Associate Professor Stuart Turville
Senior Research Fellow

Associate Professor Stuart Turville

BSc (Hons I), PhD

Medicine & Health
The Kirby Institute

The overall goal of my present research work at the Kirby Institute is two-fold. Firstly to define the basic mechanisms of HIV spread, from tracking entry and fusion of single HIV virions through to the more logistically challenging task of tracking viral spread through cell-cell contact.  To date our laboratory is one of only a few laboratories worldwide that can image HIV spread in live HIV infected primary cell types (see image below to observe HIV (white) being lauched by cellular filopodia (red)).

The second component of my laboratory is currently involved and actively collaborating with research groups involved in using gene therapy for a treatment of a range of chronic diseases including HIV. Indeed a functional cure for HIV may lie in gene therapy. For instance, functional removal of human genes that HIV needs or attacking the viral genes directly, all represent ways to silence the viral reservoir in the long term. Whilst there are many approaches that work in cell line models, the present limitation to this approach is gene delivery. For instance the cells of the immune system that HIV attacks are unfortunately very difficult to deliver genes to. The broad aim of this project is to systematically determine the best protocol for gene delivery by using different combinations of viral proteins.

We are actively looking for capable honours, masters and PhD students who have a strong interest in the intersection of virology and cellular biology to undertake NHMRC funded projects.

 

 

