Dr Tina Naumovski

Dr Tina Naumovski

Senior Research Fellow
Medicine & Health
School of Clinical Medicine

Dr Valentina (Tina) Naumovski (BE (Hons), BSc (Chem.), PhD, GCULT, FHEA) is a Senior Research Fellow at South West Sydney Clinical Campuses. She is the operational lead and provides scientific methodology to a world-leading NSW Government-funded research program on medicinal cannabis clinical trials (Phase I/II/III) in advanced cancer addressing cachexia/anorexia. She currently leads a trans-Tasman group tasked with mapping a program of work to improve cachexia/anorexia syndrome under Palliative Care Clinical Studies Collaborative (PaCCSC) and building capacity to drive cancer symptom research into the future. Tina has led and co-designed the nation’s first survey on the experiences of health care professionals dealing with cancer cachexia and is designing an equivalent survey for patients with cancer suffering from anorexia.

  • Book Chapters | 2019
    2019, 'Cachexia/Anorexia and Feeding Difficulties', in Textbook of Palliative Care, Springer International Publishing, pp. 275 - 293, http://dx.doi.org/10.1007/978-3-319-77740-5_16
    Book Chapters | 2018
    2018, 'Cachexia/Anorexia and Feeding Difficulties', in Textbook of Palliative Care, Springer International Publishing, pp. 1 - 20, http://dx.doi.org/10.1007/978-3-319-31738-0_16-1
    Book Chapters | 2013
    Li GQ; Wong KH; Kam A; Zhou X; Omar EA; Alqahtani A; Li KM; Razmovski-Naumovski V; Chan K, 2013, 'Anti-Inflammatory Nutraceuticals and Herbal Medicines for the Management of Metabolic Syndrome', in Roy S; Bagchi D; Raychaudhuri SP (ed.), CHRONIC INFLAMMATION: MOLECULAR PATHOPHYSIOLOGY, NUTRITIONAL AND THERAPEUTIC INTERVENTIONS, CRC PRESS-TAYLOR & FRANCIS GROUP, pp. 337 - 350, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362830400025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Book Chapters | 2010
    Li GQ ; Naumovski V; Kimble B; Qiao VL; Tongkao-on W; Lin B; Mo S; Li KM, 2010, 'Quality control methods for herbal medicines in Comprehensive Bioactive Natural Products', in Gupta VK; Tanjela SC (ed.), Comprehensive Bioactive Natural Products, Studium Press, pp. 137 - 179
    Book Chapters | 2010
    Li GQ; Razmovski-Naumovski V; Omar E; Teoh AW; Song MK; Tongkao-on W; Nammi S; Mo S; Virgona N; Li KM; Naumovski V, 2010, 'Evaluation of biological activity in quality control of herbal medicines', in Gupta VK; Tanjela SC; Gupta BD (ed.), Comprehensive Bioactive Natural Products-Quality Control and Standardization,, pp. 181 - 215
    Book Chapters | 2008
    Naumovski V; Duke RK; Tran VH; Li GQ; Tattam BN; Roufogalis BD; Duke CC, 2008, 'Current methods in the isolation and characterization of saponins from Gynostemma pentaphyllum', in Epifano F (ed.), Current Trends in Phytochemistry, Research Signpost, pp. 283 - 309
  • Journal articles | 2023
    2023, 'A Retrospective Medical Record Review of Adults with Non-Cancer Diagnoses Prescribed Medicinal Cannabis', Journal of Clinical Medicine, 12, pp. 1483 - 1483, http://dx.doi.org/10.3390/jcm12041483
    Journal articles | 2023
    2023, 'Health care professionals’ experiences of dealing with cancer cachexia', International Journal of Clinical Oncology, 28, pp. 592 - 602, http://dx.doi.org/10.1007/s10147-023-02300-6
    Journal articles | 2022
    2022, 'A comparative study of Salvia miltiorrhiza Radix & Rhizoma raw material and granule products using chromatographic analysis and antioxidant activity', Journal of Traditional Chinese Medical Sciences, 9, pp. 311 - 320, http://dx.doi.org/10.1016/j.jtcms.2022.06.004
    Journal articles | 2022
    2022, 'Appetite-Related Distress Is Burdensome in the Last Sixty Days of Life of People Receiving Palliative Care: A National Longitudinal Consecutive Cohort Study', Journal of Palliative Medicine, 25, pp. 636 - 642, http://dx.doi.org/10.1089/jpm.2021.0462
