Finch A; Sarramegna V; Graham RM, 2005, 'Ligand binding, activation and agonist trafficking', in Perez DM(ed.), The Adrenergic Receptors in the 21st Century, edn. Original, Humana Press, New Jersey, NJ, pp. 25 - 86
Willems EW; Husain A; Graham RM, 2004, 'Molecular Targets of Antihypertensive Drug Therapy', in Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease, pp. 539 - 565, http://dx.doi.org/10.1016/B978-0-7216-9428-3.50035-4
Book Chapters | 1995
Graham RM; Riek RP; Iismaa S; Chen S, 1995, 'Adrenergic and dopamine receptors', in Molecular Nephrology, edn. Original, Marcel Dekker, New York, pp. 143 - 155
Journal articles | 2023
Adlam D; Berrandou TE; Georges A; Nelson CP; Giannoulatou E; Henry J; Ma L; Blencowe M; Turley TN; Yang ML; Chopade S; Finan C; Braund PS; Sadeg-Sayoud I; Iismaa SE; Kosel ML; Zhou X; Hamby SE; Cheng J; Liu L; Tarr I; Muller DWM; d’Escamard V; King A; Brunham LR; Baranowska-Clarke AA; Debette S; Amouyel P; Olin JW; Patil S; Hesselson SE; Junday K; Kanoni S; Aragam KG; Butterworth AS; Bakker MK; Ruigrok YM; Tweet MS; Gulati R; Combaret N; Kadian-Dodov D; Kalman JM; Fatkin D; Hingorani AD; Saw J; Webb TR; Hayes SN; Yang X; Ganesh SK; Olson TM; Kovacic JC; Graham RM; Samani NJ; Bouatia-Naji N, 2023, 'Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation', Nature Genetics, 55, pp. 964 - 972, http://dx.doi.org/10.1038/s41588-023-01410-1
Journal articles | 2023
Baker JG; Balaji P; Bond RA; Bylund DB; Eikenburg DC; Graham RM; Hieble JP; Hills R; Michel MC; Minneman KP; Parra S; Perez D; Summers R, 2023, 'Adrenoceptors in GtoPdb v.2023.1', IUPHAR/BPS Guide to Pharmacology CITE, 2023, http://dx.doi.org/10.2218/gtopdb/f4/2023.1
Journal articles | 2023
Bax M; Junday K; Tarr I; Hesselson S; McGrath-Cadell L; Iismaa S; Giannoulatou E; Graham R, 2023, 'Proteomic Analysis Reveals TGFB Pathway Perturbation in Spontaneous Coronary Artery Dissection (SCAD) Patient iPSC Derived Endothelial Cells', Heart, Lung and Circulation, 32, pp. S416 - S416, http://dx.doi.org/10.1016/j.hlc.2023.06.585
Journal articles | 2023
Dang Q; Murphy B; Graham R; Puri A; Ford S; Marschner S; Chong J; Zaman S, 2023, 'Australian Patients’ Perspective of Quality of Hospital Care Following Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 32, pp. S270 - S270, http://dx.doi.org/10.1016/j.hlc.2023.06.347
Journal articles | 2023
McGrath-Cadell L; Hesselson S; Thompson J; Iismaa S; Tarr I I; Muller D; Kovacic J; Graham R; Giannoulatou E, 2023, 'COL3A1 Mutations in Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 32, pp. S126 - S126, http://dx.doi.org/10.1016/j.hlc.2023.06.757
Journal articles | 2023
Murphy BM; Rogerson MC; Hesselson S; Iismaa SE; Hoover V; Le Grande M; Graham RM; Jackson AC, 2023, 'Prevalence of Anxiety, Depression, and Distress in SCAD and Non-SCAD AMI Patients: A Comparative Study', Journal of cardiopulmonary rehabilitation and prevention, 43, pp. 338 - 345, http://dx.doi.org/10.1097/HCR.0000000000000782
Journal articles | 2023
Neavin DR; Steinmann AM; Farbehi N; Chiu HS; Daniszewski MS; Arora H; Bermudez Y; Moutinho C; Chan CL; Bax M; Tyebally M; Gnanasambandapillai V; Lam CE; Nguyen U; Hernández D; Lidgerwood GE; Graham RM; Hewitt AW; Pébay A; Palpant NJ; Powell JE, 2023, 'A village in a dish model system for population-scale hiPSC studies', Nature Communications, 14, pp. 3240, http://dx.doi.org/10.1038/s41467-023-38704-1
Journal articles | 2023
Pouliopoulos J; Anthony C; Imran M; Kessler C; Moffat K; Stehning C; Puntman V; Prasad S; Graham R; McCrohon J; Holloway C; Muthiah K; Keogh A; Hayward C; Jabbour A, 2023, 'Spatial Assessment and Utility of Left Ventricular Strain by Magnetic Resonance Feature Tracking in Patients after Orthotopic Heart Transplantation for Diagnosis of Rejection', Heart, Lung and Circulation, 32, pp. S256 - S256, http://dx.doi.org/10.1016/j.hlc.2023.06.315
Journal articles | 2023
Yiu TW; Holman SR; Kaidonis X; Graham RM; Iismaa SE, 2023, 'Transglutaminase 2 Facilitates Murine Wound Healing in a Strain-Dependent Manner', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms241411475
Journal articles | 2022
Anthony C; Imran M; Pouliopoulos J; Emmanuel S; Iliff J; Liu Z; Moffat K; Ru Qiu M; McLean CA; Stehning C; Puntmann V; Vassiliou V; Ismail TF; Gulati A; Prasad S; Graham RM; McCrohon J; Holloway C; Kotlyar E; Muthiah K; Keogh AM; Hayward CS; MacDonald PS; Jabbour A, 2022, 'Cardiovascular Magnetic Resonance for Rejection Surveillance After Cardiac Transplantation', Circulation, 145, pp. 1811 - 1824, http://dx.doi.org/10.1161/CIRCULATIONAHA.121.057006
Journal articles | 2022
Bax M; Junday K; Iismaa S; Hesselson S; Tarr I; McGrath-Cadell L; Dunwoodie S; Giannoulatou E; Graham R, 2022, 'Induced Pluripotent Stem Cell-Derived Models of Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 31, pp. S87 - S87, http://dx.doi.org/10.1016/j.hlc.2022.06.097
Journal articles | 2022
Bax M; Romanov V; Junday K; Giannoulatou E; Martinac B; Kovacic JC; Liu R; Iismaa SE; Graham RM, 2022, 'Arterial dissections: Common features and new perspectives', Frontiers in Cardiovascular Medicine, 9, http://dx.doi.org/10.3389/fcvm.2022.1055862
Journal articles | 2022
Bogush N; Tan L; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A, 2022, 'Remuscularization with triiodothyronine and β1-blocker therapy reverses post-ischemic left ventricular dysfunction and adverse remodeling', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-12723-2
Kashyap V; Gharleghi R; Li DD; McGrath-Cadell L; Graham RM; Ellis C; Webster M; Beier S, 2022, 'Accuracy of vascular tortuosity measures using computational modelling', Scientific Reports, 12, pp. 865, http://dx.doi.org/10.1038/s41598-022-04796-w
Journal articles | 2022
Kim SK; Wing-Lun E; Chandrasekhar J; Puri A; Burgess S; Ford TJ; Kovacic J; Graham RM; Psaltis PJ; Zaman S, 2022, 'The Australian New Zealand Spontaneous Coronary Artery Dissection (ANZ-SCAD) Registry – A Multi-Centre Cohort Study: Protocol, Background and Significance', Heart Lung and Circulation, 31, pp. 1612 - 1618, http://dx.doi.org/10.1016/j.hlc.2022.08.018
Journal articles | 2022
Mouat MA; Wilkins BP; Ding E; Govindaraju H; Coleman JLJ; Graham RM; Turner N; Smith NJ, 2022, 'Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1', Cells, 11, http://dx.doi.org/10.3390/cells11111814
Journal articles | 2022
Murphy BM; Rogerson MC; Hesselson S; Iismaa SE; Graham RM; Jackson AC, 2022, 'Psychosocial impacts of spontaneous coronary artery dissection: A qualitative study', PLoS ONE, 17, pp. e0273978, http://dx.doi.org/10.1371/journal.pone.0273978
Journal articles | 2022
Nicks AM; Holman SR; Chan AY; Tsang M; Young PE; Humphreys DT; Naqvi N; Husain A; Li M; Smith NJ; Iismaa SE; Graham RM, 2022, 'Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts', Journal of Molecular and Cellular Cardiology, 170, pp. 47 - 59, http://dx.doi.org/10.1016/j.yjmcc.2022.05.012
Journal articles | 2022
Tarr I; Hesselson S; Iismaa SE; Rath E; Monger S; Troup M; Mishra K; Wong CMY; Hsu PC; Junday K; Humphreys DT; Adlam D; Webb TR; Baranowska-Clarke AA; Hamby SE; Carss KJ; Samani NJ; Bax M; McGrath-Cadell L; Kovacic JC; Dunwoodie SL; Fatkin D; Muller DWM; Graham RM; Giannoulatou E, 2022, 'Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing', Circulation: Genomic and Precision Medicine, 15, pp. 267 - 277, http://dx.doi.org/10.1161/CIRCGEN.121.003527
Journal articles | 2022
Wu J; Nicks AM; Skowno JJ; Feneley MP; Graham RM; Iismaa SE, 2022, 'Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery', Journal of Visualized Experiments, 2022, http://dx.doi.org/10.3791/64004
Journal articles | 2022
Yu ZY; Gong H; Kesteven S; Guo Y; Wu J; Li JV; Cheng D; Zhou Z; Iismaa SE; Kaidonis X; Graham RM; Cox CD; Feneley MP; Martinac B, 2022, 'Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice', Nature Cardiovascular Research, 1, pp. 577 - 591, http://dx.doi.org/10.1038/s44161-022-00082-0
Journal articles | 2021
Altosaar K; Balaji P; Bond RA; Bylund DB; Cotecchia S; Devost D; Doze VA; Eikenburg DC; Gora S; Goupil E; Graham RM; Hébert T; Hieble JP; Hills R; Kan S; Machkalyan G; Michel MC; Minneman KP; Parra S; Perez D; Sleno R; Summers R; Zylbergold P, 2021, 'Adrenoceptors in GtoPdb v.2021.3', IUPHAR/BPS Guide to Pharmacology CITE, 2021, http://dx.doi.org/10.2218/gtopdb/f4/2021.3
Journal articles | 2021
Anthony C; Imran M; Pouliopoulos J; Emmanuel S; Iliff JW; Moffat KJ; Ross J; Graham RM; Kotlyar E; Muthiah K; Keogh AM; Hayward CS; Macdonald P; Jabbour A, 2021, 'Everolimus for the Prevention of Calcineurin-Inhibitor-Induced Left Ventricular Hypertrophy After Heart Transplantation (RADTAC Study)', JACC: Heart Failure, 9, pp. 301 - 313, http://dx.doi.org/10.1016/j.jchf.2021.01.007
Journal articles | 2021
Bax M; Junday K; Hesselson S; Iismaa S; Tarr I; McGrath-Cadell L; Dunwoodie S; Fatkin D; Kovacic J; Muller D; Giannoulatou E; Graham R, 2021, 'Modelling Spontaneous Coronary Artery Dissection With iPSC-Derived Vascular Cells', Heart, Lung and Circulation, 30, pp. S131 - S131, http://dx.doi.org/10.1016/j.hlc.2021.06.089
Journal articles | 2021
Guo Y; Yu ZY; Wu J; Gong H; Kesteven S; Iismaa SE; Chan AY; Holman S; Pinto S; Pironet A; Cox CD; Graham RM; Vennekens R; Feneley MP; Martinac B, 2021, 'The ca2+-activated cation channel trpm4 is a positive regulator of pressure overload-induced cardiac hypertrophy', eLife, 10, http://dx.doi.org/10.7554/eLife.66582
Journal articles | 2021
Iismaa SE; Hesselson S; McGrath-Cadell L; Muller DW; Fatkin D; Giannoulatou E; Kovacic J; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women', Heart Lung and Circulation, 30, pp. 27 - 35, http://dx.doi.org/10.1016/j.hlc.2020.05.110
Journal articles | 2021
Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Vatner S; Feneley M; Graham RM, 2021, 'Adaptation to exercise-induced stress is not dependent on cardiomyocyte α1A-adrenergic receptors', Journal of Molecular and Cellular Cardiology, 155, pp. 78 - 87, http://dx.doi.org/10.1016/j.yjmcc.2021.02.010
Journal articles | 2021
McGrath-Cadell L; Hesselson S; Tarr I; Iismaa SE; Bax M; Junday K; Dunwoodie SE; Fatkin D; Kovacic J; Muller DWM; Giannoulatou E; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection (SCAD) and a family history of aortic artery dissection, a case series', European Heart Journal, 42, http://dx.doi.org/10.1093/eurheartj/ehab724.2787
Journal articles | 2021
McGrath-Cadell L; Iismaa SE; Hesselson S; Muller DW; Fatkin D; Giannoulatou E; Kovacic JC; Graham RM, 2021, 'Recent Updates on Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia', International Journal of Integrative Cardiology, 3, http://dx.doi.org/10.47275/2690-862x-121
Journal articles | 2021
Mouat MA; Coleman JLJ; Wu J; dos Remedios CG; Feneley MP; Graham RM; Smith NJ, 2021, 'Involvement of GPR37L1 in murine blood pressure regulation and human cardiac disease pathophysiology', American Journal of Physiology - Heart and Circulatory Physiology, 321, pp. H807 - H817, http://dx.doi.org/10.1152/ajpheart.00198.2021
Journal articles | 2021
Mouat MA; Jackson KL; Coleman JLJ; Paterson MR; Graham RM; Head GA; Smith NJ, 2021, 'Deletion of Orphan G Protein-Coupled Receptor GPR37L1 in Mice Alters Cardiovascular Homeostasis in a Sex-Specific Manner', Frontiers in Pharmacology, 11, http://dx.doi.org/10.3389/fphar.2020.600266
Journal articles | 2021
Naqvi N; Iismaa SE; Graham RM; Husain A, 2021, 'Mechanism-Based Cardiac Regeneration Strategies in Mammals', Frontiers in Cell and Developmental Biology, 9, pp. 747842, http://dx.doi.org/10.3389/fcell.2021.747842
Journal articles | 2021
Ngo T; Ilatovskiy AV; Stewart AG; Coleman JLJ; McRobb FM; Riek RP; Graham RM; Abagyan R; Kufareva I; Smith NJ, 2021, 'Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors (Nature Chemical Biology, (2017), 13, 2, (235-242), 10.1038/nchembio.2266)', Nature Chemical Biology, 17, pp. 501, http://dx.doi.org/10.1038/s41589-021-00746-1
Journal articles | 2021
Nicks AM; Holman SR; Chan AY; Pang C-HJ; Tsang M; Naqvi N; Husain A; Li M; Humphreys DT; Smith NJ; Iismaa SE; Graham RM, 2021, 'Abstract 11948: A Standardized Method to Isolate and Purify Cardiomyocytes from Individual Mouse Hearts Irrespective of Postnatal Age', Circulation, 144, pp. a11948 - a11948, http://dx.doi.org/10.1161/circ.144.suppl_1.11948
Journal articles | 2021
Tan L; Bogush N; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A, 2021, 'Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts', Theranostics, 11, pp. 4790 - 4808, http://dx.doi.org/10.7150/thno.57456
Journal articles | 2021
Vatner SF; Zhang J; Vyzas C; Mishra K; Graham RM; Vatner DE, 2021, 'Vascular Stiffness in Aging and Disease', Frontiers in Physiology, 12, pp. 762437, http://dx.doi.org/10.3389/fphys.2021.762437
Journal articles | 2021
Yu ZY; Gong H; Wu J; Dai Y; Kesteven SH; Fatkin D; Martinac B; Graham RM; Feneley MP, 2021, 'Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload', Frontiers in Cell and Developmental Biology, 9, pp. 639509, http://dx.doi.org/10.3389/fcell.2021.639509
Journal articles | 2021
2021, 'Abstract 11949: Disease-Specific and Comorbidity-Related Polygenic Risk in Spontaneous Coronary Artery Dissection', Circulation, 144, pp. a11949 - a11949, http://dx.doi.org/10.1161/circ.144.suppl_1.11949
Journal articles | 2020
Bogush N; Tan L; Naib H; Faizullabhoy E; Calvert JW; Iismaa SE; Gupta A; Ramchandran R; Martin DIK; Graham RM; Husain A; Naqvi N, 2020, 'DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling', Scientific Reports, 10, pp. 21918, http://dx.doi.org/10.1038/s41598-020-78825-x
Coleman J; Ngo T; Smythe R; Cleave A; Jones N; Graham R; Smith N, 2020, 'The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases', , http://dx.doi.org/10.1101/2020.06.27.174847
Journal articles | 2020
Coleman JLJ; Ngo T; Smythe RE; Cleave AJ; Jones NM; Graham RM; Smith NJ, 2020, 'The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-76384-9
Journal articles | 2020
Nicks AM; Kesteven SH; Li M; Wu J; Chan AY; Naqvi N; Husain A; Feneley MP; Smith NJ; Iismaa SE; Graham RM, 2020, 'Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes', Scientific Reports, 10, pp. 15318, http://dx.doi.org/10.1038/s41598-020-72273-3
