Dr Toby Nicholas Trahair
Conjoint Lecturer

Dr Toby Nicholas Trahair

BSc(Med) Hons I MBBS Hons I PhD FRACP

medicine-health
Sch Women's&Children's Health

Dr Toby Trahair is a Conjoint Lecturer in the School of Women’s & Children’s Health, Faculty of Medicine, UNSW. He has appointments as a staff specialist in paediatric haematology and oncology at the Kids Cancer Centre, Sydney Children’s Hospital and a Clinical Research Fellow at the Children’s Cancer Institute.

Dr Toby Trahair is a paediatric haematologist & oncologist who has practiced as a Staff Specialist at the Kids Cancer Centre since 2006.  In addition, Toby is a clinical research fellow at Children's Cancer Institute with 15 years of postdoctoral experience, commencing with a post-doctoral fellowship at the Stem Cell Research Laboratory, Peter MacCallum Cancer Centre before moving to CCI in 2006.

Toby is involved in clinical trials research as the lead Australian investigator on the international SIOPEN trial for high risk neuroblastoma and an investigator on the early phase I/II Ceritinib trial for children and teenagers with ALK-rearranged malignancies. Dr Trahair has served as executive treasurer on the Executive Council of the Australian and New Zealand Children's Haematology and Oncology Group (ANZCHOG) since 2010.

Toby has active research interests in the management of acute lymphoblastic leukaemia including techniques of minimal residual disease detection, mechanisms and models of drug resistance in ALL, haematopoietic stem cell transplantation, ALK rearranged tumours and personalised therapy for high risk tumours. He currently supervises PhD students, the ERASE project which is identifying clinical and genetic risk factors for treatment-related side effects in ALL patients.

Current research projects include:

  1. Predictive clinical and genetic factors for the side effects of chemotherapy in children treated for acute lymphoblastic leukaemia (The ERASE and ASSET projects). A collaborative project with Prof G Marshall, Dr L Dalla-Pozza & Dr Marion Mateos. A project funded by the Kids Cancer Alliance and supported by the Australian and New Zealand Children’s Haematology & Oncology Group.
  2. Finding new treatments for ALK+ve inflammatory myofibroblastic tumours. A collaborative project with Dr Karen MacKenzie at the Children’s Cancer Institute. A project supported by the Rory Williams Fund.
  3. Developing xenograft models of high risk neuroblastoma. A project in collaboration with Dr Jamie Fletcher, Children’s Cancer Institute and funded by the Kids Cancer Alliance.
Phone
+612 9382 2970
Location
Kids Cancer Centre Sydney Children's Hospital High Street Randwick NSW 2031

