Conjoint Professor

Professor Susan Clark

medicine-health
St Vincent's Clinical School

Publications

  • Book Chapters | 2016
    Professor Susan Clark
    Sibbritt T; Shafik A; Clark SJ; Preiss T, 2016, 'Nucleotide-Level Profiling of m⁵C RNA Methylation.', in Post-Transcriptional Gene Regulation, pp. 269 - 284, http://dx.doi.org/10.1007/978-1-4939-3067-8_16
    Book Chapters | 2011
    Professor Susan Clark
    Guerrero-Bosagna CM; Clark SJ, 2011, 'We are what we eat: how nutritional compounds such as isoflavones shape our epigenome', in Niculescu MD; Haggarty P (ed.), Nutrition in Epigenetics, Wiley-Blackwell, Oxford, UK, pp. 249 - 261, http://dx.doi.org/10.1002/9780470959824.ch15
    Book Chapters | 2011
    Professor Susan Clark
    Coolen MW; Clark SJ, 2011, 'Genome-wide DNA Methylation Analysis', in Craig JM; Wong NC (ed.), EPIGENETICS: A REFERENCE MANUAL, CAISTER ACADEMIC PRESS, pp. 371 - 392, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293148200022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Books | 2011
    Professor Susan Clark
    Coolen MW; Clark SJ, 2011, Epigenetics: A Reference Manual, Original, Caister Academic Press, UK, http://www.horizonpress.com/epigenetics
    Book Chapters | 2004
    Professor Susan Clark
    Clark SJ, 2004, 'Studying mammalian DNA methylation: Bisulfite modification', in DNA Methylation: Approaches, Methods, and Applications, pp. 53 - 64, http://dx.doi.org/10.1201/9780203487013
    Book Chapters | 2003
    Professor Susan Clark
    Clark SJ; Millar DS; Molloy P, 2003, 'Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival Tissue Samples', in Prostate Cancer Methods and Protocols, pp. 219 - 240, http://dx.doi.org/10.1385/1-59259-372-0:219
  • Journal articles | 2021
    Professor Susan Clark
    Giles KA; Gould CM; Achinger-Kawecka J; Page SG; Kafer GR; Rogers S; Luu PL; Cesare AJ; Clark SJ; Taberlay PC, 2021, 'BRG1 knockdown inhibits proliferation through multiple cellular pathways in prostate cancer', Clinical Epigenetics, vol. 13, http://dx.doi.org/10.1186/s13148-021-01023-7
    Journal articles | 2021
    Professor Susan Clark
    Stirzaker C; Skvortsova K; Clark SJ, 2021, 'Epigenetic changes during tumour development – functional epigenetics study', Pathology, vol. 53, pp. S10 - S11, http://dx.doi.org/10.1016/j.pathol.2021.05.040
    Journal articles | 2020
    Professor Susan Clark
    Lam D; Luu PL; Song JZ; Qu W; Risbridger GP; Lawrence MG; Lu J; Trau M; Korbie D; Clark SJ; Pidsley R; Stirzaker C, 2020, 'Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels', Clinical Epigenetics, vol. 12, pp. 90, http://dx.doi.org/10.1186/s13148-020-00880-y
    Journal articles | 2020
    Professor Susan Clark
    Achinger-Kawecka J; Valdes-Mora F; Luu PL; Giles KA; Caldon CE; Qu W; Nair S; Soto S; Locke WJ; Yeo-Teh NS; Gould CM; Du Q; Smith GC; Ramos IR; Fernandez KF; Hoon DS; Gee JMW; Stirzaker C; Clark SJ, 2020, 'Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-019-14098-x
    Journal articles | 2020
    Professor Susan Clark
    Schumann U; Zhang HN; Sibbritt T; Pan A; Horvath A; Gross S; Clark SJ; Yang L; Preiss T, 2020, 'Multiple links between 5-methylcytosine content of mRNA and translation', BMC Biology, vol. 18, http://dx.doi.org/10.1186/s12915-020-00769-5
    Journal articles | 2020
    Professor Susan Clark
    Green ID; Pinello N; Song R; Lee Q; Halstead JM; Kwok CT; Wong ACH; Nair SS; Clark SJ; Roediger B; Schmitz U; Larance M; Hayashi R; Rasko JEJ; Wong JJL, 2020, 'Macrophage development and activation involve coordinated intron retention in key inflammatory regulators', Nucleic Acids Research, vol. 48, pp. 6513 - 6529, http://dx.doi.org/10.1093/nar/gkaa435
    Journal articles | 2020
    Professor Susan Clark
    Piggin CL; Roden DL; Law AMK; Molloy MP; Krisp C; Swarbrick A; Naylor MJ; Kalyuga M; Kaplan W; Oakes SR; Gallego-Ortega D; Clark SJ; Carroll JS; Bartonicek N; Ormandy CJ, 2020, 'ELF5 modulates the estrogen receptor cistrome in breast cancer', PLoS Genetics, vol. 16, pp. e1008531, http://dx.doi.org/10.1371/journal.pgen.1008531
    Journal articles | 2020
    Professor Susan Clark
    Lawrence MG; Pidsley R; Niranjan B; Papargiris M; Pereira BA; Richards M; Teng L; Norden S; Ryan A; Frydenberg M; Stirzaker C; Taylor RA; Risbridger GP; Clark SJ, 2020, 'Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer', Clinical Epigenetics, vol. 12, pp. 48, http://dx.doi.org/10.1186/s13148-020-00836-2
    Journal articles | 2020
    Professor Susan Clark
    Schmitz U; Shah JS; Dhungel BP; Monteuuis G; Luu PL; Petrova V; Metierre C; Nair SS; Bailey CG; Saunders VA; Turhan AG; White DL; Branford S; Clark SJ; Hughes TP; Wong JJL; Rasko JEJ, 2020, 'Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukaemia patients', Cancers, vol. 12, pp. 1 - 19, http://dx.doi.org/10.3390/cancers12123738
    Journal articles | 2020
    Professor Susan Clark
    Salazar-Roa M; Trakala M; Álvarez-Fernández M; Valdés-Mora F; Zhong C; Muñoz J; Yu Y; Peters TJ; Graña-Castro O; Serrano R; Zapatero-Solana E; Abad M; Bueno MJ; de Cedrón MG; Fernández-Piqueras J; Serrano M; Blasco MA; Wang DZ; Clark SJ; Izpisua-Belmonte JC; Ortega S; Malumbres M, 2020, 'Transient exposure to miR-203 enhances the differentiation capacity of established pluripotent stem cells', EMBO Journal, vol. 39, http://dx.doi.org/10.15252/embj.2019104324
    Journal articles | 2020
    Professor Susan Clark
    Khoury A; Achinger-Kawecka J; Bert SA; Smith GC; French HJ; Luu PL; Peters TJ; Du Q; Parry AJ; Valdes-Mora F; Taberlay PC; Stirzaker C; Statham AL; Clark SJ, 2020, 'Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-019-13753-7
    Journal articles | 2020
    Professor Susan Clark
    Phuc-Loi L; Phuc-Thinh O; Thanh-Phuoc D; Clark SJ, 2020, 'Benchmark study comparing liftover tools for genome conversion of epigenome sequencing data', NAR GENOMICS AND BIOINFORMATICS, vol. 2, http://dx.doi.org/10.1093/nargab/lqaa054
    Journal articles | 2020
    Professor Susan Clark
    Luu P-L; Ong P-T; Loc TTH; Lam D; Pidsley R; Stirzaker C; Clark SJ, 2020, 'MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection.', Bioinformatics, http://dx.doi.org/10.1093/bioinformatics/btaa1060
    Journal articles | 2020
    Professor Susan Clark
    Lam D; Clark S; Stirzaker C; Pidsley R, 2020, 'Advances in prognostic methylation biomarkers for prostate cancer', Cancers, vol. 12, pp. 1 - 39, http://dx.doi.org/10.3390/cancers12102993
    Journal articles | 2020
    Professor Susan Clark
    Stirzaker C; Skvortsova K; Masle-Farquhar E; Goodnow C; Clark SJ, 2020, 'Epigenetic changes during tumour development – Functional epigenetics study', Pathology, vol. 52, pp. S29 - S29, http://dx.doi.org/10.1016/j.pathol.2020.01.121
    Journal articles | 2019
    Professor Susan Clark
    Peters TJ; French HJ; Bradford ST; Pidsley R; Stirzaker C; Varinli H; Nair S; Qu W; Song J; Giles KA; Statham AL; Speirs H; Speed TP; Clark SJ, 2019, 'Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements', Bioinformatics, vol. 35, pp. 560 - 570, http://dx.doi.org/10.1093/bioinformatics/bty675
    Journal articles | 2019
    Professor Susan Clark
    Tarr IS; McCann EP; Benyamin B; Peters TJ; Twine NA; Zhang KY; Zhao Q; Zhang ZH; Rowe DB; Nicholson GA; Bauer D; Clark SJ; Blair IP; Williams KL, 2019, 'Monozygotic twins and triplets discordant for amyotrophic lateral sclerosis display differential methylation and gene expression', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-44765-4
    Journal articles | 2019
    Professor Susan Clark
    Bradford ST; Nair SS; Statham AL; van Dijk SJ; Peters TJ; Anwar F; French HJ; von Martels JZH; Sutcliffe B; Maddugoda MP; Peranec M; Varinli H; Arnoldy R; Buckley M; Ross JP; Zotenko E; Song JZ; Stirzaker C; Bauer DC; Qu W; Swarbrick MM; Lutgers HL; Lord RV; Samaras K; Molloy PL; Clark SJ, 2019, 'Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes', Scientific Reports, vol. 9, pp. 9511, http://dx.doi.org/10.1038/s41598-019-45777-w
    Journal articles | 2019
    Professor Susan Clark
    Skvortsova K; Masle-Farquhar E; Luu PL; Song JZ; Qu W; Zotenko E; Gould CM; Du Q; Peters TJ; Colino-Sanguino Y; Pidsley R; Nair SS; Khoury A; Smith GC; Miosge LA; Reed JH; Kench JG; Rubin MA; Horvath L; Bogdanovic O; Lim SM; Polo JM; Goodnow CC; Stirzaker C; Clark SJ, 2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, vol. 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
    Journal articles | 2019
    Professor Susan Clark