    Journal articles | 2022
    2022, 'Assessing the quantification of acetylation in konjac glucomannan via ATR-FTIR and solid-state NMR spectroscopy', Carbohydrate Polymers, 291, http://dx.doi.org/10.1016/j.carbpol.2022.119659
    Journal articles | 2022
    2022, 'Defining the trials nurses’ role in operationalising a medicinal cannabis clinical trial', Collegian, 29, pp. 370 - 378, http://dx.doi.org/10.1016/j.colegn.2021.10.003
    Journal articles | 2022
    2022, 'Efficacy of medicinal cannabis for appetite-related symptoms in people with cancer: A systematic review', Palliative Medicine, 36, pp. 912 - 927, http://dx.doi.org/10.1177/02692163221083437
    Journal articles | 2022
    2022, 'Polysaccharide Peptide Extract From Coriolus versicolor Increased Tmax of Tamoxifen and Maintained Biochemical Serum Parameters, With No Change in the Metabolism of Tamoxifen in the Rat', Frontiers in Pharmacology, 13, http://dx.doi.org/10.3389/fphar.2022.857864
    Journal articles | 2022
    2022, 'Synergistic Effects of Natural Product Combinations in Protecting the Endothelium Against Cardiovascular Risk Factors', Journal of Evidence-Based Integrative Medicine, 27, http://dx.doi.org/10.1177/2515690X221113327
    Journal articles | 2021
    2021, 'Attenuation of methylglyoxal-induced glycation and cellular dysfunction in wound healing by Centella cordifolia', Saudi Journal of Biological Sciences, 28, pp. 813 - 824, http://dx.doi.org/10.1016/j.sjbs.2020.11.016
    Journal articles | 2020
    2020, 'Alpha-amylase and alpha-glucosidase enzyme inhibition and antioxidant potential of 3-oxolupenal and katononic acid isolated from Nuxia oppositifolia', Biomolecules, 10, pp. 61 - 61, http://dx.doi.org/10.3390/biom10010061
    Journal articles | 2020
    2020, 'Chromatographic, Chemometric and Antioxidant Assessment of the Equivalence of Granules and Herbal Materials of Angelicae sinensis Radix.', Medicines (Basel), 7, http://dx.doi.org/10.3390/medicines7060035
    Journal articles | 2019
    2019, 'Atorvastatin Improves Hepatic Lipid Metabolism and Protects Renal Damage in Adenine-Induced Chronic Kidney Disease in Sprague-Dawley Rats', BioMed Research International, 2019, pp. 1 - 10, http://dx.doi.org/10.1155/2019/8714363
    Journal articles | 2019
    2019, 'Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats', BMC Nephrology, 20, pp. 431, http://dx.doi.org/10.1186/s12882-019-1621-6
    Journal articles | 2019
    2019, 'Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells', BMC Complementary and Alternative Medicine, 19, pp. 50, http://dx.doi.org/10.1186/s12906-019-2458-z
    Journal articles | 2018
    Purpura M; Lowery RP; Wilson JM; Mannan H; Münch G; Razmovski-Naumovski V, 2018, 'Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects', European Journal of Nutrition, 57, pp. 929 - 938, http://dx.doi.org/10.1007/s00394-016-1376-9
    Journal articles | 2018
    2018, '(R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro', BMC Complementary and Alternative Medicine, 18, http://dx.doi.org/10.1186/s12906-017-2076-6
    Journal articles | 2018
    2018, 'Attenuation of glucose‐induced myoglobin glycation and the formation of advanced glycation end products (AGEs) by (R)‐α‐lipoic acid in vitro', Biomolecules, 8, pp. 9 - 9, http://dx.doi.org/10.3390/biom8010009
    Journal articles | 2017
    Alqahtani A; Cho JL; Wong KH; Li KM; Razmovski-Naumovski V; Li GQ, 2017, 'Differentiation of three centella species in Australia as inferred from morphological characteristics, ISSR molecular fingerprinting and phytochemical composition', Frontiers in Plant Science, 8, http://dx.doi.org/10.3389/fpls.2017.01980
    Journal articles | 2017
