Dr Richard Mitchell

Conjoint Senior Lecturer

B.Sc (Mol Biol), MBBS, FRACP

Medicine & Health
School of Clinical Medicine

Dr Mitchell completed his medical training at the University of Queensland, and undertook paediatric training at Sydney Children’s Hospital. He specialised in paediatric haematology/oncology, which included two clinical fellowships in paediatric bone marrow transplantation at the University of Minnesota, MN USA, and Memorial Sloan Kettering Cancer Centre, NY USA. Dr Mitchell is currently employed as a Paediatric Haematologist/Oncologist at the Kids Cancer Centre, Sydney Children’s Hospital. He is Deputy Director of the Blood and Marrow Transplantation Program at the Kids Cancer Centre, and a Conjoint Lecturer at the University of New South Wales. Dr Mitchell is the current chair of the ANZCHOG Bone Marrow Transplantation subgroup, the Australasian representative on the Children’s Oncology Group Cellular Therapy Steering Committee, and a member of the Australian Children’s Cancer Trials board. Dr Mitchell’s research interests include high risk leukaemia and non malignant transplantation, and he currently leads a national trial in the use of TCR α+β+/CD19+ cell depletion in paediatric patients undergoing bone marrow transplantation.

Phone
02 9382 1690
  • Journal articles | 2023
    Colgan JN; Fuentes-Bolanos NA; Barbaric D; Dalla-Pozza L; Mitchell R; Samarasinghe S; Schrappe M; Tucker KM; Schmiegelow K; Trahair TN, 2023, 'Scylla and Charybdis: Unpalatable choices in managing hypodiploid acute lymphoblastic leukemia', EJC Paediatric Oncology, 2, http://dx.doi.org/10.1016/j.ejcped.2023.100133
    Journal articles | 2023
    Selvanathan A; Forwood C; Russell J; Batten K; Thompson S; Palmer EE; Macintosh R; Nightingale S; Mitchell R; Alvaro F; Dudding‐Byth T; Lunke S; Christodoulou J; Stark Z; White F; Jones SA; Bhattacharya K, 2023, 'Rapid whole‐genome sequencing leading to specific treatment for two infants with haemophagocytic lymphohistiocytosis due to Wolman disease', Pediatric Blood and Cancer, http://dx.doi.org/10.1002/pbc.30394
    Journal articles | 2022
    Lawson R; Staatz CE; Fraser CJ; Ramachandran S; Teague L; Mitchell R; O'Brien T; Hennig S, 2022, 'Population pharmacokinetic model for once-daily intravenous busulfan in pediatric subjects describing time-associated clearance', CPT: Pharmacometrics and Systems Pharmacology, 11, pp. 1002 - 1017, http://dx.doi.org/10.1002/psp4.12809
    Journal articles | 2021
    Sutton R; Pozza LD; Khaw SL; Fraser C; Revesz T; Chamberlain J; Mitchell R; Trahair TN; Bateman CM; Venn NC; Law T; Ong E; Heatley SL; McClure BJ; Meyer C; Marschalek R; Henderson MJ; Cross S; White DL; Kotecha RS, 2021, 'Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab', Pediatric Blood and Cancer, 68, http://dx.doi.org/10.1002/pbc.28922
    Journal articles | 2020
    Chapman LR; Molloy L; Wright F; Oswald C; Adnum K; O'Brien TA; Mitchell R, 2020, 'Implementation of situational awareness in the pediatric oncology setting. Does a ‘huddle’ work and is it sustainable?', Journal of Pediatric Nursing, 50, pp. 75 - 80, http://dx.doi.org/10.1016/j.pedn.2019.10.016
    Journal articles | 2020
    Chapman LRM; Smith B; McCleary K; Mitchell R; O'Brien TA, 2020, 'Creating a CAR-T Cell Presentation Tool for the Emergency Room', BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 26, pp. S381 - S382, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000516887900600&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2020
    Chinnabhandar V; Tran S; Sutton R; Shaw PJ; Mechinaud F; Cole C; Tapp H; Teague L; Fraser C; O'Brien TA; Mitchell R, 2020, 'Addition of Thiotepa to Total Body Irradiation and Cyclophosphamide Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia', Biology of Blood and Marrow Transplantation, 26, pp. 2068 - 2074, http://dx.doi.org/10.1016/j.bbmt.2020.07.028
    Journal articles | 2020
    Grant A; Chapman LRM; Mitchell R; O’Brien TA, 2020, 'Engraftment syndrome following hematopoietic stem cell transplant: A review of the literature', Clinical Transplantation, 34, http://dx.doi.org/10.1111/ctr.13875