    Du Q; Bert SA; Armstrong NJ; Caldon CE; Song JZ; Nair SS; Gould CM; Luu PL; Peters T; Khoury A; Qu W; Zotenko E; Stirzaker C; Clark SJ, 2019, 'Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer', Nature Communications, vol. 10, pp. 416, http://dx.doi.org/10.1038/s41467-019-08302-1
    Journal articles | 2019
    Professor Susan Clark
    Giles KA; Gould CM; Du Q; Skvortsova K; Song JZ; Maddugoda MP; Achinger-Kawecka J; Stirzaker C; Clark SJ; Taberlay PC, 2019, 'Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups', Epigenetics and Chromatin, vol. 12, pp. 12, http://dx.doi.org/10.1186/s13072-019-0258-9
    Journal articles | 2019
    Professor Susan Clark
    Colino-Sanguino Y; Cornett EM; Moulder D; Smith GC; Hrit J; Cordeiro-Spinetti E; Vaughan RM; Krajewski K; Rothbart SB; Clark SJ; Valdés-Mora F, 2019, 'A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation', iScience, vol. 21, pp. 773 - 788, http://dx.doi.org/10.1016/j.isci.2019.10.053
    Journal articles | 2019
    Professor Susan Clark
    Milevskiy MJG; Gujral U; Del Lama Marques C; Stone A; Northwood K; Burke LJ; Gee JMW; Nephew K; Clark S; Brown MA, 2019, 'MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer', British Journal of Cancer, vol. 120, pp. 621 - 632, http://dx.doi.org/10.1038/s41416-019-0395-8
    Journal articles | 2019
    Professor Susan Clark
    Mahon KL; Qu W; Lin HM; Spielman C; Cain D; Jacobs C; Stockler MR; Higano CS; de Bono JS; Chi KN; Clark SJ; Horvath LG, 2019, 'Serum Free Methylated Glutathione S-transferase 1 DNA Levels, Survival, and Response to Docetaxel in Metastatic, Castration-resistant Prostate Cancer: Post Hoc Analyses of Data from a Phase 3 Trial', European Urology, vol. 76, pp. 306 - 312, http://dx.doi.org/10.1016/j.eururo.2018.11.001
    Journal articles | 2018
    Professor Susan Clark
    Holliday H; Baker LA; Junankar SR; Clark SJ; Swarbrick A, 2018, 'Epigenomics of mammary gland development', Breast Cancer Research, vol. 20, http://dx.doi.org/10.1186/s13058-018-1031-x
    Journal articles | 2018
    Professor Susan Clark
    Stirzaker C; Song JZ; Statham AL; Clark SJ, 2018, 'Bisulphite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq)', Methods in Molecular Biology, vol. 1708, pp. 285 - 302, http://dx.doi.org/10.1007/978-1-4939-7481-8_15
    Journal articles | 2018
    Professor Susan Clark
    Nair SS; Luu PL; Qu W; Maddugoda M; Huschtscha L; Reddel R; Chenevix-Trench G; Toso M; Kench JG; Horvath LG; Hayes VM; Stricker PD; Hughes TP; White DL; Rasko JEJ; Wong JJL; Clark SJ, 2018, 'Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten', Epigenetics and Chromatin, vol. 11, http://dx.doi.org/10.1186/s13072-018-0194-0
    Journal articles | 2018
    Professor Susan Clark
    Pidsley R; Lawrence MG; Zotenko E; Niranjan B; Statham A; Song J; Chabanon RM; Qu W; Wang H; Richards M; Nair SS; Armstrong NJ; Nim HT; Papargiris M; Balanathan P; French H; Peters T; Norden S; Ryan A; Pedersen J; Kench J; Daly RJ; Horvath LG; Stricker P; Frydenberg M; Taylor RA; Stirzaker C; Risbridger GP; Clark SJ, 2018, 'Enduring epigenetic landmarks define the cancer microenvironment', Genome Research, vol. 28, pp. 625 - 638, http://dx.doi.org/10.1101/gr.229070.117
    Journal articles | 2018
    Professor Susan Clark
    Carpenter BL; Zhou W; Madaj Z; DeWitt AK; Ross JP; Grønbæk K; Liang G; Clark SJ; Molloy PL; Jones PA, 2018, 'Mother–child transmission of epigenetic information by tunable polymorphic imprinting', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, pp. E11970 - E11977, http://dx.doi.org/10.1073/pnas.1815005115
    Journal articles | 2018
    Professor Susan Clark
    O'Donoghue SI; Baldi BF; Clark SJ; Darling AE; Hogan JM; Kaur S; Maier-Hein L; McCarthy DJ; Moore WJ; Stenau E; Swedlow JR; Vuong J; Procter JB, 2018, 'Visualization of Biomedical Data', ANNUAL REVIEW OF BIOMEDICAL DATA SCIENCE, VOL 1, vol. 1, pp. 275 - 304, http://dx.doi.org/10.1146/annurev-biodatasci-080917-013424
    Journal articles | 2017
    Professor Susan Clark
    Knaupp AS; Buckberry S; Pflueger J; Lim SM; Ford E; Larcombe MR; Rossello FJ; de Mendoza A; Alaei S; Firas J; Holmes ML; Nair SS; Clark SJ; Nefzger CM; Lister R; Polo JM, 2017, 'Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming', Cell Stem Cell, vol. 21, pp. 834 - 845.e6, http://dx.doi.org/10.1016/j.stem.2017.11.007
    Journal articles | 2017
    Professor Susan Clark
    Skvortsova K; Zotenko E; Luu PL; Gould CM; Nair SS; Clark SJ; Stirzaker C, 2017, 'Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA', Epigenetics and Chromatin, vol. 10, http://dx.doi.org/10.1186/s13072-017-0123-7
    Journal articles | 2017
    Professor Susan Clark
    Stirzaker C; Song JZ; Ng W; Du Q; Armstrong NJ; Locke WJ; Statham AL; French H; Pidsley R; Valdes-Mora F; Zotenko E; Clark SJ, 2017, 'Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer', Oncogene, vol. 36, pp. 1328 - 1338, http://dx.doi.org/10.1038/onc.2016.297
    Journal articles | 2017
    Professor Susan Clark
    Clark SJ; Molloy PL, 2017, 'Smoke-Induced Changes to the Epigenome Provide Fertile Ground for Oncogenic Mutation', Cancer Cell, vol. 32, pp. 278 - 280, http://dx.doi.org/10.1016/j.ccell.2017.08.016
    Journal articles | 2017
    Professor Susan Clark
    Achinger-Kawecka J; Clark SJ, 2017, 'Disruption of the 3D cancer genome blueprint', Epigenomics, vol. 9, pp. 47 - 55, http://dx.doi.org/10.2217/epi-2016-0111
    Journal articles | 2017
    Professor Susan Clark
    Valdés-Mora F; Gould CM; Colino-Sanguino Y; Qu W; Song JZ; Taylor KM; Buske FA; Statham AL; Nair SS; Armstrong NJ; Kench JG; Lee KML; Horvath LG; Qiu M; Ilinykh A; Yeo-Teh NS; Gallego-Ortega D; Stirzaker C; Clark SJ, 2017, 'Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer', Nature Communications, vol. 8, http://dx.doi.org/10.1038/s41467-017-01393-8
    Journal articles | 2017
    Professor Susan Clark
    Mahon KL; Qu W; Lin H-M; Spielman C; Cain D; Jacobs C; Chi KN; De Bono JS; Higano CS; Clark SJ; Horvath L, 2017, 'Post hoc analysis of a phase III study to test the association between circulating methylated glutathione s transferase (mGSTP1) DNA levels and response to docetaxel (DTX) in metastatic castration resistant prostate cancer (mCRPC).', Journal of Clinical Oncology, vol. 35, pp. 5014 - 5014, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.5014
    Journal articles | 2017
    Professor Susan Clark
    Lawrence M; Pidlsey R; Zotenko E; Niranjan B; Nair S; French H; Statham A; Song J; Chabanon R; Papargiris M; Ellem S; Frydenberg M; Pedersen J; Stirzaker C; Taylor R; Clark S; Risbridger G, 2017, 'Hypomethylation of estrogen receptor alpha: a landmark in the epigenome landscape of prostate cancer stroma', CLINICAL ENDOCRINOLOGY, vol. 86, pp. 23 - 23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000393453600061&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2016
    Professor Susan Clark
    Achinger-Kawecka J; Taberlay PC; Clark SJ, 2016, 'Alterations in three-dimensional organization of the cancer genome and epigenome', Cold Spring Harbor Symposia on Quantitative Biology, vol. 81, pp. 41 - 51, http://dx.doi.org/10.1101/sqb.2016.81.031013
    Journal articles | 2016
    Professor Susan Clark
    Mathe A; Wong-Brown M; Locke WJ; Stirzaker C; Braye SG; Forbes JF; Clark SJ; Avery-Kiejda KA; Scott RJ, 2016, 'DNA methylation profile of triple negative breast cancer-specific genes comparing lymph node positive patients to lymph node negative patients', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep33435
    Journal articles | 2016
    Professor Susan Clark
    Walton SJ; Lewis A; Jeffery R; Thompson H; Feakins R; Giannoulatou E; Yau C; Lindsay JO; Clark SK; Silver A, 2016, 'Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours', Oncoscience, vol. 3, pp. 173 - 185, http://dx.doi.org/10.18632/oncoscience.312
    Journal articles | 2016
    Professor Susan Clark
    Lim AM; Wong NC; Pidsley R; Zotenko E; Corry J; Dobrovic A; Clark SJ; Rischin D; Solomon B, 2016, 'Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas', Clinical Epigenetics, vol. 8, http://dx.doi.org/10.1186/s13148-016-0235-0
    Journal articles | 2016
    Professor Susan Clark
    Milevskiy MJG; Al-Ejeh F; Saunus JM; Northwood KS; Bailey PJ; Betts JA; Reed AEMC; Nephew KP; Stone A; Gee JMW; Dowhan DH; Dray E; Shewan AM; French JD; Edwards SL; Clark SJ; Lakhani SR; Brown MA, 2016, 'Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer', Human Molecular Genetics, vol. 25, pp. 3269 - 3283, http://dx.doi.org/10.1093/hmg/ddw177
    Journal articles | 2016
    Professor Susan Clark
    Stirzaker C; Zotenko E; Clark SJ, 2016, 'Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value', Molecular and Cellular Oncology, vol. 3, http://dx.doi.org/10.1080/23723556.2015.1038424