Journal articles | 2020
Situ Y; Baric J; Han W; Law M; Fatkin D; Graham R, 2020, '055 Prevalence and Patient Awareness of Cardiovascular Risk Factors in a Community-Based Australian Cohort', Heart, Lung and Circulation, 29, pp. S62 - S62, http://dx.doi.org/10.1016/j.hlc.2020.09.062
Journal articles | 2020
Suzuki AS; Yagi R; Kimura MY; Iwamura C; Shinoda K; Onodera A; Hirahara K; Tumes DJ; Koyama-Nasu R; Iismaa SE; Graham RM; Motohashi S; Nakayama T, 2020, 'Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation', Frontiers in Immunology, 11, http://dx.doi.org/10.3389/fimmu.2020.01536
Journal articles | 2020
Tan L; Bogush N; Naqvi E; Calvert J; Graham R; Taylor R; Naqvi N; Husain A, 2020, 'Thyroid hormone (T3) plus dual-specificity phosphatase-5 siRNA therapy regenerates the myocardium lost as a result of doxorubicin cardiotoxicity', , http://dx.doi.org/10.21203/rs.3.rs-59095/v1
Journal articles | 2020
Thavapalachandran S; Grieve SM; Hume RD; Le TYL; Raguram K; Hudson JE; Pouliopoulos J; Figtree GA; Dye RP; Barry AM; Brown P; Lu J; Coffey S; Kesteven SH; Mills RJ; Rashid FN; Taran E; Kovoor P; Thomas L; Denniss AR; Kizana E; Asli NS; Xaymardan M; Feneley MP; Graham RM; Harvey RP; Chong JJH, 2020, 'Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction', Science Translational Medicine, 12, http://dx.doi.org/10.1126/scitranslmed.aay2140
Journal articles | 2019
Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Motreff P; Belle L; Dupouy P; Barnay P; Meneveau N; Gilard M; Rioufol G; Range G; Brunel P; Delarche N; Filippi E; Le Bivic L; Harbaoui B; Benamer H; Cayla G; Varenne O; Manzo-Silberman SP; Silvain J; Spaulding C; Caussin C; Gerbaud E; Valy Y; Koning R; Lhermusier T; Champin S; Salengro E; Fluttaz A; Zabalawi A; Cottin Y; Teiger E; Saint-Etienne C; Ducrocq G; Marliere S; Boiffard E; Aubry P; Georges JL; Bresson D; De Poli F; Karrillon G; Roule V; Bali L; Valla M; Gerbay A; Houpe D; Dubreuil O; Monnier A; Mayaud N; Manchuelle A; Commeau P; Bedossa M; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, 73, pp. 58 - 66, http://dx.doi.org/10.1016/j.jacc.2018.09.085
Journal articles | 2019
Alankarage D; Ip E; Szot JO; Munro J; Blue GM; Harrison K; Cuny H; Enriquez A; Troup M; Humphreys DT; Wilson M; Harvey RP; Sholler GF; Graham RM; Ho JWK; Kirk EP; Pachter N; Chapman G; Winlaw DS; Giannoulatou E; Dunwoodie SL, 2019, 'Identification of clinically actionable variants from genome sequencing of families with congenital heart disease', Genetics in Medicine, 21, pp. 1111 - 1120, http://dx.doi.org/10.1038/s41436-018-0296-x
Journal articles | 2019
Altosaar K; Balaji P; Bond RA; Bylund DB; Cotecchia S; Devost D; Doze VA; Eikenburg DC; Gora S; Goupil E; Graham RM; Hébert T; Hieble JP; Hills R; Kan S; Machkalyan G; Michel MC; Minneman KP; Parra S; Perez D; Sleno R; Summers R; Zylbergold P, 2019, 'Adrenoceptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database', IUPHAR/BPS Guide to Pharmacology CITE, 2019, http://dx.doi.org/10.2218/gtopdb/f4/2019.4
Journal articles | 2019
Chew HC; Iyer A; Connellan M; Scheuer S; Villanueva J; Gao L; Hicks M; Harkness M; Soto C; Dinale A; Nair P; Watson A; Granger E; Jansz P; Muthiah K; Jabbour A; Kotlyar E; Keogh A; Hayward C; Graham R; Spratt P; Macdonald P; Dhital K, 2019, 'Outcomes of Donation After Circulatory Death Heart Transplantation in Australia', Journal of the American College of Cardiology, 73, pp. 1447 - 1459, http://dx.doi.org/10.1016/j.jacc.2018.12.067
Journal articles | 2019
Coleman JLJ; Ngo T; Schmidt J; Mrad N; Liew CK; Jones NM; Graham RM; Smith NJ, 2019, 'Retraction: Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity (Science Signaling (2016) 9 (ra36) DOI: 10.1126/scisignal.aad1089)', Science Signaling, 12, http://dx.doi.org/10.1126/scisignal.aba2063
Journal articles | 2019
Figtree GA; Jennings G; Nicholls S; Graham RM, 2019, 'The Australian Cardiovascular Alliance–Towards an Integrated Whole-of-Nation Strategy to Address Our Major Health Burden', Heart Lung and Circulation, 28, pp. 198 - 203, http://dx.doi.org/10.1016/j.hlc.2018.12.002
Journal articles | 2019
Kaidonis X; Niu W; Chan AY; Kesteven S; Wu J; Iismaa SE; Feneley M; Graham RM, 2019, 'Abstract 579: Involvement of the Alpha 1A-Adrenergic Receptor in the Cardiac Adaptation to Physiological Stress', Circulation Research, 125, http://dx.doi.org/10.1161/res.125.suppl_1.579
Journal articles | 2019
McGrath-Cadell L; Hesselson S; Iismaa S; Mishra K; Wong C; Fatkin D; Dunwoodie S; Harvey R; Holloway C; Muller D; Giannoulatou E; Graham R, 2019, 'Familial Clustering of Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, 28, pp. S330 - S330, http://dx.doi.org/10.1016/j.hlc.2019.06.454
Journal articles | 2019
McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'P5540Familial clustering of spontaneous coronary artery dissection', European Heart Journal, 40, http://dx.doi.org/10.1093/eurheartj/ehz746.0486
Journal articles | 2019
Mishra K; Junday K; Wong CMY; Chan AY; Hesselson S; Muller DW; Iismaa SE; Mehta A; Graham RM, 2019, 'Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection', Stem Cell Research, 41, pp. 101584 - 101584, http://dx.doi.org/10.1016/j.scr.2019.101584
Journal articles | 2019
Serrano RL; Yu W; Graham RM; Liu- Bryan R; Terkeltaub R, 2019, 'A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia', PLoS ONE, 14, http://dx.doi.org/10.1371/journal.pone.0212235
Journal articles | 2019
Tan L; Bogush N; Naib H; Perry J; Calvert JW; Martin DIK; Graham RM; Naqvi N; Husain A, 2019, 'Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-53705-1
Journal articles | 2018
Coleman JLJ; Mouat MA; Wu J; Jancovski N; Bassi JK; Chan AY; Humphreys DT; Mrad N; Yu ZY; Ngo T; Iismaa S; Dos Remedios CG; Feneley MP; Allen AM; Graham RM; Smith NJ, 2018, 'Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control', Biology of Sex Differences, 9, http://dx.doi.org/10.1186/s13293-018-0173-y
Journal articles | 2018
Graham RM; McGrath-Cadell L; Muller DWM; Holloway CJ, 2018, 'The Mystery and Enigma of Spontaneous Coronary Artery Dissection', Heart Lung and Circulation, 27, pp. 401 - 405, http://dx.doi.org/10.1016/S1443-9506(18)30060-X
Iismaa SE; Li M; Kesteven S; Wu J; Chan AY; Holman SR; Calvert JW; Haq AU; Nicks AM; Naqvi N; Husain A; Feneley MP; Graham RM, 2018, 'Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-24525-6
Journal articles | 2018
Szot JO; Cuny H; Blue GM; Humphreys DT; Ip E; Harrison K; Sholler GF; Giannoulatou E; Leo P; Duncan EL; Sparrow DB; Ho JWK; Graham RM; Pachter N; Chapman G; Winlaw DS; Dunwoodie SL, 2018, 'A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data', Circulation. Genomic and precision medicine, 11, pp. e001978, http://dx.doi.org/10.1161/CIRCGEN.117.001978
Journal articles | 2018
Thavapalachandran S; Grieve S; Le L; Figtree G; Pouliopoulos J; Barry A; Brown P; Lu J; Raguram K; Kovoor P; Denniss R; Sindone A; Kizana E; Feneley M; Graham R; Harvey R; Chong J, 2018, 'Recombinant Human Platelet-Derived Growth Factor AB Improves Cardiac Function and Decreases Ventricular Arrhythmias by Modulating Scar and Angiogenesis After Myocardial Infarction', Heart, Lung and Circulation, 27, pp. S41 - S41, http://dx.doi.org/10.1016/j.hlc.2018.06.002
Journal articles | 2017
Asli N; Xaymardan M; Patrick R; Farbehi N; Cornwell J; Forte E; Waardenberg A; Janbandhu V; Kesteven S; Chandrakanthan V; Malinowska H; Reinhard H; Schofield P; Christ D; Ahmed I; Bouveret R; Srivastava S; Mishra R; Dhawan J; Chong JJH; Nordon R; Macdonald P; Graham R; Feneley M; Harvey R, 2017, 'PDGFRα signaling in cardiac fibroblasts modulates quiescence, metabolism and self-renewal, and promotes anatomical and functional repair', , http://dx.doi.org/10.1101/225979
Journal articles | 2017
Guers J; Yoon S; Zhang J; Zhao X; Vatner DE; Graham R; Vatner SF, 2017, 'A1A-ADRENERGIC RECEPTOR OVEREXPRESSION PROTECTS AGAINST THE DEVELOPMENT OF ARRHYTHMIAS FOLLOWING CORONARY ARTERY OCCLUSION', Journal of the American College of Cardiology, 69, pp. 465 - 465, http://dx.doi.org/10.1016/s0735-1097(17)33854-8
Journal articles | 2017
Ngo T; Ilatovskiy AV; Stewart AG; Coleman JLJ; McRobb FM; Riek RP; Graham RM; Abagyan R; Kufareva I; Smith NJ, 2017, 'Orphan receptor ligand discovery by pickpocketing pharmacological neighbors', Nature Chemical Biology, 13, pp. 235 - 242, http://dx.doi.org/10.1038/nchembio.2266
Journal articles | 2016
Coleman JLJ; Ngo T; Schmidt J; Mrad N; Liew CK; Jones NM; Graham RM; Smith NJ, 2016, 'Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity', Science Signaling, 9, http://dx.doi.org/10.1126/scisignal.aad1089
Journal articles | 2016
Constantine M; Liew CK; Lo V; MacMillan A; Cranfield CG; Sunde M; Whan R; Graham RM; Martinac B, 2016, 'Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer', Scientific Reports, 6, http://dx.doi.org/10.1038/srep19352
Journal articles | 2016
Graham RM, 2016, 'The Victor Chang cardiac research institute: Australia's premier organization addressing cardiovascular diseases at the cellular and molecular level', European Heart Journal, 37, pp. 2566 - 2567, http://dx.doi.org/10.1093/eurheartj/ehw317
Journal articles | 2016
Harvey RP; Wystub-Lis K; del Monte-Nieto G; Graham RM; Tzahor E, 2016, 'Cardiac Regeneration Therapies - Targeting Neuregulin 1 Signalling', Heart Lung and Circulation, 25, pp. 4 - 7, http://dx.doi.org/10.1016/j.hlc.2015.08.014
Journal articles | 2016
Iyer A; Chew HC; Gao L; Villanueva J; Hicks M; Doyle A; Kumarasinghe G; Jabbour A; Jansz PC; Feneley MP; Harvey RP; Graham RM; Dhital KK; Macdonald PS, 2016, 'Pathophysiological Trends during Withdrawal of Life Support: Implications for Organ Donation after Circulatory Death', Transplantation, 100, pp. 2621 - 2629, http://dx.doi.org/10.1097/TP.0000000000001396
Journal articles | 2016
Li M; Tejada T; Lambert JP; Nicholson CK; Yahiro E; Ambai VT; Ali SF; Bradley EW; Graham RM; Dell'Italia LJ; Calvert JW; Naqvi N, 2016, 'Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-γ.', Am J Cardiovasc Dis, 6, pp. 118 - 128, https://www.ncbi.nlm.nih.gov/pubmed/27679746
Journal articles | 2016
MacDiarmid JA; Langova V; Bailey D; Pattison ST; Pattison SL; Christensen N; Armstrong LR; Brahmbhatt VN; Smolarczyk K; Harrison MT; Costa M; Mugridge NB; Sedliarou I; Grimes NA; Kiss DL; Stillman B; Hann CL; Gallia GL; Graham RM; Brahmbhatt H, 2016, 'Targeted doxorubicin delivery to brain tumors via minicells: Proof of principle using dogs with spontaneously occurring tumors as a model', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0151832
Journal articles | 2016
McGrath-Cadell L; McKenzie P; Emmanuel S; Muller DWM; Graham RM; Holloway CJ, 2016, 'Outcomes of patients with spontaneous coronary artery dissection', OPEN HEART, 3, http://dx.doi.org/10.1136/openhrt-2016-000491
Journal articles | 2016
McNamara JW; Li A; Smith NJ; Lal S; Graham RM; Kooiker KB; van Dijk SJ; Remedios CGD; Harris SP; Cooke R, 2016, 'Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes', Journal of Molecular and Cellular Cardiology, 94, pp. 65 - 71, http://dx.doi.org/10.1016/j.yjmcc.2016.03.009
Journal articles | 2016
Ngo T; Kufareva I; Coleman JLJ; Graham RM; Abagyan R; Smith NJ, 2016, 'Identifying ligands at orphan GPCRs: current status using structure-based approaches', British Journal of Pharmacology, 173, pp. 2934 - 2951, http://dx.doi.org/10.1111/bph.13452
Journal articles | 2016
Shi H; O’Reilly VC; Moreau JLM; Bewes TR; Yam MX; Chapman BE; Grieve SM; Stocker R; Graham RM; Chapman G; Sparrow DB; Dunwoodie SL, 2016, 'Gestational stress induces the unfolded protein response, resulting in heart defects', Development (Cambridge), 143, pp. 2561 - 2572, http://dx.doi.org/10.1242/dev.136820
Journal articles | 2016
Soetanto R; Hynes CJ; Patel HR; Humphreys DT; Evers M; Duan G; Parker BJ; Archer SK; Clancy JL; Graham RM; Beilharz TH; Smith NJ; Preiss T, 2016, 'Role of miRNAs and alternative mRNA 3'-end cleavage and polyadenylation of their mRNA targets in cardiomyocyte hypertrophy', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 1859, pp. 744 - 756, http://dx.doi.org/10.1016/j.bbagrm.2016.03.010
Journal articles | 2016
Tay EMY; Graham RI; Day RO, 2016, 'Severe GHB withdrawal delirium managed with dexmedetomidine', Medical Journal of Australia, 205, pp. 251 - 252.e1, http://dx.doi.org/10.5694/MJA16.00269
Journal articles | 2016
Tejada T; Tan L; Torres RA; Calvert JW; Lambert JP; Zaidi M; Husain M; Berce MD; Naib H; Pejler G; Abrink M; Graham RM; Lefer DJ; Naqvi N; Husain A, 2016, 'IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction', Proceedings of the National Academy of Sciences of the United States of America, 113, pp. 6949 - 6954, http://dx.doi.org/10.1073/pnas.1603127113
Journal articles | 2015
Cannon L; Yu ZY; Marciniec T; Waardenberg AJ; Iismaa SE; Nikolova-Krstevski V; Neist E; Ohanian M; Qiu MR; Rainer S; Harvey RP; Feneley MP; Graham RM; Fatkin D, 2015, 'Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period', Journal of the American College of Cardiology, 65, pp. 560 - 569, http://dx.doi.org/10.1016/j.jacc.2014.10.069
Journal articles | 2015
Coleman JLJ; Brennan K; Ngo T; Balaji P; Graham RM; Smith NJ, 2015, 'Rapid knockout and reporter mouse line generation and breeding colony establishment using EUCOMM conditional-ready embryonic stem cells: A case study', Frontiers in Endocrinology, 6, http://dx.doi.org/10.3389/fendo.2015.00105
Journal articles | 2015
Dhital KK; Iyer A; Connellan M; Chew HC; Gao L; Doyle A; Hicks M; Kumarasinghe G; Soto C; Dinale A; Cartwright B; Nair P; Granger E; Jansz P; Jabbour A; Kotlyar E; Keogh A; Hayward C; Graham R; Spratt P; Macdonald P, 2015, 'Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: A case series', The Lancet, 385, pp. 2585 - 2591, http://dx.doi.org/10.1016/S0140-6736(15)60038-1
Journal articles | 2015
