Associate Professor Wei Wen
Associate Professor

Associate Professor Wei Wen

BE, Ph.D.

Medicine & Health
Centre for Healthy Brain Ageing

Research Interests:
Computational neuroanatomy is about a comprehensive structural and functional model of the brain. The distribution of structural changes of human brain reflects the underlying pathology. The increasing sophistication of MRI allows neuroanatomical structures to be visualized in vivo in unprecedented detail. Clinical MRI is able to give good soft-tissue contrast and high spatial (<1 mm) resolution. Due to rapid advances in computing power and algorithm development, we are now well placed to study the extraordinary MRI-visible morphological variability of the human brain through mathematical models sensitive to subtle changes in neuroanatomical shape, complexity and tissue characteristics. One of the key requirements of neuroimaging research is the multi-disciplinary collaborations between neuroscience, engineering and medicine and a host of sub-disciplines. While the research subjects and the clinical needs are provided by medicine, the theoretical underpinnings come from mathematics and statistics, and the methodological approaches from computer science and biomedical engineering, all forming critical components of the enterprise. Our recent work includes mapping and modeling of cerebral white matter hyperintensities, algorithm development for examining the shapes and sizes of brain structures and cortical atrophy. fMRI, pMRI, MRS, and PET are also currently being used as brain imaging modalities in various studies.

Broad Research Areas:
Neurosciences, Brain Ageing, NeuroImaging / Neuro-radiology, Medical Informatics, Pattern Recognition & Data Mining, Markov models

Qualifications:
Ph.D. (Engineering, Sydney University)

Specific Research Keywords:
Computational neuroanatomy, Brain Anatomy, MRI, Mathematical Modelling, Medical Imaging

Meet Our Researcher
Click here to read Associate Professor Wei Wen's ‘Meet Our Researcher’ interview

Phone
+61 2 9385 0438
Location
Centre for Healthy Brain Ageing, Level 1, AGSM Building UNSW Sydney 2052, NSW
  • Book Chapters | 2001
    Sachdev PS; Loo CK; Mitchell PB; Gandevia SC; Taylor JL; Mcbride RS; Malhi GS; Wen W; Croker V; Elsayed H, 2001, 'Repetitive Transcranial Magnetic Stimulation (rTMS) for psychiatric disorders: The Sydney Studies', in Miyoshi K; Shapiro CM; Gaviria M; Morita Y (ed.), Contemporary Neuropsychiatry, Springer-Verlag, Tokyo, pp. 247 - 251, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000170062300039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
  • Journal articles | 2022
    Dima D; Modabbernia A; Papachristou E; Doucet GE; Agartz I; Aghajani M; Akudjedu TN; Albajes-Eizagirre A; Alnæs D; Alpert KI; Andersson M; Andreasen NC; Andreassen OA; Asherson P; Banaschewski T; Bargallo N; Baumeister S; Baur-Streubel R; Bertolino A; Bonvino A; Boomsma DI; Borgwardt S; Bourque J; Brandeis D; Breier A; Brodaty H; Brouwer RM; Buitelaar JK; Busatto GF; Buckner RL; Calhoun V; Canales-Rodríguez EJ; Cannon DM; Caseras X; Castellanos FX; Cervenka S; Chaim-Avancini TM; Ching CRK; Chubar V; Clark VP; Conrod P; Conzelmann A; Crespo-Facorro B; Crivello F; Crone EA; Dannlowski U; Dale AM; Davey C; de Geus EJC; de Haan L; de Zubicaray GI; den Braber A; Dickie EW; Di Giorgio A; Doan NT; Dørum ES; Ehrlich S; Erk S; Espeseth T; Fatouros-Bergman H; Fisher SE; Fouche JP; Franke B; Frodl T; Fuentes-Claramonte P; Glahn DC; Gotlib IH; Grabe HJ; Grimm O; Groenewold NA; Grotegerd D; Gruber O; Gruner P; Gur RE; Gur RC; Hahn T; Harrison BJ; Hartman CA; Hatton SN; Heinz A; Heslenfeld DJ; Hibar DP; Hickie IB; Ho BC; Hoekstra PJ; Hohmann S; Holmes AJ; Hoogman M; Hosten N; Howells FM; Hulshoff Pol HE; Huyser C; Jahanshad N; James A; Jernigan TL; Jiang J; Jönsson EG; Joska JA; Kahn R; Kalnin A, 2022, 'Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years', Human Brain Mapping, vol. 43, pp. 452 - 469, http://dx.doi.org/10.1002/hbm.25320
    Journal articles | 2022
    Sønderby IE; Ching CRK; Thomopoulos SI; van der Meer D; Sun D; Villalon-Reina JE; Agartz I; Amunts K; Arango C; Armstrong NJ; Ayesa-Arriola R; Bakker G; Bassett AS; Boomsma DI; Bülow R; Butcher NJ; Calhoun VD; Caspers S; Chow EWC; Cichon S; Ciufolini S; Craig MC; Crespo-Facorro B; Cunningham AC; Dale AM; Dazzan P; de Zubicaray GI; Djurovic S; Doherty JL; Donohoe G; Draganski B; Durdle CA; Ehrlich S; Emanuel BS; Espeseth T; Fisher SE; Ge T; Glahn DC; Grabe HJ; Gur RE; Gutman BA; Haavik J; Håberg AK; Hansen LA; Hashimoto R; Hibar DP; Holmes AJ; Hottenga JJ; Hulshoff Pol HE; Jalbrzikowski M; Knowles EEM; Kushan L; Linden DEJ; Liu J; Lundervold AJ; Martin-Brevet S; Martínez K; Mather KA; Mathias SR; McDonald-McGinn DM; McRae AF; Medland SE; Moberget T; Modenato C; Monereo Sánchez J; Moreau CA; Mühleisen TW; Paus T; Pausova Z; Prieto C; Ragothaman A; Reinbold CS; Reis Marques T; Repetto GM; Reymond A; Roalf DR; Rodriguez-Herreros B; Rucker JJ; Sachdev PS; Schmitt JE; Schofield PR; Silva AI; Stefansson H; Stein DJ; Tamnes CK; Tordesillas-Gutiérrez D; Ulfarsson MO; Vajdi A; van 't Ent D; van den Bree MBM; Vassos E; Vázquez-Bourgon J; Vila-Rodriguez F; Walters GB; Wen W; Westlye LT; Wittfeld K; Zackai EH; Stefánsson K; Jacquemont S, 2022, 'Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs', Human Brain Mapping, vol. 43, pp. 300 - 328, http://dx.doi.org/10.1002/hbm.25354
    Journal articles | 2022
    Wierenga LM; Doucet GE; Dima D; Agartz I; Aghajani M; Akudjedu TN; Albajes-Eizagirre A; Alnæs D; Alpert KI; Andreassen OA; Anticevic A; Asherson P; Banaschewski T; Bargallo N; Baumeister S; Baur-Streubel R; Bertolino A; Bonvino A; Boomsma DI; Borgwardt S; Bourque J; den Braber A; Brandeis D; Breier A; Brodaty H; Brouwer RM; Buitelaar JK; Busatto GF; Calhoun VD; Canales-Rodríguez EJ; Cannon DM; Caseras X; Castellanos FX; Chaim-Avancini TM; Ching CRK; Clark VP; Conrod PJ; Conzelmann A; Crivello F; Davey CG; Dickie EW; Ehrlich S; van't Ent D; Fisher SE; Fouche JP; Franke B; Fuentes-Claramonte P; de Geus EJC; Di Giorgio A; Glahn DC; Gotlib IH; Grabe HJ; Gruber O; Gruner P; Gur RE; Gur RC; Gurholt TP; de Haan L; Haatveit B; Harrison BJ; Hartman CA; Hatton SN; Heslenfeld DJ; van den Heuvel OA; Hickie IB; Hoekstra PJ; Hohmann S; Holmes AJ; Hoogman M; Hosten N; Howells FM; Hulshoff Pol HE; Huyser C; Jahanshad N; James AC; Jiang J; Jönsson EG; Joska JA; Kalnin AJ; Klein M; Koenders L; Kolskår KK; Krämer B; Kuntsi J; Lagopoulos J; Lazaro L; Lebedeva IS; Lee PH; Lochner C; Machielsen MWJ; Maingault S; Martin NG; Martínez-Zalacaín I; Mataix-Cols D; Mazoyer B; McDonald BC; McDonald C; McIntosh AM; McMahon KL; McPhilemy G, 2022, 'Greater male than female variability in regional brain structure across the lifespan', Human Brain Mapping, vol. 43, pp. 470 - 499, http://dx.doi.org/10.1002/hbm.25204
    Journal articles | 2021
    Alqarni A; Jiang J; Crawford JD; Koch F; Brodaty H; Sachdev P; Wen W, 2021, 'Sex differences in risk factors for white matter hyperintensities in non-demented older individuals', Neurobiology of Aging, vol. 98, pp. 197 - 204, http://dx.doi.org/10.1016/j.neurobiolaging.2020.11.001
    Journal articles | 2021
    Foo H; Thalamuthu A; Jiang J; Koch F; Mather KA; Wen W; Sachdev PS, 2021, 'Associations between Alzheimer's disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants', Neurobiology of Aging, vol. 98, pp. 108 - 115, http://dx.doi.org/10.1016/j.neurobiolaging.2020.11.002
    Journal articles | 2021
    Hairu R; Close JCT; Lord SR; Delbaere K; Wen W; Jiang J; Taylor ME, 2021, 'The association between white matter hyperintensity volume and gait performance under single and dual task conditions in older people with dementia: A cross-sectional study', Archives of Gerontology and Geriatrics, vol. 95, pp. 104427, http://dx.doi.org/10.1016/j.archger.2021.104427
    Journal articles | 2021
    Jia T; Chu C; Liu Y; van Dongen J; Papastergios E; Armstrong NJ; Bastin ME; Carrillo-Roa T; den Braber A; Harris M; Jansen R; Liu J; Luciano M; Ori APS; Roiz Santiañez R; Ruggeri B; Sarkisyan D; Shin J; Sungeun K; Tordesillas Gutiérrez D; van’t Ent D; Ames D; Artiges E; Bakalkin G; Banaschewski T; Bokde ALW; Brodaty H; Bromberg U; Brouwer R; Büchel C; Burke Quinlan E; Cahn W; de Zubicaray GI; Ehrlich S; Ekström TJ; Flor H; Fröhner JH; Frouin V; Garavan H; Gowland P; Heinz A; Hoare J; Ittermann B; Jahanshad N; Jiang J; Kwok JB; Martin NG; Martinot JL; Mather KA; McMahon KL; McRae AF; Nees F; Papadopoulos Orfanos D; Paus T; Poustka L; Sämann PG; Schofield PR; Smolka MN; Stein DJ; Strike LT; Teeuw J; Thalamuthu A; Trollor J; Walter H; Wardlaw JM; Wen W; Whelan R; Apostolova LG; Binder EB; Boomsma DI; Calhoun V; Crespo-Facorro B; Deary IJ; Hulshoff Pol H; Ophoff RA; Pausova Z; Sachdev PS; Saykin A; Wright MJ; Thompson PM; Schumann G; Desrivières S, 2021, 'Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group', Molecular Psychiatry, vol. 26, pp. 3884 - 3895, http://dx.doi.org/10.1038/s41380-019-0605-z