    Journal articles | 2020
    Klinken EM; Gray PE; Pillay B; Worley L; Edwards ESJ; Payne K; Bennetts B; Hung D; Wood BA; Chan JJ; Marshall GM; Mitchell R; Uzel G; Ma CS; Tangye SG; McLean-Tooke A, 2020, 'Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype', Journal of Clinical Immunology, 40, pp. 299 - 309, http://dx.doi.org/10.1007/s10875-019-00732-2
    Journal articles | 2020
    Richards S; Gennery AR; Davies EG; Wong M; Shaw PJ; Peake J; Fraser C; Gray P; Brothers S; Sinclair J; Prestidge T; Preece K; Quinn P; Ramachandran S; Loh R; McLean-Tooke A; Mitchell R; Cole T, 2020, 'Diagnosis and management of severe combined immunodeficiency in Australia and New Zealand', Journal of Paediatrics and Child Health, 56, pp. 1508 - 1513, http://dx.doi.org/10.1111/jpc.15158
    Journal articles | 2019
    Al Yazidi LS; Mitchell R; Palasanthiran P; O’Brien TA; McMullan B, 2019, 'Management and prevention of cytomegalovirus infection in paediatric hematopoietic stem cell transplant (HSCT) recipients: A binational survey', Pediatric Transplantation, 23, http://dx.doi.org/10.1111/petr.13458
    Journal articles | 2019
    Brettig T; Smart J; Choo S; Mechinaud F; Mitchell R; Raj TS; Cole T, 2019, 'Use of TCR α+β+/CD19+–Depleted Haploidentical Hematopoietic Stem Cell Transplant Is a Viable Option in Patients With Primary Immune Deficiency Without Matched Sibling Donor', Journal of Clinical Immunology, 39, pp. 505 - 511, http://dx.doi.org/10.1007/s10875-019-00648-x
    Journal articles | 2019
    Gerstl B; Sullivan E; Koch J; Wand H; Ives A; Mitchell R; Hamad N; Anazodo A, 2019, 'Reproductive outcomes following a stem cell transplant for a haematological malignancy in female cancer survivors: a systematic review and meta-analysis', Supportive Care in Cancer, 27, pp. 4451 - 4460, http://dx.doi.org/10.1007/s00520-019-05020-8
    Journal articles | 2019
    Gray PE; Shadur B; Russell S; Mitchell R; Gallagher K; Thia K; Palasanthiran P; Voskoboinik I, 2019, 'Neonatal cytomegalovirus palatal ulceration and bocavirus pneumonitis associated with a defect of lymphocyte cytotoxicity caused by mutations in UNC13D', Journal of the Pediatric Infectious Diseases Society, 8, pp. 73 - 76, http://dx.doi.org/10.1093/jpids/pix112
    Journal articles | 2019
    Keating AK; Langenhorst J; Wagner JE; Page KM; Veys P; Wynn RF; Stefanski H; Elfeky R; Giller R; Mitchell R; Milano F; O’Brien TA; Dahlberg A; Delaney C; Kurtzberg J; Verneris MR; Boelens JJ, 2019, 'The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia', Blood Advances, 3, pp. 1118 - 1128, http://dx.doi.org/10.1182/bloodadvances.2018025908
    Journal articles | 2019
    Mitchell R; Cole T; Shaw PJ; Mechinaud F; O'Brien T; Fraser C, 2019, 'TCR α+β+/CD19+ cell–depleted hematopoietic stem cell transplantation for pediatric patients', Pediatric Transplantation, 23, http://dx.doi.org/10.1111/petr.13517
    Journal articles | 2019
    Mitchell R, 2019, 'Hematopoietic Stem Cell Transplantation Beyond Severe Combined Immunodeficiency: Seeking a Cure for Primary Immunodeficiency', Journal of Allergy and Clinical Immunology: In Practice, 7, pp. 776 - 785, http://dx.doi.org/10.1016/j.jaip.2018.12.011
    Journal articles | 2019
    Pillay BA; Avery DT; Smart JM; Cole T; Choo S; Chan D; Gray PE; Frith K; Mitchell R; Phan TG; Wong M; Campbell DE; Hsu P; Ziegler JB; Peake J; Alvaro F; Picard C; Bustamante J; Neven B; Cant AJ; Uzel G; Arkwright PD; Casanova JL; Su HC; Freeman AF; Shah N; Hickstein DD; Tangye SG; Ma CS, 2019, 'Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients', JCI Insight, 4, http://dx.doi.org/10.1172/jci.insight.127527
    Journal articles | 2019
    Robertson EG; Wakefield CE; Cohn RJ; Battisti RA; Donoghoe MW; Ziegler DS; Fardell JE; Mitchell R; O'Brien TA, 2019, 'Piloting a parent and patient decision aid to support clinical trial decision making in childhood cancer', Psycho-Oncology, 28, pp. 1520 - 1529, http://dx.doi.org/10.1002/pon.5109
    Journal articles | 2019