    Journal articles | 2016
    Professor Susan Clark
    Colino-Sanguino Y; Clark SJ; Valdes-Mora F, 2016, 'H2A.Z acetylation and transcription: Ready, steady, go!', Epigenomics, vol. 8, pp. 583 - 586, http://dx.doi.org/10.2217/epi-2016-0016
    Journal articles | 2016
    Professor Susan Clark
    Taberlay PC; Achinger-Kawecka J; Lun ATL; Buske FA; Sabir KS; Gould CM; Zotenko E; Bert SA; Giles KA; Bauer D; Smyth GK; Stirzaker C; O Donoghue SI; Clark SJ, 2016, 'Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations', Genome Research, vol. 26, pp. 719 - 731, http://dx.doi.org/10.1101/gr.201517.115
    Journal articles | 2016
    Professor Susan Clark
    Pidsley R; Zotenko E; Peters TJ; Lawrence MG; Risbridger GP; Molloy P; Van Djik S; Muhlhausler B; Stirzaker C; Clark SJ, 2016, 'Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling', Genome Biology, vol. 17, http://dx.doi.org/10.1186/s13059-016-1066-1
    Journal articles | 2016
    Professor Susan Clark
    Bock C; Halbritter F; Carmona FJ; Tierling S; Datlinger P; Assenov Y; Berdasco M; Bergmann AK; Booher K; Busato F; Campan M; Dahl C; Dahmcke CM; Diep D; Fernández AF; Gerhauser C; Haake A; Heilmann K; Holcomb T; Hussmann D; Ito M; Kläver R; Kreutz M; Kulis M; Lopez V; Nair SS; Paul DS; Plongthongkum N; Qu W; Queirós AC; Reinicke F; Sauter G; Schlomm T; Statham A; Stirzaker C; Strogantsev R; Urdinguio RG; Walter K; Weichenhan D; Weisenberger DJ; Beck S; Clark SJ; Esteller M; Ferguson-Smith AC; Fraga MF; Guldberg P; Hansen LL; Laird PW; Martín-Subero JI; Nygren AOH; Peist R; Plass C; Shames DS; Siebert R; Sun X; Tost J; Walter J; Zhang K, 2016, 'Quantitative comparison of DNA methylation assays for biomarker development and clinical applications', Nature Biotechnology, vol. 34, pp. 726 - 737, http://dx.doi.org/10.1038/nbt.3605
    Journal articles | 2016
    Professor Susan Clark
    Hou L; Heilbronner U; Degenhardt F; Adli M; Akiyama K; Akula N; Ardau R; Arias B; Backlund L; Banzato CEM; Benabarre A; Bengesser S; Bhattacharjee AK; Biernacka JM; Birner A; Brichant-Petitjean C; Bui ET; Cervantes P; Chen GB; Chen HC; Chillotti C; Cichon S; Clark SR; Colom F; Cousins DA; Cruceanu C; Czerski PM; Dantas CR; Dayer A; Étain B; Falkai P; Forstner AJ; Frisén L; Fullerton JM; Gard S; Garnham JS; Goes FS; Grof P; Gruber O; Hashimoto R; Hauser J; Herms S; Hoffmann P; Hofmann A; Jamain S; Jiménez E; Kahn JP; Kassem L; Kittel-Schneider S; Kliwicki S; König B; Kusumi I; Lackner N; Laje G; Landén M; Lavebratt C; Leboyer M; Leckband SG; Jaramillo CAL; Macqueen G; Manchia M; Martinsson L; Mattheisen M; McCarthy MJ; McElroy SL; Mitjans M; Mondimore FM; Monteleone P; Nievergelt CM; Nöthen MM; Ösby U; Ozaki N; Perlis RH; Pfennig A; Reich-Erkelenz D; Rouleau GA; Schofield PR; Schubert KO; Schweizer BW; Seemüller F; Severino G; Shekhtman T; Shilling PD; Shimoda K; Simhandl C; Slaney CM; Smoller JW; Squassina A; Stamm T; Stopkova P; Tighe SK; Tortorella A; Turecki G; Volkert J; Witt S; Wright A; Young LT; Zandi PP; Potash JB; Depaulo JR, 2016, 'Genetic variants associated with response to lithium treatment in bipolar disorder: A genome-wide association study', The Lancet, vol. 387, pp. 1085 - 1093, http://dx.doi.org/10.1016/S0140-6736(16)00143-4
    Journal articles | 2016
    Professor Susan Clark
    Pidsley R; Zotenko E; Peters TJ; Lawrence MG; Risbridger GP; Molloy P; Van Djik S; Muhlhausler B; Stirzaker C; Clark SJ, 2016, 'Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling', GENOME BIOLOGY, vol. 17, http://dx.doi.org/10.1186/s13059-016-1066-1
    Journal articles | 2015
    Professor Susan Clark
    Clark S; Sarlin P; Sharma A; Sisson SA, 2015, 'Increasing dependence on foreign water resources? An assessment of trends in global virtual water flows using a self-organizing time map', Ecological Informatics, vol. 26, pp. 192 - 202, http://dx.doi.org/10.1016/j.ecoinf.2014.05.012
    Journal articles | 2015
    Professor Susan Clark
    Locke WJ; Zotenko E; Stirzaker C; Robinson MD; Hinshelwood RA; Stone A; Reddel RR; Huschtscha LI; Clark SJ, 2015, 'Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis', Clinical Epigenetics, vol. 7, http://dx.doi.org/10.1186/s13148-015-0086-0
    Journal articles | 2015
    Professor Susan Clark
    Van Dijk SJ; Molloy PL; Varinli H; Morrison JL; Muhlhausler BS; Buckley M; Clark SJ; McMillen IC; Noakes M; Samaras K; Tellam RL, 2015, 'Epigenetics and human obesity', International Journal of Obesity, vol. 39, pp. 85 - 97, http://dx.doi.org/10.1038/ijo.2014.34
    Journal articles | 2015
    Professor Susan Clark
    Statham AL; Taberlay PC; Kelly TK; Jones PA; Clark SJ, 2015, 'Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines', Genomics Data, vol. 3, pp. 94 - 96, http://dx.doi.org/10.1016/j.gdata.2014.11.012
    Journal articles | 2015
    Professor Susan Clark
    Varinli H; Statham AL; Clark SJ; Molloy PL; Ross JP, 2015, 'COBRA-seq: Sensitive and quantitative methylome profiling', Genes, vol. 6, pp. 1140 - 1163, http://dx.doi.org/10.3390/genes6041140
    Journal articles | 2015
    Professor Susan Clark
    Du Q; Luu PL; Stirzaker C; Clark SJ, 2015, 'Methyl-CpG-binding domain proteins: Readers of the epigenome', Epigenomics, vol. 7, pp. 1051 - 1073, http://dx.doi.org/10.2217/epi.15.39
    Journal articles | 2015
    Professor Susan Clark
    Phua YW; Nguyen A; Roden DL; Elsworth B; Deng N; Nikolic I; Yang J; Mcfarland A; Russell R; Kaplan W; Cowley MJ; Nair R; Zotenko E; O'Toole S; Tan SX; James DE; Clark SJ; Kouros-Mehr H; Swarbrick A, 2015, 'MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene', Breast Cancer Research, vol. 17, http://dx.doi.org/10.1186/s13058-015-0593-0
    Journal articles | 2015
    Professor Susan Clark
    Korbie D; Lin E; Wall D; Nair SS; Stirzaker C; Clark SJ; Trau M, 2015, 'Multiplex bisulfite PCR resequencing of clinical FFPE DNA', Clinical Epigenetics, vol. 7, http://dx.doi.org/10.1186/s13148-015-0067-3
    Journal articles | 2015
    Professor Susan Clark
    Valdés-Mora F; Clark SJ, 2015, 'Prostate cancer epigenetic biomarkers: next-generation technologies', Oncogene, vol. 34, pp. 1609 - 1618, http://dx.doi.org/10.1038/onc.2014.111
    Journal articles | 2015
    Professor Susan Clark
    Peters TJ; Buckley MJ; Statham AL; Pidsley R; Samaras K; V Lord R; Clark SJ; Molloy PL, 2015, 'De novo identification of differentially methylated regions in the human genome', Epigenetics and Chromatin, vol. 8, http://dx.doi.org/10.1186/1756-8935-8-6
    Journal articles | 2015
    Professor Susan Clark
    Stirzaker C; Zotenko E; Song JZ; Qu W; Nair SS; Locke WJ; Stone A; Armstong NJ; Robinson MD; Dobrovic A; Avery-Kiejda KA; Peters KM; French JD; Stein S; Korbie DJ; Trau M; Forbes JF; Scott RJ; Brown MA; Francis GD; Clark SJ, 2015, 'Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value', Nature Communications, vol. 6, pp. 5899 - 5899, http://dx.doi.org/10.1038/ncomms6899
    Journal articles | 2015
    Professor Susan Clark
    Stone A; Zotenko E; Locke WJ; Korbie D; Millar EKA; Pidsley R; Stirzaker C; Graham P; Trau M; Musgrove EA; Nicholson RI; Gee JMW; Clark SJ, 2015, 'DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer', Nature Communications, vol. 6, http://dx.doi.org/10.1038/ncomms8758
    Journal articles | 2015
    Professor Susan Clark
    Gallego-Ortega D; Ledger A; Roden DL; Law AMK; Magenau A; Kikhtyak Z; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Herrmann D; Salomon R; Young AIJ; Lee BY; Sergio CM; Kaplan W; Piggin C; Conway JRW; Rabinovich B; Millar EKA; Oakes SR; Chtanova T; Swarbrick A; Naylor MJ; O’Toole S; Green AR; Timpson P; Gee JMW; Ellis IO; Clark SJ; Ormandy CJ, 2015, 'ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells', PLoS Biology, vol. 13, http://dx.doi.org/10.1371/journal.pbio.1002330
    Journal articles | 2015
    Professor Susan Clark
    Lawrence M; Pidsley R; Ellem S; Furic L; Nair S; French H; Stratham A; Larsson O; Frydenberg M; Pedersen J; Buchanan G; Taylor R; Clark S; Risbridger G, 2015, 'Oestrogen receptor α promotes prostate cancer progression through dual actions in both epithelia and stroma', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.37.oc8.5
    Journal articles | 2014
    Professor Susan Clark
    Clark S; Sisson SA; Sharma A, 2014, 'A dimension range representation (DRR) measure for self-organizing maps', Pattern Recognition, http://dx.doi.org/10.1016/j.patcog.2015.11.002
    Journal articles | 2014
    Professor Susan Clark
    Skulte KA; Phan L; Clark SJ; Taberlay PC, 2014, 'Chromatin remodeler mutations in human cancers: Epigenetic implications', Epigenomics, vol. 6, pp. 397 - 414, http://dx.doi.org/10.2217/epi.14.37