Mobile
043 220 8645
Phone
+61 (02) 9385 0462
Location
Presently Located The Kirby Institute, UNSW Australia Office 529 Level 5 Wallace Wurth Building, UNSW, Sydney NSW 2052
  • Book Chapters | 2019
    Ognenovska K; Klemm V; Ledger S; Turville S; Symonds G; D. Kelleher A; L. Ahlenstiel C, 2019, 'Mechanisms for Controlling HIV-1 Infection: A Gene Therapy Approach', in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders, IntechOpen, http://dx.doi.org/10.5772/intechopen.79669
    Book Chapters | 2018
    Ognenovska K; Klemm V; Ledger S; Turville S; Symonds G; Kelleher A; Ahlenstiel CL, 2018, 'Mechanisms for Controlling HIV-1 infection: a Gene Therapy Approach', in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders, http://dx.doi.org/10.5772/intechopen.72962
    Book Chapters | 2008
    Vachot L; Turville SG; Trapp S; Peretti S; Morrow G; Frank I; Pope M, 2008, 'Sleeping with the Enemy: The Insidious Relationship between Dendritic Cells and Immunodeficiency Viruses', in Handbook of Dendritic Cells, pp. 773 - 811, http://dx.doi.org/10.1002/9783527619696.ch38
    Book Chapters | 2007
    Cunningham AL; Wilkinson J; Turville S; Pope M, 2007, 'Binding and uptake of HIV by dendritic cellsand transfer to T lymphocytes: Implicationsfor pathogenesis', in The Biology of Dendritic Cells and HIV Infection, pp. 381 - 404, http://dx.doi.org/10.1007/978-0-387-33785-2_10
  • Journal articles | 2022
    Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Stella AO; Kindinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Jean T; Foster CSP; Christ D; Hoppe AC; Munier ML; Darley D; Churchill M; Stark DJ; Matthews G; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern', eBioMedicine, vol. 84, pp. 104270, http://dx.doi.org/10.1016/j.ebiom.2022.104270
    Journal articles | 2022
    Aggarwal A; Stella A; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Lenthall H; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fitcher C; Hoppe AC; Munier CML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2022, 'SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern', , http://dx.doi.org/10.21203/rs.3.rs-1207364/v1
    Journal articles | 2022
    Aggarwal A; Stella AO; Henry CC; Narayan K; Turville SG, 2022, 'Embedding of HIV Egress within Cortical F-Actin', Pathogens, vol. 11, http://dx.doi.org/10.3390/pathogens11010056
    Journal articles | 2022
    Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, vol. 7, pp. 896 - 908, http://dx.doi.org/10.1038/s41564-022-01135-7
    Journal articles | 2022
    Ashhurst AS; Tang AH; Fajtová P; Yoon MC; Aggarwal A; Bedding MJ; Stoye A; Beretta L; Pwee D; Drelich A; Skinner D; Li L; Meek TD; McKerrow JH; Hook V; Tseng CT; Larance M; Turville S; Gerwick WH; O'Donoghue AJ; Payne RJ, 2022, 'Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L', Journal of Medicinal Chemistry, vol. 65, pp. 2956 - 2970, http://dx.doi.org/10.1021/acs.jmedchem.1c01494
    Journal articles | 2022
    Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson SC; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer DE; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2022, 'Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses', Cell Reports, vol. 38, pp. 110345, http://dx.doi.org/10.1016/j.celrep.2022.110345
    Journal articles | 2022
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Klemm V; Munier CML; Hoppe AC; Tea F; Pillay A; Stella AO; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses', American Journal of Hematology, http://dx.doi.org/10.1002/ajh.26619
    Journal articles | 2022
    Body A; Ahern E; Lal L; Gillett K; Abdulla H; Opat S; O’Brien T; Downie P; Turville S; Munier CML; Smith C; MacIntyre CR; Segelov E, 2022, 'Protocol for SARS-CoV-2 post-vaccine surveillance study in Australian adults and children with cancer: an observational study of safety and serological and immunological response to SARS-CoV-2 vaccination (SerOzNET)', BMC Infectious Diseases, vol. 22, pp. 70, http://dx.doi.org/10.1186/s12879-021-07019-1
    Journal articles | 2022
    Counoupas C; Pino P; Stella AO; Ashley C; Lukeman H; Bhattacharyya ND; Tada T; Anchisi S; Metayer C; Martinis J; Aggarwal A; Dcosta BM; Britton WJ; Kint J; Wurm MJ; Landau NR; Steain M; Turville SG; Wurm FM; David SA; Triccas JA, 2022, 'High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens', Microbiology Spectrum, vol. 10, http://dx.doi.org/10.1128/spectrum.01695-21
    Journal articles | 2022
    Duette G; Hiener B; Morgan H; Mazur FG; Mathivanan V; Horsburgh BA; Fisher K; Tong O; Lee E; Ahn H; Shaik A; Fromentin R; Hoh R; Bacchus-Souffan C; Nasr N; Cunningham AL; Hunt PW; Chomont N; Turville SG; Deeks SG; Kelleher AD; Schlub TE; Palmer S, 2022, 'The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells', Journal of Clinical Investigation, vol. 132, http://dx.doi.org/10.1172/JCI154422
    Journal articles | 2022
    Garcia-Valtanen P; Hope CM; Masavuli MG; Yeow AEL; Balachandran H; Mekonnen ZA; Al-Delfi Z; Abayasingam A; Agapiou D; Stella AO; Aggarwal A; Bouras G; Gummow J; Ferguson C; O'Connor S; McCartney EM; Lynn DJ; Maddern G; Gowans EJ; Reddi BAJ; Shaw D; Kok-Lim C; Beard MR; Weiskopf D; Sette A; Turville SG; Bull RA; Barry SC; Grubor-Bauk B, 2022, 'SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents', Cell Reports Medicine, vol. 3, pp. 100651, http://dx.doi.org/10.1016/j.xcrm.2022.100651
    Journal articles | 2022
    Johansen-Leete J; Ullrich S; Fry SE; Frkic R; Bedding MJ; Aggarwal A; Ashhurst AS; Ekanayake KB; Mahawaththa MC; Sasi VM; Luedtke S; Ford DJ; O'Donoghue AJ; Passioura T; Larance M; Otting G; Turville S; Jackson CJ; Nitsche C; Payne RJ, 2022, 'Antiviral cyclic peptides targeting the main protease of SARS-CoV-2', Chemical Science, vol. 13, pp. 3826 - 3836, http://dx.doi.org/10.1039/d1sc06750h
    Journal articles | 2022
    Kim KW; Wang X; Adhikari A; Yeang M; Jenkins F; Naing Z; Walker GJ; Foster CSP; Stelzer-Braid S; Deveson I; Craig ME; Tedla N; Bull RA; Martinello M; Pinto AN; Chan R; Turville S; Rawlinson WD; van Hal S, 2022, 'Persistent high-level shedding of cultivable SARS-CoV-2 Delta virus 33 days after onset of COVID-19 in a hospitalized patient with pneumonia', Journal of Medical Virology, vol. 94, pp. 4043 - 4046, http://dx.doi.org/10.1002/jmv.27832
    Journal articles | 2022
    Perkins G; Tunbridge M; Salehi T; Sheng Chai C; Hope CM; Garcia-Valtanen P; Singer JJ; Hurtado PR; Turville S; Hissaria P; Grubor-Bauk B; Barry SC; Chadban SJ; Coates AO T, 2022, '314.2: MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19', Transplantation, vol. 106, pp. S223 - S223, http://dx.doi.org/10.1097/01.tp.0000886512.07666.7d
    Journal articles | 2022
