Dr Tristan Reekie

Dr Tristan Reekie

Senior Lecturer

PhD ANU 2013

B. Sci (Hons) ANU 2007

LLB ANU 2010

UNSW Canberra
School of Science

I completed my PhD in 2013 at ANU and then completed a postdoctoral position at ETH Zurich before returning to Australia to work  at the University of Sydney. I began my independent career at ANU in 2019, which I have now continued at the University of New South Wales Canberra.

My research is focused on small molecule organic chemistry with application to materials, plant science and medicinal chemistry.

In addition to my research, I am also heavily involved in teaching and outreach to enhance interest in science amongst students and the general public. I have long-term involvement with programs such as the Australian Chemistry Olympiad to encourage the next generation of scientist.

Phone
+61-2-5114 5067
Location
Room 214 Building 22
  • Books | 2022
    Werry EL; Reekie TA; Kassiou M, 2022, Preface
    Books | 2022
    2022, Oxytocin, Werry EL; Reekie TA; Kassiou M, (eds.), Springer US, http://dx.doi.org/10.1007/978-1-0716-1759-5
  • Book Chapters | 2023
    Reekie TA; Kassiou M, 2023, 'Synthetic cannabinoid receptor agonists: An overview', in Neurobiology and Physiology of the Endocannabinoid System, pp. 493 - 504, http://dx.doi.org/10.1016/B978-0-323-90877-1.00038-3
    Book Chapters | 2022
    Nashar PE; Whitfield AA; Mikusek J; Reekie TA, 2022, 'The Current Status of Drug Discovery for the Oxytocin Receptor', in Methods in Molecular Biology, pp. 153 - 174, http://dx.doi.org/10.1007/978-1-0716-1759-5_10
  • Journal articles | 2024
    Stewart CD; White NG; Barrow RA; Reekie TA, 2024, 'Synthesis and spectroscopic investigation of substituted piperazine-2,5-dione derivatives', Tetrahedron, 153, http://dx.doi.org/10.1016/j.tet.2024.133838
    Journal articles | 2023
    Gimła M; Pyrczak-Felczykowska A; Malinowska M; Hać A; Narajczyk M; Bylińska I; Reekie TA; Herman-Antosiewicz A, 2023, 'The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo', Cancer Cell International, 23, http://dx.doi.org/10.1186/s12935-023-03054-x
    Journal articles | 2023
    Gunawan GA; Gimła M; Gardiner MG; Herman-Antosiewicz A; Reekie TA, 2023, 'Divergent reactivity of usnic acid and evaluation of its derivatives for antiproliferative activity against cancer cells', Bioorganic and Medicinal Chemistry, 79, http://dx.doi.org/10.1016/j.bmc.2023.117157
    Journal articles | 2022
    Pyrczak-Felczykowska A; Reekie TA; Jąkalski M; Hać A; Malinowska M; Pawlik A; Ryś K; Guzow-Krzemińska B; Herman-Antosiewicz A, 2022, 'The Isoxazole Derivative of Usnic Acid Induces an ER Stress Response in Breast Cancer Cells that Leads to Paraptosis-like Cell Death', International Journal of Molecular Sciences, 23, pp. 1802, http://dx.doi.org/10.3390/ijms23031802
    Journal articles | 2021
    Chaney AM; Lopez-Picon FR; Serrière S; Wang R; Bochicchio D; Webb SD; Vandesquille M; Harte MK; Georgiadou C; Lawrence C; Busson J; Vercouillie J; Tauber C; Buron F; Routier S; Reekie T; Snellman A; Kassiou M; Rokka J; Davies KE; Rinne JO; Salih DA; Edwards FA; Orton LD; Williams SR; Chalon S; Boutin H, 2021, 'Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: A collaborative multi-modal study', Theranostics, 11, pp. 6644 - 6667, http://dx.doi.org/10.7150/thno.56059