    Journal articles | 2021
    Shin J; Ma S; Hofer E; Patel Y; Vosberg DE; Tilley S; Roshchupkin GV; Sousa AMM; Jian X; Gottesman R; Mosley TH; Fornage M; Saba Y; Pirpamer L; Schmidt R; Schmidt H; Carrion-Castillo A; Crivello F; Mazoyer B; Bis JC; Li S; Yang Q; Luciano M; Karama S; Lewis L; Bastin ME; Harris MA; Wardlaw JM; Deary IE; Scholz M; Loeffler M; Witte AV; Beyer F; Villringer A; Armstrong NJ; Mather KA; Ames D; Jiang J; Kwok JB; Schofield PR; Thalamuthu A; Trollor JN; Wright MJ; Brodaty H; Wen W; Sachdev PS; Terzikhan N; Evans TE; Adams HHHH; Ikram MA; Frenzel S; van der Auwera-Palitschka S; Wittfeld K; Bülow R; Grabe HJ; Tzourio C; Mishra A; Maingault S; Debette S; Gillespie NA; Franz CE; Kremen WS; Ding L; Jahanshad N; Sestan N; Pausova Z; Seshadri S; Paus T, 2021, 'Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes', Cerebral Cortex, vol. 30, pp. 4121 - 4139, http://dx.doi.org/10.1093/CERCOR/BHAA035
    Journal articles | 2021
    Sønderby IE; van der Meer D; Moreau C; Kaufmann T; Walters GB; Ellegaard M; Abdellaoui A; Ames D; Amunts K; Andersson M; Armstrong NJ; Bernard M; Blackburn NB; Blangero J; Boomsma DI; Brodaty H; Brouwer RM; Bülow R; Bøen R; Cahn W; Calhoun VD; Caspers S; Ching CRK; Cichon S; Ciufolini S; Crespo-Facorro B; Curran JE; Dale AM; Dalvie S; Dazzan P; de Geus EJC; de Zubicaray GI; de Zwarte SMC; Desrivieres S; Doherty JL; Donohoe G; Draganski B; Ehrlich S; Eising E; Espeseth T; Fejgin K; Fisher SE; Fladby T; Frei O; Frouin V; Fukunaga M; Gareau T; Ge T; Glahn DC; Grabe HJ; Groenewold NA; Gústafsson Ó; Haavik J; Haberg AK; Hall J; Hashimoto R; Hehir-Kwa JY; Hibar DP; Hillegers MHJ; Hoffmann P; Holleran L; Holmes AJ; Homuth G; Hottenga JJ; Hulshoff Pol HE; Ikeda M; Jahanshad N; Jockwitz C; Johansson S; Jönsson EG; Jørgensen NR; Kikuchi M; Knowles EEM; Kumar K; Le Hellard S; Leu C; Linden DEJ; Liu J; Lundervold A; Lundervold AJ; Maillard AM; Martin NG; Martin-Brevet S; Mather KA; Mathias SR; McMahon KL; McRae AF; Medland SE; Meyer-Lindenberg A; Moberget T; Modenato C; Sánchez JM; Morris DW; Mühleisen TW; Murray RM; Nielsen J; Nordvik JE; Nyberg L; Loohuis LMO; Ophoff RA, 2021, '1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans', Translational Psychiatry, vol. 11, pp. 182, http://dx.doi.org/10.1038/s41398-021-01213-0
    Journal articles | 2021
    Tang J; Xu H; Liu Q; Zheng J; Pan C; Li Z; Wen W; Wang J; Zhu Q; Wang Z; Chen L, 2021, 'LncRNA LOC146880 Promotes Esophageal Squamous Cell Carcinoma Progression via miR-328-5p/FSCN1/MAPK axis', Aging, vol. 13, pp. 14198 - 14218, http://dx.doi.org/10.18632/aging.203037
    Journal articles | 2020
    Armstrong NJ; Mather KA; Sargurupremraj M; Knol MJ; Malik R; Satizabal CL; Yanek LR; Wen W; Gudnason VG; Dueker ND; Elliott LT; Hofer E; Bis J; Jahanshad N; Li S; Logue MA; Luciano M; Scholz M; Smith AV; Trompet S; Vojinovic D; Xia R; Alfaro-Almagro F; Ames D; Amin N; Amouyel P; Beiser AS; Brodaty H; Deary IJ; Fennema-Notestine C; Gampawar PG; Gottesman R; Griffanti L; Jack CR; Jenkinson M; Jiang J; Kral BG; Kwok JB; Lampe L; Liewald DCM; Maillard P; Marchini J; Bastin ME; Mazoyer B; Pirpamer L; Romero JR; Roshchupkin GV; Schofield PR; Schroeter ML; Stott DJ; Thalamuthu A; Trollor J; Tzourio C; van der Grond J; Vernooij MW; Witte VA; Wright MJ; Yang Q; Morris Z; Siggurdsson S; Psaty B; Villringer A; Schmidt H; Haberg AK; van Duijn CM; Wouter Jukema J; Dichgans M; Sacco RL; Wright CB; Kremen WS; Becker LC; Thompson PM; Mosley TH; Wardlaw JM; Ikram MA; Adams HHH; Seshadri S; Sachdev PS; Smith SM; Launer L; Longstreth W; DeCarli C; Schmidt R; Fornage M; Debette S; Nyquist PA, 2020, 'Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities', Stroke, vol. 51, pp. 2112 - 2121, http://dx.doi.org/10.1161/STROKEAHA.119.027544
    Journal articles | 2020
    Beaudet G; Tsuchida A; Petit L; Tzourio C; Caspers S; Schreiber J; Pausova Z; Patel Y; Paus T; Schmidt R; Pirpamer L; Sachdev PS; Brodaty H; Kochan N; Trollor J; Wen W; Armstrong NJ; Deary IJ; Bastin ME; Wardlaw JM; Munõz Maniega S; Witte AV; Villringer A; Duering M; Debette S; Mazoyer B, 2020, 'Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study', Frontiers in Psychiatry, vol. 11, pp. 342, http://dx.doi.org/10.3389/fpsyt.2020.00342
    Journal articles | 2020
    Broadhouse KM; Singh MF; Suo C; Gates N; Wen W; Brodaty H; Jain N; Wilson GC; Meiklejohn J; Singh N; Baune BT; Baker M; Foroughi N; Wang Y; Kochan N; Ashton K; Brown M; Li Z; Mavros Y; Sachdev PS; Valenzuela M, 2020, 'Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI', NeuroImage: Clinical, vol. 25, pp. 102182 - 102182, http://dx.doi.org/10.1016/j.nicl.2020.102182
    Journal articles | 2020
    Foo H; Thalamuthu A; Jiang J; Koch F; Mather K; Wen W; Sachdev P, 2020, 'Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants', , http://dx.doi.org/10.1101/2020.10.24.20218925
    Journal articles | 2020
    Grasby KL; Jahanshad N; Painter JN; Colodro-Conde L; Bralten J; Hibar DP; Lind PA; Pizzagalli F; Ching CRK; McMahon MAB; Shatokhina N; Zsembik LCP; Thomopoulos SI; Zhu AH; Strike LT; Agartz I; Alhusaini S; Almeida MAA; Alnæs D; Amlien IK; Andersson M; Ard T; Armstrong NJ; Ashley-Koch A; Atkins JR; Bernard M; Brouwer RM; Buimer EEL; Bülow R; Bürger C; Cannon DM; Chakravarty M; Chen Q; Cheung JW; Couvy-Duchesne B; Dale AM; Dalvie S; de Araujo TK; de Zubicaray GI; de Zwarte SMC; den Braber A; Doan NT; Dohm K; Ehrlich S; Engelbrecht HR; Erk S; Fan CC; Fedko IO; Foley SF; Ford JM; Fukunaga M; Garrett ME; Ge T; Giddaluru S; Goldman AL; Green MJ; Groenewold NA; Grotegerd D; Gurholt TP; Gutman BA; Hansell NK; Harris MA; Harrison MB; Haswell CC; Hauser M; Herms S; Heslenfeld DJ; Ho NF; Hoehn D; Hoffmann P; Holleran L; Hoogman M; Hottenga JJ; Ikeda M; Janowitz D; Jansen IE; Jia T; Jockwitz C; Kanai R; Karama S; Kasperaviciute D; Kaufmann T; Kelly S; Kikuchi M; Klein M; Knapp M; Knodt AR; Krämer B; Lam M; Lancaster TM; Lee PH; Lett TA; Lewis LB; Lopes-Cendes I; Luciano M; Macciardi F; Marquand AF; Mathias SR; Melzer TR; Milaneschi Y, 2020, 'The genetic architecture of the human cerebral cortex', Science, vol. 367, http://dx.doi.org/10.1126/science.aay6690
    Journal articles | 2020
    Hofer E; Roshchupkin GV; Adams HHH; Knol MJ; Lin H; Li S; Zare H; Ahmad S; Armstrong NJ; Satizabal CL; Bernard M; Bis JC; Gillespie NA; Luciano M; Mishra A; Scholz M; Teumer A; Xia R; Jian X; Mosley TH; Saba Y; Pirpamer L; Seiler S; Becker JT; Carmichael O; Rotter JI; Psaty BM; Lopez OL; Amin N; van der Lee SJ; Yang Q; Himali JJ; Maillard P; Beiser AS; Decarli C; Karama S; Lewis L; Harris M; Bastin ME; Deary IJ; Witte AV; Beyer F; Loeffler M; Mather KA; Schofield PR; Thalamuthu A; Kwok JB; Wright MJ; Ames D; Trollor J; Jiang J; Brodaty H; Wen W; Vernooij MW; Hofman A; Uitterlinden AG; Niessen WJ; Wittfeld K; Bülow R; Völker U; Pausova Z; Pike GB; Maingault S; Crivello F; Tzourio C; Amouyel P; Mazoyer B; Neale MC; Franz CE; Lyons MJ; Panizzon MS; Andreassen OA; Dale AM; Logue M; Grasby KL; Jahanshad N; Painter JN; Colodro-Conde L; Bralten J; Hibar DP; Lind PA; Pizzagalli F; Stein JL; Thompson PM; Medland SE; Sachdev PS; Kremen WS; Wardlaw JM; Villringer A; van Duijn CM; Grabe HJ; Longstreth WT; Fornage M; Paus T; Debette S; Ikram MA; Schmidt H; Schmidt R; Seshadri S; Ching CRK, 2020, 'Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-18367-y
    Journal articles | 2020
    Li Q; Dong C; Liu T; Chen X; Perry A; Jiang J; Cheng J; Niu H; Kochan NA; Brodaty H; Sachdev PS; Wen W, 2020, 'Longitudinal Changes in Whole-Brain Functional Connectivity Strength Patterns and the Relationship With the Global Cognitive Decline in Older Adults', Frontiers in Aging Neuroscience, vol. 12, http://dx.doi.org/10.3389/fnagi.2020.00071
    Journal articles | 2020
    Liu H; Liu T; Jiang J; Cheng J; Liu Y; Li D; Dong C; Niu H; Li S; Zhang J; Brodaty H; Sachdev P; Wen W, 2020, 'Differential longitudinal changes in structural complexity and volumetric measures in community-dwelling older individuals', Neurobiology of Aging, http://dx.doi.org/10.1016/j.neurobiolaging.2020.02.023
    Journal articles | 2020
    Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, vol. 18, pp. 1613 - 1624, http://dx.doi.org/10.1016/j.csbj.2020.06.001
    Journal articles | 2020
    Samaras K; Makkar S; Crawford JD; Kochan NA; Wen W; Draper B; Trollor JN; Brodaty H; Sachdev PS, 2020, 'Metformin use is associated with slowed cognitive decline and reduced incident dementia in older adults with type 2 diabetes: The Sydney memory and ageing study', Diabetes Care, vol. 43, pp. 2691 - 2701, http://dx.doi.org/10.2337/dc20-0892
