Associate Professor Stuart Grant Turville
Senior Research Fellow

Associate Professor Stuart Grant Turville

BSc (Hons I), PhD

medicine-health
The Kirby Institute

The overall goal of my present research work at the Kirby Institute is two-fold. Firstly to define the basic mechanisms of HIV spread, from tracking entry and fusion of single HIV virions through to the more logistically challenging task of tracking viral spread through cell-cell contact.  To date our laboratory is one of only a few laboratories worldwide that can image HIV spread in live HIV infected primary cell types (see image below to observe HIV (white) being lauched by cellular filopodia (red)).Image result for HIV filopodia

The second component of my laboratory is currently involved and actively collaborating with research groups involved in using gene therapy for a treatment of a range of chronic diseases including HIV. Indeed a functional cure for HIV may lie in gene therapy. For instance, functional removal of human genes that HIV needs or attacking the viral genes directly, all represent ways to silence the viral reservoir in the long term. Whilst there are many approaches that work in cell line models, the present limitation to this approach is gene delivery. For instance the cells of the immune system that HIV attacks are unfortunately very difficult to deliver genes to. The broad aim of this project is to systematically determine the best protocol for gene delivery by using different combinations of viral proteins.

We are actively looking for capable honours, masters and PhD students who have a strong interest in the intersection of virology and cellular biology to undertake NHMRC funded projects.

 

 

Mobile
043 220 8645
Phone
+61 (02) 9385 0462
Location
Presently Located The Kirby Institute, UNSW Australia Office 529 Level 5 Wallace Wurth Building, UNSW, Sydney NSW 2052