Publications

  • Journal articles | 2021
    Dr Toby Nicholas Trahair
    Schilstra CE; Sansom-Daly UM; Schaffer M; Fardell JE; Anazodo AC; McCowage G; Fletcher J; Marshall GM; Buchhorn-White J; Evtushenko M; Trahair TN; Ellis SJ, 2021, '"We Have All This Knowledge to Give, So Use Us as a Resource": Partnering with Adolescent and Young Adult Cancer Survivors to Determine Consumer-Led Research Priorities', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, http://dx.doi.org/10.1089/jayao.2021.0052
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Schilstra CE; Fardell JE; Ellis SJ; Jones KM; Anazodo AC; Trahair TN; Lah S; Cohn RJ; Wakefield CE; Sansom-Daly UM, 2021, 'Social Anxiety Symptoms in Survivors of Childhood and Adolescent Cancer', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, http://dx.doi.org/10.1089/jayao.2021.0050
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Schilstra CE; Fardell JE; Burns MA; Ellis SJ; Anazodo AC; Trahair TN; Sansom-Daly UM, 2021, 'Determinants of social functioning among adolescents and young adults with cancer: A systematic review', Psycho-Oncology, http://dx.doi.org/10.1002/pon.5740
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Mahajan P; Casanova M; Ferrari A; Fordham A; Trahair T; Venkatramani R, 2021, 'Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges', Current Problems in Cancer, http://dx.doi.org/10.1016/j.currproblcancer.2021.100768
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Berlanga P; Pasqualini C; Pötschger U; Sangüesa C; Castellani MR; Cañete A; Luksch R; Elliot M; Schreier G; Kropf M; Morgenstern D; Papadakis V; Ash S; Ruud E; Brock P; Wieczorek A; Kogner P; Trahair T; Ambros P; Boterberg T; Castel V; Valteau-Couanet D; Ladenstein R, 2021, 'Central nervous system relapse in high-risk stage 4 neuroblastoma: The HR-NBL1/SIOPEN trial experience', European Journal of Cancer, vol. 144, pp. 1 - 8, http://dx.doi.org/10.1016/j.ejca.2020.10.020
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Sutton R; Pozza LD; Khaw SL; Fraser C; Revesz T; Chamberlain J; Mitchell R; Trahair TN; Bateman CM; Venn NC; Law T; Ong E; Heatley SL; McClure BJ; Meyer C; Marschalek R; Henderson MJ; Cross S; White DL; Kotecha RS, 2021, 'Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab', Pediatric Blood and Cancer, vol. 68, pp. e28922, http://dx.doi.org/10.1002/pbc.28922
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, vol. 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Lapirow D; La Gerche A; Toro C; Masango E; Costello B; Porello E; Ludlow L; Marshall G; Trahair T; Mateos M; Lewin J; Byrne J; Boutros R; Manudhane R; Heath J; Ayer J; Gabriel M; Walwyn T; Saundankar J; Forsey J; Le H; Mason K; Celermajer D; Downie P; Walker R; Holland L; Martin M; McLeman L; Diamond Y; Marcocci M; Donath S; Cheung M; Elliott DA; Conyers R, 2021, 'The Australia and New Zealand Cardio-Oncology Registry: evaluation of chemotherapy-related cardiotoxicity in a national cohort of paediatric cancer patients', Internal Medicine Journal, vol. 51, pp. 229 - 234, http://dx.doi.org/10.1111/imj.14719
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, vol. 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Andrés-Jensen L; Attarbaschi A; Bardi E; Barzilai-Birenboim S; Bhojwani D; Hagleitner MM; Halsey C; Harila-Saari A; van Litsenburg RRL; Hudson MM; Jeha S; Kato M; Kremer L; Mlynarski W; Möricke A; Pieters R; Piette C; Raetz E; Ronceray L; Toro C; Grazia Valsecchi M; Vrooman LM; Weinreb S; Winick N; Schmiegelow K; Adams MR; Baust K; Boesten T; Calaminus G; Conyers R; Darlington AS; de Ville M; Escherich G; Hou JY; Huang TH; Hudson M; Jenney M; Krawczuk-Rybak M; Kremer L; Lautem M; Liu HC; Lopez Lopez E; Mateos M; Muszynska-Roslan K; Niinimaki R; Trahair T; Valsecchi MG; van der Sluis I; Wiener A; Yano M; Yeh TC; Zapotocka E, 2021, 'Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia', The Lancet Haematology, vol. 8, pp. e513 - e523, http://dx.doi.org/10.1016/S2352-3026(21)00136-8
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Michniewicz F; Saletta F; Rouaen JRC; Hewavisenti RV; Mercatelli D; Cirillo G; Giorgi FM; Trahair T; Ziegler D; Vittorio O, 2021, 'Copper: An Intracellular Achilles’ Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics', ChemMedChem, http://dx.doi.org/10.1002/cmdc.202100172
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Garaventa A; Poetschger U; Valteau-Couanet D; Luksch R; Castel V; Elliott M; Ash S; Chan GCF; Laureys G; Beck-Popovic M; Vettenranta K; Balwierz W; Schroeder H; Owens C; Cesen M; Papadakis V; Trahair T; Schleiermacher G; Ambros P; Sorrentino S; Pearson ADJ; Ladenstein RL, 2021, 'Randomized Trial of Two Induction Therapy Regimens for High-Risk Neuroblastoma: HR-NBL1.5 International Society of Pediatric Oncology European Neuroblastoma Group Study.', J Clin Oncol, pp. JCO2003144, http://dx.doi.org/10.1200/JCO.20.03144
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Mateos MK; Marshall GM; Barbaro PM; Quinn MC; George C; Mayoh C; Sutton R; Revesz T; Giles JE; Barbaric D; Alvaro F; Mechinaud F; Catchpoole D; Lawson JA; Chenevix-Trench G; MacGregor S; Kotecha RS; Dalla-Pozza L; Trahair TN, 2021, 'Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia.', Haematologica, http://dx.doi.org/10.3324/haematol.2020.268565
    Journal articles | 2021
    Dr Toby Nicholas Trahair
    Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', NPJ PRECISION ONCOLOGY, vol. 5, http://dx.doi.org/10.1038/s41698-021-00145-8
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, vol. 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Ladenstein R; Pötschgerulrike.poetschger@ccri.at U; Valteau-couanet D; Luksch R; Castel V; Ash S; Laureys G; Brock P; Michon JM; Owenscormac.owens@olchc.ie C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck-popovic M; Schreier G; Loibner H; Ambros P; Holmes K; Castellani MR; Gaze MN; Garaventa A; Pearson ADJ; Lode HN, 2020, 'Investigation of the role of dinutuximab beta-based immunotherapy in the siopen high-risk neuroblastoma 1 trial (HR-NBL1)', Cancers, vol. 12, http://dx.doi.org/10.3390/cancers12020309
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Xie J; Span M; van Maarseveen E; Langenhorst J; Boddy AV; Sia KCS; Sutton R; Venn N; Punt AM; Tyrrell V; Haber M; Trahair T; Lau L; Marshall GM; Lock RB, 2020, 'Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia', Pediatric Blood and Cancer, vol. 67, pp. e28133, http://dx.doi.org/10.1002/pbc.28133
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Mateos MK; Tulstrup M; Quinn MCJ; Tuckuviene R; Marshall GM; Gupta R; Mayoh C; Wolthers BO; Barbaro PM; Ruud E; Sutton R; Huttunen P; Revesz T; Trakymiene SS; Barbaric D; Tedgård U; Giles JE; Alvaro F; Jonsson OG; Mechinaud F; Saks K; Catchpoole D; Kotecha RS; Dalla-Pozza L; Chenevix-Trench G; Trahair TN; Macgregor S; Schmiegelow K, 2020, 'Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children', Cancers, vol. 12, http://dx.doi.org/10.3390/cancers12051285
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Fordham AM; Xie J; Gifford AJ; Wadham C; Morgan LT; Mould EVA; Fadia M; Zhai L; Massudi H; Ali ZS; Marshall GM; Lukeis RE; Fletcher JI; MacKenzie KL; Trahair TN, 2020, 'CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma', British Journal of Cancer, vol. 123, pp. 1101 - 1113, http://dx.doi.org/10.1038/s41416-020-0996-2