    Journal articles | 2014
    Professor Susan Clark
    Ali NA; Wu J; Hochgräfe F; Chan H; Nair R; Ye S; Zhang L; Lyons RJ; Pinese M; Lee HC; Armstrong N; Ormandy CJ; Clark SJ; Swarbrick A; Daly RJ, 2014, 'Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways', Breast Cancer Research, vol. 16, http://dx.doi.org/10.1186/s13058-014-0437-3
    Journal articles | 2014
    Professor Susan Clark
    Mahon KL; Qu W; Devaney J; Paul C; Castillo L; Wykes RJ; Chatfield MD; Boyer MJ; Stockler MR; Marx G; Gurney H; Mallesara G; Molloy PL; Horvath LG; Clark SJ, 2014, 'Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer', British Journal of Cancer, vol. 111, pp. 1802 - 1809, http://dx.doi.org/10.1038/bjc.2014.463
    Journal articles | 2014
    Professor Susan Clark
    Stirzaker C; Taberlay PC; Statham AL; Clark SJ, 2014, 'Mining cancer methylomes: Prospects and challenges', Trends in Genetics, vol. 30, pp. 75 - 84, http://dx.doi.org/10.1016/j.tig.2013.11.004
    Journal articles | 2014
    Professor Susan Clark
    Taberlay PC; Statham AL; Kelly TK; Clark SJ; Jones PA, 2014, 'Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer', Genome Research, vol. 24, pp. 1421 - 1432, http://dx.doi.org/10.1101/gr.163485.113
    Journal articles | 2014
    Professor Susan Clark
    Warton K; Lin V; Navin T; Armstrong NJ; Kaplan W; Ying K; Gloss B; Mangs H; Nair SS; Hacker NF; Sutherland RL; Clark SJ; Samimi G, 2014, 'Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma', BMC Genomics, vol. 15, http://dx.doi.org/10.1186/1471-2164-15-476
    Journal articles | 2014
    Professor Susan Clark
    Lin HM; Castillo L; Mahon KL; Chiam K; Lee BY; Nguyen Q; Boyer MJ; Stockler MR; Pavlakis N; Marx G; Mallesara G; Gurney H; Clark SJ; Swarbrick A; Daly RJ; Horvath LG, 2014, 'Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer', British Journal of Cancer, vol. 110, pp. 2462 - 2471, http://dx.doi.org/10.1038/bjc.2014.181
    Journal articles | 2014
    Professor Susan Clark
    Buske FA; French HJ; Smith MA; Clark SJ; Bauer DC, 2014, 'NGSANE: a lightweight production informatics framework for high-throughput data analysis', Bioinformatics, vol. 30, pp. 1471 - 1472, http://dx.doi.org/10.1093/bioinformatics/btu036
    Journal articles | 2014
    Professor Susan Clark
    Riebler A; Menigatti M; Song JZ; Statham AL; Stirzaker C; Mahmud N; Mein CA; Clark SJ; Robinson MD, 2014, 'BayMeth:Improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach', Genome Biology, vol. 15, http://dx.doi.org/10.1186/gb-2014-15-2-r35
    Journal articles | 2014
    Professor Susan Clark
    Gloss B; Moran-Jones K; Lin V; Gonzalez M; Scurry J; Hacker NF; Sutherland RL; Clark SJ; Samimi G, 2014, 'ZNF300P1 Encodes a lincRNA that regulates cell polarity and is epigenetically silenced in type II epithelial ovarian cancer', Molecular Cancer, vol. 13, http://dx.doi.org/10.1186/1476-4598-13-3
    Journal articles | 2013
    Professor Susan Clark
    Hulf T; Sibbritt T; Wiklund ED; Patterson K; Song JZ; Stirzaker C; Qu W; Nair S; Horvath LG; Armstrong NJ; Kench JG; Sutherland RL; Clark SJ, 2013, 'Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer', Oncogene, vol. 32, pp. 2891 - 2899, http://dx.doi.org/10.1038/onc.2012.300
    Journal articles | 2013
    Professor Susan Clark
    Stone A; Valdes-Mora F; Clark SJ, 2013, 'Exploring and exploiting the aberrant DNA methylation profile of endocrine-resistant breast cancer', Epigenomics, vol. 5, pp. 595 - 598, http://dx.doi.org/10.2217/epi.13.70
    Journal articles | 2013
    Professor Susan Clark
    Clark AK; Taubenberger AV; Taylor RA; Niranjan B; Chea ZY; Zotenko E; Sieh S; Pedersen JS; Norden S; Frydenberg M; Grummet JP; Pook DW; Stirzaker C; Clark SJ; Lawrence MG; Ellem SJ; Hutmacher DW; Risbridger GP, 2013, 'A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer', Biomaterials, vol. 34, pp. 4777 - 4785, http://dx.doi.org/10.1016/j.biomaterials.2013.03.005
    Journal articles | 2013
    Professor Susan Clark
    Bert SA; Robinson MD; Strbenac D; Statham AL; Song JZ; Hulf T; Sutherland RL; Coolen MW; Stirzaker C; Clark SJ, 2013, 'Regional Activation of the Cancer Genome by Long-Range Epigenetic Remodeling', Cancer Cell, vol. 23, pp. 9 - 22, http://dx.doi.org/10.1016/j.ccr.2012.11.006
    Journal articles | 2013
    Professor Susan Clark
    Stone A; Cowley MJ; Valdes-Mora F; McCloy RA; Sergio CM; Gallego-Ortega D; Caldon CE; Ormandy CJ; Biankin AV; Gee JMW; Nicholson RI; Print CG; Clark SJ; Musgrove EA, 2013, 'BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer', Molecular Cancer Therapeutics, vol. 12, pp. 1874 - 1885, http://dx.doi.org/10.1158/1535-7163.MCT-13-0012
    Journal articles | 2013
    Professor Susan Clark
    Warton K; Vita L; Armstrong NJ; Kaplan W; Ying K; Mangs H; Hacker NF; Sutherland RL; Clark SJ; Samimi G, 2013, 'Whole genome sequencing of free circulating DNA from plasma of HGSOC patients', CLINICAL CANCER RESEARCH, vol. 19, http://dx.doi.org/10.1158/1078-0432.OVCA13-A4
    Journal articles | 2012
    Professor Susan Clark
    Wee EJH; Peters K; Nair SS; Hulf T; Stein S; Wagner S; Bailey PJ; Lee SY; Qu WJ; Brewster B; French JD; Dobrovic A; Francis GD; Clark SJ; Brown MA, 2012, 'Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer', Oncogene, vol. 31, pp. 4182 - 4195, http://dx.doi.org/10.1038/onc.2011.584
    Journal articles | 2012
    Professor Susan Clark
    Valdes-Mora F; Song JZ; Statham AL; Strbenac D; Robinson MD; Nair SS; Patterson K; Tremethick DJ; Stirzaker C; Clark SJ, 2012, 'Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer', Genome Research, vol. 22, pp. 307 - 321, http://dx.doi.org/10.1101/gr.118919.110
    Journal articles | 2012
    Professor Susan Clark
    Beck S; Bernstein BE; Campbell RM; Costello JF; Dhanak D; Ecker JR; Greally JM; Issa JP; Laird PW; Polyak K; Tycko B; Jones PA; Force ACET, 2012, 'A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force', Cancer Res, vol. 72, pp. 6319 - 6324, http://dx.doi.org/10.1158/0008-5472.CAN-12-3658
    Journal articles | 2012
    Professor Susan Clark
    Robinson MD; Strbenac D; Stirzaker C; Statham A; Song JZ; Speed TP; Clark SJ, 2012, 'Copy-number-aware differential analysis of quantitative DNA sequencing data', Genome Research, vol. 22, pp. 2490 - 2496, http://dx.doi.org/10.1101/gr.139055.112
    Journal articles | 2012
    Professor Susan Clark
    Peters K; Edwards S; Nair SS; French J; Bailey PJ; Salkield K; Stein SR; Wagner S; Francis G; Clark SJ; Brown M, 2012, 'Androgen receptor expression predicts breast cancer survival: The role of genetic and epigenetic events', BMC Cancer, vol. 12, pp. 132, http://dx.doi.org/10.1186/1471-2407-12-132
    Journal articles | 2012
    Professor Susan Clark
    Gloss B; Patterson K; Barton CA; Gonzalez M; Scurry JP; Hacker NF; Sutherland RL; O''brien P; Clark SJ, 2012, 'Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers', Cancer Letters, vol. 318, pp. 76 - 85, http://dx.doi.org/10.1016/j.canlet.2011.12.003
    Journal articles | 2012
    Professor Susan Clark
    Kalyuga M; Gallego-Ortega D; Lee H; Roden DL; Cowley MJ; Caldon CE; Stone A; Allerdice SL; Valdes-Mora F; Rosalind launchbury R; Statham A; Armstrong NJ; Alles MC; Adelaide young A; Egger A; Au W; Piggin CL; Evans C; Ledger A; Brummer T; Oakes SR; Kaplan W; Gee JMW; Robert i nicholson RI; Sutherland RL; Swarbrick A; Naylor MJ; Clark SJ; Carroll JS; Ormandy CJ, 2012, 'ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer', PLoS Biology, vol. 10, pp. e1001461, http://dx.doi.org/10.1371/journal.pbio.1001461
    Journal articles | 2011
    Professor Susan Clark
    Devaney J; Stirzaker C; Qu W; Song JZ; Statham AL; Patterson K; Horvath LG; Tabor B; Coolen MW; Hulf T; Kench JG; Henshall SM; Pe benito R; Haynes AM; Mayor R; Peinado M; Sutherland RL; Clark SJ, 2011, 'Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers', Cancer Epidemiology Biomarkers and Prevention, vol. 20, pp. 148 - 159, http://dx.doi.org/10.1158/1055-9965.EPI-10-0719
    Journal articles | 2011
    Professor Susan Clark
    Hulf T; Sibbritt T; Wikland K; Bert S; Strbenac D; Statham AL; Robinson M; Clark SJ, 2011, 'Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription', BMC Genomics, vol. 12, pp. 54 - 64, http://dx.doi.org/10.1186/1471-2164-12-54
    Journal articles | 2011
    Professor Susan Clark
    Wikland E; Gao SJ; Hulf T; Sibbritt T; Nair SS; Costea A; Villadsen S; Bakholdt V; Bramsen J; Sorensen J; Krogdahl A; Clark SJ; Kjems J, 2011, 'MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma', PLoS One, vol. 6, pp. e27840 - e27851, http://dx.doi.org/10.1371/journal.pone.0027840