    Journal articles | 2020
    Sargurupremraj M; Suzuki H; Jian X; Sarnowski C; Evans TE; Bis JC; Eiriksdottir G; Sakaue S; Terzikhan N; Habes M; Zhao W; Armstrong NJ; Hofer E; Yanek LR; Hagenaars SP; Kumar RB; van den Akker EB; McWhirter RE; Trompet S; Mishra A; Saba Y; Satizabal CL; Beaudet G; Petit L; Tsuchida A; Zago L; Schilling S; Sigurdsson S; Gottesman RF; Lewis CE; Aggarwal NT; Lopez OL; Smith JA; Valdés Hernández MC; van der Grond J; Wright MJ; Knol MJ; Dörr M; Thomson RJ; Bordes C; Le Grand Q; Duperron MG; Smith AV; Knopman DS; Schreiner PJ; Evans DA; Rotter JI; Beiser AS; Maniega SM; Beekman M; Trollor J; Stott DJ; Vernooij MW; Wittfeld K; Niessen WJ; Soumaré A; Boerwinkle E; Sidney S; Turner ST; Davies G; Thalamuthu A; Völker U; van Buchem MA; Bryan RN; Dupuis J; Bastin ME; Ames D; Teumer A; Amouyel P; Kwok JB; Bülow R; Deary IJ; Schofield PR; Brodaty H; Jiang J; Tabara Y; Setoh K; Miyamoto S; Yoshida K; Nagata M; Kamatani Y; Matsuda F; Psaty BM; Bennett DA; De Jager PL; Mosley TH; Sachdev PS; Schmidt R; Warren HR; Evangelou E; Trégouët DA; de Andrade M; Basu S; Berr C; Brody JA; Chasman DI; Dartigues JF; Folsom AR; Germain M, 2020, 'Cerebral small vessel disease genomics and its implications across the lifespan', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-19111-2
    Journal articles | 2020
    Sønderby IE; Gústafsson Ó; Doan NT; Hibar DP; Martin-Brevet S; Abdellaoui A; Ames D; Amunts K; Andersson M; Armstrong NJ; Bernard M; Blackburn N; Blangero J; Boomsma DI; Bralten J; Brattbak HR; Brodaty H; Brouwer RM; Bülow R; Calhoun V; Caspers S; Cavalleri G; Chen CH; Cichon S; Ciufolini S; Corvin A; Crespo-Facorro B; Curran JE; Dale AM; Dalvie S; Dazzan P; de Geus EJC; de Zubicaray GI; de Zwarte SMC; Delanty N; den Braber A; Desrivières S; Donohoe G; Draganski B; Ehrlich S; Espeseth T; Fisher SE; Franke B; Frouin V; Fukunaga M; Gareau T; Glahn DC; Grabe H; Groenewold NA; Haavik J; Håberg A; Hashimoto R; Hehir-Kwa JY; Heinz A; Hillegers MHJ; Hoffmann P; Holleran L; Hottenga JJ; Hulshoff HE; Ikeda M; Jahanshad N; Jernigan T; Jockwitz C; Johansson S; Jonsdottir GA; Jönsson EG; Kahn R; Kaufmann T; Kelly S; Kikuchi M; Knowles EEM; Kolskår KK; Kwok JB; Hellard SL; Leu C; Liu J; Lundervold AJ; Lundervold A; Martin NG; Mather K; Mathias SR; McCormack M; McMahon KL; McRae A; Milaneschi Y; Moreau C; Morris D; Mothersill D; Mühleisen TW; Murray R; Nordvik JE; Nyberg L; Olde Loohuis LM; Ophoff R; Paus T; Pausova Z; Penninx B; Peralta JM; Pike B; Prieto C, 2020, 'Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular Psychiatry, (2020), 25, 3, (584-602), 10.1038/s41380-018-0118-1)', Molecular Psychiatry, vol. 25, pp. 692 - 695, http://dx.doi.org/10.1038/s41380-019-0358-8
    Journal articles | 2020
    Sønderby IE; Gústafsson Ó; Doan NT; Hibar DP; Martin-Brevet S; Abdellaoui A; Ames D; Amunts K; Andersson M; Armstrong NJ; Bernard M; Blackburn N; Blangero J; Boomsma DI; Bralten J; Brattbak HR; Brodaty H; Brouwer RM; Bülow R; Calhoun V; Caspers S; Cavalleri G; Chen CH; Cichon S; Ciufolini S; Corvin A; Crespo-Facorro B; Curran JE; Dale AM; Dalvie S; Dazzan P; de Geus EJC; de Zubicaray GI; de Zwarte SMC; Delanty N; den Braber A; Desrivières S; Donohoe G; Draganski B; Ehrlich S; Espeseth T; Fisher SE; Franke B; Frouin V; Fukunaga M; Gareau T; Glahn DC; Grabe H; Groenewold NA; Haavik J; Håberg A; Hashimoto R; Hehir-Kwa JY; Heinz A; Hillegers MHJ; Hoffmann P; Holleran L; Hottenga JJ; Hulshoff HE; Ikeda M; Jahanshad N; Jernigan T; Jockwitz C; Johansson S; Jonsdottir GA; Jönsson EG; Kahn R; Kaufmann T; Kelly S; Kikuchi M; Knowles EEM; Kolskår KK; Kwok JB; Hellard SL; Leu C; Liu J; Lundervold AJ; Lundervold A; Martin NG; Mather K; Mathias SR; McCormack M; McMahon KL; McRae A; Milaneschi Y; Moreau C; Morris D; Mothersill D; Mühleisen TW; Murray R; Nordvik JE; Nyberg L; Olde Loohuis LM; Ophoff R; Paus T; Pausova Z; Penninx B; Peralta JM; Pike B; Prieto C, 2020, 'Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia', Molecular Psychiatry, vol. 25, pp. 584 - 602, http://dx.doi.org/10.1038/s41380-018-0118-1
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    Ulanova M; Poljak A; Wen W; Bongers A; Gloag L; Gooding J; Tilley R; Sachdev P; Braidy N, 2020, 'Nanoparticles as contrast agents for the diagnosis of Alzheimer’s disease: a systematic review', Nanomedicine, http://dx.doi.org/10.2217/nnm-2019-0316
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    Van Der Meer D; Sønderby IE; Kaufmann T; Walters GB; Abdellaoui A; Ames D; Amunts K; Andersson M; Armstrong NJ; Bernard M; Blackburn NB; Blangero J; Boomsma DI; Brodaty H; Brouwer RM; Bülow R; Cahn W; Calhoun VD; Caspers S; Cavalleri GL; Ching CRK; Cichon S; Ciufolini S; Corvin A; Crespo-Facorro B; Curran JE; Dalvie S; Dazzan P; De Geus EJC; De Zubicaray GI; De Zwarte SMC; Delanty N; Den Braber A; Desrivieres S; Di Forti M; Doherty JL; Donohoe G; Ehrlich S; Eising E; Espeseth T; Fisher SE; Fladby T; Frei O; Frouin V; Fukunaga M; Gareau T; Glahn DC; Grabe HJ; Groenewold NA; Gústafsson Ó; Haavik J; Haberg AK; Hashimoto R; Hehir-Kwa JY; Hibar DP; Hillegers MHJ; Hoffmann P; Holleran L; Hottenga JJ; Hulshoff Pol HE; Ikeda M; Jacquemont S; Jahanshad N; Jockwitz C; Johansson S; Jönsson EG; Kikuchi M; Knowles EEM; Kwok JB; Le Hellard S; Linden DEJ; Liu J; Lundervold A; Lundervold AJ; Martin NG; Mather KA; Mathias SR; McMahon KL; McRae AF; Medland SE; Moberget T; Moreau C; Morris DW; Mühleisen TW; Murray RM; Nordvik JE; Nyberg L; Olde Loohuis LM; Ophoff RA; Owen MJ; Paus T; Pausova Z; Peralta JM; Pike B; Prieto C; Quinlan EB; Reinbold CS; Reis Marques T; Rucker JJH; Sachdev PS, 2020, 'Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region with Cortical and Subcortical Morphology and Cognition', JAMA Psychiatry, vol. 77, pp. 420 - 430, http://dx.doi.org/10.1001/jamapsychiatry.2019.3779
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    Zhang J; Li Z; Cao X; Zuo L; Wen W; Zhu W; Jiang J; Cheng J; Sachdev P; Liu T; Wang Y, 2020, 'Altered Prefrontal-Basal Ganglia Effective Connectivity in Patients With Poststroke Cognitive Impairment', FRONTIERS IN NEUROLOGY, vol. 11, http://dx.doi.org/10.3389/fneur.2020.577482
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    Chauhan G; Adams HHH; Satizabal CL; Bis JC; Teumer A; Sargurupremraj M; Hofer E; Trompet S; Hilal S; Smith AV; Jian X; Malik R; Traylor M; Pulit SL; Amouyel P; Mazoyer B; Zhu YC; Kaffashian S; Schilling S; Beecham GW; Montine TJ; Schellenberg GD; Kjartansson O; Guðnason V; Knopman DS; Griswold ME; Windham BG; Gottesman RF; Mosley TH; Schmidt R; Saba Y; Schmidt H; Takeuchi F; Yamaguchi S; Nabika T; Kato N; Rajan KB; Aggarwal NT; De Jager PL; Evans DA; Psaty BM; Rotter JI; Rice K; Lopez OL; Liao J; Chen C; Cheng CY; Wong TY; Ikram MK; van der Lee SJ; Amin N; Chouraki V; Destefano AL; Aparicio HJ; Romero JR; Maillard P; Decarli C; Wardlaw JM; Del C. Valdés Hernández M; Luciano M; Liewald D; Deary IJ; Starr JM; Bastin ME; Maniega SM; Slagboom PE; Beekman M; Deelen J; Uh HW; Lemmens R; Brodaty H; Wright MJ; Ames D; Boncoraglio GB; Hopewell JC; Beecham AH; Blanton SH; Wright CB; Sacco RL; Wen W; Thalamuthu A; Armstrong NJ; Chong E; Schofield PR; Kwok JB; van der Grond J; Stott DJ; Ford I; Jukema JW; Vernooij MW; Hofman A; Uitterlinden AG; van der Lugt A; Wittfeld K; Grabe HJ; Hosten N; von Sarnowski B; Völker U; Levi C; Jimenez-Conde J, 2019, 'Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting', Neurology, vol. 92, pp. E486 - E503, http://dx.doi.org/10.1212/WNL.0000000000006851
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    Cvejic RC; Hocking DR; Wen W; Georgiou-Karistianis N; Cornish KM; Godler DE; Rogers C; Trollor JN, 2019, 'Reduced caudate volume and cognitive slowing in men at risk of fragile X-associated tremor ataxia syndrome', Brain Imaging and Behavior, vol. 13, pp. 1128 - 1134, http://dx.doi.org/10.1007/s11682-018-9928-7
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    Du J; Wang Y; Zhi N; Geng J; Cao W; Yu L; Mi J; Zhou Y; Xu Q; Wen W; Sachdev P, 2019, 'Structural brain network measures are superior to vascular burden scores in predicting early cognitive impairment in post stroke patients with small vessel disease', NeuroImage: Clinical, vol. 22, pp. 101712, http://dx.doi.org/10.1016/j.nicl.2019.101712
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    Mewton L; Reppermund S; Crawford J; Bunce D; Wen W; Sachdev P, 2019, 'Cross-sectional and prospective inter-relationships between depressive symptoms, vascular disease and cognition in older adults', Psychological Medicine, vol. 49, pp. 2168 - 2176, http://dx.doi.org/10.1017/S0033291718002994
