson M; Jokela R; Brungs D; Aghmesheh M; Tafreshi A; Ranson RD; Parker S; De Souza PL; Clingan PR, 2017, 'Deflexifol (a novel formulation of 5FU): Pharmacokinetics in a phase 1 trial in comparison to 5FU.', Journal of Clinical Oncology, 35, pp. 2530 - 2530, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2530
    Journal articles | 2017
    Aslan P; Clark W; Patel M; Vass J; Cade D; De Silva SJ; De Souza P, 2017, 'Renal function after selective internal radiation therapy (SIRT) with yttrium-90 (Y-90) resin microspheres in patients with primary renal cell carcinoma (RCC): The RESIRT study', European Urology Supplements, 16, pp. e630 - e631, http://dx.doi.org/10.1016/s1569-9056(17)30424-4
    Journal articles | 2017
    Aslan P; Clark W; Patel M; Vass J; Cade DN; de Silva SJ; de Souza PL, 2017, 'MP16-12 SELECTIVE INTERNAL RADIATION THERAPY (SIRT) WITH YTTRIUM-90 (Y-90) RESIN MICROSPHERES IN PATIENTS WITH PRIMARY RENAL CELL CARCINOMA (RCC): IMPACT ON RENAL FUNCTION AND QUALITY OF LIFE IN THE RESIRT STUDY', Journal of Urology, 197, http://dx.doi.org/10.1016/j.juro.2017.02.518
    Journal articles | 2017
    Brungs D; Aghmesheh M; de Souza P; Ng W; Chua W; Carolan M; Clingan P; Healey E; Rose J; Tubaro T; Ranson M, 2017, 'Sidedness is prognostic in locoregional colon cancer: An analysis of 9509 Australian patients', BMC Cancer, 17, http://dx.doi.org/10.1186/s12885-017-3255-z
    Journal articles | 2017
    Callari M; De Souza PL; Rawal A; Stenzel MH, 2017, 'The Effect of Drug Loading on Micelle Properties: Solid-State NMR as a Tool to Gain Structural Insight', Angewandte Chemie - International Edition, 56, pp. 8441 - 8445, http://dx.doi.org/10.1002/anie.201701471
    Journal articles | 2017
    Callari M; De Souza PL; Rawal A; Stenzel MH, 2017, 'The Effect of Drug Loading on Micelle Properties: Solid‐State NMR as a Tool to Gain Structural Insight', Angewandte Chemie, 129, pp. 8561 - 8565, http://dx.doi.org/10.1002/ange.201701471
    Journal articles | 2017
    Callari M; Wong S; Lu H; Aldrich-Wright J; De Souza P; Stenzel MH, 2017, 'Drug induced self-assembly of triblock copolymers into polymersomes for the synergistic dual-drug delivery of platinum drugs and paclitaxel', Polymer Chemistry, 8, pp. 6289 - 6299, http://dx.doi.org/10.1039/c7py01162h
    Journal articles | 2017
    Clark W; Aslan P; Patel M; Vass J; Cade D; de Silva S; De Souza P, 2017, 'The RESIRT study: feasibility and dosimetry considerations of selective internal radiation therapy (SIRT) using yttrium-90 (Y-90) resin microspheres in patients with primary renal cell carcinoma (RCC)', Journal of Vascular and Interventional Radiology, 28, pp. S164 - S164, http://dx.doi.org/10.1016/j.jvir.2016.12.1001
    Journal articles | 2017
    Clingan PR; Ackland SP; Ranson M; Brungs D; Aghmesheh M; Tafreshi A; Garg MB; Parker S; Henderson A; Jokela R; De Souza PL, 2017, 'Deflexifol (a novel formulation of 5FU): Phase 1 dose escalation study of infusional and bolus schedules after failure of standard treatment.', Journal of Clinical Oncology, 35, pp. 2529 - 2529, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2529
    Journal articles | 2017
    Clingan PR; Ackland SP; Ranson M; De Souza P; Tafreshi A; Aghmesheh M; Brungs D; Garg MB; Parker S; Jokela R, 2017, 'Phase 1 study of infusional or bolus deflexifol (a novel formulation of 5FU, folinic acid, and cyclodextrin) after failure of standard treatment.', Journal of Clinical Oncology, 35, pp. TPS812 - TPS812, http://dx.doi.org/10.1200/jco.2017.35.4_suppl.tps812
    Journal articles | 2017
    Del Re M; Fogli S; Derosa L; Massari F; De Souza P; Crucitta S; Bracarda S; Santini D; Danesi R, 2017, 'The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide', Cancer Treatment Reviews, 55, pp. 71 - 82, http://dx.doi.org/10.1016/j.ctrv.2017.03.001
    Journal articles | 2017
    Ho V; Chung L; Singh A; Lea V; Revoltar M; Lim SH; Tut TG; Ng W; Lee M; de Souza P; Shin JS; Lee CS, 2017, 'Early postoperative low expression of RAD50 in rectal cancer patients associates with disease-free survival', Cancers, 9, http://dx.doi.org/10.3390/cancers9120163
    Journal articles | 2017
    Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, 18, http://dx.doi.org/10.3390/ijms18051047
    Journal articles | 2017
    Reardon DA; Omuro A; Brandes AA; Rieger J; Wick A; Sepulveda J; Phuphanich S; de Souza P; Ahluwalia MS; Lim M; Vlahovic G; Sampson J, 2017, 'OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143', Neuro-Oncology, 19, pp. iii21 - iii21, http://dx.doi.org/10.1093/neuonc/nox036.071
    Journal articles | 2016
    Caixeiro NJ; Byun HL; Descallar J; Levesque JV; De Souza P; Soon Lee C, 2016, 'Health professionals' opinions on supporting a cancer biobank: Identification of barriers to combat biobanking pitfalls', European Journal of Human Genetics, 24, pp. 626 - 632, http://dx.doi.org/10.1038/ejhg.2015.191
    Journal articles | 2016
    De Souza P; Aslan P; Clark W; Patel M; Vass J; Cade D; De Silva S, 2016, 'RESIRT: A phase 1 study of Selective Internal Radiation Therapy (SIRT) using Yttrium-90 (Y-90) resin microspheres in patients with primary Renal Cell Carcinoma (RCC)', European Urology Supplements, 15, pp. e1541 - e1542, http://dx.doi.org/10.1016/s1569-9056(16)30374-8
    Journal articles | 2016
    Ho V; Chung L; Revoltar M; Lim SH; Tut TG; Abubakar A; Henderson CJ; Chua W; Ng W; Lee M; De Souza P; Morgan M; Lee CS; Shin JS, 2016, 'MRE11 and ATM expression levels predict rectal cancer survival and their association with radiotherapy response', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0167675
    Journal articles | 2016
    Lee CK; Davies L; Gebski VJ; Lord SJ; Di Leo A; Johnston S; Geyer C; Cameron D; Press MF; Ellis C; Loi S; Marschner I; Simes J; De Souza P, 2016, 'Serum human epidermal growth factor 2 extracellular domain as a predictive biomarker for lapatinib treatment efficacy in patients with advanced breast cancer', Journal of Clinical Oncology, 34, pp. 936 - 944, http://dx.doi.org/10.1200/JCO.2015.62.4767
    Journal articles | 2016
    Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, 17, http://dx.doi.org/10.3390/ijms17081264
    Journal articles | 2016
    Powles TB; Escudier B; de Souza P; Chowdhury S; Pook D; Harmenberg U; Basappa N; Geynisman D; Merchan J; Redman BG; Ryan C; Goodman O; Ho T; Singh P; Lougheed J; Patel M; Knox JJ; Motzer RJ; Choueiri TK, 2016, 'Efficacy of cabozantinib (cabo) vs everolimus (eve) by metastatic site and tumor burden in patients (pts) with advanced renal cell carcinoma (RCC) in the phase 3 METEOR trial', Annals of Oncology, 27, pp. vi284, http://dx.doi.org/10.1093/annonc/mdw373.41
    Journal articles | 2016
    Toh JWT; de Souza P; Lim SH; Singh P; Chua W; Ng W; Spring KJ, 2016, 'The Potential Value of Immunotherapy in Colorectal Cancers: Review of the Evidence for Programmed Death-1 Inhibitor Therapy', Clinical Colorectal Cancer, 15, pp. 285 - 291, http://dx.doi.org/10.1016/j.clcc.2016.07.007
    Journal articles | 2016
    Wang H; Markman B; de Souza P; Dees EC; Gangadhar TC; Piha-Paul SA; Zamboni WC; Murphy C; Senderowicz A, 2016, 'A dose-escalation study of weekly intravenous CRLX301 in patients with advanced solid tumor malignancies', ANNALS OF ONCOLOGY, 27, http://dx.doi.org/10.1093/annonc/mdw368.56
    Journal articles | 2016
    de Souza P; Aslan P; Clark W; Patel M; Vass JA; Cade D; de Silva SJ, 2016, 'Phase 1 study of selective internal radiation therapy (SIRT) with yttrium-90 (Y-90) resin microspheres in patients (pts) with renal cell carcinoma (RCC): RESIRT', ANNALS OF ONCOLOGY, 27, http://dx.doi.org/10.1093/annonc/mdw373.31
    Journal articles | 2016
    de Souza P; Chua W; Clarke S; Goldstein D; Lee C, 2016, 'Inflammatory Markers Have a Role in Renal Cell Carcinoma Prognosis', European Urology Focus, 2, pp. 341 - 342, http://dx.doi.org/10.1016/j.euf.2016.04.007
    Journal articles | 2015
    Choueiri TK; Figueroa DJ; Fay AP; Signoretti S; Liu Y; Gagnon R; Deen K; Carpenter C; Benson P; Ho TH; Pandite L; De Souza P; Powles T; Motzer RJ, 2015, 'Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: Results from COMPARZ, a randomized controlled trial', Clinical Cancer Research, 21, pp. 1071 - 1077, http://dx.doi.org/10.1158/1078-0432.CCR-14-1993
    Journal articles | 2015
    De Souza PL; Lee CS, 2015, 'The Centre for Oncology Education and Research Translation (CONCERT) Biobank', Open Journal of Bioresources, 2, http://dx.doi.org/10.5334/ojb.ai
    Journal articles | 2015
    Hnit SST; Xie C; Yao M; Holst J; Bensoussan A; De Souza P; Li Z; Dong Q, 2015, 'P27Kip1 signaling: Transcriptional and post-translational regulation', International Journal of Biochemistry and Cell Biology, 68, pp. 9 - 14, http://dx.doi.org/10.1016/j.biocel.2015.08.005
    Journal articles | 2015
    Lickliter JD; Panizza B; Karapetis CS; Gordon VA; Reddell PW; Lingard KT; Cusack RM; De Souza P, 2015, 'Phase 1 dose-escalation study of EBC-46 given by intratumoral injection to patients with refractory cutaneous and subcutaneous tumors.', Journal of Clinical Oncology, 33, pp. TPS2616 - TPS2616, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.tps2616