    Wong KH; Li GQ; Li KM; Razmovski-Naumovski V; Chan K, 2017, 'Optimisation of Pueraria isoflavonoids by response surface methodology using ultrasonic-assisted extraction', Food Chemistry, 231, pp. 231 - 237, http://dx.doi.org/10.1016/j.foodchem.2017.03.068
    Journal articles | 2017
    2017, 'Chronic treatment of (R)-α-lipoic acid reduces blood glucose and lipid levels in high-fat diet and low-dose streptozotocin-induced metabolic syndrome and type 2 diabetes in Sprague-Dawley rats', Pharmacology Research and Perspectives, 5, pp. e00306 - e00306, http://dx.doi.org/10.1002/prp2.306
    Journal articles | 2017
    2017, 'Synergistic Effects of Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Angiogenesis Behavior in EAhy 926 Cells.', Medicines (Basel), 4, pp. 85 - 85, http://dx.doi.org/10.3390/medicines4040085
    Journal articles | 2016
    Zhou X; Razmovski-Naumovski V; Chang D; Li C; Kam A; Low M; Bensoussan A; Chan K, 2016, 'Synergistic Effects of Danshen (Salvia Miltiorrhiza Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Inhibiting Inflammation Mediators in RAW264.7 Cells', BioMed Research International, 2016, http://dx.doi.org/10.1155/2016/5758195
    Journal articles | 2016
    Zhou X; Seto SW; Chang D; Kiat H; Razmovski-Naumovski V; Chan K; Bensoussan A, 2016, 'Synergistic effects of Chinese herbal medicine: A comprehensive review of methodology and current research', Frontiers in Pharmacology, 7, http://dx.doi.org/10.3389/fphar.2016.00201
    Journal articles | 2015
    Alqahtani A; Tongkao-On W; Li KM; Razmovski-Naumovski V; Chan K; Li GQ, 2015, 'Seasonal Variation of Triterpenes and Phenolic Compounds in Australian Centella asiatica (L.) Urb', Phytochemical Analysis, 26, pp. 436 - 443, http://dx.doi.org/10.1002/pca.2578
    Journal articles | 2015
    Chan K; Hu XY; Razmovski-Naumovski V; Robinson N, 2015, 'Challenges and opportunities of integrating traditional Chinese medicine into mainstream medicine: A review of the current situation', European Journal of Integrative Medicine, 7, pp. 67 - 75, http://dx.doi.org/10.1016/j.eujim.2014.12.006
    Journal articles | 2015
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Grau GE; Li GQ, 2015, 'Curcumin reduces tumour necrosis factor-enhanced annexin v-positive microparticle release in human vascular endothelial cells', Journal of Pharmacy and Pharmaceutical Sciences, 18, pp. 424 - 433, http://dx.doi.org/10.18433/j3zc8g
    Journal articles | 2015
    Kam A; Razmovski-Naumovski V; Zhou X; Truong J; Chan K, 2015, 'Nucleoside transport inhibition by dipyridamole prevents angiogenesis impairment by homocysteine and adenosine', Journal of Pharmacy and Pharmaceutical Sciences, 18, pp. 871 - 881, http://dx.doi.org/10.18433/j3tg88
    Journal articles | 2015
    Wong KH; Razmovski-Naumovski V; Li KM; Li GQ; Chan K, 2015, 'Comparing morphological, chemical and anti-diabetic characteristics of Puerariae Lobatae Radix and Puerariae Thomsonii Radix', Journal of Ethnopharmacology, 164, pp. 53 - 63, http://dx.doi.org/10.1016/j.jep.2014.12.050
    Journal articles | 2015
    Wong KH; Razmovski-Naumovski V; Li KM; Li GQ; Chan K, 2015, 'The quality control of two Pueraria species using Raman spectroscopy coupled with partial least squares analysis', Journal of Raman Spectroscopy, 46, pp. 361 - 368, http://dx.doi.org/10.1002/jrs.4652
    Journal articles | 2015
    Zhou X; Razmovski-Naumovski V; Chan K, 2015, 'A multivariate analysis on the comparison of raw notoginseng (Sanqi) and its granule products by thin-layer chromatography and ultra-performance liquid chromatography', Chinese Medicine (United Kingdom), 10, http://dx.doi.org/10.1186/s13020-015-0040-2
    Journal articles | 2014
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Li GQ, 2014, 'Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities', International Journal of Cardiology, 171, pp. 231 - 242, http://dx.doi.org/10.1016/j.ijcard.2013.12.020