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    Paradise M; Seruga A; Crawford JD; Chaganti J; Thalamuthu A; Kochan NA; Brodaty H; Wen W; Sachdev PS, 2019, 'The relationship of cerebral microbleeds to cognition and incident dementia in non-demented older individuals', Brain Imaging and Behavior, vol. 13, pp. 750 - 761, http://dx.doi.org/10.1007/s11682-018-9883-3
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    Paradise MB; Beaudoin MS; Dawes L; Crawford JD; Wen W; Brodaty H; Sachdev PS, 2019, 'Development and validation of a rating scale for perivascular spaces on 3T MRI', Journal of the Neurological Sciences, vol. 409, pp. 116621 - 116621, http://dx.doi.org/10.1016/j.jns.2019.116621
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    Parker N; Vidal-Pineiro D; French L; Shin J; Adams HHH; Brodaty H; Cox SR; Deary IJ; Fjell AM; Frenzel S; Grabe H; Hosten N; Ikram MA; Jiang J; Knol MJ; Mazoyer B; Mishra A; Sachdev PS; Salum G; Satizabal CL; Schmidt H; Schmidt R; Seshadri S; Schumann G; Völzke H; Walhovd KB; Wen W; Wittfeld K; Yang Q; Debette S; Pausova Z; Paus T, 2019, 'Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan', Cerebral Cortex, http://dx.doi.org/10.1093/cercor/bhz108
    Journal articles | 2019
    Samaras K; Makkar SR; Crawford JD; Kochan NA; Slavin MJ; Wen W; Trollor JN; Brodaty H; Sachdev PS, 2019, 'Effects of Statins on Memory, Cognition, and Brain Volume in the Elderly', Journal of the American College of Cardiology, vol. 74, pp. 2554 - 2568, http://dx.doi.org/10.1016/j.jacc.2019.09.041
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    Satizabal CL; Adams HHH; Hibar DP; White CC; Knol MJ; Stein JL; Scholz M; Sargurupremraj M; Jahanshad N; Roshchupkin GV; Smith AV; Bis JC; Jian X; Luciano M; Hofer E; Teumer A; van der Lee SJ; Yang J; Yanek LR; Lee TV; Li S; Hu Y; Koh JY; Eicher JD; Desrivières S; Arias-Vasquez A; Chauhan G; Athanasiu L; Rentería ME; Kim S; Hoehn D; Armstrong NJ; Chen Q; Holmes AJ; den Braber A; Kloszewska I; Andersson M; Espeseth T; Grimm O; Abramovic L; Alhusaini S; Milaneschi Y; Papmeyer M; Axelsson T; Ehrlich S; Roiz-Santiañez R; Kraemer B; Håberg AK; Jones HJ; Pike GB; Stein DJ; Stevens A; Bralten J; Vernooij MW; Harris TB; Filippi I; Witte AV; Guadalupe T; Wittfeld K; Mosley TH; Becker JT; Doan NT; Hagenaars SP; Saba Y; Cuellar-Partida G; Amin N; Hilal S; Nho K; Mirza-Schreiber N; Arfanakis K; Becker DM; Ames D; Goldman AL; Lee PH; Boomsma DI; Lovestone S; Giddaluru S; Le Hellard S; Mattheisen M; Bohlken MM; Kasperaviciute D; Schmaal L; Lawrie SM; Agartz I; Walton E; Tordesillas-Gutierrez D; Davies GE; Shin J; Ipser JC; Vinke LN; Hoogman M; Jia T; Burkhardt R; Klein M; Crivello F; Janowitz D; Carmichael O; Haukvik UK; Aribisala BS; Schmidt H, 2019, 'Genetic architecture of subcortical brain structures in 38,851 individuals', Nature Genetics, vol. 51, pp. 1624 - 1636, http://dx.doi.org/10.1038/s41588-019-0511-y
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    Taylor ME; Lord SR; Delbaere K; Wen W; Jiang J; Brodaty H; Kurrle SE; Stefanie Mikolaizak A; Close JCT, 2019, 'White matter hyperintensities are associated with falls in older people with dementia', Brain Imaging and Behavior, vol. 13, pp. 1265 - 1272, http://dx.doi.org/10.1007/s11682-018-9943-8
    Journal articles | 2018
    Dong C; Liu T; Wen W; Kochan NA; Jiang J; Li Q; Liu H; Niu H; Zhang W; Wang Y; Brodaty H; Sachdev PS, 2018, 'Altered functional connectivity strength in informant-reported subjective cognitive decline: A resting-state functional magnetic resonance imaging study', Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 10, pp. 688 - 697, http://dx.doi.org/10.1016/j.dadm.2018.08.011
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    Ghanavati T; Smitt MS; Lord SR; Sachdev PS; Wen W; Kochan NA; Brodaty H; Delbaere K, 2018, 'Deep white matter hyperintensities, microstructural integrity and dual task walking in older people', Brain Imaging and Behavior, vol. 12, pp. 1488 - 1496, http://dx.doi.org/10.1007/s11682-017-9787-7
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    Hyett MP; Perry A; Breakspear M; Wen W; Parker GB, 2018, 'White matter alterations in the internal capsule and psychomotor impairment in melancholic depression', PLoS ONE, vol. 13, http://dx.doi.org/10.1371/journal.pone.0195672
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    Jiang J; Paradise M; Liu T; Armstrong NJ; Zhu W; Kochan N; Brodaty H; Sachdev PS; Wen W, 2018, 'The association of regional white matter lesions with cognition in a community-based cohort of older individuals', NeuroImage: Clinical, vol. 19, pp. 14 - 21, http://dx.doi.org/10.1016/j.nicl.2018.03.035
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    Jiang J; Thalamuthu A; Ho JE; Mahajan A; Ek WE; Brown DA; Breit SN; Wang TJ; Gyllensten U; Chen MH; Enroth S; Januzzi JL; Lind L; Armstrong NJ; Kwok JB; Schofield PR; Wen W; Trollor JN; Johansson Å; Morris AP; Vasan RS; Sachdev PS; Mather KA, 2018, 'A meta-analysis of genome-wide association studies of growth differentiation factor-15 concentration in blood', Frontiers in Genetics, vol. 9, http://dx.doi.org/10.3389/fgene.2018.00097
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    Kong XZ; Mathias SR; Guadalupe T; Abé C; Agartz I; Akudjedu TN; Aleman A; Alhusaini S; Allen NB; Ames D; Andreassen OA; Vasquez AA; Armstrong NJ; Bergo F; Bastin ME; Batalla A; Bauer J; Baune BT; Baur-Streubel R; Biederman J; Blaine SK; Boedhoe P; Bøen E; Bose A; Bralten J; Brandeis D; Brem S; Brodaty H; Yüksel D; Brooks SJ; Buitelaar J; Bürger C; Bülow R; Calhoun V; Calvo A; Canales-Rodríguez EJ; Canive JM; Cannon DM; Caparelli EC; Castellanos FX; Cavalleri GL; Cendes F; Chaim-Avancini TM; Chantiluke K; Chen QL; Chen X; Cheng Y; Christakou A; Clark VP; Coghill D; Connolly CG; Conzelmann A; Córdova-Palomera A; Cousijn J; Crow T; Cubillo A; Dale A; Dannlowski U; De Bruttopilo SA; De Zeeuw P; Deary IJ; Delanty N; Demeter DV; Di Martino A; Dickie EW; Dietsche B; Doan NT; Doherty CP; Doyle A; Durston S; Earl E; Ehrlich S; Ekman CJ; Elvsåshagen T; Epstein JN; Fair DA; Faraone SV; Fernández G; Filho GB; Förster K; Fouche JP; Foxe JJ; Frodl T; Fuentes-Claramonte P; Fullerton J; Garavan H; Garcia DDS; Gotlib IH; Goudriaan AE; Grabe HJ; Groenewold NA; Grotegerd D; Gruber O; Gurholt T; Haavik J; Hahn T; Hansell NK; Harris MA; Hartman CA; Hernández MDCV, 2018, 'Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, pp. E5154 - E5163, http://dx.doi.org/10.1073/pnas.1718418115
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    Paradise M; Shepherd CE; Wen W; Sachdev PS, 2018, 'Neuroimaging and neuropathology indices of cerebrovascular disease burden: A systematic review', Neurology, vol. 91, pp. 310 - 320, http://dx.doi.org/10.1212/wnl.0000000000005997
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    Radd-Vagenas S; Fiatarone Singh MA; Inskip M; Mavros Y; Gates N; Wilson GC; Jain N; Meiklejohn J; Brodaty H; Wen W; Singh N; Baune BT; Suo C; Baker MK; Foroughi N; Sachdev PS; Valenzuela M; Flood VM, 2018, 'Reliability and validity of a Mediterranean diet and culinary index (MediCul) tool in an older population with mild cognitive impairment', British Journal of Nutrition, vol. 120, pp. 1189 - 1200, http://dx.doi.org/10.1017/S0007114518002428
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    Vojinovic D; Adams HH; Jian X; Yang Q; Smith AV; Bis JC; Teumer A; Scholz M; Armstrong NJ; Hofer E; Saba Y; Luciano M; Bernard M; Trompet S; Yang J; Gillespie NA; van der Lee SJ; Neumann A; Ahmad S; Andreassen OA; Ames D; Amin N; Arfanakis K; Bastin ME; Becker DM; Beiser AS; Beyer F; Brodaty H; Bryan RN; Bülow R; Dale AM; De Jager PL; Deary IJ; DeCarli C; Fleischman DA; Gottesman RF; van der Grond J; Gudnason V; Harris TB; Homuth G; Knopman DS; Kwok JB; Lewis CE; Li S; Loeffler M; Lopez OL; Maillard P; El Marroun H; Mather KA; Mosley TH; Muetzel RL; Nauck M; Nyquist PA; Panizzon MS; Pausova Z; Psaty BM; Rice K; Rotter JI; Royle N; Satizabal CL; Schmidt R; Schofield PR; Schreiner PJ; Sidney S; Stott DJ; Thalamuthu A; Uitterlinden AG; Valdés Hernández MC; Vernooij MW; Wen W; White T; Witte AV; Wittfeld K; Wright MJ; Yanek LR; Tiemeier H; Kremen WS; Bennett DA; Jukema JW; Paus T; Wardlaw JM; Schmidt H; Sachdev PS; Villringer A; Grabe HJ; Longstreth WT; van Duijn CM; Launer LJ; Seshadri S; Ikram MA; Fornage M, 2018, 'Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-06234-w
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    Zimmermann J; Perry A; Breakspear M; Schirner M; Sachdev P; Wen W; Kochan NA; Mapstone M; Ritter P; McIntosh AR; Solodkin A, 2018, 'Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models', NeuroImage: Clinical, vol. 19, pp. 240 - 251, http://dx.doi.org/10.1016/j.nicl.2018.04.017
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    Zimmermann J; Perry A; Breakspear M; Schirner M; Sachdev P; Wen W; Kochan NA; Mapstone M; Ritter P; McIntosh AR; Solodkin A, 2018, 'Differentiation of Alzheimer’s disease based on local and global parameters in personalized Virtual Brain models', , http://dx.doi.org/10.1101/277624