Iyer A; Gao L; Doyle A; Rao P; Cropper JR; Soto C; Dinale A; Kumarasinghe G; Jabbour A; Hicks M; Jansz PC; Feneley MP; Harvey RP; Graham RM; Dhital KK; MacDonald PS, 2015, 'Normothermic Ex Vivo Perfusion Provides Superior Organ Preservation and Enables Viability Assessment of Hearts From DCD Donors', American Journal of Transplantation, 15, pp. 371 - 380, http://dx.doi.org/10.1111/ajt.12994
Journal articles | 2015
Naqvi N; Singh R; Iismaa SE; Li M; Calvert JW; Martin DIK; Harvey RP; Graham RM; Husain A, 2015, 'Cardiomyocytes Replicate and their Numbers Increase in Young Hearts', Cell, 163, pp. 783 - 784, http://dx.doi.org/10.1016/j.cell.2015.10.038
Journal articles | 2015
Zhao X; Balaji P; Pachon R; Beniamen DM; Vatner DE; Graham RM; Vatner SF, 2015, 'Overexpression of Cardiomyocyte α1A-Adrenergic Receptors Attenuates Postinfarct Remodeling by Inducing Angiogenesis Through Heterocellular Signaling', Arteriosclerosis, Thrombosis, and Vascular Biology, 35, pp. 2451 - 2459, http://dx.doi.org/10.1161/ATVBAHA.115.305919
Journal articles | 2014
Harvey RP; Graham RM; Pu WT, 2014, 'Introduction to the Special Issue on Heart Regeneration and Rejuvenation', Stem Cell Research, 13, pp. 521 - 522, http://dx.doi.org/10.1016/j.scr.2014.10.003
Journal articles | 2014
Iyer A; Gao L; Doyle A; Rao P; Jayewardene D; Wan B; Kumarasinghe G; Jabbour A; Hicks M; Jansz PC; Feneley MP; Harvey RP; Graham RM; Dhital KK; Macdonald PS, 2014, 'Increasing the Tolerance of DCD Hearts to Warm Ischemia by Pharmacological Postconditioning', American Journal of Transplantation, 14, pp. 1744 - 1752, http://dx.doi.org/10.1111/ajt.12782
Journal articles | 2014
Li M; Iismaa SE; Naqvi N; Nicks A; Husain A; Graham RM, 2014, 'Thyroid hormone action in postnatal heart development', Stem Cell Research, 13, pp. 582 - 591, http://dx.doi.org/10.1016/j.scr.2014.07.001
Journal articles | 2014
Naqvi N; Li M; Calvert JW; Tejada T; Lambert JP; Wu J; Kesteven SH; Holman SR; Matsuda T; Lovelock JD; Howard WW; Iismaa SE; Chan AY; Crawford BH; Wagner MB; Martin DIK; Lefer DJ; Graham RM; Husain A, 2014, 'A proliferative burst during preadolescence establishes the final cardiomyocyte number', Cell, 157, pp. 795 - 807, http://dx.doi.org/10.1016/j.cell.2014.03.035
Journal articles | 2014
Navarini AA; Simpson MA; Weale M; Knight J; Carlavan I; Reiniche P; Burden DA; Layton A; Bataille V; Allen M; Pleass R; Pink A; Creamer D; English J; Munn S; Walton S; Willis C; Akhras V; Alexandroff A; Anstey A; Azad J; Aziz O; Baudry D; Burrows N; Butt A; Cartwright P; Chapman A; Clayton T; Cliff S; Cunliffe W; Cutler T; Daly B; Damian E; Darvay A; DeGiovanni C; Downs A; Duckworth M; Dwyer C; Ferguson A; Fleming C; Fox Z; Frazer-Andrews E; Gonzalez J; Goodfield M; Graham R; Grattan C; Green N; Hazelwood-Smith S; Hempel H; Hood S; Hughes B; Ladoyanni E; Lyon C; Mahmud A; Malik M; Meggitt S; Messenger A; Moosa Y; Ormerod A; Patel V; Rallan D; Robertson S; Ross J; Salvary I; Wachsmuth R; Wahie S; Williamson D; Déret S; Voegel JJ; Spector T; Smith CH; Trembath RC; Barker JN, 2014, 'Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris', Nature Communications, 5, http://dx.doi.org/10.1038/ncomms5020
Journal articles | 2014
Yu ZY; Tan JC; McMahon AC; Iismaa SE; Xiao H; Kesteven SH; Reichelt ME; Mohl MC; Smith NJ; Fatkin D; Allen D; Head SI; Graham RM; Feneley MP, 2014, 'RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0099024
Journal articles | 2014
Zhao X; Pachon R; Yan L; Lee G; Sui X; Beniamen D; Balaji P; Ho D; Vatner DE; Graham RM; Vatner SF, 2014, 'Abstract 18134: Cardiomyocyte Overexpression of the alpha1A-Adrenergic Receptor in the Rat Protects Post-Infarct Heart Failure through Angiogenesis and the MEK-ERK Pathway', Circulation, 130, http://dx.doi.org/10.1161/circ.130.suppl_2.18134
Journal articles | 2013
Chalmers J; Angus J; Graham R; Carmody J; Dampney R; Jennings G; Korner N, 2013, 'Paul Ivan Korner 1925-2012', HISTORICAL RECORDS OF AUSTRALIAN SCIENCE, 24, pp. 251 - 282, http://dx.doi.org/10.1071/HR13008
Journal articles | 2013
Costa MW; Guo G; Wolstein O; Vale M; Castro ML; Wang L; Otway R; Riek P; Cochrane N; Furtado M; Semsarian C; Weintraub RG; Yeoh T; Hayward C; Keogh A; Macdonald P; Feneley M; Graham RM; Seidman JG; Seidman CE; Rosenthal N; Fatkin D; Harvey RP, 2013, 'Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy', Circulation: Cardiovascular Genetics, 6, pp. 238 - 247, http://dx.doi.org/10.1161/CIRCGENETICS.113.000057
Journal articles | 2013
Yu Z; Tan J; McMahon A; Iismaa S; Xiao X; Kesteven S; Reichelt M; Mohl M; Dai Y; Sketchley A; Yang L; Gong H; Fatkin D; Allen D; Head S; Graham R; Feneley M, 2013, 'Studies of a Mouse Model of Cardiac α1A-Adrenergic Receptor Overexpression Provide Evidence For a Critical Role of RhoA/ROCK Signalling in Cardiac Contractility', Heart, Lung and Circulation, 22, pp. S59 - S59, http://dx.doi.org/10.1016/j.hlc.2013.05.143
Journal articles | 2012
Iismaa SE; Aplin M; Yiu T-W; Wu J; Du X-J; Graham RM, 2012, '877 TransglutaminAse 2 is cardioprotective following MyoCardal INFARCTION, but plays no role in cardiac hyPERtrophy', Journal of Hypertension, 30, pp. e256 - e256, http://dx.doi.org/10.1097/01.hjh.0000420443.49005.96
Journal articles | 2012
Mohl M; Xiao X-H; Balaji P; Issmaa S; Feneley M; Graham R, 2012, 'The
α
1A‐adrenergic receptor mediates cardiac hypertrophy through the G
α
q‐PI3K‐Rac1 signaling pathway', The FASEB Journal, 26, pp. 663.4 - 663.4, http://dx.doi.org/10.1096/fasebj.26.1_supplement.663.4
Zhao X; Park J; Ho D; Gao S; Yan L; Ge H; Iismaa S; Lin L; Tian B; Vatner DE; Graham RM; Vatner SF, 2012, 'Cardiomyocyte overexpression of the á 1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning', American Journal of Physiology - Heart and Circulatory Physiology, 302, pp. H1614 - H1624, http://dx.doi.org/10.1152/ajpheart.01072.2011
Journal articles | 2011
Cannon L; Marciniec T; Mearns B; Vale M; Nikolova-Krstevski V; Kesteven S; Raynor S; Feneley M; Graham R; Fatkin D, 2011, 'A Regulatable Model of Mutant α-Myosin Heavy Chain Overexpression to Study the Structural and Functional Consequences of Hypertrophy Regression', Heart, Lung and Circulation, 20, pp. S1 - S1, http://dx.doi.org/10.1016/j.hlc.2011.05.004
Jabbour A; Gao L; Kwan JC; Watson A; Sun L; Qiu ; Liu X; Zhou MD; Graham RM; Hicks M; Macdonald PS, 2011, 'A recombinant human neuregulin-1 peptide improves preservation of the rodent heart after prolonged hypothermic storage', Transplantation, 91, pp. 961 - 967, http://dx.doi.org/10.1097/TP.0b013e3182115b4b
Skellett A; Gibbs S; Handfield-Jones S; Graham R; Tan E; Garioch J, 2011, 'Management of melanomas in primary care', British Journal of Dermatology, 164, pp. 680 - 682, http://dx.doi.org/10.1111/j.1365-2133.2010.10106.x
Journal articles | 2010
Chih SS; Macdonald P; McCrohon JA; Ma D; John M; Law M; Feneley MP; Herbert A; Kovacic JC; Graham RM; Victor Chang Cardiac Research Institute , 2010, 'GRANULOCYTE-COLONY STIMULATING FACTOR IN ANGINA PATIENTS WITH ISCHAEMIC HEART DIESASE TO STIMULATE NEOVASCULARISATION (GAIN II TRIAL)', Journal of the American College of Cardiology, 55, pp. A126.E1184 - A126.E1184, http://dx.doi.org/10.1016/s0735-1097(10)61185-0
Journal articles | 2010
Jabbour A; Hayward CS; Keogh AM; Kotlyar E; Mccrohon JA; England JF; Amor R; Liu X; Zhou MD; Graham RM; Macdonald PS, 2010, 'Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses', European Journal of Heart Failure, 13, pp. 83 - 92, http://dx.doi.org/10.1093/eurjhf/hfq152
Journal articles | 2010
Kirby A; Graham R; Williams NJ; Wootton M; Broughton CM; Alanazi M; Anson J; Neal TJ; Parry CM, 2010, 'Staphylococcus aureus with reduced glycopeptide susceptibility in Liverpool, UK', Journal of Antimicrobial Chemotherapy, 65, pp. 721 - 724, http://dx.doi.org/10.1093/jac/dkq009
Journal articles | 2010
Macbeth AE; James A; Rhodes M; Igali L; Mcgibbon D; Graham RM, 2010, 'Necrolytic migratory erythema with the absence of necrolysis', Clinical and Experimental Dermatology, 35, pp. 810 - 811, http://dx.doi.org/10.1111/j.1365-2230.2010.03824.x
Williams H; Pease RJ; Newell LM; Cordell PA; Graham RM; Kearney TK; Jackson CL; Grant PJ, 2010, 'Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse', Atherosclerosis, 210, pp. 94 - 99, http://dx.doi.org/10.1016/j.atherosclerosis.2009.11.014
Almaani N; Liu L; Dopping-Hepenstal PJC; Lovell PA; Lai-Cheong JE; Graham RM; Mellerio JE; McGrath JA, 2009, 'Autosomal dominant junctional epidermolysis bullosa', British Journal of Dermatology, 160, pp. 1094 - 1097, http://dx.doi.org/10.1111/j.1365-2133.2008.08977.x
Journal articles | 2009
Chih S; McCrohon J; Macdonald P; Feneley M; Graham RM, 2009, 'Exercise and Endothelial Progenitor Cells in Patients with Severe Coronary Artery Disease', Heart, Lung and Circulation, 18, pp. S112 - S113, http://dx.doi.org/10.1016/j.hlc.2009.05.255
Journal articles | 2009
Iismaa SE; Mearns BM; Lorand L; Graham RM, 2009, 'Transglutaminases and disease: Lessons from genetically engineered mouse models and inherited disorders', Physiological Reviews, 89, pp. 991 - 1023, http://dx.doi.org/10.1152/physrev.00044.2008
Journal articles | 2009
Jabbour A; Gao L; Kwan J; Watson A; Sun L; Liu X; Zhou M; Graham RM; Hicks M; Macdonald P, 2009, 'A Recombinant Human Neuregulin-1 Peptide Improves Preservation of the Transplanted Rat Heart After Prolonged Hypothermic Storage', Heart, Lung and Circulation, 18, pp. S168 - S168, http://dx.doi.org/10.1016/j.hlc.2009.05.382
Journal articles | 2009
Jabbour A; Hayward CS; Keogh AM; Kotlyar E; McCrohon J; England JF; Amor R; Liu X; Graham RM; Macdonald PS, 2009, 'The Safety and Efficacy of Recombinant Human Neuregulin-1 in Patients with Stable Chronic Heart Failure', Heart, Lung and Circulation, 18, pp. S192 - S192, http://dx.doi.org/10.1016/j.hlc.2009.05.436
Journal articles | 2009
Kovacic J; Macdonald PS; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, pp. e39, http://dx.doi.org/10.1016/j.aucc.2009.06.001
Journal articles | 2009
Kovacic JC; Macdonald P; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, http://dx.doi.org/10.1016/j.ahj.2009.02.009
Journal articles | 2009
MacDiarmid J; Amaro-Mugridge N; Madrid-Weiss J; Sedliarou I; Wetzel S; Kochar K; Brahmbhatt V; Phillips LN; Pattison S; Petti C; Stillman B; Graham RM; Brahmbhatt H, 2009, 'Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug', Nature Biotechnology, 27, pp. 643 - 651, http://dx.doi.org/10.1038/nbt.1547
Journal articles | 2009
Naqvi N; Li M; Yahiro E; Graham RM; Husain A, 2009, 'Insights into the characteristics of mammalian cardiomyocyte terminal differentiation shown through the study of mice with a dysfunctional c-kit', Pediatric Cardiology, 30, pp. 651 - 658, http://dx.doi.org/10.1007/s00246-008-9366-1
Journal articles | 2009
Tatsukawa H; Fukaya Y; Frampton G; Martinez-Fuentes A; Suzuki K; Kuo T; Nagatsuma K; Shimokado K; Okuno M; Wu J; Iismaa SE; Matsuura T; Tsukamoto H; Zern M; Graham RM; Kojima S, 2009, 'Role of Transglutaminase 2 in Liver Injury via Cross-linking and Silencing of Transcription Factor Sp1', Gastroenterology, 136, pp. 1783 - 1795, http://dx.doi.org/10.1053/j.gastro.2009.01.007
Journal articles | 2008
Amirahmadi F; Turnbull L; Du X; Graham RM; Woodcock EA, 2008, 'Heightened alpha(1A)-adrenergic receptor activity suppresses ischaemia/reperfusion-induced Ins(1,4,5)P-3 generation in the mouse heart: a comparison with ischaemic preconditioning', Clinical Science, 114, pp. 157 - 164, http://dx.doi.org/10.1042/C20070110
Journal articles | 2008
Amirahmadi F; Turnbull L; Du XJ; Graham RM; Woodcock EA, 2008, 'Heightened αIA-adrenergic receptor activity suppresses ischaemia/reperfusion-induced Ins(1,4,5)P3 generation in the mouse heart: A comparison with ischaemic preconditioning', Clinical Science, 114, pp. 157 - 164, http://dx.doi.org/10.1042/CS20070110
Journal articles | 2008
Cannon L; Marciniec T; Mearns B; Graham RM; Fatkin D, 2008, 'Abstract 3435: Left Ventricular Hypertrophy is Resistant to Inhibition of Expression of the R403Q Alpha-Myosin Heavy Chain Cardiac Hypertrophy-Inducing Mutant Protein', Circulation, 118, http://dx.doi.org/10.1161/circ.118.suppl_18.s_423-c
Journal articles | 2008
Chih S; Macdonald P; Fenely M; Law M; Graham R; McCrohon J, 2008, 'Reproducibility of Adenosine Stress Cardiac Magnetic Resonance Imaging by Normalised Upslope Analysis in Patients with Severe Coronary Artery Disease', Heart, Lung and Circulation, 17, pp. S47 - S48, http://dx.doi.org/10.1016/j.hlc.2008.05.109
Journal articles | 2008
Jabbour A; Gao L; Kwan J; Watson A; Liu X; Zhou M; Graham RM; Hicks M; Macdonald PS, 2008, 'IMPROVED PRESERVATION OF THE RAT HEART USING CELSIOR SOLUTION SUPPLEMENTED WITH A RECOMBINANT HUMAN NEUREGULIN-1 PEPTIDE', Transplantation, 86, pp. 55 - 56, http://dx.doi.org/10.1097/01.tp.0000332548.88129.5d
Kovacic JC; Macdonald PS; Feneley MP; Muller DW; Freund J; Dodds AJ; Milliken ST; Tao H; Itescu S; Moore JJ; Ma DD; Graham RM, 2008, 'Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD 133(+) cell infusion in patients with chronic refractory ischemic heart disease: The G-CSF in Angina patients with IHD to stimulate Neovascul', American Heart Journal, 156, pp. 954 - 963, http://dx.doi.org/10.1016/j.ahj.2008.04.034
Journal articles | 2008
Kovacic JC; Moore JJ; Herbert AD; Ma DD; Boehm M; Graham RM, 2008, 'Endothelial progenitor cells, angioblasts, and angiogenesis - Old terms reconsidered from a current perspective', Trends in Cardiovascular Medicine, 18, pp. 45 - 51, http://dx.doi.org/10.1016/j.tcm.2007.12.002
Journal articles | 2008
Li M; Naqvi N; Yahiro E; Liu KH; Powell P; Bradley W; Martin D; Dell Italia L; Graham RM; Husain A, 2008, 'c-kit is required for cardiomyocyte terminal differentiation', Circulation Research, 102, pp. 677 - 685, http://dx.doi.org/10.1161/CIRCRESAHA.107.161737
Journal articles | 2008
Riek RP; Finch A; Begg G; Graham RM, 2008, 'Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function', Molecular Pharmacology, 73, pp. 1092 - 1104, http://dx.doi.org/10.1124/mol.107.043042
Journal articles | 2008
Woodcock EA; Reichelt M; Du X; Graham RM, 2008, 'Cardiac alpha(1)-adrenergic drive in pathological remodelling', Cardiovascular Research, 77, pp. 452 - 462, http://dx.doi.org/10.1093/cvr/cvm078