    Journal articles | 2015
    Lim SH; Chua W; Henderson C; Ng W; Shin JS; Chantrill L; Asghari R; Lee CS; Spring KJ; de Souza P, 2015, 'Predictive and prognostic biomarkers for neoadjuvant chemoradiotherapy in locally advanced rectal cancer', Critical Reviews in Oncology/Hematology, 96, pp. 67 - 80, http://dx.doi.org/10.1016/j.critrevonc.2015.05.003
    Journal articles | 2015
    Lim SH; Spring KJ; De Souza P; Mackenzie S; Bokey L, 2015, 'Circulating tumour cells and circulating nucleic acids as a measure of tumour dissemination in non-metastatic colorectal cancer surgery', European Journal of Surgical Oncology, 41, pp. 309 - 314, http://dx.doi.org/10.1016/j.ejso.2014.12.005
    Journal articles | 2015
    Morris MJ; Molina A; Small EJ; De Bono JS; Logothetis CJ; Fizazi K; De Souza P; Kantoff PW; Higano CS; Li J; Kheoh T; Larson SM; Matheny SL; Naini V; Burzykowski T; Griffin TW; Scher HI; Ryan CJ, 2015, 'Radiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results', Journal of Clinical Oncology, 33, pp. 1356 - 1363, http://dx.doi.org/10.1200/JCO.2014.55.3875
    Journal articles | 2015
    Mulders PFA; Smith MR; Fizazi K; Saad F; Sternberg CN; Miller K; Logothetis CJ; Shore ND; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Souza P; De Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE; Ryan CJ, 2015, '556 Abiraterone acetate improves overall survival in chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC): Impact of crossover and baseline prognostic factors in the COU-AA-302 final analysis', European Urology Supplements, 14, pp. e556 - e556a, http://dx.doi.org/10.1016/s1569-9056(15)60549-8
    Journal articles | 2015
    Nayak L; Brandes A; Omuro A; Rieger J; Wick A; Phuphanich S; Sumrall A; Sahebjam S; Ahluwalia M; de Souza P; Sepulveda JM; Maio M; Grauer O; Vlahovic G; Baehring J; Dastani H; Latek R; Coric V; Reardon D, 2015, 'QOL-07DESCRIPTION OF CLINICAL AND PATIENT REPORTED OUTCOMES ASSESSMENTS FROM A PHASE 3, MULTICENTER, RANDOMIZED TRIAL EVALUATING NIVOLUMAB MONOTHERAPY VERSUS BEVACIZUMAB IN RECURRENT GLIOBLASTOMA: CHECKMATE-143', Neuro-Oncology, 17, pp. v189.2 - v189, http://dx.doi.org/10.1093/neuonc/nov230.07
    Journal articles | 2015
    Ryan CJ; Smith MR; Fizazi K; Saad F; Mulders PFA; Sternberg CN; Miller K; Logothetis CJ; Shore ND; Small EJ; Carles J; Flaig TW; Taplin ME; Higano CS; de Souza P; de Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE, 2015, 'Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): Final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study', The Lancet Oncology, 16, pp. 152 - 160, http://dx.doi.org/10.1016/S1470-2045(14)71205-7
    Journal articles | 2015
    Saad F; Shore N; Van Poppel H; Rathkopf DE; Smith MR; De Bono JS; Logothetis CJ; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin TA; De Porre P; Londhe A; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2015, 'Impact of bone-targeted therapies in chemotherapy-naïve metastatic castration-resistant prostate cancer patients treated with abiraterone acetate: Post hoc analysis of study COU-AA-302', European Urology, 68, pp. 570 - 577, http://dx.doi.org/10.1016/j.eururo.2015.04.032
    Journal articles | 2015
    Scarano W; De Souza P; Stenzel MH, 2015, 'Dual-drug delivery of curcumin and platinum drugs in polymeric micelles enhances the synergistic effects: A double act for the treatment of multidrug-resistant cancer', Biomaterials Science, 3, pp. 163 - 174, http://dx.doi.org/10.1039/c4bm00272e
    Journal articles | 2015
    Sengupta S; Grimison P; Hayne D; Williams S; Chambers S; Desouza P; Stockler M; McJannett M; Toner G; Davis ID, 2015, 'The Australian and New Zealand Urogenital and Prostate (ANZUP) Cancer Trials Group - A new co-operative cancer trials group in genitourinary oncology', BJU International, 115, pp. 856 - 858, http://dx.doi.org/10.1111/bju.12925
    Journal articles | 2015
    Tognela A; Spring KJ; Becker T; Caixeiro NJ; Bray VJ; Yip PY; Chua W; Lim SH; de Souza P, 2015, 'Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective', Critical Reviews in Oncology/Hematology, 93, pp. 90 - 102, http://dx.doi.org/10.1016/j.critrevonc.2014.10.001
    Journal articles | 2015
    Tut TG; Lim S; Dissanayake I; Descallar J; Chua W; Ng W; De Souza P; Bokey L; Shin J-S; Soon Lee C, 2015, '14. Upregulated PLK1 expression confers radiation resistance and poor patient survival outcomes in rectal cancer', Pathology, 47, pp. S104 - S105, http://dx.doi.org/10.1097/01.pat.0000461623.74546.8a
    Journal articles | 2015
    Tut TG; Lim SHS; Dissanayake IU; Descallar J; Chua W; Ng W; De Souza P; Shin JS; Lee CS, 2015, 'Upregulated polo-like kinase 1 expression correlates with inferior survival outcomes in rectal cancer', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0129313
    Journal articles | 2014
    Becker TM; Caixeiro NJ; Lim SH; Tognela A; Kienzle N; Scott KF; Spring KJ; De Souza P, 2014, 'New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use', International Journal of Cancer, 134, pp. 2523 - 2533, http://dx.doi.org/10.1002/ijc.28516
    Journal articles | 2014
    Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; De Souza P; Becker TM, 2014, 'Circulating tumour cells - A bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, 33, pp. 747 - 756, http://dx.doi.org/10.1007/s10555-014-9502-8
    Journal articles | 2014
    Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; de Souza P; Becker TM, 2014, 'Circulating tumour cells-a bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-014-9502-8
    Journal articles | 2014
    Callari M; Aldrich-Wright JR; De Souza PL; Stenzel MH, 2014, 'Polymers with platinum drugs and other macromolecular metal complexes for cancer treatment', Progress in Polymer Science, 39, pp. 1614 - 1643, http://dx.doi.org/10.1016/j.progpolymsci.2014.05.002
    Journal articles | 2014
    Choueiri TK; Figueroa DJ; Liu Y; Gagnon RC; Deen KC; Carpenter C; Bartlett-Pandite AN; De Souza P; Powles T; Motzer RJ, 2014, 'Correlation of PDL1 tumor expression and treatment outcomes in patients with renal cell carcinoma (RCC) receiving tyrosine kinase inhibitors: COMPARZ study analysis.', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.4_suppl.416
    Journal articles | 2014
    Ho TH; Choueiri TK; D'Amelio A; Hsieh J; De Souza PL; Deen KC; Langmuir PB; Liu Y; Motzer RJ, 2014, 'The effect of SETD2 mutation (mts) on histone 3 lysine 36 trimethylation (H3K36me3) and correlation with clinical outcome in patients (pts) with metastatic clear cell renal cell carcinoma (ccRCC) enrolled in COMPARZ', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.4583
    Journal articles | 2014
    Hovey E; De Souza P; Marx G; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft P; Abdi E; Lloyd A, 2014, 'Phase III, randomized, double-blind, placebo-controlled study of modafinil for fatigue in patients treated with docetaxel-based chemotherapy', Supportive Care in Cancer, 22, pp. 1233 - 1242, http://dx.doi.org/10.1007/s00520-013-2076-0
    Journal articles | 2014
    Lee C; Davies L; Marschner I; Gebski V; Lord S; Di Leo A; Johnston SRD; Geyer CE; Cameron DA; Press MF; Ellis CE; Loi S; Simes J; De Souza P, 2014, 'Prognostic, predictive, and surrogate value of HER2 extracellular domain (ECD) for progression-free survival (PFS) in advanced breast cancer treated with lapatinib (lap): A meta-analysis.', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.630
    Journal articles | 2014
    Lim SH; Becker TM; Chua W; Caixeiro NJ; Ng WL; Kienzle N; Tognela A; Lumba S; Rasko JEJ; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer', Cancer Letters, 346, pp. 24 - 33, http://dx.doi.org/10.1016/j.canlet.2013.12.019
    Journal articles | 2014
    Lim SH; Delaney GP; Descallar J; Sayaloune P; Papadatos G; de Souza P, 2014, 'Outcomes of ethnic minority groups with node-positive, non-metastatic breast cancer in two tertiary referral centers in Sydney, Australia.', PLoS One, 9, pp. e95852, http://dx.doi.org/10.1371/journal.pone.0095852
    Journal articles | 2014
    Lim SHS; Ardern-Holmes S; McCowage G; De Souza P, 2014, 'Systemic therapy in neurofibromatosis type 2', Cancer Treatment Reviews, 40, pp. 857 - 861, http://dx.doi.org/10.1016/j.ctrv.2014.05.004
    Journal articles | 2014
    Lim SHS; Becker TM; Chua W; Ng WL; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer', Journal of Clinical Pathology, 67, pp. 848 - 853, http://dx.doi.org/10.1136/jclinpath-2014-202499
    Journal articles | 2014
    Lim SHS; Chua W; Cheng C; Descallar J; Ng W; Solomon M; Bokey L; Wong K; Lee MT; De Souza P; Shin JS; Lee CS, 2014, 'Effect of neoadjuvant chemoradiation on tumor-infiltrating/associated lymphocytes in locally advanced rectal cancers', Anticancer Research, 34, pp. 6505 - 6513
    Journal articles | 2014
