Professor Paul De Souza

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Research Interests:
As a translational cancer researcher I am interested in applying sound biological and pharmacological principles to overcome the 'Valley of Death' in Drug Development. I focus on translating preclinical data into early Phase clinical trials of novel treatments, and discovering novel biomarkers (especially through liquid biopsy) that may help predict response or resistance to treatment: bench to bedside, and back to bench research. Individual cancers of interest include genitourinary, especially prostate, and brain tumours.

Broad Research Areas:
Cancer, Clinical Research, Cell Biology and Gene Regulation, Lipids, Pharmacology

Qualifications:
BScMed MB BS MPH Syd, PhD UNSW, FRACP

Society Memberships & Professional Activities:
ASCO, AACR, MOG, COSA

Specific Research Keywords:
Prostate Cancer, Brain Cancer, Cancer Drug Development and Pharmacology, Renal Cancer, Bladder Cancer

Phone

+61-2-85569300

Book Chapters | 2021

Po JW; Ma Y; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'PD-L1 Detection on Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 223 - 233, http://dx.doi.org/10.1007/978-1-0716-1205-7_17

Book Chapters | 2021

Po JW; Ma Y; Luk AWS; Lynch D; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'Single-Cell Analysis of BRAF^V600E and NRAS^Q61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 277 - 286, http://dx.doi.org/10.1007/978-1-0716-1205-7_21

Book Chapters | 2016

Po JW; Lynch D; de Souza P; Becker TM, 2016, 'Importance and Detection of Epithelial-to-Mesenchymal Transition (EMT) Phenotype in CTCs', in Xu K (ed.), TUMOR METASTASIS, INTECH EUROPE, pp. 241 - 256, http://dx.doi.org/10.5772/64342

Book Chapters | 2012

A C; Scott K; Bucci J; Greenfield H; Dong Q; de Souz PL, 2012, 'Dietary Manipulation for Therapeutic Effect in Prostate Cancer', in Cancer Prevention - From Mechanisms to Translational Benefits, InTech, http://dx.doi.org/10.5772/32620
Journal articles | 2024

Redwood L; Saarinen K; Ivers R; Garne D; de Souza P; Bonney A; Rhee J; Mullan J; Thomas SJ, 2024, 'Alcohol consumption and health-related quality of life in regional, rural and metropolitan Australia: analysis of cross-sectional data from the Community Health and Rural/Regional Medicine (CHARM) study', Quality of Life Research, 33, pp. 349 - 360, http://dx.doi.org/10.1007/s11136-023-03522-x

Journal articles | 2023

Gano C; Fatima S; Failes T; Arndt G; Sajinovic M; Mahns D; Saedisomeolia A; Coorssen J; Bucci J; DeSouza P; Vafaee F; Scott K, 2023, 'Anti-cancer potential of synergistic phytochemical combinations is influenced by the genetic profiles of prostate cancer cell lines', Frontiers in Nutrition, http://dx.doi.org/10.3389/fnut.2023.1119274

Journal articles | 2023

Gao B; Voskoboynik M; Cooper A; Wilkinson K; Hoon S; Hsieh CY; Cai S; Tian YE; Bao J; Ma N; Wang C; Zhang M; Li B; Guo M; Zhou R; Wang X; Xu C; de Souza P, 2023, 'A phase 1 dose-escalation study of the poly(ADP-ribose) polymerase inhibitor senaparib in Australian patients with advanced solid tumors', Cancer, 129, pp. 1041 - 1050, http://dx.doi.org/10.1002/cncr.34662

Journal articles | 2023

Grebstad Tune B; Sareen H; Powter B; Kahana-Edwin S; Cooper A; Koh ES; Lee CS; Po JW; McCowage G; Dexter M; Cain L; O’Neill G; Prior V; Karpelowsky J; Tsoli M; Baumbusch LO; Ziegler D; Roberts TL; DeSouza P; Becker TM; Ma Y, 2023, 'From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients', Biomedicines, 11, http://dx.doi.org/10.3390/biomedicines11112907

Journal articles | 2023

Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; de Souza P; Spring KJ, 2023, 'Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and Are Predictive of Response in Locally Advanced Rectal Cancer', Cancers, 15, http://dx.doi.org/10.3390/cancers15164184

Journal articles | 2022

Fatima S; Ma Y; Safrachi A; Haider S; Spring KJ; Vafaee F; Scott KF; Roberts TL; Becker TM; de Souza P, 2022, 'Harnessing Liquid Biopsies to Guide Immune Checkpoint Inhibitor Therapy', Cancers, 14, http://dx.doi.org/10.3390/cancers14071669

Journal articles | 2022

Hnit SST; Yao M; Xie C; Bi L; Wong M; Liu T; De Souza P; Li Z; Dong Q, 2022, 'Apigenin impedes cell cycle progression at G2 phase in prostate cancer cells', Discover Oncology, 13, pp. 44, http://dx.doi.org/10.1007/s12672-022-00505-1

Journal articles | 2022

Jeffreys SA; Becker TM; Khan S; Soon P; Neubauer H; de Souza P; Powter B, 2022, 'Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis', Frontiers in Endocrinology, 13, http://dx.doi.org/10.3389/fendo.2022.895729

Journal articles | 2022

Khan T; Becker TM; Scott KF; Descallar J; de Souza P; Chua W; Ma Y, 2022, 'Prognostic and Predictive Value of Liquid Biopsy-Derived Androgen Receptor Variant 7 (AR-V7) in Prostate Cancer: A Systematic Review and Meta-Analysis', Frontiers in Oncology, 12, http://dx.doi.org/10.3389/fonc.2022.868031

Journal articles | 2022

Khan T; Lock JG; Ma Y; Harman DG; de Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, 'Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-20079-w

Journal articles | 2022

Lai HC; Ho UY; James A; De Souza P; Roberts TL, 2022, 'RNA metabolism and links to inflammatory regulation and disease', Cellular and Molecular Life Sciences, 79, http://dx.doi.org/10.1007/s00018-021-04073-5

Journal articles | 2022

Rottey S; Clarke J; Aung K; Machiels JP; Markman B; Heinhuis KM; Millward M; Lolkema M; Patel SP; De Souza P; Duca M; Curigliano G; Santoro A; Koyama T; Brown M; Vezina H; He C; Siu-Chung Chu Q, 2022, 'Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors', Clinical Cancer Research, 28, pp. 95 - 105, http://dx.doi.org/10.1158/1078-0432.CCR-21-1181

Journal articles | 2022

Sareen H; Ma Y; Becker TM; Roberts TL; de Souza P; Powter B, 2022, 'Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis', International journal of molecular sciences, 23, http://dx.doi.org/10.3390/ijms23168835

Journal articles | 2022

Young FP; Becker TM; Nimir M; Opperman T; Chua W; Balakrishnar B; de Souza P; Ma Y, 2022, 'Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11010257

Journal articles | 2022

de Souza PL; Aslan P; Clark W; Nour R; de Silva S, 2022, 'RESIRT: A Phase 1 Study of Selective Internal Radiation Therapy Using Yttrium-90 Resin Microspheres in Patients With Primary Renal Cell Carcinoma', Clinical Genitourinary Cancer, 20, pp. 442 - 451, http://dx.doi.org/10.1016/j.clgc.2022.05.006

Journal articles | 2021

Ardern-Holmes S; White C; Bahure S; So S; McCowage G; Hovey E; Troon S; De Souza P; Simes J; Slancar M; Dexter M; Wong M, 2021, 'The Effect of Bevacizumab on Vestibular Schwannoma Related to Neurofibromatosis Type 2', Australasian Journal of Neuroscience, 31, pp. 5 - 14, http://dx.doi.org/10.21307/ajon-2021-002

Journal articles | 2021

Cameron B; Webber K; Li H; Bennett BK; Boyle F; de Souza P; Wilcken N; Lynch J; Friedlander M; Goldstein D; Lloyd AR, 2021, 'Genetic associations of fatigue and other symptoms following breast cancer treatment: A prospective study', Brain, Behavior, and Immunity - Health, 10, pp. 100189, http://dx.doi.org/10.1016/j.bbih.2020.100189

Journal articles | 2021

Ding PN; Roberts TL; Chua W; Becker TM; Caixeiro N; de Souza P; Gao B; Lee CK; Itchins M; Westman H; Clarke S; Blinman P; Kao S; John T; Leal JL; Bray VJ, 2021, 'Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib', Translational Lung Cancer Research, 10, pp. 1623 - 1634, http://dx.doi.org/10.21037/tlcr-20-1125

Journal articles | 2021

Garrett C; Becker TM; Lynch D; Po J; Xuan W; Scott KF; De Souza P, 2021, 'Comparison of neutrophil to lymphocyte ratio and prognostic nutritional index with other clinical and molecular biomarkers for prediction of glioblastoma multiforme outcome', PLoS ONE, 16, http://dx.doi.org/10.1371/journal.pone.0252614

Journal articles | 2021

Hnit SST; Ding R; Bi L; Xie C; Yao M; De Souza P; Xu L; Li Z; Dong Q, 2021, 'Agrimol B present in Agrimonia pilosa Ledeb impedes cell cycle progression of cancer cells through G0 state arrest', Biomedicine and Pharmacotherapy, 141, http://dx.doi.org/10.1016/j.biopha.2021.111795

Journal articles | 2021

Lai HC; James A; Luff J; De Souza P; Quek H; Ho U; Lavin MF; Roberts TL, 2021, 'Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages', Journal of Leukocyte Biology, 109, pp. 593 - 603, http://dx.doi.org/10.1002/JLB.2AB0420-151RR

Journal articles | 2021

Lee DH; Roohullah A; Cho BC; Lemech C; de Souza P; Millward M; Choi J; Park KE; Lee M; Kim Y; Park S; Lee J; Kim J; Shin YK; Han J-Y, 2021, 'Phase I dose-escalation study to evaluate safety and clinical activity of c-MET inhibitor ABN401 in patients with advanced solid tumor', ANNALS OF ONCOLOGY, 32, pp. S1029 - S1030, http://dx.doi.org/10.1016/j.annonc.2021.08.1958

Journal articles | 2021

Lee DH; Roohullah A; Cho BC; Lemech CR; de Souza PL; Millward M; Choi JY; Park KE; Lee M; Kim Y; Shin Y; Han J-Y, 2021, 'Trial in progress: A phase 1-2 multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of ABN401 in patients with advanced solid tumors.', JOURNAL OF CLINICAL ONCOLOGY, 39, http://dx.doi.org/10.1200/JCO.2021.39.15_suppl.TPS3157

Journal articles | 2021

Nabil WNN; Xi Z; Song Z; Jin L; Zhang XD; Zhou H; De Souza P; Dong Q; Xu H, 2021, 'Towards a framework for better understanding of quiescent cancer cells', Cells, 10, pp. 1 - 19, http://dx.doi.org/10.3390/cells10030562

Journal articles | 2021

Piha-Paul SA; Thein KZ; De Souza P; Kefford R; Gangadhar T; Smith C; Schuster S; Zamboni WC; Dees CE; Markman B, 2021, 'First‐in‐human, phase I/IIa study of CRLX301, a nanoparticle drug conjugate containing docetaxel, in patients with advanced or metastatic solid malignancies', Investigational New Drugs, 39, pp. 1047 - 1056, http://dx.doi.org/10.1007/s10637-021-01081-x

Journal articles | 2021

Powter B; Jeffreys SA; Sareen H; Cooper A; Brungs D; Po J; Roberts T; Koh ES; Scott KF; Sajinovic M; Vessey JY; de Souza P; Becker TM, 2021, 'Human TERT promoter mutations as a prognostic biomarker in glioma', Journal of Cancer Research and Clinical Oncology, 147, pp. 1007 - 1017, http://dx.doi.org/10.1007/s00432-021-03536-3

Journal articles | 2021

Razdan A; Main NM; Chiu V; Shackel NA; de Souza P; Bryant K; Scott KF, 2021, 'Targeting the eicosanoid pathway in hepatocellular carcinoma', AMERICAN JOURNAL OF CANCER RESEARCH, 11, pp. 2456 - 2476, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667209700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2021

Roohullah A; Ganju V; Zhang F; Zhang L; Yu T; Wilkinson K; Cooper A; de Souza P, 2021, 'First-in-human phase 1 dose escalation study of HX009, a novel recombinant humanized anti-PD-1 and CD47 bispecific antibody, in patients with advanced malignancies.', JOURNAL OF CLINICAL ONCOLOGY, 39, http://dx.doi.org/10.1200/JCO.2021.39.15_suppl.2517

Journal articles | 2021

Scott KF; Mann TJ; Fatima S; Sajinovic M; Razdan A; Kim RR; Cooper A; Roohullah A; Bryant KJ; Gamage KK; Harman DG; Vafaee F; Graham GG; Church WB; Russell PJ; Dong Q; de Souza P, 2021, 'Human group iia phospholipase A2 —three decades on from its discovery', Molecules, 26, http://dx.doi.org/10.3390/molecules26237267

Journal articles | 2020

Ackland SP; Michael M; de Souza P; Martin JH; Clarke SJ; Francis K; Karapetis CS; Gurney H, 2020, 'Science and art of anticancer drug dosing: nine steps to personalised therapy', Internal Medicine Journal, 50, pp. 992 - 996, http://dx.doi.org/10.1111/imj.14948

Journal articles | 2020

Aghajani MJ; Yang T; Schmitz U; James A; McCafferty CE; de Souza P; Niles N; Roberts TL, 2020, 'Epithelial-to-mesenchymal transition and its association with PD-L1 and CD8 in thyroid cancer', Endocrine Connections, 9, pp. 1028 - 1041, http://dx.doi.org/10.1530/EC-20-0268

Journal articles | 2020

Bi L; Xie C; Jiao L; Jin S; Hnit SST; Mu Y; Wang Y; Wang Q; Ge G; Wang Y; Zhao X; Shi X; Kang Y; De Souza P; Liu T; Zhou J; Xu L; Dong Q, 2020, 'CPF impedes cell cycle re-entry of quiescent lung cancer cells through transcriptional suppression of FACT and c-MYC', Journal of Cellular and Molecular Medicine, 24, pp. 2229 - 2239, http://dx.doi.org/10.1111/jcmm.14897

Journal articles | 2020

Broom A; Parker R; Raymond S; Kirby E; Lewis S; Kokanović R; Adams J; de Souza P; Woodland L; Wyld D; Lwin Z; Koh ES, 2020, 'The (Co)Production of Difference in the Care of Patients With Cancer From Migrant Backgrounds', Qualitative Health Research, 30, pp. 1619 - 1631, http://dx.doi.org/10.1177/1049732320930699