Ju Y; Chu YH; Chaulet H; Lai D; Gervasio OL; Graham RM; Cannells M; Allen DG, 2007, 'Store-Operated Ca2+ Influx and Expression of TRPC Genes in Mouse Sinoatrial Node', Circulation Research, 100 (11), pp. 1605 - 1614, http://dx.doi.org/10.1161/CIRCRESAHA.107.152181
Kovacic JC; Macdonald P; Feneley MP; Muller DW; Ma D; Tao H; Freund J; Milliken S; Dodds A; Moore J; Itescu S; Graham RM, 2007, 'Abstract 2669: The Use of Granulocyte-Colony Stimulating Factor in Angina Patients to Stimulate Neovascularization: the GAIN I study', Circulation, 116, http://dx.doi.org/10.1161/circ.116.suppl_16.ii_591-d
Journal articles | 2007
Kovacic JC; Macdonald PS; Freund J; Rasko J; Allan RM; Fernandes VB; Ma DD; Moore JJ; Graham RM, 2007, 'Profound thrombocytopenia related to G-CSF', American Journal of Hematology, 82, pp. 229 - 230, http://dx.doi.org/10.1002/ajh.20787
Journal articles | 2007
Kovacic JC; Muller DW; Graham RM, 2007, 'Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease', Journal of Molecular and Cellular Cardiology, 42, pp. 19 - 33, http://dx.doi.org/10.1016/j.yjmcc.2006.10.001
Journal articles | 2007
MacDiarmid J; Mugridge N; Weiss J; Phillips LN; Burn AL; Paulin R; Haasdyk J; Dickson K; Brahmbhatt V; Pattison S; James AC; Al Bakri G; Straw R; Stillman B; Graham RM; Brahmbhatt H, 2007, 'Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics', Cancer Cell, 11, pp. 431 - 445, http://dx.doi.org/10.1016/j.ccr.2007.03.012
Journal articles | 2007
Strnad P; Harada M; Siegel M; Terkeltaub R; Graham RM; Khosla C; Omary M, 2007, 'Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement', Gastroenterology, 132, pp. 1515 - 1526, http://dx.doi.org/10.1053/j.gastro.2007.02.020
Journal articles | 2006
Begg G; Carrington L; Stokes P; Matthews JM; Wouters MA; Husain A; Lorand L; Iismaa SE; Graham RM, 2006, 'Mechanism of allosteric regulation of transglutaminase 2 by GTP', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 19683 - 19688, http://dx.doi.org/10.1073/pnas.0609283103
Journal articles | 2006
Begg G; Holman S; Stokes P; Matthews J; Graham RM; Iismaa SE; Holman , 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', The Journal of Biological Chemistry, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200
Journal articles | 2006
Begg GE; Holman SR; Stokes PH; Matthews JM; Graham RM; Iismaa SE, 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', JOURNAL OF BIOLOGICAL CHEMISTRY, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200
Journal articles | 2006
Chaulet H; Guo J; Owens WA; Michalicek J; Kesteven SH; Guan Z; Prall OW; Mearns BM; Feneley MP; Steinberg S; Graham RM, 2006, 'Sustained augmentation of cardiac alpha(1A)-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes', Journal of Molecular and Cellular Cardiology, 40, pp. 540 - 552, http://dx.doi.org/10.1016/j.yjmcc.2006.01.015
Journal articles | 2006
Du X; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Finch A; Hannan R; Dart A; Graham RM, 2006, 'Transgenic alpha(1A)-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival', Cardiovascular Research, 71, pp. 735 - 743, http://dx.doi.org/10.1016/j.cardiores.2006.06.015
Journal articles | 2006
Du XR; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Wang K; Finch A; Dart A; Graham RM, 2006, 'Cardiac overexpression of the alpha(1A)-adrenergic receptor limits post-infarct ventricular remodeling and dysfunction, and improves survival', Journal of Molecular and Cellular Cardiology, 41, pp. 735 - 735, http://dx.doi.org/10.1016/j.yjmcc.2006.06.022
Journal articles | 2006
Finch A; Graham RM, 2006, 'The alpha(1D)-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4, http://dx.doi.org/10.1124/mol.105.020230
Journal articles | 2006
Finch AM; Graham RM, 2006, 'The α1D-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4, http://dx.doi.org/10.1124/mol.105.020230
Journal articles | 2006
Iismaa S; Begg G; Graham RM, 2006, 'Cross-linking transglutaminases with G protein-coupled receptor signaling.', Science S Stke, 353, pp. pe34, http://dx.doi.org/10.1126/stke.3532006pe34
Journal articles | 2006
Liu X; Gu X; Li Z; Li X; Li H; Chang J; Chen PP; Jin J; Xi B; Chen D; Lai D; Graham RM; Zhou M, 2006, 'Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy', Journal of the American College of Cardiology, 48, pp. 1438 - 1447, http://dx.doi.org/10.1016/j.jacc.2006.05.057
Journal articles | 2006
Thomas AC; Cullup T; Norgett EE; Hill T; Barton S; Dale BA; Sprecher E; Sheridan E; Taylor AE; Wilroy RS; DeLozier C; Burrows N; Goodyear H; Fleckman P; Stephens KG; Mehta L; Watson RM; Graham R; Wolf R; Slavotinek A; Martin M; Bourn D; Mein CA; O'Toole EA; Kelsell DP, 2006, 'ABCA12 is the major harlequin ichthyosis gene', Journal of Investigative Dermatology, 126, pp. 2408 - 2413, http://dx.doi.org/10.1038/sj.jid.5700455
James M; Hoff T; Davis J; Graham R, 2005, 'Grant watch report: Leveraging the power of the media to combat HIV/AIDS: The Kaiser Family Foundation's partnerships with media and others to help educate the public about HIV/AIDS, here and abroad', Health Affairs, 24, pp. 854 - 857, http://dx.doi.org/10.1377/hlthaff.24.3.854
Journal articles | 2005
Kovacic JC; Graham RM, 2005, 'Are improvements in cardiac function due to stem cell uptake and engraftment?', American Journal of Cardiology, 95, pp. 159, http://dx.doi.org/10.1016/j.amjcard.2004.07.138
Journal articles | 2005
Kovacic JC; Muller DW; Harvey RJ; Graham RM, 2005, 'Update on the use of stem cells for cardiac disease', Internal Medicine Journal, 35, pp. 348 - 356, http://dx.doi.org/10.1111/j.1445-5994.2005.00840.x
Naqvi N; Liu KH; Graham RM; Husain A, 2005, 'Molecular basis of exopeptidase activity in the C-terminal domain ofhuman angiotensin I-converting enzyme - Insights into the origins ofits exopeptidase activity', The Journal of Biological Chemistry, 280, pp. 6669 - 6675, http://dx.doi.org/10.1074/jbc.M412638200
Journal articles | 2005
Wodak AD; Graham RM, 2005, 'Naltrexone implants as treatment for heroin dependence: Part II', Addiction Biology, 10, pp. 202 - 202
Journal articles | 2004
Cocks HJ; Kevans P; Graham RM; Brien JE, 2004, 'Evaluation of Therapeutic Drug Monitoring Services and Comparison of Two Models of Service Provision', Journal of Pharmacy Practice and Research, 34, pp. 109 - 113, http://dx.doi.org/10.1002/jppr200434290
Journal articles | 2004
Du X; Fang L; Gao X; Kiriazis H; Feng X; Hotchkin E; Finch AM; Chaulet H; Graham RM, 2004, 'Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction', Journal of Molecular and Cellular Cardiology, 37, pp. 979 - 987, http://dx.doi.org/10.1016/j.yjmcc.2004.07.010
Hwang K; Lim S; Kwon H; Bae Y; Kang S; Chung K; Graham RM; Rhee S; Jang Y, 2004, 'Phospholipase C-[delta]1 rescues intracellular Ca2+ overload in ischemic heart and hypoxic neonatal cardiomyocytes', Journal of Steroid Biochemistry and Molecular Biology, 91, pp. 131 - 138, http://dx.doi.org/10.1016/j.jsbmb.2004.02.009
Li M; Michalicek J; Angus JA; Hunt JE; Dell Italia L; Feneley MP; Graham RM; Husain A, 2004, 'Involvement of chymase-mediated angiotensin II generation in blood pressure regulation', Journal of Clinical Investigation, 114, pp. 112 - 120, http://dx.doi.org/10.1172/JCI200420805
Journal articles | 2004
Palmieri C; Vigushin D; Coombes RC; Kim HS; Kang HJ; Park YB; Kovacic JC; Graham RM, 2004, 'Stem-cell therapy for myocardial diseases [4] (multiple letters)', Lancet, 363, pp. 1734 - 1735, http://dx.doi.org/10.1016/s0140-6736(04)16268-5
Bailey CD; Graham RM; Nanda N; Davies PJ; Johnson GV, 2003, 'Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases', Molecular and Cellular Neuroscience, 25, pp. 493 - 503, http://dx.doi.org/10.1016/j.mcn.2003.11.016
Journal articles | 2003
Husain A; Li M; Graham RM, 2003, 'Do studies with ACE N- and C-Fomain-Selective Inhibitors provide evidence for a non-ACE, non-chymase Angiotensin II-forming pathway?', Circ Res, 93, pp. 91 - 93, http://dx.doi.org/10.1161/01.RES.0000084993.90444.6C
Journal articles | 2003
Iismaa SE; Graham RM, 2003, 'Dissecting cardiac hypertrophy and signalling pathways: evidence for an interaction between multifunctional G proteins and prostanoids', Corc Res, 92, pp. 1059 - 1061, http://dx.doi.org/10.1161/01.RES.0000075792.92001.D4
Journal articles | 2003
Iismaa SE; Holman S; Wouters MA; Lorand L; Graham RM; Husain A; Holman , 2003, 'Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases', Proceedings of the National Academy of Sciences of the United States of America, 22, pp. 12636 - 12641, http://dx.doi.org/10.1073/pnas.1635052100
Journal articles | 2003
Johnson K; Van Elten D; Nanda N; Graham RM; Terkeltaub R, 2003, 'Distinct transglutaminase II/TG2-independent and TG2-dependent pathways mediate articular chondrocyte hypertrophy', The Journal of Biological Chemistry, 21, pp. 18824 - 18832, http://dx.doi.org/10.1074/jbc.M301055200
Journal articles | 2003
Ju Y; Wu M; Chaulet H; Graham RM; Allen DG, 2003, 'IGF-1 enhances store-operated Ca2+ channel activity in skeletal myoblasts : possible involvement of a CD20-like protein', Journal of Cell Physiol, 197, pp. 53 - 60
Journal articles | 2003
Ju YK; Wu MJ; Chaulet H; Marciniec T; Graham RM; Allen DG, 2003, 'IGF-1 Enhances a Store-Operated Ca2+ Channel in Skeletal Muscle Myoblasts: Involvement of a CD20-Like Protein', Journal of Cellular Physiology, 197, pp. 53 - 60, http://dx.doi.org/10.1002/jcp.10347
Journal articles | 2003
Lin F; Owens AW; Kesteven SH; Michalicek J; Chen S; Graham RM; Feneley MP, 2003, 'Cardiac-targeted overexpression of the α1A-AR results in premature death: A potential model of electromechanical dissociation', Heart, Lung and Circulation, 12, pp. A59 - A59, http://dx.doi.org/10.1046/j.1443-9506.2003.02393.x
Journal articles | 2003
Lorand L; Graham RM, 2003, 'Transglutaminases: crosslinking enzymes with pleiotropic functions.', Nature Reviews Molecular Cell Biology, 4, pp. 140 - 156, http://dx.doi.org/10.1038/nrm1014
Journal articles | 2003
Rigoutsos I; Riek RP; Graham RM; Novotny J, 2003, 'Structural details (kinks and non-a-helical conformations) in transmembrane helices are intrahelically determined and can be predicted by sequence pattern descriptors.', Nucleic Acids Research, 15, pp. 4625 - 4631, http://dx.doi.org/10.1093/nar/gkg639
Journal articles | 2003
Sharpe IA; Thomas L; Loughnan M; Motin L; Palant E; Croker DE; Alewood D; Chen S; Graham RM; Alewood P; Adams DJ; Lewis RA, 2003, 'Allosteric á1-adrenoceptor antagonism by the conopeptide ñ-TIA', The Journal of Biological Chemistry, 278, pp. 34451 - 34457, http://dx.doi.org/10.1074/jbc.M305410200
Journal articles | 2002
Chen S; Lin F; Xu M; Graham RM, 2002, 'Phe303 in TMVI of the α1B-adrenergic receptor is a key residue coupling TM helical movements to G-protein activation', Biochemistry, 41, pp. 588 - 596, http://dx.doi.org/10.1021/bi011868k
Journal articles | 2002
Chen S; Lin FF; Xu M; Riek RP; Novotny J; Graham RM, 2002, 'Mutation of a single TMVI residue, Phe282, in the β2-adrenergic receptor results in structurally distinct activated receptor conformations', Biochemistry, 41, pp. 6045 - 6053, http://dx.doi.org/10.1021/bi012189c
Graham GG; Graham RM; Day RO, 2002, 'Comparative analgesia, cardiovascular and renal effects of celecoxib, rofecoxib and acetaminophen (paracetamol)', Current Pharmaceutical Design, 8, pp. 1063 - 1075, http://dx.doi.org/10.2174/1381612023394917
Khumalo NP; Loo WJ; Hollowood K; Salvary I; Graham RM; Dawber RPR, 2002, 'Keratosis pilaris atrophicans in mother and daughter', Journal of the European Academy of Dermatology and Venereology, 16, pp. 397 - 400, http://dx.doi.org/10.1046/j.1468-3083.2002.00472.x
Murthy SN; Iismaa SE; Begg G; Freymann DM; Graham RM; Lorand L, 2002, 'Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity.', Proceedings of the National Academy of Sciences of the United States of America, 99, pp. 2738 - 2742, http://dx.doi.org/10.1073/pnas.052715799
Journal articles | 2001
Chen S; Lin F; Xu M; Graham RM, 2001, 'Phe303 in transmembrane segment VI of the a1B-adrenergic receptor is a key switchresidue coupling transmembrane helical movements to G protein activation', Biochemistry, pp. 588 - 596
Fatkin D; Graham RM; Spirito P; Maron BJ, 2001, 'Prognostic value of left ventricular hypertrophy in hypertrophic cardiomyopathy', New England Journal of Medicine, 344, pp. 63 - 65, http://dx.doi.org/10.1056/NEJM200101043440115
Journal articles | 2001
Lin F; Owens WA; Chen S; Stevens ME; Kesteven S; Arthur JF; Woodcock EA; Feneley MP; Graham RM, 2001, 'Targeted a1A-Adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy.', Circ Res, 89, pp. 343 - 350, http://dx.doi.org/10.1161/hh1601.095912
Journal articles | 2001
Nanda N; Iismaa SE; Owens WA; Husain A; Mackay F; Graham RM, 2001, 'Targeted inactivation of Gh/Transglutaminase II', The Journal of Biological Chemistry, 276, pp. 20673 - 20678, http://dx.doi.org/10.1074/jbc.M010846200
Journal articles | 2001
Nanda N; Iismaa SE; Owens WA; Husain A; Mackay F; Graham RM, 2001, 'Targeted inactivation of Gh/tissue transglutaminase II', The Journal of Biological Chemistry, pp. 20673 - 20678
Journal articles | 2001
Riek RP; Rigoutsos I; Novotny J; Graham RM, 2001, 'Non-a-helical elements drive diversity of polytopic membrane protein architecture', Journal of Molecular Biology, pp. 349 - 362
Journal articles | 2001
Riek RP; Rigoutsos I; Novotny J; Graham RM, 2001, 'Non-α-helical elements modulate polytopic membrane protein architecture', Journal of Molecular Biology, 306, pp. 349 - 362, http://dx.doi.org/10.1006/jmbi.2000.4402
Journal articles | 2000
Azurdia RM; Graham RM; Weismann K; Guerin DM; Parslew R, 2000, 'Acne keloidalis in caucasian patients on cyclosporin following organ transplantation [15]', British Journal of Dermatology, 143, pp. 465 - 466, http://dx.doi.org/10.1046/j.1365-2133.2000.03694.x
Journal articles | 2000
Chen S; Lin F; Xu M; Hwa J; Graham RM, 2000, 'Dominant-negative activity of an α(1β)-adrenergic receptor signal-inactivating point mutation', EMBO Journal, 19, pp. 4265 - 4271
Journal articles | 2000