    Perkins GB; Tunbridge M; Salehi T; Chai CS; Kireta S; Johnston J; Penko D; Nitschke J; Yeow AEL; Al-Delfi Z; Drogemuller CJ; Garcia-Valtanen P; Masavuli MG; Hope CM; Singer J; Aggarwal A; Ospina Stella A; Turville SG; Hurtado PR; Barry SC; Hissaria P; Grubor-Bauk B; Chadban SJ; Coates PT, 2022, 'Concurrent vaccination of kidney transplant recipients and close household cohabitants against COVID-19', Kidney International, vol. 101, pp. 1077 - 1080, http://dx.doi.org/10.1016/j.kint.2022.02.015
    Journal articles | 2022
    Power H; Wu J; Turville S; Aggarwal A; Valtchev P; Schindeler A; Dehghani F, 2022, 'Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein', Bioorganic Chemistry, vol. 119, pp. 105574, http://dx.doi.org/10.1016/j.bioorg.2021.105574
    Journal articles | 2022
    Rankin K; Beaton B; Sasson S; Raedemaecker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Patel M; Klemm V; Munier CML; Carey Hoppe A; Tea F; Pillay A; Ospina A; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA', HemaSphere, vol. 6, pp. 1958 - 1959, http://dx.doi.org/10.1097/01.hs9.0000851180.32970.18
    Journal articles | 2022
    Segelov E; Body A; Lal L; Abdulla H; Turville S; Naing Z; Opat S; Leahy M; Balendra JR; Hamad N; Mccuaig R; Rao S; Lineburg K; Smith C; MacIntyre CR; Milch V; Busija L; Ahern ES, 2022, '1611P Clinical determinants of SARS-CoV-2 vaccine response in adults with cancer', Annals of Oncology, vol. 33, pp. S1279 - S1279, http://dx.doi.org/10.1016/j.annonc.2022.07.1704
    Journal articles | 2022
    Shen Y; Freeman JA; Holland J; Naidu K; Solterbeck A; Van Bilsen N; Downe P; Kerridge I; Wallman LL; Akerman A; Aggarwal A; Milogiannakis V; Martins Costa Gomes G; Doyle CM; Sandgren KJ; Turville S; Cunningham AL; Mulligan SP, 2022, 'Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion.', Blood, http://dx.doi.org/10.1182/blood.2022017814
    Journal articles | 2022
    Shen Y; Freeman JA; Holland J; Solterbeck A; Naidu K; Soosapilla A; Downe P; Tang C; Kerridge I; Wallman L; Van Bilsen N; Milogiannakis V; Akerman A; Martins Costa Gomes G; Sandgren K; Cunningham A; Turville S; Mulligan SP, 2022, 'COVID-19 vaccine failure in chronic lymphocytic leukaemia and monoclonal B-lymphocytosis; humoural and cellular immunity', British Journal of Haematology, vol. 197, pp. 41 - 51, http://dx.doi.org/10.1111/bjh.18014
    Journal articles | 2022
    Spillings BL; Day CJ; Garcia-Minambres A; Aggarwal A; Condon ND; Haselhorst T; Purcell DFJ; Turville SG; Stow JL; Jennings MP; Mak J, 2022, 'Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry', Cell Reports, vol. 38, http://dx.doi.org/10.1016/j.celrep.2022.110296
    Journal articles | 2021
    Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, vol. 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228
    Journal articles | 2021
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Warden A; Stella AO; Aggarwal A; Caterson ID; Phetsouphanh C; Turville S; Kelleher AD; Brilot F; Trotman J, 2021, 'Efficacy of Vaccine BNT162b2 (Pfizer-BioNTech) in Individuals with Waldenstrom's Macroglobulinemia and Follicular Lymphoma in Australia', BLOOD, vol. 138, http://dx.doi.org/10.1182/blood-2021-149348
    Journal articles | 2021
    Burnett DL; Jackson KJL; Langley DB; Aggrawal A; Stella AO; Johansen MD; Balachandran H; Lenthall H; Rouet R; Walker G; Saunders BM; Singh M; Li H; Henry JY; Jackson J; Stewart AG; Witthauer F; Spence MA; Hansbro NG; Jackson C; Schofield P; Milthorpe C; Martinello M; Schulz SR; Roth E; Kelleher A; Emery S; Britton WJ; Rawlinson WD; Karl R; Schäfer S; Winkler TH; Brink R; Bull RA; Hansbro PM; Jäck HM; Turville S; Christ D; Goodnow CC, 2021, 'Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability', Immunity, vol. 54, pp. 2908 - 2921.e6, http://dx.doi.org/10.1016/j.immuni.2021.10.019
    Journal articles | 2021
    Böcking T; Jacques DA; Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y, 2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, vol. 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250
    Journal articles | 2021
    Capraro A; Wong S; Adhikari A; Allan K; Patel H; Zhong L; Raftery M; Jaffe A; Yeang M; Aggarwal A; Wu L; Pandzic E; Whan R; Turville S; Vittorio O; Bull R; Kaakoush N; Rawlinson W; Tedla N; Vafaee F; Waters S, 2021, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453
    Journal articles | 2021
    Counoupas C; Johansen MD; Stella AO; Nguyen DH; Ferguson AL; Aggarwal A; Bhattacharyya ND; Grey A; Hutchings O; Patel K; Siddiquee R; Stewart EL; Feng CG; Hansbro NG; Palendira U; Steain MC; Saunders BM; Low JKK; Mackay JP; Kelleher AD; Britton WJ; Turville SG; Hansbro PM; Triccas JA, 2021, 'A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection', npj Vaccines, vol. 6, http://dx.doi.org/10.1038/s41541-021-00406-4
    Journal articles | 2021
    Estcourt LJ; Turgeon AF; McQuilten ZK; McVerry BJ; Al-Beidh F; Annane D; Arabi YM; Arnold DM; Beane A; Bégin P; Van Bentum-Puijk W; Berry LR; Bhimani Z; Birchall JE; Bonten MJM; Bradbury CA; Brunkhorst FM; Buxton M; Callum JL; Chassé M; Cheng AC; Cove ME; Daly J; Derde L; Detry MA; De Jong M; Evans A; Fergusson DA; Fish M; Fitzgerald M; Foley C; Goossens H; Gordon AC; Gosbell IB; Green C; Haniffa R; Harvala H; Higgins AM; Hills TE; Hoad VC; Horvat C; Huang DT; Hudson CL; Ichihara N; Laing E; Lamikanra AA; Lamontagne F; Lawler PR; Linstrum K; Litton E; Lorenzi E; Maclennan S; Marshall J; McAuley DF; McDyer JF; McGlothlin A; McGuinness S; Miflin G; Montgomery S; Mouncey PR; Murthy S; Nichol A; Parke R; Parker JC; Priddee N; Purcell DFJ; Reyes LF; Richardson P; Robitaille N; Rowan KM; Rynne J; Saito H; Santos M; Saunders CT; Serpa Neto A; Seymour CW; Silversides JA; Tinmouth AA; Triulzi DJ; Turner AM; Van De Veerdonk F; Walsh TS; Wood EM; Berry S; Lewis RJ; Menon DK; McArthur C; Zarychanski R; Angus DC; Webb SA; Roberts DJ; Shankar-Hari M, 2021, 'Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients with COVID-19: A Randomized Clinical Trial', JAMA - Journal of the American Medical Association, vol. 326, pp. 1690 - 1702, http://dx.doi.org/10.1001/jama.2021.18178
    Journal articles | 2021
    Fichter C; Aggarwal A; Wong AKH; McAllery S; Mathivanan V; Hao B; Macrae H; Churchill MJ; Gorry PR; Roche M; Gray LR; Turville S, 2021, 'Modular lentiviral vectors for highly efficient transgene expression in resting immune cells', Viruses, vol. 13, pp. 1170 - 1170, http://dx.doi.org/10.3390/v13061170
    Journal articles | 2021
    Li L; Honda-Okubo Y; Huang Y; Jang H; Carlock MA; Baldwin J; Piplani S; Bebin-Blackwell AG; Forgacs D; Sakamoto K; Stella A; Turville S; Chataway T; Colella A; Triccas J; Ross TM; Petrovsky N, 2021, 'Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection', Vaccine, vol. 39, pp. 5940 - 5953, http://dx.doi.org/10.1016/j.vaccine.2021.07.087
    Journal articles | 2021