Publications

  • Book Chapters | 2019
    Associate Professor Stuart Grant Turville
    Ognenovska K; Klemm V; Ledger S; Turville S; Symonds G; D. Kelleher A; L. Ahlenstiel C, 2019, 'Mechanisms for Controlling HIV-1 Infection: A Gene Therapy Approach', in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders, IntechOpen, http://dx.doi.org/10.5772/intechopen.79669
    Book Chapters | 2018
    Associate Professor Stuart Grant Turville
    Ognenovska K; Klemm V; Ledger S; Turville S; Symonds G; Kelleher A; Ahlenstiel CL, 2018, 'Mechanisms for Controlling HIV-1 infection: a Gene Therapy Approach', in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders, http://dx.doi.org/10.5772/intechopen.72962
    Book Chapters | 2008
    Associate Professor Stuart Grant Turville
    Vachot L; Turville SG; Trapp S; Peretti S; Morrow G; Frank I; Pope M, 2008, 'Sleeping with the Enemy: The Insidious Relationship between Dendritic Cells and Immunodeficiency Viruses', in Handbook of Dendritic Cells, pp. 773 - 811, http://dx.doi.org/10.1002/9783527619696.ch38
    Book Chapters | 2007
    Associate Professor Stuart Grant Turville
    Cunningham AL; Wilkinson J; Turville S; Pope M, 2007, 'Binding and uptake of HIV by dendritic cellsand transfer to T lymphocytes: Implicationsfor pathogenesis', in The Biology of Dendritic Cells and HIV Infection, pp. 381 - 404, http://dx.doi.org/10.1007/978-0-387-33785-2_10
  • Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Norman A; Franck C; Christie M; Hawkins PME; Patel K; Ashhurst AS; Aggarwal A; Low JKK; Siddiquee R; Ashley CL; Steain M; Triccas JA; Turville S; MacKay JP; Passioura T; Payne RJ, 2021, 'Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display', ACS Central Science, vol. 7, pp. 1001 - 1008, http://dx.doi.org/10.1021/acscentsci.0c01708
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Walker GJ; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs SR; Agapiou D; Bull RA; Stelzer-Braid S; Daly J; Gosbell IB; Hoad VC; Irving DO; Pink JM; Turville S; Kelleher AD; Rawlinson WD, 2021, 'Sars coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays', Viruses, vol. 13, pp. 247 - 247, http://dx.doi.org/10.3390/v13020247
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Böcking T; Jacques DA; Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y, 2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, vol. 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, vol. 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Fichter C; Aggarwal A; Wong AKH; McAllery S; Mathivanan V; Hao B; MacRae H; Churchill MJ; Gorry PR; Roche M; Gray LR; Turville S, 2021, 'Modular Lentiviral Vectors for Highly Efficient Transgene Expression in Resting Immune Cells', Viruses, vol. 13, pp. 1170 - 1170, http://dx.doi.org/10.3390/v13061170
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Rouet R; Mazigi O; Walker GJ; Langley DB; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry JY; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull RA; Turville S; Stewart AG; Goodnow CC; Rawlinson WD; Christ D, 2021, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', mAbs, vol. 13, pp. 1922134, http://dx.doi.org/10.1080/19420862.2021.1922134
    Journal articles | 2021
    Associate Professor Stuart Grant Turville
    Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Fichter C; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffmann M; Pöhlman S; Mazigi O; Christ D; Rockett RJ; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2021, 'SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants', PLoS Medicine, vol. 18, pp. e1003656, http://dx.doi.org/10.1371/journal.pmed.1003656
    Journal articles | 2020
    Associate Professor Stuart Grant Turville
    Van Bockel D; Munier CML; Turville S; Badman SG; Walker G; Stella AO; Aggarwal A; Yeang M; Condylios A; Kelleher AD; Applegate TL; Vallely A; Whiley D; Rawlinson W; Cunningham P; Kaldor J; Guy R, 2020, 'Evaluation of commercially available viral transport medium (VTM) for SARS-CoV-2 inactivation and use in point-of-care (POC) testing', Viruses, vol. 12, pp. 1208 - 1208, http://dx.doi.org/10.3390/v12111208
