Dr Thuy Anh Bui

Dr Thuy Anh Bui

Senior Research Associate

BSc Biomedical Sciences - University of Manchester, UK 

Doctor of Philosophy (PhD) in Physiology - University of Manchester, UK 

Graduate Certificate in Higher Education Teaching and Learning, University of Technology Sydney 

 

 

 

 

Medicine & Health
School of Population Health

I am a Senior Research Fellow who transitioned from a decade of laboratory-based cardiovascular and cancer gene therapy research into clinical research. My PhD work was published in Nature Communications, with additional review articles in Lancet eBiomedicine, Advanced Functional Materials, Bioactive Materials and ACS Nano AU.

I was the project manager for the Hospital in the Home for Hip Fracture project at Liverpool Hospital, which was named as Winner for Health Research Quality Awards in South Western Sydney Local Health District 2025. I now lead the "Rehabilitation in the Home" randomised controlled trial for hip fracture patients at Liverpool and Bankstown-Lidcombe Hospitals, where I coordinate multidisciplinary teams and oversee data analysis.

I also have extensive experience in community engagement, particularly with culturally and linguistically diverse populations in South West Sydney.

  • Journal articles | 2026
    Myooran J; Naylor J; March MK; Chróinín DN; Bui TA; Bednorz N; Chen S-H; Brady B, 2026, 'Understanding Patient and Clinician Perspectives in the HITH4Hips Trial: A Qualitative Study.', Australas J Ageing, 45, pp. e70214, http://dx.doi.org/10.1111/ajag.70214
    Journal articles | 2025
    Lestari B; Nugroho AB; Bui TA; Nguyen B; Stafford N; Prehar S; Zi M; Potter R; Triastuti E; Baudoin FM; D’Souza A; Wang X; Cartwright EJ; Oceandy D, 2025, 'Expression of foetal gene Pontin is essential in protecting heart against pathological remodelling and cardiomyopathy', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-56531-4
    Journal articles | 2025
    Naylor JM; Bùi TA; Frost S; McEvoy L; Harris IA; Lim D; Radhakrishnan S; Johns N; Brady B; Tcharkhedian E; Lieu D; Dickson H; Penm J; Kimmel L; Sidhu B; Ní Chróinín D, 2025, 'Foundations for Developing a Hospital in the Home Pathway Following Low Trauma Hip Fracture: Using Data to Inform the Path', Home Health Care Management and Practice, 37, pp. 242 - 250, http://dx.doi.org/10.1177/10848223241296871
    Journal articles | 2024
    Bui TA; Mei H; Sang R; Ortega DG; Deng W, 2024, 'Advancements and challenges in developing in vivo CAR T cell therapies for cancer treatment', Ebiomedicine, 106, http://dx.doi.org/10.1016/j.ebiom.2024.105266
    Journal articles | 2024
    Mehta M; Bui TA; Care A; Deng W, 2024, 'Targeted polymer lipid hybrid nanoparticles for in-vitro siRNA therapy in triple-negative breast cancer', Journal of Drug Delivery Science and Technology, 98, http://dx.doi.org/10.1016/j.jddst.2024.105911
    Journal articles | 2024
    Yang X; Bui TA; Mei H; Aksoy YA; Deng F; Hutvagner G; Deng W, 2024, 'Exploring the Potential and Challenges of CRISPR Delivery and Therapeutics for Genetic Disease Treatment', Advanced Functional Materials, 34, http://dx.doi.org/10.1002/adfm.202402630
    Journal articles | 2023
    Bui TA; Stafford N; Oceandy D, 2023, 'Genetic and Pharmacological YAP Activation Induces Proliferation and Improves Survival in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes', Cells, 12, http://dx.doi.org/10.3390/cells12172121
    Journal articles | 2023