    Mak G; Chin M; Nahar N; De Souza P, 2014, 'Cutaneous metastasis of prostate carcinoma treated with radiotherapy: A case presentation', BMC Research Notes, 7, http://dx.doi.org/10.1186/1756-0500-7-505
    Journal articles | 2014
    Rathkopf DE; Smith MR; De Bono JS; Logothetis CJ; Shore ND; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Van Poppel H; Carles J; Flaig TW; Efstathiou E; Yu EY; Higano CS; Taplin ME; Griffin TW; Todd MB; Yu MK; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ; Saad F, 2014, 'Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302)', European Urology, 66, pp. 815 - 825, http://dx.doi.org/10.1016/j.eururo.2014.02.056
    Journal articles | 2014
    Sebaratnam DF; Martin LK; Venugopal SS; Mangos G; Freiman J; de Souza P; Farnsworth A; Cheung K; Scolyer RA; Murrell DF, 2014, 'Diffuse melanosis cutis in the setting of BRAFV600E metastatic melanoma', International Journal of Dermatology, 53, pp. 1409 - 1411, http://dx.doi.org/10.1111/ijd.12614
    Journal articles | 2014
    Shore N; Rathkopf D; Smith MR; de Bono JS; Logothetis C; de Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2014, 'PD27-01 EFFICACY AND LONG-TERM SAFETY ANALYSIS OF STUDY COU-AA-302: ABIRATERONE ACETATE PLUS PREDNISONE IN CHEMOTHERAPY-NAÏVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER', Journal of Urology, 191, http://dx.doi.org/10.1016/j.juro.2014.02.2100
    Journal articles | 2014
    Tse BWC; Jovanovic L; Nelson CC; De Souza P; Power CA; Russell PJ, 2014, 'From Bench to Bedside: Immunotherapy for Prostate Cancer', BioMed Research International, 2014, http://dx.doi.org/10.1155/2014/981434
    Journal articles | 2014
    de Souza P, 2014, 'Convenor's Welcome', Asia-Pacific Journal of Clinical Oncology, 10, pp. 1 - 2, http://dx.doi.org/10.1111/ajco.12232
    Journal articles | 2013
    De Souza P; Begbie S; Hovey L; Rashid P; Aslan P; Malouf D; Awad N; Clements A; Hadley A; Galettis P; O'malley L; Melbourne W; Johnson L; Tran K; Lynch W, 2013, 'Phase II Trial of Intravesical Gemcitabine and Biomarker Evaluation in Patients with Superficial Urothelial Carcinoma of the Bladder', World Journal of Cancer Research, 1, pp. 131 - 137, http://dx.doi.org/10.1166/wjcr.2013.1014
    Journal articles | 2013
    Fox P; Hudson M; Brown C; Lord S; Gebski V; De Souza P; Lee CK, 2013, 'Markers of systemic inflammation predict survival in patients with advanced renal cell cancer', British Journal of Cancer, 109, pp. 147 - 153, http://dx.doi.org/10.1038/bjc.2013.300
    Journal articles | 2013
    Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Bucci J; De Souza P; Mallesara G; Murrell DF, 2013, 'Use of cetuximab as an adjuvant agent to radiotherapy and surgery in recessive dystrophic epidermolysis bullosa with squamous cell carcinoma', British Journal of Dermatology, 169, pp. 208 - 210, http://dx.doi.org/10.1111/bjd.12272
    Journal articles | 2013
    Lim S; de Souza P, 2013, 'Imatinib in neurofibromatosis type 2', BMJ case reports, 2013, http://dx.doi.org/10.1136/bcr-2013-010274
    Journal articles | 2013
    Lim S; de Souza P, 2013, 'Imatinib in neurofibromatosis type 2.', BMJ case reports, 2013
    Journal articles | 2013
    Motzer RJ; Hutson TE; Cella D; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; Souza P; Merchan JR; Boleti E; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Sternberg CN; Deen K; McCann L; Hackshaw MD; Crescenzo R; Pandite LN; Choueiri TK, 2013, 'Pazopanib versus sunitinib in metastatic renal-cell carcinoma', New England Journal of Medicine, 369, pp. 722 - 731, http://dx.doi.org/10.1056/NEJMoa1303989
    Journal articles | 2013
    Paz-Ares L; Bálint B; De Boer RH; Van Meerbeeck JP; Wierzbicki R; De Souza P; Galimi F; Haddad V; Sabin T; Hei YJ; Pan Y; Cottrell S; Hsu CP; Ramlau R, 2013, 'A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer', Journal of Thoracic Oncology, 8, pp. 329 - 337, http://dx.doi.org/10.1097/JTO.0b013e31827ce554
    Journal articles | 2013
    Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore N; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302).', Journal of Clinical Oncology, 31, pp. 5009 - 5009, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5009
    Journal articles | 2013
    Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore ND; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy.', Journal of Clinical Oncology, 31, pp. 5 - 5, http://dx.doi.org/10.1200/jco.2013.31.6_suppl.5
    Journal articles | 2013
    Ryan C; Smith M; de Bono J; Molina A; Logothetis D; De Souza P; et A, 2013, 'Abiraterone in metastatic prostate cancer without previous chemotherapy', New England Journal of Medicine, 368, pp. 138 - 148, http://dx.doi.org/10.1056/NEJMoa1209096
    Journal articles | 2013
    Saad F; Shore ND; Van Poppel H; Rathkopf D; Smith MR; de Bono JS; Logothetis C; de Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '713 ABIRATERONE ACETATE IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS WITHOUT PRIOR CHEMOTHERAPY - INTERIM ANALYSIS OF THE COU-AA-302 PHASE 3 TRIAL', Journal of Urology, 189, http://dx.doi.org/10.1016/j.juro.2013.02.272
    Journal articles | 2013
    Scarano W; Duong HTT; Lu HX; De Souza PL; Stenzel MH, 2013, 'Folate Conjugation to Polymeric Micelles via Boronic Acid Ester to Deliver Platinum Drugs to Ovarian Cancer Cell Lines', Biomacromolecules, 14, pp. 962 - 975, http://dx.doi.org/10.1021/bm400121q
    Journal articles | 2013
    Suttle A; De Souza P; Arumugham T, 2013, 'Bayesian methods for pharmacokinetic/pharmacodynamic modeling of pazopanib-induced increases in blood pressure and transaminases', Journal of Clinical Pharmacology, 53, pp. 377 - 384, http://dx.doi.org/10.1002/jcph.16
    Journal articles | 2013
    Van Poppel H; Rathkopf D; Smith MR; De Bono JS; Logothetis CJ; Shore ND; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '97 Updated interim analysis (IA): Results of randomized phase 3 study COU-AA-302 of abiraterone acetate (AA) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) without prior chemotherapy', European Urology Supplements, 12, pp. e97 - e98, http://dx.doi.org/10.1016/s1569-9056(13)60589-8
    Journal articles | 2013
    Weber MF; Smith DP; O'Connell DL; Patel MI; de Souza PL; Sitas F; Banks E, 2013, 'Risk factors for erectile dysfunction in a cohort of 108 477. Australian men', Medical Journal of Australia, 199, pp. 107 - 111, http://dx.doi.org/10.5694/mja12.11548
    Journal articles | 2013
    Won ACM; Gurney H; Marx G; De Souza P; Patel MI, 2013, 'Primary treatment of the prostate improves local palliation in men who ultimately develop castrate-resistant prostate cancer', BJU INTERNATIONAL, 112, pp. E250 - E255, http://dx.doi.org/10.1111/bju.12169
    Journal articles | 2013
    Won ACM; Gurney H; Marx G; De Souza P; Patel MI, 2013, 'Primary treatment of the prostate improves local palliation in men who ultimately develop castrate-resistant prostate cancer', BJU International, 112, http://dx.doi.org/10.1111/bju.12169
    Journal articles | 2013
    Yee GPC; De Souza P; Khachigian LM, 2013, 'Current and potential treatments for cervical cancer', Current Cancer Drug Targets, 13, pp. 205 - 220, http://dx.doi.org/10.2174/1568009611313020009
    Journal articles | 2013
    Yee GPC; De Souza PL; Khachigian LM, 2013, 'Reducing invasion potential of cervical cancer cells via targeted knockdown of c-Jun.', Journal of Clinical Oncology, 31, pp. e22005 - e22005, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e22005
    Journal articles | 2012
    Boyer M; Horwood K; Pavlakis N; De Souza P; Millward MJ; Stein B; Johnston M; Abell F; Rischin D, 2012, 'Efficacy of erlotinib in patients with advanced Non-small-cell Lung Cancer (NSCLC): Analysis of the Australian subpopulation of the TRUST study.', Asia-Pacific Journal of Clinical Oncology, 8, pp. 248 - 254, http://dx.doi.org/10.1111/j.1743-7563.2012.01540.x
    Journal articles | 2012
    Cameron BA; Bennett B; Li H; Boyle F; deSouza P; Wilcken N; Friedlander M; Goldstein D; Lloyd AR, 2012, 'Post-cancer fatigue is not associated with immune activation or altered cytokine production', Annals of Oncology, 23, pp. 2890 - 2895, http://dx.doi.org/10.1093/annonc/mds108
    Journal articles | 2012
    Coupe N; Harrison M; Chua W; De Souza P, 2012, 'Biomarkers for tyrosine kinase inhibitors in renal cell cancer', Translational Andrology and Urology, 1, pp. 216 - 222, http://dx.doi.org/10.3978/j.issn.2223-4683.2012.10.01
    Journal articles | 2012
    Goldstein D; Bennett BK; Webber K; Boyle F; De Souza P; Wilcken NRC; Scott E; Toppler R; Murie P; O''Malley L; Mccourt J; Friedlander M; Hickie IB; Lloyd AR, 2012, 'Cancer-related fatigue in women with breast cancer: outcomes of a 5 year prospective cohort study.', Journal of Clinical Oncology, 30, pp. 1805 - 1812, http://dx.doi.org/10.1200/JCO.2011.34.6148
    Journal articles | 2012