    Norman A; Franck C; Christie M; Hawkins PME; Patel K; Ashhurst AS; Aggarwal A; Low JKK; Siddiquee R; Ashley CL; Steain M; Triccas JA; Turville S; MacKay JP; Passioura T; Payne RJ, 2021, 'Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display', ACS Central Science, vol. 7, pp. 1001 - 1008, http://dx.doi.org/10.1021/acscentsci.0c01708
    Journal articles | 2021
    Rouet R; Mazigi O; Walker GJ; Langley DB; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry JY; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull RA; Turville S; Stewart AG; Goodnow CC; Rawlinson WD; Christ D, 2021, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', mAbs, vol. 13, pp. 1922134, http://dx.doi.org/10.1080/19420862.2021.1922134
    Journal articles | 2021
    Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Fichter C; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffmann M; Pöhlman S; Mazigi O; Christ D; Rockett RJ; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2021, 'SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants', PLoS Medicine, vol. 18, http://dx.doi.org/10.1371/journal.pmed.1003656
    Journal articles | 2021
    Walker GJ; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs SR; Agapiou D; Bull RA; Stelzer-Braid S; Daly J; Gosbell IB; Hoad VC; Irving DO; Pink JM; Turville S; Kelleher AD; Rawlinson WD, 2021, 'Sars coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays', Viruses, vol. 13, pp. 247 - 247, http://dx.doi.org/10.3390/v13020247
    Journal articles | 2020
    Lau D; Walsh JC; Mousapasandi A; Ariotti N; Shah VB; Turville S; Jacques DA; Böcking T, 2020, 'Self-Assembly of Fluorescent HIV Capsid Spheres for Detection of Capsid Binders', Langmuir, vol. 36, pp. 3624 - 3632, http://dx.doi.org/10.1021/acs.langmuir.0c00103
    Journal articles | 2020
    Rouet R; Mazigi O; Walker G; Langley D; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry J; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull R; Turville S; Stewart A; Goodnow C; Rawlinson W; Christ D, 2020, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', , http://dx.doi.org/10.1101/2020.12.14.422791
    Journal articles | 2020
    Stelzer-Braid S; Walker GJ; Aggarwal A; Isaacs SR; Yeang M; Naing Z; Ospina Stella A; Turville SG; Rawlinson WD, 2020, 'Virus isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for diagnostic and research purposes', Pathology, vol. 52, pp. 760 - 763, http://dx.doi.org/10.1016/j.pathol.2020.09.012
    Journal articles | 2020
    Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffman M; Pöhlmann S; Dwyer DE; Rockett R; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2020, 'SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants', , http://dx.doi.org/10.1101/2020.12.19.20248567
    Journal articles | 2020
    Van Bockel D; Munier CML; Turville S; Badman SG; Walker G; Stella AO; Aggarwal A; Yeang M; Condylios A; Kelleher AD; Applegate TL; Vallely A; Whiley D; Rawlinson W; Cunningham P; Kaldor J; Guy R, 2020, 'Evaluation of commercially available viral transport medium (VTM) for SARS-CoV-2 inactivation and use in point-of-care (POC) testing', Viruses, vol. 12, pp. 1208 - 1208, http://dx.doi.org/10.3390/v12111208
    Journal articles | 2020
    Walker G; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein L; Rawlinson W, 2020, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage', , http://dx.doi.org/10.1101/2020.06.18.20134395
    Journal articles | 2020
    Walker G; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs S; Agapiou D; Bull R; Stelzer-Braid S; Daly J; Gosbell I; Hoad V; Irving D; Pink J; Turville S; Kelleher A; Rawlinson W, 2020, 'SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays', , http://dx.doi.org/10.1101/2020.12.07.20245696
    Journal articles | 2020
    Walker GJ; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein LD; Rawlinson W, 2020, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurisation but not cold storage', Journal of Paediatrics and Child Health, vol. 56, pp. 1872 - 1874, http://dx.doi.org/10.1111/jpc.15065
    Journal articles | 2019
    Aggarwal A; Ospina Stella A; Henry C; Narayan K; Turville S, 2019, 'HIV corruption of the Arp2/3-Cdc42-IQGAP1 axis to hijack cortical F-Actin to promote cell-cell viral spread', , http://dx.doi.org/10.1101/2019.12.13.873612
    Journal articles | 2019
    Ahlenstiel CL; Turville SG, 2019, 'Delivery of gene therapy to resting immune cells for an HIV cure', Current Opinion in HIV and AIDS, vol. 14, pp. 129 - 136, http://dx.doi.org/10.1097/COH.0000000000000531
    Journal articles | 2019
    Bertram KM; Tong O; Royle C; Turville SG; Nasr N; Cunningham AL; Harman AN, 2019, 'Manipulation of mononuclear phagocytes by HIV: Implications for early transmission events', Frontiers in Immunology, vol. 10, http://dx.doi.org/10.3389/fimmu.2019.02263
    Journal articles | 2019
    Hu W; Cai Y; Zhu Y; Li F; Stella AO; Tebas P; Mounzer K; Kostman J; Turville S; Montaner L, 2019, 'Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle', Journal of Virus Eradication, vol. 5, pp. 55 - 56, http://dx.doi.org/10.1016/s2055-6640(20)30221-1
    Journal articles | 2019
    Lau D; Walsh J; Peng W; Shah V; Turville S; Jacques D; Böcking T, 2019, 'Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes', , http://dx.doi.org/10.1101/619841
    Journal articles | 2019
    Lau D; Walsh JC; Peng W; Shah VB; Turville S; Jacques DA; Böcking T, 2019, 'Fluorescence Biosensor for Real-Time Interaction Dynamics of Host Proteins with HIV-1 Capsid Tubes', ACS Applied Materials and Interfaces, vol. 11, pp. 34586 - 34594, http://dx.doi.org/10.1021/acsami.9b08521
    Journal articles | 2019
    Marquez CL; Lau D; Walsh J; Faysal KMR; Parker MW; Turville SG; Bocking T, 2019, 'Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro', BIO-PROTOCOL, vol. 9, http://dx.doi.org/10.21769/BioProtoc.3297
    Journal articles | 2019
    Rhodes JW; Tong O; Harman AN; Turville SG, 2019, 'Human dendritic cell subsets, ontogeny, and impact on HIV infection', Frontiers in Immunology, vol. 10, pp. 1088, http://dx.doi.org/10.3389/fimmu.2019.01088
    Journal articles | 2018
    Ledger S; Howe A; Turville S; Aggarwal A; Savkovic B; Ong A; Wolstein O; Boyd M; Millington M; Gorry PR; Murray JM; Symonds G, 2018, 'Analysis and dissociation of anti-HIV effects of shRNA to CCR5 and the fusion inhibitor C46', Journal of Gene Medicine, vol. 20, http://dx.doi.org/10.1002/jgm.3006
    Journal articles | 2018
    Márquez CL; Lau D; Walsh J; Shah V; McGuinness C; Wong A; Aggarwal A; Parker MW; Jacques DA; Turville S; Böcking T, 2018, 'Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.34772
    Journal articles | 2018
    Stella AO; Turville S, 2018, 'All-round manipulation of the actin cytoskeleton by HIV', Viruses, vol. 10, http://dx.doi.org/10.3390/v10020063