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Holmes K; Pötschger U; Pearson ADJ; Sarnacki S; Cecchetto G; Gomez-Chacon J; Squire R; Freud E; Bysiek A; Matthyssens LE; Metzelder M; Monclair T; Stenman J; Rygl M; Rasmussen L; Joseph JM; Irtan S; Avanzini S; Godzinski J; Björnland K; Elliott M; Luksch R; Castel V; Ash S; Balwierz W; Laureys G; Ruud E; Papadakis V; Malis J; Owens C; Schroeder H; Beck-Popovic M; Trahair T; de Lacerda AF; Ambros PF; Gaze MN; McHugh K; Valteau-Couanet D; Ladenstein RL, 2020, 'Influence of Surgical Excision on the Survival of Patients with Stage 4 High-Risk Neuroblastoma: A Report from the HR-NBL1/SIOPEN Study', Journal of Clinical Oncology, vol. 38, pp. 2902 - 2915, http://dx.doi.org/10.1200/JCO.19.03117
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Berry NK; Scott RJ; Sutton R; Law T; Trahair TN; Dalla-Pozza L; Ritchie P; Barbaric D; Enjeti AK, 2020, 'Enrichment of atypical hyperdiploidy and IKZF1 deletions detected by SNP-microarray in high-risk Australian AIEOP-BFM B-cell acute lymphoblastic leukaemia cohort', Cancer Genetics, vol. 242, pp. 8 - 14, http://dx.doi.org/10.1016/j.cancergen.2020.01.051
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Kamili A; Gifford AJ; Li N; Mayoh C; Chow S-O; Failes TW; Eden GL; Cadiz R; Xie J; Lukeis RE; Norris MD; Haber M; McCowage GB; Arndt GM; Trahair TN; Fletcher JI, 2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer, http://dx.doi.org/10.1038/s41416-019-0682-4
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Kamili A; Atkinson C; Trahair TN; Fletcher JI, 2020, 'Mouse models of high-risk neuroblastoma', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-020-09855-0
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Lee S; Nath CE; Balzer BWR; Lewis CR; Trahair TN; Anazodo AC; Shaw PJ, 2020, 'An HPLC-PDA Method for Determination of Alectinib Concentrations in the Plasma of an Adolescent', Acta Chromatographica, vol. 32, pp. 166 - 169, http://dx.doi.org/10.1556/1326.2019.00578
    Journal articles | 2020
    Dr Toby Nicholas Trahair
    Mckenna JE; Trahair T, 2020, 'Bronchial carcinoid tumour identified as the cause for recurrent pneumonia in a 10-year-old boy', Journal of Paediatrics and Child Health, vol. 56, pp. 642 - 644, http://dx.doi.org/10.1111/jpc.14623
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, vol. 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410, http://dx.doi.org/10.1038/s41375-018-0354-z
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Boutros R; Catchpoole D; Collins K; Cross S; Downie P; Drinkwater C; Fletcher J; Gottardo N; Hunter S; Kirby M; Ludlow L; MacNish M; Maybury M; Moore A; Morrin H; Purdy S; Revesz T; Saffery R; Strong R; Trahair T; Wood A; Byrne J, 2019, 'The Australian and New Zealand Children's Haematology/Oncology Group Biobanking Network', Biopreservation and Biobanking, vol. 17, pp. 95 - 97, http://dx.doi.org/10.1089/bio.2019.0013
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Trahair T; Gifford AJ; Fordham A; Mayoh C; Fadia M; Lukeis R; Wood AC; Valvi S; Walker RD; Blackburn J; Heyer EE; Mercer TR; Barbaric D; Marshall GM; MacKenzie KL, 2019, 'Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors', JCO Precision Oncology, vol. 3, pp. 1 - 11, http://dx.doi.org/10.1200/PO.18.00297
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Mateos MK; Trahair TN; Mayoh C; Barbaro PM; Sutton R; Revesz T; Barbaric D; Giles JE; Alvaro F; Mechinaud F; Catchpoole D; Kotecha RS; Dalla-Pozza L; Quinn MCJ; MacGregor S; Chenevix-Trench G; Marshall GM, 2019, 'Risk factors for symptomatic venous thromboembolism during therapy for childhood acute lymphoblastic leukemia', Thrombosis Research, vol. 178, pp. 132 - 138, http://dx.doi.org/10.1016/j.thromres.2019.04.011
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Greenwood M; Trahair T; Osborn M; Sutton R; Kwan J; Mapp S; Burt A; Jager A; Frampton C; Wei A; Bradstock K; Dalla-Pozza L, 2019, 'PS938 INTENSIVE PAEDIATRIC THERAPY IS AS DELIVERABLE IN ADOLESCENTS AND YOUNG ADULTS AS CHILDREN WITH ALL - PRELIMINARY RESULTS OF THE AUSTRALASIAN LEUKAEMIA AND LYMPHOMA GROUP (ALLG) ALL06 STUDY', HemaSphere, vol. 3, pp. 422 - 422, http://dx.doi.org/10.1097/01.hs9.0000562024.31781.2a
    Journal articles | 2019
    Dr Toby Nicholas Trahair
    Yeung DT; Greenwood M; Rhen J; Heatley SL; McClure B; Eadie LN; Breen J; Schutz CS; Trahair TN; Wei AH; Dalla-Pozza L; Sutton R; Bradstock KF; Osborn MP; White DL, 2019, 'High Risk Genomic Alterations Identified at the Time of Diagnosis Are Strongly Associated with MRD and Subsequent Poor Outcomes in AYA ALL Patients Treated on a Pediatric Inspired Chemotherapy Regimen', Blood, vol. 134, pp. 3949 - 3949, http://dx.doi.org/10.1182/blood-2019-127788
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Matsuno R; Gifford AJ; Fang J; Warren M; Lukeis RE; Trahair T; Sugimoto T; Marachelian A; Asgharzadeh S; Maris JM; Ikegaki N; Shimada H, 2018, 'Rare MYC-amplified Neuroblastoma With Large Cell Histology', Pediatric and Developmental Pathology, vol. 21, pp. 461 - 466, http://dx.doi.org/10.1177/1093526617749670
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, vol. 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, vol. 40, pp. 541 - 547, http://dx.doi.org/10.1097/MPH.0000000000001215
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Balzer BW; Loo C; Lewis CR; Trahair TN; Anazodo A, 2018, 'Adenocarcinoma of the Lung in Childhood and Adolescence: a systematic review.', J Thorac Oncol., vol. 18, pp. 33035 - 33035, http://dx.doi.org/10.1016/j.jtho.2018.08.2020.
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Garaventa A; Poetschger U; Valteau-Couanet D; Castel V; Elliott M; Ash S; Chan GC-F; Laureys G; Beck Popovic M; Vettenranta K; Balwierz W; Schroeder H; Owens C; Cesen M; Papadakis V; Trahair T; Luksch R; Schleiermacher G; Ambros PF; Ladenstein RL, 2018, 'The randomised induction for high-risk neuroblastoma comparing COJEC and N5-MSKCC regimens: Early results from the HR-NBL1.5/SIOPEN trial.', Journal of Clinical Oncology, vol. 36, pp. 10507 - 10507, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.10507
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Balzer B; Loo C; Wegner E; Nath C; Lee S; Smith C; Lewis C; Trahair T; Anazodo A, 2018, 'Alectinib is effective, safe and tolerable in an adolescent with stage IVB ALK-rearranged adenocarcinoma of the lung.', Pediatric Hematology-Oncology, pp. 1 - 7, http://dx.doi.org/10.1080/08880018.2018.1541492
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Ladenstein R; Pötschger U; Valteau-Couanet D; Luksch R; Castel V; Yaniv I; Laureys G; Brock P; Michon JM; Owens C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck Popovic M; Schreier G; Loibner H; Ambros P; Holmes K; Castellani MR; Gaze MN; Garaventa A; Pearson ADJ; Lode HN, 2018, 'Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial', The Lancet Oncology, vol. 19, pp. 1617 - 1629, http://dx.doi.org/10.1016/S1470-2045(18)30578-3
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Ladenstein RL; Poetschger U; Valteau Couanet D; Gray J; Luksch R; Castel V; Ash S; Laureys G; Owens C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck Popovic M; Loibner H; Schreier G; Ambros PF; Sarnacki S; Boterberg T; Lode HN, 2018, 'Immunotherapy with anti-GD2 antibody ch14.18/CHO±IL2 within the HR-NBL1/SIOPEN trial to improve outcome of high-risk neuroblastoma patients compared to historical controls.', Journal of Clinical Oncology, vol. 36, pp. 10539 - 10539, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.10539
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Afrin S; Zhang CRC; Meyer C; Stinson CL; Pham T; Bruxner TJC; Venn NC; Trahair TN; Sutton R; Marschalek R; Lynn Fink J; Moore AS, 2018, 'Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia', Molecular Cancer Research, vol. 16, pp. 279 - 285, http://dx.doi.org/10.1158/1541-7786.MCR-17-0569