    Journal articles | 2011
    Professor Susan Clark
    Coolen MW; Statham A; Qu W; Campbell M; Henders AK; Montgomery GW; Martin N; Clark SJ, 2011, 'Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins', PLoS One, vol. 6, pp. e25590, http://dx.doi.org/10.1371/journal.pone.0025590
    Journal articles | 2011
    Professor Susan Clark
    Braithwaite J; Westbrook J; Johnston BW; Clarke S; Brandon M; Banks M; Hughes C; Greenfield DR; Pawsey M; Corbett AD; Georgiou A; Callen J; Ovreveit J; Pope C; Suñol R; Shaw C; Debono DS; Westbrook MT; Hinchcliff R; Moldovan M, 2011, 'Strengthening organizational performance through accreditation research - a framework for twelve interrelated studies: the ACCREDIT project study protocol', BMC Research Notes, vol. 4, pp. 390 - 399, http://dx.doi.org/10.1186/1756-0500-4-390
    Journal articles | 2011
    Professor Susan Clark
    Hansen TK; Wiklund ED; Bramsen J; Villadsen S; Statham AL; Clark SJ; Kjems J, 2011, 'miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA', European Molecular Biology Organization, vol. 30, pp. 4414 - 4422, http://dx.doi.org/10.1038/emboj.2011.359
    Journal articles | 2011
    Professor Susan Clark
    Jeronimo C; Bastian PJ; Bjartell A; Carbone GM; Catto JWF; Clark SJ; Henrique R; Nelson WG; Shariat SF, 2011, 'Epigenetics in prostate cancer: Biologic and clinical relevance', European Urology, vol. 60, pp. 753 - 766, http://dx.doi.org/10.1016/j.eururo.2011.06.035
    Journal articles | 2011
    Professor Susan Clark
    Wikland E; Bramsen J; Hulf T; Dyrskjot L; Ramanathan P; Hansen TK; Villadsen S; Gao SJ; Ostenfeld MS; Borre M; Peters M; Ortntoft T; Kjems J; Clark SJ, 2011, 'Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer', International Journal of Cancer, vol. 128, pp. 1327 - 1334, http://dx.doi.org/10.1002/ijc.25461
    Journal articles | 2011
    Professor Susan Clark
    Nair SS; Coolen MW; Stirzaker C; Song J; Statham AL; Strbenac D; Robinson MR; Clark SJ, 2011, 'Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias', Epigenetics, vol. 6, pp. 34 - 44, http://dx.doi.org/10.4161/epi.6.1.13313
    Journal articles | 2011
    Professor Susan Clark
    Lee HJ; Hinshelwood R; Bouras T; Gallego-Ortega D; Valdes-Mora F; Blazek K; Visvader JE; Clark SJ; Ormandy CJ, 2011, 'Lineage specific methylation of the Elf5 promoter in mammary epithelial cells', Stem Cells, vol. 29, pp. 1611 - 1619, http://dx.doi.org/10.1002/stem.706
    Journal articles | 2011
    Professor Susan Clark
    Robinson MD; Stirzaker C; Statham AL; Coolen MW; Song JZ; Nair SS; Strbenac D; Speed TP; Clark SJ, 2011, 'Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation (Genome Research (2010), 20 (1719-1729))', Genome Research, vol. 21, pp. 146
    Journal articles | 2011
    Professor Susan Clark
    Patterson K; Molloy L; Qu W; Clark S, 2011, 'DNA methylation: Bisulphite modification and analysis', Journal of Visualized Experiments, http://dx.doi.org/10.3791/3170
    Journal articles | 2011
    Professor Susan Clark
    Mayor R; Munoz M; Coolen MW; Custodio J; Esteller M; Clark SJ; Peinado M, 2011, 'Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells', Epigenetics, vol. 6, pp. 1138 - 1148, http://dx.doi.org/10.4161/epi.6.9.16066
    Journal articles | 2011
    Professor Susan Clark
    Patterson K; Molloy L; Qu W; Clark S, 2011, 'DNA methylation: bisulphite modification and analysis.', Journal of visualized experiments : JoVE
    Journal articles | 2011
    Professor Susan Clark
    Horvath L; Mahon KL; Qu W; Devaney J; Chatfield MD; Paul C; Wykes R; Boyer MJ; Stockler MR; Marx GM; Sutherland RL; Clark SJ, 2011, 'A study of methylated glutathione s-transferase 1 (mGSTP1)as a potential plasma epigenetic marker of response to chemotherapy and prognosis in men with castration-resistant prostate cancer (CRPC).', J Clin Oncol, vol. 29, pp. 4603, http://www.ncbi.nlm.nih.gov/pubmed/28024014
    Journal articles | 2010
    Professor Susan Clark
    Wiklund ED; Kjems J; Clark SJ, 2010, 'Epigenetic architecture and miRNA: Reciprocal regulators', Epigenomics, vol. 2, pp. 823 - 840, http://dx.doi.org/10.2217/epi.10.51
    Journal articles | 2010
    Professor Susan Clark
    Statham AL; Strbenac D; Coolen M; Stirzaker C; Robinson M; Clark SJ, 2010, 'Repitools: an R package for the analysis of enrichment-based epigenomic data', Bioinformatics, vol. 26, pp. 1662 - 1663, http://dx.doi.org/10.1093/bioinformatics/btq247
    Journal articles | 2010
    Professor Susan Clark
    Coolen M; Stirzaker C; Song JZ; Statham AL; Kassir Z; Moreno CS; Young AM; Varma V; Speed TP; Cowley MJ; Lacaze P; Kaplan W; Robinson M; Clark SJ, 2010, 'Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity', Nature Cell Biology, vol. 12, pp. 235 - 246, http://dx.doi.org/10.1038/ncb2023
    Journal articles | 2010
    Professor Susan Clark
    Barton CA; Gloss B; Qu W; Statham AL; Hacker NF; Sutherland RL; Clark SJ; O Brien P, 2010, 'Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival', British Journal of Cancer, vol. 102, pp. 87 - 96, http://dx.doi.org/10.1038/sj.bjc.6605429
    Journal articles | 2010
    Professor Susan Clark
    Robinson M; Stirzaker C; Statham AL; Coolen M; Song J; Nair S; Strbenac D; Speed TP; Clark SJ, 2010, 'Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation', Genome Research, vol. 20, pp. 1719 - 1729, http://dx.doi.org/10.1101/gr.110601.110
    Journal articles | 2010
    Professor Susan Clark
    Robinson M; Statham AL; Speed TP; Clark SJ, 2010, 'Protocol matters: Which methylome are you actually studying?', Epigenomics, vol. 2, pp. 587 - 598, http://dx.doi.org/10.2217/epi.10.36
    Journal articles | 2010
    Professor Susan Clark
    Kjems J; Wiklund ED; Bramsen JB; Hulf T; Dyrskjot L; Clark SJ, 2010, 'Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer', NEW BIOTECHNOLOGY, vol. 27, pp. S7 - S8, http://dx.doi.org/10.1016/j.nbt.2010.01.303
    Journal articles | 2009
    Professor Susan Clark
    Hinshelwood R; Melki J; Huschtscha L; Paul C; Song JZ; Stirzaker C; Reddel RR; Clark SJ, 2009, 'Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning', Human Molecular Genetics, vol. 18, pp. 3098 - 3109, http://dx.doi.org/10.1093/hmg/ddp251
    Journal articles | 2009
    Professor Susan Clark
    Mayor R; Casadome L; Azuara D; Moreno V; Clark SJ; Capella G; Peinado M, 2009, 'Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease', British Journal of Cancer, vol. 100, pp. 1534 - 1539, http://dx.doi.org/10.1038/sj.bjc.6605045
    Journal articles | 2009
    Professor Susan Clark
    McCormack A; McDonald K; Gill A; Clark SJ; Burt MG; Campbell K; Braund W; Little N; Cook R; Grossman AB; Robinson BG; Clifton-Bligh R, 2009, 'Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours', Clinical Endocrinology, vol. 71, pp. 226 - 233, http://dx.doi.org/10.1111/j.1365-2265.2008.03487.x
    Journal articles | 2009
    Professor Susan Clark
    Hynd PI; Edwards NM; Hebart M; McDowall M; Clark S, 2009, 'Wool fibre crimp is determined by mitotic asymmetry and position of final keratinisation and not ortho- and para-cortical cell segmentation', Animal, vol. 3, pp. 838 - 843, http://dx.doi.org/10.1017/S1751731109003966
    Journal articles | 2008
    Professor Susan Clark
    Hinshelwood R; Clark SJ, 2008, 'Breast cancer epigenetics: normal human mammary epithelial cells as a model system', Journal of Molecular Medicine - Jmm, vol. 86, pp. 1315 - 1328, http://dx.doi.org/10.1007/s00109-008-0386-3
    Journal articles | 2008
    Professor Susan Clark
    Guerrero-Bosagna CM; Sabat P; Valdovinos FS; Valladares LE; Clark SJ, 2008, 'Epigenetic and phenotypic changes result from a continuous pre and post dietary exposure to phytoestrogens in an experimental population of mice', BMC Physiology, vol. 8, pp. 1 - 19, http://dx.doi.org/10.1186/1472-6793-8-17
    Journal articles | 2008
    Professor Susan Clark
    Barton CA; Hacker NF; Clark SJ; O Brien P, 2008, 'DNA methylation changes in ovarian cancer: Implications for early diagnosis, prognosis and treatment', Gynecologic Oncology, vol. 109, pp. 129 - 139, http://dx.doi.org/10.1016/j.ygyno.2007.12.017
    Journal articles | 2008
    Professor Susan Clark
    jones PD; Archer T; Baylin S; Beck S; Berger SM; Bernstein B; Carpten J; Clark SJ; Costello J; Doerge R; Esteller M; Feinberg A; Gingeras T; Greally J; Henikoff S; Herman J; Jackson-Grusby L; Jenuwein T; Jirtle R; Lim B; Laird P; Lim B; Martienssen R; Polyak K; Stunnenberg H; Tlsty T; Tycko B; Ushijima T; Zhu J; Pirrotta V; Allis C; Elgin S; Rine J; Wu C, 2008, 'Moving AHEAD with an international human epigenome project', Nature, vol. 454, pp. 711 - 715, http://dx.doi.org/10.1038/454711a
