Dr Rodrigo Curvello

Dr Rodrigo Curvello

Lecturer

PhD in Biomedical Engineering, Monash University, Australia

Bachelor of Biomedical Engineering, Federal University of ABC, Brazil, with Honours equivalent program at the Australian Regenerative Medicine Institute 

Bachelor of Science and Technology, Federal University of ABC, Brazil

Engineering
Biomedical Engineering

Dr Rodrigo Curvello is a Lecturer in the School of Biomedical Engineering at UNSW Sydney. He completed his PhD in Biomedical Engineering at the Bioresource Processing Institute of Australia (BioPRIA), Monash University, where he was awarded the Mollie Holman Medal for the best doctoral thesis in the Faculty of Engineering.

He completed postdoctoral research in tumour tissue engineering at Monash, including specialised training in pancreatic cancer at the Cold Spring Harbor Laboratory (USA), and in biomaterials at the Leibniz Institute of Polymer Research Dresden (Germany). Rodrigo holds a double degree in Biomedical Engineering and Science & Technology from the Federal University of ABC (Brazil), alongside an Honours-equivalent research program at the Australian Regenerative Medicine Institute.

At the intersection of tissue engineering and cancer biology, his research investigates how the tumour microenvironment shapes responses to targeted therapies. By combining biomaterial-based platforms, multicellular systems, organoids, and multiomics, Rodrigo engineers advanced, physiologically-relevant 3D models of human tumours "on a dish".

 

 