    Journal articles | 2020
    Associate Professor Stuart Grant Turville
    Stelzer-Braid S; Walker GJ; Aggarwal A; Isaacs SR; Yeang M; Naing Z; Ospina Stella A; Turville SG; Rawlinson WD, 2020, 'Virus isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for diagnostic and research purposes', Pathology, vol. 52, pp. 760 - 763, http://dx.doi.org/10.1016/j.pathol.2020.09.012
    Journal articles | 2020
    Associate Professor Stuart Grant Turville
    Walker GJ; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein LD; Rawlinson W, 2020, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurisation but not cold storage', Journal of Paediatrics and Child Health, vol. 56, pp. 1872 - 1874, http://dx.doi.org/10.1111/jpc.15065
    Journal articles | 2020
    Associate Professor Stuart Grant Turville
    Lau D; Walsh JC; Mousapasandi A; Ariotti N; Shah VB; Turville S; Jacques DA; Böcking T, 2020, 'Self-Assembly of Fluorescent HIV Capsid Spheres for Detection of Capsid Binders', Langmuir, vol. 36, pp. 3624 - 3632, http://dx.doi.org/10.1021/acs.langmuir.0c00103
    Journal articles | 2020
    Associate Professor Stuart Grant Turville
    Walker G; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs S; Agapiou D; Bull R; Stelzer-Braid S; Daly J; Gosbell I; Hoad V; Irving D; Pink J; Turville S; Kelleher A; Rawlinson W, 2020, 'SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays', , http://dx.doi.org/10.1101/2020.12.07.20245696
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Bertram KM; Tong O; Royle C; Turville SG; Nasr N; Cunningham AL; Harman AN, 2019, 'Manipulation of mononuclear phagocytes by HIV: Implications for early transmission events', Frontiers in Immunology, vol. 10, http://dx.doi.org/10.3389/fimmu.2019.02263
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Marquez CL; Lau D; Walsh J; Faysal KMR; Parker MW; Turville SG; Bocking T, 2019, 'Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro', BIO-PROTOCOL, vol. 9, http://dx.doi.org/10.21769/BioProtoc.3297
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Rhodes JW; Tong O; Harman AN; Turville SG, 2019, 'Human dendritic cell subsets, ontogeny, and impact on HIV infection', Frontiers in Immunology, vol. 10, pp. 1088, http://dx.doi.org/10.3389/fimmu.2019.01088
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Ahlenstiel CL; Turville SG, 2019, 'Delivery of gene therapy to resting immune cells for an HIV cure', Current Opinion in HIV and AIDS, vol. 14, pp. 129 - 136, http://dx.doi.org/10.1097/COH.0000000000000531
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Lau D; Walsh JC; Peng W; Shah VB; Turville S; Jacques DA; Böcking T, 2019, 'Fluorescence Biosensor for Real-Time Interaction Dynamics of Host Proteins with HIV-1 Capsid Tubes', ACS Applied Materials and Interfaces, vol. 11, pp. 34586 - 34594, http://dx.doi.org/10.1021/acsami.9b08521
    Journal articles | 2019
    Associate Professor Stuart Grant Turville
    Hu W; Cai Y; Zhu Y; Li F; Stella AO; Tebas P; Mounzer K; Kostman J; Turville S; Montaner L, 2019, 'Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle', Journal of Virus Eradication, vol. 5, pp. 55 - 56, http://dx.doi.org/10.1016/s2055-6640(20)30221-1
    Journal articles | 2018
    Associate Professor Stuart Grant Turville
    Stella AO; Turville S, 2018, 'All-round manipulation of the actin cytoskeleton by HIV', Viruses, vol. 10, http://dx.doi.org/10.3390/v10020063
    Journal articles | 2018
    Associate Professor Stuart Grant Turville
    Márquez CL; Lau D; Walsh J; Shah V; McGuinness C; Wong A; Aggarwal A; Parker MW; Jacques DA; Turville S; Böcking T, 2018, 'Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.34772
    Journal articles | 2018
    Associate Professor Stuart Grant Turville
    Ledger S; Howe A; Turville S; Aggarwal A; Savkovic B; Ong A; Wolstein O; Boyd M; Millington M; Gorry PR; Murray JM; Symonds G, 2018, 'Analysis and dissociation of anti-HIV effects of shRNA to CCR5 and the fusion inhibitor C46', Journal of Gene Medicine, vol. 20, http://dx.doi.org/10.1002/jgm.3006
    Journal articles | 2018