    Journal articles | 2021
    Sheikh Z; Bradbury P; Reekie TA; Pozzoli M; Robinson PD; Kassiou M; Young PM; Ong HX; Traini D, 2021, 'Tobramycin and Colistin display anti-inflammatory properties in CuFi-1 cystic fibrosis cell line', European Journal of Pharmacology, 902, pp. 174098, http://dx.doi.org/10.1016/j.ejphar.2021.174098
    Journal articles | 2020
    Galletta M; Reekie TA; Nagalingam G; Bottomley AL; Harry EJ; Kassiou M; Triccas JA, 2020, 'Rapid antibacterial activity of cannabichromenic acid against methicillin-resistant staphylococcus aureus', Antibiotics, 9, pp. 1 - 11, http://dx.doi.org/10.3390/antibiotics9080523
    Journal articles | 2020
    Gillis A; Gondin AB; Kliewer A; Sanchez J; Lim HD; Alamein C; Manandhar P; Santiago M; Fritzwanker S; Schmiedel F; Katte TA; Reekie T; Grimsey NL; Kassiou M; Kellam B; Krasel C; Halls ML; Connor M; Lane JR; Schulz S; Christie MJ; Canals M, 2020, 'Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists', Science Signaling, 13, http://dx.doi.org/10.1126/scisignal.aaz3140
    Journal articles | 2020
    Green D; Eyre H; Singh A; Taylor JT; Chu J; Jeys L; Sumathi V; Coonar A; Rassl D; Babur M; Forster D; Alzabin S; Ponthan F; McMahon A; Bigger B; Reekie T; Kassiou M; Williams K; Dalmay T; Fraser WD; Finegan KG, 2020, 'Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer', Oncogene, 39, pp. 5553 - 5569, http://dx.doi.org/10.1038/s41388-020-1379-0
    Journal articles | 2020
    Sokias R; Werry EL; Alison Cheng HW; Lloyd JH; Sohler G; Danon JJ; Montgomery AP; Du JJ; Gao Q; Hibbs DE; Ittner LM; Reekie TA; Kassiou M, 2020, 'Tricyclic heterocycles display diverse sensitivity to the A147T TSPO polymorphism', European Journal of Medicinal Chemistry, 207, pp. 112725, http://dx.doi.org/10.1016/j.ejmech.2020.112725
    Journal articles | 2020
    Vo SV; Banister SD; Freelander I; Werry EL; Reekie TA; Ittner LM; Kassiou M, 2020, 'Reversing binding sensitivity to A147T translocator protein', RSC Medicinal Chemistry, 11, pp. 511 - 517, http://dx.doi.org/10.1039/c9md00580c
    Journal articles | 2020
    2020, 'Erratum: Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells (Journal of Natural Products (2019) 82:7 (1768-1778) DOI: 10.1021/acs.jnatprod.8b00980)', , http://dx.doi.org/10.1021/acs.jnatprod.0c00129
    Journal articles | 2019
    Cheng HWA; Sokias R; Werry EL; Ittner LM; Reekie TA; Du J; Gao Q; Hibbs DE; Kassiou M, 2019, 'First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold', Journal of Medicinal Chemistry, 62, pp. 8235 - 8248, http://dx.doi.org/10.1021/acs.jmedchem.9b00980
    Journal articles | 2019
    Danon JJ; Reekie TA; Kassiou M, 2019, 'Challenges and Opportunities in Central Nervous System Drug Discovery', Trends in Chemistry, 1, pp. 612 - 624, http://dx.doi.org/10.1016/j.trechm.2019.04.009
    Journal articles | 2019
    Gulliver D; Werry E; Reekie TA; Katte TA; Jorgensen W; Kassiou M, 2019, 'Targeting the Oxytocin System: New Pharmacotherapeutic Approaches', Trends in Pharmacological Sciences, 40, pp. 22 - 37, http://dx.doi.org/10.1016/j.tips.2018.11.001
    Journal articles | 2019
    Longworth M; Reekie TA; Blakey K; Boyd R; Connor M; Kassiou M, 2019, 'New-generation azaindole-adamantyl-derived synthetic cannabinoids', Forensic Toxicology, 37, pp. 350 - 365, http://dx.doi.org/10.1007/s11419-019-00466-1