Journal articles | 2020

Hnit SST; Yao M; Xie C; Ge G; Bi L; Jin S; Jiao L; Xu L; Long L; Nie H; Jin Y; Rogers L; Suchowerska N; Wong M; Liu T; De Souza P; Li Z; Dong Q, 2020, 'Transcriptional regulation of G2/M regulatory proteins and perturbation of G2/M Cell cycle transition by a traditional Chinese medicine recipe', Journal of Ethnopharmacology, 251, pp. 112526, http://dx.doi.org/10.1016/j.jep.2019.112526

Journal articles | 2020

Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Chua W; Ng W; Lee M; Roberts TL; de Souza P; Lee CS, 2020, 'Aberrant expression of RAD52, its prognostic impact in rectal cancer and association with poor survival of patients', International Journal of Molecular Sciences, 21, http://dx.doi.org/10.3390/ijms21051768

Journal articles | 2020

Jeffreys SA; Powter B; Balakrishnar B; Mok K; Soon P; Franken A; Neubauer H; Souza PD; Becker TM, 2020, 'Endocrine resistance in breast cancer: The role of estrogen receptor stability', Cells, 9, pp. 1 - 23, http://dx.doi.org/10.3390/cells9092077

Journal articles | 2020

Kato H; de Souza P; Kim SW; Lickliter JD; Naito Y; Park K; Kumar S; Mugundu GM; Bang YJ, 2020, 'Safety, Pharmacokinetics, and Clinical Activity of Adavosertib in Combination with Chemotherapy in Asian Patients with Advanced Solid Tumors: Phase Ib Study', Targeted Oncology, 15, pp. 75 - 84, http://dx.doi.org/10.1007/s11523-020-00701-5

Journal articles | 2020

Khan T; Scott KF; Becker TM; Lock J; Nimir M; Ma Y; De Souza P, 2020, 'The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?', Prostate Cancer, 2020, http://dx.doi.org/10.1155/2020/7938280

Journal articles | 2020

Lynch D; Powter B; Po JW; Cooper A; Garrett C; Koh ES; Sheridan M; van Gelder J; Darwish B; Mckechnie S; Bazina R; Jaeger M; Roberts TL; de Souza P; Becker TM, 2020, 'Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting', Applied Sciences (Switzerland), 10, http://dx.doi.org/10.3390/app10093338

Journal articles | 2020

Reardon DA; Brandes AA; Omuro A; Mulholland P; Lim M; Wick A; Baehring J; Ahluwalia MS; Roth P; Bähr O; Phuphanich S; Sepulveda JM; De Souza P; Sahebjam S; Carleton M; Tatsuoka K; Taitt C; Zwirtes R; Sampson J; Weller M, 2020, 'Effect of Nivolumab vs Bevacizumab in Patients with Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial', JAMA Oncology, 6, pp. 1003 - 1010, http://dx.doi.org/10.1001/jamaoncol.2020.1024

Journal articles | 2020

Sareen H; Garrett C; Lynch D; Powter B; Brungs D; Cooper A; Po J; Koh ES; Vessey JY; McKechnie S; Bazina R; Sheridan M; van Gelder J; Darwish B; Jaeger M; Roberts TL; De Souza P; Becker TM, 2020, 'The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients', Cancers, 12, pp. 1 - 16, http://dx.doi.org/10.3390/cancers12071831

Journal articles | 2020

Tjokrowidjaja A; Goldstein D; Hudson HM; Lord SJ; Gebski V; Clarke S; de Souza P; Motzer RJ; Lee CK, 2020, 'The impact of neutrophil-lymphocyte ratio on risk reclassification of patients with advanced renal cell cancer to guide risk-directed therapy', Acta Oncologica, 59, pp. 20 - 27, http://dx.doi.org/10.1080/0284186X.2019.1656342

Journal articles | 2020

Toh JWT; Lim SH; MacKenzie S; de Souza P; Bokey L; Chapuis P; Spring KJ, 2020, 'Association Between Microsatellite Instability Status and Peri-Operative Release of Circulating Tumour Cells in Colorectal Cancer', Cells, 9, http://dx.doi.org/10.3390/cells9020425

Journal articles | 2020

Wimmer M; Zauner R; Ablinger M; Pinõ´ n-Hofbauer J; Guttmann-Gruber C; Reisenberger M; Lettner T; Niklas N; Proell J; Sajinovic M; De Souza P; Hainzl S; Kocher T; Murauer EM; Bauer JW; Strunk D; Reichelt J; Mellick AS; Wally V, 2020, 'A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas', Cell Communication and Signaling, 18, http://dx.doi.org/10.1186/s12964-020-00550-9

Journal articles | 2020

de Souza P; Gao B; Voskoboynik M; Wilkinson K; Cooper A; Hoon S-N; Palmieri D; Cai S; Tian YE; Hsieh C-Y; Ma N; Xu C; Chen Y; Yang S; Zhang S, 2020, '574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours', Annals of Oncology, 31, pp. S490 - S490, http://dx.doi.org/10.1016/j.annonc.2020.08.688

Journal articles | 2020

de Souza PL; Capp AL; Chikhladze N; Mezvrishvili Z; Messina M; Mautner G, 2020, 'Phase I study of a novel S1P inhibitor, NOX66, in combination with radiotherapy in patients with metastatic castration-resistant prostate cancer.', Journal of Clinical Oncology, 38, pp. 5533 - 5533, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5533

Journal articles | 2019

Aghajani MJ; Cooper A; McGuire H; Jeffries T; Saab J; Ismail K; de Souza P; Bray V; Fazekas de St Groth B; Niles N; Roberts TL, 2019, 'Pembrolizumab for anaplastic thyroid cancer: a case study', Cancer Immunology, Immunotherapy, 68, pp. 1921 - 1934, http://dx.doi.org/10.1007/s00262-019-02416-7

Journal articles | 2019

Aghajani MJ; Roberts TL; Yang T; McCafferty CE; Caixeiro NJ; DeSouza P; Niles N, 2019, 'Elevated levels of soluble pd-l1 are associated with reduced recurrence in papillary thyroid cancer', Endocrine Connections, 8, pp. 1040 - 1051, http://dx.doi.org/10.1530/EC-19-0210

Journal articles | 2019

Basch EM; Scholz M; de Bono JS; Vogelzang N; de Souza P; Marx G; Vaishampayan U; George S; Schwarz JK; Antonarakis ES; O'Sullivan JM; Kalebasty AR; Chi KN; Dreicer R; Hutson TE; Dueck AC; Bennett AV; Dayan E; Mangeshkar M; Holland J; Weitzman AL; Scher HI, 2019, 'Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint', European Urology, 75, pp. 929 - 937, http://dx.doi.org/10.1016/j.eururo.2018.11.033

Journal articles | 2019

Broom A; Kirby E; Kokonavic R; Woodland L; Wyld D; de Souza P; Koh S; Lwin Z, 2019, 'Individualising difference, negotiating culture: Intersections of biography and cancer care', Health, http://dx.doi.org/10.1177/1363459319829192

Journal articles | 2019

Cao J; Zhang P; De Souza PL; Gao B; Voskoboynik M; Ji D; Shen W; Yang S; Zhou Y; Zhang R; Lickliter JD; Hoon S-N; Palmieri D; Cai S; Tian YE; Ma N; Xu C; Yang S; Zhang S; Xu B, 2019, 'Pooled analysis of phase I dose-escalation and dose cohort expansion studies of IMP4297, a novel PARP inhibitor, in Chinese and Australian patients with advanced solid tumors.', JOURNAL OF CLINICAL ONCOLOGY, 37, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.3059

Journal articles | 2019

Clarke J; Chu S-C; Siu LL; Machiels J-P; Markman B; Heinhuis K; Millward M; Lolkema M; Patel SP; Souza PD; Curigliano G; Santoro A; Brown M; Fleming R; Vezina H; He C; Rottey S, 2019, 'Abstract B057: BMS-986148, an anti-mesothelin antibody-drug conjugate (ADC), alone or in combination with nivolumab demonstrates clinical activity in patients with select advanced solid tumors', Molecular Cancer Therapeutics, 18, pp. B057 - B057, http://dx.doi.org/10.1158/1535-7163.targ-19-b057

Journal articles | 2019

Clingan PR; Ackland SP; Brungs D; de Souza P; Aghmesheh M; Garg MB; Ranson RD; Parker S; Jokela R; Ranson M, 2019, 'First-in-human phase I study of infusional and bolus schedules of Deflexifol, a novel 5-fluorouracil and leucovorin formulation, after failure of standard treatment', Asia-Pacific Journal of Clinical Oncology, 15, pp. 151 - 157, http://dx.doi.org/10.1111/ajco.13144

Journal articles | 2019

Ding PN; Becker T; Bray V; Chua W; Ma Y; Xu B; Lynch D; de Souza P; Roberts T, 2019, 'Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib', Thoracic Cancer, 10, pp. 1879 - 1884, http://dx.doi.org/10.1111/1759-7714.13154

Journal articles | 2019

Ding PN; Becker TM; Bray VJ; Chua W; Ma YF; Lynch D; Po J; Luk AWS; Caixeiro N; de Souza P; Roberts TL, 2019, 'The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study', Lung Cancer, 134, pp. 187 - 193, http://dx.doi.org/10.1016/j.lungcan.2019.06.021

Journal articles | 2019

Lim SHS; Ip E; Ng W; Chua W; Asghari R; Roohullah A; Descallar J; Henderson C; Spring K; de Souza P; King MT, 2019, 'Health-related quality of life during chemoradiation in locally advanced rectal cancer: Impacts and ethnic disparities', Cancers, 11, http://dx.doi.org/10.3390/cancers11091263

Journal articles | 2019

Naher S; Padinharakam S; Balakrishnar B; Chua W; Descallar J; Adams D; de Souza P; Harrison M; Lim S, 2019, 'Patterns of Presentation and Treatment Outcomes of Non–clear-cell Renal Cell Carcinoma and Sarcomatoid Renal Cell Carcinoma Patients in 2 Tertiary Referral Centers in Sydney, Australia', Clinical Genitourinary Cancer, 17, pp. e565 - e569, http://dx.doi.org/10.1016/j.clgc.2019.02.006

Journal articles | 2019

Nimir M; Ma Y; Jeffreys SA; Opperman T; Young F; Khan T; Ding P; Chua W; Balakrishnar B; Cooper A; Souza PD; Becker TM, 2019, 'Detection of AR-v7 in liquid biopsies of castrate resistant prostate cancer patients: A comparison of AR-v7 analysis in circulating tumor cells, circulating tumor RNA and exosomes', Cells, 8, http://dx.doi.org/10.3390/cells8070688

Journal articles | 2019

Panizza BJ; de Souza P; Cooper A; Roohullah A; Karapetis CS; Lickliter JD, 2019, 'Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46)', EBioMedicine, 50, pp. 433 - 441, http://dx.doi.org/10.1016/j.ebiom.2019.11.037

Journal articles | 2019

Po JW; Ma Y; Balakrishna B; Brungs D; Azimi F; De Souza P; Becker TM, 2019, 'Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status', PLoS ONE, 14, http://dx.doi.org/10.1371/journal.pone.0211866

Journal articles | 2019

Powderly J; Spira A; Gutierrez R; DiRenzo D; Udyavar A; Karakunnel JJ; Rieger A; Colabella J; Lai DW; de Souza P, 2019, 'Phase I evaluation of AB928, a novel dual adenosine receptor antagonist, combined with chemotherapy or AB122 (anti-PD-1) in patients (pts) with advanced malignancies', Annals of Oncology, 30, pp. v493 - v493, http://dx.doi.org/10.1093/annonc/mdz253.032

Journal articles | 2019

Singh P; de Souza P; Scott KF; Hall BM; Verma ND; Becker TM; Toh JWT; Sajinovic M; Spring KJ, 2019, 'Biomarkers in immune checkpoint inhibition therapy for cancer patients: what is the role of lymphocyte subsets and PD1/PD-L1?', Translational Medicine Communications, 4, http://dx.doi.org/10.1186/s41231-019-0032-9

Journal articles | 2019

Weller M; Reardon D; Brandes A; Sampson J; Mulholland P; Wick A; Baehring J; Ahluwalia M; Roth P; Bähr O; Phuphanich S; Sepulveda J; de Souza P; Sahebjam S; Potter V; Tatsuoka K; Taitt C; Zwirtes R; Omuro A; Lim M, 2019, 'ATIM-47. NIVOLUMAB VS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: EXPLORATORY ANALYSIS OF MGMT METHYLATION STATUS AND BASELINE CORTICOSTEROID USE', Neuro-Oncology, 21, pp. vi12 - vi12, http://dx.doi.org/10.1093/neuonc/noz175.045

Journal articles | 2018

Aghajani M; Graham S; McCafferty C; Shaheed CA; Roberts T; Desouza P; Yang T; Niles N, 2018, 'Clinicopathologic and Prognostic Significance of Programmed Cell Death Ligand 1 Expression in Patients with Non-Medullary Thyroid Cancer: A Systematic Review and Meta-Analysis', Thyroid, 28, pp. 349 - 361, http://dx.doi.org/10.1089/thy.2017.0441

Journal articles | 2018

Bi L; Xie C; Yao M; Thae Hnit SS; Vignarajan S; Wang Y; Wang Q; Xi Z; Xu H; Li Z; de Souza P; Tee A; Wong M; Liu T; Zhao X; Zhou J; Xu L; Dong Q, 2018, 'The histone chaperone complex FACT promotes proliferative switch of G0 cancer cells', International Journal of Cancer, 145, pp. 164 - 178, http://dx.doi.org/10.1002/ijc.32065

Journal articles | 2018

Brungs D; Aghmesheh M; de Souza P; Carolan M; Clingan P; Rose J; Ranson M, 2018, 'Safety and Efficacy of Oxaliplatin Doublet Adjuvant Chemotherapy in Elderly Patients With Stage III Colon Cancer', Clinical Colorectal Cancer, 17, pp. e549 - e555, http://dx.doi.org/10.1016/j.clcc.2018.05.004

Journal articles | 2018

Brungs D; Lynch D; Luk AWS; Minaei E; Ranson M; Aghmesheh M; Vine KL; Carolan M; Jaber M; De Souza P; Becker TM, 2018, 'Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer', World Journal of Gastroenterology, 24, pp. 810 - 818, http://dx.doi.org/10.3748/wjg.v24.i7.810

Journal articles | 2018

Campbell DH; Lund ME; Nocon AL; Cozzi PJ; Frydenberg M; De Souza P; Schiller B; Beebe-Dimmer JL; Ruterbusch JJ; Walsh BJ, 2018, 'Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0196017