    Associate Professor Stuart Grant Turville
    Turville S; Kelleher A, 2018, 'Obituary: Remembering Professor David Cooper', Retrovirology, vol. 15, pp. 40, http://dx.doi.org/10.1186/s12977-018-0418-1
    Journal articles | 2017
    Associate Professor Stuart Grant Turville
    Aggarwal A; Hitchen TL; Ootes L; McAllery S; Wong A; Nguyen K; McCluskey A; Robinson PJ; Turville SG, 2017, 'HIV infection is influenced by dynamin at 3 independent points in the viral life cycle', Traffic, vol. 18, pp. 392 - 410, http://dx.doi.org/10.1111/tra.12481
    Journal articles | 2017
    Associate Professor Stuart Grant Turville
    Xu Y; Phetsouphanh C; Suzuki K; Aggrawal A; Graff-Dubois S; Roche M; Bailey M; Alcantara S; Cashin K; Sivasubramaniam R; Koelsch KK; Autran B; Harvey R; Gorry PR; Moris A; Cooper DA; Turville S; Kent SJ; Kelleher AD; Zaunders J, 2017, 'HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells', Frontiers in Immunology, vol. 8, http://dx.doi.org/10.3389/fimmu.2017.00376
    Journal articles | 2017
    Associate Professor Stuart Grant Turville
    Aggarwal A; Turville SG, 2017, 'Resolving the Sites of HIV Entry: Dynamin Networks Hold the Key', Journal of Cell Signaling, vol. 02, http://dx.doi.org/10.4172/2576-1471.1000173
    Journal articles | 2016
    Associate Professor Stuart Grant Turville
    Ng WC; Londrigan SL; Nasr N; Cunningham AL; Turville S; Brooks AG; Reading PC, 2016, 'The C-type lectin langerin functions as a receptor for attachment and infectious entry of influenza A virus', Journal of Virology, vol. 90, pp. 206 - 221, http://dx.doi.org/10.1128/JVI.01447-15
    Journal articles | 2016
    Associate Professor Stuart Grant Turville
    McAllery SA; Ahlenstiel CL; Suzuki K; Symonds GP; Kelleher AD; Turville SG, 2016, 'The feasibility of incorporating Vpx into lentiviral gene therapy vectors', Molecular Therapy - Methods and Clinical Development, vol. 3, pp. 16066, http://dx.doi.org/10.1038/mtm.2016.66
    Journal articles | 2015
    Associate Professor Stuart Grant Turville
    Jayathunge PHM; McBride WJH; Maclaren D; Kaldor J; Vallely A; Turville S, 2015, 'Male circumcision and HIV transmission; What do we know?', Open AIDS Journal, vol. 8, pp. 31 - 44, http://dx.doi.org/10.2174/1874613601408010031
    Journal articles | 2015
    Associate Professor Stuart Grant Turville
    Ahlenstiel C; Mendez C; Lim STH; Marks K; Turville S; Cooper DA; Kelleher AD; Suzuki K, 2015, 'Novel RNA duplex locks HIV-1 in a latent state via chromatin-mediated transcriptional silencing', Molecular Therapy - Nucleic Acids, vol. 4, pp. e261, http://dx.doi.org/10.1038/mtna.2015.31
    Journal articles | 2015
    Associate Professor Stuart Grant Turville
    Tong WWY; Turville S; Roberts J; Zaunders J; Jin F; Poynten IM; Hillman RJ; Grulich AE; Kelleher AD; Carr A, 2015, 'P10.10 T-cells in the anal mucosa of men with high-grade squamous intraepithelial lesions', Sexually Transmitted Infections, vol. 91, pp. A168.2 - A168, http://dx.doi.org/10.1136/sextrans-2015-052270.438
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Turville SG; Nasr N; Lai J; Botting RA; Mercier SK; Harman AN; Kim M; Centre RJ; Domagala T; Gorry PR; Olbourne N; Cunningham AL, 2014, 'Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerin', J Immunol, vol. 193, pp. 2554 - 2564, http://dx.doi.org/10.4049/jimmunol.1400630
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Gray LR; Turville SG; HItchen TL; Cheng WJ; Ellett AM; Salimi H; Roche MJ; Wesselingh SL; Gorry PR; Churchill MJ, 2014, 'HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0090620
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Eyre NS; Fiches GN; Aloia AL; Helbig KJ; McCartney EM; McErlean CSP; Li K; Aggarwal A; Turville SG; Beard MR, 2014, 'Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection', Journal of Virology, vol. 88, pp. 3636 - 3652, http://dx.doi.org/10.1128/JVI.02490-13
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Turville S, 2014, 'Blocking of HIV entry through CD44-hyaluronic acid interactions', Immunology and Cell Biology, vol. 92, pp. 735 - 736, http://dx.doi.org/10.1038/icb.2014.66