    Journal articles | 2017
    Brouwer RM; Panizzon MS; Glahn DC; Hibar DP; Hua X; Jahanshad N; Abramovic L; de Zubicaray GI; Franz CE; Hansell NK; Hickie IB; Koenis MMG; Martin NG; Mather KA; McMahon KL; Schnack HG; Strike LT; Swagerman SC; Thalamuthu A; Wen W; Gilmore JH; Gogtay N; Kahn RS; Sachdev PS; Wright MJ; Boomsma DI; Kremen WS; Thompson PM; Hulshoff Pol HE, 2017, 'Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group', Human Brain Mapping, vol. 38, pp. 4444 - 4458, http://dx.doi.org/10.1002/hbm.23672
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    Guadalupe T; Mathias SR; vanErp TGM; Whelan CD; Zwiers MP; Abe Y; Abramovic L; Agartz I; Andreassen OA; Arias-Vásquez A; Aribisala BS; Armstrong NJ; Arolt V; Artiges E; Ayesa-Arriola R; Baboyan VG; Banaschewski T; Barker G; Bastin ME; Baune BT; Blangero J; Bokde ALW; Boedhoe PSW; Bose A; Brem S; Brodaty H; Bromberg U; Brooks S; Büchel C; Buitelaar J; Calhoun VD; Cannon DM; Cattrell A; Cheng Y; Conrod PJ; Conzelmann A; Corvin A; Crespo-Facorro B; Crivello F; Dannlowski U; de Zubicaray GI; de Zwarte SMC; Deary IJ; Desrivières S; Doan NT; Donohoe G; Dørum ES; Ehrlich S; Espeseth T; Fernández G; Flor H; Fouche J-P; Frouin V; Fukunaga M; Gallinat J; Garavan H; Gill M; Suarez AG; Gowland P; Grabe HJ; Grotegerd D; Gruber O; Hagenaars S; Hashimoto R; Hauser TU; Heinz A; Hibar DP; Hoekstra PJ; Hoogman M; Howells FM; Hu H; Hulshoff Pol HE; Huyser C; Ittermann B; Jahanshad N; Jönsson EG; Jurk S; Kahn RS; Kelly S; Kraemer B; Kugel H; Kwon JS; Lemaitre H; Lesch K-P; Lochner C; Luciano M; Marquand AF; Martin NG; Martínez-Zalacaín I; Martinot J-L; Mataix-Cols D; Mather K; McDonald C; McMahon KL; Medland SE; Menchón JM; Morris DW; Mothersill O; Maniega SM; Mwangi B; Nakamae T; Nakao T; Narayanaswaamy JC; Nees F; Nordvik JE; Onnink AMH; Opel N; Ophoff R; Paillère Martinot M-L; Papadopoulos Orfanos D; Pauli P; Paus T; Poustka L; Reddy JY; Renteria ME; Roiz-Santiáñez R; Roos A; Royle NA; Sachdev P; Sánchez-Juan P; Schmaal L; Schumann G; Shumskaya E; Smolka MN; Soares JC; Soriano-Mas C; Stein DJ; Strike LT; Toro R; Turner JA; Tzourio-Mazoyer N; Uhlmann A; Hernández MV; van den Heuvel OA; van der Meer D; van Haren NEM; Veltman DJ; Venkatasubramanian G; Vetter NC; Vuletic D; Walitza S; Walter H; Walton E; Wang Z; Wardlaw J; Wen W; Westlye LT; Whelan R; Wittfeld K; Wolfers T; Wright MJ; Xu J; Xu X; Yun J-Y; Zhao J; Franke B; Thompson PM; Glahn DC; Mazoyer B; Fisher SE; Francks C, 2017, 'Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex', Brain Imaging and Behavior: an international journal, vol. 11, pp. 1497 - 1514, http://dx.doi.org/10.1007/s11682-016-9629-z
    Journal articles | 2017
    Guan H; Liu T; Jiang J; Tao D; Zhang J; Niu H; Zhu W; Wang Y; Cheng J; Kochan NA; Brodaty H; Sachdev P; Wen W, 2017, 'Classifying MCI subtypes in community-dwelling elderly using cross-sectional and longitudinal MRI-based biomarkers', Frontiers in Aging Neuroscience, vol. 9, http://dx.doi.org/10.3389/fnagi.2017.00309
    Journal articles | 2017
    Haynes BI; Bunce D; Kochan NA; Wen W; Brodaty H; Sachdev PS, 2017, 'Associations between reaction time measures and white matter hyperintensities in very old age', Neuropsychologia, vol. 96, pp. 249 - 255, http://dx.doi.org/10.1016/j.neuropsychologia.2017.01.021
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    Hibar DP; Adams HHH; Jahanshad N; Chauhan G; Stein JL; Hofer E; Renteria ME; Bis JC; Arias-Vasquez A; Ikram MK; Desrivières S; Vernooij MW; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beecham AH; Beiser A; Bernard M; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chen Q; Ching CRK; Chouraki V; Cuellar-Partida G; Crivello F; Den Braber A; Doan NT; Ehrlich S; Giddaluru S; Goldman AL; Gottesman RF; Grimm O; Griswold ME; Guadalupe T; Gutman BA; Hass J; Haukvik UK; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Jørgensen KN; Karbalai N; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liewald DCM; Lopez LM; Luciano M; MacAre C; Marquand AF; Matarin M; Mather KA; Mattheisen M; McKay DR; Milaneschi Y; Muñoz Maniega S; Nho K; Nugent AC; Nyquist P; Loohuis LMO; Oosterlaan J; Papmeyer M; Pirpamer L; Pütz B; Ramasamy A; Richards JS; Risacher SL; Roiz-Santiañez R; Rommelse N; Ropele S; Rose EJ; Royle NA; Rundek T; Sämann PG; Saremi A; Satizabal CL; Schmaal L; Schork AJ; Shen L; Shin J; Shumskaya E; Smith AV; Sprooten E; Strike LT; Teumer A, 2017, 'Novel genetic loci associated with hippocampal volume', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms13624
    Journal articles | 2017
    Koncz R; Mohan A; Dawes L; Thalamuthu A; Wright M; Ames D; Lee T; Wen W; Sachdev PS, 2017, 'Incidental findings on cerebral MRI in twins: the Older Australian Twins Study', Brain Imaging and Behavior: an international journal, vol. 12, pp. 860 - 869, http://dx.doi.org/10.1007/s11682-017-9747-2
    Journal articles | 2017
    Mavros Y; Gates N; Wilson GC; Jain N; Meiklejohn J; Brodaty H; Wen W; Singh N; Baune BT; Suo C; Baker MK; Foroughi N; Wang Y; Sachdev PS; Valenzuela M; Fiatarone Singh MA, 2017, 'Mediation of Cognitive Function Improvements by Strength Gains After Resistance Training in Older Adults with Mild Cognitive Impairment: Outcomes of the Study of Mental and Resistance Training', Journal of the American Geriatrics Society, vol. 65, pp. 550 - 559, http://dx.doi.org/10.1111/jgs.14542
    Journal articles | 2017
    Perry A; Wen W; Kochan N; Thalamuthu A; Sachdev P; Breakspear M, 2017, 'The independent influences of age and education on functional brain networks and cognition in healthy older adults', , http://dx.doi.org/10.1101/154898
    Journal articles | 2017
    Suo C; Gates N; Fiatarone Singh M; Saigal N; Wilson GC; Meiklejohn J; Sachdev P; Brodaty H; Wen W; Singh N; Baune BT; Baker M; Foroughi N; Wang Y; Valenzuela MJ, 2017, 'Midlife managerial experience is linked to late life hippocampal morphology and function', Brain Imaging and Behavior, vol. 11, pp. 333 - 345, http://dx.doi.org/10.1007/s11682-016-9649-8
    Journal articles | 2016
    Adams HHH; Hibar DP; Chouraki V; Stein JL; Nyquist PA; Rentería ME; Trompet S; Arias-Vasquez A; Seshadri S; Desrivières S; Beecham AH; Jahanshad N; Wittfeld K; Van Der Lee SJ; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beiser A; Bernard M; Bis JC; Blanken LME; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chauhan G; Chen Q; Ching CRK; Cuellar-Partida G; Braber AD; Doan NT; Ehrlich S; Filippi I; Ge T; Giddaluru S; Goldman AL; Gottesman RF; Greven CU; Grimm O; Griswold ME; Guadalupe T; Hass J; Haukvik UK; Hilal S; Hofer E; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liao J; Liewald DCM; Lopez LM; Luciano M; Macare C; Marquand A; Matarin M; Mather KA; Mattheisen M; Mazoyer B; McKay DR; McWhirter R; Milaneschi Y; Mirza-Schreiber N; Muetzel RL; Maniega SM; Nho K; Nugent AC; Loohuis LMO; Oosterlaan J; Papmeyer M; Pappa I; Pirpamer L; Pudas S; Pütz B; Rajan KB; Ramasamy A; Richards JS; Risacher SL; Roiz-Santiañez R; Rommelse N; Rose EJ; Royle NA; Rundek T; Sämann PG; Satizabal CL, 2016, 'Novel genetic loci underlying human intracranial volume identified through genome-wide association', Nature Neuroscience, vol. 19, pp. 1569 - 1582, http://dx.doi.org/10.1038/nn.4398
    Journal articles | 2016
    Franke B; van Hulzen KJE; Arias-Vasquez A; Bralten J; Hoogman M; Klein M; van Donkelaar MMJ; Hakobjan MMH; Heister AJGAM; Makkinje RRR; Naber MAM; van der Marel SSL; Mostert JC; Brunner HG; van Bokhoven H; Zwiers MP; Buitelaar JK; Fernández G; Fisher SE; Francks C; Stein JL; Hibar DP; Thompson PM; Ripke S; Anttila V; Neale BM; Farh KH; Bulik-Sullivan B; Huang H; Fromer M; Goldstein JI; Daly MJ; Walters RK; Smoller JW; Lee P; Belliveau RA; Bergen SE; Bevilacqua E; Chambert KD; Genovese G; O'Dushlaine C; Scolnick EM; McCarroll SA; Moran JL; Palotie A; Petryshen TL; Erk S; Heinz A; Mohnke S; Romanczuk-Seiferth N; Walter H; DeLisi LE; McCarley RW; Mesholam-Gately RI; Seidman LJ; Nichols TE; Neale MC; McIntosh AM; Papmeyer M; Sprooten E; Lawrie SM; Sussmann JE; McMahon FJ; Yao Y; Meyer-Lindenberg A; Schwarz E; Grimm O; Mattheisen M; Agerbo E; Demontis D; Hansen T; Mors O; Olsen L; Rasmussen HB; Børglum AD; Mortensen PB; Werge T; Andreassen OA; Brown AA; Athanasiu L; Hartberg CB; Haukvik U; Melle I; Gruber O; Kraemer B; Keil M; Sachdev PS; Mather KA; Thalamuthu A; Armstrong NJ; Assareh AA; Brodaty H; Reppermund S; Wen W; Roiz-Santiañez R; Perez-Iglesias R; Saykin AJ; Kim S; Nho K; Risacher SL, 2016, 'Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept', Nature Neuroscience, vol. 19, pp. 420 - 431, http://dx.doi.org/10.1038/nn.4228
    Journal articles | 2016