    Journal articles | 2019
    Moir M; Danon JJ; Reekie TA; Kassiou M, 2019, 'An overview of late-stage functionalization in today’s drug discovery', Expert Opinion on Drug Discovery, 14, pp. 1137 - 1149, http://dx.doi.org/10.1080/17460441.2019.1653850
    Journal articles | 2019
    Pyrczak-Felczykowska A; Narlawar R; Pawlik A; Guzow-Krzemińska B; Artymiuk D; Hać A; Ryś K; Rendina LM; Reekie TA; Herman-Antosiewicz A; Kassiou M, 2019, 'Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells', Journal of Natural Products, 82, pp. 1768 - 1778, http://dx.doi.org/10.1021/acs.jnatprod.8b00980
    Journal articles | 2019
    Reekie TA; Williams CM; Rendina LM; Kassiou M, 2019, 'Cubanes in Medicinal Chemistry', Journal of Medicinal Chemistry, 62, pp. 1078 - 1095, http://dx.doi.org/10.1021/acs.jmedchem.8b00888
    Journal articles | 2018
    Callis TB; Reekie TA; O'Brien-Brown J; Wong ECN; Werry EL; Elias N; Jorgensen WT; Tsanaktsidis J; Rendina LM; Kassiou M, 2018, 'The role of polycyclic frameworks in modulating P2X7 receptor function', Tetrahedron, 74, pp. 1207 - 1219, http://dx.doi.org/10.1016/j.tet.2017.10.075
    Journal articles | 2018
    Coughlin JM; Yang T; Rebman AW; Bechtold KT; Du Y; Mathews WB; Lesniak WG; Mihm EA; Frey SM; Marshall ES; Rosenthal HB; Reekie TA; Kassiou M; Dannals RF; Soloski MJ; Aucott JN; Pomper MG, 2018, 'Imaging glial activation in patients with post-treatment Lyme disease symptoms: A pilot study using [ 11 C]DPA-713 PET', Journal of Neuroinflammation, 15, pp. 346, http://dx.doi.org/10.1186/s12974-018-1381-4
    Journal articles | 2018
    Hagens MHJ; Golla SV; Wijburg MT; Yaqub M; Heijtel D; Steenwijk MD; Schober P; Brevé JJP; Schuit RC; Reekie TA; Kassiou M; Van Dam AM; Windhorst AD; Killestein J; Barkhof F; Van Berckel BNM; Lammertsma AA, 2018, 'In vivo assessment of neuroinflammation in progressive multiple sclerosis: A proof of concept study with [18F]DPA714 PET', Journal of Neuroinflammation, 15, pp. 314, http://dx.doi.org/10.1186/s12974-018-1352-9
    Journal articles | 2018
    Reekie TA; Scott MP; Kassiou M, 2018, 'The evolving science of phytocannabinoids', Nature Reviews Chemistry, 2, pp. 0101, http://dx.doi.org/10.1038/S41570-017-0101
    Journal articles | 2018
    Ryan P; Patel B; Makwana V; Jadhav HR; Kiefel M; Davey A; Reekie TA; Rudrawar S; Kassiou M, 2018, 'Peptides, Peptidomimetics, and Carbohydrate-Peptide Conjugates as Amyloidogenic Aggregation Inhibitors for Alzheimer's Disease', ACS Chemical Neuroscience, 9, pp. 1530 - 1551, http://dx.doi.org/10.1021/acschemneuro.8b00185
    Journal articles | 2018
    Zhou Q; Reekie TA; Abbassi RH; Indurthi Venkata D; Font JS; Ryan RM; Munoz L; Kassiou M, 2018, 'Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A', Bioorganic and Medicinal Chemistry, 26, pp. 5852 - 5869, http://dx.doi.org/10.1016/j.bmc.2018.10.034
    Journal articles | 2018
    Zhou Q; Reekie TA; Abbassi RH; Venkata DI; Font JS; Ryan RM; Rendina LM; Munoz L; Kassiou M, 2018, 'Flexible Analogues of Azaindole DYRK1A Inhibitors Elicit Cytotoxicity in Glioblastoma Cells', Australian Journal of Chemistry, 71, pp. 789 - 797, http://dx.doi.org/10.1071/CH18251
    Journal articles | 2018
    2018, 'Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors', , http://dx.doi.org/10.1016/j.ejmech.2017.10.059
    Journal articles | 2017