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Nasr N; Harman A; Turville S; Cunningham AL, 2014, 'HIV infection of dendritic cells', Methods in Molecular Biology, vol. 1087, pp. 221 - 232, http://dx.doi.org/10.1007/978-1-62703-670-2-18
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Gray LR; Turville SG; Hitchen TL; Cheng WJ; Ellett AM, 2014, 'Correction: HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles (PLoS ONE (2014) 9, 2, (e90620) DOI:10.1371/journal.pone.0090620)', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0093417
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Aggarwal A; Turville SG, 2014, 'Imaging HIV entry and egress', Microbiology Australia
    Journal articles | 2014
    Associate Professor Stuart Grant Turville
    Nasr N; Harman A; Turville S; Cunningham AL, 2014, 'HIV infection of dendritic cells', Methods in Molecular Biology, vol. 1087, pp. 221 - 232, http://dx.doi.org/10.1007/978-1-62703-670-2_18
    Journal articles | 2013
    Associate Professor Stuart Grant Turville
    Mercier SK; Donaghy H; Botting RA; Turville SG; Harman AN; Nasr N; Ji H; Kusebauch U; Mendoza L; Shteynberg D; Sandgren K; Simpson RJ; Moritz RL; Cunningham AL, 2013, 'The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes', PLoS Pathogens, vol. 9, http://dx.doi.org/10.1371/journal.ppat.1003700
    Journal articles | 2013
    Associate Professor Stuart Grant Turville
    2013, 'The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0062196
    Journal articles | 2013
    Associate Professor Stuart Grant Turville
    Aggarwal A; Mcallery S; Turville S, 2013, 'Revising the role of myeloid cells in HIV pathogenesis', Current HIV/AIDS Reports, vol. 10, pp. 3 - 11, http://dx.doi.org/10.1007/s11904-012-0149-1
    Journal articles | 2013
    Associate Professor Stuart Grant Turville
    Mercier SK; Donaghy H; Botting RA; Turville SG; Harman AN; Nasr N; Ji H; Kusebauch U; Mendoza L; Shteynberg D; Sandgren K; Simpson RJ; Moritz RL; Cunningham AL, 2013, 'Correction: The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes', PLoS Pathogens, vol. 9, http://dx.doi.org/10.1371/annotation/059beb14-db84-4836-9fef-ec351946025a
    Journal articles | 2012
    Associate Professor Stuart Grant Turville
    Purcell DJ; Cunningham AL; Turville S; Tachedjian TG; Landay A, 2012, 'Biology of Mucosally Transmitted Sexual Infection-Translating the Basic Science into Novel HIV Intervention: A Workshop Summary', AIDS Research and Human Retroviruses, vol. 28, pp. 1389 - 1396, http://dx.doi.org/10.1089/aid.2012.0276
    Journal articles | 2012
    Associate Professor Stuart Grant Turville
    Nasr N; Maddocks S; Turville S; Harman AN; Woolger N; Helbig KJ; Wilkinson J; Bye CR; Wright TK; Rambukwelle D; Donaghy H; Beard MR; Cunningham AL, 2012, 'HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.', Blood, vol. 120, pp. 778 - 788, http://dx.doi.org/10.1182/blood-2012-01-407395
    Journal articles | 2012
    Associate Professor Stuart Grant Turville
    Aggarwal A; Iemma T; Shih I; Newsome TP; Mcallery S; Cunningham A; Turville S, 2012, 'Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells', PLoS Pathogens, vol. 8, pp. e1002762, http://dx.doi.org/10.1371/journal.ppat.1002762
    Journal articles | 2012
    Associate Professor Stuart Grant Turville
    Gray L; Tachedjian G; Ellett A; Roche M; Brew B; Turville S; Wesselingh S; Gorry P; Churchill M, 2012, 'Reduced Effectiveness of the NRTIs d4T and AZT in Astrocytes: Implications for Neuro-cART', JOURNAL OF NEUROVIROLOGY, vol. 18, pp. 42 - 43, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800089&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2011
    Associate Professor Stuart Grant Turville
    Keller CW; Fokken C; Turville SG; Lünemann A; Schmidt J; Münz C; Lünemann JD, 2011, 'TNF-α induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells', Journal of Biological Chemistry, vol. 286, pp. 3970 - 3980, http://dx.doi.org/10.1074/jbc.M110.159392
    Journal articles | 2011
    Associate Professor Stuart Grant Turville