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Sutton R; Venn NC; Law T; Boer JM; Trahair TN; Ng A; Den Boer ML; Dissanayake A; Giles JE; Dalzell P; Mayoh C; Barbaric D; Revesz T; Alvaro F; Pieters R; Haber M; Norris MD; Schrappe M; Dalla Pozza L; Marshall GM, 2018, 'A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children', British Journal of Haematology, vol. 180, pp. 550 - 562, http://dx.doi.org/10.1111/bjh.15056
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, vol. 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Vetsch J; Wakefield CE; Robertson EG; Trahair TN; Mateos MK; Grootenhuis M; Marshall GM; Cohn RJ; Fardell JE, 2018, 'Health-related quality of life of survivors of childhood acute lymphoblastic leukemia: a systematic review', Quality of Life Research, vol. 27, pp. 1431 - 1443, http://dx.doi.org/10.1007/s11136-018-1788-5
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Berry N; Scott RJ; Sutton R; Trahair TN; Rowlings P; Enjeti AK, 2018, '16. Australian AIEOP-BFM 2009 acute lymphoblastic leukaemia high-risk findings – Enrichment of IKZF1 deletions and other curious findings', Cancer Genetics, vol. 226-227, pp. 41 - 42, http://dx.doi.org/10.1016/j.cancergen.2018.04.077
    Journal articles | 2018
    Dr Toby Nicholas Trahair
    Balzer BWR; Loo C; Lewis CR; Trahair TN; Anazodo AC, 2018, 'Adenocarcinoma of the Lung in Childhood and Adolescence: A Systematic Review', Journal of Thoracic Oncology, http://dx.doi.org/10.1016/j.jtho.2018.08.2020
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Ladenstein R; Pötschger U; Pearson ADJ; Brock P; Luksch R; Castel V; Yaniv I; Papadakis V; Laureys G; Malis J; Balwierz W; Ruud E; Kogner P; Schroeder H; de Lacerda AF; Beck-Popovic M; Bician P; Garami M; Trahair T; Canete A; Ambros PF; Holmes K; Gaze M; Schreier G; Garaventa A; Vassal G; Michon J; Valteau-Couanet D, 2017, 'Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial', The Lancet Oncology, vol. 18, pp. 500 - 514, http://dx.doi.org/10.1016/S1470-2045(17)30070-0
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Norman M; David C; Wainstein B; Ziegler JB; Cohn R; Mitchell R; O'Brien T; Russell S; Trahair T; Trickett A; Frith K; Gray P, 2017, 'Haematopoietic stem cell transplantation for primary immunodeficiency syndromes: A 5-year single-centre experience', Journal of Paediatrics and Child Health, vol. 53, pp. 988 - 994, http://dx.doi.org/10.1111/jpc.13643
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Trahair T; Sorrentino S; Russell SJ; Sampaio H; Selek L; Plantaz D; Freycon C; Simon T; Kraal K; Beck-Popovic M; Haupt R; Ash S; De Bernardi B, 2017, 'Spinal Canal Involvement in Neuroblastoma', Journal of Pediatrics, vol. 188, pp. 294 - 298, http://dx.doi.org/10.1016/j.jpeds.2017.05.051
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Fardell JE; Vetsch J; Trahair T; Mateos MK; Grootenhuis MA; Touyz LM; Marshall GM; Wakefield CE, 2017, 'Health-related quality of life of children on treatment for acute lymphoblastic leukemia: A systematic review', Pediatric Blood and Cancer, vol. 64, http://dx.doi.org/10.1002/pbc.26489
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Berry N; Scott R; Sutton R; Trahair T; Rowlings P; Enjeti A, 2017, 'HD-SNP Microarray Analysis of the Study 9 High Risk ALL Patients—Increased Yield of Important Prognostic Information', Cancer Genetics, vol. 214-215, pp. 42 - 43, http://dx.doi.org/10.1016/j.cancergen.2017.04.034
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Shadur B; Trahair TN; O'Brien T; Russell SJ; Ziegler JB, 2017, 'Desensitisation to liposomal amphotericin B', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, vol. 5, pp. 181 - 183, http://dx.doi.org/10.1016/j.jaip.2016.08.006
    Journal articles | 2017
    Dr Toby Nicholas Trahair
    Ng M; Forsyth V; Trahair T; Carrington N; Anazodo A, 2017, 'Adolescents, young adults and cancer: What GPs need to know.', Medicine Today, vol. 18(8):, pp. 14 - 22, https://medicinetoday.com.au/2017/august/feature-article/adolescents-young-adults-and-cancer-what-gps-need-know
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Ladenstein R; Poetschger U; Gray J; Valteau-Couanet D; Luksch R; Castel V; Yaniv I; Laureys G; Elliott M; Michon JM; Owens C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck Popovic M; Glogova E; Schreier G; Loibner H; Lode HN, 2016, 'Toxicity and outcome of anti-GD2 antibody ch14.18/CHO in front-line, high-risk patients with neuroblastoma: Final results of the phase III immunotherapy randomisation (HR-NBL1/SIOPEN trial).', Journal of Clinical Oncology, vol. 34, pp. 10500 - 10500, http://dx.doi.org/10.1200/jco.2016.34.15_suppl.10500
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Chang W; Brohl AS; Patidar R; Sindiri S; Shern JF; Wei JS; Song YK; Yohe ME; Gryder B; Zhang S; Calzone KA; Shivaprasad N; Wen X; Badgett TC; Miettinen M; Hartman KR; League-Pascual JC; Trahair TN; Widemann BC; Merchant MS; Kaplan RN; Lin JC; Khan J, 2016, 'Multidimensional clinomics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: A report from the center for cancer research', Clinical Cancer Research, vol. 22, pp. 3810 - 3820, http://dx.doi.org/10.1158/1078-0432.CCR-15-2717
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, vol. 374, pp. 315 - 323, http://dx.doi.org/10.1016/j.canlet.2016.02.021
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Trahair TN; Lock RB; Sutton R; Sia KCS; Evans K; Richmond J; Law T; Venn NC; Irving JA; Moore S; Nievergall E; Dang P; Heatley SL; White DL; Revesz T, 2016, 'Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL', Bone Marrow Transplantation, vol. 51, pp. 1279 - 1282, http://dx.doi.org/10.1038/bmt.2016.122
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Ladenstein R; Poetschger U; Elliott M; Luksch R; Castel V; Yaniv I; Papadakis V; Laureys G; Malis J; Balwierz W; Ruud E; Kogner P; Schroeder H; Forjaz De Lacerda A; Beck Popovic M; Bician P; Garami M; Trahair T; Pearson ADJ; Valteau Couanet D, 2016, 'Prognostic factors in stage 4 neuroblastoma treated with busulphan-melphalan: Report from the European HR-NBL1/Siopen trial.', Journal of Clinical Oncology, vol. 34, pp. 10527 - 10527, http://dx.doi.org/10.1200/jco.2016.34.15_suppl.10527
    Journal articles | 2016
    Dr Toby Nicholas Trahair
    Fischer M; Wulff B; Baruchel S; Berlanga P; Trahair T; Mechinaud F; Schulte J; Modak S; Merks JH; Zwaan CM; Marshall LV; Casanova M; Branle F; Malet I; Emeremni AC; Geoerger B, 2016, 'Phase 1 study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK): Safety, pharmacokinetics and efficacy results from the fed population', European Journal of Cancer, vol. 69, pp. S49 - S50, http://dx.doi.org/10.1016/s0959-8049(16)32732-0
    Journal articles | 2015
    Dr Toby Nicholas Trahair
    Geoerger B; Schulte J; Zwaan CM; Casanova M; Fischer M; Moreno L; Trahair T; Jimenez I; Kang HJ; Pappo AS; Schafer E; Weiss BD; Healy ME; Li K; Lin T; Boral A; Pearson ADJ, 2015, 'Phase I study of ceritinib in pediatric patients (Pts) with malignancies harboring a genetic alteration in ALK (ALK+): Safety, pharmacokinetic (PK), and efficacy results.', Journal of Clinical Oncology, vol. 33, pp. 10005 - 10005, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.10005
    Journal articles | 2015
    Dr Toby Nicholas Trahair
    Sutton R; Shaw PJ; Venn NC; Law T; Dissanayake A; Kilo T; Haber M; Norris MD; Fraser C; Alvaro F; Revesz T; Trahair TN; Dalla-Pozza L; Marshall GM; O'Brien TA, 2015, 'Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia', British Journal of Haematology, vol. 168, pp. 395 - 404, http://dx.doi.org/10.1111/bjh.13142
    Journal articles | 2015
    Dr Toby Nicholas Trahair
    Bartlett A; Goeman E; Vedi A; Mostaghim M; Trahair T; O’Brien TA; Palasanthiran P; McMullan B, 2015, 'A pilot study of a computerized decision support system to detect invasive fungal infection in pediatric hematology/oncology patients', Infection Control and Hospital Epidemiology, vol. 36, pp. 1313 - 1317, http://dx.doi.org/10.1017/ice.2015.179