    Jiang J; Wen W; Sachdev PS, 2016, 'Macrophage inhibitory cytokine-1/growth differentiation factor 15 as a marker of cognitive ageing and dementia', Current Opinion in Psychiatry, vol. 29, pp. 181 - 186, http://dx.doi.org/10.1097/YCO.0000000000000225
    Journal articles | 2016
    Lupton MK; Strike L; Hansell NK; Wen W; Mather KA; Armstrong NJ; Thalamuthu A; McMahon KL; de Zubicaray GI; Assareh AA; Simmons A; Proitsi P; Powell JF; Montgomery GW; Hibar DP; Westman E; Tsolaki M; Kloszewska I; Soininen H; Mecocci P; Velas B; Lovestone S; Brodaty H; Ames D; Trollor JN; Martin NG; Thompson PM; Sachdev PS; Wright MJ, 2016, 'The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume', Neurobiology of Aging, vol. 40, pp. 68 - 77, http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.023
    Journal articles | 2016
    Poljak A; Crawford JD; Smythe GA; Brodaty H; Slavin MJ; Kochan NA; Trollor JN; Wen W; Mather KA; Assareh AA; Ng PC; Sachdev PS, 2016, 'The relationship between plasma aβ levels, cognitive function and brain volumetrics: Sydney memory and ageing study', Current Alzheimer Research, vol. 13, pp. 243 - 255, http://dx.doi.org/10.2174/1567205013666151218150202
    Journal articles | 2016
    Sachdev PS; Thalamuthu A; Mather KA; Ames D; Wright MJ; Wen W; Bowden J; Lee T; Brodaty H; Crawford J; Duckworth T; Kang K; Garden N; Martin N; Lemmon C, 2016, 'White Matter Hyperintensities Are under Strong Genetic Influence', Stroke, vol. 47, pp. 1422 - 1428, http://dx.doi.org/10.1161/STROKEAHA.116.012532
    Journal articles | 2016
    Suo C; Singh MF; Gates N; Wen W; Sachdev P; Brodaty H; Saigal N; Wilson GC; Meiklejohn J; Singh N; Baune BT; Baker M; Foroughi N; Wang Y; Mavros Y; Lampit A; Leung I; Valenzuela MJ, 2016, 'Erratum: Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise', Molecular Psychiatry, http://dx.doi.org/10.1038/mp.2016.57
    Journal articles | 2016
    Suo C; Singh MF; Gates N; Wen W; Sachdev P; Brodaty H; Saigal N; Wilson GC; Meiklejohn J; Singh N; Baune BT; Baker M; Foroughi N; Wang Y; Mavros Y; Lampit A; Leung I; Valenzuela MJ, 2016, 'Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise', Molecular Psychiatry, vol. 21, pp. 1633 - 1642, http://dx.doi.org/10.1038/mp.2016.19
    Journal articles | 2016
    Wen W; Thalamuthu A; Mather KA; Zhu W; Jiang J; De Micheaux PL; Wright MJ; Ames D; Sachdev PS, 2016, 'Distinct Genetic Influences on Cortical and Subcortical Brain Structures', Scientific Reports, vol. 6, pp. 32760 - 32760, http://dx.doi.org/10.1038/srep32760
    Journal articles | 2016
    Yang Z; Wen W; Jiang J; Crawford JD; Reppermund S; Levitan C; Slavin MJ; Kochan NA; Richmond RL; Brodaty H; Trollor JN; Sachdev PS, 2016, 'Age-associated differences on structural brain MRI in nondemented individuals from 71 to 103 years', Neurobiology of Aging, vol. 40, pp. 86 - 97, http://dx.doi.org/10.1016/j.neurobiolaging.2016.01.006
    Journal articles | 2016
    Yang Z; Wen W; Jiang J; Crawford JD; Reppermund S; Levitan C; Slavin MJ; Kochan NA; Richmond RL; Brodaty H; Trollor JN; Sachdev PS, 2016, 'Structural MRI biomarkers of mild cognitive impairment from young elders to centenarians', Current Alzheimer Research, vol. 13, pp. 256 - 267, http://dx.doi.org/10.2174/1567205013666151218150534
    Journal articles | 2016
    Zhang H; Sachdev PS; Wen W; Crawford JD; Brodaty H; Baune BT; Kochan NA; Slavin MJ; Reppermund S; Kang K; Trollor JN, 2016, 'The relationship between inflammatory markers and voxel-based gray matter volumes in nondemented older adults', Neurobiology of Aging, vol. 37, pp. 138 - 146, http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.008
    Journal articles | 2015
    Birch RC; Hocking DR; Cornish KM; Menant JC; Georgiou-Karistianis N; Godler DE; Wen W; Hackett A; Rogers C; Trollor JN, 2015, 'Preliminary evidence of an effect of cerebellar volume on postural sway in FMR1 premutation males', Genes, Brain and Behavior, vol. 14, pp. 251 - 259, http://dx.doi.org/10.1111/gbb.12204
    Journal articles | 2015
    Boraxbekk CJ; Ames D; Kochan NA; Lee T; Thalamuthu A; Wen W; Armstrong NJ; Kwok JBJ; Schofield PR; Reppermund S; Wright MJ; Trollor JN; Brodaty H; Sachdev P; Mather KA, 2015, 'Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals', Neuropsychologia, vol. 78, pp. 10 - 17, http://dx.doi.org/10.1016/j.neuropsychologia.2015.09.031
    Journal articles | 2015
    Gautam P; Anstey KJ; Wen W; Sachdev PS; Cherbuin N, 2015, 'Cortical gyrification and its relationships with cortical volume, cortical thickness, and cognitive performance in healthy mid-life adults', Behavioural Brain Research, vol. 287, pp. 331 - 339, http://dx.doi.org/10.1016/j.bbr.2015.03.018
    Journal articles | 2015
    Hibar DP; Stein JL; Renteria ME; Arias-Vasquez A; Desrivières S; Jahanshad N; Toro R; Wittfeld K; Abramovic L; Andersson M; Aribisala BS; Armstrong NJ; Bernard M; Bohlken MM; Boks MP; Bralten J; Brown AA; Mallar Chakravarty M; Chen Q; Ching CRK; Cuellar-Partida G; Den Braber A; Giddaluru S; Goldman AL; Grimm O; Guadalupe T; Hass J; Woldehawariat G; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kim S; Klein M; Kraemer B; Lee PH; Olde Loohuis LM; Luciano M; MacAre C; Mather KA; Mattheisen M; Milaneschi Y; Nho K; Papmeyer M; Ramasamy A; Risacher SL; Roiz-Santiañez R; Rose EJ; Salami A; Sämann PG; Schmaal L; Schork AJ; Shin J; Strike LT; Teumer A; Van Donkelaar MMJ; Van Eijk KR; Walters RK; Westlye LT; Whelan CD; Winkler AM; Zwiers MP; Alhusaini S; Athanasiu L; Ehrlich S; Hakobjan MMH; Hartberg CB; Haukvik UK; Heister AJGAM; Hoehn D; Kasperaviciute D; Liewald DCM; Lopez LM; Makkinje RRR; Matarin M; Naber MAM; Reese McKay D; Needham M; Nugent AC; Pütz B; Royle NA; Shen L; Sprooten E; Trabzuni D; Van Der Marel SSL; Van Hulzen KJE; Walton E; Wolf C; Almasy L; Ames D; Arepalli S; Assareh AA; Bastin ME; Brodaty H; Bulayeva KB; Carless MA; Cichon S; Corvin A; Curran JE; Czisch M, 2015, 'Common genetic variants influence human subcortical brain structures', Nature, vol. 520, pp. 224 - 229, http://dx.doi.org/10.1038/nature14101
    Journal articles | 2015
    Jiang J; Trollor JN; Brown DA; Crawford JD; Thalamuthu A; Smith E; Breit SN; Liu T; Brodaty H; Baune BT; Sachdev PS; Wen W, 2015, 'An inverse relationship between serum macrophage inhibitory cytokine-1 levels and brain white matter integrity incommunity-dwelling older individuals', Psychoneuroendocrinology, vol. 62, pp. 80 - 88, http://dx.doi.org/10.1016/j.psyneuen.2015.07.610
    Journal articles | 2015
    Jiang J; Wen W; Brown DA; Crawford J; Thalamuthu A; Smith E; Breit SN; Liu T; Zhu W; Brodaty H; Baune BT; Trollor JN; Sachdev PS, 2015, 'The relationship of serum macrophage inhibitory cytokine - 1 levels with gray matter volumes in community-dwelling older individuals', PLoS ONE, vol. 10, pp. e0123399, http://dx.doi.org/10.1371/journal.pone.0123399
    Journal articles | 2015
    Mather KA; Armstrong NJ; Wen W; Kwok JB; Assareh AA; Thalamuthu A; Reppermund S; Duesing K; Wright MJ; Ames D; Trollor JN; Brodaty H; Schofield PR; Sachdev PS, 2015, 'Investigating the genetics of hippocampal volume in older adults without dementia', PLoS ONE, vol. 10, pp. e0116920, http://dx.doi.org/10.1371/journal.pone.0116920
    Journal articles | 2015
    Perry A; Wen W; Lord A; Thalamuthu A; Roberts G; Mitchell PB; Sachdev PS; Breakspear M, 2015, 'The organisation of the elderly connectome', NeuroImage, vol. 114, pp. 414 - 426, http://dx.doi.org/10.1016/j.neuroimage.2015.04.009
    Journal articles | 2015
    Tuerk C; Zhang H; Sachdev P; Lord SR; Brodaty H; Wen W; Delbaere K, 2015, 'Regional Gray Matter Volumes Are Related to Concern about Falling in Older People: A Voxel-Based Morphometric Study', Journals of Gerontology Series A Biological Sciences and Medical Sciences, vol. 71, pp. 138 - 144, http://dx.doi.org/10.1093/gerona/glu242
    Journal articles | 2014
    Assareh AA; Mather KA; Crawford JD; Wen W; Anstey KJ; Easteal S; Tan X; Mack HA; Kwok JBJ; Schofield PR; Sachdev PS, 2014, 'Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older australians', American Journal of Hypertension, vol. 27, pp. 1191 - 1198, http://dx.doi.org/10.1093/ajh/hpu035
    Journal articles | 2014
    Batouli SAH; Sachdev PS; Wen W; Trollor JN; Wright MJ; Ames D, 2014, 'Heritability of brain volumes in older adults: The Older Australian Twins Study', Neurobiology of Aging, vol. 35, pp. 937e5 - 937e18, http://dx.doi.org/10.1016/j.neurobiolaging.2013.10.079
    Journal articles | 2014
    Batouli SAH; Trollor JN; Wen W; Sachdev PS, 2014, 'The heritability of volumes of brain structures and its relationship to age: A review of twin and family studies', Ageing Research Reviews, vol. 13, pp. 1 - 9, http://dx.doi.org/10.1016/j.arr.2013.10.003
    Journal articles | 2014