    Hovey E; de Souza P; Marx G; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Kraft P; Lloyd A, 2012, 'PHASE III, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF MODAFINIL FOR FATIGUE IN PATIENTS TREATED WITH DOCETAXEL-BASED CHEMOTHERAPY', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 44 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial', JOURNAL OF CLINICAL ONCOLOGY, 30, http://dx.doi.org/10.1200/jco.2012.30.5_suppl.211
    Journal articles | 2012
    Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', J Clin Oncol, 30, pp. 211, http://www.ncbi.nlm.nih.gov/pubmed/27967925
    Journal articles | 2012
    Hovey EJ; De Souza PL; Marx GM; Rapke T; Parente P; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', Journal of Clinical Oncology, 30, pp. e15152 - e15152, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15152
    Journal articles | 2012
    Huynh VT; Binauld SDM; De souza P; Stenzel MH, 2012, 'Acid Degradable Cross-Linked Micelles for the Delivery of Cisplatin: A Comparison with Nondegradable Cross-Linker', Chemistry of materials, 24, pp. 3197 - 3211, http://dx.doi.org/10.1021/cm301556b
    Journal articles | 2012
    Huynh VT; Quek JY; De Souza P; Stenzel MH, 2012, 'Block copolymer micelles with pendant bifunctional chelator for platinum drugs: Effect of spacer length on the viability of tumor cells', Biomacromolecules, 13, pp. 1010 - 1023, http://dx.doi.org/10.1021/bm2017299
    Journal articles | 2012
    Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Inder S; de Souza P; Mallesara G; Murrell DF, 2012, 'USE OF CETUXIMAB AS AN ADJUVANT AGENT TO RADIOTHERAPY AND SURGERY IN RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA WITH SQUAMOUS CELL CARCINOMA', WOUND REPAIR AND REGENERATION, 20, pp. A60 - A60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308945000030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Lee CK; Marschner IC; Simes RJ; Voysey M; Egleston B; Hudes G; De Souza P, 2012, 'Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus', Clinical Cancer Research, 18, pp. 3188 - 3196, http://dx.doi.org/10.1158/1078-0432.CCR-11-3137
    Journal articles | 2012
    Lemech CR; Fontela A; Arkenau H-T; Chin MTM; Li S; Liauw WS; Thomas D; De Souza PL, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours.', Journal of Clinical Oncology, 30, pp. e13585 - e13585, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e13585
    Journal articles | 2012
    Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'CORRELATION OF GRADE & HORMONE-RECEPTOR STATUS WITH STAGE IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 335 - 335, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'TUMOUR:NODE RATIO IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 37 - 37, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Lim SH; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney G, 2012, 'Outcomes of Ethnic Minority Groups With Node-Positive, Non-Metastatic Breast Cancer in a Tertiary Referral Centre in Sydney', Annals of Oncology, 23, pp. ix100 - ix100, http://dx.doi.org/10.1016/s0923-7534(20)32823-4
    Journal articles | 2012
    Motzer R; Hutson TE; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; de Souza P; Merchan JR; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Cella D; McCann L; Deen K; Choueiri TK, 2012, 'Randomized, Open-Label, Phase III Trial Of Pazopanib Versus Sunitinib In First-Line Treatment Of Patients With Metastatic Renal Cell Carcinoma (MRCC): Results of the Comparz Trial', Annals of Oncology, 23, pp. ixe13 - ixe13, http://dx.doi.org/10.1016/s0923-7534(20)34325-8
    Journal articles | 2012
    Ryan CJ; Morris M; Molina A; Piulats JR; De Souza P; Li J; Kheoh T; de Bono JS; Larson S; Griffin T; Matheny S; Naini V; Scher HI; Small E, 2012, 'Association of Radiographic Progression-Free Survival (RPFS) Adapted from Prostate Cancer Working Group 2 (PCWG2) Consensus Criteria (APCWG2) with Overall Survival (OS) in Patients (PTS) with Metastatic Castration-Resistant Prostate Cancer (MCRPC): Results from COU-AA-302', Annals of Oncology, 23, pp. ix294 - ix295, http://dx.doi.org/10.1016/s0923-7534(20)33459-1
    Journal articles | 2012
    Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; Kheoh TS; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', Journal of Clinical Oncology, 30, pp. LBA4518 - LBA4518, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.lba4518
    Journal articles | 2012
    Thientosapol E; Nelson M; Descallar J; de Souza P, 2012, 'AN EXPLORATORY ANALYSIS OF THE LONGITUDINAL RELATIONSHIPS BETWEEN PROSTATE SPECIFIC ANTIGEN AND THE INFLAMMATORY MARKERS C-REACTIVE PROTEIN AND ERYTHROCYTE SEDIMENTATION RATE', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 58 - 58, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Xu C; Xue Z; Bing NX; King K; De Souza P; et A, 2012, 'Concomitant use of pazopanib and simvastatin increases the risk of transaminase elevations in patients with cancer', Annals of Oncology, 23 Sep 2012, pp. 2470 - 2471, http://dx.doi.org/10.1093/annonc/mds249
    Journal articles | 2011
    De Souza P; Saad F, 2011, 'Bone health in prostate cancer', Expert Review of Endocrinology and Metabolism, 6, pp. 317 - 321, http://dx.doi.org/10.1586/eem.11.4
    Journal articles | 2011
    Glass SM; Huang L; King K; Ragone LJ; Ball HA; De Souza PL; Wagstaff J; Spraggs CF; Mooser VE; Pandite LN; Xu C, 2011, 'Genetic evaluation of fatigue in pazopanib-treated patients (pts) with advanced renal cell carcinoma (RCC).', J Clin Oncol, 29, pp. e15072, http://www.ncbi.nlm.nih.gov/pubmed/28020421
    Journal articles | 2011
    Gu W; Gaborieau M; Huynh VT; De Souza PL; Stenzel MH, 2011, 'Functionalization of microspheres with malonates using Michael Addition as a pathway to create a drug delivery system for platinum drugs for the treatment of liver cancer', Polymer, 52, pp. 5993 - 6002, http://dx.doi.org/10.1016/j.polymer.2011.10.054
    Journal articles | 2011
    Howes J; De Souza PL; Weston L; Huang LJ; Howes LG, 2011, 'Pharmacokinetics of phenoxodiol, a novel isoflavone, following intravenous administration to patients with advanced cancer', BMC Clinical Pharmacology, 11, pp. 1 - 8, http://dx.doi.org/10.1186/1472-6904-11-1
    Journal articles | 2011
    Huynh VT; De Souza PL; Stenzel MH, 2011, 'Polymeric micelles with pendant dicarboxylato chelating ligands prepared via a michael addition for cis -platinum drug delivery', Macromolecules, 44, pp. 7888 - 7900, http://dx.doi.org/10.1021/ma2016503
    Journal articles | 2011
    Li S; de Souza P, 2011, 'Ras isoprenylation and pAkt inhibition by zoledronic acid and fluvastatin enhances paclitaxel activity in T24 bladder cancer cells', Cancers, 3, pp. 662 - 674, http://dx.doi.org/10.3390/cancers3010662
    Journal articles | 2011
    Manners S; Galettis P; De Souza PL, 2011, 'Conditions causing gemcitabine crystallization', Journal of Oncology Pharmacy Practice, 17, pp. 395 - 399, http://dx.doi.org/10.1177/1078155210385033
    Journal articles | 2011
    Won CM; Gurney H; Marx G; De Souza P; Patel MI, 2011, 'PRIMARY TREATMENT OF THE PROSTATE IMPROVES LOCAL PALLIATION IN MEN WHO ULTIMATELY DEVELOP CASTRATE RESISTANT PROSTATE CANCER.', JOURNAL OF ENDOUROLOGY, 25, pp. A256 - A257, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296792201146&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2011
    Xu C; Bing NX; Ball HA; Rajagopalan D; Sternberg CN; Hutson T; De Souza PL; Xue ZG; McCann L; King KS; Ragone LJ; Whittaker JC; Spraggs C; Cardon LR; Mooser VE; Pandite LN, 2011, 'Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes', Journal of Clinical Oncology, 29, pp. 2557 - 2564, http://dx.doi.org/10.1200/JCO.2010.32.9110
    Journal articles | 2010
    De Souza PL; Mellado B; Pfister C; Rosenthal M; Castellano DE; Weber D; Ferrara S; Shaik N; Tan E; Patterson SA, 2010, 'Randomized phase II trial of patupilone plus prednisone versus docetaxel plus prednisone in patients with chemotherapy-naive, metastatic, castrate-resistant prostate cancer(CRPC)', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.4553
    Journal articles | 2010
    De Souza PL; North S; Bolger GB; Spiridonidis H; Lim R; Khoo KS; Phillips J; Fujimori M, 2010, 'A phase II trial of weekly i.v. KW-2170 in advanced castrate-resistant prostate cancer', Asia-Pacific Journal of Clinical Oncology, 6, pp. 292 - 297, http://dx.doi.org/10.1111/j.1743-7563.2010.01328.x
    Journal articles | 2010
    De Souza PL; Russell PJ; Kearsley J; Howes LG, 2010, 'Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer.', Nutrition Reviews, 68, pp. 542 - 555, http://dx.doi.org/10.1111/j.1753-4887.2010.00314.x
    Journal articles | 2010
    Duong HTT; Huynh TV; De Souza PL; Stenzel M, 2010, 'Core-Crosslinked Micelles synthesized by Clicking Bifunctional Pt(IV) Anticancer Drugs to Isocyanates', Biomacromolecules, 11, pp. 2290 - 2299, http://dx.doi.org/10.1021/bm100396s
    Journal articles | 2010
    Hutson TE; Davis ID; MacHiels JP; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Urology, 184, pp. 1303, http://dx.doi.org/10.1016/j.juro.2010.06.075
    Journal articles | 2010
    Hutson TE; Davis ID; Machiels JPH; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Clinical Oncology, 28, pp. 475 - 480, http://dx.doi.org/10.1200/JCO.2008.21.6994