Journal articles | 2018

Ding PN; Ma YF; Roberts TJ; Chua W; Bray VJ; Lynch D; Burke D; Souza PD; Becker TM, 2018, 'Droplet Digital PCR Based Detection of EGFR Mutations in Advanced Lung Cancer Patient Liquid Biopsies: A Comparison of Circulating Tumour DNA Extraction Kits', Journal of Molecular Biomarkers & Diagnosis, 09, http://dx.doi.org/10.4172/2155-9929.1000397

Journal articles | 2018

Harris BHL; Walsh JL; Neciunaite R; Manders P; Cooper A; De Souza P, 2018, 'Ring a ring o'roses, a patient with Kaposi's? Pazopanib, pazopanib, it might go away. Mediterranean (classic) Kaposi sarcoma responds to the tyrosine kinase inhibitor pazopanib after multiple lines of standard therapy', Clinical and Experimental Dermatology, 43, pp. 234 - 236, http://dx.doi.org/10.1111/ced.13302

Journal articles | 2018

Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Ng W; Lee M; de Souza P; Shin JS; Lee CS, 2018, 'Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis', BMC Cancer, 18, http://dx.doi.org/10.1186/s12885-018-4776-9

Journal articles | 2018

Po JW; Roohullah A; Lynch D; DeFazio A; Harrison M; Harnett PR; Kennedy C; de Souza P; Becker TM, 2018, 'Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin', Journal of Circulating Biomarkers, 7, http://dx.doi.org/10.1177/1849454418782617

Journal articles | 2018

Razdan A; de Souza P; Roberts TL, 2018, 'Role of microRNAs in treatment response in prostate cancer', Current Cancer Drug Targets, 18, pp. 929 - 944, http://dx.doi.org/10.2174/1568009618666180315160125

Journal articles | 2018

Roohullah A; Cooper A; Lomax AJ; Aung J; Barge A; Chow L; McHale M; Desai J; Whittle JR; Tran B; de Souza P; Horvath LG, 2018, 'A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers', Investigational New Drugs, 36, pp. 886 - 894, http://dx.doi.org/10.1007/s10637-018-0588-7

Journal articles | 2018

de Souza PL; Messina M; Minns I; Shavdia M; Chikhladze N; Kelly G, 2018, 'A phase 1 study of NOX66 in combination with carboplatin in patients with end stage solid tumours.', Journal of Clinical Oncology, 36, pp. 2585 - 2585, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.2585

Journal articles | 2018

de Souza PL; Wong S; Sewak S; Kotasek D; Keam B; Chung J; Erbeck N; Han J; Dezzani L; Ahmad Q; Mainwaring PN, 2018, 'Phase II study of sequential first-line pazopanib (PAZ) followed by everolimus (EVE) in patients (pts) with advanced or metastatic renal cell carcinoma (RCC) (CATChEz Study).', JOURNAL OF CLINICAL ONCOLOGY, 36, http://dx.doi.org/10.1200/JCO.2018.36.6_suppl.648

Journal articles | 2017

Ackland SP; Garg MB; Ranson M; Jokela R; Brungs D; Aghmesheh M; Tafreshi A; Ranson RD; Parker S; De Souza PL; Clingan PR, 2017, 'Deflexifol (a novel formulation of 5FU): Pharmacokinetics in a phase 1 trial in comparison to 5FU.', Journal of Clinical Oncology, 35, pp. 2530 - 2530, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2530

Journal articles | 2017

Aslan P; Clark W; Patel M; Vass J; Cade D; De Silva SJ; De Souza P, 2017, 'Renal function after selective internal radiation therapy (SIRT) with yttrium-90 (Y-90) resin microspheres in patients with primary renal cell carcinoma (RCC): The RESIRT study', European Urology Supplements, 16, pp. e630 - e631, http://dx.doi.org/10.1016/s1569-9056(17)30424-4

Journal articles | 2017

Aslan P; Clark W; Patel M; Vass J; Cade DN; de Silva SJ; de Souza PL, 2017, 'MP16-12 SELECTIVE INTERNAL RADIATION THERAPY (SIRT) WITH YTTRIUM-90 (Y-90) RESIN MICROSPHERES IN PATIENTS WITH PRIMARY RENAL CELL CARCINOMA (RCC): IMPACT ON RENAL FUNCTION AND QUALITY OF LIFE IN THE RESIRT STUDY', Journal of Urology, 197, http://dx.doi.org/10.1016/j.juro.2017.02.518

Journal articles | 2017

Brungs D; Aghmesheh M; de Souza P; Ng W; Chua W; Carolan M; Clingan P; Healey E; Rose J; Tubaro T; Ranson M, 2017, 'Sidedness is prognostic in locoregional colon cancer: An analysis of 9509 Australian patients', BMC Cancer, 17, pp. 251, http://dx.doi.org/10.1186/s12885-017-3255-z

Journal articles | 2017

Callari M; De Souza PL; Rawal A; Stenzel MH, 2017, 'The Effect of Drug Loading on Micelle Properties: Solid-State NMR as a Tool to Gain Structural Insight', Angewandte Chemie - International Edition, 56, pp. 8441 - 8445, http://dx.doi.org/10.1002/anie.201701471

Journal articles | 2017

Callari M; De Souza PL; Rawal A; Stenzel MH, 2017, 'The Effect of Drug Loading on Micelle Properties: Solid‐State NMR as a Tool to Gain Structural Insight', Angewandte Chemie, 129, pp. 8561 - 8565, http://dx.doi.org/10.1002/ange.201701471

Journal articles | 2017

Callari M; Wong S; Lu H; Aldrich-Wright J; De Souza P; Stenzel MH, 2017, 'Drug induced self-assembly of triblock copolymers into polymersomes for the synergistic dual-drug delivery of platinum drugs and paclitaxel', Polymer Chemistry, 8, pp. 6289 - 6299, http://dx.doi.org/10.1039/c7py01162h

Journal articles | 2017

Clark W; Aslan P; Patel M; Vass J; Cade D; de Silva S; De Souza P, 2017, 'The RESIRT study: feasibility and dosimetry considerations of selective internal radiation therapy (SIRT) using yttrium-90 (Y-90) resin microspheres in patients with primary renal cell carcinoma (RCC)', Journal of Vascular and Interventional Radiology, 28, pp. S164 - S164, http://dx.doi.org/10.1016/j.jvir.2016.12.1001

Journal articles | 2017

Clingan PR; Ackland SP; Ranson M; Brungs D; Aghmesheh M; Tafreshi A; Garg MB; Parker S; Henderson A; Jokela R; De Souza PL, 2017, 'Deflexifol (a novel formulation of 5FU): Phase 1 dose escalation study of infusional and bolus schedules after failure of standard treatment.', Journal of Clinical Oncology, 35, pp. 2529 - 2529, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2529

Journal articles | 2017

Clingan PR; Ackland SP; Ranson M; De Souza P; Tafreshi A; Aghmesheh M; Brungs D; Garg MB; Parker S; Jokela R, 2017, 'Phase 1 study of infusional or bolus deflexifol (a novel formulation of 5FU, folinic acid, and cyclodextrin) after failure of standard treatment.', Journal of Clinical Oncology, 35, pp. TPS812 - TPS812, http://dx.doi.org/10.1200/jco.2017.35.4_suppl.tps812

Journal articles | 2017

Del Re M; Fogli S; Derosa L; Massari F; De Souza P; Crucitta S; Bracarda S; Santini D; Danesi R, 2017, 'The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide', Cancer Treatment Reviews, 55, pp. 71 - 82, http://dx.doi.org/10.1016/j.ctrv.2017.03.001

Journal articles | 2017

Ho V; Chung L; Singh A; Lea V; Revoltar M; Lim SH; Tut TG; Ng W; Lee M; de Souza P; Shin JS; Lee CS, 2017, 'Early postoperative low expression of RAD50 in rectal cancer patients associates with disease-free survival', Cancers, 9, pp. 163, http://dx.doi.org/10.3390/cancers9120163

Journal articles | 2017

Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, 18, http://dx.doi.org/10.3390/ijms18051047

Journal articles | 2017

Reardon DA; Omuro A; Brandes AA; Rieger J; Wick A; Sepulveda J; Phuphanich S; de Souza P; Ahluwalia MS; Lim M; Vlahovic G; Sampson J, 2017, 'OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143', Neuro-Oncology, 19, pp. iii21 - iii21, http://dx.doi.org/10.1093/neuonc/nox036.071

Journal articles | 2017

Weller M; Butowski N; Tran DD; Recht LD; Lim M; Hirte H; Ashby L; Mechtler L; Goldlust SA; Iwamoto F; Drappatz J; O'Rourke DM; Wong M; Hamilton MG; Finocchiaro G; Perry J; Wick W; Green J; He Y; Turner CD; Yellin MJ; Keler T; Davis TA; Stupp R; Sampson JH; Campian J; Becker K; Barnett G; Nicholas G; Desjardins A; Benkers T; Wagle N; Groves M; Kesari S; Horvath Z; Merrell R; Curry R; O'Rourke J; Schuster D; Mrugala M; Jensen R; Trusheim J; Lesser G; Belanger K; Sloan A; Purow B; Fink K; Raizer J; Schulder M; Nair S; Peak S; Brandes A; Mohile N; Landolfi J; Olson J; Jennens R; DeSouza P; Robinson B; Crittenden M; Shih K; Flowers A; Ong S; Connelly J; Hadjipanayis C; Giglio P; Mott F; Mathieu D; Lessard N; Sepulveda SJ; Lövey J; Wheeler H; Inglis PL; Hardie C; Bota D; Lesniak M; Portnow J; Frankel B; Junck L; Thompson R; Berk L; McGhie J; Macdonald D; Saran F; Soffietti R; Blumenthal D; André de SBCM; Nowak A; Singhal N; Hottinger A; Schmid A; Srkalovic G; Baskin D; Fadul C; Nabors L; LaRocca R; Villano J; Paleologos N; Kavan P; Pitz M; Thiessen B, 2017, 'Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial', The Lancet Oncology, 18, pp. 1373 - 1385, http://dx.doi.org/10.1016/S1470-2045(17)30517-X

Journal articles | 2016

Caixeiro NJ; Byun HL; Descallar J; Levesque JV; De Souza P; Soon Lee C, 2016, 'Health professionals' opinions on supporting a cancer biobank: Identification of barriers to combat biobanking pitfalls', European Journal of Human Genetics, 24, pp. 626 - 632, http://dx.doi.org/10.1038/ejhg.2015.191

Journal articles | 2016

De Souza P; Aslan P; Clark W; Patel M; Vass J; Cade D; De Silva S, 2016, 'RESIRT: A phase 1 study of Selective Internal Radiation Therapy (SIRT) using Yttrium-90 (Y-90) resin microspheres in patients with primary Renal Cell Carcinoma (RCC)', European Urology Supplements, 15, pp. e1541 - e1542, http://dx.doi.org/10.1016/s1569-9056(16)30374-8

Journal articles | 2016

Ho V; Chung L; Revoltar M; Lim SH; Tut TG; Abubakar A; Henderson CJ; Chua W; Ng W; Lee M; De Souza P; Morgan M; Lee CS; Shin JS, 2016, 'MRE11 and ATM expression levels predict rectal cancer survival and their association with radiotherapy response', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0167675

Journal articles | 2016

Lee CK; Davies L; Gebski VJ; Lord SJ; Di Leo A; Johnston S; Geyer C; Cameron D; Press MF; Ellis C; Loi S; Marschner I; Simes J; De Souza P, 2016, 'Serum human epidermal growth factor 2 extracellular domain as a predictive biomarker for lapatinib treatment efficacy in patients with advanced breast cancer', Journal of Clinical Oncology, 34, pp. 936 - 944, http://dx.doi.org/10.1200/JCO.2015.62.4767

Journal articles | 2016

Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, 17, http://dx.doi.org/10.3390/ijms17081264

Journal articles | 2016

Powles TB; Escudier B; de Souza P; Chowdhury S; Pook D; Harmenberg U; Basappa N; Geynisman D; Merchan J; Redman BG; Ryan C; Goodman O; Ho T; Singh P; Lougheed J; Patel M; Knox JJ; Motzer RJ; Choueiri TK, 2016, 'Efficacy of cabozantinib (cabo) vs everolimus (eve) by metastatic site and tumor burden in patients (pts) with advanced renal cell carcinoma (RCC) in the phase 3 METEOR trial', Annals of Oncology, 27, pp. vi284, http://dx.doi.org/10.1093/annonc/mdw373.41

Journal articles | 2016

Toh JWT; de Souza P; Lim SH; Singh P; Chua W; Ng W; Spring KJ, 2016, 'The Potential Value of Immunotherapy in Colorectal Cancers: Review of the Evidence for Programmed Death-1 Inhibitor Therapy', Clinical Colorectal Cancer, 15, pp. 285 - 291, http://dx.doi.org/10.1016/j.clcc.2016.07.007

Journal articles | 2016

Wang H; Markman B; de Souza P; Dees EC; Gangadhar TC; Piha-Paul SA; Zamboni WC; Murphy C; Senderowicz A, 2016, 'A dose-escalation study of weekly intravenous CRLX301 in patients with advanced solid tumor malignancies', ANNALS OF ONCOLOGY, 27, http://dx.doi.org/10.1093/annonc/mdw368.56

Journal articles | 2016

de Souza P; Aslan P; Clark W; Patel M; Vass JA; Cade D; de Silva SJ, 2016, 'Phase 1 study of selective internal radiation therapy (SIRT) with yttrium-90 (Y-90) resin microspheres in patients (pts) with renal cell carcinoma (RCC): RESIRT', ANNALS OF ONCOLOGY, 27, http://dx.doi.org/10.1093/annonc/mdw373.31

Journal articles | 2016

de Souza P; Chua W; Clarke S; Goldstein D; Lee C, 2016, 'Inflammatory Markers Have a Role in Renal Cell Carcinoma Prognosis', European Urology Focus, 2, pp. 341 - 342, http://dx.doi.org/10.1016/j.euf.2016.04.007

Journal articles | 2015

Choueiri TK; Figueroa DJ; Fay AP; Signoretti S; Liu Y; Gagnon R; Deen K; Carpenter C; Benson P; Ho TH; Pandite L; De Souza P; Powles T; Motzer RJ, 2015, 'Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: Results from COMPARZ, a randomized controlled trial', Clinical Cancer Research, 21, pp. 1071 - 1077, http://dx.doi.org/10.1158/1078-0432.CCR-14-1993

Journal articles | 2015

De Souza PL; Lee CS, 2015, 'The Centre for Oncology Education and Research Translation (CONCERT) Biobank', Open Journal of Bioresources, 2, http://dx.doi.org/10.5334/ojb.ai