    Mehta M; Bui TA; Yang X; Aksoy Y; Goldys EM; Deng W, 2023, 'Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development', ACS Materials Au, 3, pp. 600 - 619, http://dx.doi.org/10.1021/acsmaterialsau.3c00032
    Journal articles | 2022
    Nugroho AB; Stafford N; Zi M; Prehar S; Potter R; Kwon D; Kohar YS; Triastuti E; Bui TA; Cartwright EJ; Oceandy D, 2022, 'Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice', Jacc Basic to Translational Science, 7, pp. 859 - 875, http://dx.doi.org/10.1016/j.jacbts.2022.05.008
    Journal articles | 2020
    Pawitan JA; Bui TA; Mubarok W; Antarianto RD; Nurhayati RW; Dilogo IH; Oceandy D, 2020, 'Enhancement of the Therapeutic Capacity of Mesenchymal Stem Cells by Genetic Modification: A Systematic Review', Frontiers in Cell and Developmental Biology, 8, pp. 587776, http://dx.doi.org/10.3389/fcell.2020.587776
    Journal articles | 2019
    Nguyen BY; Ruiz-Velasco A; Bui T; Collins L; Wang X; Liu W, 2019, 'Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials', British Journal of Pharmacology, 176, pp. 4302 - 4318, http://dx.doi.org/10.1111/bph.14431
    Journal articles | 2019
    Triastuti E; Nugroho AB; Zi M; Prehar S; Kohar YS; Bui TA; Stafford N; Cartwright EJ; Abraham S; Oceandy D, 2019, 'Pharmacological inhibition of Hippo pathway, with the novel kinase inhibitor XMU-MP-1, protects the heart against adverse effects during pressure overload', British Journal of Pharmacology, 176, pp. 3956 - 3971, http://dx.doi.org/10.1111/bph.14795
    Journal articles | 2019
    Zi M; Stafford N; Prehar S; Baudoin F; Oceandy D; Wang X; Bui T; Shaheen M; Neyses L; Cartwright EJ, 2019, 'Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains', Current Research in Physiology, 1, pp. 1 - 10, http://dx.doi.org/10.1016/j.crphys.2019.10.001
    Journal articles | 2017
    Robertson A; Mohamed TMA; El Maadawi Z; Stafford N; Buy T; Lim DS; Cartwright EJ; Oceandy D, 2017, 'Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival', Stem Cell Research, 20, pp. 42 - 49, http://dx.doi.org/10.1016/j.scr.2017.02.011
    Journal articles | 1997
    Julier C; Delépine M; Keavney B; Terwilliger J; Davis S; Weeks DE; Bui T; Jeunemaître X; Velho G; Froguel P; Ratcliffe P; Corvol P; Soubrier F; Lathrop GM, 1997, 'Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10', Human Molecular Genetics, 6, pp. 2077 - 2086, http://dx.doi.org/10.1093/hmg/6.12.2077
  • Conference Abstracts | 2026
    Myooran J; Naylor J; March MK; Chróinín DNÍ; Bui TA; Bednorz N; Chen SH; Brady B, 2026, 'Understanding Patient and Clinician Perspectives in the HITH4Hips Trial: A Qualitative Study', in Australasian Journal on Ageing, Vol. 45, http://dx.doi.org/10.1111/ajag.70214

Rehabilitation in the home (RITH) after hip fracture: right care, right time, right place, right choice (RITH4Hips) - HCF 2024 Health Services Research Grant Program - AUD $493,233.00

 

Winner of Quality Awards in Health Research, South Western Sydney Local Health District, 2025

President’s Doctoral Scholar Award, University of Manchester, UK, 2014-2018

Award for Excellence, Faculty of Life Sciences, University of Manchester, UK 2014 

Outstanding Achievement Award, Faculty of Life Sciences, University of Manchester, UK, 2012

Silver Medal - 21st International Biology Olympiad 2010

First Prize - National Biology Olympiad, Vietnam 2010

1. Bui, T.A*., Lestari, B.*, Nugroho, A.B.*, Nguyen, B., Stafford, N., Prehar, S., Zi, M., Potter, R. Triastuti, E., Baudoin, F.M., D’Souza, A., Wang, X., Cartwright, E.J, Oceandy, D. Nature Communications. 2025, 16, 1650.