    Katte TA; Reekie TA; Werry EL; Jorgensen WT; Boyd R; Wong ECN; Gulliver DW; Connor M; Kassiou M, 2017, 'Investigation of pyrazolo-sulfonamides as putative small molecule oxytocin receptor agonists', European Journal of Medicinal Chemistry, 136, pp. 330 - 333, http://dx.doi.org/10.1016/j.ejmech.2017.05.013
    Journal articles | 2017
    Moir M; Chua SW; Reekie T; Martin AD; Ittner A; Ittner LM; Kassiou M, 2017, 'Ring-opened aminothienopyridazines as novel tau aggregation inhibitors', MedChemComm, 8, pp. 1275 - 1282, http://dx.doi.org/10.1039/c6md00306k
    Journal articles | 2017
    O'Brien-Brown J; Jackson A; Reekie TA; Barron ML; Werry EL; Schiavini P; McDonnell M; Munoz L; Wilkinson S; Noll B; Wang S; Kassiou M, 2017, 'Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists', European Journal of Medicinal Chemistry, 130, pp. 433 - 439, http://dx.doi.org/10.1016/j.ejmech.2017.02.060
    Journal articles | 2017
    Reekie TA; Gisselbrecht JP; Boudon C; Trapp N; Diederich F, 2017, 'Metal-acetylide addition to tetracyanoethylene', Tetrahedron Letters, 58, pp. 2414 - 2416, http://dx.doi.org/10.1016/j.tetlet.2017.05.009
    Journal articles | 2017
    Reekie TA; Sekita M; Urner LM; Bauroth S; Ruhlmann L; Gisselbrecht JP; Boudon C; Trapp N; Clark T; Guldi DM; Diederich F, 2017, 'Porphyrin Donor and Tunable Push–Pull Acceptor Conjugates—Experimental Investigation of Marcus Theory', Chemistry - A European Journal, 23, pp. 6357 - 6369, http://dx.doi.org/10.1002/chem.201700043
    Journal articles | 2017
    Reekie TA; Wilkinson SM; Law V; Hibbs DE; Ong JA; Kassiou M, 2017, 'Rapid access to N-(indol-2-yl)amides and N-(indol-3-yl)amides as unexplored pharmacophores', Organic and Biomolecular Chemistry, 15, pp. 576 - 580, http://dx.doi.org/10.1039/c6ob02622b
    Journal articles | 2017
    Sokias R; Werry EL; Chua SW; Reekie TA; Munoz L; Wong ECN; Ittner LM; Kassiou M, 2017, 'Determination and reduction of translocator protein (TSPO) ligand rs6971 discrimination', MedChemComm, 8, pp. 202 - 210, http://dx.doi.org/10.1039/c6md00523c
    Journal articles | 2017
    Sridharan S; Lepelletier FX; Trigg W; Banister S; Reekie T; Kassiou M; Gerhard A; Hinz R; Boutin H, 2017, 'Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats', Molecular Imaging and Biology, 19, pp. 77 - 89, http://dx.doi.org/10.1007/s11307-016-0984-3
    Journal articles | 2017
    Wong ECN; Reekie TA; Werry EL; O'Brien-Brown J; Bowyer SL; Kassiou M, 2017, 'Pharmacological evaluation of a novel series of urea, thiourea and guanidine derivatives as P2X7 receptor antagonists', Bioorganic and Medicinal Chemistry Letters, 27, pp. 2439 - 2442, http://dx.doi.org/10.1016/j.bmcl.2017.04.005
    Journal articles | 2017
    Zhou Q; Phoa AF; Abbassi RH; Hoque M; Reekie TA; Font JS; Ryan RM; Stringer BW; Day BW; Johns TG; Munoz L; Kassiou M, 2017, 'Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma', Journal of Medicinal Chemistry, 60, pp. 2052 - 2070, http://dx.doi.org/10.1021/acs.jmedchem.6b01840
    Journal articles | 2016
    Conroy T; Manohar M; Gong Y; Wilkinson SM; Webster M; Lieberman BP; Banister SD; Reekie TA; Mach RH; Rendina LM; Kassiou M, 2016, 'A systematic exploration of the effects of flexibility and basicity on sigma (σ) receptor binding in a series of substituted diamines', Organic and Biomolecular Chemistry, 14, pp. 9388 - 9405, http://dx.doi.org/10.1039/c6ob00615a