    Journal articles | 2014
    Wong KH; Razmovski-Naumovski V; Li KM; Li GQ; Chan K, 2014, 'Differentiating Puerariae Lobatae Radix and Puerariae Thomsonii Radix using HPTLC coupled with multivariate classification analyses', Journal of Pharmaceutical and Biomedical Analysis, 95, pp. 11 - 19, http://dx.doi.org/10.1016/j.jpba.2014.02.007
    Journal articles | 2013
    Alqahtani A; Hamid K; Kam A; Wong KH; Abdelhak Z; Razmovski-Naumovski V; Chan K; Li KM; Groundwater PW; Li GQ, 2013, 'The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications', Current Medicinal Chemistry, 20, pp. 908 - 931, http://dx.doi.org/10.2174/092986713805219082
    Journal articles | 2013
    Chong CM; Zhou ZY; Razmovski-Naumovski V; Cui GZ; Zhang LQ; Sa F; Hoi PM; Chan K; Lee SM Y, 2013, 'Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish', Neuroscience Letters, 543, pp. 121 - 125, http://dx.doi.org/10.1016/j.neulet.2013.02.069
    Journal articles | 2013
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Li GQ, 2013, 'Variability of the polyphenolic content and antioxidant capacity of methanolic extracts of pomegranate peel', Natural Product Communications, 8, pp. 707 - 710, http://dx.doi.org/10.1177/1934578x1300800607
    Journal articles | 2013
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Shi J; Chan K; Li GQ, 2013, 'A comparative study on the inhibitory effects of different parts and chemical constituents of pomegranate on α-amylase and α-glucosidase', Phytotherapy Research, 27, pp. 1614 - 1620, http://dx.doi.org/10.1002/ptr.4913
    Journal articles | 2013
    Kim EJ Y; Chen Y; Huang JQ; Li KM; Razmovski-Naumovski V; Poon J; Chan K; Roufogalis BD; McLachlan AJ; Mo SL; Yang D; Yao M; Liu Z; Liu J; Li GQ, 2013, 'Evidence-based toxicity evaluation and scheduling of Chinese herbal medicines', Journal of Ethnopharmacology, 146, pp. 40 - 61, http://dx.doi.org/10.1016/j.jep.2012.12.027
    Journal articles | 2013
    Li GQ; Kam A; Wong KH; Zhou X; Omar EA; Alqahtani A; Li KM; Razmovski-Naumovski V; Chan K, 2013, 'Herbal medicines for the management of diabetes', Advances in Experimental Medicine and Biology, 771, pp. 396 - 413, http://dx.doi.org/10.1007/978-1-4614-5441-0_28
    Journal articles | 2013
    Wong KH; Razmovski-Naumovski V; Li KM; Li GQ; Chan K, 2013, 'Differentiation of Pueraria lobata and Pueraria thomsonii using partial least square discriminant analysis (PLS-DA)', Journal of Pharmaceutical and Biomedical Analysis, 84, pp. 5 - 13, http://dx.doi.org/10.1016/j.jpba.2013.05.040
    Journal articles | 2012
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Li GQ, 2012, 'Combination of TNF-α, homocysteine and adenosine exacerbated cytotoxicity in human cardiovascular and cerebrovascular endothelial cells', Cellular Physiology and Biochemistry, 30, pp. 805 - 814, http://dx.doi.org/10.1159/000341459
    Journal articles | 2012
    Kam A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Li Y; Li GQ, 2012, 'The protective effects of natural products on blood-brain barrier breakdown', Current Medicinal Chemistry, 19, pp. 1830 - 1845, http://dx.doi.org/10.2174/092986712800099794
    Journal articles | 2011
    Wong KH; Li GQ; Li KM; Razmovski-Naumovski V; Chan K, 2011, 'Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, 134, pp. 584 - 607, http://dx.doi.org/10.1016/j.jep.2011.02.001
    Journal articles | 2010
    Omara EA; Kam A; Alqahtania A; Li KM; Razmovski-Naumovski V; Nammi S; Chan K; Roufogalis BD; Li GQ, 2010, 'Herbal medicines and nutraceuticals for diabetic vascular complications: Mechanisms of action and bioactive phytochemicals', Current Pharmaceutical Design, 16, pp. 3776 - 3807, http://dx.doi.org/10.2174/138161210794455076
    Journal articles | 2007