    Journal articles | 2018
    Turville S; Kelleher A, 2018, 'Obituary: Remembering Professor David Cooper', Retrovirology, vol. 15, pp. 40, http://dx.doi.org/10.1186/s12977-018-0418-1
    Journal articles | 2017
    Aggarwal A; Hitchen TL; Ootes L; McAllery S; Wong A; Nguyen K; McCluskey A; Robinson PJ; Turville SG, 2017, 'HIV infection is influenced by dynamin at 3 independent points in the viral life cycle', Traffic, vol. 18, pp. 392 - 410, http://dx.doi.org/10.1111/tra.12481
    Journal articles | 2017
    Aggarwal A; Turville SG, 2017, 'Resolving the Sites of HIV Entry: Dynamin Networks Hold the Key', Journal of Cell Signaling, vol. 02, http://dx.doi.org/10.4172/2576-1471.1000173
    Journal articles | 2017
    Xu Y; Phetsouphanh C; Suzuki K; Aggrawal A; Graff-Dubois S; Roche M; Bailey M; Alcantara S; Cashin K; Sivasubramaniam R; Koelsch KK; Autran B; Harvey R; Gorry PR; Moris A; Cooper DA; Turville S; Kent SJ; Kelleher AD; Zaunders J, 2017, 'HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells', Frontiers in Immunology, vol. 8, http://dx.doi.org/10.3389/fimmu.2017.00376
    Journal articles | 2016
    McAllery SA; Ahlenstiel CL; Suzuki K; Symonds GP; Kelleher AD; Turville SG, 2016, 'The feasibility of incorporating Vpx into lentiviral gene therapy vectors', Molecular Therapy - Methods and Clinical Development, vol. 3, pp. 16066, http://dx.doi.org/10.1038/mtm.2016.66
    Journal articles | 2016
    Ng WC; Londrigan SL; Nasr N; Cunningham AL; Turville S; Brooks AG; Reading PC, 2016, 'The C-type lectin langerin functions as a receptor for attachment and infectious entry of influenza A virus', Journal of Virology, vol. 90, pp. 206 - 221, http://dx.doi.org/10.1128/JVI.01447-15
    Journal articles | 2015
    Ahlenstiel C; Mendez C; Lim STH; Marks K; Turville S; Cooper DA; Kelleher AD; Suzuki K, 2015, 'Novel RNA duplex locks HIV-1 in a latent state via chromatin-mediated transcriptional silencing', Molecular Therapy - Nucleic Acids, vol. 4, pp. e261, http://dx.doi.org/10.1038/mtna.2015.31
    Journal articles | 2015
    Jayathunge PHM; McBride WJH; Maclaren D; Kaldor J; Vallely A; Turville S, 2015, 'Male circumcision and HIV transmission; What do we know?', Open AIDS Journal, vol. 8, pp. 31 - 44, http://dx.doi.org/10.2174/1874613601408010031
    Journal articles | 2015
    Tong WWY; Turville S; Roberts J; Zaunders J; Jin F; Poynten IM; Hillman RJ; Grulich AE; Kelleher AD; Carr A, 2015, 'P10.10 T-cells in the anal mucosa of men with high-grade squamous intraepithelial lesions', Sexually Transmitted Infections, vol. 91, pp. A168.2 - A168, http://dx.doi.org/10.1136/sextrans-2015-052270.438
    Journal articles | 2014
    Aggarwal A; Turville SG, 2014, 'Imaging HIV entry and egress', Microbiology Australia
    Journal articles | 2014
    Eyre NS; Fiches GN; Aloia AL; Helbig KJ; McCartney EM; McErlean CSP; Li K; Aggarwal A; Turville SG; Beard MR, 2014, 'Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection', Journal of Virology, vol. 88, pp. 3636 - 3652, http://dx.doi.org/10.1128/JVI.02490-13
    Journal articles | 2014
    Gray LR; Turville SG; HItchen TL; Cheng WJ; Ellett AM; Salimi H; Roche MJ; Wesselingh SL; Gorry PR; Churchill MJ, 2014, 'HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0090620
    Journal articles | 2014
    Gray LR; Turville SG; Hitchen TL; Cheng WJ; Ellett AM, 2014, 'Correction: HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles (PLoS ONE (2014) 9, 2, (e90620) DOI:10.1371/journal.pone.0090620)', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0093417
    Journal articles | 2014
    Nasr N; Harman A; Turville S; Cunningham AL, 2014, 'HIV infection of dendritic cells', Methods in Molecular Biology, vol. 1087, pp. 221 - 232, http://dx.doi.org/10.1007/978-1-62703-670-2-18
    Journal articles | 2014
    Nasr N; Harman A; Turville S; Cunningham AL, 2014, 'HIV infection of dendritic cells', Methods in Molecular Biology, vol. 1087, pp. 221 - 232, http://dx.doi.org/10.1007/978-1-62703-670-2_18
    Journal articles | 2014
    Turville S, 2014, 'Blocking of HIV entry through CD44-hyaluronic acid interactions', Immunology and Cell Biology, vol. 92, pp. 735 - 736, http://dx.doi.org/10.1038/icb.2014.66
    Journal articles | 2014
    Turville SG; Nasr N; Lai J; Botting RA; Mercier SK; Harman AN; Kim M; Centre RJ; Domagala T; Gorry PR; Olbourne N; Cunningham AL, 2014, 'Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerin', J Immunol, vol. 193, pp. 2554 - 2564, http://dx.doi.org/10.4049/jimmunol.1400630
    Journal articles | 2013
    2013, 'The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0062196
    Journal articles | 2013
    Aggarwal A; Mcallery S; Turville S, 2013, 'Revising the role of myeloid cells in HIV pathogenesis', Current HIV/AIDS Reports, vol. 10, pp. 3 - 11, http://dx.doi.org/10.1007/s11904-012-0149-1
    Journal articles | 2013
    Mercier SK; Donaghy H; Botting RA; Turville SG; Harman AN; Nasr N; Ji H; Kusebauch U; Mendoza L; Shteynberg D; Sandgren K; Simpson RJ; Moritz RL; Cunningham AL, 2013, 'Correction: The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes', PLoS Pathogens, vol. 9, http://dx.doi.org/10.1371/annotation/059beb14-db84-4836-9fef-ec351946025a
    Journal articles | 2013
    Mercier SK; Donaghy H; Botting RA; Turville SG; Harman AN; Nasr N; Ji H; Kusebauch U; Mendoza L; Shteynberg D; Sandgren K; Simpson RJ; Moritz RL; Cunningham AL, 2013, 'The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes', PLoS Pathogens, vol. 9, http://dx.doi.org/10.1371/journal.ppat.1003700
    Journal articles | 2012
    Aggarwal A; Iemma T; Shih I; Newsome TP; Mcallery S; Cunningham A; Turville S, 2012, 'Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells', PLoS Pathogens, vol. 8, pp. e1002762, http://dx.doi.org/10.1371/journal.ppat.1002762
    Journal articles | 2012
    Gray L; Tachedjian G; Ellett A; Roche M; Brew B; Turville S; Wesselingh S; Gorry P; Churchill M, 2012, 'Reduced Effectiveness of the NRTIs d4T and AZT in Astrocytes: Implications for Neuro-cART', JOURNAL OF NEUROVIROLOGY, vol. 18, pp. 42 - 43, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800089&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Nasr N; Maddocks S; Turville S; Harman AN; Woolger N; Helbig KJ; Wilkinson J; Bye CR; Wright TK; Rambukwelle D; Donaghy H; Beard MR; Cunningham AL, 2012, 'HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.', Blood, vol. 120, pp. 778 - 788, http://dx.doi.org/10.1182/blood-2012-01-407395
    Journal articles | 2012
    Purcell DJ; Cunningham AL; Turville S; Tachedjian TG; Landay A, 2012, 'Biology of Mucosally Transmitted Sexual Infection-Translating the Basic Science into Novel HIV Intervention: A Workshop Summary', AIDS Research and Human Retroviruses, vol. 28, pp. 1389 - 1396, http://dx.doi.org/10.1089/aid.2012.0276