    Journal articles | 2016
    Donckele EJ; Reekie TA; Trapp N; Diederich F, 2016, 'ChemInform Abstract: Penta‐2,4‐dien‐1‐ones by Formal [3 + 2] Cycloaddition‐Rearrangement of Electron‐Deficient Diethyl 2‐(Dicyanomethylene)malonate with Alkynes.', ChemInform, 47, http://dx.doi.org/10.1002/chin.201625063
    Journal articles | 2016
    Donckele EJ; Reekie TA; Trapp N; Diederich F, 2016, 'Penta-2,4-dien-1-ones by Formal [3+2] Cycloaddition–Rearrangement of Electron-Deficient Diethyl 2-(Dicyanomethylene)malonate with Alk­ynes', European Journal of Organic Chemistry, 2016, pp. 716 - 724, http://dx.doi.org/10.1002/ejoc.201501473
    Journal articles | 2016
    Jorgensen WT; Gulliver DW; Werry EL; Reekie T; Connor M; Kassiou M, 2016, 'Flexible analogues of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin 1a receptors', European Journal of Medicinal Chemistry, 108, pp. 730 - 740, http://dx.doi.org/10.1016/j.ejmech.2015.11.050
    Journal articles | 2016
    Katte TA; Reekie TA; Jorgensen WT; Kassiou M, 2016, 'ChemInform Abstract: The Formation of Seven‐Membered Heterocycles under Mild Pictet—Spengler Conditions: A Route to Pyrazolo[3,4]benzodiazepines.', ChemInform, 47, http://dx.doi.org/10.1002/chin.201642188
    Journal articles | 2016
    Katte TA; Reekie TA; Jorgensen WT; Kassiou M, 2016, 'The Formation of Seven-Membered Heterocycles under Mild Pictet-Spengler Conditions: A Route to Pyrazolo[3,4]benzodiazepines', Journal of Organic Chemistry, 81, pp. 4883 - 4889, http://dx.doi.org/10.1021/acs.joc.6b00710
    Journal articles | 2016
    Reekie TA; Donckele EJ; Manenti G; Puentener S; Trapp N; Diederich F, 2016, 'ChemInform Abstract: A Three‐Step Synthesis of Tetrasubstituted NH‐Pyrroles.', ChemInform, 47, http://dx.doi.org/10.1002/chin.201637091
    Journal articles | 2016
    Reekie TA; Donckele EJ; Manenti G; Püntener S; Trapp N; Diederich F, 2016, 'A Three-Step Synthesis of Tetrasubstituted NH-Pyrroles', Organic Letters, 18, pp. 2252 - 2255, http://dx.doi.org/10.1021/acs.orglett.6b00890
    Journal articles | 2015
    Beels MT; Biaggio I; Reekie T; Chiu M; Diederich F, 2015, 'Two-photon absorption and spectroscopy of the lowest two-photon transition in small donor-acceptor-substituted organic molecules', Physical Review A - Atomic, Molecular, and Optical Physics, 91, http://dx.doi.org/10.1103/PhysRevA.91.043818
    Journal articles | 2015
    Beinat C; Reekie T; Banister SD; O'Brien-Brown J; Xie T; Olson TT; Xiao Y; Harvey A; O'Connor S; Coles C; Grishin A; Kolesik P; Tsanaktsidis J; Kassiou M, 2015, 'Structure-activity relationship studies of SEN12333 analogues: Determination of the optimal requirements for binding affinities at α7 nAChRs through incorporation of known structural motifs', European Journal of Medicinal Chemistry, 95, pp. 277 - 301, http://dx.doi.org/10.1016/j.ejmech.2015.03.025
    Journal articles | 2015
    Hicks C; Ramos L; Reekie TA; Narlawar R; Kassiou M; McGregor IS, 2015, 'WAY 267,464, a non-peptide oxytocin receptor agonist, impairs social recognition memory in rats through a vasopressin 1A receptor antagonist action', Psychopharmacology, 232, pp. 2659 - 2667, http://dx.doi.org/10.1007/s00213-015-3902-5
    Journal articles | 2015