    Journal articles | 2015
    Dr Toby Nicholas Trahair
    Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JWH; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T, 2015, 'WDR5 supports an N-myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma', Cancer Research, vol. 75, pp. 5143 - 5154, http://dx.doi.org/10.1158/0008-5472.CAN-15-0423
    Journal articles | 2014
    Dr Toby Nicholas Trahair
    Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, vol. 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032
    Journal articles | 2013
    Dr Toby Nicholas Trahair
    Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, vol. 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205
    Journal articles | 2013
    Dr Toby Nicholas Trahair
    Sekyere E; Thomas WD; Keating J; Calao M; Cui HJ; Chen JB; Raif A; Jankowski K; Cheung B; Davies NP NP; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation', Oncogene, vol. 32, pp. 3616 - 3626, http://dx.doi.org/10.1038/onc.2012.368
    Journal articles | 2013
    Dr Toby Nicholas Trahair
    Malyukova A; Papa R; O'Brien R; Giles JE; Trahair TN; Pozza LD; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Marshall GM; Giles J, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, vol. 27, pp. 1053 - 1062, http://dx.doi.org/10.1038/leu.2012.361
    Journal articles | 2013
    Dr Toby Nicholas Trahair
    Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, vol. 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559
    Journal articles | 2013
    Dr Toby Nicholas Trahair
    Pasquier E; Trahair T; Kavallaris M; Andre N, 2013, 'Reply: Comment on 'beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'-β- blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs', British Journal of Cancer, vol. 109, pp. 2024 - 2025, http://dx.doi.org/10.1038/bjc.2013.498
    Journal articles | 2012
    Dr Toby Nicholas Trahair
    Bhadri V; Trahair TN; Lock RB; bhadri , 2012, 'Glucocorticoid resistance in paediatric acute lymphoblastic leukaemia', Journal of Paediatrics and Child Health, vol. 48, pp. 634 - 640, http://dx.doi.org/10.1111/j.1440-1754.2011.02212.x
    Journal articles | 2012
    Dr Toby Nicholas Trahair
    Elahi MM; Houng C; Trahair T; Ravindranathan H; Grant PW, 2012, 'Extracorporeal Membrane Oxygenation Support in a Situation of Diagnostic Dilemma', Heart Lung and Circulation, vol. 21, pp. 821 - 823, http://dx.doi.org/10.1016/j.hlc.2012.04.014
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Ladenstein RL; Poetschger U; Luksch R; Brock P; Castel V; Yaniv I; Papadakis V; Laureys G; Malis J; Balwierz W; Ruud E; Kogner P; Schroeder H; Forjaz De Lacerda A; Beck Popovic M; Bician P; Garami M; Trahair T; Pearson AD; Valteau Couanet D, 2011, 'Busulphan-melphalan as a myeloablative therapy (MAT) for high-risk neuroblastoma: Results from the HR-NBL1/SIOPEN trial.', Journal of Clinical Oncology, vol. 29, pp. 2 - 2, http://dx.doi.org/10.1200/jco.2011.29.18_suppl.2
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Ladenstein RL; Poetschger U; Luksch R; Brock P; Castel V; Yaniv I; Papadakis V; Laureys G; Malis J; Balwierz W; Ruud E; Kogner P; Schroeder H; Forjaz De Lacerda A; Beck Popovic M; Bician P; Garami M; Trahair T; Pearson AD; Valteau Couanet D, 2011, 'Busulphan-melphalan as a myeloablative therapy (MAT) for high-risk neuroblastoma: Results from the HR-NBL1/SIOPEN trial.', Journal of Clinical Oncology, vol. 29, pp. 2 - 2, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.2
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, vol. 7, pp. e1 - e14, http://dx.doi.org/10.1371/journal.pgen.1002135
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Bhadri V; Cowley MJ; Kaplan W; Trahair TN; Lock RB, 2011, 'Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia', BMC Genomics, vol. 12, pp. 1 - 13, http://dx.doi.org/10.1186/1471-2164-12-565
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Bhadri VA; Satharasinghe K; Sugo E; Barbaric D; Trahair TN, 2011, 'Excellent response to dasatinib of childhood Philadelphia positive intracranial acute lymphoblastic leukaemia tumours', British Journal of Haematology, vol. 152, pp. 347 - 349, http://dx.doi.org/10.1111/j.1365-2141.2010.08465.x
    Journal articles | 2011
    Dr Toby Nicholas Trahair
    Marsh DJ; Trahair TN; Kirk EP, 2011, 'Mutant AKT1 in Proteus Syndrome', New England Journal of Medicine, vol. 365, pp. 2141 - 2142, http://dx.doi.org/10.1056/NEJMc1111367
    Journal articles | 2010
    Dr Toby Nicholas Trahair
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, vol. 29, pp. 5957 - 5968, http://dx.doi.org/10.1038/onc.2010.332
    Journal articles | 2009
    Dr Toby Nicholas Trahair
    Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, vol. 27, http://dx.doi.org/10.1200/JCO.2009.24.0036
    Journal articles | 2008
    Dr Toby Nicholas Trahair
    Marsh DJ; Trahair TN; Martin J; Chee W; Walker JL; Kirk EP; Baxter RC; Marshall GM, 2008, 'Rapamycin treatment for a child with germline PTEN mutation', Nature Clinical Practice Oncology, vol. 5, pp. 357 - 361, http://dx.doi.org/10.1038/ncponc1112
    Journal articles | 2008
    Dr Toby Nicholas Trahair
    Trahair TN; Wainstein B; Manton N; Bourne A; Ziegler JB; Rice M; Russell SJ, 2008, 'Rituximab for lymphoproliferative disease prior to haematopoietic stem cell transplantation for X-linked severe combined immunodeficiency', Pediatric Blood and Cancer, vol. 50, pp. 366 - 369, http://dx.doi.org/10.1002/pbc.20887
    Journal articles | 2007
    Dr Toby Nicholas Trahair
    Trahair TN; Vowels MR; Johnston K; Cohn RJ; Russell SJ; Neville KA; Carroll S; Marshall GM, 2007, 'Long-term outcomes in children with high-risk neuroblastoma treated with autologous stem cell transplantation', Bone Marrow Transplantation, vol. 40, pp. 741 - 746, http://dx.doi.org/10.1038/sj.bmt.1705809
    Journal articles | 2007
    Dr Toby Nicholas Trahair
    Trahair TN; Andrews L; Cohn RJ, 2007, 'Recognition of Li Fraumeni syndrome at diagnosis of a locally advance extremity rhabdomyosarcoma', Pediatric Blood and Cancer, vol. 48, pp. 345 - 348, http://dx.doi.org/10.1002/pbc.20795
    Journal articles | 2005
    Dr Toby Nicholas Trahair
    Ziegler DS; Russell SJ; Rozenberg G; James CA; Trahair TN; O'Brien TA, 2005, 'Goats' milk quackery', Journal of Paediatrics and Child Health, vol. 41, pp. 569 - 571, http://dx.doi.org/10.1111/j.1440-1754.2005.00723.x
    Journal articles | 2004
    Dr Toby Nicholas Trahair
    Trahair T; Cohn R; Russell S; Marshall GM; Pokorny CS, 2004, 'Investigation of the child with easy bruising', Medicine Today, vol. 5, pp. 61 - 69
    Journal articles | 2001
    Dr Toby Nicholas Trahair
    Fleming J; Ginn SL; Weinberger RP; Trahair TN; Smythe JA; Alexander IE, 2001, 'Adeno-associated virus and lentivirus vectors mediate efficient and sustained transduction of cultured mouse and human dorsal root ganglia sensory neurons', Human Gene Therapy, vol. 12, pp. 77 - 86, http://dx.doi.org/10.1089/104303401450997
    Journal articles | 2000
    Dr Toby Nicholas Trahair
    Trahair TN; Alexander IE; Rowe PB; Smythe JA, 2000, 'The adenovirus E4 ORF6 and E1b 55 kDa proteins cooperate in a p53-independent manner to enhance transduction by recombinant adeno-associated virus vectors', Journal of General Virology, vol. 81, pp. 2983 - 2991, http://dx.doi.org/10.1099/0022-1317-81-12-2983
    Journal articles | 1996
    Dr Toby Nicholas Trahair
    Dos Remedios CG; Berry DA; Carter LK; Coumans JV; Heinke MY; Kiessling PC; Seeto RK; Thorvaldson T; Trahair T; Yeoh T; Gunning PW; Hardeman E; Humphery-Smith I; Naidoo D; Keogh A, 1996, 'Different electrophoretic techniques produce conflicting data in the analysis of myocardial samples from dilated cardiomyopathy patients: protein levels do not necessarily reflect mRNA levels', Electrophoresis, vol. 17, pp. 235 - 238, http://dx.doi.org/10.1002/elps.1150170140