    Hesse C; Razmovski-Naumovski V; Duke CC; Davies NM; Roufogalis BD, 2007, 'Phytopreventative effects of Gynostemma pentaphyllum against acute indomethacin-induced gastrointestinal and renal toxicity in rats', Phytotherapy Research, 21, pp. 523 - 530, http://dx.doi.org/10.1002/ptr.2086
    Journal articles | 2006
    Huang TH W; Li Y; Razmovski-Naumovski V; Tran VH; Li GQ; Duke CC; Roufogalis BD, 2006, 'Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway', Journal of Biomedical Science, 13, pp. 535 - 548, http://dx.doi.org/10.1007/s11373-006-9076-8
    Journal articles | 2005
    Huang TH W; Razmovski-Naumovski V; Kota BP; Lin DS H; Roufogalis BD, 2005, 'The pathophysiological function of peroxisome proliferator-activated receptor-γ in lung-related diseases', Respiratory Research, 6, http://dx.doi.org/10.1186/1465-9921-6-102
    Journal articles | 2005
    Huang TH W; Razmovski-Naumovski V; Salam NK; Duke RK; Tran VH; Duke CC; Roufogalis BD, 2005, 'A novel LXR-α activator identified from the natural product Gynostemma pentaphyllum', Biochemical Pharmacology, 70, pp. 1298 - 1308, http://dx.doi.org/10.1016/j.bcp.2005.07.033
    Journal articles | 2005
    Razmovski-Naumovski V; Duke RK; Turner P; Duke CC, 2005, '(20S)-2α,3β,12β-Trihydroxydammar-24-ene 20-O-β-D-glucopyranoside (Gynosaponin TN1) as the 2.5-methanol solvate', Acta Crystallographica Section E: Structure Reports Online, 61, http://dx.doi.org/10.1107/S1600536805009773
    Journal articles | 2005
    Razmovski-Naumovski V; Huang TH W; Tran VH; Li GQ; Duke CC; Roufogalis BD, 2005, 'Chemistry and pharmacology of Gynostemma pentaphyllum', Phytochemistry Reviews, 4, pp. 197 - 219, http://dx.doi.org/10.1007/s11101-005-3754-4
    Journal articles | 2005
    Razmovski-Naumovski V; Li GQ; Duke CC, 2005, 'Gynostemma pentaphyllum cultivation in Sydney, Australia and its comparison with products from China.', Journal of Applied Horticulture, 7, pp. 99 - 104
    Journal articles | 2005
    2005, 'Herbal or natural medicine as modulators of peroxisome proliferator activated receptors and related nuclear receptors for therapy of metabolic syndrome.', Basic & Clinical Pharmacology & Toxicology, 96, pp. 3 - 14, http://dx.doi.org/10.1111/j.1742-7843.2005.pto960102.x
    Journal articles | 2000
    2000, 'A new method for simultaneous immunodetection and morphologic identification of individual sources of pollen allergens.', Journal of Allergy & Clinical Immunology, 105, pp. 725 - 731, http://dx.doi.org/10.1067/mai.2000.105222
    Journal articles | 1998
    Razmovski V; O'meara T; Hjelmroos M; Marks G; Tovey E, 1998, 'Adhesive tapes as capturing surfaces in Burkard sampling', Grana, 37, pp. 305 - 310, http://dx.doi.org/10.1080/00173139809362683
  • Conference Abstracts | 2014
    Ghelani H; Naumovski V; Nammi S, 2014, 'Protective Role of Alpha-Lipoic Acid on Myoglobin Glycation in the Development of Diabetes-Induced Myocardial Infarction', in INDIAN JOURNAL OF PHARMACOLOGY, MEDKNOW PUBLICATIONS & MEDIA PVT LTD, Vol. 46, pp. S18 - S18, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000348432700060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Razmovski-Naumovski V; Tongkao-on W; Kimble B; Qiao VL; Beilun L; Li KM; Roufogalis B; Depo Y; Meicun Y; Li GQ, 2010, 'Multiple Chromatographic and Chemometric Methods for Quality Standardisation of Chinese Herbal Medicines', in World Science and Technology, Elsevier BV, pp. 99 - 106, http://dx.doi.org/10.1016/s1876-3553(11)60003-3

Tina is one of very few researchers in the world with a multidisciplinary approach spanning the cultivation, analytical (isolating and identifying compounds), pharmacological/preclinical (mechanism of action predominantly in diabetes/metabolic syndrome, drug interactions, pharmacokinetics) and clinical (medicinal cannabis for symptom relief in palliative care) and qualitative research of bioactive compounds.