    Journal articles | 2011
    Harman AN; Lai J; Turville S, 2011, 'HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production (Blood (2011) 118, 2 (298-308))', Blood, vol. 118, pp. 6992, http://dx.doi.org/10.1182/blood-2011-10-384719
    Journal articles | 2011
    Harman AN; Lai J; Turville S; Samarajiwa S; Gray L; Marsden V; Mercier S; Jones K; Nasr N; Rustagi A; Cumming H; Donaghy H; Mak J; Gale M; Churchill M; Hertzog P; Cunningham AL, 2011, 'HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production', Blood, vol. 118, pp. 298 - 308, http://dx.doi.org/10.1182/blood-2010-07-297721
    Journal articles | 2011
    Keller CW; Fokken C; Turville SG; Lünemann A; Schmidt J; Münz C; Lünemann JD, 2011, 'TNF-α induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells', Journal of Biological Chemistry, vol. 286, pp. 3970 - 3980, http://dx.doi.org/10.1074/jbc.M110.159392
    Journal articles | 2011
    Londrigan SL; Turville SG; Tate MD; Deng YM; Brooks AG; Reading PC, 2011, 'N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN', Journal of Virology, vol. 85, pp. 2990 - 3000, http://dx.doi.org/10.1128/JVI.01705-10
    Journal articles | 2010
    Cunningham AL; Abendroth A; Jones C; Nasr N; Turville S, 2010, 'Viruses and Langerhans cells', Immunology and Cell Biology, vol. 88, pp. 416 - 423, http://dx.doi.org/10.1038/icb.2010.42
    Journal articles | 2010
    Cunningham AL; Donaghy H; Harman AN; Kim M; Turville SG, 2010, 'Manipulation of dendritic cell function by viruses', Current Opinion in Microbiology, vol. 13, pp. 524 - 529, http://dx.doi.org/10.1016/j.mib.2010.06.002
    Journal articles | 2009
    Harman AN; Kraus M; Bye CR; Byth K; Turville SG; Tang O; Mercier SK; Nasr N; Stern JL; Slobedman B; Driessen C; Cunningham AL, 2009, 'HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase', Blood, vol. 114, pp. 85 - 94, http://dx.doi.org/10.1182/blood-2008-12-194845
    Journal articles | 2009
    Lai J; Bernhard OK; Turville SG; Harman AN; Wilkinson J; Cunningham AL, 2009, 'Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1', Journal of Biological Chemistry, vol. 284, pp. 11027 - 11038, http://dx.doi.org/10.1074/jbc.M809698200
    Journal articles | 2009
    Trapp S; Derby NR; Singer R; Shaw A; Williams VG; Turville SG; Bess JW; Lifson JD; Robbiani M, 2009, 'Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G', Journal of Virology, vol. 83, pp. 884 - 895, http://dx.doi.org/10.1128/JVI.00023-08
    Journal articles | 2008
    Frank I; Stössel H; Gettie A; Turville SG; Bess JW; Lifson JD; Sivin I; Romani N; Robbiani M, 2008, 'A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells', Journal of Virology, vol. 82, pp. 5329 - 5339, http://dx.doi.org/10.1128/JVI.01987-07
    Journal articles | 2008
    Keller CW; Lee M; Turville SG; Bähr M; Münz C; Lünemann JD; Schmidt J, 2008, 'Akkumulation von beta-Amyloid im Skelettmuskel: Zytokin-induzierte Modulation von Makroautophagie', Aktuelle Neurologie, vol. 35, http://dx.doi.org/10.1055/s-0028-1086702
    Journal articles | 2008
    Schweizer A; Rusert P; Berlinger L; Ruprecht CR; Mann A; Corthésy S; Turville SG; Aravantinou M; Fischer M; Robbiani M; Amstutz P; Trkola A, 2008, 'CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics', PLoS Pathogens, vol. 4, http://dx.doi.org/10.1371/journal.ppat.1000109
    Journal articles | 2008
    Turville SG; Aravantinou M; Miller T; Kenney J; Teitelbaum A; Hu L; Chudolij A; Zydowsky TM; Piatak M; Bess JW; Lifson JD; Blanchard J; Gettie A; Robbiani M, 2008, 'Efficacy of carraguard®-based microbicides in vivo despite variable in vitro activity', PLoS ONE, vol. 3, http://dx.doi.org/10.1371/journal.pone.0003162
    Journal articles | 2008
    Turville SG; Aravantinou M; Stössel H; Romani N; Robbiani M, 2008, 'Resolution of de novo HIV production and trafficking in immature dendritic cells', Nature Methods, vol. 5, pp. 75 - 85, http://dx.doi.org/10.1038/nmeth1137
    Journal articles | 2007
    Fernández-Romero JA; Thorn M; Turville SG; Titchen K; Sudol K; Li J; Miller T; Robbiani M; Maguire RA; Buckheit RW; Hartman TL; Phillips DM, 2007, 'Carrageenan/MIV-150 (PC-815), a combination microbicide', Sexually Transmitted Diseases, vol. 34, pp. 9 - 14, http://dx.doi.org/10.1097/01.olq.0000223287.46097.4b
    Journal articles | 2006
    Lynch GW; Turville S; Carter B; Sloane AJ; Chan A; Muljadi N; Li S; Low L; Armati P; Raison R; Zoellner H; Williamson P; Cunningham A; Church WB, 2006, 'Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: Resolution of a novel CD4 isoform', Immunology and Cell Biology, vol. 84, pp. 154 - 165, http://dx.doi.org/10.1111/j.1440-1711.2005.01403.x
    Journal articles | 2006
    Trapp S; Turville SG; Robbiani M, 2006, 'Slamming the door on unwanted guests: Why preemptive strikes at the mucosa may be the best strategy against HIV', Journal of Leukocyte Biology, vol. 80, pp. 1076 - 1083, http://dx.doi.org/10.1189/jlb.0206121
    Journal articles | 2006
    Turville SG; Peretti S; Pope M, 2006, 'Lymphocyte-dendritic cell interactions and mucosal acquisition of SIV/HIV infection.', Curr Opin HIV AIDS, vol. 1, pp. 3 - 9, http://dx.doi.org/10.1097/01.COH.0000194109.14601.20
    Journal articles | 2005
    Sloane AJ; Raso V; Dimitrov DS; Xiao X; Deo S; Muljadi N; Restuccia D; Turville S; Kearney C; Broder CC; Zoellner H; Cunningham AL; Bendall L; Lynch GW, 2005, 'Marked structural and functional heterogeneity in CXCR4: Separation of HIV-1 and SDF-1α responses', Immunology and Cell Biology, vol. 83, pp. 129 - 143, http://dx.doi.org/10.1111/j.1440-1711.2004.01304.x
    Journal articles | 2005
    Turville SG; Vermeire K; Balzarini J; Schols D, 2005, 'Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer', Journal of Virology, vol. 79, pp. 13519 - 13527, http://dx.doi.org/10.1128/JVI.79.21.13519-13527.2005
    Journal articles | 2004
    Turville SG; Santos JJ; Frank I; Cameron PU; Wilkinson J; Miranda-Saksena M; Dable J; Stõssel H; Romani N; Piatak M; Lifson JD; Pope M; Cunningham AL, 2004, 'Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells', Blood, vol. 103, pp. 2170 - 2179, http://dx.doi.org/10.1182/blood-2003-09-3129
    Journal articles | 2003
    Kedzierska K; Crowe SM; Turville S; Cunningham AL, 2003, 'The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages', Reviews in Medical Virology, vol. 13, pp. 39 - 56, http://dx.doi.org/10.1002/rmv.369
    Journal articles | 2003
    Lynch GW; Slaytor EK; Elliott FD; Saurajen A; Turville SG; Sloane AJ; Cameron PU; Cunningham AL; Halliday GM, 2003, 'CD4 is expressed by epidermal Langerhans' cells predominantly as covalent dimers', Experimental Dermatology, vol. 12, pp. 700 - 711, http://dx.doi.org/10.1034/j.1600-0625.2003.00078.x
    Journal articles | 2003