    Londrigan SL; Turville SG; Tate MD; Deng YM; Brooks AG; Reading PC, 2011, 'N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN', Journal of Virology, vol. 85, pp. 2990 - 3000, http://dx.doi.org/10.1128/JVI.01705-10
    Journal articles | 2011
    Associate Professor Stuart Grant Turville
    Harman AN; Lai J; Turville S; Samarajiwa S; Gray L; Marsden V; Mercier S; Jones K; Nasr N; Rustagi A; Cumming H; Donaghy H; Mak J; Gale M; Churchill M; Hertzog P; Cunningham AL, 2011, 'HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production', Blood, vol. 118, pp. 298 - 308, http://dx.doi.org/10.1182/blood-2010-07-297721
    Journal articles | 2011
    Associate Professor Stuart Grant Turville
    Harman AN; Lai J; Turville S, 2011, 'HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production (Blood (2011) 118, 2 (298-308))', Blood, vol. 118, pp. 6992, http://dx.doi.org/10.1182/blood-2011-10-384719
    Journal articles | 2010
    Associate Professor Stuart Grant Turville
    Cunningham AL; Donaghy H; Harman AN; Kim M; Turville SG, 2010, 'Manipulation of dendritic cell function by viruses', Current Opinion in Microbiology, vol. 13, pp. 524 - 529, http://dx.doi.org/10.1016/j.mib.2010.06.002
    Journal articles | 2010
    Associate Professor Stuart Grant Turville
    Cunningham AL; Abendroth A; Jones C; Nasr N; Turville S, 2010, 'Viruses and Langerhans cells', Immunology and Cell Biology, vol. 88, pp. 416 - 423, http://dx.doi.org/10.1038/icb.2010.42
    Journal articles | 2009
    Associate Professor Stuart Grant Turville
    Trapp S; Derby NR; Singer R; Shaw A; Williams VG; Turville SG; Bess JW; Lifson JD; Robbiani M, 2009, 'Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G', Journal of Virology, vol. 83, pp. 884 - 895, http://dx.doi.org/10.1128/JVI.00023-08
    Journal articles | 2009
    Associate Professor Stuart Grant Turville
    Harman AN; Kraus M; Bye CR; Byth K; Turville SG; Tang O; Mercier SK; Nasr N; Stern JL; Slobedman B; Driessen C; Cunningham AL, 2009, 'HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase', Blood, vol. 114, pp. 85 - 94, http://dx.doi.org/10.1182/blood-2008-12-194845
    Journal articles | 2009
    Associate Professor Stuart Grant Turville
    Lai J; Bernhard OK; Turville SG; Harman AN; Wilkinson J; Cunningham AL, 2009, 'Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1', Journal of Biological Chemistry, vol. 284, pp. 11027 - 11038, http://dx.doi.org/10.1074/jbc.M809698200
    Journal articles | 2008
    Associate Professor Stuart Grant Turville
    Turville SG; Aravantinou M; Miller T; Kenney J; Teitelbaum A; Hu L; Chudolij A; Zydowsky TM; Piatak M; Bess JW; Lifson JD; Blanchard J; Gettie A; Robbiani M, 2008, 'Efficacy of carraguard®-based microbicides in vivo despite variable in vitro activity', PLoS ONE, vol. 3, http://dx.doi.org/10.1371/journal.pone.0003162
    Journal articles | 2008
    Associate Professor Stuart Grant Turville
    Frank I; Stössel H; Gettie A; Turville SG; Bess JW; Lifson JD; Sivin I; Romani N; Robbiani M, 2008, 'A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells', Journal of Virology, vol. 82, pp. 5329 - 5339, http://dx.doi.org/10.1128/JVI.01987-07
    Journal articles | 2008
    Associate Professor Stuart Grant Turville
    Turville SG; Aravantinou M; Stössel H; Romani N; Robbiani M, 2008, 'Resolution of de novo HIV production and trafficking in immature dendritic cells', Nature Methods, vol. 5, pp. 75 - 85, http://dx.doi.org/10.1038/nmeth1137
    Journal articles | 2008
    Associate Professor Stuart Grant Turville
    Schweizer A; Rusert P; Berlinger L; Ruprecht CR; Mann A; Corthésy S; Turville SG; Aravantinou M; Fischer M; Robbiani M; Amstutz P; Trkola A, 2008, 'CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics', PLoS Pathogens, vol. 4, http://dx.doi.org/10.1371/journal.ppat.1000109
    Journal articles | 2008
    Associate Professor Stuart Grant Turville
    Keller CW; Lee M; Turville SG; Bähr M; Münz C; Lünemann JD; Schmidt J, 2008, 'Akkumulation von beta-Amyloid im Skelettmuskel: Zytokin-induzierte Modulation von Makroautophagie', Aktuelle Neurologie, vol. 35, http://dx.doi.org/10.1055/s-0028-1086702
    Journal articles | 2007