    Journal articles | 1993
    Dr Toby Nicholas Trahair
    Trahair T; Yeoh T; Cartmill T; Keogh A; Spratt P; Chang V; dos Remedios CG; Gunning P, 1993, 'Myosin Light Chain Gene Expression Associated with Disease States of the Human Heart', Journal of Molecular and Cellular Cardiology, vol. 25, pp. 577 - 585, http://dx.doi.org/10.1006/jmcc.1993.1067
  • Conference Papers | 2021
    Dr Toby Nicholas Trahair
    Vijayasubhash V, 2021, 'Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR', in Analysis of DNA minimal residual disease markers in pediatric solid cancers using quantitative real time PCR and droplet digital PCR, presented at AACR 2021, http://dx.doi.org/10.1158/1538-7445.AM2021-639
    Conference Abstracts | 2020
    Dr Toby Nicholas Trahair
    Dong-Anh K-Q; Nagabushan S; Manoharan N; Arndt G; Barahona P; Cowley MJ; Ekert PG; Failes T; Bolanos NF; Gauthier M; Gifford AJ; Haber M; Kumar A; Lock RB; Marshall GM; Mayoh C; Mould E; Norris MD; Gopalakrishnan A; Omer N; Trebilcock P; Trahair TN; Tsoli M; Tucker K; Wong M; Tyrrell V; Lau L; Ziegler DS, 2020, 'PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 302 - 302, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100118&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Dr Toby Nicholas Trahair
    Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-SY09-02
    Conference Abstracts | 2020
    Dr Toby Nicholas Trahair
    Atkinson C; Tactacan C; Kamili A; Saletta F; Gana C; Eden G; Mayoh C; Lock R; Norris M; Haber M; Gifford A; Trahair T; Fletcher J, 2020, 'Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a35
    Conference Abstracts | 2020
    Dr Toby Nicholas Trahair
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a52
    Conference Papers | 2020
    Dr Toby Nicholas Trahair
    Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O’Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Quang DAK; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Bolanos NF; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O’Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2020, 'Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in Oral Presentations - Invited Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-ia13
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Lin B; Kennedy B; McBride J; Dalla-Pozza L; Trahair T; McCowage G; Coward E; Plush L; Robinson PD; Hardaker K; Widger J; Ng A; Jaffe A; Selvadurai H, 2019, 'Long-term morbidity of respiratory viral infections during chemotherapy in children with leukaemia', in Pediatric Pulmonology, WILEY, Vol. 54, pp. 1821 - 1829, http://dx.doi.org/10.1002/ppul.24456
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Chen J; Nelson C; Liu P; Tee AE; Atmadibrata B; MacKenzie K; Fletcher J; Trahair T; Polly P; Reddel R; Pickett H; Liu T, 2019, 'Efficacious targeting of TERT oncogene rearrangement with BET bromodomain inhibitor and proteasome inhibitor combination therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-5209
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Chen J; Nelson C; Liu P; Tee AE; Atmadibrata B; MacKenzie K; Fletcher J; Trahair T; Polly P; Reddel R; Pickett H; Liu T, 2019, 'Abstract 5209: Efficacious targeting of TERT oncogene rearrangement with BET bromodomain inhibitor and proteasome inhibitor combination therapy', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-5209
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Abstract 2884: Establishment of patient-derived xenograft models for high-risk neuroblastoma', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2884
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Fordham AM; Blackburn J; Heyer EE; Xie J; Mould EV; Gifford AJ; Morgan LT; Wadham C; Fadia M; Fletcher JI; MacKenzie KL; Trahair TN, 2019, 'Abstract 4824: Targeting CD30 as a novel treatment strategy inRANBP2-ALK-rearranged inflammatory myofibroblastic tumor', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-4824
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3111
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Abstract 4741: Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.am2019-4741
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O’Brien T; Quang DAK; Cowley M; Ekert P; Ziegler DS, 2019, 'THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii118 - ii118, http://dx.doi.org/10.1093/neuonc/noz036.228
    Conference Papers | 2019
    Dr Toby Nicholas Trahair
    Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Abstract 3111: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in Clinical Research (Excluding Clinical Trials), American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3111
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Atkinson C; Tactacan CM; Kamili A; Saletta F; Gana C; Eden GL; Mayoh C; Lock RB; Norris MD; Haber M; Gifford AJ; Trahair TN; Fletcher JI, 2019, 'Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-4741
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Kamili A; Gifford AJ; Li N; Mayoh C; Eden GL; Xie J; Lukeis RE; Norris MD; Haber M; McCowage G; Trahair TN; Fletcher JI, 2019, 'Establishment of patient-derived xenograft models for high-risk neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2884
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Fordham AM; Blackburn J; Heyer EE; Xie J; Mould EV; Gifford AJ; Morgan LT; Wadham C; Fadia M; Fletcher JI; MacKenzie KL; Trahair TN, 2019, 'Targeting CD30 as a novel treatment strategy in RANBP2-ALK-rearranged inflammatory myofibroblastic tumor', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-4824
    Conference Abstracts | 2019
    Dr Toby Nicholas Trahair
    Michels N; Boer JM; Lopez-Yurda M; De Groot-Kruseman HA; van der Velden V; Moorman AV; Enshaei A; Vora A; Sutton R; Trahair T; Dalla-Pozza L; Pieters R; Zwaan MC; Den Boer ML, 2019, 'Minimal Residual Disease and IKZF1 As Predictors of Relapse, and Increased Treatment Related Mortality in Down Syndrome Acute Lymphoblastic Leukemia: A Unique and Large International Matched Case-Control Study', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, Vol. 134, presented at 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, 07 December 2019 - 10 December 2019, http://dx.doi.org/10.1182/blood-2019-124290
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Tyrrell V; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Mould E; O'Brien T; Pinese M; Khuong-Quang DA; Thomas D; Trahair T; Tsoli M; Tucker K; Wharby M; Wong M; Xie J; Ziegler D, 2018, 'Zero childhood cancer – Accelerating translation of experimental oncology: Better matching drug to target', in Pathology, Elsevier BV, Vol. 50, pp. S31 - S31, http://dx.doi.org/10.1016/j.pathol.2017.12.072
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo A; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien TA, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective.', in PSYCHO-ONCOLOGY, WILEY, Hong Kong, Vol. 27, pp. 56 - 57, presented at International Psycho-Oncology Society, Hong Kong, 31 October 2018 - 02 November 2018, http://dx.doi.org/10.1111/jpc.14248
    Conference Papers | 2018
    Dr Toby Nicholas Trahair
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo AC; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien T, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster)', in Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster), Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, presented at Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, 14 June 2018 - 16 June 2018