Journal articles | 2015

Hnit SST; Xie C; Yao M; Holst J; Bensoussan A; De Souza P; Li Z; Dong Q, 2015, 'P27^Kip1 signaling: Transcriptional and post-translational regulation', International Journal of Biochemistry and Cell Biology, 68, pp. 9 - 14, http://dx.doi.org/10.1016/j.biocel.2015.08.005

Journal articles | 2015

Lickliter JD; Panizza B; Karapetis CS; Gordon VA; Reddell PW; Lingard KT; Cusack RM; De Souza P, 2015, 'Phase 1 dose-escalation study of EBC-46 given by intratumoral injection to patients with refractory cutaneous and subcutaneous tumors.', Journal of Clinical Oncology, 33, pp. TPS2616 - TPS2616, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.tps2616

Journal articles | 2015

Lim SH; Chua W; Henderson C; Ng W; Shin JS; Chantrill L; Asghari R; Lee CS; Spring KJ; de Souza P, 2015, 'Predictive and prognostic biomarkers for neoadjuvant chemoradiotherapy in locally advanced rectal cancer', Critical Reviews in Oncology/Hematology, 96, pp. 67 - 80, http://dx.doi.org/10.1016/j.critrevonc.2015.05.003

Journal articles | 2015

Lim SH; Spring KJ; De Souza P; Mackenzie S; Bokey L, 2015, 'Circulating tumour cells and circulating nucleic acids as a measure of tumour dissemination in non-metastatic colorectal cancer surgery', European Journal of Surgical Oncology, 41, pp. 309 - 314, http://dx.doi.org/10.1016/j.ejso.2014.12.005

Journal articles | 2015

Morris MJ; Molina A; Small EJ; De Bono JS; Logothetis CJ; Fizazi K; De Souza P; Kantoff PW; Higano CS; Li J; Kheoh T; Larson SM; Matheny SL; Naini V; Burzykowski T; Griffin TW; Scher HI; Ryan CJ, 2015, 'Radiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results', Journal of Clinical Oncology, 33, pp. 1356 - 1363, http://dx.doi.org/10.1200/JCO.2014.55.3875

Journal articles | 2015

Mulders PFA; Smith MR; Fizazi K; Saad F; Sternberg CN; Miller K; Logothetis CJ; Shore ND; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Souza P; De Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE; Ryan CJ, 2015, '556 Abiraterone acetate improves overall survival in chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC): Impact of crossover and baseline prognostic factors in the COU-AA-302 final analysis', European Urology Supplements, 14, pp. e556 - e556a, http://dx.doi.org/10.1016/s1569-9056(15)60549-8

Journal articles | 2015

Nayak L; Brandes A; Omuro A; Rieger J; Wick A; Phuphanich S; Sumrall A; Sahebjam S; Ahluwalia M; de Souza P; Sepulveda JM; Maio M; Grauer O; Vlahovic G; Baehring J; Dastani H; Latek R; Coric V; Reardon D, 2015, 'QOL-07DESCRIPTION OF CLINICAL AND PATIENT REPORTED OUTCOMES ASSESSMENTS FROM A PHASE 3, MULTICENTER, RANDOMIZED TRIAL EVALUATING NIVOLUMAB MONOTHERAPY VERSUS BEVACIZUMAB IN RECURRENT GLIOBLASTOMA: CHECKMATE-143', Neuro-Oncology, 17, pp. v189.2 - v189, http://dx.doi.org/10.1093/neuonc/nov230.07

Journal articles | 2015

Ryan CJ; Smith MR; Fizazi K; Saad F; Mulders PFA; Sternberg CN; Miller K; Logothetis CJ; Shore ND; Small EJ; Carles J; Flaig TW; Taplin ME; Higano CS; de Souza P; de Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE, 2015, 'Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): Final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study', The Lancet Oncology, 16, pp. 152 - 160, http://dx.doi.org/10.1016/S1470-2045(14)71205-7

Journal articles | 2015

Saad F; Shore N; Van Poppel H; Rathkopf DE; Smith MR; De Bono JS; Logothetis CJ; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin TA; De Porre P; Londhe A; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2015, 'Impact of bone-targeted therapies in chemotherapy-naïve metastatic castration-resistant prostate cancer patients treated with abiraterone acetate: Post hoc analysis of study COU-AA-302', European Urology, 68, pp. 570 - 577, http://dx.doi.org/10.1016/j.eururo.2015.04.032

Journal articles | 2015

Scarano W; De Souza P; Stenzel MH, 2015, 'Dual-drug delivery of curcumin and platinum drugs in polymeric micelles enhances the synergistic effects: A double act for the treatment of multidrug-resistant cancer', Biomaterials Science, 3, pp. 163 - 174, http://dx.doi.org/10.1039/c4bm00272e

Journal articles | 2015

Sengupta S; Grimison P; Hayne D; Williams S; Chambers S; Desouza P; Stockler M; McJannett M; Toner G; Davis ID, 2015, 'The Australian and New Zealand Urogenital and Prostate (ANZUP) Cancer Trials Group - A new co-operative cancer trials group in genitourinary oncology', BJU International, 115, pp. 856 - 858, http://dx.doi.org/10.1111/bju.12925

Journal articles | 2015

Tognela A; Spring KJ; Becker T; Caixeiro NJ; Bray VJ; Yip PY; Chua W; Lim SH; de Souza P, 2015, 'Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective', Critical Reviews in Oncology/Hematology, 93, pp. 90 - 102, http://dx.doi.org/10.1016/j.critrevonc.2014.10.001

Journal articles | 2015

Tut TG; Lim S; Dissanayake I; Descallar J; Chua W; Ng W; De Souza P; Bokey L; Shin J-S; Soon Lee C, 2015, '14. Upregulated PLK1 expression confers radiation resistance and poor patient survival outcomes in rectal cancer', Pathology, 47, pp. S104 - S105, http://dx.doi.org/10.1097/01.pat.0000461623.74546.8a

Journal articles | 2015

Tut TG; Lim SHS; Dissanayake IU; Descallar J; Chua W; Ng W; De Souza P; Shin JS; Lee CS, 2015, 'Upregulated polo-like kinase 1 expression correlates with inferior survival outcomes in rectal cancer', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0129313

Journal articles | 2014

Becker TM; Caixeiro NJ; Lim SH; Tognela A; Kienzle N; Scott KF; Spring KJ; De Souza P, 2014, 'New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use', International Journal of Cancer, 134, pp. 2523 - 2533, http://dx.doi.org/10.1002/ijc.28516

Journal articles | 2014

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; De Souza P; Becker TM, 2014, 'Circulating tumour cells - A bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, 33, pp. 747 - 756, http://dx.doi.org/10.1007/s10555-014-9502-8

Journal articles | 2014

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; de Souza P; Becker TM, 2014, 'Circulating tumour cells-a bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-014-9502-8

Journal articles | 2014

Callari M; Aldrich-Wright JR; De Souza PL; Stenzel MH, 2014, 'Polymers with platinum drugs and other macromolecular metal complexes for cancer treatment', Progress in Polymer Science, 39, pp. 1614 - 1643, http://dx.doi.org/10.1016/j.progpolymsci.2014.05.002

Journal articles | 2014

Choueiri TK; Figueroa DJ; Liu Y; Gagnon RC; Deen KC; Carpenter C; Bartlett-Pandite AN; De Souza P; Powles T; Motzer RJ, 2014, 'Correlation of PDL1 tumor expression and treatment outcomes in patients with renal cell carcinoma (RCC) receiving tyrosine kinase inhibitors: COMPARZ study analysis.', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.4_suppl.416

Journal articles | 2014

Ho TH; Choueiri TK; D'Amelio A; Hsieh J; De Souza PL; Deen KC; Langmuir PB; Liu Y; Motzer RJ, 2014, 'The effect of SETD2 mutation (mts) on histone 3 lysine 36 trimethylation (H3K36me3) and correlation with clinical outcome in patients (pts) with metastatic clear cell renal cell carcinoma (ccRCC) enrolled in COMPARZ', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.4583

Journal articles | 2014

Hovey E; De Souza P; Marx G; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft P; Abdi E; Lloyd A, 2014, 'Phase III, randomized, double-blind, placebo-controlled study of modafinil for fatigue in patients treated with docetaxel-based chemotherapy', Supportive Care in Cancer, 22, pp. 1233 - 1242, http://dx.doi.org/10.1007/s00520-013-2076-0

Journal articles | 2014

Lee C; Davies L; Marschner I; Gebski V; Lord S; Di Leo A; Johnston SRD; Geyer CE; Cameron DA; Press MF; Ellis CE; Loi S; Simes J; De Souza P, 2014, 'Prognostic, predictive, and surrogate value of HER2 extracellular domain (ECD) for progression-free survival (PFS) in advanced breast cancer treated with lapatinib (lap): A meta-analysis.', JOURNAL OF CLINICAL ONCOLOGY, 32, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.630

Journal articles | 2014

Lim SH; Becker TM; Chua W; Caixeiro NJ; Ng WL; Kienzle N; Tognela A; Lumba S; Rasko JEJ; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer', Cancer Letters, 346, pp. 24 - 33, http://dx.doi.org/10.1016/j.canlet.2013.12.019

Journal articles | 2014

Lim SH; Delaney GP; Descallar J; Sayaloune P; Papadatos G; de Souza P, 2014, 'Outcomes of ethnic minority groups with node-positive, non-metastatic breast cancer in two tertiary referral centers in Sydney, Australia.', PLoS One, 9, pp. e95852, http://dx.doi.org/10.1371/journal.pone.0095852

Journal articles | 2014

Lim SHS; Ardern-Holmes S; McCowage G; De Souza P, 2014, 'Systemic therapy in neurofibromatosis type 2', Cancer Treatment Reviews, 40, pp. 857 - 861, http://dx.doi.org/10.1016/j.ctrv.2014.05.004

Journal articles | 2014

Lim SHS; Becker TM; Chua W; Ng WL; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer', Journal of Clinical Pathology, 67, pp. 848 - 853, http://dx.doi.org/10.1136/jclinpath-2014-202499

Journal articles | 2014

Lim SHS; Chua W; Cheng C; Descallar J; Ng W; Solomon M; Bokey L; Wong K; Lee MT; De Souza P; Shin JS; Lee CS, 2014, 'Effect of neoadjuvant chemoradiation on tumor-infiltrating/associated lymphocytes in locally advanced rectal cancers', Anticancer Research, 34, pp. 6505 - 6513

Journal articles | 2014

Rathkopf DE; Smith MR; De Bono JS; Logothetis CJ; Shore ND; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Van Poppel H; Carles J; Flaig TW; Efstathiou E; Yu EY; Higano CS; Taplin ME; Griffin TW; Todd MB; Yu MK; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ; Saad F, 2014, 'Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302)', European Urology, 66, pp. 815 - 825, http://dx.doi.org/10.1016/j.eururo.2014.02.056

Journal articles | 2014

Sebaratnam DF; Martin LK; Venugopal SS; Mangos G; Freiman J; de Souza P; Farnsworth A; Cheung K; Scolyer RA; Murrell DF, 2014, 'Diffuse melanosis cutis in the setting of BRAF^V⁶⁰⁰^E metastatic melanoma', International Journal of Dermatology, 53, pp. 1409 - 1411, http://dx.doi.org/10.1111/ijd.12614

Journal articles | 2014

Shore N; Rathkopf D; Smith MR; de Bono JS; Logothetis C; de Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2014, 'PD27-01 EFFICACY AND LONG-TERM SAFETY ANALYSIS OF STUDY COU-AA-302: ABIRATERONE ACETATE PLUS PREDNISONE IN CHEMOTHERAPY-NAÏVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER', Journal of Urology, 191, http://dx.doi.org/10.1016/j.juro.2014.02.2100

Journal articles | 2014

Tse BWC; Jovanovic L; Nelson CC; De Souza P; Power CA; Russell PJ, 2014, 'From Bench to Bedside: Immunotherapy for Prostate Cancer', BioMed Research International, 2014, http://dx.doi.org/10.1155/2014/981434

Journal articles | 2014

de Souza P, 2014, 'Convenor's Welcome', Asia-Pacific Journal of Clinical Oncology, 10, pp. 1 - 2, http://dx.doi.org/10.1111/ajco.12232

Journal articles | 2014

Mak G; Chin M; Nahar N; De Souza P, 2014, 'Cutaneous metastasis of prostate carcinoma treated with radiotherapy: A case presentation', , http://dx.doi.org/10.1186/1756-0500-7-505

Journal articles | 2013

De Souza P; Begbie S; Hovey L; Rashid P; Aslan P; Malouf D; Awad N; Clements A; Hadley A; Galettis P; O'malley L; Melbourne W; Johnson L; Tran K; Lynch W, 2013, 'Phase II Trial of Intravesical Gemcitabine and Biomarker Evaluation in Patients with Superficial Urothelial Carcinoma of the Bladder', World Journal of Cancer Research, 1, pp. 131 - 137, http://dx.doi.org/10.1166/wjcr.2013.1014

Journal articles | 2013

Fox P; Hudson M; Brown C; Lord S; Gebski V; De Souza P; Lee CK, 2013, 'Markers of systemic inflammation predict survival in patients with advanced renal cell cancer', British Journal of Cancer, 109, pp. 147 - 153, http://dx.doi.org/10.1038/bjc.2013.300

Journal articles | 2013

Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Bucci J; De Souza P; Mallesara G; Murrell DF, 2013, 'Use of cetuximab as an adjuvant agent to radiotherapy and surgery in recessive dystrophic epidermolysis bullosa with squamous cell carcinoma', British Journal of Dermatology, 169, pp. 208 - 210, http://dx.doi.org/10.1111/bjd.12272

Journal articles | 2013

Lim S; de Souza P, 2013, 'Imatinib in neurofibromatosis type 2', BMJ case reports, 2013, http://dx.doi.org/10.1136/bcr-2013-010274

Journal articles | 2013

Lim S; de Souza P, 2013, 'Imatinib in neurofibromatosis type 2.', BMJ case reports, 2013

Journal articles | 2013

Motzer RJ; Hutson TE; Cella D; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; Souza P; Merchan JR; Boleti E; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Sternberg CN; Deen K; McCann L; Hackshaw MD; Crescenzo R; Pandite LN; Choueiri TK, 2013, 'Pazopanib versus sunitinib in metastatic renal-cell carcinoma', New England Journal of Medicine, 369, pp. 722 - 731, http://dx.doi.org/10.1056/NEJMoa1303989