Location
Room 516, Level 5, Samuels Building
  • Book Chapters | 2022
    Curvello R; Loessner D, 2022, 'Mimicking Multicellular Features of the Tumor Microenvironment', in Biomaterial Based Approaches to Study the Tumour Microenvironment, The Royal Society of Chemistry, pp. 141 - 162, http://dx.doi.org/10.1039/9781839166013-00141
  • Journal articles | 2026
    Curvello R; Hauser S; Seifert M; Barlow CK; Steele JR; Salisbury E; Croagh D; Stok KS; Taubenberger AV; Schittenhelm RB; Loessner D, 2026, 'GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer', Advanced Science, 13, http://dx.doi.org/10.1002/advs.202516578
    Journal articles | 2026
    Jeevanandan SP; Reidy E; Clegg J; Curvello R; Ryan AE; Loessner D, 2026, 'Advanced 3D cancer models for analyzing tumor-immune cell interaction and therapeutic response', Molecular Cancer, 25, http://dx.doi.org/10.1186/s12943-026-02681-y
    Journal articles | 2026
    Peerani E; Candido JB; Maniati E; Tomás-Bort E; Sharma S; Clegg J; Kocher HM; Wang J; Curvello R; Loessner D, 2026, 'Matrix stiffness shapes transcriptional profiles and drug responses of pancreatic cancer cells', Acta Biomaterialia, 210, pp. 67 - 81, http://dx.doi.org/10.1016/j.actbio.2025.12.020
    Journal articles | 2025
    Clegg J; Curvello R; Gabrielyan A; Croagh D; Hauser S; Loessner D, 2025, 'Tailoring metabolic activity assays for tumour-engineered 3D models', Biomaterials Advances, 167, http://dx.doi.org/10.1016/j.bioadv.2024.214116
    Journal articles | 2024
    Curvello R; Berndt N; Hauser S; Loessner D, 2024, 'Recreating metabolic interactions of the tumour microenvironment', Trends in Endocrinology and Metabolism, 35, pp. 518 - 532, http://dx.doi.org/10.1016/j.tem.2023.12.005
    Journal articles | 2024
    Curvello R; Raghuwanshi VS; Wu CM; Mata J; Garnier G, 2024, 'Nano- and Microstructures of Collagen-Nanocellulose Hydrogels as Engineered Extracellular Matrices', ACS Applied Materials and Interfaces, 16, pp. 1370 - 1379, http://dx.doi.org/10.1021/acsami.3c10353
    Journal articles | 2023
    Curvello R; Kast V; Ordóñez-Morán P; Mata A; Loessner D, 2023, 'Biomaterial-based platforms for tumour tissue engineering', Nature Reviews Materials, 8, pp. 314 - 330, http://dx.doi.org/10.1038/s41578-023-00535-3
    Journal articles | 2021
    Curvello R; Alves D; Abud HE; Garnier G, 2021, 'A thermo-responsive collagen-nanocellulose hydrogel for the growth of intestinal organoids', Materials Science and Engineering C, 124, http://dx.doi.org/10.1016/j.msec.2021.112051
    Journal articles | 2021
    Curvello R; Garnier G, 2021, 'Cationic Cross-Linked Nanocellulose-Based Matrices for the Growth and Recovery of Intestinal Organoids', Biomacromolecules, 22, pp. 701 - 709, http://dx.doi.org/10.1021/acs.biomac.0c01510
    Journal articles | 2021
    Curvello R; Kast V; Abuwarwar MH; Fletcher AL; Garnier G; Loessner D, 2021, '3D Collagen-Nanocellulose Matrices Model the Tumour Microenvironment of Pancreatic Cancer', Frontiers in Digital Health, 3, http://dx.doi.org/10.3389/fdgth.2021.704584
    Journal articles | 2021
    Curvello R; Kast V; Loessner D, 2021, 'Abstract PO-069: Modeling the tumor microenvironment using tissue engineering technologies', Cancer Research, 81, http://dx.doi.org/10.1158/1538-7445.panca21-po-069
    Journal articles | 2021
    Curvello R; Kerr G; Micati DJ; Chan WH; Raghuwanshi VS; Rosenbluh J; Abud HE; Garnier G, 2021, 'Engineered Plant-Based Nanocellulose Hydrogel for Small Intestinal Organoid Growth', Advanced Science, 8, http://dx.doi.org/10.1002/advs.202002135
    Journal articles | 2021
    Mettu S; Hathi Z; Athukoralalage S; Priya A; Lam TN; Ong KL; Choudhury NR; Dutta NK; Curvello R; Garnier G; Lin CSK, 2021, 'Perspective on Constructing Cellulose-Hydrogel-Based Gut-Like Bioreactors for Growth and Delivery of Multiple-Strain Probiotic Bacteria', Journal of Agricultural and Food Chemistry, 69, pp. 4946 - 4959, http://dx.doi.org/10.1021/acs.jafc.1c00468
    Journal articles | 2020
    Alves D; Curvello R; Henderson E; Kesarwani V; Walker JA; Leguizamon SC; McLiesh H; Raghuwanshi VS; Samadian H; Wood EM; McQuilten ZK; Graham M; Wieringa M; Korman TM; Scott TF; Banaszak Holl MM; Garnier G; Corrie SR, 2020, 'Rapid Gel Card Agglutination Assays for Serological Analysis Following SARS-CoV-2 Infection in Humans', ACS Sensors, 5, pp. 2596 - 2603, http://dx.doi.org/10.1021/acssensors.0c01050
    Journal articles | 2019
    Curvello R; Mendoza L; McLiesh H; Manolios J; Tabor RF; Garnier G, 2019, 'Nanocellulose Hydrogel for Blood Typing Tests', ACS Applied Bio Materials, 2, pp. 2355 - 2364, http://dx.doi.org/10.1021/acsabm.9b00080
    Journal articles | 2019
    Curvello R; Raghuwanshi VS; Garnier G, 2019, 'Engineering nanocellulose hydrogels for biomedical applications', Advances in Colloid and Interface Science, 267, pp. 47 - 61, http://dx.doi.org/10.1016/j.cis.2019.03.002
    Journal articles | 2019
    Manderson CA; McLiesh H; Curvello R; Tabor RF; Manolios J; Garnier G, 2019, 'Photothermal incubation of red blood cells by laser for rapid pre-transfusion blood group typing', Scientific Reports, 9, pp. 11221, http://dx.doi.org/10.1038/s41598-019-47646-y
  • Conference Papers | 2025
    Curvello R; Hauser S; Salisbury E; Seifert M; Stok K; Taubenberger A; Loessner D, 2025, 'GOT1 inhibition drives remodeling of the extracellular matrix in pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, pp. B12 - B12, http://dx.doi.org/10.1158/1538-7445.PANCREATIC25-B012
    Conference Papers | 2022
    Curvello R; Kast V; Garnier G; Loessner D, 2022, 'COLLAGEN-NANOCELLULOSE FORMS A MATRIX OF CONTROLLABLE STIFFNESS TO MIMIC THE PANCREATIC TUMOUR MICROENVIRONMENT', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, POLAND, Krakow, pp. 149 - 150, presented at Tissue Engineering and Regenerative Medicine International Society (TERMIS), POLAND, Krakow, 28 June 2022 - 01 July 2022
    Conference Papers | 2022
    Curvello R; Raghuwanshi VS; Garnier G, 2022, 'Engineering Nanocellulose-based Matrices for 3D Cell Cultures', in Trans. of the XVIIth Fund. Res. Symp. Cambridge, 2022, Pulp & Paper Fundamental Research Committee (FRC), Manchester, pp. 291 - 305, presented at Advances in Pulp and Paper Research, http://dx.doi.org/10.15376/frc.2022.1.291
    Conference Papers | 2021
    Alves D; Curvello R; Sparrow R; Garnier G, 2021, 'FREEZE-DRYING OXIDISED HUMAN RED BLOOD CELLS FOR BLOOD GROUP SEROLOGY DIAGNOSTICS', in INTERNAL MEDICINE JOURNAL, WILEY
    Conference Papers | 2021
    Curvello R; Kast V; Loessner D, 2021, 'Modeling the tumor microenvironment using tissue engineering technologies.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, pp. 49 - 49, presented at Conference of American Association for Cancer Research (AACR) - Pancreatic Cancer, ELECTR NETWORK, 29 September 2021 - 30 September 2021
    Conference Papers | 2019
    Curvello R; Dannappel M; Firestein R; Rosenbluh J; Tabor R; Garnier G, 2019, 'Nanocellulose hydrogel for organoids culture', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, FL, Orlando, presented at National Meeting of the American-Chemical-Society (ACS), FL, Orlando, 31 March 2019 - 04 April 2019
    Conference Papers | 2019
    Curvello R; Mendoza L; McLiesh H; Tabor R; Garnier G, 2019, 'Nanocellulose hydrogels for blood typing diagnostics', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, FL, Orlando, presented at National Meeting of the American-Chemical-Society (ACS), FL, Orlando, 31 March 2019 - 04 April 2019
    Conference Papers | 2019
    Manderson CA; McLiesh H; Curvello R; Tabor RF; Manolios J; Garnier G, 2019, 'PRETRANSFUSION TESTING USING LASER INCUBATION', in INTERNAL MEDICINE JOURNAL, WILEY, pp. 9 - 10
    Conference Papers | 2017
    Oliveira LP; Reno DL; Curvello RS; Lima LP; Galvao ACS, 2017, 'Evaluation of antitumor properties of metformin over human multidrug-resistant chronic myeloid leukemia cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-2105

Mollie Holman Award for the best PhD thesis, Faculty of Engineering, Monash University, Australia (2020)

Faculty of Engineering International Postgraduate Research Scholarship, Monash University, Australia (2017)

Best Biomedical Engineering Graduate, Regional Council of Engineering and Agronomy, Brazil (2016)