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin J; Gayevski V; Kumar A; Kaplan W; Ekert P; Franshaw L; Gifford A; Weber M; Rodriguez M; Mayoh C; Cohn R; Arndt G; Lock R; Tyrrell V; Norris M; Haber M; Lau L; Dong AKQ; Wong M; Trahair T; Marshall GM; Cowley MJ; Ziegler DS, 2018, 'Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-137
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Mould E; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Norris M; O'Brien T; Pinese M; Dong AKQ; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler D; Tyrrell V, 2018, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-138
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Xie JA; Mould EVA; Fordham A; Gifford AJ; Trahair T; Mackenzie KL, 2018, 'Abstract A19: Establishment of in vitro and in vivo models of inflammatory myofibroblastic tumor', in Omics, American Association for Cancer Research, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-a19
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Afrin S; Zhang CRC; Meyer C; Maybury M; Pham T; Venn N; Trahair TN; Sutton R; Marschalek R; Fink L; Moore AS, 2018, 'Quantitative Analysis of MLL Fusion Transcripts By Droplet Digital PCR to Monitor Minimal Residual Disease in MLL-Rearranged Acute Myeloid Leukemia', in BLOOD, AMER SOC HEMATOLOGY, San Diego, CA, Vol. 132, presented at 60th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA, 01 December 2018 - 04 December 2018, http://dx.doi.org/10.1182/blood-2018-99-117761
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Wakefield CE; Vetsch J; Tucker KM; Warby M; O'Brien T; Techakesari P; Glenn M; Trahair TN; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'Families' and Healthcare Professionals' Hopes and Expectations Participating in a Precision Medicine Trial for Children with High-Risk Cancer: The PRISM-Impact Study', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S62 - S62, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000445195000120&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Toby Nicholas Trahair
    Vetsch J; Wakefield CE; Tucker K; Warby M; Techakesari P; Marshall G; Trahair TN; O'Brien T; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'The PRISM-IMPACT study: What are the hopes and expectations of families and health care professionals enrolling in a personalised medicine trial for high risk childhood cancers?', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, Milan, ITALY, Vol. 27, pp. 690 - 691, presented at 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, ITALY, 16 June 2018 - 19 June 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313105140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Dr Toby Nicholas Trahair
    Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
    Conference Posters | 2017
    Dr Toby Nicholas Trahair
    Shadur B; Trahair TN; O'Brien T; Russell SJ; Ziegler JB, 2017, 'Desensitisation to liposomal amphotericin B', Vol. 5, pp. 181 - 183, http://dx.doi.org/10.1016/j.jaip.2016.08.006
    Conference Abstracts | 2017
    Dr Toby Nicholas Trahair
    Mateos MK; Trahair TN; Mayoh C; Barbaro PM; George C; Sutton R; Revesz T; Barbaric D; Giles J; Alvaro F; Mechinaud FM; Catchpoole DR; Kotecha RS; Quinn MCJ; Chenevix-Trench G; MacGregor S; Dalla-Pozza L; Marshall GM, 2017, 'Clinical and Germline Risk Factors for the Occurrence of Multiple Treatment Toxicities during Childhood Acute Lymphoblastic Leukemia (ALL) Therapy', in BLOOD, AMER SOC HEMATOLOGY, Atlanta, GA, Vol. 130, presented at 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA, 09 December 2017 - 12 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432419405157&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Dr Toby Nicholas Trahair
    Mateos MK; Trahair TN; Mayoh C; Barbaro PM; Sutton R; Revesz T; Barbaric D; Giles J; Alvaro F; Mechinaud F; Catchpoole D; Kotecha RS; Dalla-Pozza L; Marshall GM, 2016, 'Clinical Predictors of Venous Thromboembolism during Therapy for Childhood Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, San Diego, CA, Vol. 128, presented at 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA, 03 December 2016 - 06 December 2016, http://dx.doi.org/10.1182/blood.V128.22.1182.1182
    Conference Papers | 2016
    Dr Toby Nicholas Trahair
    Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2016, 'Abstract 51: Molecular profiling of relapsed childhood cancer', in Other Topics, American Association for Cancer Research, presented at Abstracts: AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy; June 13-16, 2015; Salt Lake City, UT, http://dx.doi.org/10.1158/1557-3265.pmsclingen15-51
    Conference Abstracts | 2016
    Dr Toby Nicholas Trahair
    Afrin S; Meyer C; Stinson CL; Thy P; Bruxner TJC; Venn NC; Trahair TN; Sutton R; Marschalek R; Fink L; Moore AS, 2016, 'Identification of Multiple, Patient-Specific MLL Fusion Transcript Isoforms in Childhood Leukemia Using Anchored Multiplex PCR-Based Enrichment (AMP-E)', in BLOOD, AMER SOC HEMATOLOGY, San Diego, CA, Vol. 128, presented at 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA, 03 December 2016 - 06 December 2016, http://dx.doi.org/10.1182/blood.V128.22.2908.2908
    Conference Papers | 2015
    Dr Toby Nicholas Trahair
    Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Dr Toby Nicholas Trahair
    Sartor M; Barbaric D; Law T; Dissanayake A; Venn NC; Karsa M; Wong SWJ; Norris MD; Revesz T; Ritchie P; Shaw PJ; Bradstock KF; Pozza LD; Trahair TN; Sutton R, 2015, 'Improved Concordance of Minimal Residual Disease Measurements By Quantitative PCR and 10-Color Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, Vol. 126, presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2015
    Dr Toby Nicholas Trahair
    White V; Anazodo AC; Bibby H; Orme L; Conyers R; Nicholls W; Pinkerton R; Harrup R; Osborn M; Philips M; Trahair T; Thompson K; Green M; Coory M, 2015, 'Management of Bone Cancers in Australian Adolescents and Young Adults (AYAs).', presented at Clinical Oncology Society of Australia’s Annual Scientific meeting, Hobart, Australia., Hobart Australia, 17 November 2015 - 19 November 2015
    Conference Presentations | 2014
    Dr Toby Nicholas Trahair
    Kim PY; Tan O; Trahair T; Liu T; Marshall GM; Cheung BB, 2014, 'TRIM16 inhibits cell growth through direct interaction and modulation of TDP43 protein stability in cancer cells', Vol. 74, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-1403
    Conference Papers | 2011
    Dr Toby Nicholas Trahair
    Namasivayam M; Zaunders J; Ip S; Scott GM; Shaw P; Trahair TN; O''brien T; Rawlinson WD; Walls T; Kelleher AD; Ziegler JB, 2011, 'Performance of quantiferon-cmv (r) and whole-blood cd4(+)cd25(+)cd134(+) assays in identification of human cytomegalovirus-specific t-cells in children post-haematopoietic stem cell transplantation', in Internal Medicine Journal, Blackwell Publishing Asia, pp. 12 - 12, http://dx.doi.org/10.1111/%28ISSN%291445-5994
    Conference Papers | 2010
    Dr Toby Nicholas Trahair
    Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair T; Scarlett C; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Stossi F; Katzenellenbogen BS; Biankin AV; Perini G; Liu T, 2010, 'Abstract 4869: Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', in Cellular and Molecular Biology, American Association for Cancer Research, presented at Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am10-4869
    Conference Papers | 1992
    Dr Toby Nicholas Trahair
    DOSREMEDIOS CG; TRAHAIR T; YEOH T; CHANG V; CARTMILL T; GUNNING P, 1992, 'A MYOSIN LIGHT CHAIN-LIKE PROTEIN ASSOCIATED WITH END-STAGE HEART-FAILURE', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, pp. R8 - R8, http://dx.doi.org/10.1016/0022-2828(92)91073-E