    Turville S; Wilkinson J; Cameron P; Dable J; Cunningham AL, 2003, 'The role of dendritic cell C-type lectin receptors in HIV pathogenesis', Journal of Leukocyte Biology, vol. 74, pp. 710 - 718, http://dx.doi.org/10.1189/jlb.0503208
    Journal articles | 2002
    Turville SG; Cameron PU; Derek H; Cunningham AL, 2002, 'C-type lectin-HIV attachment on dendritic cells:Innate immune recognition and processing or mediators of HIV transmission?', Trends in Glycoscience and Glycotechnology, vol. 14, pp. 255 - 271, http://dx.doi.org/10.4052/tigg.14.255
    Journal articles | 2002
    Turville SG; Cameron PU; Handley A; Lin G; Pöhlmann S; Doms RW; Cunningham AL, 2002, 'Diversity of receptors binding HIV on dendritic cell subsets', Nature Immunology, vol. 3, pp. 975 - 983, http://dx.doi.org/10.1038/ni841
    Journal articles | 2001
    Turville SG; Arthos J; MacDonald K; Lynch G; Naif H; Clark G; Hart D; Cunningham AL, 2001, 'HIV gp120 receptors on human dendritic cells', Blood, vol. 98, pp. 2482 - 2488, http://dx.doi.org/10.1182/blood.V98.8.2482
    Journal articles | 2000
    Turville SG; Cameron PU; Arthos J; MacDonald K; Clark G; Hart D; Cunningham AL, 2000, 'Sweet symphony', New Scientist, vol. 166, pp. 11, http://dx.doi.org/10.1016/S1386-6532(01)00194-9
  • Preprints | 2022
    Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Coppola G; Yeang M; Jean T; Foster C; Hoppe AC; Ling Munier M; Darley D; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, 2022, SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, http://dx.doi.org/10.1101/2022.07.07.22277128
    Preprints | 2022
    Aggarwal A; Stella A; Akerman A; Walker G; Milogiannakis V; McAllery S; Esneau C; Silva MR; Lu Y; Forster C; Hal SV; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Darley D; Matthews G; Starck D; Robosa R; Bartlett N; Rawlinson W; Kelleher A; Turville S, 2022, Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants, http://dx.doi.org/10.21203/rs.3.rs-1210846/v1
    Preprints | 2022
    Ashhurst A; Johansen M; Maxwell J; Ashley C; Aggarwal A; Siddiquee R; Miemczyk S; Nguyen D; Mackay J; Counoupas C; Byrne S; Turville S; Steain M; Triccas J; Hansbro P; Payne R; Britton W, 2022, Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice, http://dx.doi.org/10.21203/rs.3.rs-1179181/v1
    Preprints | 2022
    Faysal KMR; Renner N; Marquez CL; Shah V; Tuckwell AJ; Christie MP; Parker MW; Turville SG; James L; Towers GJ; Jacques DA; Boecking T, 2022, Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure, http://dx.doi.org/10.1101/2022.09.21.508807
    Preprints | 2022
    Loo L; Waller M; Cole A; Stella A; Moreno C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddiquee R; Mackay J; Turville S; Hesselson D; Neely G, 2022, LRRC15 suppresses SARS-CoV-2 infection and controls collagen production, http://dx.doi.org/10.21203/rs.3.rs-1172665/v1
    Preprints | 2022
    Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks M; Law H; Danwilai T; Starr M; Munier ML; Christ D; Singh M; Croucher P; Brilot-Turville F; Turville S; Phan TG; Dore G; Darley D; Cunningham P; Matthews G; Kelleher A; Zaunders J, 2022, High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells, http://dx.doi.org/10.1101/2022.07.22.22277947
    Preprints | 2022
    Rouet R; Henry J; Johansen M; Sobti M; Balachandran H; Langley D; Walker G; Lenthall H; Jackson J; Ubiparipovic S; Mazigi O; Schofield P; Burnett D; Brown S; Martinello M; Hudson B; Gilroy N; Post J; Kelleher A; Jäck H-M; Goodnow C; Turville S; Rawlinson W; Bull R; Stewart A; Hansbro P; Christ D, 2022, Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients, http://dx.doi.org/10.1101/2022.10.19.512954
    Conference Abstracts | 2022
    Segelov E; Body A; Luong V; Lopez VA; Lal L; Abdulla H; Turville S; Niang Z; Opat S; McCuaig R; Lineburg K; Rao S; Smith C; MacIntyre R; Ahern E, 2022, 'Abstract CT259: Comprehensive humoral and cellular immune assessments to SARS-CoV-2 (wild type, delta and omicron) following two- and three-dose vaccination schedule in a large adult cancer population: SerOzNET study: placeholder abstract', in Cancer Research, American Association for Cancer Research (AACR), Vol. 82, pp. CT259 - CT259, http://dx.doi.org/10.1158/1538-7445.am2022-ct259
    Conference Abstracts | 2022
    Segelov E; Body A; Luong VTT; Aedo Lopez V; Lal L; Abdulla H; Turville S; Naing Z; Opat S; McCuaig R; Rao S; Lineburg K; Smith C; MacIntyre C; Ahern ES, 2022, 'Humoral and cellular immune response to Sars-CoV-2 wild-type and variants of concern following 3-dose vaccination in a large cohort of adults with cancer: The SerOzNET study.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. LBA12065 - LBA12065, http://dx.doi.org/10.1200/jco.2022.40.17_suppl.lba12065
    Conference Abstracts | 2022
    Segelov E; Body A; Turville S; Smith C; Lineburg K; Rao S; McCuaig R; Opat S; Niang Z; Lal L; Luong V; Abdulla H; Lopez VA; Padhye B; Bolanos NF; Anazodo A; MacIntyre R; Downie P; O'Brien T; Ahern E, 2022, 'Abstract CT567: Comprehensive measures of COVID-19 vaccine efficacy in adolescent cancer patients: Results from SerOzNET', in Cancer Research, American Association for Cancer Research (AACR), Vol. 82, pp. CT567 - CT567, http://dx.doi.org/10.1158/1538-7445.am2022-ct567
    Preprints | 2021
    Aggarwal A; Stella AO; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Henry J; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fichter C; Hoppe AC; Munier ML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2021, SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, http://dx.doi.org/10.1101/2021.12.14.21267772
    Preprints | 2021
    Counoupas C; Pino P; Stella A; Ashley C; Lukeman H; Bhattacharyya N; Tada T; Anchisi S; Metayer C; Martinis J; Aggarwal A; Dcosta B; Kint J; Wurm M; Landau N; Steain M; Turville S; Wurm F; David S; Triccas J, 2021, Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens, http://dx.doi.org/10.1101/2021.08.18.456891
    Preprints | 2021
    Garcia-Valtanen P; Hope C; Masavuli M; Lip Yeow AE; Balachandran H; Mekonnen Z; Al-Delfi Z; Abayasingam A; Agapiou D; Stella AO; Aggarwal A; Gummow J; Ferguson C; O’Connor S; McCartney E; Lynn D; Maddern G; Gowans E; Reddi BAJ; Shaw D; Kok-Lim C; Turville S; Beard M; Weiskopf D; Sette A; Bull R; Barry S; Grubor-Bauk B, 2021, COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection, http://dx.doi.org/10.1101/2021.11.08.21266035
    Preprints | 2021
    Johansen-Leete J; Ullrich S; Fry S; Frkic R; Bedding M; Aggarwal A; Ashhurst A; Ekanayake K; Mahawaththa M; Sasi V; Passioura T; Larance M; Otting G; Turville S; Jackson C; Nitsche C; Payne R, 2021, Discovery of Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 via mRNA Display, http://dx.doi.org/10.1101/2021.08.23.457419
    Conference Abstracts | 2021