    Salem B; Mitchell R; DeFor TE; Tryon R; Wagner JE; MacMillan ML, 2019, 'Elevations in serum alpha fetoprotein levels in patients with Fanconi anaemia.', Br J Haematol, 184, pp. 1032 - 1035, http://dx.doi.org/10.1111/bjh.15223
    Journal articles | 2018
    Chapman LRM; Falato K; Oswald C; Mitchell R; O'Brien TA, 2018, 'How Clean are We? Impact of Education on Cleaning Outcomes in the Pediatric BMT Setting', Biology of Blood and Marrow Transplantation, 24, pp. S448 - S449, http://dx.doi.org/10.1016/j.bbmt.2017.12.723
    Journal articles | 2018
    Keating AK; Langenhorst J; Wagner JE; Page K; Veys P; Wynn RF; Stefanski H; Elfeky R; Giller R; Mitchell R; Milano F; O'Brien TA; Dahlberg A; Delaney C; Kurtzberg J; Verneris MR; Boelens J-J, 2018, 'The Influence of Stem Cell Source on Chronic-GvHD Free, Leukemia Free Transplant Survival in Pediatric Patients with Acute Myeloid Leukemia', Biology of Blood and Marrow Transplantation, 24, pp. S113 - S114, http://dx.doi.org/10.1016/j.bbmt.2017.12.029
    Journal articles | 2018
    Mitchell R; Cole T; Shaw PJ; Mechinaud F; O'Brien TA; Fraser C, 2018, 'TCR Α+ Β+/CD19+ Cell Depleted Haematopoietic Stem Cell Transplantation for Paediatric Patients', Biology of Blood and Marrow Transplantation, 24, pp. S435 - S435, http://dx.doi.org/10.1016/j.bbmt.2017.12.522
    Journal articles | 2018
    Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, 40, pp. 541 - 547, http://dx.doi.org/10.1097/MPH.0000000000001215
    Journal articles | 2018
    van Sambeek B; Flattery M; Mitchell R; De Abreu Lourenco R, 2018, 'Comparing the cost of preparing matched unrelated donor and TCR α+β+/CD19+ depleted donor material for pediatric hematopoietic stem cell transplants in Australia', Pediatric Transplantation, 22, http://dx.doi.org/10.1111/petr.13279
    Journal articles | 2017
    Gray PE; Shadur B; Russell S; Mitchell R; Buckley M; Gallagher K; Andrews I; Thia K; Trapani JA; Kirk EP; Voskoboinik I, 2017, 'Late-onset Non-HLH presentations of growth arrest, inflammatory arachnoiditis, and severe infectious mononucleosis, in siblings with hypomorphic defects in UNC13D', Frontiers in Immunology, 8, http://dx.doi.org/10.3389/fimmu.2017.00944
    Journal articles | 2017
    Mitchell R; Wagner JE; Brunstein C; Cao Q; McKenna DH; Verneris MR, 2017, 'Impact of Delayed Infusion Time in Umbilical Cord Blood Transplantation', Biology of Blood and Marrow Transplantation, 23, pp. 836 - 839, http://dx.doi.org/10.1016/j.bbmt.2017.02.010
    Journal articles | 2017
    Norman M; David C; Wainstein B; Ziegler JB; Cohn R; Mitchell R; O'Brien T; Russell S; Trahair T; Trickett A; Frith K; Gray P, 2017, 'Haematopoietic stem cell transplantation for primary immunodeficiency syndromes: A 5-year single-centre experience', Journal of Paediatrics and Child Health, 53, pp. 988 - 994, http://dx.doi.org/10.1111/jpc.13643
    Journal articles | 2015
    Mitchell R; Wagner JE; Brunstein CG; Cao Q; McKenna DH; Lund TC; Verneris MR, 2015, 'Impact of long-term cryopreservation on single umbilical cord blood transplantation outcomes.', Biol Blood Marrow Transplant, 21, pp. 50 - 54, http://dx.doi.org/10.1016/j.bbmt.2014.09.002
    Journal articles | 2014
    Mitchell R; Wagner JE; Hirsch B; DeFor TE; Zierhut H; MacMillan ML, 2014, 'Haematopoietic cell transplantation for acute leukaemia and advanced myelodysplastic syndrome in Fanconi Anaemia', British Journal of Haematology, http://dx.doi.org/10.1111/bjh.12634
    Journal articles | 2013
    Mitchell R; Defor T; Wagner JE; MacMillan ML, 2013, 'Hematopoietic Cell Transplantation for Acute Leukemia and Advanced Myelodysplastic Syndrome in Fanconi Anemia', Biology of Blood and Marrow Transplantation, 19, pp. S163 - S164, http://dx.doi.org/10.1016/j.bbmt.2012.11.130
    Journal articles | 2013
    Mitchell R; Nivison-Smith I; Anazodo A; Tiedemann K; Shaw P; Teague L; Fraser C; Carter T; Tapp H; Alvaro F; O'Brien TA, 2013, 'Outcomes of Hematopoietic Stem Cell Transplantation in Primary Immunodeficiency: A Report from the Australian and New Zealand Children's Haematology Oncology Group and the Australasian Bone Marrow Transplant Recipient Registry', Biology of Blood and Marrow Transplantation, 19, pp. 338 - 343, http://dx.doi.org/10.1016/j.bbmt.2012.11.619