    Journal articles | 2008
    Professor Susan Clark
    Barton CA; Clark SJ; Hacker NF; O Brien P, 2008, 'Epigenetic markers of ovarian cancer', Advances in Experimental Medicine and Biology, vol. 622, pp. 35 - 51, http://dx.doi.org/10.1007/978-0-387-68969-2_4
    Journal articles | 2007
    Professor Susan Clark
    Hinshelwood R; Huschtscha L; Melki J; Stirzaker C; Abdipranoto A; Vissel B; Ravasi T; Wells C; Hume DP; Reddel R; Clark SJ, 2007, 'Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis', Cancer research, vol. 67, pp. 11517 - 11527, http://dx.doi.org/10.1158/0008-5472.CAN-07-1284
    Journal articles | 2007
    Professor Susan Clark
    Coolen M; Statham A; Gardiner-Garden M; Clark SJ, 2007, 'Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements', Nucleic Acids Research, vol. 35, http://dx.doi.org/10.1093/nar/gkm662
    Journal articles | 2007
    Professor Susan Clark
    Clark SJ, 2007, 'Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis', Human Molecular Genetics, vol. 16, pp. R88 - R95, http://dx.doi.org/10.1093/hmg/ddm051
    Journal articles | 2007
    Professor Susan Clark
    Hitchins MP; Ap Lin V; Buckle AD; Cheong KF; Halani N; Ku S; Kwok C; Packham D; Suter CM; Meagher AP; Stirzaker C; Clark SJ; Hawkins NJ; Ward RL, 2007, 'Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer', Cancer research, vol. 67, pp. 9107 - 9116, http://dx.doi.org/10.1158/0008-5472.CAN-07-0869
    Journal articles | 2006
    Professor Susan Clark
    Frigola J; Song J; Stirzaker C; Hinshelwood R; Peinado M; Clark SJ, 2006, 'Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band', Nature Genetics, vol. 38, pp. 540 - 549, http://dx.doi.org/10.1038/ng1781
    Journal articles | 2006
    Professor Susan Clark
    Wen VW; Wu K; Baksh S; Hinselwood RA; Lock RB; Clark SJ; Moore MA; Mackenzie K, 2006, 'Telomere-driven karyotypic complexity concurs with p16INK4a inactivation in TP53 competent immortal endothelial cells', Cancer research, vol. 66, pp. 10691 - 10700, http://dx.doi.org/10.1158/0008-5472.CAN-06-0979
    Journal articles | 2006
    Professor Susan Clark
    Wong NC; Wong LH; Quach JM; Canham P; Craig JM; Song JZ; Clark SJ; Choo KHA, 2006, 'Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation', PLoS Genetics, vol. 2, pp. 172 - 186, http://dx.doi.org/10.1179/146531205225021589
    Journal articles | 2006
    Professor Susan Clark
    Clark SJ; Statham A; Stirzaker C; Molloy PL; Frommer M, 2006, 'DNA methylation: Bisulphite modification and analysis', Nature Protocols, vol. 1, pp. 2353 - 2364, http://dx.doi.org/10.1038/nprot.2006.324
    Journal articles | 2006
    Professor Susan Clark
    Rand KN; Mitchell SM; Clark SJ; Molloy PL, 2006, 'Bisulphite differential denaturation PCR for analysis of DNA methylation', Epigenetics, vol. 1, pp. 94 - 100, http://dx.doi.org/10.4161/epi.1.2.2680
    Journal articles | 2005
    Professor Susan Clark
    Frigola J; Munoz MA; Clark SJ; Moreno V; Capella G; Peinado M, 2005, 'Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy', Oncogene, vol. 24, pp. 7320 - 7326, http://dx.doi.org/10.1038/sj.onc.1208883
    Journal articles | 2005
    Professor Susan Clark
    Rand KN; Ho T; Qu W; Mitchell SM; White R; Clark SJ; Molloy PL, 2005, 'Headloop suppression PCR and its application to selective amplification of methylated DNA sequences', Nucleic Acids Research, vol. 33, pp. 1 - 11, http://dx.doi.org/10.1093/nar/gni120
    Journal articles | 2005
    Professor Susan Clark
    Sidhu S; Martin E; Gicquel C; Melki J; Clark SJ; Campbell P; Magarey CJ; Schulte KM; Roher HD; Delbridge L; Robinson BG, 2005, 'Mutation and methylation analysis of TP53 in adrenal carcinogenesis', Eur J Surg Oncol, vol. 31, pp. 549 - 554, http://dx.doi.org/10.1016/j.ejso.2005.01.013
    Journal articles | 2005
    Professor Susan Clark
    Rand KN; Ho T; Qu W; Mitchell SM; White R; Clark SJ; Molloy PL, 2005, 'Headloop suppression PCR and its application to selective amplification of methylated DNA sequences.', Nucleic acids research, vol. 33
    Journal articles | 2005
    Professor Susan Clark
    Wong NC-L; Wong LH; Quach JM; Canham P; Craig JM; Song JZ; Clark SJ; Choo A, 2005, 'Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation', PLoS Genetics, vol. preprint, pp. e17 - e17, http://dx.doi.org/10.1371/journal.pgen.0020017.eor
    Journal articles | 2005
    Professor Susan Clark
    Broad A; Links MR; Rosenthal M; Abraham R; Clark SJ; Burns I; Dilulio J; Mitchell P, 2005, 'Oxaliplatin and gemcitabine in advanced NSCLC: A multicentre phase 2 Australian study', Lung Cancer, vol. 49, pp. S239 - S239
    Journal articles | 2004
    Professor Susan Clark
    Noble JR; Zhong ZH; Neumann AA; Melki JR; Clark SJ; Reddel RR, 2004, 'Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts', Oncogene, vol. 23, pp. 3116 - 3121, http://dx.doi.org/10.1038/sj.onc.1207440
    Journal articles | 2004
    Professor Susan Clark
    Stirzaker C; Song J; Davidson B; Clark SJ, 2004, 'Transcriptional Gene Silencing Promotes DNA Hypermethylation through a sequential Change in Chromatin Modifications in Cancer Cells', Cancer research, vol. 64, pp. 3871 - 3877, http://dx.doi.org/10.1158/0008-5472.CAN-03-3690
    Journal articles | 2003
    Professor Susan Clark
    Clark SJ; Millar DS; Molloy P, 2003, 'Bisulfite methylation analysis of tumor suppressor genes in prostate cancer from fresh and archival tissue samples', Methods Mol Med, vol. 81, pp. 219 - 240, http://dx.doi.org/10.1385/1-59259-372-0:219
    Journal articles | 2002
    Professor Susan Clark
    Millar DS; Warnecke PM; Melki JR; Clark SJ, 2002, 'Methylation sequencing from limiting DNA: embryonic, fixed, and microdissected cells', Methods, vol. 27, pp. 108 - 113, http://dx.doi.org/10.1016/S1046-2023(02)00061-0
    Journal articles | 2002
    Professor Susan Clark
    Rand K; Qu W; Ho T; Clark SJ; Molloy P, 2002, 'Conversion-specific detection of DNA methylation using real-time polymerase chain reaction (ConLight-MSP) to avoid false positives', Methods, vol. 27, pp. 114 - 120, http://dx.doi.org/10.1016/S1046-2023(02)00062-2
    Journal articles | 2002
    Professor Susan Clark
    Clark SJ; Melki J, 2002, 'DNA methylation and gene silencing in cancer: which is the guilty party?', Oncogene, vol. 21, pp. 5380 - 5387, http://dx.doi.org/10.1038/sj.onc.1205598
    Journal articles | 2002
    Professor Susan Clark
    Warnecke PM; Stirzaker C; Song J; Grunau C; Melki JR; Clark SJ, 2002, 'Identification and resolution of artifacts in bisulfite sequencing', Methods, vol. 27, pp. 101 - 107, http://dx.doi.org/10.1016/S1046-2023(02)00060-9
    Journal articles | 2002
    Professor Susan Clark
    Song JZ; Stirzaker C; Harrison J; Melki JR; Clark SJ, 2002, 'Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells', Oncogene, vol. 21, pp. 1048 - 1061, http://dx.doi.org/10.1038/sj.onc.1205153
    Journal articles | 2002
    Professor Susan Clark
    Schmitt JF; Millar DS; Pedersen JS; Clark SL; Venter DJ; Frydenberg M; Molloy PL; Risbridger GP, 2002, 'Hypermethylation of the inhibin α-subunit gene in prostate carcinoma', Molecular Endocrinology, vol. 16, pp. 213 - 220, http://dx.doi.org/10.1210/me.16.2.213
    Journal articles | 2002
    Professor Susan Clark
    Melki JR; Clark SJ, 2002, 'DNA methylation changes in leukaemia', Semin Cancer Biol, vol. 12, pp. 347 - 357, http://dx.doi.org/10.1016/S1044-579X(02)00055-X
    Journal articles | 2002
    Professor Susan Clark
    Schmitt JF; Millar DS; Pedersen JS; Clark SL; Venter DJ; Frydenberg M; Molloy PL; Risbridger GP, 2002, 'Hypermethylation of the inhibin alpha-subunit gene in prostate carcinoma', Mol Endocrinol, vol. 16, pp. 213 - 220, http://dx.doi.org/10.1210/mend.16.2.0771
    Journal articles | 2002
    Professor Susan Clark
    Clark SJ; Warnecke PM, 2002, 'DNA methylation analysis in mammalian cells', Methods, vol. 27, pp. 99 - 100, http://dx.doi.org/10.1016/S1046-2023(02)00059-2
    Journal articles | 2001
    Professor Susan Clark
    Grunau C; Renault E; Rosenthal A; Roizes G, 2001, 'MethDB - a public database for DNA methylation data', NUCLEIC ACIDS RESEARCH, vol. 29, pp. 270 - 274, http://dx.doi.org/10.1093/nar/29.1.270
    Journal articles | 2001
    Professor Susan Clark
    Grunau C; Clark SJ; Rosenthal A, 2001, 'Bisulfite genomic sequencing: systematic investigation of critical experimental parameters', Nucleic Acids Res, vol. 29, pp. E65 - E65, http://www.ncbi.nlm.nih.gov/pubmed/11433041
    Journal articles | 2001
    Professor Susan Clark