Journal articles | 2013

Paz-Ares L; Bálint B; De Boer RH; Van Meerbeeck JP; Wierzbicki R; De Souza P; Galimi F; Haddad V; Sabin T; Hei YJ; Pan Y; Cottrell S; Hsu CP; Ramlau R, 2013, 'A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer', Journal of Thoracic Oncology, 8, pp. 329 - 337, http://dx.doi.org/10.1097/JTO.0b013e31827ce554

Journal articles | 2013

Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore N; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302).', Journal of Clinical Oncology, 31, pp. 5009 - 5009, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5009

Journal articles | 2013

Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore ND; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy.', Journal of Clinical Oncology, 31, pp. 5 - 5, http://dx.doi.org/10.1200/jco.2013.31.6_suppl.5

Journal articles | 2013

Ryan C; Smith M; de Bono J; Molina A; Logothetis D; De Souza P; et A, 2013, 'Abiraterone in metastatic prostate cancer without previous chemotherapy', New England Journal of Medicine, 368, pp. 138 - 148, http://dx.doi.org/10.1056/NEJMoa1209096

Journal articles | 2013

Saad F; Shore ND; Van Poppel H; Rathkopf D; Smith MR; de Bono JS; Logothetis C; de Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '713 ABIRATERONE ACETATE IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS WITHOUT PRIOR CHEMOTHERAPY - INTERIM ANALYSIS OF THE COU-AA-302 PHASE 3 TRIAL', Journal of Urology, 189, http://dx.doi.org/10.1016/j.juro.2013.02.272

Journal articles | 2013

Scarano W; Duong HTT; Lu HX; De Souza PL; Stenzel MH, 2013, 'Folate Conjugation to Polymeric Micelles via Boronic Acid Ester to Deliver Platinum Drugs to Ovarian Cancer Cell Lines', Biomacromolecules, 14, pp. 962 - 975, http://dx.doi.org/10.1021/bm400121q

Journal articles | 2013

Suttle A; De Souza P; Arumugham T, 2013, 'Bayesian methods for pharmacokinetic/pharmacodynamic modeling of pazopanib-induced increases in blood pressure and transaminases', Journal of Clinical Pharmacology, 53, pp. 377 - 384, http://dx.doi.org/10.1002/jcph.16

Journal articles | 2013

Van Poppel H; Rathkopf D; Smith MR; De Bono JS; Logothetis CJ; Shore ND; De Souza P; Fizazi K; Mulders PFA; Mainwaring P; Hainsworth JD; Beer TM; North S; Fradet Y; Griffin T; Park YC; Kheoh T; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, '97 Updated interim analysis (IA): Results of randomized phase 3 study COU-AA-302 of abiraterone acetate (AA) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) without prior chemotherapy', European Urology Supplements, 12, pp. e97 - e98, http://dx.doi.org/10.1016/s1569-9056(13)60589-8

Journal articles | 2013

Weber MF; Smith DP; O'Connell DL; Patel MI; de Souza PL; Sitas F; Banks E, 2013, 'Risk factors for erectile dysfunction in a cohort of 108 477. Australian men', Medical Journal of Australia, 199, pp. 107 - 111, http://dx.doi.org/10.5694/mja12.11548

Journal articles | 2013

Won ACM; Gurney H; Marx G; De Souza P; Patel MI, 2013, 'Primary treatment of the prostate improves local palliation in men who ultimately develop castrate-resistant prostate cancer', BJU INTERNATIONAL, 112, pp. E250 - E255, http://dx.doi.org/10.1111/bju.12169

Journal articles | 2013

Won ACM; Gurney H; Marx G; De Souza P; Patel MI, 2013, 'Primary treatment of the prostate improves local palliation in men who ultimately develop castrate-resistant prostate cancer', BJU International, 112, http://dx.doi.org/10.1111/bju.12169

Journal articles | 2013

Yee GPC; De Souza P; Khachigian LM, 2013, 'Current and potential treatments for cervical cancer', Current Cancer Drug Targets, 13, pp. 205 - 220, http://dx.doi.org/10.2174/1568009611313020009

Journal articles | 2013

Yee GPC; De Souza PL; Khachigian LM, 2013, 'Reducing invasion potential of cervical cancer cells via targeted knockdown of c-Jun.', Journal of Clinical Oncology, 31, pp. e22005 - e22005, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e22005

Journal articles | 2012

Boyer M; Horwood K; Pavlakis N; De Souza P; Millward MJ; Stein B; Johnston M; Abell F; Rischin D, 2012, 'Efficacy of erlotinib in patients with advanced Non-small-cell Lung Cancer (NSCLC): Analysis of the Australian subpopulation of the TRUST study.', Asia-Pacific Journal of Clinical Oncology, 8, pp. 248 - 254, http://dx.doi.org/10.1111/j.1743-7563.2012.01540.x

Journal articles | 2012

Cameron BA; Bennett B; Li H; Boyle F; deSouza P; Wilcken N; Friedlander M; Goldstein D; Lloyd AR, 2012, 'Post-cancer fatigue is not associated with immune activation or altered cytokine production', Annals of Oncology, 23, pp. 2890 - 2895, http://dx.doi.org/10.1093/annonc/mds108

Journal articles | 2012

Coupe N; Harrison M; Chua W; De Souza P, 2012, 'Biomarkers for tyrosine kinase inhibitors in renal cell cancer', Translational Andrology and Urology, 1, pp. 216 - 222, http://dx.doi.org/10.3978/j.issn.2223-4683.2012.10.01

Journal articles | 2012

Goldstein D; Bennett BK; Webber K; Boyle F; De Souza P; Wilcken NRC; Scott E; Toppler R; Murie P; O''Malley L; Mccourt J; Friedlander M; Hickie IB; Lloyd AR, 2012, 'Cancer-related fatigue in women with breast cancer: outcomes of a 5 year prospective cohort study.', Journal of Clinical Oncology, 30, pp. 1805 - 1812, http://dx.doi.org/10.1200/JCO.2011.34.6148

Journal articles | 2012

Hovey E; de Souza P; Marx G; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Kraft P; Lloyd A, 2012, 'PHASE III, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF MODAFINIL FOR FATIGUE IN PATIENTS TREATED WITH DOCETAXEL-BASED CHEMOTHERAPY', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 44 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2012

Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial', JOURNAL OF CLINICAL ONCOLOGY, 30, http://dx.doi.org/10.1200/jco.2012.30.5_suppl.211

Journal articles | 2012

Hovey EJ; De Souza PL; Marx GM; Parente P; Rapke T; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', J Clin Oncol, 30, pp. 211, http://www.ncbi.nlm.nih.gov/pubmed/27967925

Journal articles | 2012

Hovey EJ; De Souza PL; Marx GM; Rapke T; Parente P; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', Journal of Clinical Oncology, 30, pp. e15152 - e15152, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15152

Journal articles | 2012

Huynh VT; Binauld SDM; De souza P; Stenzel MH, 2012, 'Acid Degradable Cross-Linked Micelles for the Delivery of Cisplatin: A Comparison with Nondegradable Cross-Linker', Chemistry of materials, 24, pp. 3197 - 3211, http://dx.doi.org/10.1021/cm301556b

Journal articles | 2012

Huynh VT; Quek JY; De Souza P; Stenzel MH, 2012, 'Block copolymer micelles with pendant bifunctional chelator for platinum drugs: Effect of spacer length on the viability of tumor cells', Biomacromolecules, 13, pp. 1010 - 1023, http://dx.doi.org/10.1021/bm2017299

Journal articles | 2012

Kim M; Li M; Intong LRA; Tran K; Melbourne W; Marucci D; Inder S; de Souza P; Mallesara G; Murrell DF, 2012, 'USE OF CETUXIMAB AS AN ADJUVANT AGENT TO RADIOTHERAPY AND SURGERY IN RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA WITH SQUAMOUS CELL CARCINOMA', WOUND REPAIR AND REGENERATION, 20, pp. A60 - A60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308945000030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2012

Lee CK; Marschner IC; Simes RJ; Voysey M; Egleston B; Hudes G; De Souza P, 2012, 'Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus', Clinical Cancer Research, 18, pp. 3188 - 3196, http://dx.doi.org/10.1158/1078-0432.CCR-11-3137

Journal articles | 2012

Lemech CR; Fontela A; Arkenau H-T; Chin MTM; Li S; Liauw WS; Thomas D; De Souza PL, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours.', Journal of Clinical Oncology, 30, pp. e13585 - e13585, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e13585

Journal articles | 2012

Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'CORRELATION OF GRADE & HORMONE-RECEPTOR STATUS WITH STAGE IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 335 - 335, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2012

Lim S; Descallar J; Sayaloune P; Delaney G; Papadatos G; de Souza P, 2012, 'TUMOUR:NODE RATIO IN NODE-POSITIVE, NON-METASTATIC BREAST CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 37 - 37, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2012

Lim SH; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney G, 2012, 'Outcomes of Ethnic Minority Groups With Node-Positive, Non-Metastatic Breast Cancer in a Tertiary Referral Centre in Sydney', Annals of Oncology, 23, pp. ix100 - ix100, http://dx.doi.org/10.1016/s0923-7534(20)32823-4

Journal articles | 2012

Motzer R; Hutson TE; Reeves J; Hawkins R; Guo J; Nathan P; Staehler M; de Souza P; Merchan JR; Fife K; Jin J; Jones R; Uemura H; De Giorgi U; Harmenberg U; Wang J; Cella D; McCann L; Deen K; Choueiri TK, 2012, 'Randomized, Open-Label, Phase III Trial Of Pazopanib Versus Sunitinib In First-Line Treatment Of Patients With Metastatic Renal Cell Carcinoma (MRCC): Results of the Comparz Trial', Annals of Oncology, 23, pp. ixe13 - ixe13, http://dx.doi.org/10.1016/s0923-7534(20)34325-8

Journal articles | 2012

Ryan CJ; Morris M; Molina A; Piulats JR; De Souza P; Li J; Kheoh T; de Bono JS; Larson S; Griffin T; Matheny S; Naini V; Scher HI; Small E, 2012, 'Association of Radiographic Progression-Free Survival (RPFS) Adapted from Prostate Cancer Working Group 2 (PCWG2) Consensus Criteria (APCWG2) with Overall Survival (OS) in Patients (PTS) with Metastatic Castration-Resistant Prostate Cancer (MCRPC): Results from COU-AA-302', Annals of Oncology, 23, pp. ix294 - ix295, http://dx.doi.org/10.1016/s0923-7534(20)33459-1

Journal articles | 2012

Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; Kheoh TS; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', Journal of Clinical Oncology, 30, pp. LBA4518 - LBA4518, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.lba4518

Journal articles | 2012

Thientosapol E; Nelson M; Descallar J; de Souza P, 2012, 'AN EXPLORATORY ANALYSIS OF THE LONGITUDINAL RELATIONSHIPS BETWEEN PROSTATE SPECIFIC ANTIGEN AND THE INFLAMMATORY MARKERS C-REACTIVE PROTEIN AND ERYTHROCYTE SEDIMENTATION RATE', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 58 - 58, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2012

Xu C; Xue Z; Bing NX; King K; De Souza P; et A, 2012, 'Concomitant use of pazopanib and simvastatin increases the risk of transaminase elevations in patients with cancer', Annals of Oncology, 23 Sep 2012, pp. 2470 - 2471, http://dx.doi.org/10.1093/annonc/mds249

Journal articles | 2011

De Souza P; Saad F, 2011, 'Bone health in prostate cancer', Expert Review of Endocrinology and Metabolism, 6, pp. 317 - 321, http://dx.doi.org/10.1586/eem.11.4

Journal articles | 2011

Glass SM; Huang L; King K; Ragone LJ; Ball HA; De Souza PL; Wagstaff J; Spraggs CF; Mooser VE; Pandite LN; Xu C, 2011, 'Genetic evaluation of fatigue in pazopanib-treated patients (pts) with advanced renal cell carcinoma (RCC).', J Clin Oncol, 29, pp. e15072, http://www.ncbi.nlm.nih.gov/pubmed/28020421

Journal articles | 2011

Gu W; Gaborieau M; Huynh VT; De Souza PL; Stenzel MH, 2011, 'Functionalization of microspheres with malonates using Michael Addition as a pathway to create a drug delivery system for platinum drugs for the treatment of liver cancer', Polymer, 52, pp. 5993 - 6002, http://dx.doi.org/10.1016/j.polymer.2011.10.054

Journal articles | 2011

Howes J; De Souza PL; Weston L; Huang LJ; Howes LG, 2011, 'Pharmacokinetics of phenoxodiol, a novel isoflavone, following intravenous administration to patients with advanced cancer', BMC Clinical Pharmacology, 11, pp. 1 - 8, http://dx.doi.org/10.1186/1472-6904-11-1

Journal articles | 2011

Huynh VT; De Souza PL; Stenzel MH, 2011, 'Polymeric micelles with pendant dicarboxylato chelating ligands prepared via a michael addition for cis -platinum drug delivery', Macromolecules, 44, pp. 7888 - 7900, http://dx.doi.org/10.1021/ma2016503

Journal articles | 2011

Li S; de Souza P, 2011, 'Ras isoprenylation and pAkt inhibition by zoledronic acid and fluvastatin enhances paclitaxel activity in T24 bladder cancer cells', Cancers, 3, pp. 662 - 674, http://dx.doi.org/10.3390/cancers3010662

Journal articles | 2011

Manners S; Galettis P; De Souza PL, 2011, 'Conditions causing gemcitabine crystallization', Journal of Oncology Pharmacy Practice, 17, pp. 395 - 399, http://dx.doi.org/10.1177/1078155210385033

Journal articles | 2011

Won CM; Gurney H; Marx G; De Souza P; Patel MI, 2011, 'PRIMARY TREATMENT OF THE PROSTATE IMPROVES LOCAL PALLIATION IN MEN WHO ULTIMATELY DEVELOP CASTRATE RESISTANT PROSTATE CANCER.', JOURNAL OF ENDOUROLOGY, 25, pp. A256 - A257, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296792201146&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2011

Xu C; Bing NX; Ball HA; Rajagopalan D; Sternberg CN; Hutson T; De Souza PL; Xue ZG; McCann L; King KS; Ragone LJ; Whittaker JC; Spraggs C; Cardon LR; Mooser VE; Pandite LN, 2011, 'Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes', Journal of Clinical Oncology, 29, pp. 2557 - 2564, http://dx.doi.org/10.1200/JCO.2010.32.9110

Journal articles | 2010

De Souza PL; Mellado B; Pfister C; Rosenthal M; Castellano DE; Weber D; Ferrara S; Shaik N; Tan E; Patterson SA, 2010, 'Randomized phase II trial of patupilone plus prednisone versus docetaxel plus prednisone in patients with chemotherapy-naive, metastatic, castrate-resistant prostate cancer(CRPC)', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.4553