Corkill JE; Graham R; Hart CA; Stubbs S, 2000, 'Pulsed-field gel electrophoresis of degradation-sensitive DNAs from Clostridium difficile PCR ribotype 1 strains', Journal of Clinical Microbiology, 38, pp. 2791 - 2792, http://dx.doi.org/10.1128/jcm.38.7.2791-2792.2000
Journal articles | 2000
Iismaa S; Wu M; Nanda N; Church WB; Graham RM, 2000, 'GTP binding and signaling by Gh/transglutaminase II involves distinct residues in a unique GTP-binding pocket.', The Journal of Biological Chemistry, 275, pp. 18259 - 18265, http://dx.doi.org/10.1074/jbc.M000583200
Chen S; Xu M; Lin F; Lee D; Riek P; Graham RM, 1999, 'Phe310 in transmembrane VI of the α(1B)-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding', Journal of Biological Chemistry, 274, pp. 16320 - 16330, http://dx.doi.org/10.1074/jbc.274.23.16320
Journal articles | 1999
Chen S; Xu M; Lin F; Lee DJ; Riek RP; Graham RM, 1999, 'Phe310 in Transmembrane VI of the alpha1B-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding', The Journal of Biological Chemistry, 274, pp. 16320 - 16330, https://www.ncbi.nlm.nih.gov/pubmed/10347189
Journal articles | 1999
Graham RM; Owens WA, 1999, 'Pathogenesis of inherited forms of dilated cardiomyopathy', New England Journal of Medicine, 341, pp. 1759 - 1762, http://dx.doi.org/10.1056/NEJM199912023412309
Journal articles | 1999
Nanda N; Iismaa SE; Copeland NG; Gilbert DM; Jenkins NA; Graham RM; Sutrave P, 1999, 'Organisation and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2)', Archives of Biochemistry and Biophysics, 366, pp. 151 - 156, http://dx.doi.org/10.1006/abbi.1999.1189
Journal articles | 1999
Semsarian C; Sutrave P; Richmond DR; Graham RM, 1999, 'Insulin-like growth facor (IGF-1) induces myotube hypertrophy associated with an increase in anaerobic glycolysis in skeletal muscle cell model', Biochemical Journal, 339, pp. 443 - 451, http://dx.doi.org/10.1042/0264-6021:3390443
Journal articles | 1999
Semsarian C; Wu M; Ju Y; Marciniec T; Yeoh T; Allen D; Harvey RJ; Graham RM, 1999, 'Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway', Nature, 400, pp. 576 - 581, http://dx.doi.org/10.1038/23054
Cao LY; Zhang L; Ruiz-Lozano P; Yang Q; Chien KR; Graham RM; Zhou M, 1998, 'A novel putative protein-tyrosine phosphate contains a BRO1-like domain and suppresses Ha-ras-mediated transformation', The Journal of Biological Chemistry, 273, pp. 21077 - 21083, http://dx.doi.org/10.1074/jbc.273.33.21077
Journal articles | 1998
Frank J; McGrath J; Lam H; Graham RM; Hawk JLM; Christiano AM, 1998, 'Homozygous variegate porphyria: Identification of mutations on both alleles of the protoporphyrinogen oxidase gene in a severely affected proband', Journal of Investigative Dermatology, 110, pp. 452 - 455, http://dx.doi.org/10.1046/j.1523-1747.1998.00148.x
Journal articles | 1998
Grayson TH; Ellis JM; Chen SH; Graham RM; Brown RD; Hill CE, 1998, 'Immunohistochemical localisation of alpha(1B)-adrenergic receptors in the rat iris', Cell and Tissue Research, 293, pp. 435 - 444, http://dx.doi.org/10.1007/s004410051135
Journal articles | 1998
Liu X; Hwang H; Cao L; Wen D; Liu N; Graham RM; Zhou M, 1998, 'Release of the neuregulin functional polypeptide requires its cytoplasmic tail', Journal of Biological Chemistry, 273, pp. 34335 - 34340, http://dx.doi.org/10.1074/jbc.273.51.34335
Journal articles | 1998
Liu X; Hwang H; Cao LY; Buckland M; Cunningham AL; Chen JG; Chien KR; Graham RM; Zhou M, 1998, 'Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 13024 - 13029, http://dx.doi.org/10.1073/pnas.95.22.13024
Journal articles | 1997
Graham RM, 1997, 'More supernumeraries?', British dental journal, 183, pp. 49
Journal articles | 1997
Iismaa S; Chung L; Wu M; Teller DC; Yee VC; Graham RM, 1997, 'The core domain of the tissue transglutaminase, Gh, hydrolyzes GTP and ATP', Biochemistry, 36, pp. 11655 - 11664, http://dx.doi.org/10.1021/bi970545e
Journal articles | 1997
McGrath JA; Hawk JLM; Graham RM; Christiano AM, 1997, 'Lack of the R59W South African founder effect mutation in protoporphyrinogen oxidase in a British patient with homozygous variegate porphyria [7]', British Journal of Dermatology, 136, pp. 292, http://dx.doi.org/10.1111/j.1365-2133.1997.tb14923.x
Journal articles | 1996
Chen S; Lin F; Iismaa S; Lee KN; Birckbichler PJ; Graham RM, 1996, 'α1-adrenergic receptor signaling via G(h) is subtype specific and independent of its transglutaminase activity', Journal of Biological Chemistry, 271, pp. 32385 - 32391, http://dx.doi.org/10.1074/jbc.271.50.32385
Journal articles | 1996
Chen S; Lin F; Iismaa SE; Lee K; Birckbichler PJ; Graham RM, 1996, 'Alpha1-Adrenergic receptor signalling via Gh is subtype-specific and independent of its transglutaminase activity', The Journal of Biological Chemistry, 271, pp. 32385 - 32391, https://www.ncbi.nlm.nih.gov/pubmed/8943303
Graham RM; Neubig R; Lynch KR, 1996, 'α2-Adrenoceptors take centre stage at Nashville meeting', Trends in Pharmacological Sciences, 17, pp. 90 - 94, http://dx.doi.org/10.1016/0165-6147(96)30004-7
Journal articles | 1996
Graham RM; Perez DM; Hwa J; Piascik MT, 1996, '1-Adrenergic receptor subtypes: molecular structure, function and signalling', Circulation Research, pp. 737 - 749
Journal articles | 1996
Graham RM; Perez DM; Hwa J; Piascik MT, 1996, 'alpha(1)-Adrenergic receptor subtypes - Molecular structure, function, and signaling', CIRCULATION RESEARCH, 78, pp. 737 - 749, http://dx.doi.org/10.1161/01.RES.78.5.737
Journal articles | 1996
Graham RM; Perez DM; Hwa J; Piascik MT, 1996, 'α1-Adrenergic Receptor Subtypes Molecular Structure, Function, and Signaling', Circulation Research, 78, pp. 737 - 749, http://dx.doi.org/10.1161/01.RES.78.5.737
Hwa J; Graham RM; Perez DM, 1996, 'Chimeras of 1-adrenergic receptor subtypes indentify critical residues that modulate active-state isomerization', The Journal of Biological Chemistry, 271, pp. 7956 - 7964, http://dx.doi.org/10.1074/jbc.271.14.7956
Journal articles | 1996
Karnik SS; Husain A; Graham RM, 1996, 'Molecular determinants of peptide and non-peptide binding to the AT1 receptor', Clinical and Experimental Pharmacology and Physiology, 23
Journal articles | 1996
Perez DM; Hwa J; Gaivin R; Mathur M; Brown F; Graham RM, 1996, 'Consitutive activity of a single transduction pathway due to a point-mutation in the 1B-adrenergic receptor', Molecular Pharmacology, pp. 112 - 122
Journal articles | 1996
Perez DM; Hwa J; Gaivin R; Mathur M; Brown F; Graham RM, 1996, 'Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor', Molecular Pharmacology, 49, pp. 112 - 122
Journal articles | 1996
Pollak MR; Delaney VB; Graham RM; Hebert SC, 1996, 'Gitelman`s syndrome (Bartters variant) maps to the thiazide-sensitive cotransporter gene locus on chromosone 16q13 in a large kindred', Journal of the American Society of Nephrology, 7, pp. 2244 - 2248
Journal articles | 1995
DeS Senanayake P; Denker J; Bravo EL; Graham RM, 1995, 'Production, characterization, and expression of neuropeptide Y by human pheochromocytoma', Journal of Clinical Investigation, 96, pp. 2503 - 2509, http://dx.doi.org/10.1172/JCI118310
Journal articles | 1995
Des Senanayake P; Denker J; Bravo EL; Graham RM, 1995, 'The distribution and release of neuropeptide Y from adrenal and extraadrenal pheochromocytomas', Journal of Clinical Investigation, pp. 2503 - 2509
Journal articles | 1995
Graham RM; Perez DM; Piascik MT; Riek RP; Hwa J, 1995, 'Characterisation of α1-adrenergic receptor subtypes', Pharmacology Communications, 6, pp. 15 - 22
Hasebe N; Hittinger L; Kohin S; Shen YT; Graham RM; Vatner SF, 1995, 'Effects of hypertrophy on left atrial and ventricular compliance and plasma ANF levels in conscious dogs', American Journal of Physiology - Heart and Circulatory Physiology, 268, http://dx.doi.org/10.1152/ajpheart.1995.268.2.h781
Journal articles | 1995
Hwa J; Graham RM; Perez DM, 1995, 'Critical determinants of a -adrenergic receptor subtype-selective ahonist binding', The Journal of Biological Chemistry, pp. 23189 - 23195
Journal articles | 1995
Hwa J; Graham RM; Perez DM, 1995, 'Identification of critical determinants of α1-adrenergic receptor subtype selective agonist binding', Journal of Biological Chemistry, 270, pp. 23189 - 23195, http://dx.doi.org/10.1074/jbc.270.39.23189
Journal articles | 1995
Kerr JR; Moore JE; Curran MD; Graham R; Web CH; Lowry KG; Murphy PG; Wilson TS; Ferguson WP, 1995, 'Investigation of a nosocomial outbreak of Pseudomonas aeruginosa pneumonia in an intensive care unit by random amplification of polymorphic DNA assay', Journal of Hospital Infection, 30, pp. 125 - 131, http://dx.doi.org/10.1016/0195-6701(95)90152-3
Journal articles | 1995
Noda K; Saad YM; Kinoshita A; Graham RM; Boyle T; Husain A; Karnik S, 1995, 'Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms', The Journal of Biological Chemistry, 270, pp. 2284 - 2289, http://dx.doi.org/10.1074/jbc.270.5.2284
Riek RP; Handschumacher MK; Sung S; Tan M; Glynias MJ; Schluchter MD; Novotny J; Graham RM, 1995, 'Evolutionary conservation of both the hydrophilic and hydrophobic nature of transmembrance residues', Journal of Theoretical Biology, 172, pp. 245 - 258, http://dx.doi.org/10.1006/jtbi.1995.0021
Journal articles | 1995
Vincan E; Neylon CB; Graham RM; Woodcock EA, 1995, 'Isolatin of neonatal cardiomyocytes reduces the expression of the GTP-binding protein Gh', Journal of Molecular and Cellular Cardiology, 27, pp. 2393 - 2396, http://dx.doi.org/10.1016/S0022-2828(95)92127-3
Journal articles | 1994
Casale PN; Fifer MA; Graham RM; Palacios IF, 1994, 'Relation of atrial pressure and plasma level of atrial natriuretic factor in cardiac tamponade', The American Journal of Cardiology, 73, pp. 610 - 613, http://dx.doi.org/10.1016/0002-9149(94)90346-8
Journal articles | 1994
De Young MB; Keller JC; Graham RM; Wildey GM, 1994, 'Brefeldin A defines distinct pathways for atrial natriuretic factor secretion in neonatal rat atrial and ventricular myocytes', Circulation Research, 74, pp. 33 - 40, http://dx.doi.org/10.1161/01.RES.74.1.33
Journal articles | 1994
De Young MB; Kincade-Denker J; Boehm CA; Riek RP; Mamone JA; McSwiggen JA; Graham RM, 1994, 'Functional Characterization of Ribozymes Expressed Using U1 and T7 Vectors for the Intracellular Cleavage of ANF mRNA', Biochemistry, 33, pp. 12127 - 12138, http://dx.doi.org/10.1021/bi00206a016
Journal articles | 1994
Graham RM, 1994, 'Cyclosporine: Mechanisms of action and toxicity', Cleveland Clinic Journal of Medicine, 61, pp. 308 - 313, http://dx.doi.org/10.3949/ccjm.61.4.308
Journal articles | 1994
Nakaoka H; Perez DM; Baek KJ; Das T; Husain A; Misono K; Im MJ; Graham RM, 1994, 'Gh: A GTP-Binding protein with transglutaminase activity and receptor signaling function', Science, 264, pp. 1593 - 1596, http://dx.doi.org/10.1126/science.7911253
Journal articles | 1994
Noda K; Saad Y; Graham RM; Karnik SS, 1994, 'The high affinity state of the β2-adrenergic receptor requires unique interaction between conserved and non-conserved extracellular loop cysteines', Journal of Biological Chemistry, 269, pp. 6743 - 6752
Journal articles | 1994
Perez DM; Piascik MT; Malik N; Gaivin R; Graham RM, 1994, 'Cloning, expression, and tissue distribution of the rat homolog of the bovine α(1C)-adrenergic receptor provide evidence for its classification as the α(1A) subtype', Molecular Pharmacology, 46, pp. 823 - 831
Journal articles | 1993
Graham RM, 1993, 'F. Merlin Bumpus, PhD.', Cleveland Clinic journal of medicine, 60, pp. 417 - 418
Journal articles | 1993
Perez DM; DeYoung MB; Graham RM, 1993, 'Coupling of expressed α(1B)- and α(1D)-adrenergic receptors to multiple signaling pathways is both G protein and cell type specific', Molecular Pharmacology, 44, pp. 784 - 795
Journal articles | 1993
Urata H; Karnik SS; Graham RM; Husain A, 1993, 'Dipeptide processing activates recombinant human prochymase', Journal of Biological Chemistry, 268, pp. 24318 - 24322
Journal articles | 1992
Franke RR; Sakmar TP; Graham RM; Khorana HG, 1992, 'Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin', Journal of Biological Chemistry, 267, pp. 14767 - 14774
Journal articles | 1992
Kiuchi K; Vatner DE; Uemura N; Bigaud M; Hasebe N; Hempel DM; Graham RM; Vatner SF, 1992, 'Mechanisms of α1-adrenergic vascular desensitization in conscious dogs', Circulation Research, 71, pp. 1185 - 1199, http://dx.doi.org/10.1161/01.RES.71.5.1185
Journal articles | 1992
Ramarao CS; Denker JMK; Perez DM; Gaivin RJ; Riek RP; Graham RM, 1992, 'Genomic organization and expression of the human α(1B)-adrenergic receptor', Journal of Biological Chemistry, 267, pp. 21936 - 21945
Journal articles | 1991
Kaye SB; Graham R; McCarthy K; Green JR; Damjanovic V; Austin M, 1991, 'Reducing disinfectant wastage', Eye (Basingstoke), 5, pp. 120 - 123, http://dx.doi.org/10.1038/eye.1991.22
Journal articles | 1991
Perez DM; Piascik MT; Graham RM, 1991, 'Solution-phase library screening for the identification of rare clones: Isolation of an α(1D)-adrenergic receptor cDNA', Molecular Pharmacology, 40, pp. 876 - 883
Journal articles | 1991
Shannon RP; Gelpi RJ; Hittinger L; Vatner DE; Homcy CJ; Graham RM; Vatner SF, 1991, 'Inotropic response to norepinephrine is augmented early and maintained late in conscious dogs with perinephritic hypertension', Circulation Research, 68, pp. 543 - 554, http://dx.doi.org/10.1161/01.RES.68.2.543
Journal articles | 1991
Shen YT; Graham RM; Vatner SF, 1991, 'Effects of atrial natriuretic factor on blood flow distribution and vascular resistance in conscious dogs', American Journal of Physiology - Heart and Circulatory Physiology, 260, http://dx.doi.org/10.1152/ajpheart.1991.260.6.h1893
Journal articles | 1991
Urata H; Kinoshita A; Perez DM; Misono KS; Bumpus FM; Graham RM; Husain A, 1991, 'Cloning of the gene and cDNA for human heart chymase', Journal of Biological Chemistry, 266, pp. 17173 - 17179
Journal articles | 1990
Graham RM, 1990, 'Adrenergic receptors: Structure and function', Cleveland Clinic Journal of Medicine, 57, pp. 481 - 492, http://dx.doi.org/10.3949/ccjm.57.5.481