    Journal articles | 2010
    Khasraw M; Pavlakis N; Mccowatt S; Underhill C; Begbie S; De Souza PL; Boyce A; Parnis F; Lim V; Harvie R; Marx G, 2010, 'Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer', Annals of Oncology, 21, pp. 1302 - 1307, http://dx.doi.org/10.1093/annonc/mdp524
    Journal articles | 2010
    Scott KF; Sajinovic M; Hein J; Nixdorf S; Galettis P; Liauw WS; De Souza PL; Dong Q; Graham GG; Russell PJ, 2010, 'Emerging roles for phospholipase A2 enzymes in cancer', Biochimie, 92, pp. 601 - 610, http://dx.doi.org/10.1016/j.biochi.2010.03.019
    Journal articles | 2010
    Webber K; Goldstein D; Bennett BK; Boyle FM; De Souza PL; Wilcken N; Friedlander M; Lloyd AR, 2010, 'Influence of fatigue after breast cancer adjuvant theraphy on health care utilization and percieved needs', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.9047
    Journal articles | 2010
    Yang S; De Souza PL; Alemao E; Purvis J, 2010, 'Quality of life in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha', British Journal of Cancer, 102, pp. 1456 - 1460, http://dx.doi.org/10.1038/sj.bjc.6605647
    Journal articles | 2009
    Crombie C; Burns W; Karapetis C; Lowenthal RM; Kirsten F; Davidson J; Abell F; Reece W; Iglesias J; De Souza PL, 2009, 'Randomized phase II trial of gemcitabine and either day 1 or day 8 carboplatin for advanced non-small-cell lung cancer: Is thrombocytopenia predictable?', Asia-Pacific Journal of Clinical Oncology, 5, pp. 24 - 31, http://dx.doi.org/10.1111/j.1743-7563.2009.01193.x
    Journal articles | 2009
    Figlin R; De Souza PL; McDermott D; Dutcher J; Berkenblit A; Thiele A; Krygowski M; Strahs A; Feingold J; Boni J; Hudes G, 2009, 'Analysis of PTEN and HIF-1 alpha and Correlation With Efficacy in Patients With Advanced Renal Cell Carcinoma Treated With Temsirolimus Versus Interferon-alpha', Cancer, 115, pp. 3651 - 3660, http://dx.doi.org/10.1002/cncr.24438
    Journal articles | 2009
    McPherson RAC; Galettis PT; De Souza PL, 2009, 'Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells', British Journal of Cancer, 100, pp. 649 - 655, http://dx.doi.org/10.1038/sj.bjc.6604920
    Journal articles | 2009
    Simonetti AC; Humberto de Lima Melo J; Eleutério de Souza PR; Bruneska D; Luiz de Lima Filho J, 2009, 'Immunological's host profile for HPV and Chlamydia trachomatis, a cervical cancer cofactor', Microbes and Infection, 11, pp. 435 - 442, http://dx.doi.org/10.1016/j.micinf.2009.01.004
    Journal articles | 2008
    Amaral MB; Buchholz I; Freire-Maia B; Reher P; De Souza PEA; De Marigo HA; Martins CR; Horta MCR, 2008, 'Advanced osteosarcoma of the maxilla: A case report', Medicina Oral, Patologia Oral y Cirugia Bucal, 13
    Journal articles | 2008
    Goldstein D; Bennett B; Cameron B; Boyle F; DeSouza P; Wilcken N; Friedlander M; Scott E; Hickie I; Lloyd AAM, 2008, 'A prospective cohort study of fatigue after adjuvant therapy for breast cancer: Association with hematologic, endocrine, and immune parameters', JOURNAL OF CLINICAL ONCOLOGY, 26, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.9596
    Journal articles | 2008
    Hutson TE; Davis ID; Machiels JH; de Souza PL; Baker K; Bordogna W; Westlund R; Crofts T; Pandite L; Figlin RA, 2008, 'Biomarker analysis and final efficacy and safety results of a phase II renal cell carcinoma trial with pazopanib (GW786034), a multi-kinase angiogenesis inhibitor', JOURNAL OF CLINICAL ONCOLOGY, 26, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.5046
    Journal articles | 2008
    de Souza PL; Radulovic S; Beck J; Pendergrass K; Siddique N; Dutcher JP; Berkenblit A; Thiele A; Krygowski M; Hudes GR, 2008, 'Characterization of hyperglycemia, hypercholesterolemia, and hyperlipidemia in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-α', Journal of Clinical Oncology, 26, pp. 5116 - 5116, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.5116
    Journal articles | 2007
    Friedlander ML; Buck MD; Wyld D; Findlay M; Fitzharris B; De Souza PL; Davies TM; Kalimi G; Allan S; Perez DM; Harnett PH, 2007, 'Phase II study of carboplatin followed by sequential gemcitabine and paclitaxel as first-line treatment for advanced ovarian cancer', International Journal of Gynecological Cancer, 17, pp. 350 - 358, http://dx.doi.org/10.1111/j.1525-1438.2007.00795.x
    Journal articles | 2007
    Grimison PS; Galettis P; Metharom E; De Souza PL; Links MJ; Liauw WS; Manners S; Jelinek M, 2007, 'Randomized crossover study evaluating the effect of gemcitabine infusion dose rate : evidence of auto-induction of gemcitabine accumulation', Journal of Clinical Oncology, 25, pp. 5704 - 5709, http://dx.doi.org/10.1200/JCO.2007.10.7078
    Journal articles | 2007
    Harnett PH; Buck MD; Beale P; Goldrick AJ; Allan S; Fitzharris B; De Souza PL; Links MR; Kalimi G; Davies TM; Stuart-Harris R, 2007, 'Phase II study of gemcitabine and oxaliplatin in patients with recurrent ovarian cancer: an Australian and New Zealand Gynaecological Oncology Group study', International Journal of Gynecological Cancer, 17, pp. 359 - 366, http://dx.doi.org/10.1111/j.1525-1438.2007.00763.x
    Journal articles | 2007
    Hutson TE; Davis ID; Machiels JP; de Souza PL; Hong BF; Rottey S; Baker KL; Crofts T; Pandite L; Figlin R, 2007, 'Pazopanib (GW786034) is active in metastatic renal cell carcinoma (RCC): Interim results of a phase II randomized discontinuation trial (RDT)', Journal of Clinical Oncology, 25, pp. 5031 - 5031, http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5031
    Journal articles | 2007
    de Souza P; Maart K; Laurell A; Hawkins RE; Berkenblit A; Galand L; Thiele A; Strahs A; Feingold J; Hudes G, 2007, '4011 POSTER Results of a phase 3, randomized study of patients with advanced renal cell carcinoma (RCC) and poor prognostic features treated with temsirolimus, interferon-a or the combination of temsirolimus + interferon-a', European Journal of Cancer Supplements, 5, pp. 282 - 283, http://dx.doi.org/10.1016/s1359-6349(07)71079-0
    Journal articles | 2006
    De Souza PL; Liauw WS; Links MJ; Pirabhahar S; Kelly G; Lowes LG, 2006, 'Phase I and pharmacokinetic study of weekly NV06 (Phenoxodioltrade mark), a novel isoflav-3-ene, in patients with advanced cancer', Cancer Chemotherapy and Pharmacology, 58, pp. 427 - 433, http://dx.doi.org/10.1007/s00280-006-0189-6
    Journal articles | 2006
    Gan HK; Mitchell P; Galettis P; Davis I; Cebon J; De Souza PL; Links MJ, 2006, 'A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors', Cancer Chemotherapy and Pharmacology, 58, pp. 157 - 164, http://dx.doi.org/10.1007/s00280-005-0152-y
    Journal articles | 2006
    Graham PH; Clark C; Abell F; Browne L; Capp A; Clingan PR; De Souza PL; Fox C; Links MJ, 2006, 'Concurrent-phase boost high-dose radiation therapy for non-small-cell lung cancer with or without cisplatin chemotherapy', Journal of Medical Imaging and Radiation Oncology, 50, pp. 342 - 348, http://dx.doi.org/10.1111/j.1440-1673.2006.01597.x
    Journal articles | 2004
    Rosen L; Gordon D; Tchekmedyian N; Yanagihara R; Hirsh V; Krzakowski M; Pawlicki M; De Souza PL; Zheng M; Urbanowitz G; Reitsma D; Seaman J, 2004, 'Long-term efficacy and safety of zoledronic acid in the treatment ofskeletal metastases in patients with nonsmall cell lung carcinoma andother solid tumors - A randomized, phase III, double-blind,placebo-controlled trial', Cancer, 100, pp. 2613 - 2621, http://dx.doi.org/10.1002/cncr.20308
    Journal articles | 2003
    Rosen LS; Gordon D; Tchekmedyian S; Yanagihara R; Hirsh V; Krzakowski M; Pawlicki M; de Souza P; Zheng M; Urbanowitz G; Reitsma D; Seaman JJ, 2003, 'Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial - The zoledronic acid lung cancer and other solid tumors study group', Journal of Clinical Oncology, 21, pp. 3150 - 3157, http://dx.doi.org/10.1200/JCO.2003.04.105
    Journal articles | 2003
    Souquet PJ; Price A; Jaworski M; Burillon JP; Aubert D; Fernandez O; Lewis C; De Souza P; Bosque L; Rodrigues Pereira J; Kolec V; Marel M; Astoul P; Jounieaux A; Riou R; Tack V; Deppermann KM; Gatzmeier U; Koschel G; Kreuser ED; Schlimok G; Von Pawel J; Isokangas OP; Mattson K; Torrecillas L; Lira Puerto V; Barroso N; Van Klaveren R; Gallardo D; Utraka B; Barnardt P; Tan EH; Sevilla Garcia I; Moreno Nogueira JA; Betticher D; Stahel R; Wernli M; Shih JF; Clark P; Harper P; Price A, 2003, 'Erratum: GLOB-1: A prospective randomised clinical phase III trial comparing vinorelbine-cisplatin with vinorelbine-ifosfamide-cisplatin in metastatic non-small-cell lung cancer patients (Annals of Oncology) (2002) vol. 13 (1853-1861))', Annals of Oncology, 14, pp. 347, http://dx.doi.org/10.1093/annonc/mdg083
    Journal articles | 2001
    Diamond TH; Winters J; Smith A; De Souza P; Kersley JH; Lynch WJ; Bryant C, 2001, 'The anti osteo porotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade - A double blind, randomized, placebo-controlled crossover study', CANCER, 92, pp. 1444 - 1450, http://dx.doi.org/10.1002/1097-0142(20010915)92:6<1444::AID-CNCR1468>3.0.CO;2-M