    Reekie TA; Donckele EJ; Ruhlmann L; Boudon C; Trapp N; Diederich F, 2015, 'Ester-Substituted Electron-Poor Alkenes for Cycloaddition-Retroelectrocyclization (CA-RE) and Related Reactions', European Journal of Organic Chemistry, 2015, pp. 7264 - 7275, http://dx.doi.org/10.1002/ejoc.201501085
    Journal articles | 2014
    Banwell MG; Jones MT; Reekie TA; Schwartz BD; Tan SH; White LV, 2014, 'ChemInform Abstract: RANEY® Cobalt — An Underutilised Reagent for the Selective Cleavage of C—X and N—O Bonds', ChemInform, 45, http://dx.doi.org/10.1002/chin.201445264
    Journal articles | 2014
    Banwell MG; Jones MT; Reekie TA; Schwartz BD; Tan SH; White LV, 2014, 'RANEY® cobalt-an underutilised reagent for the selective cleavage of C-X and N-O bonds', Organic and Biomolecular Chemistry, 12, pp. 7433 - 7444, http://dx.doi.org/10.1039/c4ob00917g
    Journal articles | 2014
    Beinat C; Reekie T; Hibbs D; Xie T; Olson TT; Xiao Y; Harvey A; O'Connor S; Coles C; Tsanaktsidis J; Kassiou M, 2014, 'Investigations of amide bond variation and biaryl modification in analogues of α7 nAChR agonist SEN12333', European Journal of Medicinal Chemistry, 84, pp. 200 - 205, http://dx.doi.org/10.1016/j.ejmech.2014.07.029
    Journal articles | 2014
    Hicks C; Ramos L; Reekie T; Misagh GH; Narlawar R; Kassiou M; McGregor IS, 2014, 'Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: A biotelemetry study in rats', British Journal of Pharmacology, 171, pp. 2868 - 2887, http://dx.doi.org/10.1111/bph.12613
    Journal articles | 2014
    Reekie TA; Kavanagh ME; Longworth M; Kassiou M, 2014, 'ChemInform Abstract: Synthesis of Biologically Active Seven‐Membered‐Ring Heterocycles.', ChemInform, 45, http://dx.doi.org/10.1002/chin.201419187
    Journal articles | 2014
    Reekie TA; McGregor IS; Kassiou M, 2014, 'Pyrazolo[1,4]diazepines as non-peptidic probes of the oxytocin and vasopressin receptors', Tetrahedron Letters, 55, pp. 4568 - 4571, http://dx.doi.org/10.1016/j.tetlet.2014.06.022
    Journal articles | 2013
    Reekie TA; Banwell MG; Willis AC, 2013, 'ChemInform Abstract: Intramolecular Cycloaddition Reactions of cis‐1,2‐Dihydrocatechol Derivatives Incorporating C3‐Tethered Diazoketones, Nitrile Oxides, and Azides: Stereocontrolled Routes to Enantiomerically Pure Spiro[5.5]undecanes and Related Systems.', ChemInform, 44, http://dx.doi.org/10.1002/chin.201349063
    Journal articles | 2013
    Reekie TA; Banwell MG; Willis AC, 2013, 'Intramolecular cycloaddition reactions of cis -1,2-dihydrocatechol derivatives incorporating C3-tethered diazoketones, nitrile oxides, and azides: Stereocontrolled routes to enantiomerically pure spiro[5.5]undecanes and related systems', Journal of Organic Chemistry, 78, pp. 7100 - 7111, http://dx.doi.org/10.1021/jo400952u
    Journal articles | 2013
    Reekie TA; Kavanagh ME; Longworth M; Kassiou M, 2013, 'Synthesis of biologically active seven-membered-ring heterocycles', Synthesis (Germany), 45, pp. 3211 - 3227, http://dx.doi.org/10.1055/s-0033-1338549
    Journal articles | 2012
    Banwell MG; Jones MT; Reekie TA, 2012, 'ChemInform Abstract: The Palladium‐Catalyzed Ullmann Cross‐Coupling Reaction', ChemInform, 43, http://dx.doi.org/10.1002/chin.201202233
    Journal articles | 2012