    Associate Professor Stuart Grant Turville
    Fernández-Romero JA; Thorn M; Turville SG; Titchen K; Sudol K; Li J; Miller T; Robbiani M; Maguire RA; Buckheit RW; Hartman TL; Phillips DM, 2007, 'Carrageenan/MIV-150 (PC-815), a combination microbicide', Sexually Transmitted Diseases, vol. 34, pp. 9 - 14, http://dx.doi.org/10.1097/01.olq.0000223287.46097.4b
    Journal articles | 2006
    Associate Professor Stuart Grant Turville
    Lynch GW; Turville S; Carter B; Sloane AJ; Chan A; Muljadi N; Li S; Low L; Armati P; Raison R; Zoellner H; Williamson P; Cunningham A; Church WB, 2006, 'Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: Resolution of a novel CD4 isoform', Immunology and Cell Biology, vol. 84, pp. 154 - 165, http://dx.doi.org/10.1111/j.1440-1711.2005.01403.x
    Journal articles | 2006
    Associate Professor Stuart Grant Turville
    Trapp S; Turville SG; Robbiani M, 2006, 'Slamming the door on unwanted guests: Why preemptive strikes at the mucosa may be the best strategy against HIV', Journal of Leukocyte Biology, vol. 80, pp. 1076 - 1083, http://dx.doi.org/10.1189/jlb.0206121
    Journal articles | 2006
    Associate Professor Stuart Grant Turville
    Turville SG; Peretti S; Pope M, 2006, 'Lymphocyte-dendritic cell interactions and mucosal acquisition of SIV/HIV infection.', Curr Opin HIV AIDS, vol. 1, pp. 3 - 9, http://dx.doi.org/10.1097/01.COH.0000194109.14601.20
    Journal articles | 2005
    Associate Professor Stuart Grant Turville
    Turville SG; Vermeire K; Balzarini J; Schols D, 2005, 'Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer', Journal of Virology, vol. 79, pp. 13519 - 13527, http://dx.doi.org/10.1128/JVI.79.21.13519-13527.2005
    Journal articles | 2005
    Associate Professor Stuart Grant Turville
    Sloane AJ; Raso V; Dimitrov DS; Xiao X; Deo S; Muljadi N; Restuccia D; Turville S; Kearney C; Broder CC; Zoellner H; Cunningham AL; Bendall L; Lynch GW, 2005, 'Marked structural and functional heterogeneity in CXCR4: Separation of HIV-1 and SDF-1α responses', Immunology and Cell Biology, vol. 83, pp. 129 - 143, http://dx.doi.org/10.1111/j.1440-1711.2004.01304.x
    Journal articles | 2004
    Associate Professor Stuart Grant Turville
    Turville SG; Santos JJ; Frank I; Cameron PU; Wilkinson J; Miranda-Saksena M; Dable J; Stõssel H; Romani N; Piatak M; Lifson JD; Pope M; Cunningham AL, 2004, 'Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells', Blood, vol. 103, pp. 2170 - 2179, http://dx.doi.org/10.1182/blood-2003-09-3129
    Journal articles | 2003
    Associate Professor Stuart Grant Turville
    Lynch GW; Slaytor EK; Elliott FD; Saurajen A; Turville SG; Sloane AJ; Cameron PU; Cunningham AL; Halliday GM, 2003, 'CD4 is expressed by epidermal Langerhans' cells predominantly as covalent dimers', Experimental Dermatology, vol. 12, pp. 700 - 711, http://dx.doi.org/10.1034/j.1600-0625.2003.00078.x
    Journal articles | 2003
    Associate Professor Stuart Grant Turville
    Turville S; Wilkinson J; Cameron P; Dable J; Cunningham AL, 2003, 'The role of dendritic cell C-type lectin receptors in HIV pathogenesis', Journal of Leukocyte Biology, vol. 74, pp. 710 - 718, http://dx.doi.org/10.1189/jlb.0503208
    Journal articles | 2003
    Associate Professor Stuart Grant Turville
    Kedzierska K; Crowe SM; Turville S; Cunningham AL, 2003, 'The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages', Reviews in Medical Virology, vol. 13, pp. 39 - 56, http://dx.doi.org/10.1002/rmv.369
    Journal articles | 2002
    Associate Professor Stuart Grant Turville
    Turville SG; Cameron PU; Handley A; Lin G; Pöhlmann S; Doms RW; Cunningham AL, 2002, 'Diversity of receptors binding HIV on dendritic cell subsets', Nature Immunology, vol. 3, pp. 975 - 983, http://dx.doi.org/10.1038/ni841
    Journal articles | 2002
    Associate Professor Stuart Grant Turville
    Turville SG; Cameron PU; Derek H; Cunningham AL, 2002, 'C-type lectin-HIV attachment on dendritic cells:Innate immune recognition and processing or mediators of HIV transmission?', Trends in Glycoscience and Glycotechnology, vol. 14, pp. 255 - 271, http://dx.doi.org/10.4052/tigg.14.255