    Klemm V; Czuba-Wojnilowicz E; Cortez-Jugo C; Turville SG; Agarwal A; Caruso F; Kelleher AD; Ahlenstiel CL, 2021, 'LAYER-BY-LAYER PARTICLES DELIVER EPIGENETIC SILENCING SIRNA TO HIV-1 LATENT RESERVOIR CELL TYPES', in SEXUAL HEALTH, CSIRO PUBLISHING, Vol. 18, pp. XII - XII, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000693686000022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2021
    Li L; Honda-Okubo Y; Huang Y; Jang H; Carlock MA; Baldwin J; Piplani S; Bebin-Blackwell AG; Forgacs D; Sakamoto K; Stella A; Turville S; Chataway T; Colella A; Triccas J; Ross TM; Petrovsky N, 2021, Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection, http://dx.doi.org/10.1101/2021.07.03.451026
    Preprints | 2021
    Loo L; Waller M; Cole A; Stella AO; Moreno C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddique R; Mackay J; Turville S; Hesselson D; Neely G, 2021, LRRC15 suppresses SARS-CoV-2 infection and controls collagen production, http://dx.doi.org/10.1101/2021.11.09.467981
    Preprints | 2021
    Shen Y; Freeman JA; Holland J; Solterbeck A; Naidu K; Soosapilla A; Downe P; Tang C; Kerridge I; Wallman L; Van Bilsen N; Milogiannakis V; Akerman A; Martins Costa Gomes G; Sandgren K; Cunningham AL; Turville S; Mulligan SP, 2021, COVID-19 Vaccine Failure in Chronic Lymphocytic Leukemia and Monoclonal B-Lymphocytosis; Humoral and Cellular Immunity, http://dx.doi.org/10.1101/2021.10.28.21265549
    Preprints | 2020
    Ashhurst AS; Tang AH; Fajtová P; Yoon M; Aggarwal A; Stoye A; Larance M; Beretta L; Drelich A; Skinner D; Li L; Meek TD; McKerrow JH; Hook V; Tseng C-TK; Turville S; Gerwick WH; O'Donoghue AJ; Payne RJ, 2020, Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L., http://dx.doi.org/10.1101/2020.12.23.424111
    Preprints | 2020
    Bull R; Abayasingam A; Balachandran H; Agapiou D; Rodrigo C; Keoshkerian E; Li H; Brasher N; Christ D; Rouet R; Burnett D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Brilot F; Mina M; Post J; Hudson B; Gilroy N; Dwyer D; Sasson S; Tea F; Pilli D; Tedla N; Lloyd A; Martinello M, 2020, Long-term persistence of neutralizing memory B cells in SARS-CoV-2, http://dx.doi.org/10.21203/rs.3.rs-92527/v1
    Preprints | 2020
    Counoupas C; Johansen M; Stella A; Nguyen D; Ferguson A; Aggarwal A; Bhattacharyya N; Grey A; Patel K; Siddiquee R; Stewart E; Feng C; Hansbro N; Palendira U; Steain M; Saunders B; Low J; Mackay J; Kelleher A; Britton W; Turville S; Hansbro P; Triccas J, 2020, A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice, http://dx.doi.org/10.1101/2020.12.10.419044
    Conference Abstracts | 2020
    Klemm V; Czuba-Wojnilowicz EI; Cortez-Jugo C; Turville SG; Caruso F; Kelleher AD; Ahlenstiel CL, 2020, 'Delivering Epigenetic Silencing Sirna to the Nucleus of Hiv-1 Infected Primary Activated Cd4+T-Cells via Nanoparticle System', in MOLECULAR THERAPY, CELL PRESS, ELECTR NETWORK, Vol. 28, pp. 468 - 469, presented at 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, ELECTR NETWORK, 12 May 2020 - 15 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530089302176&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2020
    Lau D; Walsh J; Dickson C; Tuckwell A; Stear J; Hunter D; Bhumkar A; Shah V; Turville S; Sierecki E; Gambin Y; Böcking T; Jacques D, 2020, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, http://dx.doi.org/10.1101/2020.11.13.382242
    Preprints | 2020
    Norman A; Franck C; Christie M; Hawkins P; Patel K; Ashhurst A; Aggarwal A; Low J; Siddiquee R; Ashley C; Steain M; Triccas J; Turville S; Mackay J; Passioura T; Payne R, 2020, Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display, http://dx.doi.org/10.1101/2020.12.22.424069
    Conference Abstracts | 2016
    Xu Y; Bailey M; Phetsouphanh C; Harvey R; Turville S; Aggarwal A; Wong A; Suzuki K; Graff-Dubois S; Autran B; Moris A; Munier ML; Koelsch K; Kent S; Zaunders J; Kelleher A, 2016, 'Accumulation of follicular T Helper (Tfh) cells, despite preferential infection, allows establishment of a large and unexpected viral reservoir during HIV infection', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 264 - 264, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400533&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Tong WWY; Turville S; Roberts J; Zaunders J; Jin F; Poynten IM; Hillman RJ; Grulich AE; Kelleher AD; Carr A, 2015, 'T-CELLS IN THE ANAL MUCOSA OF MEN WITH HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS', in SEXUALLY TRANSMITTED INFECTIONS, BMJ PUBLISHING GROUP, Vol. 91, pp. A168 - A168, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000416106400440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2005
    Cunningham A; Wilkinson J; Turville S; Bosnjak L; Dable J; Lai J; Nicolle M, 2005, 'Interaction of human epithelial dendritic cells with HIV and Herpes Simplex virus', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 387 - 388, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700127&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints |
    Abayasingam A; Balachandran H; Agapiou D; Rodrigo C; Keoshkerian E; Li H; Brasher N; Christ D; Rouet R; Burnett D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson S; Tea F; Pilli D; Tedla N; Lloyd AR; Martinello M; Bull RA; Group COSINS, Long-Term Persistence of Neutralizing Memory B Cells in SARS-CoV-2, http://dx.doi.org/10.2139/ssrn.3732365
    Preprints |
    Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Yeang M; Jean T; Foster C; Hoppe AC; Munier ML; Darley DR; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, SARS-CoV-2 Omicron BA.5: Evolving Tropism and Evasion of Potent Humoral Responses and Resistance to Clinical Immunotherapeutics Relative to Viral Variants of Concern, http://dx.doi.org/10.2139/ssrn.4157473
    Preprints |
    Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson S; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer D; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, Maintenance of Broad Neutralising Antibodies and Memory B Cells 12 Months Post-Infection Is Predicted by SARS-CoV-2 Specific CD4+ T Cell Responses, http://dx.doi.org/10.2139/ssrn.3920641
    Preprints |
    Wong AKH; Mathivanan V; Di Giallonardo F; Ahlenstiel C; Turville SG, A Molecular Basis for the Increased Transmission of Ebolavirus in Recent Outbreaks, http://dx.doi.org/10.2139/ssrn.3507710

(CIA) Stuart Turville

2017 NHMRC Project Grant APP1125569

Resolving Human Immunodeficiency Virus (HIV) transmission

 

(CIB) Stuart Turville

2017 NHMRC Project Grant APP1128012

Solving delivery of gene therapy for control of Human Immunodeficiency Virus infection

 

(CIB) Stuart Turville

2016 NHMRC Project Grant APP1128012APP1100771

Discovery and mechanisms of host cell factors in HIV uncoating

 

My Research Supervision

One Honours and four PhD students