    Callisaya ML; Srikanth VK; Lord SR; Close JC; Brodaty H; Sachdev PS; Phan T; Beare R; Trollor J; Wen W; Zheng JJ; Delbaere K, 2014, 'Sub-cortical infarcts and the risk of falls in older people: Combined results of TASCOG and Sydney MAS studies', International Journal of Stroke, vol. 9, pp. 55 - 60, http://dx.doi.org/10.1111/ijs.12279
    Journal articles | 2014
    Fiatarone Singh MA; Gates N; Saigal N; Wilson GC; Meiklejohn J; Brodaty H; Wen W; Singh N; Baune BT; Suo C; Baker MK; Foroughi N; Wang Y; Sachdev PS; Valenzuela M, 2014, 'The Study of Mental and Resistance Training (SMART) Study-Resistance Training and/or Cognitive Training in Mild Cognitive Impairment: A Randomized, Double-Blind, Double-Sham Controlled Trial', Journal of the American Medical Directors Association, vol. 15, pp. 873 - 880, http://dx.doi.org/10.1016/j.jamda.2014.09.010
    Journal articles | 2014
    Jiang J; Sachdev P; Lipnicki DM; Zhang H; Liu T; Suo C; Zhuang L; Crawford J; Reppermund S; Trollor J; Brodaty H; Wen W; Zhu W, 2014, 'A longitudinal study of brain atrophy over two years in community-dwelling older individuals', NeuroImage, vol. 86, pp. 203 - 211, http://dx.doi.org/10.1016/j.neuroimage.2013.08.022
    Journal articles | 2014
    Kanchibhotla SC; Mather KA; Thalamuthu A; Zhuang L; Schofield PR; Kwok JBJ; Ames D; Wright MJ; Trollor JN; Wen W; Sachdev PS, 2014, 'Genetics of microstructure of the corpus callosum in older adults', PLoS ONE, vol. 9, pp. e113181, http://dx.doi.org/10.1371/journal.pone.0113181
    Journal articles | 2014
    Raamana PR; Wen W; Kochan NA; Brodaty H; Sachdev PS; Wang L; Beg MF, 2014, 'Novel ThickNet features for the discrimination of amnestic MCI subtypes', NeuroImage: Clinical, vol. 6, pp. 284 - 295, http://dx.doi.org/10.1016/j.nicl.2014.09.005
    Journal articles | 2014
    Raamana PR; Wen W; Kochan NA; Brodaty H; Sachdev PS; Wang L; Beg MF, 2014, 'The sub-classification of amnestic mild cognitive impairment using MRI-based cortical thickness measures', Frontiers in Neurology, vol. 5 MAY, http://dx.doi.org/10.3389/fneur.2014.00076
    Journal articles | 2014
    Reppermund S; Zhuang L; Wen W; Slavin MJ; Trollor JN; Brodaty H; Sachdev PS, 2014, 'White matter integrity and late-life depression in community-dwelling individuals: Diffusion tensor imaging study using tract-based spatial statistics', British Journal of Psychiatry, vol. 205, pp. 315 - 320, http://dx.doi.org/10.1192/bjp.bp.113.142109
    Journal articles | 2014
    Sachdev PS; Lipnicki DM; Crawford JD; Wen W; Brodaty H, 2014, 'Progression of cognitive impairment in stroke/TIA patients over 3 years', Journal of neurology, neurosurgery, and psychiatry, vol. 85, pp. 1324 - 1330, http://dx.doi.org/10.1136/jnnp-2013-306776
    Journal articles | 2014
    Samaras K; Lutgers HL; Kochan NA; Crawford JD; Campbell LV; Wen W; Slavin MJ; Baune BT; Lipnicki DM; Brodaty H; Trollor JN; Sachdev PS, 2014, 'The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study', AGE, vol. 36, pp. 977 - 993, http://dx.doi.org/10.1007/s11357-013-9613-0
    Journal articles | 2014
    Thompson PM; Stein JL; Medland SE; Hibar DP; Vasquez AA; Renteria ME; Toro R; Jahanshad N; Schumann G; Franke B; Wright MJ; Martin NG; Agartz I; Alda M; Alhusaini S; Almasy L; Almeida J; Alpert K; Andreasen NC; Andreassen OA; Apostolova LG; Appel K; Armstrong NJ; Aribisala B; Bastin ME; Bauer M; Bearden CE; Bergmann Ø; Binder EB; Blangero J; Bockholt HJ; Bøen E; Bois C; Boomsma DI; Booth T; Bowman IJ; Bralten J; Brouwer RM; Brunner HG; Brohawn DG; Buckner RL; Buitelaar J; Bulayeva K; Bustillo JR; Calhoun VD; Cannon DM; Cantor RM; Carless MA; Caseras X; Cavalleri GL; Chakravarty MM; Chang KD; Ching CRK; Christoforou A; Cichon S; Clark VP; Conrod P; Coppola G; Crespo-Facorro B; Curran JE; Czisch M; Deary IJ; de Geus EJC; den Braber A; Delvecchio G; Depondt C; de Haan L; de Zubicaray GI; Dima D; Dimitrova R; Djurovic S; Dong H; Donohoe G; Duggirala R; Dyer TD; Ehrlich S; Ekman CJ; Elvsåshagen T; Emsell L; Erk S; Espeseth T; Fagerness J; Fears S; Fedko I; Fernández G; Fisher SE; Foroud T; Fox PT; Francks C; Frangou S; Frey EM; Frodl T; Frouin V; Garavan H; Giddaluru S; Glahn DC; Godlewska B; Goldstein RZ; Gollub RL; Grabe HJ, 2014, 'The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data', Brain Imaging and Behavior, vol. 8, pp. 153 - 182, http://dx.doi.org/10.1007/s11682-013-9269-5
    Journal articles | 2013
    Bunce D; Cherbuin N; Anstey KJ; Bielak AAM; Batterham PJ; Wen W; Sachdev P, 2013, 'Utility of intraindividual reaction time variability to predict white matter hyperintensities: A potential assessment tool for clinical contexts?', Journal of the International Neuropsychological Society, vol. 19, pp. 971 - 976, http://dx.doi.org/10.1017/S1355617713000830
    Journal articles | 2013
    Dobson-Stone C; Polly P; Korgaonkar M; Williams LM; Gordon E; Schofield PR; Mather KA; Armstrong N; Wen W; Sachdev PS; Kwok JB, 2013, 'GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals', PLoS One, vol. 8, pp. e71750, http://dx.doi.org/10.1371/journal.pone.0071750
    Journal articles | 2013
    Kanchibhotla SC; Mather KA; Wen W; Schofield PR; Kwok J; Sachdev PS, 2013, 'Genetics of ageing-related changes in brain white matter integrity - a review', Ageing Research Reviews, vol. 12, pp. 391 - 401, http://dx.doi.org/10.1016/j.arr.2012.10.003
    Journal articles | 2013
    Sachdev P; Lipnicki D; Crawford J; Reppermund S; Kochan N; Trollor J; Wen W; Draper B; Slavin M; Kang K; Lux O; Mather K; Brodaty H, 2013, 'Factors predicting reversion from mild cognitive impairment to normal cognition: a population-based study.', PLoS One, vol. 8, http://dx.doi.org/10.1371/journal.pone.0059649
    Journal articles | 2013
    Sachdev PS; Brodaty H; Levitan C; Slavin MJ; Richmond RL; Kochan NA; Wen W; Kang K; Mather KA, 2013, 'The Sydney Centenarian Study: methodology and profile of centenarians and near-centenarians', International Psychogeriatrics, vol. 25, pp. 993 - 1005, http://dx.doi.org/10.1017/S1041610213000197
    Journal articles | 2013
    Sachdev PS; Lee T; Wen W; Ames D; Batouli AH; Bowden J; Brodaty H; Chong E; Crawford J; Kang K; Mather K; Lammel A; Slavin MJ; Thalamuthu A; Trollor J; Wright MJ; OATS Research Team , 2013, 'The contribution of twins to the study of cognitive ageing and dementia: The Older Australian Twins Study', International Review of Psychiatry, vol. 25, pp. 738 - 747, http://dx.doi.org/10.3109/09540261.2013.870137
    Journal articles | 2013
    Sachdev PS; Zhuang L; Braidy N; Wen W, 2013, 'Is Alzheimer’s a disease of the white matter?', Current Opinion in Psychiatry, vol. 26, pp. 244 - 251, http://dx.doi.org/10.1097/YCO.0b013e32835ed6e8
    Journal articles | 2013
    Schilling S; DeStefano AL; Sachdev PS; Choi SH; Mather KA; DeCarli CD; Wen W; Høgh P; Raz N; Au R; Beiser A; Wolf PA; Romero JR; Zhu YC; Lunetta KL; Farrer L; Dufouil C; Kuller LH; Mazoyer B; Seshadri S; Tzourio C; Debette S, 2013, 'APOE genotype and MRI markers of cerebrovascular disease', Neurology, vol. 81, pp. 292 - 300, http://dx.doi.org/10.1212/WNL.0b013e31829bfda4
    Journal articles | 2013
    Wijeratne C; Sachdev S; Wen W; Piguet O; Lipnicki D; Malhi G; Mitchell PB; Sachdev PS, 2013, 'Hippocampal and amygdala volumes in an older bipolar disorder sample', International Psychogeriatrics, vol. 25, pp. 54 - 60, http://dx.doi.org/10.1017/S1041610212001469
    Journal articles | 2013
    Zhang H; Sachdev PS; Wen W; Kochan NA; Crawford JD; Brodaty H; Slavin MJ; Reppermund S; Kang K; Trollor JN, 2013, 'Grey matter correlates of three language tests in non-demented older adults', PLoS One, vol. 8, pp. e80215 - e80215, http://dx.doi.org/10.1371/journal.pone.0080215
    Journal articles | 2013
    Zhuang L; Sachdev PS; Trollor JN; Reppermund S; Kochan NA; Brodaty H; Wen W, 2013, 'Microstructural white matter changes, not hippocampal atrophy, detect early amnestic mild cognitive impairment', PLoS ONE, vol. 8, pp. e58887, http://dx.doi.org/10.1371/journal.pone.0058887
    Journal articles | 2012
    Quah-Smith JI; Wen W; Chen X; Williams ML; Sachdev PS, 2012, 'The brain effects of laser acupuncture in depressed individuals: an fMRI investigation', Medical Acupuncture, vol. 24, pp. 161 - 171, http://dx.doi.org/10.1089/acu.2011.0870
    Journal articles | 2012
    Song F; Poljak A; Crawford J; Kochan NA; Wen W; Cameron B; Lux O; Brodaty H; Mather K; Smythe GA; Sachdev PS, 2012, 'Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals', PLoS One, vol. 7, pp. e34078 - e34078, http://dx.doi.org/10.1371/journal.pone.0034078
    Journal articles | 2012
    Wen W; Lipnicki D; Beg MF; Jin JS; Luo SH; Zhu W; Kochan NA; Reppermund S; Zhuang L; Raamana PR; Liu T; Trollor JN; Wang L; Brodaty H; Sachdev PS; Cui Y, 2012, 'Automated detection of amnestic mild cognitive impairment in community-dwelling elderly adults: A combined spatial atrophy and white matter alteration approach', NeuroImage, vol. 59, pp. 1209 - 1217, http://dx.doi.org/10.1016/j.neuroimage.2011.08.013