    Journal articles | 2001
    Associate Professor Stuart Grant Turville
    Turville SG; Arthos J; MacDonald K; Lynch G; Naif H; Clark G; Hart D; Cunningham AL, 2001, 'HIV gp120 receptors on human dendritic cells', Blood, vol. 98, pp. 2482 - 2488, http://dx.doi.org/10.1182/blood.V98.8.2482
    Journal articles | 2000
    Associate Professor Stuart Grant Turville
    Turville SG; Cameron PU; Arthos J; MacDonald K; Clark G; Hart D; Cunningham AL, 2000, 'Sweet symphony', New Scientist, vol. 166, pp. 11, http://dx.doi.org/10.1016/S1386-6532(01)00194-9
    Journal articles |
    Associate Professor Stuart Grant Turville
    Walker GJ; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein LD; Rawlinson W, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage', , http://dx.doi.org/10.1101/2020.06.18.20134395
    Journal articles |
    Associate Professor Stuart Grant Turville
    Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffman M; Pöhlmann S; Dwyer DE; Rockett R; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 'SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants', , http://dx.doi.org/10.1101/2020.12.19.20248567
    Journal articles |
    Associate Professor Stuart Grant Turville
    Capraro A; Wong SL; Adhikari A; Allan KM; Patel HR; Zhong L; Raftery M; Jaffe A; Yeang M; Aggarwal A; Wu L; Pandzic E; Whan RM; Turville S; Vittorio O; Bull RA; Kaakoush N; Rawlinson WD; Tedla N; Vafaee F; Waters SA, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453
  • Conference Abstracts | 2020
    Associate Professor Stuart Grant Turville
    Klemm V; Czuba-Wojnilowicz EI; Cortez-Jugo C; Turville SG; Caruso F; Kelleher AD; Ahlenstiel CL, 2020, 'Delivering Epigenetic Silencing Sirna to the Nucleus of Hiv-1 Infected Primary Activated Cd4+T-Cells via Nanoparticle System', in MOLECULAR THERAPY, CELL PRESS, ELECTR NETWORK, Vol. 28, pp. 468 - 469, presented at 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, ELECTR NETWORK, 12 May 2020 - 15 May 2020, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530089302176&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Associate Professor Stuart Grant Turville
    Xu Y; Bailey M; Phetsouphanh C; Harvey R; Turville S; Aggarwal A; Wong A; Suzuki K; Graff-Dubois S; Autran B; Moris A; Munier ML; Koelsch K; Kent S; Zaunders J; Kelleher A, 2016, 'Accumulation of follicular T Helper (Tfh) cells, despite preferential infection, allows establishment of a large and unexpected viral reservoir during HIV infection', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 264 - 264, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400533&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Stuart Grant Turville
    Tong WWY; Turville S; Roberts J; Zaunders J; Jin F; Poynten IM; Hillman RJ; Grulich AE; Kelleher AD; Carr A, 2015, 'T-CELLS IN THE ANAL MUCOSA OF MEN WITH HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS', in SEXUALLY TRANSMITTED INFECTIONS, BMJ PUBLISHING GROUP, Vol. 91, pp. A168 - A168, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000416106400440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2005
    Associate Professor Stuart Grant Turville
    Cunningham A; Wilkinson J; Turville S; Bosnjak L; Dable J; Lai J; Nicolle M, 2005, 'Interaction of human epithelial dendritic cells with HIV and Herpes Simplex virus', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, Melbourne, AUSTRALIA, pp. 387 - 388, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, AUSTRALIA, 29 November 2005 - 02 December 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700127&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Awards

Grants

(CIA) Stuart Turville

2017 NHMRC Project Grant APP1125569

Resolving Human Immunodeficiency Virus (HIV) transmission

 

(CIB) Stuart Turville

2017 NHMRC Project Grant APP1128012

Solving delivery of gene therapy for control of Human Immunodeficiency Virus infection

 

(CIB) Stuart Turville

2016 NHMRC Project Grant APP1128012APP1100771

Discovery and mechanisms of host cell factors in HIV uncoating

 

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