    Journal articles | 2001
    Diamond TH; Winters J; Smith A; De Souza P; Kersley JH; Lynch WJ; Bryant C, 2001, 'The antiosteoporotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade: A double blind, randomized, placebo-controlled crossover study', Cancer, 92, pp. 1444 - 1450, http://dx.doi.org/10.1002/1097-0142(20010915)92:6<1444::AID-CNCR1468>3.0.CO;2-M
    Journal articles | 2001
    Liauw W; Links M; Pirabhahar S; Husband A; Kelly G; De Souza PL, 2001, 'Phase I trial of weekly NV-06 (Phenoxodiol (TM)), a novel isoflavonoid, in patients with advanced cancer.', CLINICAL CANCER RESEARCH, 7, pp. 3694S - 3694S, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172121800205&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2000
    Cohen RM; Mueller SC; Haden K; De Souza PL, 2000, 'Phase I study of weekly vinorelbine in combination with weekly paclitaxel in adult patients with advanced refractory cancer', Cancer Investigation, 18, pp. 422 - 428, http://dx.doi.org/10.3109/07357900009032813
    Journal articles | 1997
    De Souza PL; Castillo M; Myers CE, 1997, 'Enhancement of paclitaxel activity against hormone-refractory prostate cancer cells in vitro and in vivo by quinacrine', British Journal of Cancer, 75, pp. 1593 - 1600, http://dx.doi.org/10.1038/bjc.1997.272
    Journal articles | 1997
    De Souza PL; Cooper MR; Imondi AR; Myers CE, 1997, '9-Aminocamptothecin: A topoisomerase I inhibitor with preclinical activity in prostate cancer', Clinical Cancer Research, 3, pp. 287 - 294
    Journal articles | 1996
    Stea S; Bachelor T; Cooper M; De Souza P; Koenig K; Bolton WK, 1996, 'Disposition and bioavailability of ceftazidime after intraperitoneal administration in patients receiving continuous ambulatory peritoneal dialysis', Journal of the American Society of Nephrology, 7, pp. 2399 - 2402
    Journal articles | 1995
    De Souza PL; Friedlander ML, 1995, 'Humoral hypercalcemia associated with adenocarcinoma of the rectum: A case report and review of the literature', American Journal of Clinical Oncology: Cancer Clinical Trials, 18, pp. 126 - 129, http://dx.doi.org/10.1097/00000421-199504000-00006
    Journal articles | 1994
    De Souza P; Friedlander M; Wilde C; Kirsten F; Ryan M, 1994, 'Hypersensitivity reactions to etoposide: A report of three cases and review of the literature', American Journal of Clinical Oncology: Cancer Clinical Trials, 17, pp. 387 - 389, http://dx.doi.org/10.1097/00000421-199410000-00005
    Journal articles | 1993
    De Souza P; Smith RD; Hall J; Gurney H; Harnett PR, 1993, 'A cost-utility approach to the use of 5-fluorouracil and levamisole as adjuvant chemotherapy for Dukes' C colonic carcinoma [5]', Medical Journal of Australia, 158, pp. 866, http://dx.doi.org/10.5694/j.1326-5377.1993.tb137685.x
    Journal articles | 1992
    De Souza PL; Friedlander ML, 1992, 'Prognostic factors in ovarian cancer', Hematology/Oncology Clinics of North America, 6, pp. 761 - 781, http://dx.doi.org/10.1016/s0889-8588(18)30309-5
    Journal articles | 1992
    Friedlander M; De Souza P; Segelov E, 1992, 'Risk factors, epidemiology, screening, and prognostic factors in female genital cancer', Current Opinion in Oncology, 4, pp. 913 - 922, http://dx.doi.org/10.1097/00001622-199210000-00016
  • Preprints | 2023
    Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; De Souza P; Spring KJ, 2023, Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and are Predictive of Response in Locally Advanced Rectal Cancer, , http://dx.doi.org/10.20944/preprints202306.1821.v1
    Conference Abstracts | 2022
    Gu S; de Souza PL; Shi Y; Han W; Luo S; Chen J; Day D; Frentzas S; Park JJ; Shao G; Wu S; Fang M; Haydon AM; Sun S; Lei K; Ding L; Zuo R; Gan X; Zhao Y; Chen X, 2022, 'A phase I dose-escalation and expansion study of HBM4003, an anti-CTLA-4 heavy chain only monoclonal antibody, in patients with advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. 2641 - 2641, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.2641
    Conference Abstracts | 2022
    Lee DH; Roohullah A; Cho BC; Lee S-H; Lemech C; De Souza P; Millward M; Choi J; Park KE; Kim E; Kim NY; Shin YK; Han J-Y, 2022, 'A phase I-II multicenter, open-label, dose-escalation study to evaluate the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of ABN401 in patients with advanced solid tumors and dose-expansion in patients with non-small cell lung cancer harboring c-MET dysregulation', in ANNALS OF ONCOLOGY, ELSEVIER, ELECTR NETWORK, Vol. 33, pp. S1096 - S1096, presented at Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), ELECTR NETWORK, 09 September 2022 - 13 September 2022, http://dx.doi.org/10.1016/j.annonc.2022.07.1320
    Conference Abstracts | 2022
    Lee DH; Roohullah A; Cho BC; Lemech CR; de Souza PL; Millward M; Choi JY; Park KE; Kim NY; Kim E; Lee S; Kim Y; Shin YOUNGKEE; Han J-Y, 2022, 'A phase 1 dose-escalation study of the ABN401 (c-MET inhibitor) in patients with solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. 3105 - 3105, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.3105
    Conference Abstracts | 2022
    Vasselli JR; Frentzas S; Weickhardt AJ; de Souza PL; Tang J; Wyant T; Amit I; Ofran Y; Knickerbocker A, 2022, 'Trial in progress: A phase 1-2, first-in-human, open label, dose escalation and expansion study of AU-007, a monoclonal antibody that binds to IL-2 and inhibits IL-2Rα binding, in patients with advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. TPS2671 - TPS2671, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.tps2671
    Conference Papers | 2021
    de Souza P; Park J; Day D; Frentzas S; Haydon AM; Ji J; de Assis MM; Chen X; Gan X; Tao X; Zuo R; Ross G; Lu L, 2021, 'A phase I dose-escalation study of HBM4003: An anti-CTLA-4 heavy-chain-only mAb', in ANNALS OF ONCOLOGY, ELSEVIER, ELECTR NETWORK, pp. S855 - S855, presented at Congress of the European-Society-for-Medical-Oncology (ESMO), ELECTR NETWORK, 16 September 2021 - 21 September 2021, http://dx.doi.org/10.1016/j.annonc.2021.08.1399
    Preprints | 2020
    Wimmer M; Zauner R; Ablinger M; Piñón-Hofbauer J; Guttmann-Gruber C; Reisenberger M; Lettner T; Niklas N; Proell J; Sajinovic M; De Souza P; Hainzl S; Kocher T; Murauer EM; Bauer JW; Strunk D; Reichelt J; Mellick AS; Wally V, 2020, MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotype, , http://dx.doi.org/10.1101/2020.02.05.934109
    Conference Papers | 2019
    Kotasek D; Coward J; de Souza PL; Underhill C; Jin X; Li B; Xia Y; Prawira A, 2019, 'A phase I dose escalation and dose expansion study of the anti-programmed cell death-1 (PD-1) antibody AK105.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.e14006
    Conference Abstracts | 2019
    Powderly JD; de Souza PL; Gutierrez R; Horvath L; Seitz L; Ashok D; Park A; Walters MJ; Karakunnel JJ; Berry W; Rieger A; Garofalo A; Lai DW; Chaudhry A, 2019, 'AB928, a novel dual adenosine receptor antagonist, combined with chemotherapy or AB122 (anti-PD-1) in patients (pts) with advanced tumors: Preliminary results from ongoing phase I studies.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.2604
    Conference Papers | 2018
    Bang Y-J; De Souza P; Kim S-W; Lickliter J; Naito Y; Park K; Kumar S; Mugundu GM; Kato H, 2018, 'Abstract B183: The WEE1 inhibitor AZD1775 in combination with chemotherapy in Asian patients with advanced solid tumors: a phase Ib study', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. B183 - B183, presented at Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1535-7163.targ-17-b183
    Conference Papers | 2018
    Ding PN; Becker T; Bray VJ; Chua W; Ma YF; Luk A; Po J; Lynch D; Caixeiro N; de Souza P; Roberts TL, 2018, 'Longitudinal analysis of circulating biomarkers to monitor advanced EGFR mutated (EGFR+) non-small cell lung cancer (NSCLC)', in Annals of oncology : official journal of the European Society for Medical Oncology, OXFORD UNIV PRESS, Munich, GERMANY, pp. viii660, presented at 43rd ESMO Congress (ESMO), Munich, GERMANY, 19 October 2018 - 23 October 2018, http://dx.doi.org/10.1093/annonc/mdy303.033
    Conference Abstracts | 2018
    Rachumalla PR; Carson E; Cooper A; Wilkinson K; Asghari R; Adams D; Ng W; Chua W; Roohullah A; De Souza P, 2018, 'Retrospective analysis of clinical characteristics and outcomes for patients enrolled in oncology phase 0 and phase 1 clinical trials at Liverpool Cancer Therapy Centre', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 14, pp. 168 - 169, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200283&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2018