    Chetcuti A; Margan SH; Russell P; Mann S; Millar DS; Clark SJ; Rogers J; Handelsman DJ; Dong Q, 2001, 'Loss of annexin II heavy and light chains in prostate cancer and its precursors', Cancer Res, vol. 61, pp. 6331 - 6334, http://www.ncbi.nlm.nih.gov/pubmed/11522620
    Journal articles | 2001
    Professor Susan Clark
    Welch J; Millar D; Goldman A; Heenan P; Stark M; Eldon M; Clark S; Martin NG; Hayward NK, 2001, 'Lack of genetic and epigenetic changes in CDKN2A in melanocytic nevi', J Invest Dermatol, vol. 117, pp. 383 - 384, http://dx.doi.org/10.1046/j.0022-202x.2001.01391.x
    Journal articles | 2000
    Professor Susan Clark
    Millar DS; Paul CL; Molloy PL; Clark SJ, 2000, 'A distinct sequence (ATAAA)n separates methylated and unmethylated domains at the 5'-end of the GSTP1 CpG island', J Biol Chem, vol. 275, pp. 24893 - 24899, http://dx.doi.org/10.1074/jbc.M906538199
    Journal articles | 2000
    Professor Susan Clark
    Melki JR; Vincent PC; Brown RD; Clark SJ, 2000, 'Hypermethylation of E-cadherin in leukemia', Blood, vol. 95, pp. 3208 - 3213, http://www.ncbi.nlm.nih.gov/pubmed/10807790
    Journal articles | 2000
    Professor Susan Clark
    Jackson P; Millar D; Kingsley E; Yardley G; Ow K; Clark S; Russell PJ, 2000, 'Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines', Cancer Letters, vol. 157, pp. 169 - 176, http://dx.doi.org/10.1016/S0304-3835(00)00483-3
    Journal articles | 2000
    Professor Susan Clark
    Jackson P; Mills DR; Kingsley EA; Yardley G; Ow KT; Clark SJ; Russell PJ, 2000, 'Methylation of a CpG island within the KAI1 promoter region is not responsible for reduced KAI1 expression in invasive bladder cancer or bladder cancer cell lines', Cancer Letters, vol. 157, pp. 169 - 175
    Journal articles | 1999
    Professor Susan Clark
    Warnecke PM; Clark SJ, 1999, 'DNA methylation profile of the mouse skeletal alpha-actin promoter during development and differentiation', Mol Cell Biol, vol. 19, pp. 164 - 172, http://www.ncbi.nlm.nih.gov/pubmed/9858541
    Journal articles | 1999
    Professor Susan Clark
    Melki JR; Vincent PC; Clark SJ, 1999, 'Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia', Cancer Res, vol. 59, pp. 3730 - 3740, http://www.ncbi.nlm.nih.gov/pubmed/10446989
    Journal articles | 1999
    Professor Susan Clark
    Millar DS; Ow KT; Paul CL; Russell PJ; Molloy PL; Clark SJ, 1999, 'Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer', Oncogene, vol. 18, pp. 1313 - 1324, http://dx.doi.org/10.1038/sj.onc.1202415
    Journal articles | 1999
    Professor Susan Clark
    Melki JR; Vincent PC; Clark SJ, 1999, 'Cancer-specific region of hypermethylation identified within the HIC1 putative tumour suppressor gene in acute myeloid leukaemia', Leukemia, vol. 13, pp. 877 - 883, http://dx.doi.org/10.1038/sj.leu.2401401
    Journal articles | 1999
    Professor Susan Clark
    Veitch C; Harte J; Hays R; Pashen D; Clark S, 1999, 'Community participation in the recruitment and retention of rural doctors: methodological and logistical considerations.', The Australian journal of rural health, vol. 7, pp. 206 - 211, http://dx.doi.org/10.1046/j.1440-1584.1999.00213.x
    Journal articles | 1999
    Professor Susan Clark
    Molloy PL; Millar DS; Russell PJ; Clark SJ, 1999, 'Prostate Cancer DNA Methylation assay', Today's Life Science, vol. 11, pp. 34 - 35
    Journal articles | 1998
    Professor Susan Clark
    Melki JR; Warnecke P; Vincent PC; Clark SJ, 1998, 'Increased DNA methyltransferase expression in leukaemia', Leukemia, vol. 12, pp. 311 - 316, http://dx.doi.org/10.1038/sj.leu.2400932
    Journal articles | 1998
    Professor Susan Clark
    Huschtscha LI; Noble JR; Neumann AA; Moy EL; Barry P; Melki JR; Clark SJ; Reddel RR, 1998, 'Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells', Cancer Res, vol. 58, pp. 3508 - 3512, http://www.ncbi.nlm.nih.gov/pubmed/9721850
    Journal articles | 1998
    Professor Susan Clark
    Harrison J; Stirzaker C; Clark SJ, 1998, 'Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts', Anal Biochem, vol. 264, pp. 129 - 132, http://dx.doi.org/10.1006/abio.1998.2833
    Journal articles | 1998
    Professor Susan Clark
    Warnecke PM; Mann JR; Frommer M; Clark SJ, 1998, 'Bisulfite sequencing in preimplantation embryos: DNA methylation profile of the upstream region of the mouse imprinted H19 gene', Genomics, vol. 51, pp. 182 - 190, http://dx.doi.org/10.1006/geno.1998.5371
    Journal articles | 1998
    Professor Susan Clark
    Warnecke PM; Biniszkiewicz D; Jaenisch R; Frommer M; Clark SJ, 1998, 'Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene', Dev Genet, vol. 22, pp. 111 - 121, http://dx.doi.org/10.1002/(SICI)1520-6408(1998)22:2<111::AID-DVG1>3.0.CO;2-9
    Journal articles | 1997
    Professor Susan Clark
    Warnecke PM; Stirzaker C; Melki JR; Millar DS; Paul CL; Clark SJ, 1997, 'Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA', Nucleic Acids Res, vol. 25, pp. 4422 - 4426, http://dx.doi.org/10.1093/nar/25.21.4422
    Journal articles | 1997
    Professor Susan Clark
    Stirzaker C; Millar DS; Paul CL; Warnecke PM; Harrison J; Vincent PC; Frommer M; Clark SJ, 1997, 'Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors', Cancer Research, vol. 57, pp. 2229 - 2237
    Journal articles | 1997
    Professor Susan Clark
    Clark SJ; Harrison J; Molloy PL, 1997, 'Sp1 binding is inhibited by (m)Cp(m)CpG methylation', Gene, vol. 195, pp. 67 - 71, http://dx.doi.org/10.1016/S0378-1119(97)00164-9
    Journal articles | 1997
    Professor Susan Clark
    Melki JR; Vincent PC; Clark SJ, 1997, 'DNA methylation in leukemia', Experimental Hematology, vol. 25, pp. 855
    Journal articles | 1996
    Professor Susan Clark
    Paul CL; Clark SJ, 1996, 'Cytosine methylation: quantitation by automated genomic sequencing and GENESCAN analysis', Biotechniques, vol. 21, pp. 126 - 133, http://www.ncbi.nlm.nih.gov/pubmed/8816247
    Journal articles | 1995
    Professor Susan Clark
    Clark SJ; Harrison J; Frommer M, 1995, 'CpNpG methylation in mammalian cells', Nat Genet, vol. 10, pp. 20 - 27, http://dx.doi.org/10.1038/ng0595-20
    Journal articles | 1994
    Professor Susan Clark
    Clark SJ; Harrison J; Paul CL; Frommer M, 1994, 'High sensitivity mapping of methylated cytosines', Nucleic Acids Res, vol. 22, pp. 2990 - 2997, http://dx.doi.org/10.1093/nar/22.15.2990
    Journal articles | 1994
    Professor Susan Clark
    Harrison J; Molloy PL; Clark SJ, 1994, 'Direct cloning of polymerase chain reaction products in an XcmI T-vector', Anal Biochem, vol. 216, pp. 235 - 236, http://dx.doi.org/10.1006/abio.1994.1033
    Journal articles | 1994
    Professor Susan Clark
    Grigg G; Clark S, 1994, 'Sequencing 5-methylcytosine residues in genomic DNA', Bioessays, vol. 16, pp. 431 - 436, http://dx.doi.org/10.1002/bies.950160612
    Journal articles | 1988
    Professor Susan Clark
    Greenwood PE; Clark SJ; Cahill AD; Trevallyn-Jones J; Tzipori S, 1988, 'Development and protective efficacy of a recombinant-DNA derived fimbrial vaccine against enterotoxic colibacillosis in neonatal piglets', Vaccine, vol. 6, pp. 389 - 392, http://www.ncbi.nlm.nih.gov/pubmed/3057758
    Journal articles | 1982
    Professor Susan Clark
    Rickles R; Marashi F; Sierra F; Clark S; Wells J; Stein J; Stein G, 1982, 'Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes', Proc Natl Acad Sci U S A, vol. 79, pp. 749 - 753, http://dx.doi.org/10.1073/pnas.79.3.749
    Journal articles | 1982
    Professor Susan Clark
    Sierra F; Lichtler A; Marashi F; Rickles R; Van Dyke T; Clark S; Wells J; Stein G; Stein J, 1982, 'Organization of human histone genes', Proc Natl Acad Sci U S A, vol. 79, pp. 1795 - 1799, http://dx.doi.org/10.1073/pnas.79.6.1795
    Journal articles | 1982
    Professor Susan Clark
    Lichtler AC; Sierra F; Clark S; Wells JR; Stein JL; Stein GS, 1982, 'Multiple H4 histone mRNAs of HeLa cells are encoded in different genes', Nature, vol. 298, pp. 195 - 198, http://dx.doi.org/10.1038/298195a0
    Journal articles | 1982
    Professor Susan Clark
    Rickles R; Marashi F; Sierra F; Clark S; Wells J; Stein J; Stein G, 1982, 'Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes', Proceedings of the National Academy of Sciences of the United States of America, vol. 79, pp. 749 - 753, http://dx.doi.org/10.1073/pnas.79.3.749
    Journal articles | 1982
    Professor Susan Clark
    Sierra F; Leza A; Marashi F; Plumb M; Rickles R; Van Dyke T; Clark S; Wells J; Stein GS; Stein JL, 1982, 'Human histone genes are interspersed with members of the Alu family and with other transcribed sequences', Biochem Biophys Res Commun, vol. 104, pp. 785 - 792, http://dx.doi.org/10.1016/0006-291X(82)90706-9