    Journal articles | 2013
    Mitchell R; Nivison-Smith I; Anazodo A; Tiedemann K; Shaw PJ; Teague L; Fraser CJ; Carter TL; Tapp H; Alvaro F; O'Brien TA, 2013, 'Outcomes of haematopoietic stem cell transplantation for inherited metabolic disorders: A report from the Australian and New Zealand Children's Haematology Oncology Group and the Australasian Bone Marrow Transplant Recipient Registry', Pediatric Transplantation, 17, pp. 582 - 588, http://dx.doi.org/10.1111/petr.12109
    Journal articles | 2012
    Mitchell R; Nivison-Smith J; Teidemann K; Mechinaud F; Shaw PJ; Teague L; Fraser C; Tapp H; Cole CH; Alvaro F; O'Brien TA, 2012, 'HAEMATOPOIETIC STEM CELL TRANSPLANTATION OUTCOMES IN PRIMARY IMMUNODEFICIENCY: A REPORT FROM ANZCHOG AND ABMTRR', BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 18, pp. S305 - S305, http://dx.doi.org/10.1016/j.bbmt.2011.12.259
    Journal articles | 2012
    Mitchell R; Smith N-I; Teidemann K; Mechinaud F; Shaw PJ; Teague L; Fraser C; Tapp H; Cole CH; Alvaro F; O'Brien TA, 2012, 'OUTCOMES OF HAEMATOPOIETIC STEM CELL TRANSPLANTATION FOR INHERITED METABOLIC DISORDERS: A REPORT FROM ANZCHOG AND ABMTRR', BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 18, pp. S301 - S301, http://dx.doi.org/10.1016/j.bbmt.2011.12.251
  • Conference Posters | 2022
    Cain LE; Araya M; Barbaric D; Chapman LRM; Manoharan N; Maurice LC; McCleary K; Mitchell R; O’Brien TA; Oswald C; Trahair TN; Trickett A; Nelson AS, 2022, 'Paediatric Experience of Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia', Vol. 28, pp. S174 - S175, http://dx.doi.org/10.1016/s2666-6367(22)00376-1
    Conference Posters | 2022
    Chapman LRM; Oswald C; Cain LE; Araya M; Coulits N; Maurice LC; McCleary K; Moses J; Mitchell R; OBrien TA; Wright FA; Trickett A; Nelson AS, 2022, 'Donor Selection in a Geographically Isolated Country during the COVID-19 Pandemic', Vol. 28, pp. S473 - S473, http://dx.doi.org/10.1016/s2666-6367(22)00780-1
    Conference Abstracts | 2019
    Robertson E; Wakefield C; Cohn R; Robert B; Donoghoe M; Ziegler D; Fardell J; Mitchell R; O'Brien T, 2019, 'Delta: A Parent and Patient Decision Aid to Support Clinical Trial Decision-Making in Childhood Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S118 - S118, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458001090&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Chinnabhandar V; Tran S; Sutton R; Shaw PJ; Mechinaud F; Cole C; Tapp H; Teague L; Fraser C; O'Brien TA; Mitchell R, 2018, 'Use of Thiotepa in Haematopoietic Stem Cell Transplantation for Paediatric Acute Lymphoblastic Leukaemia: An Australian and New Zealand Children's Haematology/Oncology Group Study', in Biology of Blood and Marrow Transplantation, Elsevier BV, Vol. 24, pp. S310 - S310, http://dx.doi.org/10.1016/j.bbmt.2017.12.357
    Conference Abstracts | 2018
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo A; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien TA, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective.', Hong Kong, presented at International Psycho-Oncology Society, Hong Kong, 31 October 2018 - 02 November 2018
    Conference Papers | 2018
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo AC; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien T, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster)', in Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster), Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, presented at Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, 14 June 2018 - 16 June 2018
    Conference Abstracts | 2016
    Robertson E; Fardell J; O'Brien T; Cohn R; Mitchell R; Drew D; Ziegler D; Marshall G; Wakefield C, 2016, 'Treatment Decision Making for Young People with Cancer and Their Parents', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S232 - S232, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384818801393&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1