Journal articles | 1990
Im MJ; Graham RM, 1990, 'A novel guanine nucleotide-binding protein coupled to the α1-adrenergic receptor. I. Identification by photolabeling of membrane and ternary complex preparations', Journal of Biological Chemistry, 265, pp. 18944 - 18951
Journal articles | 1990
Im MJ; Riek RP; Graham RM, 1990, 'A novel guanine nucleotide-binding protein coupled to the α1-adrenergic receptor. II. Purification, characterization, and reconstitution', Journal of Biological Chemistry, 265, pp. 18952 - 18960
Journal articles | 1990
Shen YT; Young MA; Ohanian J; Graham RM; Vatner SF, 1990, 'Atrial natriuretic factor-induced systemic vasoconstriction in conscious dogs, rats, and monkeys', Circulation Research, 66, pp. 647 - 661, http://dx.doi.org/10.1161/01.RES.66.3.647
Journal articles | 1990
Terman BI; Riek RP; Grodski A; Hess HJ; Graham RM, 1990, 'Identification and structural characterization of α1-adrenergic receptor subtypes', Molecular Pharmacology, 37, pp. 526 - 534
Journal articles | 1990
Wildey GM; Fischman AJ; Margolies MN; Graham RM; Homcy CJ, 1990, 'Phosphorylation state of pro-atrial natriuretic factor in rat atrial secretory granules', Endocrinology, 127, pp. 2839 - 2848, http://dx.doi.org/10.1210/endo-127-6-2839
Journal articles | 1989
Aspinall ST; Graham R, 1989, 'Two sources of contamination of a hydrotherapy pool by environmental organisms', Journal of Hospital Infection, 14, pp. 285 - 292, http://dx.doi.org/10.1016/0195-6701(89)90068-6
Journal articles | 1989
Forbes AM; Woodrow JC; Verbov JL; Graham RM, 1989, 'Carcinoma of breast and scleroderma: Four further cases and a literature review', Rheumatology, 28, pp. 65 - 69, http://dx.doi.org/10.1093/rheumatology/28.1.65
Graham RM, 1989, 'Selective alpha1-adrenergic blockade, lipids, and coronary heart disease risk. Considerations in the treatment of mild hypertension', The American Journal of Medicine, 87, http://dx.doi.org/10.1016/0002-9343(89)90114-9
Journal articles | 1989
Karge WH; Weiner EJ; Kowala MC; Graham RM; Nicolosi RJ, 1989, 'Effects of prazosin on hemodynamics, hemostasis, and serum lipid and lipoprotein levels in normal and hypercholesterolemic monkeys', The American Journal of Medicine, 86, pp. 19 - 23, http://dx.doi.org/10.1016/0002-9343(89)90123-X
Ohanian J; Young MA; Shen YT; Gaivin R; Vatner SF; Graham RM, 1989, 'Natriuretic and diuretic effects of infusion of atrial natriuretic factor in conscious dogs', American Journal of Physiology - Renal Fluid and Electrolyte Physiology, 257, http://dx.doi.org/10.1152/ajprenal.1989.257.4.f565
Journal articles | 1989
Parini A; Coupry I; Graham RM; Uzielli I; Atlas D; Lanier SM, 1989, 'Characterization of an imidazoline/guanidinium receptive site distinct from the α2-adrenergic receptor', Journal of Biological Chemistry, 264, pp. 11874 - 11878
Journal articles | 1989
Parini A; Graham RM, 1989, 'Glycerol, sodium phosphate, and sodium chloride permit the solubilization and partial purification of rat hepatic α1-receptors by 3-(3-cholamidylpropyl)-dimethylammonio-1-propanesulfonate', Analytical Biochemistry, 176, pp. 375 - 381, http://dx.doi.org/10.1016/0003-2697(89)90327-8
Journal articles | 1988
Camazine B; Shannon RP; Guerrero JL; Graham RM; Powell WJ, 1988, 'Neurogenic histaminergic vasodilation in canine skeletal muscle: Mediation by α2-adrenoceptor stimulation', Circulation Research, 62, pp. 871 - 883, http://dx.doi.org/10.1161/01.RES.62.5.871
Journal articles | 1988
Dimsdale J; Ziegler M; Graham R, 1988, 'The effect of hypertension, sodium, and race on isoproterenol sensitivity', Clinical and Experimental Hypertension - Part A Theory and Practice, 10, pp. 747 - 756, http://dx.doi.org/10.1080/07300077.1988.11878781
Journal articles | 1988
Fischman AJ; Wildey GM; Matsueda GR; Margolies MN; Zisfein JB; Homcy CJ; Graham RM, 1988, 'Specificity of serine proteases for cleavage sites on proatrial natriuretic factor', Peptides, 9, pp. 1275 - 1283, http://dx.doi.org/10.1016/0196-9781(88)90192-1
Journal articles | 1988
Graham R; Palmer D; Pratt BC; Hart CA, 1988, 'In vitro activity of florphenicol', European Journal of Clinical Microbiology & Infectious Diseases, 7, pp. 691 - 694, http://dx.doi.org/10.1007/BF01964257
Journal articles | 1988
Graham RM; Sena LM; Longabaugh JP; Sawutz DG; Schwarz KR; Homcy CJ, 1988, 'Coupling of the α1-adrenergic receptor to a guanine nucleotide-binding regulatory protein by a discrete domain distinct from its ligand recognition site', BBA - Molecular Cell Research, 968, pp. 119 - 126, http://dx.doi.org/10.1016/0167-4889(88)90051-1
Lanier SM; Homcy CJ; Patenaude C; Graham RM, 1988, 'Identification of structurally distinct α2-adrenergic receptors', Journal of Biological Chemistry, 263, pp. 14491 - 14496
Journal articles | 1988
Muntz KH; Calianos TA; Buja LM; Willerson JT; Bernatowicz M; Homcy CJ; Graham RM, 1988, 'Electron microscopic localization of the β-adrenergic receptor using a ferritin-alprenolol probe', Molecular Pharmacology, 34, pp. 444 - 451
Journal articles | 1988
Supple EW; Graham RM; Powell WJ, 1988, 'Direct effects of α2-adrenergic receptor stimulation on intravascular systemic capacity in the dog', Hypertension, 11, pp. 352 - 359, http://dx.doi.org/10.1161/01.HYP.11.4.352
Journal articles | 1988
Svetkey LP; Brobyn R; Deedwania P; Graham RM; Morganroth J; Klotman PE, 1988, 'Double-blind comparison of doxazosin, nadolol, and placebo in patients with mild-to-moderate hypertension', Current Therapeutic Research - Clinical and Experimental, 43, pp. 969 - 978
Journal articles | 1988
Waldman HM; Palacios IF; Block PC; Wilkins GT; Homcy CJ; Graham RM; Fifer MA, 1988, 'Responsiveness of Plasma Atrial Natriuretic Factor to Short-Term Changes in Left Atrial Hemodynamics After Percutaneous Balloon Mitral Valvuloplasty', Journal of the American College of Cardiology, 12, pp. 649 - 655, http://dx.doi.org/10.1016/S0735-1097(88)80051-2
Journal articles | 1988
Wildey GM; Fischman AJ; Fallon JT; Matsueda GR; Zisfein JB; Preibisch G; Seipke G; Homcy CJ; Graham RM, 1988, 'Cellular processing of pro-atrial natriuretic factor (PRO-ANF): Studies using an antiserum that selectively binds anf-(99-126) after its cleavage from pro-anf', Endocrinology, 123, pp. 2054 - 2061, http://dx.doi.org/10.1210/endo-123-4-2054
Journal articles | 1988
Young MA; Vatner DE; Knight DR; Graham RM; Homcy CJ; Vatner SF, 1988, 'α-Adrenergic vasoconstriction and receptor subtypes in large coronary arteries of calves', American Journal of Physiology - Heart and Circulatory Physiology, 255
Journal articles | 1987
Allen KD; Bartzokas CA; Graham R; Gibson MF; Gilbertson AA, 1987, 'Acquisition of endemic Pseudomonas aeruginosa on an intensive therapy unit', Journal of Hospital Infection, 10, pp. 156 - 164, http://dx.doi.org/10.1016/0195-6701(87)90142-3
Journal articles | 1987
Bloch KD; Zisfein JB; Margolies MN; Homcy CJ; Seidman JG; Graham RM, 1987, 'A serum protease cleaves proANF into a 14-kilodalton peptide and ANF', American Journal of Physiology - Endocrinology and Metabolism, 252, http://dx.doi.org/10.1152/ajpendo.1987.252.1.e147
Journal articles | 1987
Dimsdale JE; Graham RM; Ziegler MG; Zusman RM; Berry CC, 1987, 'Age, race, diagnosis, and sodium effects on the pressor response to infused norepinephrine', Hypertension, 10, pp. 564 - 569, http://dx.doi.org/10.1161/01.HYP.10.6.564
Journal articles | 1987
Flanigan T; Shapiro E; Graham R, 1987, 'Prophylaxis against Pneumocystis carinii Pneumonia in Patients Receiving Azidothymidine', New England Journal of Medicine, 317, pp. 1155, http://dx.doi.org/10.1056/NEJM198710293171812
Journal articles | 1987
GRAHAM RM; MACFARLANE AW; CURLEY RK; NASH JRG, 1987, 'β 2 Microglobulin expression in keratoacanthomas and squamous cell carcinoma', British Journal of Dermatology, 117, pp. 441 - 449, http://dx.doi.org/10.1111/j.1365-2133.1987.tb04923.x
Lanier SM; Graham RM; Hess HJ; Grodski A; Repaske MG; Nunnari JM; Limbird LE; Homcy CJ, 1987, 'Synthesis and characterization of arylamine derivatives of rauwolscine as molecular probes for α 2 -adrenergic receptors', Hypertension, 9, pp. III-120-III-124
Journal articles | 1987
Lanier SM; Graham RM; Hess HJ; Grodski A; Repaske MG; Nunnari JM; Limbird LE; Homcy CJ, 1987, 'Synthesis and characterization of arylamine derivatives of rauwolscine as molecular probes for α<inf>2</inf>-adrenergic receptors', Hypertension, 9, pp. III-120-III-124
Ng HWK; MacFarlane AW; Graham RM; Verbov JL, 1987, 'Near fatal drug interactions with methotrexate given for psoriasis', British Medical Journal, 295, pp. 752 - 753
Journal articles | 1987
Ohanian J; Nicolosi RJ; Vatner SF; Graham RM; Kowala MC; Young MA, 1987, 'Altered Adrenergic Control in Hypercholesterolemia', Journal of Cardiovascular Pharmacology, 10, pp. S11 - S15, http://dx.doi.org/10.1097/00005344-198700109-00004
Journal articles | 1987
Ohanian J; Nicolosi RJ; Vatner SF; Graham RM; Kowala MC; Young MA, 1987, 'Altered adrenergic control in hypercholesterolemia', Journal of Cardiovascular Pharmacology, 10, pp. S11 - S15, http://dx.doi.org/10.1097/00005344-198706109-00004
Journal articles | 1987
Parini A; Homcy CJ; Graham RM, 1987, 'Structural properties of the alpha 1-adrenergic receptor: studies with membrane and purified receptor preparations.', Circulation research, 61
Sawutz DG; Lanier SM; Warren CD; Graham RM, 1987, 'Glycosylation of the mammalian α1-adrenergic receptor by complex type N-linked oligosaccharides', Molecular Pharmacology, 32, pp. 565 - 571
Journal articles | 1987
Sawutz DG; Sena LM; Cornett LE; Graham RM, 1987, 'Alpha1-adrenergic receptor photoaffinity labeling in intact cells', Biochemical Pharmacology, 36, pp. 4027 - 4032, http://dx.doi.org/10.1016/0006-2952(87)90477-1
Journal articles | 1987
Wildey GM; Fischman AJ; Graham RM, 1987, 'Molecular and cellular biology of atrial natriuretic factor biosynthesis and secretion', Current Opinion in Cardiology, 2, pp. 647 - 652, http://dx.doi.org/10.1097/00001573-198707000-00012
Journal articles | 1987
Zisfein JB; Graham RM; Dreskin SV; Wildey GM; Fischman AJ; Homcy CJ, 1987, 'Characterization and Purification of a Protease in Serum That Cleaves Proatrial Natriuretic Factor (ProANF) to Its Circulating Forms', Biochemistry, 26, pp. 8690 - 8697, http://dx.doi.org/10.1021/bi00400a030
Journal articles | 1987
Zisfein JB; Sylvestre D; Homcy CJ; Graham RM, 1987, 'Analysis of atrial natriuretic factor biosynthesis and secretion in adult and neonatal rat atrial cardiocytes', Life Sciences, 41, pp. 1953 - 1959, http://dx.doi.org/10.1016/0024-3205(87)90748-X
Journal articles | 1986
Corvera S; Schwarz KR; Graham RM; Garcia-Sainz JA, 1986, 'Phorbol esters inhibit α1-adrenergic effects and decrease the affinity of liver cell α1-adrenergic receptors for (-)-epinephrine', Journal of Biological Chemistry, 261, pp. 520 - 526
Journal articles | 1986
Dimsdale JE; Pierce C; Schoenfeld D; Brown A; Zusman R; Graham R, 1986, 'Suppressed anger and blood pressure: The effects of race, sex, social class, obesity, and age', Psychosomatic Medicine, 48, pp. 430 - 436, http://dx.doi.org/10.1097/00006842-198607000-00005
Journal articles | 1986
Graham RM; Bloch KD; Delaney VB; Bourke E; Seidman JG, 1986, 'Bartter's syndrome and the atrial natriuretic factor gene', Hypertension, 8, pp. 549 - 551, http://dx.doi.org/10.1161/01.HYP.8.6.549
Journal articles | 1986
JAMES MP; GRAHAM RM; ENGLISH J, 1986, 'Percutaneous iontophoresis of prednisolone–a pharmacokinetic study', Clinical and Experimental Dermatology, 11, pp. 54 - 61, http://dx.doi.org/10.1111/j.1365-2230.1986.tb00424.x
Lanier SM; Graham RM; Hess HJ; Grodski A; Repaske MG; Nunnari JM; Limbird LE; Homcy CJ, 1986, 'Photoaffinity labeling of the porcine brain α2-adrenergic receptor using a radioiodinated arylazide derivative of rauwolscine: Identification of the hormone-binding subunit', Proceedings of the National Academy of Sciences of the United States of America, 83, pp. 9358 - 9362, http://dx.doi.org/10.1073/pnas.83.24.9358
Journal articles | 1986
Lanier SM; Hess HJ; Grodski A; Graham RM; Homcy CJ, 1986, 'Synthesis and characterization of a high affinity radioiodinated probe for the α-2-adrenergic receptor', Molecular Pharmacology, 29, pp. 219 - 227
Journal articles | 1986
Longabaugh JP; Vatner DE; Graham RM; Momcy CJ, 1986, 'NADP improves the efficiency of cholera toxin gatalyzed ADP-ribosylation in liver and heart membranes', Biochemical and Biophysical Research Communications, 137, pp. 328 - 333, http://dx.doi.org/10.1016/0006-291X(86)91214-3
Journal articles | 1986
Schwarz KR; Carter EA; Homcy CJ; Graham RM, 1986, 'Agonist Interactions at Hepatic α1- and β-Adrenergic Receptors: Affinity-State Regulation by Guanine Nucleotides and Temperature', Biochemistry, 25, pp. 7782 - 7788, http://dx.doi.org/10.1021/bi00371a074
Journal articles | 1986
Schwarz KR; Lanier SM; Sena LM; Carter EA; Graham RM; Homcy CJ, 1986, 'Agonist-Induced Isomerization of the α1-Adrenergic Receptor: Kinetic Analysis Using Broken-Cell and Solubilized Preparations', Biochemistry, 25, pp. 2697 - 2702, http://dx.doi.org/10.1021/bi00357a062
Journal articles | 1986
Sylvestre DL; Zisfein JB; Graham RM; Homcy CJ, 1986, 'Serum-mediated enhancement of ANF accumulation in the culture medium of cardiac atriocytes', Biochemical and Biophysical Research Communications, 140, pp. 151 - 159, http://dx.doi.org/10.1016/0006-291X(86)91070-3
Journal articles | 1986
VERBOV J; GRAHAM R, 1986, 'Buschke‐Ollendorff syndrome–disseminated dermatofibrosis with osteopoikilosis', Clinical and Experimental Dermatology, 11, pp. 17 - 26, http://dx.doi.org/10.1111/j.1365-2230.1986.tb00419.x
Journal articles | 1986
Zisfein JB; Matsueda GR; Fallon JT; Bloch KD; Seidman CE; Seidman JG; Homcy CJ; Graham RM, 1986, 'Atrial natriuretic factor: Assessment of its structure in atria and regulation of its biosynthesis with volume depletion', Journal of Molecular and Cellular Cardiology, 18, pp. 917 - 929, http://dx.doi.org/10.1016/S0022-2828(86)80006-2
Journal articles | 1985