    Journal articles | 1981
    Professor Susan Clark
    Clark SJ; Krieg PA; Wells JR, 1981, 'Isolation of a clone containing human histone genes', Nucleic Acids Res, vol. 9, pp. 1583 - 1590, http://dx.doi.org/10.1093/nar/9.7.1583
    Journal articles |
    Professor Susan Clark
    Giles KA; Gould CM; Achinger-Kawecka J; Page SG; Kafer G; Luu P-L; Cesare AJ; Clark SJ; Taberlay PC, 'BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells', , http://dx.doi.org/10.1101/2020.07.03.187385
  • Conference Abstracts | 2020
    Professor Susan Clark
    Tiedemann R; Du Q; Dickson B; Kong X; Chomiak A; Zhou W; Johnson B; Baylin S; Jones P; Clark S; Rothbart S, 2020, 'High-resolution Epigenome Mapping Reveals Distinct and Divergent Roles for UHRF1 in the Maintenance of DNA Methylation', in FASEB JOURNAL, WILEY, San Diego, CA, Vol. 34, presented at Annual Meeting on Experimental Biology, San Diego, CA, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.05966
    Conference Abstracts | 2019
    Professor Susan Clark
    Stirzaker C; Chia KM; Portman N; Milioli HH; Clifton S; Achinger-Kawecka J; Nair S; Lim E; Clark S, 2019, 'DNA demethylation agents as a therapeutic approach in endocrine-resistant breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P049
    Conference Abstracts | 2018
    Professor Susan Clark
    Mathe A; Wong-Brown M; Morten BC; Braye SG; Locke WJ; Stirzaker C; Clark SJ; Scott R; Avery-Kiejda KA, 2018, 'Defining the Key Mediators of Breast Cancer Progression and Treatment Resistance in the triple Negative Subtype', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 14, pp. 9 - 9, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000446654600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Professor Susan Clark
    Horvath LG; Mahon KL; Qu W; Lin HM; Spielman C; Cain D; Jacobs C; Stockler MR; de Bono JS; Higano CS; Chi KN; Clark SJ, 2018, 'Post Hoc Analysis of a Phase III Study to Test the Association Between Circulating Methylated Glutathione S Transferase (mGSTP1) DNA Levels and Response to Docetaxel (DTX) in Metastatic Castration-Resistant Prostate Cancer (mCRPC)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 14, pp. 51 - 52, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000439493100013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Professor Susan Clark
    Lawrence MG; Pidsley R; Zotenko E; Niranjan B; Statham A; Song J; Armstrong N; Pedersen J; Frydenberg M; Taylor R; Stirzaker C; Risbridger G; Clark S, 2017, 'Abstract 1997: Charting the DNA methylation landscape of prostate cancer associated fibroblasts', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-1997
    Conference Abstracts | 2016
    Professor Susan Clark
    Vuocolo T; Statham A; Bauer DC; McWilliam S; Nair SS; Morrison JL; Zhang S; Buckley M; McMillen IC; Clark SJ; Tellam RL, 2016, 'A hierarchy of epigenetic changes in the developmental transition from brown to white perirenal adipose tissue.', in JOURNAL OF ANIMAL SCIENCE, OXFORD UNIV PRESS INC, Vol. 94, pp. 9 - 10, http://dx.doi.org/10.2527/jas2016.94supplement49a
    Conference Papers | 2016
    Professor Susan Clark
    Milevskiy MJ; Al-Ejeh F; Saunus JM; Northwood KS; McCart-Reed AE; Dray E; Nephew K; Bailey PJ; Betts JA; Stone A; Gee JMW; Shewan AM; French JD; Edwards SL; Clark SJ; Lakhani SR; Brown MA, 2016, 'Abstract 1980: Long-range regulation of HOTAIR identifies novel biomarkers of breast cancer outcome and suggests a role in genome instability', in Molecular and Cellular Biology, Genetics, American Association for Cancer Research, presented at Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA, http://dx.doi.org/10.1158/1538-7445.am2016-1980
    Conference Abstracts | 2016
    Professor Susan Clark
    Mathe A; Wong-Brown M; Locke W; Stirzaker C; Braye S; Forbes J; Clark S; Avery-Kiejda K; Scott R, 2016, 'DNA METHYLATION PROFILE OF TRIPLE NEGATIVE BREAST CANCER-SPECIFIC GENES COMPARING LYMPH NODE POSITIVE PATIENTS TO LYMPH NODE NEGATIVE PATIENTS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 12, pp. 27 - 27, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000387772400056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor Susan Clark
    Lawrence M; Pidsley R; Ellem S; Furic L; Nair S; French H; Statham A; Larsson O; Frydenberg M; Pedersen J; Buchanan G; Taylor R; Clark S; Risbridger G, 2015, 'Surveying the epigenome landscape of the prostate cancer microenvironment: identification of estrogen receptor alpha as a key differentially methylated gene', in CLINICAL ENDOCRINOLOGY, WILEY, Adelaide, AUSTRALIA, Vol. 84, pp. 20 - 20, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 August 2015 - 26 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor Susan Clark
    Gallego-Ortega D; Ledger A; Roden D; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Lee B; Kaplan W; Salomon R; Piggin C; Rabinovich B; Millar E; Chtanova T; Swarbrick A; Clark S; Ormandy C, 2015, 'The ETS transcription factor ELF5 drives metastasis via angiogenesis and recruitment of Gr-1+ CD11b+ myeloid derived suppressor cells in luminal breast cancer', in Clinical and Experimental Metastasis, Springer Verlag (Germany), Vol. 32, pp. 203 - 203, presented at MRS 15th International biennial congress of the metastasis research society, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2014
    Professor Susan Clark
    Clark SJ, 2014, 'EPIGENETIC REMODELING AND REPLICATION TIMING IN CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 28 - 28, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716200018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Professor Susan Clark
    Mahon K; Qu W; Devaney J; Paul C; Castillo L; Chatfield M; Boyer M; Stockler M; Marx G; Gurney H; Mallesara G; Molloy P; Horvath L; Clark S, 2014, 'METHYLATED GLUTATHIONE S-TRANSFERASE 1 (MGSTP1) ASA POTENTIAL PLASMA EPIGENETIC MARKER OF PROGNOSIS AND RESPONSE TO CHEMOTHERAPY IN CASTRATE-RESISTANT PROSTATE CANCER (CRPC)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 27 - 27, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Professor Susan Clark
    Clark S, 2014, 'WHOLE GENOME METHYLATION SEQUENCING IDENTIFIES POTENTIAL EPIGENETIC-BASED CANCER BIOMARKERS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 18 - 19, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Professor Susan Clark
    Mahon KL; Chiam K; Lee BY; Nguyen Q; Boyer MJ; Stockler M; Pavlakis N; Marx G; Mallesara G; Gurney H; Clark S; Swarbrick A; Daly R; Horvath L, 2014, 'CIRCULATING MICRORNAS ASSOCIATED WITH DOCETAXEL-RESISTANT CASTRATION-RESISTANT PROSTATE CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 26 - 27, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716200012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Professor Susan Clark
    Stirzaker C; Song JZ; Statham AL; Robinson M; Lacaze P; Coolen M; Moreno CS; Warren K; Clark SJ, 2009, 'CONSOLIDATION OF THE CANCER EPIGENOME TO REGIONS OF UNIFORM CHROMATIN', in CELLULAR ONCOLOGY, SPRINGER, Edinburgh, SCOTLAND, pp. 101 - 101, presented at 3rd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), Edinburgh, SCOTLAND, 01 April 2009 - 05 April 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265635300028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Professor Susan Clark
    Stirzaker C; Song JZ; Statham AL; Robinson M; Lacaze P; Coolen M; Moreno CS; Warren K; Clark SJ, 2009, 'CONSOLIDATION OF THE CANCER EPIGENOME TO REGIONS OF UNIFORM CHROMATIN', in CELLULAR ONCOLOGY, IOS PRESS, Edinburgh, SCOTLAND, pp. 136 - 136, presented at 3rd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), Edinburgh, SCOTLAND, 01 April 2009 - 05 April 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265635300098&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Professor Susan Clark
    Coolen M; Song J; Statham AL; Lacaze P; Moreno CS; Kaplan W; Stirzaker C; Clark SJ, 2008, 'Long range epigenetic silencing (LRES): A common phenomenon in prostate cancer', in CELLULAR ONCOLOGY, IOS PRESS, Madrid, SPAIN, pp. 225 - 225, presented at 2nd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), Madrid, SPAIN, 04 May 2008 - 07 May 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255341800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2006
    Professor Susan Clark
    Frigola J; Song JZ; Stirzaker C; Peinado MA; Clark SJ, 2006, 'Epigenetic Silent Neighborhoods in Cancer Cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606204232&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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