Awards

Grants

Grants & Fellowship Support

  • 2005       National Health and Medical Research Council Australian Biomedical (Peter Doherty) Training Fellowship, “Ex vivo expansion of human umbilical cord blood stem and progenitor cells”, Amount awarded $264,000
  • 2007       Sylvia and Charles Viertel Charitable Foundation Clinical Investigatorship, “Differentiation trapping to identify mutations in cellular genes which contribute to the development of the children’s cancer neuroblastoma”. Amount awarded $60,000
  • 2007       Clive and Vera Ramciotti Foundation Establishment Gift, “Identification of mutations in cellular genes which contribute to the development of neuroblastoma using retroviral gene trap mutagenesis in mouse embryonic stem cells”. Amount awarded $30,000
  • 2007       Cancer Institute NSW Clinical Research Fellowship, “Gene trapping to identify mutations in cellular genes which contribute to the development of embryonal cancers in children”. Amount awarded $323,289
  • 2007       Sydney Children’s Hospital Foundation Grant, “Gene trap mutagenesis to identify mutations in cellular genes which contribute to the development of acute lymphoblastic leukaemia”. Amount awarded $50,000
  • 2012       Kids Cancer Alliance. Project Grant “Predictive clinical and genetic risk factors for the side-effects of chemotherapy in children treated for acute lymphoblastic leukaermia”. Amount awarded $380,000. Role: Chief Investigator A
  • 2014       Kids Cancer Alliance. Project Grant “Establishment of patient-derived xenograft (PDX) models for high risk neuroblastoma” Amount Awarded: $300,000. Role Chief Investigator B
  • 2016       National Health & Medical Research Council Project Grant APP1102172A Phase I Study of PiggyBac CD19 Specific Chimeric Antigen Receptor T-cells for Therapy of Persistent and Relapsed B-cell Leukaemia and Lymphoma Post Allogeneic Stem Cell Transplantation (The CARTELL Study)”. Amount awarded: $357,589.80. Role Chief Investigator F.

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