Journal articles | 2010

De Souza PL; North S; Bolger GB; Spiridonidis H; Lim R; Khoo KS; Phillips J; Fujimori M, 2010, 'A phase II trial of weekly i.v. KW-2170 in advanced castrate-resistant prostate cancer', Asia-Pacific Journal of Clinical Oncology, 6, pp. 292 - 297, http://dx.doi.org/10.1111/j.1743-7563.2010.01328.x

Journal articles | 2010

De Souza PL; Russell PJ; Kearsley J; Howes LG, 2010, 'Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer.', Nutrition Reviews, 68, pp. 542 - 555, http://dx.doi.org/10.1111/j.1753-4887.2010.00314.x

Journal articles | 2010

Duong HTT; Huynh TV; De Souza PL; Stenzel M, 2010, 'Core-Crosslinked Micelles synthesized by Clicking Bifunctional Pt(IV) Anticancer Drugs to Isocyanates', Biomacromolecules, 11, pp. 2290 - 2299, http://dx.doi.org/10.1021/bm100396s

Journal articles | 2010

Hutson TE; Davis ID; MacHiels JP; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Urology, 184, pp. 1303, http://dx.doi.org/10.1016/j.juro.2010.06.075

Journal articles | 2010

Hutson TE; Davis ID; Machiels JPH; De Souza PL; Rottey S; Hong BF; Epstein RJ; Baker KL; McCann L; Crofts T; Pandite L; Figlin RA, 2010, 'Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma', Journal of Clinical Oncology, 28, pp. 475 - 480, http://dx.doi.org/10.1200/JCO.2008.21.6994

Journal articles | 2010

Khasraw M; Pavlakis N; Mccowatt S; Underhill C; Begbie S; De Souza PL; Boyce A; Parnis F; Lim V; Harvie R; Marx G, 2010, 'Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer', Annals of Oncology, 21, pp. 1302 - 1307, http://dx.doi.org/10.1093/annonc/mdp524

Journal articles | 2010

Scott KF; Sajinovic M; Hein J; Nixdorf S; Galettis P; Liauw WS; De Souza PL; Dong Q; Graham GG; Russell PJ, 2010, 'Emerging roles for phospholipase A2 enzymes in cancer', Biochimie, 92, pp. 601 - 610

Journal articles | 2010

Webber K; Goldstein D; Bennett BK; Boyle FM; De Souza PL; Wilcken N; Friedlander M; Lloyd AR, 2010, 'Influence of fatigue after breast cancer adjuvant theraphy on health care utilization and percieved needs', JOURNAL OF CLINICAL ONCOLOGY, 28, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.9047

Journal articles | 2010

Yang S; De Souza PL; Alemao E; Purvis J, 2010, 'Quality of life in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha', British Journal of Cancer, 102, pp. 1456 - 1460, http://dx.doi.org/10.1038/sj.bjc.6605647

Journal articles | 2009

Crombie C; Burns W; Karapetis C; Lowenthal RM; Kirsten F; Davidson J; Abell F; Reece W; Iglesias J; De Souza PL, 2009, 'Randomized phase II trial of gemcitabine and either day 1 or day 8 carboplatin for advanced non-small-cell lung cancer: Is thrombocytopenia predictable?', Asia-Pacific Journal of Clinical Oncology, 5, pp. 24 - 31

Journal articles | 2009

Figlin R; De Souza PL; McDermott D; Dutcher J; Berkenblit A; Thiele A; Krygowski M; Strahs A; Feingold J; Boni J; Hudes G, 2009, 'Analysis of PTEN and HIF-1 alpha and Correlation With Efficacy in Patients With Advanced Renal Cell Carcinoma Treated With Temsirolimus Versus Interferon-alpha', Cancer, 115, pp. 3651 - 3660

Journal articles | 2009

McPherson RAC; Galettis PT; De Souza PL, 2009, 'Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells', British Journal of Cancer, 100, pp. 649 - 655, http://dx.doi.org/10.1038/sj.bjc.6604920

Journal articles | 2009

Simonetti AC; Humberto de Lima Melo J; Eleutério de Souza PR; Bruneska D; Luiz de Lima Filho J, 2009, 'Immunological's host profile for HPV and Chlamydia trachomatis, a cervical cancer cofactor', Microbes and Infection, 11, pp. 435 - 442, http://dx.doi.org/10.1016/j.micinf.2009.01.004

Journal articles | 2008

Amaral MB; Buchholz I; Freire-Maia B; Reher P; De Souza PEA; De Marigo HA; Martins CR; Horta MCR, 2008, 'Advanced osteosarcoma of the maxilla: A case report', Medicina Oral, Patologia Oral y Cirugia Bucal, 13

Journal articles | 2008

Goldstein D; Bennett B; Cameron B; Boyle F; DeSouza P; Wilcken N; Friedlander M; Scott E; Hickie I; Lloyd AAM, 2008, 'A prospective cohort study of fatigue after adjuvant therapy for breast cancer: Association with hematologic, endocrine, and immune parameters', JOURNAL OF CLINICAL ONCOLOGY, 26, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.9596

Journal articles | 2008

Hutson TE; Davis ID; Machiels JH; de Souza PL; Baker K; Bordogna W; Westlund R; Crofts T; Pandite L; Figlin RA, 2008, 'Biomarker analysis and final efficacy and safety results of a phase II renal cell carcinoma trial with pazopanib (GW786034), a multi-kinase angiogenesis inhibitor', JOURNAL OF CLINICAL ONCOLOGY, 26, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.5046

Journal articles | 2008

de Souza PL; Radulovic S; Beck J; Pendergrass K; Siddique N; Dutcher JP; Berkenblit A; Thiele A; Krygowski M; Hudes GR, 2008, 'Characterization of hyperglycemia, hypercholesterolemia, and hyperlipidemia in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-α', Journal of Clinical Oncology, 26, pp. 5116 - 5116, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.5116

Journal articles | 2007

Friedlander ML; Buck MD; Wyld D; Findlay M; Fitzharris B; De Souza PL; Davies TM; Kalimi G; Allan S; Perez DM; Harnett PH, 2007, 'Phase II study of carboplatin followed by sequential gemcitabine and paclitaxel as first-line treatment for advanced ovarian cancer', International Journal of Gynecological Cancer, 17, pp. 350 - 358

Journal articles | 2007

Grimison PS; Galettis P; Metharom E; De Souza PL; Links MJ; Liauw WS; Manners S; Jelinek M, 2007, 'Randomized crossover study evaluating the effect of gemcitabine infusion dose rate : evidence of auto-induction of gemcitabine accumulation', Journal of Clinical Oncology, 25, pp. 5704 - 5709

Journal articles | 2007

Harnett PH; Buck MD; Beale P; Goldrick AJ; Allan S; Fitzharris B; De Souza PL; Links MR; Kalimi G; Davies TM; Stuart-Harris R, 2007, 'Phase II study of gemcitabine and oxaliplatin in patients with recurrent ovarian cancer: an Australian and New Zealand Gynaecological Oncology Group study', International Journal of Gynecological Cancer, 17, pp. 359 - 366

Journal articles | 2007

Hutson TE; Davis ID; Machiels JP; de Souza PL; Hong BF; Rottey S; Baker KL; Crofts T; Pandite L; Figlin R, 2007, 'Pazopanib (GW786034) is active in metastatic renal cell carcinoma (RCC): Interim results of a phase II randomized discontinuation trial (RDT)', Journal of Clinical Oncology, 25, pp. 5031 - 5031, http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5031

Journal articles | 2007

de Souza P; Maart K; Laurell A; Hawkins RE; Berkenblit A; Galand L; Thiele A; Strahs A; Feingold J; Hudes G, 2007, '4011 POSTER Results of a phase 3, randomized study of patients with advanced renal cell carcinoma (RCC) and poor prognostic features treated with temsirolimus, interferon-a or the combination of temsirolimus + interferon-a', European Journal of Cancer Supplements, 5, pp. 282 - 283, http://dx.doi.org/10.1016/s1359-6349(07)71079-0

Journal articles | 2006

De Souza PL; Liauw WS; Links MJ; Pirabhahar S; Kelly G; Lowes LG, 2006, 'Phase I and pharmacokinetic study of weekly NV06 (Phenoxodioltrade mark), a novel isoflav-3-ene, in patients with advanced cancer', Cancer Chemotherapy and Pharmacology, 58, pp. 427 - 433

Journal articles | 2006

Gan HK; Mitchell P; Galettis P; Davis I; Cebon J; De Souza PL; Links MJ, 2006, 'A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors', Cancer Chemotherapy and Pharmacology, 58, pp. 157 - 164

Journal articles | 2006

Graham PH; Clark C; Abell F; Browne L; Capp A; Clingan PR; De Souza PL; Fox C; Links MJ, 2006, 'Concurrent-phase boost high-dose radiation therapy for non-small-cell lung cancer with or without cisplatin chemotherapy', Journal of Medical Imaging and Radiation Oncology, 50, pp. 342 - 348, http://dx.doi.org/10.1111/j.1440-1673.2006.01597.x

Journal articles | 2004

Rosen L; Gordon D; Tchekmedyian N; Yanagihara R; Hirsh V; Krzakowski M; Pawlicki M; De Souza PL; Zheng M; Urbanowitz G; Reitsma D; Seaman J, 2004, 'Long-term efficacy and safety of zoledronic acid in the treatment ofskeletal metastases in patients with nonsmall cell lung carcinoma andother solid tumors - A randomized, phase III, double-blind,placebo-controlled trial', Cancer, 100, pp. 2613 - 2621

Journal articles | 2003

Rosen LS; Gordon D; Tchekmedyian S; Yanagihara R; Hirsh V; Krzakowski M; Pawlicki M; de Souza P; Zheng M; Urbanowitz G; Reitsma D; Seaman JJ, 2003, 'Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial - The zoledronic acid lung cancer and other solid tumors study group', Journal of Clinical Oncology, 21, pp. 3150 - 3157, http://dx.doi.org/10.1200/JCO.2003.04.105

Journal articles | 2003

Souquet PJ; Price A; Jaworski M; Burillon JP; Aubert D; Fernandez O; Lewis C; De Souza P; Bosque L; Rodrigues Pereira J; Kolec V; Marel M; Astoul P; Jounieaux A; Riou R; Tack V; Deppermann KM; Gatzmeier U; Koschel G; Kreuser ED; Schlimok G; Von Pawel J; Isokangas OP; Mattson K; Torrecillas L; Lira Puerto V; Barroso N; Van Klaveren R; Gallardo D; Utraka B; Barnardt P; Tan EH; Sevilla Garcia I; Moreno Nogueira JA; Betticher D; Stahel R; Wernli M; Shih JF; Clark P; Harper P; Price A, 2003, 'Erratum: GLOB-1: A prospective randomised clinical phase III trial comparing vinorelbine-cisplatin with vinorelbine-ifosfamide-cisplatin in metastatic non-small-cell lung cancer patients (Annals of Oncology) (2002) vol. 13 (1853-1861))', Annals of Oncology, 14, pp. 347, http://dx.doi.org/10.1093/annonc/mdg083

Journal articles | 2001

Diamond TH; Winters J; Smith A; De Souza P; Kersley JH; Lynch WJ; Bryant C, 2001, 'The anti osteo porotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade - A double blind, randomized, placebo-controlled crossover study', CANCER, 92, pp. 1444 - 1450, http://dx.doi.org/10.1002/1097-0142(20010915)92:6<1444::AID-CNCR1468>3.0.CO;2-M

Journal articles | 2001

Diamond TH; Winters J; Smith A; De Souza P; Kersley JH; Lynch WJ; Bryant C, 2001, 'The antiosteoporotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade: A double blind, randomized, placebo-controlled crossover study', Cancer, 92, pp. 1444 - 1450, http://dx.doi.org/10.1002/1097-0142(20010915)92:6<1444::AID-CNCR1468>3.0.CO;2-M

Journal articles | 2001

Liauw W; Links M; Pirabhahar S; Husband A; Kelly G; De Souza PL, 2001, 'Phase I trial of weekly NV-06 (Phenoxodiol (TM)), a novel isoflavonoid, in patients with advanced cancer.', CLINICAL CANCER RESEARCH, 7, pp. 3694S - 3694S, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172121800205&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles | 2000

Cohen RM; Mueller SC; Haden K; De Souza PL, 2000, 'Phase I study of weekly vinorelbine in combination with weekly paclitaxel in adult patients with advanced refractory cancer', Cancer Investigation, 18, pp. 422 - 428, http://dx.doi.org/10.3109/07357900009032813

Journal articles | 1997

De Souza PL; Castillo M; Myers CE, 1997, 'Enhancement of paclitaxel activity against hormone-refractory prostate cancer cells in vitro and in vivo by quinacrine', British Journal of Cancer, 75, pp. 1593 - 1600, http://dx.doi.org/10.1038/bjc.1997.272

Journal articles | 1997

De Souza PL; Cooper MR; Imondi AR; Myers CE, 1997, '9-Aminocamptothecin: A topoisomerase I inhibitor with preclinical activity in prostate cancer', Clinical Cancer Research, 3, pp. 287 - 294

Journal articles | 1996

Stea S; Bachelor T; Cooper M; De Souza P; Koenig K; Bolton WK, 1996, 'Disposition and bioavailability of ceftazidime after intraperitoneal administration in patients receiving continuous ambulatory peritoneal dialysis', Journal of the American Society of Nephrology, 7, pp. 2399 - 2402

Journal articles | 1995

De Souza PL; Friedlander ML, 1995, 'Humoral hypercalcemia associated with adenocarcinoma of the rectum: A case report and review of the literature', American Journal of Clinical Oncology: Cancer Clinical Trials, 18, pp. 126 - 129, http://dx.doi.org/10.1097/00000421-199504000-00006

Journal articles | 1994

De Souza P; Friedlander M; Wilde C; Kirsten F; Ryan M, 1994, 'Hypersensitivity reactions to etoposide: A report of three cases and review of the literature', American Journal of Clinical Oncology: Cancer Clinical Trials, 17, pp. 387 - 389, http://dx.doi.org/10.1097/00000421-199410000-00005

Journal articles | 1993

De Souza P; Smith RD; Hall J; Gurney H; Harnett PR, 1993, 'A cost-utility approach to the use of 5-fluorouracil and levamisole as adjuvant chemotherapy for Dukes' C colonic carcinoma [5]', Medical Journal of Australia, 158, pp. 866, http://dx.doi.org/10.5694/j.1326-5377.1993.tb137685.x

