Miss Si Liu

Miss Si Liu

Research Associate
Engineering
School of Chemical Engineering

Dr Liu is currently a Postdoctoral Research Fellow in the School of Chemical Engineering at UNSW, as a member of Prof. Kang Liang’s research group. She received both her PhD (2024) and Master’s degree (2020) in Chemical Engineering from Tianjin University, China. Her research focuses on the design and fabrication of multifunctional nanomaterials, particularly reticular frameworks such as hydrogen-bonded organic frameworks (HOFs) and metal–organic frameworks (MOFs), for biomedical applications. These include targeted therapy, drug delivery, enzyme catalysis, imaging-guided treatment, and the development of MOF-based nanomotors for enhanced tumour penetration.

Dr Liu has published eight journal articles, including Angew. Chem. Int. Ed., Adv. Mater., and ACS Sustain. Chem. Eng. In addition, she has co-invented two patents and contributed to four book chapters in a nationally endorsed postgraduate textbook “Enzyme Engineering: Principle and Application”. She has supervised more than 10 Master’s and PhD students. She was awarded the UNSW Global Research and Impact Program (GRIP) Fellowship, enabling collaborative research with the University of California, San Diego (UCSD).

Phone
+61466219486
Location
High Street, Kennington New South Wales 2052
  • Journal articles | 2026
    Liu S; Deng P; Chen Q; Sun Q; Wang Y; Shi H; Liang K, 2026, 'Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts', Advanced Science, 13, http://dx.doi.org/10.1002/advs.202519207
    Journal articles | 2025
    Chen Q; Liu S; Qin P; Xue J; Deng P; Li Z; Whitelock J; Guo T; Liang K, 2025, 'Improving extracellular matrix penetration with biocatalytic metal-organic framework nanoswimmers', Journal of Materials Chemistry B, 13, pp. 8897 - 8907, http://dx.doi.org/10.1039/d5tb00509d
    Journal articles | 2025
    Deng P; Wang Y; Shi H; Chen Q; Xue J; Liu S; Sun Q; Lan D; Liu Y; Li H; Jiao W; Ge J; Liang K, 2025, 'Rapid and Selective Fluorescent Sensing of Nerve Agent Simulants Using Copper-Doped Lanthanide Metal-Organic Frameworks', Chemistry A European Journal, 31, http://dx.doi.org/10.1002/chem.202502728
    Journal articles | 2025
    Li H; Liu S; Guo Z; Sun Y, 2025, 'Polyelectrolyte-Assisted Nanotrap Engineering for In Situ Confining Cofactor-Dependent Multienzyme Cascade Systems in Covalent Organic Frameworks', ACS Applied Polymer Materials, 7, pp. 7233 - 7242, http://dx.doi.org/10.1021/acsapm.5c00838
    Journal articles | 2025
    Liu S; Wang Z; Wang L; Zhang S; Sun Y, 2025, 'Self-sufficient heterogeneous biocatalysis systems based on NAD(P) recycling: new perspectives on construction', Catalysis Reviews Science and Engineering, 67, pp. 130 - 172, http://dx.doi.org/10.1080/01614940.2023.2294215
    Journal articles | 2025
    Liu X; Liu S; Guo Z; Dong X; Sun Y, 2025, 'Behavior of the Bionanoreactor with Coencapsulated Cofactors and Enzymes in HOF-101 for Cascade Chiral Amine Synthesis', ACS Applied Nano Materials, 8, pp. 12037 - 12046, http://dx.doi.org/10.1021/acsanm.5c01612
    Journal articles | 2025
    Sun Q; Liu S; Li Z; Deng P; Niu N; Chen L; Liang K, 2025, 'Spatial Coordination Structure-Driven Enzyme-Like Selectivity in Single-Atom Nanozymes', Advanced Materials, 37, http://dx.doi.org/10.1002/adma.202508125
    Journal articles | 2024
    Liu S; Wu X; Dong X; Shi Q; Sun Y, 2024, 'Coencapsulating Anionic Cofactor and Silica Nanoparticle-Bound Enzymes in Cationic Microgel for Multienzyme Cascade Reaction with Cofactor Recycling', ACS Sustainable Chemistry and Engineering, 12, pp. 6366 - 6375, http://dx.doi.org/10.1021/acssuschemeng.4c00450
    Journal articles | 2023
    Liu S; Sun Y, 2023, 'Co-encapsulating Cofactor and Enzymes in Hydrogen-Bonded Organic Frameworks for Multienzyme Cascade Reactions with Cofactor Recycling', Angewandte Chemie International Edition, 62, http://dx.doi.org/10.1002/anie.202308562
    Journal articles | 2022
    Liu S; Wang Z; Chen K; Yu L; Shi Q; Dong X; Sun Y, 2022, 'Cascade chiral amine synthesis catalyzed by site-specifically co-immobilized alcohol and amine dehydrogenases', Catalysis Science and Technology, 12, pp. 4486 - 4497, http://dx.doi.org/10.1039/d2cy00514j

[1] UNSW university office global affairs & division of research global research and impact program
(GRIP): Developing solar-sensitive smart nanobioreactors for self-propelled, efficient
biodegradation of microplastics (grant no. PS74076).

1. Tianjin University Outstanding doctoral dissertation (2024)
2. Outstanding graduate of Tianjin University (2024)
3. Tianjin University Doctoral Forum 2022 | Outstanding Report Award
4. The 2nd International Conference on Advanced Biomanufacturing | Excellent Poster Award
5. Tianjin University Scholarship (2018-present)
6. Excellent Student of Tianjin University (2020-2021)
7. Excellent Student Cadre of Tianjin University (2021-2022)
8. Outstanding Communist Youth League Member of Tianjin University (2021-2022)

PATENTS
[1] Sun, Y., Liu, S., Dong, X. Y., and Shi, Q. H. Method of silica binding peptide mediating the coimmobilization
of alcohol and amine dehydrogenases for cascade synthesizing chiral amine.
CN114369593B, 2024-04-30.
[2] Sun, Y., Liu, S., Dong, X. Y., and Shi, Q. H. Method of polyelectrolyte assisting the construction
of immobilized catalytic systems based on hydrogen-bonded organic frameworks.
CN2023110434383a, filed August 2023. Patent Pending.