Anderson S; Graham RM; Brater DC, 1985, 'Differences in response of black hypertensives to alpha vs. beta adrenergic antagonists: Preliminary findings', American Journal of the Medical Sciences, 290, pp. 15 - 18, http://dx.doi.org/10.1097/00000441-198507000-00004
Journal articles | 1985
Bloch KD; Scott JA; Zisfein JB; Fallon JT; Margolies MN; Seidman CE; Matsueda GR; Homcy CJ; Graham RM; Seidman JG, 1985, 'Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes', Science, 230, pp. 1168 - 1171, http://dx.doi.org/10.1126/science.2933808
GRAHAM RM; JAMES MP; FERGUSON DJP; GUERRIER CW, 1985, 'Acquired kinking of the hair associated with etretinate therapy', Clinical and Experimental Dermatology, 10, pp. 426 - 431, http://dx.doi.org/10.1111/j.1365-2230.1985.tb00599.x
Journal articles | 1985
GRAHAM RM; MCKEE PH; CHAPMAN DV; RICHARDSON TC; STOKOE MR; HEYDERMAN E, 1985, 'Intercellular canaliculi in eccrine sweat glands: an immunoperoxidase study', British Journal of Dermatology, 112, pp. 397 - 403, http://dx.doi.org/10.1111/j.1365-2133.1985.tb02312.x
Graham RM; James MP; Bennett S, 1985, 'Low concentration zinc sulphate solution in the management of recurrent herpes simplex infection', British Journal of Dermatology, 112, pp. 123 - 124, http://dx.doi.org/10.1111/j.1365-2133.1985.tb02303.x
Graham RM; James MP, 1985, 'Pseudo-ainhum, angiodysplasia and focal acral hyperkeratosis', Journal of the Royal Society of Medicine, 78, pp. 13 - 15
Journal articles | 1985
Homcy C; Gaivin R; Zisfein J; Graham RM, 1985, 'Snack-Induced Release of Atrial Natriuretic Factor', New England Journal of Medicine, 313, pp. 1484, http://dx.doi.org/10.1056/NEJM198512053132323
Lanier SM; Graham RM; Hess HJ, 1985, 'Synthesis and characterization of a novel radioiodinated probe for the alpha-2 adrenergic receptor', Federation Proceedings, 44
Journal articles | 1985
Lewis SF; Snell PG; Taylor WF; Hamra M; Graham RM; Pettinger WA; Blomqvist CG, 1985, 'Role of muscle mass and mode of contraction in circulatory responses to exercise', Journal of Applied Physiology, 58, pp. 146 - 151, http://dx.doi.org/10.1152/jappl.1985.58.1.146
Journal articles | 1985
Mulvihill-Wilson J; Gaffney FA; Neal WW; Graham RM; Pettinger WA; Blomqvist CG, 1985, 'Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: Hemodynamic and neuroendocrine mechanisms of action', The American Journal of Cardiology, 56, pp. 315 - 320, http://dx.doi.org/10.1016/0002-9149(85)90856-2
Journal articles | 1985
NEWTON JA; CAMPLEJOHN RS; BOWYER C; GRAHAM RM; McGIBBON DM; WRIGHT NA, 1985, 'Clinical signs of response to treatment in psoriasis–a cell kinetic and histological assessment using the IBAS II image analyser', Clinical and Experimental Dermatology, 10, pp. 36 - 40, http://dx.doi.org/10.1111/j.1365-2230.1985.tb02549.x
Journal articles | 1985
Schwarz KR; Carter EA; Homcy CJ; Graham RM, 1985, 'Regulation of adrenergic agonist affinity states', Federation Proceedings, 44
Journal articles | 1985
Schwarz KR; Lanier SM; Carter EA; Graham RM; Homey CJ, 1985, 'Transient high-affinity binding of agonists to α1-adrenergic receptors of intact liver cells', FEBS Letters, 187, pp. 205 - 210, http://dx.doi.org/10.1016/0014-5793(85)81243-6
Journal articles | 1985
Schwarz KR; Lanier SM; Carter EA; Homcy CJ; Graham RM, 1985, 'Rapid reciprocal changes in adrenergic receptors in intact isolated hepatocytes during primary cell culture', Molecular Pharmacology, 27, pp. 200 - 209
Journal articles | 1985
Seidman CE; Bloch KD; Zisfein J; Smith JA; Haber E; Homcy C; Duby AD; Choi E; Graham RM; Seidman JG, 1985, 'Molecular studies of the atrial natriuretic factor gene', Hypertension, 7, pp. 31 - 34, http://dx.doi.org/10.1161/01.hyp.7.3_pt_2.i31
Journal articles | 1984
Bartzokas CA; Paton JH; Gibson MF; Graham R; Mcloughlin GA; Croton RS, 1984, 'Control and Eradication of Methicillin-Resistant Staphylococcus aureus on a Surgical Unit', New England Journal of Medicine, 311, pp. 1422 - 1425, http://dx.doi.org/10.1056/NEJM198411293112207
Journal articles | 1984
Fitzgibbon EJ; Bartzokas CA; Martin MV; Gibson MF; Graham R, 1984, 'The source, frequency and extent of bacterial contamination of dental unit water systems', British Dental Journal, 157, pp. 98 - 101, http://dx.doi.org/10.1038/sj.bdj.4805436
Graham RM; James MP, 1984, 'Epithelioid sarcoma of Enzinger', Journal of the Royal Society of Medicine, 77, pp. 24 - 26
Journal articles | 1984
Graham RM, 1984, 'Selective alpha1-adrenergic antagonists: Therapeutically relevant antihypertensive agents', The American Journal of Cardiology, 53, http://dx.doi.org/10.1016/0002-9149(84)90829-4
Journal articles | 1984
HEYDERMAN E; GRAHAM RM; CHAPMAN DV; RICHARDSON TC; McKEE PH, 1984, 'Epithelial markers in primary skin cancer: an immunoperoxidase study of the distribution of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in 65 primary skin carcinomas', Histopathology, 8, pp. 423 - 434, http://dx.doi.org/10.1111/j.1365-2559.1984.tb02354.x
Journal articles | 1984
Haber E; Dzau VJ; Graham RM; Zusman RM, 1984, 'Hypertension: The evolution of a scientific journal', Hypertension, 6, pp. 1
Journal articles | 1984
Schwarz K; Carter E; Graham R; Homcy C, 1984, 'Rapid reciprocal changes in alpha (a1R) and beta (bR) adrenergic receptor number during primary cell culture of isolated hepatocytes (IHC)', Federation Proceedings, 43
Journal articles | 1984
Seidman CE; Duby AD; Choi E; Graham RM; Haber E; Homcy C; Smith JA; Seidman JG, 1984, 'The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone', Science, 225, pp. 324 - 326, http://dx.doi.org/10.1126/science.6234658
Journal articles | 1984
Seidman CE; Hess HJ; Homcy CJ; Graham RM, 1984, 'Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha1-adrenergic receptor', Hypertension, 6, pp. I-7-I-11, http://dx.doi.org/10.1161/01.hyp.6.2_pt_2.i7
Journal articles | 1984
Seidman CE; Homey CJ; Graham RM; Hess HJ, 1984, 'Photoaffinity Labeling of the α1-Adrenergic Receptor Using an 125I-Labeled Aryl Azide Analogue of Prazosin', Biochemistry, 23, pp. 3765 - 3770, http://dx.doi.org/10.1021/bi00311a031
Journal articles | 1983
Andrew Gaffney F; Bastian BC; Lane LB; Fred Taylor W; Horton J; Schutte JE; Graham RM; Pettinger W; Gunnar Blomqvist C, 1983, 'Abnormal cardiovascular regulation in the mitral valve prolapse syndrome', The American Journal of Cardiology, 52, pp. 316 - 320, http://dx.doi.org/10.1016/0002-9149(83)90130-3
Journal articles | 1983
Bartzokas CA; Gibson MF; Graham R; Pinder DC, 1983, 'A comparison of triclosan and chlorhexidine preparations with 60 per cent isopropyl alcohol for hygienic hand disinfection', Journal of Hospital Infection, 4, pp. 245 - 255, http://dx.doi.org/10.1016/0195-6701(83)90025-7
Graham RM, 1983, 'Considerations in the long-term treatment of hypertension', Clinical Therapeutics, 5, pp. 224 - 233
Journal articles | 1983
Hess HJ; Graham RM; Homcy CJ, 1983, 'Photoaffinity label for the α1-adrenergic receptor: Synthesis and effects on membrane and affinity-purified receptors', Proceedings of the National Academy of Sciences of the United States of America, 80, pp. 2102 - 2106, http://dx.doi.org/10.1073/pnas.80.8.2102
Journal articles | 1983
Lewis SF; Taylor WF; Bastian BC; Graham RM; Pettinger WA; Blomqvist CG, 1983, 'Haemodynamic responses to static and dynamic handgrip before and after autonomic blockade', Clinical Science, 64, pp. 593 - 599, http://dx.doi.org/10.1042/cs0640593
Journal articles | 1983
Lewis SF; Taylor WF; Graham RM; Pettinger WA; Schutte JE; Blomqvist CG, 1983, 'Cardiovascular responses to exercise as functions of absolute and relative work load', Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, 54, pp. 1314 - 1323, http://dx.doi.org/10.1152/jappl.1983.54.5.1314
Journal articles | 1983
Mulvihill-Wilson J; Gaffney FA; Pettinger WA; Blomqvist CG; Anderson S; Graham RM, 1983, 'Hemodynamic and neuroendocrine responses to acute and chronic alpha-adrenergic blockade with prazosin and phenoxybenzamine', Circulation, 67, pp. 383 - 393, http://dx.doi.org/10.1161/01.CIR.67.2.383
Journal articles | 1982
Graham RM; Campbell WB; Jackson EK, 1982, 'Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2α in normal subjects', Clinical Pharmacology and Therapeutics, 31, pp. 324 - 329, http://dx.doi.org/10.1038/clpt.1982.41
Journal articles | 1982
Graham RM; Hess HJ; Haber E; Homcy CJ, 1982, 'Antibodies to the alpha1- and alpha2-selective antagonists prazosin and yohimbine as probes of the alpha-adrenergic binding sites', Hypertension, 4, pp. 183 - 187, http://dx.doi.org/10.1161/01.HYP.4.3.183
Journal articles | 1982
Graham RM; Hess HJ; Haber E; Homcy CJ, 1982, 'Antibodies to the alpha1- and alpha2-selective antagonists prazosin and yohimbine as probes of the alpha-adrenergic binding sites', Hypertension, 4, pp. 183 - 187, http://dx.doi.org/10.1161/01.HYP.4.3.183
Journal articles | 1982
Graham RM; Hess HJ; Homcy CJ, 1982, 'Biophysical characterization of the purified α1-adrenergic receptor and identification of the hormone binding subunit', Journal of Biological Chemistry, 257, pp. 15174 - 15181
Journal articles | 1982
Graham RM; Hess HJ; Homcy CJ, 1982, 'Solubilization and purification of the α1-adrenergic receptor using a novel affinity resin', Proceedings of the National Academy of Sciences of the United States of America, 79, pp. 2186 - 2190, http://dx.doi.org/10.1073/pnas.79.7.2186
Journal articles | 1982
Graham RM; Pettinger WA; Sagalowsky A; Brabson J; Gandler T, 1982, 'Renal alpha-adrenergic receptor abnormality in the spontaneously hypertensive rat', Hypertension, 4, pp. 881 - 887, http://dx.doi.org/10.1161/01.HYP.4.6.881
Journal articles | 1982
Hess HJ; Graham RM; Homcy CJ, 1982, 'Photoaffinity label of the α1-adrenergic receptor (α1AR): Synthesis and effects on rat hepatic membrane (M) and affinity purified (P) receptors', Federation Proceedings, 41
Journal articles | 1982
Homcy CJ; Graham RM; Haber E; Hess HJ, 1982, 'Characterization of the purified mammalian α- and β-adrenergic receptors reveals homologous molecular properties', Clinical Research, 30
Journal articles | 1982
Homey C; Sylvestre D; Graham R, 1982, 'Solubilization and characterization of the mammalian β2-receptor (βR) in 8M urea', Federation Proceedings, 41, pp. 6774
Journal articles | 1981
Blomqvist CG; Lewis SF; Taylor WF; Graham RM, 1981, 'Similarity of the hemodynamic responses to static and dynamic exercise of small muscle groups', Circulation Research, 48
Journal articles | 1981
Campbell WB; Callahan KS; Johnson AR; Graham RM, 1981, 'ANTI-PLATELET ACTIVITY OF BETA-ADRENERGIC ANTAGONISTS: INHIBITION OF THROMBOXANE SYNTHESIS AND PLATELET AGGREGATION IN PATIENTS RECEIVING LONG-TERM PROPRANOLOL TREATMENT', The Lancet, 318, pp. 1382 - 1384, http://dx.doi.org/10.1016/S0140-6736(81)92800-2
Journal articles | 1981
Campbell WB; Holland OB; Gomez-Sanchez CE; Graham RM; Pettinger WA; White AC, 1981, 'Plasma substance p levels in normotensive and hypertensive subjects', Clinical and Experimental Hypertension, 3, pp. 183 - 193, http://dx.doi.org/10.3109/10641968109033659
Journal articles | 1981
Graham RM; Campbell WB, 1981, 'Speculative approaches in hypertension: Concepts and drugs of the future', Federation Proceedings, 40, pp. 2291 - 2295
Journal articles | 1981
Graham RM; Hess HJ; Homcy C, 1981, 'Solubilization and purification of α-adrenergic receptors utilizing a novel affinity technique', Federation Proceedings, 40, pp. 1630
Journal articles | 1981
Schmitz JM; Graham RM; Sagalowsky A; Pettinger WA, 1981, 'Renal alpha-1 and alpha-2 adrenergic receptors: Biochemical and pharmacological correlations', Journal of Pharmacology and Experimental Therapeutics, 219, pp. 400 - 406
Journal articles | 1980
Boyar RM; Fixler DF; Kaplan NM; Graham RM; Price KP; Chipman JJ; Pennock Laird W, 1980, 'Effects of clonidine on 24-hour hormonal secretory patterns, cardiovascular hemodynamics, and central nervous function in hypertensive adolescents', Hypertension, 2, pp. 83 - 89, http://dx.doi.org/10.1161/01.HYP.2.1.83
Journal articles | 1980
CAMPBELL WB; GRAHAM RM; JACKSON EK; LOISEL DP; PETTINGER WA, 1980, 'EFFECT OF INDOMETHACIN ON HYDRALAZINE‐INDUCED RENIN AND CATECHOLAMINE RELEASE IN THE CONSCIOUS RABBIT', British Journal of Pharmacology, 71, pp. 529 - 531, http://dx.doi.org/10.1111/j.1476-5381.1980.tb10968.x
Journal articles | 1980
Campbell WB; Graham RM; Jackson EK, 1980, 'Inhibition of hydralazine-induced renin release by indomethacin in the rat', Archives Internationales de Pharmacodynamie et de Therapie, 246, pp. 315 - 323
Journal articles | 1980
Graham RM; Mulvihill-Wilson J, 1980, 'Clinical pharmacology of prazosin used alone or in combination in the therapy of hypertension', Journal of Cardiovascular Pharmacology, 2, http://dx.doi.org/10.1097/00005344-198002003-00012
Journal articles | 1980
Graham RM; Stephenson WH; Pettinger WA, 1980, 'Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat', Naunyn-Schmiedeberg's Archives of Pharmacology, 311, pp. 129 - 138, http://dx.doi.org/10.1007/BF00510251
Journal articles | 1980
Mitchell HC; Graham RM; Pettinger WA, 1980, 'Renal function during long-term treatment of hypertension with minoxidil. Comparison of benign and malignant hypertension', Annals of Internal Medicine, 93, pp. 676 - 681, http://dx.doi.org/10.7326/0003-4819-93-5-676
Journal articles | 1980
Mukherjee A; Graham RM; Sagalowsky AI; Pettinger W; McCoy KE, 1980, 'Myocardial beta-adrenergic receptors in the stroke-prone spontaneously hypertensive rat', Journal of Molecular and Cellular Cardiology, 12, pp. 1263 - 1272, http://dx.doi.org/10.1016/0022-2828(80)90070-X
Journal articles | 1980
Mulvihill-Wilson J; Graham RM; Pettttinger WA; Muckleroy C; Anderson S; Gaffney F; Blomqvist CG, 1980, 'Comparación de los efectos de prazosin y fenoxibenzamina sobre presión arterial, frecuencia cardiaca y catecolaminas plasmáticas en la hipertensión arterial esencial', Cardiology (Switzerland), 66, pp. 85 - 93, http://dx.doi.org/10.1159/000173013
Journal articles | 1979
Campbell WB; Graham RM; Jackson EK, 1979, 'Role of renal prostaglandins in sympathetically mediated renin release in the rat', Journal of Clinical Investigation, 64, pp. 448 - 456, http://dx.doi.org/10.1172/JCI109482
