2005 – 2009 Human Frontier Science Program Postdoctoral Research Fellow –University of California, Berkeley, CA, USA
2001-2005 PhD Scholar – The Garvan Institute of Medical Research/UNSW School of Biotechnology and Biomolecular Sciences, Sydney, Australia
1999 Honours (1st Class) in Biochemistry and Molecular Genetics – UNSW School of Biotechnology and Biomolecular Sciences, Sydney, Australia
1996-1998 B.Sc. Advanced Science – University of New South Wales, Sydney, Australia, Major in Biochemistry and Molecular Genetics
Associate Professor Tatyana Chtanova is the head of the Innate and Tumour Immunology laboratory, School of Biotechnology and Biomolecular Sciences, UNSW Sydney. After undergraduate studies at the University of New South Wales, Tatyana was awarded her PhD in 2005 for her thesis work on specific gene expression signatures for novel T cell subsets, performed at the Garvan Institute.
Following her PhD, Tatyana was awarded the Human Frontier Science Program Fellowship to train at the University of California, Berkeley. During her fellowship she gained expertise in intravital microscopy and applied it to uncover a unique immunological response to inflammation called neutrophil swarming and a novel mechanism of immune evasion by pathogens.
Tatyana’s main research interest is in developing unique approaches such as two-photon microscopy and in situ photoconversion to understand fundamental immunological processes including infection, wound repair and cancer. The overall goal of Tatyana’s research program is to harness inflammation to develop new immunotherapy for cancer and promote wound healing.
NHMRC Career Development Fellowship 1
Human Frontier Science Program Career Development award and Fellowship
Cancer Institute NSW Career Development award
I have led an independent laboratory since 2014 supported by CIA NHMRC and ARC funding. I am a leader in the field of intravital microscopy applied to uncover fundamental principles of immunology, particularly as these relate to innate immunity and cell migration. This is most exemplified by my discovery of neutrophil swarming, a key step in the study of immune cell motility.
An important technological feature of my research is the utilisation of two-photon microscopy to visualise immune responses in vivo. I acquired this technological expertise during my postdoctoral training at UC Berkeley, as Human Frontier Science Program fellow and established this technology at Garvan and continue to champion it. My more recent research brings these cutting-edge approaches to focus on key unmet areas of fundamental biology and health including infection, wound repair and cancer. My field contributions are recognised by peers leading several recent highly-cited senior/corresponding author publications in top tier journals (Immunity, PNAS, Nature Communications and Cancer Research).