2. Hansen, S, Bui, T.A., Xu, X. and McGrath, K. Preclinical research models for evaluating the biocompatibility of bioresorbable metallic cardiovascular stents: A comparative review. Bioactive Materials. 2025, 54, 871-885.

3. Naylor, J.M., Bùi, T.A., Frost, S., et al. Foundations for Developing a Hospital in the Home Pathway Following Low Trauma Hip Fracture: Using Data to Inform the Path. Home Health Care Management & Practice. 2025, 0, 0.

4. Wang, Y., Bui, T.A., Yang, X. et al. Advancements in gene therapies targeting mutant KRAS in cancers. Cancer Metastasis Rev. 2025; 44, 24.

5. Bui, T.A.; Mei, H.; Sang, R.; Ortega, D.G.; Deng, W. Advancements and challenges in developing in vivo CAR T cell therapies for cancer treatment. EBioMedicine 2024, 106, 105266.

6. Bui, T.A.; Yang, X.; Mei, H.; Aksoy, Y.A.; Deng,F.; Hutvagner, G.; Deng., W. Exploring the Potential and Challenges of CRISPR Delivery and Therapeutics for Genetic Disease Treatment. Advanced Functional Materials 2024, 2402630.

7. Mehta, M.; Bui, T.A.;Care, A.; Deng, W. Targeted polymer lipid hybrid nanoparticles for in-vitro siRNA therapy in triple-negative breast cancer. Journal of Drug Delivery Science and Technology 2024, 98, 105911

8. Bui, T. A.; Stafford, N.; Oceandy, D., Genetic and Pharmacological YAP Activation Induces Proliferation and Improves Survival in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cells 2023, 12, 7.

9. Mehta, M.; Bui, T.A.;Yang, X.; Aksoy, Y.; Goldys, E. M.; Deng, W., Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development. ACS Materials Au 2023.

10. Nugroho, A. B.; Stafford, N.;Zi, M.; Prehar,S.; Potter, R.;Kwon,D.; Kohar, Y. S.; Triastuti, E.; Bui,T. A.;Cartwright, E. J.; Oceandy, D., Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice. JACC Basic Transl Sci 2022, 7 (9), 859-875.

11. Pawitan, J. A.; Bui, T. A.;Mubarok, W.; Antarianto, R. D.; Nurhayati, R. W.; Dilogo, I. H.; Oceandy, D., Enhancement of the Therapeutic Capacity of Mesenchymal Stem Cells by Genetic Modification: A Systematic Review. Front Cell Dev Biol 2020,8, 587776.

12. Nguyen, B. Y.; Ruiz-Velasco, A.; Bui, T.;Collins, L.; Wang, X.; Liu, W., Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials. Br J Pharmacol 2019,176 (22), 4302-4318.

13. Triastuti, E.; Nugroho, A. B.; Zi, M.;Prehar, S.; Kohar, Y. S.; Bui, T.A.;Stafford, N.; Cartwright, E. J.; Abraham, S.; Oceandy, D., Pharmacological inhibition of Hippo pathway, with the novel kinase inhibitor XMU-MP-1, protects the heart against adverse effects during pressure overload. Br J Pharmacol 2019, 176 (20), 3956-3971.

14. Zi, M.;Stafford, N.; Prehar, S.; Baudoin, F.;Oceandy, D.; Wang, X.; Bui, T.;Shaheen, M.; Neyses, L.; Cartwright, E. J., Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains. Curr Res Physiol 2019,1, 1-10.

15. Robertson, A.; Mohamed, T. M.; El Maadawi, Z.; Stafford, N.; Bui, T.; Lim, D. S.; Cartwright, E. J.; Oceandy, D., Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival. Stem Cell Res 2017,20, 42-49.