    Rachumalla PR; Descallar J; Pal A; Wilson BE; Xuan W; Kiely BE; Mok K; Moylan E; Balakrishnar B; Adams D; Harvey S; Harrison M; Tognela A; Asghari R; DellaFiorentina S; De Souza P; Yap M; Lim K; Delaney G; Papadatos G; Boxer M; Vinod S; Lee CI, 2018, 'Is serum CA15-3 useful for assessing disease progression during systemic therapy in patients with metastatic breast cancer (MBC)?', Vol. 14, pp. 168 - 168, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200282&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Bergin ART; Hovey E; Lloyd A; Marx G; Parente P; Rapke T; de Souza P, 2017, 'Docetaxel-related fatigue in men with metastatic prostate cancer: a descriptive analysis', in Supportive Care in Cancer, pp. 2871 - 2879, http://dx.doi.org/10.1007/s00520-017-3706-8
    Conference Abstracts | 2017
    Carson E; Cooper A; De Souza P; Chua W, 2017, 'Retrospective Analysis of Clinical Characteristics and Outcomes for Patients Enrolled on Oncology Phase I Clinical Trials at Liverpool Hospital Cancer Therapy Centre', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 13, pp. 117 - 117, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413954500150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Lim SH-S; Ip E; Chua W; Ng W; Henderson C; Shin J-S; Harris BHL; Barberis A; Cowley M; De Souza PL; Spring K, 2017, 'Serum microRNA expression during neoadjuvant chemoradiation for rectal cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.e15081
    Conference Abstracts | 2016
    Brungs D; Healey E; Rose J; Tubaro T; Ng W; Chua W; Carolan M; de Souza P; Aghmesheh M; Ranson M, 2016, 'Adjuvant chemotherapy for stage III colorectal cancer in the elderly', in Annals of Oncology, OXFORD UNIV PRESS, Copenhagen, DENMARK, Vol. 27, pp. vi182, presented at 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK, 07 October 2016 - 11 October 2016, http://dx.doi.org/10.1093/annonc/mdw370.101
    Conference Papers | 2016
    Lim SH; De Souza P; Chua W; Ng W; Harris B; Cowley MJ; Spring K, 2016, 'Change in serum microRNA expression during neoadjuvant chemoradiation for rectal cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1942
    Conference Papers | 2016
    Markman B; De Souza PL; Dees EC; Gangadhar TC; Cooper A; Roohullah A; Boolell V; Zamboni W; Murphy C; Senderowicz AM; Wang H, 2016, 'A phase 1 study of CRLX301, a novel nanoparticle-drug conjugate (NDC) containing docetaxel (DOC), in patients with refractory solid tumors.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.2526
    Conference Abstracts | 2016
    Revoltar M; Shin J-S; Lim S; Tut T-G; Dissanayake I; Descallar J; Ho V; Chua W; Ng W; Lee M; Henderson C; De Souza P; Morgan M; Lee CS, 2016, 'Early marker of DNA damage response, atm, as a predictor of clinical outcome following radiotherapy in rectal cancer patients.', in Pathology, England, Vol. 48 Suppl 1, pp. S153, England, http://dx.doi.org/10.1016/j.pathol.2015.12.417
    Conference Papers | 2016
    Zamboni WC; Markman B; de Souza P; Dees EC; Gangadhar T; Eliasof S; Murphy C; Senderowicz A; Wang H, 2016, 'Abstract 2047: Pharmacokinetics (PK) of CRLX301, a novel nanoparticle-drug conjugate (NDC) containing the payload docetaxel, in patients with refractory solid tumors', in Cancer Research, American Association for Cancer Research (AACR), pp. 2047 - 2047, presented at Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA, http://dx.doi.org/10.1158/1538-7445.am2016-2047
    Conference Abstracts | 2015
    Basch EM; Sholz MC; De Bono JS; Vogelzang NJ; De Souza PL; Marx GM; Vaishampayan UN; George S; Schwarz JK; Antonarakis ES; O'Sullivan JM; Kelabasty AR; Chi KN; Dreicer R; Hutson TE; Mangeshkar M; Holland JS; Weitzman A; Scher HI, 2015, 'Final analysis COMET-2: Cabozantinib (Cabo) versus mitoxantrone/prednisone (MP) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with moderate to severe pain who were previously treated with docetaxel(D) and abiraterone (A) and/or enzalutamide (E)', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, Vol. 33, presented at Genitourinary Cancers Symposium, FL, Orlando, 26 February 2015 - 28 February 2015, http://dx.doi.org/10.1200/jco.2015.33.7_suppl.141
    Conference Abstracts | 2015
    De Souza P; Smith MR; Fizazi K; Saad F; Mulders PFA; Sternberg CN; Miller K; Logothetis CJ; Shore N; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE; Ryan CJ, 2015, 'Final analysis of the randomised, phase 3, COU-AA-302 study of abiraterone acetate (AA) in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (mCRPC)', in BJU INTERNATIONAL, WILEY-BLACKWELL, AUSTRALIA, Adelaide, Vol. 115, pp. 21 - 22, presented at 68th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, AUSTRALIA, Adelaide, 11 April 2015 - 14 April 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351395100042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Lim S; Chua W; Ng W; Descallar J; Bokey L; Spring K; De Souza P, 2015, 'Presence of circulating tumour cells and correlation with inflammatory markers in non-metastatic rectal cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 51, pp. S391 - S391, presented at European Cancer Congress, AUSTRIA, Vienna, http://dx.doi.org/10.1016/S0959-8049(16)31092-9
    Conference Abstracts | 2015
    Lim S; Ng W; Chua W; Descallar J; Spring K; De Souza P, 2015, 'Quality of life and circulating tumour cells in patients treated with neoadjuvant chemoradiation for rectal cancer - is there a link?', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 51, pp. S224 - S224, presented at European Cancer Congress, AUSTRIA, Vienna, http://dx.doi.org/10.1016/S0959-8049(16)30648-7
    Conference Abstracts | 2015
    Lim SH; Ng W; Chua W; Descallar J; Spring K; De Souza P, 2015, 'Psychological parameters and circulating tumor cells in locally advanced rectal cancer', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 57 - 57, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000357957300039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Lim SH; Spring K; Chua W; Ng W; Descallar J; Ma Y; Becker TM; De Souza P, 2015, 'Circulating Tumor Cells in Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, TX, San Antonio, Vol. 93, pp. E522 - E523, presented at 57th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), TX, San Antonio, 18 October 2015 - 21 October 2015, http://dx.doi.org/10.1016/j.ijrobp.2015.07.1883
    Conference Presentations | 2015
    Padinharakam S; Chua W; Lim S; Karikios D; Adams D; Della-Fiorentina S; Desouza P; Moylan E; Harrison M; Descallar J; Balakrishnar B, 2015, 'Patterns of care and outcomes among sarcomatoid renal cell carcinoma patients in South Western Sydney', Vol. 11, pp. 180 - 180, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800331&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2015
    Ryan CJ; Smith MR; Fizazi K; Saad F; Sternberg CN; Logothetis C; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Souza PL; De Bono JS; Griffin TW; De Porre P; Park YC; Li J; Kheoh TS; Molina A; Rathkopf DE, 2015, 'Impact of crossover and baseline prognostic factors on overall survival (OS) with abiraterone acetate (AA) in the COU-AA-302 final analysis.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, presented at Genitourinary Cancers Symposium, FL, Orlando, 26 February 2015 - 28 February 2015, http://dx.doi.org/10.1200/jco.2015.33.7_suppl.142
    Conference Papers | 2015
    Spring K; Lim S; Descallar J; Ng W; Chua W; de Souza P; Bokey L; MacKenzie S, 2015, 'Circulating tumour cell release in the peri-operative setting during curative colorectal cancer surgery', in Annals of Oncology, Oxford University Press (OUP), Barcelona, SPAIN, presented at ESMO 17th World Congress on Gastrointestinal Cancer, Barcelona, SPAIN, 01 July 2015 - 04 July 2015, http://dx.doi.org/10.1093/annonc/mdv233.297
    Conference Papers | 2014
    Lim SH-S; Shin J-S; Tut TG; Ng WTW; Chug W; Dissanayake IU; Spring K; Ng W; Bokey L; De Souza P; Lee CS, 2014, 'Polo-like kinase 1 as a biomarker in rectal cancers', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e14542
    Conference Papers | 2014
    Lim SH; Shin J-S; Tut TG; Ng WTW; Chua W; Dissanayake IU; Spring KJ; Bokey EL; Ng W; de Souza P; Lee CS, 2014, 'POLO-LIKE KINASE 1 AS A BIOMARKER IN RECTAL CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 60 - 60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Yu EY; Saad F; Londhe A; Shore ND; Van Poppel H; Rathkopf DE; Smith MR; Logothetis C; De Souza PL; Fizazi K; Mulders PFA; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Small EJ; Scher HI; Griffin TW; Yu MK; Ryan CJ, 2014, 'Association of alkaline phosphatase (ALP) with clinical outcomes in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, presented at Genitourinary Cancers Symposium, CA, San Francisco, 30 January 2014 - 01 February 2014, http://dx.doi.org/10.1200/jco.2014.32.4_suppl.27
    Conference Papers | 2013
    Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore N; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302)', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419601610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore ND; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, presented at Genitourinary Cancers Symposium of the Conquer-Cancer-Foundation of American-Society-of-Clinical-Oncology (ASCO), FL, Orlando, 14 February 2013 - 16 February 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333679600009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Yee GPC; De Souza PL; Khachigian LM, 2013, 'Reducing invasion potential of cervical cancer cells via targeted knockdown of c-Jun', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419605150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Hovey EJ; De Souza P; Marx G; Parente P; Rapke T; et A, 2012, 'Phase III, randomised, double-blind, placebo-controlled study of Modafinil for fatigue in patients treated with Docetaxel-based chemotherapy', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia Pty Ltd, Australia, pp. 26 - 26, presented at ANZUP Annual Scientific Meeting, State of the art Multi-Disciplinary Care in Urological Cancers, Sydney Darling Harbour, 15 July 2012 - 17 July 2012, http://dx.doi.org/10.1111/j.1743-7563.2012.01574_3.x
    Conference Papers | 2012
    Hovey EJ; De Souza PL; Marx GM; Rapke T; Parente P; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318009803130&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Lemech C; Fontela A; Arkenau H; Chin M; Li S; Liauw WS; Thomas D; De Souza P, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours', in Journal of clinical oncology - official journal of the American Society of Clinical Oncology, American Society of Clinical Oncology, New York, pp. e13585 - e13585, presented at ASCO Annual Meeting, Chicago, USA, 01 June 2012 - 05 June 2012, http://meeting.ascopubs.org/gca?gca=ascomtg%3B30%2F15_suppl%2Fe13585&allch=&submit=Go#abstr-1
    Conference Papers | 2012
    Lim S; Descallar J; Sayaloune P; Delaney GP; Papadatos G; De Souza P, 2012, 'Tumour:node ratio in node-positive, non-metastatic breast cancer', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia, Australia, pp. 8 37-37; 2 SI AUG 2012, presented at ANZUP Annual Scientific Meeting
    Conference Papers | 2012
    Lim S; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney GP, 2012, 'Outcomes of ethnic minority groups with node-positive, non-metastatic breast cancer in a tertiary referral centre in Sydney', in Annals of Oncology, Oxford Univ Press, Oxford, England, pp. 23 100-100; 9 SEP 2012, presented at ESMO Congress Vienna, http://dx.doi.org/10.1371/journal.pone.0095852
    Conference Papers | 2012
    Lim SH; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney G, 2012, 'OUTCOMES OF ETHNIC MINORITY GROUPS WITH NODE-POSITIVE, NON-METASTATIC BREAST CANCER IN A TERTIARY REFERRAL CENTRE IN SYDNEY', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, AUSTRIA, Vienna, pp. 100 - 100, presented at 37th Congress of the European-Society-for-Medical-Oncology (ESMO), AUSTRIA, Vienna, 28 September 2012 - 02 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309409000256&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Melbourne W; Tran K; Johnson LA; De Souza P; Lynch W, 2012, 'hENT1 expression in human urothelium; evaluating hENT1 prognostic potential for intravesical Gemcitabine treatment outcome in patients with superficial urothelial carcinoma', in BJU International, Urological Society of Australia and New Zealand, Darwin, pp. 109 40-40; 4 SI APR 2012, presented at Urological Society of Australia and New Zealand, Darwin
    Conference Papers | 2012
    Ryan C; Morris M; Molina A; Piulats J; De Souza P; Li J; Kheoh T; de Bono J; Larson S; Griffin T; Matheny S; Naini V, 2012, 'Association of Radiographic Progression-Free Survival (Rpfs) adapted from Prostate Cancer Working Group 2 (Pcwg2) Consensus Criteria (Apcwg2) with Overall Survival (Os) in Patients (Pts) with Metastatic Castration-Resistant Prostate Cancer (Mcrpc): Results from Cou-Aa-302', in Annals of Oncology, Oxford Univ Press, Oxford, England, pp. 23 294-295; 9 SEP 2012, presented at ESMO Congress Vienna, Vienna, AUSTRIA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309409001375&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2012
    Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; Kheoh TS; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate (AA) in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 01 June 2012 - 05 June 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318026200024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; San Kheoh T; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, http://dx.doi.org/10.1200/jco.2012.30.18_suppl.lba4518
    Conference Papers | 2011
    Kim MH; Li M; Mather-hillon J; Melbourne W; Tran K; Daniels BS; De Souza PL; Mallesara G; Murrell DF, 2011, 'Increased expression of EGFR in squamous cell carcinoma in recessive dystrophic epidermolysis bullosa and response to Cetuximab', in Australasian Journal of Dermatology, New South Wales : Wiley-Blackwell, Australia, pp. 32 - 32, presented at Abstracts of the Australasian College of Dermatologists 44th Annual Scientific Meeting, Perth Western Australia, 15 May 2011 - 18 May 2011, http://dx.doi.org/10.1111/j.1440-0960.2011.00757.x
    Conference Papers | 2010
    Paz-Ares L; Balint B; de Boer R; van Meerbeeck JP; Wierzbicki R; Desouza PL; Galimi F; Haddad V; Hei Y; Ramlau R, 2010, 'A RANDOMIZED, PHASE 2 STUDY OF PACLITAXEL (P) AND CARBOPLATIN (C) +/- CONATUMUMAB (CON) FOR FIRST-LINE TREATMENT OF NON-SMALL CELL LUNG CANCER (NSCLC)', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, ITALY, Milan, pp. 137 - 137, presented at 35th European-Society-for-Medical-Oncology (ESMO) Congress, ITALY, Milan, 08 October 2010 - 12 October 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283115900427&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Webber K; Goldstein D; Bennett BK; Boyle F; De Souza PL; Wilken N; Friedlander M; Lloyd AR, 2010, 'Fatigue after adjuvant therapy for breast cancer influences health care utilisation and perceived needs', in Grunberg SM (ed.), Journal of Clinical Oncology, American Society of Clinical Oncology, Virginia USA, pp. 647s, presented at ., -
    Conference Papers | 2010
    Webber K; Goldstein D; Bennett BK; Boyle F; De Souza PL; Wilken N; Friedlander M; Lloyd AR, 2010, 'Late fatigue after adjuvant therapy for early breast cancer is largely unrelated to cancer or its treatment: 5 year follow-up of a prospective cohort study', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia Pty Ltd, Australia, pp. 53 - 60, presented at ., -
    Conference Papers | 2009
    Dutcher J; De Souza PL; McDermott D; Figlin R; Berkenblit A; Thiele A; Krygowski M; Strahs A; Feingold J; Hudes G, 2009, 'Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies', in Medical Oncology, Humana Press Inc, Totowa, NJ, USA, pp. 202 - 209, presented at Medical Oncology, http://dx.doi.org/10.1007/s12032-009-9177-0
    Conference Papers | 2009
    Metharom E; Galettis P; Manners S; Jelinek M; De Souza PL; Links MJ, 2009, 'Cytidine Deaminase c.79A > C Polymorphism Affected Optimal Dose Delivery of Gemcitabine', in Drug Metabolism Reviews, Marcel Dekker Inc, New York, NY, USA, pp. 231 - 232, presented at Drug Metabolism Reviews
    Conference Papers | 2009
    Webber K; Fontela A; Bonner N; Bell J; Bucci J; Lewis CR; De Souza PL; Graham PH; Links MJ, 2009, 'CRP predicts tolerance of treatment and overall survival with weekly carboplatin-paclitaxel and concomitant irradiation for locally advanced non-small cell lung cancer', in Journal of Thoracic Oncology, Lippincott Williams & Wilkins, USA, pp. S864 - S865, presented at 13th World Conference on Lung Cancer, San Francisco, USA, 31 July 2009 - 04 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000269496002560&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Bennett BK; Goldstein D; Friedlander ML; Boyle F; De Souza PL; Wilken N; Hickie IB; Scott E; Lloyd AR, 2008, 'A prospective cohort study of fatigue after adjuvant therapy for breast cancer', in Psycho - Oncology, John Wiley & Sons Ltd, Chichester, W Sussex, England, pp. S36 - S37, presented at Psycho-Oncology 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000257874200071&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Venugopal S; Martin L; Mangos G; Freiman J; Cheung K; Farnsworth AE; De Souza PL; Murrell DF, 2008, 'A study of rare presentations of metastatic melanoma', in Australasian Journal of Dermatology, New South Wales : Wiley-Blackwell, Australia, pp. A75 - A76, presented at Australasian Dermatopathology Society, 29th Annual Conference, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259822500004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2007
    Chin MTM; Links MJ; Szwajcer ; De Souza PL, 2007, 'Lessons learnt in evaluating the target of drug action in a phase 1 trial of oral albendazole –a benzimidazole carbamate anti-helminthic- in patients with cancer refractory to conventional treatments.', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia, Australia, pp. A79 - A79, presented at Clinical Oncological Society of Australia (COSA) Annual Scientific Meeting 2007, Adelaide, Australia, http://www3.interscience.wiley.com/cgi-bin/fulltext/118500669/PDFSTART