Journal articles | 1979
Campbell WB; Jackson EK; Graham RM, 1979, 'Saralasin-induced renin release: Blockade by prostaglandin synthesis inhibitors', Federation Proceedings, 38
Journal articles | 1979
Campbell WB; Jackson EK; Graham RM, 1979, 'Saralasin-induced renin release: Its blockade by prostaglandin synthesis inhibitors in the conscious rat', Hypertension, 1, pp. 637 - 642, http://dx.doi.org/10.1161/01.HYP.1.6.637
Journal articles | 1979
Graham RM; Campbell WB; Jackson EK, 1979, 'Role of prostaglandins in hydralazine-induced renin and catecholamine release in conscious rabbits', Federation Proceedings, 38
Journal articles | 1979
Graham RM; Pettinger WA, 1979, 'Effects of prazosin and phentolamine on arterial pressure, heart rate, and renin activity: Evidence in the conscious rat for the functional significance of the presynaptic α-receptor', Journal of Cardiovascular Pharmacology, 1, pp. 497 - 502, http://dx.doi.org/10.1097/00005344-197909000-00002
Journal articles | 1979
Huysmans FTM; Thien T; Koene RAP; Graham RM; Pettinger WA, 1979, 'Hypotensive Action of Prazosin', New England Journal of Medicine, 300, pp. 1335 - 1336, http://dx.doi.org/10.1056/NEJM197906073002316
Mulvihill-Wilson J; Graham RM; Pettinger W; Muckleroy C; Anderson S; Andrew Gaffney F; Gunner Blomqvist C, 1979, 'Comparative effects of prazosin and phenoxybenzamine on arterial blood pressure, heart rate, and plasma catecholamines in essential hypertension', Journal of Cardiovascular Pharmacology, 1, pp. S1 - S7, http://dx.doi.org/10.1097/00005344-197900011-00001
Journal articles | 1979
Mulvihill-Wilson J; Graham RM; Pettinger W; Muckleroy C; Anderson S; Gaffney FA; Blomqvist CG, 1979, 'Comparative Effects of Prazosin and Phenoxybenzamine on Arterial Blood Pressure, Heart Rate, and Plasma Catecholamines in Essential Hypertension', Journal of Cardiovascular Pharmacology, 1, pp. S1 - 7, http://dx.doi.org/10.1097/00005344-197911001-00001
Journal articles | 1979
Mulvihill-Wilson JM; Graham RM; Pettinger WA, 1979, 'Role of selective blockade of α-adrenergic receptors in the antihypertensive effects of α-receptor antagonists in man', Clinical Research, 27
Journal articles | 1979
Sagalowsky AI; Graham RM; Schmitz JM; Pettinger WA, 1979, 'Comparison of pharmacologic and biochemical characteristics of renal alpha receptors', Clinical Research, 27
Journal articles | 1979
Stokes GS; Frost GW; Graham RM; MacCarthy EP, 1979, 'Indoramin and prazosin as adjuncts to beta-adrenoreceptor blockade in treatment of hypertension', Clinical and Experimental Pharmacology and Physiology, 6, pp. 669
Journal articles | 1979
Stokes GS; Frost GW; Graham RM; MacCarthy EP, 1979, 'Indorarnin and prazosin as adjuncts to beta adrenoceptor blockade in hypertension', Clinical Pharmacology and Therapeutics, 25, pp. 783 - 789, http://dx.doi.org/10.1002/cpt1979256783
Journal articles | 1978
Bartzokas CA; McCarthy K; Baker BF; Graham R, 1978, 'Observations of the effects of formaldehyde on cockroaches and their flora: III. The effect of formaldehyde in eliminating the normal gut flora', Journal of Hygiene, 80, pp. 137 - 141, http://dx.doi.org/10.1017/S0022172400053468
Journal articles | 1978
Graham RM; Brabson JH; Stephenson WH; Pettinger WA, 1978, 'Increased renal α-adrenergic receptors in genetically hypertensive rats', Clinical Research, 26
Journal articles | 1978
Graham RM; Brabson JH; Stephenson WH; Pettinger WA, 1978, 'Renal α-adrenergic receptors and hypertension', Circulation, 58
Journal articles | 1978
Graham RM; Kennedy P; Stephenson W; Pettinger WA, 1978, 'In vivo evidence for the presynaptic α-adrenergic receptor controlling norepinephrine release', Federation Proceedings, 37
Journal articles | 1978
Oates HF; Graham RM; Stokes GS, 1978, 'Contrasting actions of four peripherally acting antihypertensive drugs', Clinical and Experimental Pharmacology and Physiology, 5, pp. 244
Journal articles | 1977
Graham RM; Gain JMW; Stokes GS, 1977, 'The Use of Clonidine by Intramuscular Injection in the Treatment of Hypertension', Australian and New Zealand Journal of Medicine, 7, pp. 131 - 133, http://dx.doi.org/10.1111/j.1445-5994.1977.tb04678.x
Journal articles | 1977
Graham RM; Oates HF; Stoker LM; Stokes GS, 1977, 'Alpha blocking action of the antihypertensive agent, prazosin', Journal of Pharmacology and Experimental Therapeutics, 201, pp. 747 - 752
Journal articles | 1977
Oates HF; Graham RM; Stokes GS, 1977, 'Mechanism of the hypotensive action of prazosin', Archives Internationales de Pharmacodynamie et de Therapie, 227, pp. 41 - 48
Journal articles | 1977
Stokes GS; Graham RM; Gain JM; Davis PR, 1977, 'Influence of dosage and dietary sodium on the first-dose effects of prazosin', British Medical Journal, 1, pp. 1507 - 1508, http://dx.doi.org/10.1136/bmj.1.6075.1507
Journal articles | 1977
Weber MA; Graham RM; Gain JM; Stokes GS, 1977, 'Pharmacological stimulation of renin secretion within the kidney', Archives Internationales de Pharmacodynamie et de Therapie, 227, pp. 343 - 350
Journal articles | 1976
Graham RM; Muir MR; Hayes JM, 1976, 'DIFFERING EFFECTS OF THE VASODILATOR DRUGS, PRAZOSIN AND DIAZOXIDE ON PLASMA RENIN ACTIVITY IN THE DOG', Clinical and Experimental Pharmacology and Physiology, 3, pp. 173 - 177, http://dx.doi.org/10.1111/j.1440-1681.1976.tb00602.x
Journal articles | 1976
Graham RM; Oates HF; Weber MA; Stokes GS, 1976, 'Suppression of renin release by timolol', Archives Internationales de Pharmacodynamie et de Therapie, 219, pp. 205 - 210
Journal articles | 1976
Graham RM; Sebel EF; Stokes GS, 1976, 'Surgical intervention in severe and complicated renal hypertension: Report of the Sydney Renal Hypertension Group (1969-75)', Clinical Science and Molecular Medicine, 51, pp. 231 - 233
Journal articles | 1976
Graham RM; Thornell IR; Gain JM; Bagnoli C; Oates HF; Stokes GS, 1976, 'Prazosin: The first-dose phenomenon', British Medical Journal, 2, pp. 1293 - 1294, http://dx.doi.org/10.1136/bmj.2.6047.1293
Journal articles | 1976
Hayes JM; Graham RM; O'Connell BP; Muir MR; Speers E; Humphery TJ, 1976, 'Experience with prazosin in the treatment of patients with severe hypertension', Medical Journal of Australia, 1, pp. 562 - 564, http://dx.doi.org/10.5694/j.1326-5377.1976.tb140863.x
Journal articles | 1976
Oates HF; Graham RM; Stoker LM; Stokes GS, 1976, 'Haemodynamic efects of prazosin', Archives Internationales de Pharmacodynamie et de Therapie, 224, pp. 239 - 247
Journal articles | 1976
Stokes GS; Graham RM; Weber MA, 1976, 'The Role of Renin in the Antihypertensive Action of β-Adrenoreceptor Blocking Agents', Drugs, 11, pp. 150 - 156, http://dx.doi.org/10.2165/00003495-197600111-00031
Journal articles | 1975
Weber MA; Thornell IR; Graham RM; Stokes GS, 1975, 'Beta-adrenoreceptor blockade in the conscious rabbit: Effects on plasma renin activity and blood pressure', Life Sciences, 17, pp. 959 - 967, http://dx.doi.org/10.1016/0024-3205(75)90449-X
Journal articles | 1974
Hayes JM; Graham RM; O'Connell BP, 1974, 'Prazosin in hypertension', British Medical Journal, 4, pp. 108
Conference Papers | 2023
Ballinger ML; Pattnaik S; Mundra PA; Zaheed M; Rath E; Priestley P; Baber J; Ray-Coquard I; Isambert N; Causeret S; van der Graaf WTA; Puri A; Duffaud F; Le Cesne A; Seddon B; Chandrasekar C; Schiffman JD; Brohl AS; James PA; Kurtz JE; Penel N; Myklebost O; Meza-Zepeda LA; Pickett H; Kansara M; Waddell N; Kondrashova O; Pearson JV; Barbour AP; Li S; Nguyen TL; Fatkin D; Graham RM; Giannoulatou E; Green MJ; Kaplan W; Ravishankar S; Copty J; Powell JE; Cuppen E; van Eijk K; Veldink J; Ahn JH; Kim JE; Lor Randall R; Tucker K; Judson I; Sarin R; Ludwig T; Genin E; Deleuze JF; Haber M; Marshall G; Cairns MJ; Blay JY; Thomas DM, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', in Science, WILEY, pp. 253 - 260, http://dx.doi.org/10.1126/science.abj4784
Preprints | 2023
Murtha LA; Hardy SA; Mabotuwana NS; Bigland MJ; Bailey T; Raguram K; Liu S; Ngo DT; Sverdlov AL; Tomin T; Birner-Gruenberger R; Hume RD; Iismaa SE; Humphreys DT; Patrick R; Chong JJH; Lee RJ; Harvey RP; Graham RM; Rainer PP; Boyle AJ, 2023, Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction, , http://dx.doi.org/10.21203/rs.3.rs-3055737/v1
Conference Abstracts | 2022
Adiam D; Berrandou TE; Georges A; Nelson CP; Giannoulatou E; Ma L; Blencowe M; Turley T; Yang M-L; Iismaa S; Tarr I; Muller D; Hesselson S; Junday K; Fatkin D; Combaret N; Saw J; Webb T, 2022, 'GWAS Meta-Analysis in SCAD, a Women Predominant Ischemic Heart Disease, Reveals Common Variants and Genes Related to Artery Integrity and Tissue-Mediated Coagulation', in Circulation, Lippincott, Williams & Wilkins, IL, Chicago, Vol. 146, presented at Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, IL, Chicago, 05 November 2022 - 06 November 2022, https://www.ahajournals.org/doi/10.1161/circ.146.suppl_1.12681
Conference Abstracts | 2022
Yu Z-Y; Gong H; Kesteven S; Guo Y; Wu J; Li J; Iismaa S; Kaidonis X; Graham RM; Cox CD; Feneley MP; Martinac B, 2022, 'Piezo1 and TRPM4 work in tandem to initiate cardiac hypertrophic signalling in response to pressure overload', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 121, pp. 493A - 493A, http://dx.doi.org/10.1016/j.bpj.2021.11.321
Nicks A; Holman S; Chan A; Tsang M; Young P; Humphreys D; Naqvi N; Husain A; Li M; Smith N; Iismaa S; Graham R, 2021, Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts, , http://dx.doi.org/10.1101/2021.09.30.462562
Wu J; Nicks AM; Skowno JJ; Feneley MP; Iismaa SE; Graham RM, 2021, Anesthesia and Intubation of 10-Day Old C57BL/6J Mouse Pups for Cardiothoracic Surgery, , http://dx.doi.org/10.21203/rs.3.rs-1144085/v1
Preprints | 2021
Yu Z-Y; Gong H; Kesteven S; Guo Y; Wu J; Li J; Iismaa S; Kaidonis X; Graham R; Cox C; Feneley M; Martinac B, 2021, Piezo1 is the cardiac mechanosensor that initiates the hypertrophic response to pressure overload, , http://dx.doi.org/10.21203/rs.3.rs-895561/v1
Preprints | 2020
Bogush N; Tan L; Naib H; Faizullabhoy E; Calvert JW; Iismaa SE; Gupta A; Ramchandran R; Martin DIK; Graham RM; Husain A; Naqvi N, 2020, DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling, , http://dx.doi.org/10.21203/rs.3.rs-73803/v1
Preprints | 2020
Guo Y; Yu Z-Y; Wu J; Gong H; Kesteven S; Iismaa S; Chan A; Holman S; Pinto S; Pironet A; Cox C; Graham R; Vennekens R; Feneley M; Martinac B, 2020, The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy, , http://dx.doi.org/10.1101/2020.12.21.423727
Yu Z-Y; Gong H; Wu J; Dai Y; Kesteven SH; Fatkin D; Martinac B; Graham RM; Feneley MP, 2020, Cardiac Gq receptors and calcineurin activation are not required for the hypertrophic response to mechanical left ventricular pressure overload, , http://dx.doi.org/10.1101/2020.12.08.393595
Mouat M; Coleman J; Wu J; Jancovski N; Feneley M; Allen A; Graham R; Smith N, 2018, 'SEXUALLY DIMORPHIC ROLES FOR GPR37L1, AN ORPHAN GPCR IN THE CARDIOVASCULAR SYSTEM', in JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, PEOPLES R CHINA, Beijing, pp. E7 - E7, presented at 27th Scientific Meeting of the International-Society-of-Hypertension, PEOPLES R CHINA, Beijing, 20 September 2018 - 23 September 2018, http://dx.doi.org/10.1097/01.hjh.0000548013.63617.a8
Jabbour A; Gao L; Kwan J; Watson A; Liu X; Zhou MD; Graham RM; Hicks M; Macdonald PS, 2009, 'A Recombinant Human Neuregulin-1 Peptide Added to Celsior Solution Further Improves Preservation of the Transplanted Rat Heart after Prolonged Hypothermic Storage', in JOURNAL OF HEART AND LUNG TRANSPLANTATION, ELSEVIER SCIENCE INC, FRANCE, Paris, pp. S150 - S150, presented at 29th Annual Meeting and Scientific Session of the International-Society-for-Heart-and-Lung-Transplantation, FRANCE, Paris, 22 April 2009 - 25 April 2009, http://dx.doi.org/10.1016/j.healun.2008.11.869
Conference Papers | 2009
Jabbour A; Gao L; Kwan JC; Watson AS; Liu X; Zhou M; Graham RM; Hicks M; Macdonald PS, 2009, 'A Recombinant Human Neuregulin-1 Peptide Added to Celsior Solution Further Improves Preservation of the Transplanted Rat Heart after Prolonged Hypothermic Storage', in Journal of Heart and Lung Transplantation, Elsevier Science Inc, New York, NY, USA, pp. 238 - 239
Tatsukawa H; Tukamoto H; Shimokado K; Zern M; Graham RM; Kojima S, 2008, 'A NOVEL HEPATIC APOPTOSIS PATHWAY IN THE INJURED LIVER VIA CROSSLINKING AND INACTIVATION OF TRANSCRIPTION FACTOR, SP1 BY TISSUE TRANSGLUTAMINASE', in Hepatology, John Wiley & Sons Inc, Hoboken, NJ, USA, pp. 389 - 390, presented at Hepatology
Kovacic JC; Macdonald PS; Feneley MP; Muller DW; Ma DD; Tao H; Freund J; Milliken ST; Dodds AJ; Moore JJ; Itescu S; Graham RM, 2007, 'The use of granulocyte-colony stimulating factor in angina patients to stimulate neovascularization: the GAIN I study', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 2669 - 2670, presented at 80th Annual Scientific Session of the American-Heart-Association, Orlando, Florida, USA, 04 November 2007 - 07 November 2007
Graham RA; Martin M; Thadhani NN; Morosin B, 2006, 'Quartz and hydrous iron oxides from the bee bluff structure of South Texas', in AIP Conference Proceedings, pp. 1468 - 1471, http://dx.doi.org/10.1063/1.2263601
Conference Papers | 2006
Graham RA, 2006, 'Ballography: A billion nanosecond history of the bee bluff impact crater of South Texas', in AIP Conference Proceedings, pp. 1462 - 1467, http://dx.doi.org/10.1063/1.2263600
Weinstein RS; Bhattacharyya A; Yu YP; Davis JR; Byers JM; Graham R; Martinez R, 1995, 'Pathology consultation services via the Arizona-International Telemedicine Network', in Archives d'Anatomie et de Cytologie Pathologiques, pp. 219 - 226
Conference Papers | 1988
Braiman M; Bubis J; Doi T; Chen HB; Flitsch SL; Franke RR; Gilles-Gonzalez MA; Graham RM; Karnik SS; Khorana HG; Knox BE; Krebs MP; Marti T; Mogi T; Nakayama T; Oprian DD; Puckett KL; Sakmar TP; Stern LJ, 1988, 'Studies on light transduction by bacteriorhodopsin and rhodopsin', in Cold Spring Harbor Symposia on Quantitative Biology, pp. 355 - 364, http://dx.doi.org/10.1101/sqb.1988.053.01.043