Journal articles | 1993

de Souza P, 1993, 'Medical management of miscarriage with RU486.', Med J Aust, 159, pp. 491, https://www.ncbi.nlm.nih.gov/pubmed/8292160

Journal articles | 1992

De Souza PL; Friedlander ML, 1992, 'Prognostic factors in ovarian cancer', Hematology/Oncology Clinics of North America, 6, pp. 761 - 781, http://dx.doi.org/10.1016/s0889-8588(18)30309-5

Journal articles | 1992

Friedlander M; De Souza P; Segelov E, 1992, 'Risk factors, epidemiology, screening, and prognostic factors in female genital cancer', Current Opinion in Oncology, 4, pp. 913 - 922, http://dx.doi.org/10.1097/00001622-199210000-00016
Preprints | 2023

Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; De Souza P; Spring KJ, 2023, Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and are Predictive of Response in Locally Advanced Rectal Cancer, , http://dx.doi.org/10.20944/preprints202306.1821.v1

Conference Papers | 2022

Gu S; de Souza PL; Shi Y; Han W; Luo S; Chen J; Day D; Frentzas S; Park JJ; Shao G; Wu S; Fang M; Haydon AM; Sun S; Lei K; Ding L; Zuo R; Gan X; Zhao Y; Chen X, 2022, 'A phase I dose-escalation and expansion study of HBM4003, an anti-CTLA-4 heavy chain only monoclonal antibody, in patients with advanced solid tumors', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 03 June 2022 - 07 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000863680300865&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Gu S; de Souza PL; Shi Y; Han W; Luo S; Chen J; Day D; Frentzas S; Park JJ; Shao G; Wu S; Fang M; Haydon AM; Sun S; Lei K; Ding L; Zuo R; Gan X; Zhao Y; Chen X, 2022, 'A phase I dose-escalation and expansion study of HBM4003, an anti-CTLA-4 heavy chain only monoclonal antibody, in patients with advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. 2641 - 2641, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.2641

Conference Abstracts | 2022

Lee DH; Roohullah A; Cho BC; Lee S-H; Lemech C; De Souza P; Millward M; Choi J; Park KE; Kim E; Kim NY; Shin YK; Han J-Y, 2022, 'A phase I-II multicenter, open-label, dose-escalation study to evaluate the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of ABN401 in patients with advanced solid tumors and dose-expansion in patients with non-small cell lung cancer harboring c-MET dysregulation', in ANNALS OF ONCOLOGY, ELSEVIER, ELECTR NETWORK, Vol. 33, pp. S1096 - S1096, presented at Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), ELECTR NETWORK, 09 September 2022 - 13 September 2022, http://dx.doi.org/10.1016/j.annonc.2022.07.1320

Conference Papers | 2022

Lee DH; Roohullah A; Cho BC; Lemech CR; De Souza PL; Millward M; Choi JY; Park KE; Kim NY; Kim E; Lee S; Kim Y; Shin Y; Han J-Y, 2022, 'A phase 1 dose-escalation study of the ABN401 (c-MET inhibitor) in patients with solid tumors.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 03 June 2022 - 07 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000863680300998&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Lee DH; Roohullah A; Cho BC; Lemech CR; de Souza PL; Millward M; Choi JY; Park KE; Kim NY; Kim E; Lee S; Kim Y; Shin YOUNGKEE; Han J-Y, 2022, 'A phase 1 dose-escalation study of the ABN401 (c-MET inhibitor) in patients with solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. 3105 - 3105, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.3105

Conference Papers | 2022

Richardson GE; Tolcher AW; Morris MF; De Souza PL; Hamid A; She X; Zhu L; Wang H; Zheng S; Liu G; Li Y; Du FF; Fischkoff S; Gong H; Zha J; Luo P, 2022, 'Phase 1 study of ADG126, a novel masked anti-CTLA-4 SAFEbody, that combines tumor-localized activation with strong T-reg depletion and soft ligand blocking in patients with advanced solid tumors.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, pp. E17601 - E17601, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 03 June 2022 - 07 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000863680303552&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Vasselli JR; Frentzas S; Weickhardt AJ; de Souza PL; Tang J; Wyant T; Amit I; Ofran Y; Knickerbocker A, 2022, 'Trial in progress: A phase 1-2, first-in-human, open label, dose escalation and expansion study of AU-007, a monoclonal antibody that binds to IL-2 and inhibits IL-2Rα binding, in patients with advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. TPS2671 - TPS2671, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.tps2671

Conference Papers | 2021

de Souza P; Park J; Day D; Frentzas S; Haydon AM; Ji J; de Assis MM; Chen X; Gan X; Tao X; Zuo R; Ross G; Lu L, 2021, 'A phase I dose-escalation study of HBM4003: An anti-CTLA-4 heavy-chain-only mAb', in ANNALS OF ONCOLOGY, ELSEVIER, ELECTR NETWORK, pp. S855 - S855, presented at Congress of the European-Society-for-Medical-Oncology (ESMO), ELECTR NETWORK, 16 September 2021 - 21 September 2021, http://dx.doi.org/10.1016/j.annonc.2021.08.1399

Preprints | 2020

Aghajani M; Yang T; Schmitz U; James A; McCafferty CE; Souza PD; Niles N; Roberts T, 2020, Epithelial-to-Mesenchymal Transition and its Association with PD-L1 and CD8 T cells in Thyroid Cancer, , http://dx.doi.org/10.21203/rs.3.rs-34509/v1

Conference Papers | 2020

Shah MM; Bodocian H; Zauner R; Sajinovic M; De Souza P; Wally V; Mellick AS, 2020, 'MIR-10B AS A MARKER FOR DISSEMINATED DISEASE IN RDEB-LINKED SCCS', in ACTA DERMATO-VENEREOLOGICA, ACTA DERMATO-VENEREOLOGICA, pp. 60 - 61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000568327600162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2020

Wimmer M; Zauner R; Ablinger M; Pinon-Hofbauer J; Guttmann-Gruber C; Reisenberger M; Lettner T; Niklas N; Proell J; Sajinovic M; De Souza P; Hainzl S; Murauer EM; Bauer JW; Strunk D; Reichelt J; Mellick AS; Wally V, 2020, 'MIRNA-10B MARKS AGGRESSIVE SQUAMOUS CELL CARCINOMAS IN RDEB', in ACTA DERMATO-VENEREOLOGICA, ACTA DERMATO-VENEREOLOGICA, pp. 35 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000568327600097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints | 2020

Wimmer M; Zauner R; Ablinger M; Piñón-Hofbauer J; Guttmann-Gruber C; Reisenberger M; Lettner T; Niklas N; Proell J; Sajinovic M; De Souza P; Hainzl S; Kocher T; Murauer EM; Bauer JW; Strunk D; Reichelt J; Mellick AS; Wally V, 2020, MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotype, , http://dx.doi.org/10.1101/2020.02.05.934109

Conference Papers | 2019

Kotasek D; Coward J; de Souza PL; Underhill C; Jin X; Li B; Xia Y; Prawira A, 2019, 'A phase I dose escalation and dose expansion study of the anti-programmed cell death-1 (PD-1) antibody AK105.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.e14006

Conference Abstracts | 2019

Powderly JD; de Souza PL; Gutierrez R; Horvath L; Seitz L; Ashok D; Park A; Walters MJ; Karakunnel JJ; Berry W; Rieger A; Garofalo A; Lai DW; Chaudhry A, 2019, 'AB928, a novel dual adenosine receptor antagonist, combined with chemotherapy or AB122 (anti-PD-1) in patients (pts) with advanced tumors: Preliminary results from ongoing phase I studies.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.2604

Conference Papers | 2018

Bang Y-J; De Souza P; Kim S-W; Lickliter J; Naito Y; Park K; Kumar S; Mugundu GM; Kato H, 2018, 'Abstract B183: The WEE1 inhibitor AZD1775 in combination with chemotherapy in Asian patients with advanced solid tumors: a phase Ib study', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. B183 - B183, http://dx.doi.org/10.1158/1535-7163.targ-17-b183

Conference Papers | 2018

Ding PN; Becker T; Bray VJ; Chua W; Ma YF; Luk A; Po J; Lynch D; Caixeiro N; de Souza P; Roberts TL, 2018, 'Longitudinal analysis of circulating biomarkers to monitor advanced EGFR mutated (EGFR+) non-small cell lung cancer (NSCLC)', in Annals of oncology : official journal of the European Society for Medical Oncology, OXFORD UNIV PRESS, Munich, GERMANY, pp. viii660, presented at 43rd ESMO Congress (ESMO), Munich, GERMANY, 19 October 2018 - 23 October 2018, http://dx.doi.org/10.1093/annonc/mdy303.033

Conference Abstracts | 2018

Rachumalla PR; Carson E; Cooper A; Wilkinson K; Asghari R; Adams D; Ng W; Chua W; Roohullah A; De Souza P, 2018, 'Retrospective analysis of clinical characteristics and outcomes for patients enrolled in oncology phase 0 and phase 1 clinical trials at Liverpool Cancer Therapy Centre', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 14, pp. 168 - 169, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200283&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Posters | 2018

Rachumalla PR; Descallar J; Pal A; Wilson BE; Xuan W; Kiely BE; Mok K; Moylan E; Balakrishnar B; Adams D; Harvey S; Harrison M; Tognela A; Asghari R; DellaFiorentina S; De Souza P; Yap M; Lim K; Delaney G; Papadatos G; Boxer M; Vinod S; Lee CI, 2018, 'Is serum CA15-3 useful for assessing disease progression during systemic therapy in patients with metastatic breast cancer (MBC)?', Vol. 14, pp. 168 - 168, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200282&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2017

Bergin ART; Hovey E; Lloyd A; Marx G; Parente P; Rapke T; de Souza P, 2017, 'Docetaxel-related fatigue in men with metastatic prostate cancer: a descriptive analysis', in Supportive Care in Cancer, pp. 2871 - 2879, http://dx.doi.org/10.1007/s00520-017-3706-8

Conference Abstracts | 2017

Carson E; Cooper A; De Souza P; Chua W, 2017, 'Retrospective Analysis of Clinical Characteristics and Outcomes for Patients Enrolled on Oncology Phase I Clinical Trials at Liverpool Hospital Cancer Therapy Centre', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 13, pp. 117 - 117, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413954500150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2017

Lim SH-S; Ip E; Chua W; Ng W; Henderson C; Shin J-S; Harris BHL; Barberis A; Cowley M; De Souza PL; Spring K, 2017, 'Serum microRNA expression during neoadjuvant chemoradiation for rectal cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.e15081

Conference Abstracts | 2016

Brungs D; Healey E; Rose J; Tubaro T; Ng W; Chua W; Carolan M; de Souza P; Aghmesheh M; Ranson M, 2016, 'Adjuvant chemotherapy for stage III colorectal cancer in the elderly', in Annals of Oncology, Vol. 27, pp. vi182, http://dx.doi.org/10.1093/annonc/mdw370.101

Conference Papers | 2016

Lim SH; De Souza P; Chua W; Ng W; Harris B; Cowley MJ; Spring K, 2016, 'Change in serum microRNA expression during neoadjuvant chemoradiation for rectal cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at 107th Annual Meeting of the American-Association-of-Cancer-Research (AACR), LA, New Orleans, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1942

Conference Papers | 2016

Markman B; De Souza PL; Dees EC; Gangadhar TC; Cooper A; Roohullah A; Boolell V; Zamboni W; Murphy C; Senderowicz AM; Wang H, 2016, 'A phase 1 study of CRLX301, a novel nanoparticle-drug conjugate (NDC) containing docetaxel (DOC), in patients with refractory solid tumors.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 03 June 2016 - 07 June 2016, http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.2526

Conference Abstracts | 2016

Revoltar M; Shin J-S; Lim S; Tut T-G; Dissanayake I; Descallar J; Ho V; Chua W; Ng W; Lee M; Henderson C; De Souza P; Morgan M; Lee CS, 2016, 'Early marker of DNA damage response, atm, as a predictor of clinical outcome following radiotherapy in rectal cancer patients.', in Pathology, England, Vol. 48 Suppl 1, pp. S153, England, http://dx.doi.org/10.1016/j.pathol.2015.12.417

Conference Papers | 2016

Zamboni WC; Markman B; de Souza P; Dees EC; Gangadhar T; Eliasof S; Murphy C; Senderowicz A; Wang H, 2016, 'Abstract 2047: Pharmacokinetics (PK) of CRLX301, a novel nanoparticle-drug conjugate (NDC) containing the payload docetaxel, in patients with refractory solid tumors', in Cancer Research, American Association for Cancer Research (AACR), pp. 2047 - 2047, http://dx.doi.org/10.1158/1538-7445.am2016-2047

Conference Abstracts | 2015

Basch EM; Sholz MC; De Bono JS; Vogelzang NJ; De Souza PL; Marx GM; Vaishampayan UN; George S; Schwarz JK; Antonarakis ES; O'Sullivan JM; Kelabasty AR; Chi KN; Dreicer R; Hutson TE; Mangeshkar M; Holland JS; Weitzman A; Scher HI, 2015, 'Final analysis COMET-2: Cabozantinib (Cabo) versus mitoxantrone/prednisone (MP) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with moderate to severe pain who were previously treated with docetaxel(D) and abiraterone (A) and/or enzalutamide (E)', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, Vol. 33, presented at Genitourinary Cancers Symposium, FL, Orlando, 26 February 2015 - 28 February 2015, http://dx.doi.org/10.1200/jco.2015.33.7_suppl.141

Conference Abstracts | 2015

De Souza P; Smith MR; Fizazi K; Saad F; Mulders PFA; Sternberg CN; Miller K; Logothetis CJ; Shore N; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Bono JS; Griffin TW; De Porre P; Yu MK; Park YC; Li J; Kheoh T; Naini V; Molina A; Rathkopf DE; Ryan CJ, 2015, 'Final analysis of the randomised, phase 3, COU-AA-302 study of abiraterone acetate (AA) in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (mCRPC)', in BJU INTERNATIONAL, WILEY-BLACKWELL, AUSTRALIA, Adelaide, Vol. 115, pp. 21 - 22, presented at 68th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, AUSTRALIA, Adelaide, 11 April 2015 - 14 April 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351395100042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2015

Lim S; Chua W; Ng W; Descallar J; Bokey L; Spring K; De Souza P, 2015, 'Presence of circulating tumour cells and correlation with inflammatory markers in non-metastatic rectal cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 51, pp. S391 - S391, presented at European Cancer Congress, AUSTRIA, Vienna, http://dx.doi.org/10.1016/S0959-8049(16)31092-9