    Reekie TA; Banwell MG; Willis AC, 2012, 'A raney-cobalt-mediated tandem reductive cyclization route to the 1,5-methanoazocino[4,3-b]indole framework of the uleine and strychnos alkaloids', Journal of Organic Chemistry, 77, pp. 10773 - 10781, http://dx.doi.org/10.1021/jo302132d
    Journal articles | 2012
    Tan SH; Banwell MG; Willis AC; Reekie TA, 2012, 'Application of a Raney-cobalt-mediated tandem reductive cyclization protocol to total syntheses of the aspidosperma alkaloids (±)- limaspermidine and (±)-1-acetylaspidoalbidine', Organic Letters, 14, pp. 5621 - 5623, http://dx.doi.org/10.1021/ol3026846
    Journal articles | 2009
    Austin KAB; Matveenko M; Reekie TA; Banwell MG, 2009, 'ChemInform Abstract: Chemoenzymatic Methods for the Enantioselective Assembly of Bioactive Natural Products', ChemInform, 40, http://dx.doi.org/10.1002/chin.200945238
    Journal articles | 2008
    Reekie TA; Austin KAB; Banwell MG; Willis AC, 2008, 'ChemInform Abstract: The Chemoenzymatic Total Synthesis of Phellodonic Acid, a Biologically Active and Highly Functionalized Hirsutane Derivative Isolated from the Tasmanian Fungus Phellodon melaleucus.', ChemInform, 39, http://dx.doi.org/10.1002/chin.200826188
    Journal articles | 2008
    Reekie TA; Austin KAB; Banwell MG; Willis AC, 2008, 'The chemoenzymatic total synthesis of phellodonic acid, a biologically active and highly functionalized hirsutane derivative isolated from the tasmanian fungus phellodon melaleucus', Australian Journal of Chemistry, 61, pp. 94 - 106, http://dx.doi.org/10.1071/CH07403
  • Preprints | 2023
    Stuart CD; White NG; Barrow RA; Reekie TA, 2023, Synthesis and spectroscopic investigation of substituted piperazine-2,5-dione derivatives, , http://dx.doi.org/10.26434/chemrxiv-2023-sw036
    Conference Papers | 2018
    2018, 'Neuroinflammation in progressive multiple sclerosis: in vivo assessment using [18F]DPA714'
    Conference Papers | 2015
    Beels MT; Biaggio I; Reekie T; Chiu M; Diederich F, 2015, 'Extremely efficient two-photon absorption in small donor-acceptor substituted organic molecules', in Proceedings of Frontiers in Optics 2015, FIO 2015, http://dx.doi.org/10.1364/fio.2015.fw4a.2
    Preprints |
    Gunawan GA; Gimła M; Gardiner MG; Herman-Antosiewicz A; Reekie T, Divergent Reactivity of Usnic Acid and Evaluation of its Derivatives for Antiproliferative Activity Against Cancer Cells, , http://dx.doi.org/10.2139/ssrn.4308225

The Peter Andrews Award for Innovation in Medicinal Chemistry/Chemical Biology (2022)

Young Tall Poppy Science Award (2020) for promoting science among students, teachers and an appreciation of science in the broader community.

My research uses organic synthesis techniques to create molecules for application in medicinal chemistry, materials and plant sciences. I have a strong focus on both commercialisation and publishing results in peer-reviewed journals. It is the latter area where I have made the significant impact, generating new compounds to treat substance use disorders and social disfunction. The success of this research has led to the establishment of a spin-out company, Kinoxis Therapeutics, where I continue to work as their Head of Chemistry alongside my academic role.

Deputy Director of the Australian Chemistry Olympiad program

My Teaching

ZPEM1101 - Chemistry 1A

ZPEM1102 - Chemistry 1B

ZPEM2102 - Organic Chemistry 2

ZPEM2114 - Biological Chemistry