Conference Abstracts | 2015

Lim S; Ng W; Chua W; Descallar J; Spring K; De Souza P, 2015, 'Quality of life and circulating tumour cells in patients treated with neoadjuvant chemoradiation for rectal cancer - is there a link?', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 51, pp. S224 - S224, presented at European Cancer Congress, AUSTRIA, Vienna, http://dx.doi.org/10.1016/S0959-8049(16)30648-7

Conference Abstracts | 2015

Lim SH; Ng W; Chua W; Descallar J; Spring K; De Souza P, 2015, 'Psychological parameters and circulating tumor cells in locally advanced rectal cancer', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 57 - 57, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000357957300039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2015

Lim SH; Spring K; Chua W; Ng W; Descallar J; Ma Y; Becker TM; De Souza P, 2015, 'Circulating Tumor Cells in Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, TX, San Antonio, Vol. 93, pp. E522 - E523, presented at 57th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), TX, San Antonio, 18 October 2015 - 21 October 2015, http://dx.doi.org/10.1016/j.ijrobp.2015.07.1883

Conference Presentations | 2015

Padinharakam S; Chua W; Lim S; Karikios D; Adams D; Della-Fiorentina S; Desouza P; Moylan E; Harrison M; Descallar J; Balakrishnar B, 2015, 'Patterns of care and outcomes among sarcomatoid renal cell carcinoma patients in South Western Sydney', Vol. 11, pp. 180 - 180, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800331&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2015

Ryan CJ; Smith MR; Fizazi K; Saad F; Sternberg CN; Logothetis C; Small EJ; Carles J; Flaig TW; Taplin M-E; Higano CS; De Souza PL; De Bono JS; Griffin TW; De Porre P; Park YC; Li J; Kheoh TS; Molina A; Rathkopf DE, 2015, 'Impact of crossover and baseline prognostic factors on overall survival (OS) with abiraterone acetate (AA) in the COU-AA-302 final analysis.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, presented at Genitourinary Cancers Symposium, FL, Orlando, 26 February 2015 - 28 February 2015, http://dx.doi.org/10.1200/jco.2015.33.7_suppl.142

Conference Papers | 2015

Spring K; Lim S; Descallar J; Ng W; Chua W; de Souza P; Bokey L; MacKenzie S, 2015, 'Circulating tumour cell release in the peri-operative setting during curative colorectal cancer surgery', in Annals of Oncology, Oxford University Press (OUP), Barcelona, SPAIN, presented at ESMO 17th World Congress on Gastrointestinal Cancer, Barcelona, SPAIN, 01 July 2015 - 04 July 2015, http://dx.doi.org/10.1093/annonc/mdv233.297

Conference Papers | 2014

Lim SH-S; Shin J-S; Tut TG; Ng WTW; Chug W; Dissanayake IU; Spring K; Ng W; Bokey L; De Souza P; Lee CS, 2014, 'Polo-like kinase 1 as a biomarker in rectal cancers', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e14542

Conference Papers | 2014

Lim SH; Shin J-S; Tut TG; Ng WTW; Chua W; Dissanayake IU; Spring KJ; Bokey EL; Ng W; de Souza P; Lee CS, 2014, 'POLO-LIKE KINASE 1 AS A BIOMARKER IN RECTAL CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 60 - 60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2014

Sardjono C; Bower J; McCloud P; Mainwaring P; Sewak S; Wong S; Kotasek D; Lee SH; Chung JS; Sanmugarajah J; Troon S; Yip D; Singh N; Crump D; de Souza P, 2014, 'A PHASE II STUDY OF SEQUENTIAL THERAPY WITH PAZOPANIB FOLLOWED BY EVEROLIMUS IN METASTATIC RENAL CELL CANCER - STUDY UPDATE', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 65 - 65, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500059&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2014

Yu EY; Saad F; Londhe A; Shore ND; Van Poppel H; Rathkopf DE; Smith MR; Logothetis C; De Souza PL; Fizazi K; Mulders PFA; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Small EJ; Scher HI; Griffin TW; Yu MK; Ryan CJ, 2014, 'Association of alkaline phosphatase (ALP) with clinical outcomes in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, presented at Genitourinary Cancers Symposium, CA, San Francisco, 30 January 2014 - 01 February 2014, http://dx.doi.org/10.1200/jco.2014.32.4_suppl.27

Conference Papers | 2013

Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore N; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302)', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419601610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2013

Rathkopf DE; Smith MR; De Bono JS; Logothetis C; Shore ND; De Souza PL; Fizazi K; Mulders P; Mainwaring PN; Hainsworth JD; Beer TM; North SA; Fradet Y; Griffin TW; Park YC; Kheoh TS; Small EJ; Scher HI; Molina A; Ryan CJ, 2013, 'Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, presented at Genitourinary Cancers Symposium of the Conquer-Cancer-Foundation of American-Society-of-Clinical-Oncology (ASCO), FL, Orlando, 14 February 2013 - 16 February 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333679600009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2013

Yee GPC; De Souza PL; Khachigian LM, 2013, 'Reducing invasion potential of cervical cancer cells via targeted knockdown of c-Jun', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419605150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2013

de Souza P; Rathkopf D; Smith M; Mulders P; Mainwaring P; North S; Griffin T; Park Y; Molina A; Ryan C, 2013, 'Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in study COU-AA-302for metastatic castration-resistant prostate cancer', in BJU INTERNATIONAL, WILEY-BLACKWELL, pp. 13 - 13, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000321969100032&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2012

Hovey EJ; De Souza P; Marx G; Parente P; Rapke T; et A, 2012, 'Phase III, randomised, double-blind, placebo-controlled study of Modafinil for fatigue in patients treated with Docetaxel-based chemotherapy', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia Pty Ltd, Australia, pp. 26 - 26, presented at ANZUP Annual Scientific Meeting, State of the art Multi-Disciplinary Care in Urological Cancers, Sydney Darling Harbour, 15 July 2012 - 17 July 2012, http://dx.doi.org/10.1111/j.1743-7563.2012.01574_3.x

Conference Papers | 2012

Hovey EJ; De Souza PL; Marx GM; Rapke T; Parente P; Hill A; Bonaventura A; Michele A; Craft PS; Abdi EA; Lloyd AR, 2012, 'Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318009803130&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2012

Lemech C; Fontela A; Arkenau H; Chin M; Li S; Liauw WS; Thomas D; De Souza P, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours', in Journal of clinical oncology - official journal of the American Society of Clinical Oncology, American Society of Clinical Oncology, New York, pp. e13585 - e13585, presented at ASCO Annual Meeting, Chicago, USA, 01 June 2012 - 05 June 2012, http://meeting.ascopubs.org/gca?gca=ascomtg%3B30%2F15_suppl%2Fe13585&allch=&submit=Go#abstr-1

Conference Papers | 2012

Lim S; Descallar J; Sayaloune P; Delaney GP; Papadatos G; De Souza P, 2012, 'Tumour:node ratio in node-positive, non-metastatic breast cancer', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia, Australia, pp. 8 37-37; 2 SI AUG 2012, presented at ANZUP Annual Scientific Meeting

Conference Papers | 2012

Lim S; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney GP, 2012, 'Outcomes of ethnic minority groups with node-positive, non-metastatic breast cancer in a tertiary referral centre in Sydney', in Annals of Oncology, Oxford Univ Press, Oxford, England, pp. 23 100-100; 9 SEP 2012, presented at ESMO Congress Vienna

Conference Papers | 2012

Lim SH; Descallar J; Sayaloune P; Papadatos G; De Souza P; Delaney G, 2012, 'OUTCOMES OF ETHNIC MINORITY GROUPS WITH NODE-POSITIVE, NON-METASTATIC BREAST CANCER IN A TERTIARY REFERRAL CENTRE IN SYDNEY', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, AUSTRIA, Vienna, pp. 100 - 100, presented at 37th Congress of the European-Society-for-Medical-Oncology (ESMO), AUSTRIA, Vienna, 28 September 2012 - 02 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309409000256&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2012

Melbourne W; Tran K; Johnson LA; De Souza P; Lynch W, 2012, 'hENT1 expression in human urothelium; evaluating hENT1 prognostic potential for intravesical Gemcitabine treatment outcome in patients with superficial urothelial carcinoma', in BJU International, Urological Society of Australia and New Zealand, Darwin, pp. 109 40-40; 4 SI APR 2012, presented at Urological Society of Australia and New Zealand, Darwin

Conference Papers | 2012

Ryan C; Morris M; Molina A; Piulats J; De Souza P; Li J; Kheoh T; de Bono J; Larson S; Griffin T; Matheny S; Naini V, 2012, 'Association of Radiographic Progression-Free Survival (Rpfs) adapted from Prostate Cancer Working Group 2 (Pcwg2) Consensus Criteria (Apcwg2) with Overall Survival (Os) in Patients (Pts) with Metastatic Castration-Resistant Prostate Cancer (Mcrpc): Results from Cou-Aa-302', in Annals of Oncology, Oxford Univ Press, Oxford, England, pp. 23 294-295; 9 SEP 2012, presented at ESMO Congress Vienna, Vienna, AUSTRIA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309409001375&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2012

Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; Kheoh TS; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate (AA) in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 01 June 2012 - 05 June 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318026200024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2012

Ryan CJ; Smith MR; De Bono JS; Molina A; Logothetis C; De Souza PL; Fizazi K; Mainwaring PN; Piulats Rodriguez JM; Ng S; Carles J; Mulders P; San Kheoh T; Griffin TW; Small EJ; Scher HI; Rathkopf DE, 2012, 'Interim analysis (IA) results of COU-AA-302, a randomized, phase III study of abiraterone acetate in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 01 June 2012 - 06 June 2012, http://dx.doi.org/10.1200/jco.2012.30.18_suppl.lba4518

Conference Papers | 2011

Kim MH; Li M; Mather-hillon J; Melbourne W; Tran K; Daniels BS; De Souza PL; Mallesara G; Murrell DF, 2011, 'Increased expression of EGFR in squamous cell carcinoma in recessive dystrophic epidermolysis bullosa and response to Cetuximab', in Australasian Journal of Dermatology, New South Wales : Wiley-Blackwell, Australia, pp. 32 - 32, presented at Abstracts of the Australasian College of Dermatologists 44th Annual Scientific Meeting, Perth Western Australia, 15 May 2011 - 18 May 2011, http://dx.doi.org/10.1111/j.1440-0960.2011.00757.x

Conference Papers | 2010

Paz-Ares L; Balint B; de Boer R; van Meerbeeck JP; Wierzbicki R; Desouza PL; Galimi F; Haddad V; Hei Y; Ramlau R, 2010, 'A RANDOMIZED, PHASE 2 STUDY OF PACLITAXEL (P) AND CARBOPLATIN (C) +/- CONATUMUMAB (CON) FOR FIRST-LINE TREATMENT OF NON-SMALL CELL LUNG CANCER (NSCLC)', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, ITALY, Milan, pp. 137 - 137, presented at 35th European-Society-for-Medical-Oncology (ESMO) Congress, ITALY, Milan, 08 October 2010 - 12 October 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283115900427&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2010

Webber K; Goldstein D; Bennett BK; Boyle F; De Souza PL; Wilken N; Friedlander M; Lloyd AR, 2010, 'Fatigue after adjuvant therapy for breast cancer influences health care utilisation and perceived needs', in Grunberg SM (ed.), Journal of Clinical Oncology, American Society of Clinical Oncology, Virginia USA, pp. 647s, presented at ., -

Conference Papers | 2010

Webber K; Goldstein D; Bennett BK; Boyle F; De Souza PL; Wilken N; Friedlander M; Lloyd AR, 2010, 'Late fatigue after adjuvant therapy for early breast cancer is largely unrelated to cancer or its treatment: 5 year follow-up of a prospective cohort study', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia Pty Ltd, Australia, pp. 53 - 60, presented at ., -

Conference Papers | 2009

Dutcher J; De Souza PL; McDermott D; Figlin R; Berkenblit A; Thiele A; Krygowski M; Strahs A; Feingold J; Hudes G, 2009, 'Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies', in Medical Oncology, Humana Press Inc, Totowa, NJ, USA, presented at Medical Oncology

Conference Papers | 2009

Metharom E; Galettis P; Manners S; Jelinek M; De Souza PL; Links MJ, 2009, 'Cytidine Deaminase c.79A > C Polymorphism Affected Optimal Dose Delivery of Gemcitabine', in Drug Metabolism Reviews, Marcel Dekker Inc, New York, NY, USA, pp. 231 - 232, presented at Drug Metabolism Reviews

Conference Papers | 2009

Webber K; Fontela A; Bonner N; Bell J; Bucci J; Lewis CR; De Souza PL; Graham PH; Links MJ, 2009, 'CRP predicts tolerance of treatment and overall survival with weekly carboplatin-paclitaxel and concomitant irradiation for locally advanced non-small cell lung cancer', in Journal of Thoracic Oncology, Lippincott Williams & Wilkins, USA, pp. S864 - S865, presented at 13th World Conference on Lung Cancer, San Francisco, USA, 31 July 2009 - 04 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000269496002560&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2008

Bennett BK; Goldstein D; Friedlander ML; Boyle F; De Souza PL; Wilken N; Hickie IB; Scott E; Lloyd AR, 2008, 'A prospective cohort study of fatigue after adjuvant therapy for breast cancer', in Psycho - Oncology, John Wiley & Sons Ltd, Chichester, W Sussex, England, pp. S36 - S37, presented at Psycho-Oncology 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000257874200071&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2008

Venugopal S; Martin L; Mangos G; Freiman J; Cheung K; Farnsworth AE; De Souza PL; Murrell DF, 2008, 'A study of rare presentations of metastatic melanoma', in Australasian Journal of Dermatology, New South Wales : Wiley-Blackwell, Australia, pp. A75 - A76, presented at Australasian Dermatopathology Society, 29th Annual Conference, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259822500004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2007

Chin MTM; Links MJ; Szwajcer ; De Souza PL, 2007, 'Lessons learnt in evaluating the target of drug action in a phase 1 trial of oral albendazole –a benzimidazole carbamate anti-helminthic- in patients with cancer refractory to conventional treatments.', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia, Australia, pp. A79 - A79, presented at Clinical Oncological Society of Australia (COSA) Annual Scientific Meeting 2007, Adelaide, Australia, http://www3.interscience.wiley.com/cgi-bin/fulltext/118500669/PDFSTART

Conference Papers | 2007

Hutson TE; Davis ID; Machiels JP; de Souza PL; Hong BF; Rottey S; Baker KL; Crofts T; Pandite L; Figlin R, 2007, 'Pazopanib (GW786034) is active in metastatic renal cell carcinoma (RCC): Interim results of a phase II randomized discontinuation trial (RDT)', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000455043701159&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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Professor Paul De Souza