    Journal articles | 2012
    Zhang H; Trollor JN; Sachdev PS; Wen W; Kochan NA; Crawford J; Brodaty H; Slavin MJ; Reppermund S; Draper B; Zhu W; Kang K, 2012, 'Gray Matter Atrophy Patterns of Mild Cognitive Impairment Subtypes', Journal of the Neurological Sciences, vol. 315, pp. 26 - 32, http://dx.doi.org/10.1016/j.jns.2011.12.011
    Journal articles | 2012
    Zheng J; Delbaere K; Close J; Sachdev PS; Wen W; Lord SR, 2012, 'White matter hyperintensities and impaired choice stepping reaction time in older people', Neurobiology of Aging, vol. 33, pp. 1177 - 1185, http://dx.doi.org/10.1016/j.neurobiolaging.2010.12.009
    Journal articles | 2012
    Zheng JJJ; Delbaere K; Close J; Sachdev PS; Wen W; Brodaty H; Lord SR, 2012, 'White matter hyperintensities are an independent predictor of physical decline in community-dwelling older people', Gerontology, vol. 58, pp. 398 - 406, http://dx.doi.org/10.1159/000337815
    Journal articles | 2012
    Zheng JJJ; Lord SR; Close JCT; Sachdev PS; Wen W; Brodaty H; Delbaere K, 2012, 'Brain white matter hyperintensities, executive dysfunction, instability, and falls in older people: A prospective cohort study', Journals of Gerontology, Series A : Biological Sciences and Medical Sciences, vol. 67, pp. 1085 - 1091, http://dx.doi.org/10.1093/gerona/gls063
    Journal articles | 2012
    Zhu W; Wen W; He Y; Xia A; Anstey KJ; Sachdev PS, 2012, 'Changing topological patterns in normal aging using large-scale structural networks', Neurobiology of Aging, vol. 33, pp. 899 - 913, http://dx.doi.org/10.1016/j.neurobiolaging.2010.06.022
    Journal articles | 2012
    Zhuang L; Sachdev PS; Trollor JN; Kochan NA; Reppermund S; Brodaty H; Wen W, 2012, 'Microstructural white matter changes in cognitively normal individuals at risk of cognitive decline', Neurology, vol. 79, pp. 748 - 754, http://dx.doi.org/10.1212/WNL.0b013e3182661f4d
    Journal articles | 2012
    Zhuang L; Wen W; Trollor JN; Kochan NA; Reppermund S; Brodaty H; Sachdev PS, 2012, 'Abnormalities of the fornix in mild cognitive impairment are related to episodic memory loss', Journal of Alzheimer's Disease, vol. 29, pp. 629 - 639, http://dx.doi.org/10.3233/jad-2012-111766
    Journal articles | 2011
    Liu T; Wen W; Zhu W; Kochan NA; Trollor JN; Reppermund S; Jin JS; Luo SH; Brodaty H; Sachdev PS, 2011, 'The relationship between cortical sulcal variability and cognitive performance in the elderly', Neuroimage, vol. 56, pp. 865 - 873, http://dx.doi.org/10.1016/j.neuroimage.2011.03.015
    Journal articles | 2011
    Quah-Smith I; Sachdev PS; Wen W; Chen X; Williams MA; Musil R, 2011, 'The brain effects of laser acupuncture in healthy individuals: an FMRI investigation', DEUTSCHE ZEITSCHRIFT FUR AKUPUNKTUR, vol. 54, pp. 22 - 23, http://dx.doi.org/10.1016/j.dza.2011.10.010
    Journal articles | 2011
    Wen W; He Y; Sachdev PS, 2011, 'Structural brain networks and neuropsychiatric disorders', Current Opinion in Psychiatry, vol. 24, pp. 219 - 225, http://dx.doi.org/10.1097/YCO.0b013e32834591f8
    Journal articles | 2011
    Wen W; Zhu W; He Y; Kochan NA; Reppermund S; Slavin MJ; Brodaty H; Crawford J; Xia A; Sachdev PS, 2011, 'Discrete Neuroanatomical Networks Are Associated with Specific Cognitive Abilities in Old Age', Journal of Neuroscience, vol. 31, pp. 1204 - 1212, http://dx.doi.org/10.1523/JNEUROSCI.4085-10.2011
    Journal articles | 2011
    Zhang H; Trollor JN; Wen W; Zhu W; Crawford J; Kochan NA; Slavin MJ; Brodaty H; Reppermund S; Kang K; Mather K; Sachdev PS, 2011, 'Grey matter atrophy of basal forebrain and hippocampus in mild cognitive impairment', Journal of Neurology Neurosurgery and Psychiatry, vol. 82, pp. 487 - 493, http://dx.doi.org/10.1136/jnnp.2010.217133
    Journal articles | 2010
    Javadapour A; Malhi ; Ivanoski B; Chen X; Wen W; Sachdev P, 2010, 'Hippocampal volumes in adults with bipolar disorder', Journal of Neuropsychiatry and Clinical Neurosciences, vol. 22, pp. 55 - 62, http://dx.doi.org/10.1176/appi.neuropsych.22.1.55
    Journal articles | 2009
    Chen X; Wen W; Anstey KJ; Sachdev PS, 2009, 'Prevalence, incidence, and risk factors of lacunar infarcts in a community sample', Neurology, vol. 73, pp. 266 - 272, http://dx.doi.org/10.1212/WNL.0b013e3181aa52ea
    Journal articles | 2009
    Christensen HM; Batterham PJ; Mackinnon A; Anstey KJ; Wen W; Sachdev PS, 2009, 'Education, atrophy, and cognitive change in an epidemiological sample in early old age', American Journal of Geriatric Psychiatry, vol. 17, pp. 218 - 226, http://dx.doi.org/10.1097/JGP.0b013e3181961a84
    Journal articles | 2009
    Chua TC; Wen W; Chen X; Kochan NA; Slavin MJ; Trollor JN; Brodaty H; Sachdev PS, 2009, 'Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment', American Journal of Geriatric Psychiatry, vol. 17, pp. 602 - 613, http://dx.doi.org/10.1097/JGP.0b013e3181a76e0b
    Journal articles | 2009
    Looi J; Tatham V; Kumar R; Maller JJ; Millard E; Wen W; Chen X; Brodaty H; Sachdev PS, 2009, 'Caudate nucleus volumes in stroke and vascular dementia', Psychiatry Research: Neuroimaging Section, vol. 174, pp. 67 - 75, http://dx.doi.org/10.1016/j.pscychresns.2009.04.002
    Journal articles | 2009
    Sachdev PS; Chen X; Brodaty H; Thompson C; Altendorf A; Wen W, 2009, 'The determinants and longitudinal course of post-stroke mild cognitive impairment', Journal of the International Neuropsychological Society, vol. 117, pp. 55 - 62, http://dx.doi.org/10.1017/S1355617709990579
    Journal articles | 2009
    Sachdev PS; Lammel A; Trollor JN; Lee T; Wright MJ; Ames D; Wen W; Martin NG; Brodaty H; Schofield PR; Lammel A, 2009, 'A comprehensive neuropsychiatric study of elderly twins: the older australian twin study', Twin research and human genetics, vol. 12, pp. 573 - 582, http://dx.doi.org/10.1375/twin.12.6.573
    Journal articles | 2009
    Sachdev PS; Parslow R; Wen W; Anstey KJ; Easteal S, 2009, 'Sex differences in the causes and consequences of white matter hyperintensities', Neurobiology of Aging, vol. 30, pp. 946 - 956, http://dx.doi.org/10.1016/j.neurobiolaging.2007.08.023
    Journal articles | 2009
    Wen W; Sachdev PS; Li JJ; Chen X; Anstey KJ, 2009, 'White matter hyperintensities in the forties: Their prevalence and topography in an epidemiological sample aged 44-48', Human Brain Mapping, vol. 30, pp. 1155 - 1167, http://dx.doi.org/10.1002/hbm.20586
    Journal articles | 2008
    Cherbuin N; Anstey K; Sachdev PS; Maller J; Meslin C; Mack H; Wen W; Easteal S, 2008, 'Total and regional gray matter volume is not related to APOE*E4 status in a community sample of middle-aged individuals', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 63, pp. 501 - 504, http://dx.doi.org/10.1093/gerona/63.5.501
    Journal articles | 2008
    Chua TC; Wen W; Slavin MJ; Sachdev PS, 2008, 'Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review', Current Opinion in Neurology, vol. 21, pp. 83 - 92, http://dx.doi.org/10.1097/WCO.0b013e3282f4594b
    Journal articles | 2008
    Kumar R; Anstey KJ; Cherbuin N; Wen W; Sachdev PS, 2008, 'Association of type 2 diabetes with depression, brain atrophy and reduced fine motor speed in a 60-64 year old community sample', American Journal of Geriatric Psychiatry, vol. 16, pp. 989 - 997, http://dx.doi.org/10.1097/JGP.0b013e31818b40fc
    Journal articles | 2008
    Sachdev PS; Chen X; Wen W; Anstey K, 2008, 'Light to moderate alcohol use is associated with increased cortical gray matter in middle-aged men: A voxel-based morphometric study', Psychiatry Research: Neuroimaging Section, vol. 163, pp. 61 - 69, http://dx.doi.org/10.1016/j.pscychresns.2007.08.009
    Journal articles | 2008
    Sachdev PS; Chen X; Wen W; Anstry K, 2008, 'White matter hyperintensities in mid-adult life', Current Opinion in Psychiatry, vol. 21, pp. 268 - 274, http://dx.doi.org/10.1097/YCO.0b013e3282f945d5
    Journal articles | 2008
    Sachdev PS; Mondraty NK; Wen W; Gulliford K, 2008, 'Brains of anorexia nervosa patients process self-images differently from non-self-images: an fMRI study', Neuropsychologia, vol. 46, pp. 2161 - 2168, http://dx.doi.org/10.1016/j.neuropsychologia.2008.02.031
    Journal articles | 2008
    Valenzuela MJ; Sachdev PS; Wen W; Chen X; Brodaty H, 2008, 'Lifespan mental activity predicts diminished rate of hippocampal atrophy', PLoS One, vol. 3, pp. 1 - 6, http://dx.doi.org/10.1371/journal.pone.0002598
    Journal articles | 2007
    Bunce D; Anstey KJ; Christensen H; Dear K; Wen W; Sachdev PS, 2007, 'White matter hyperintensities and within-person variability in community-dwelling adults aged 60-64 years', Neuropsychologia, vol. 45, pp. 2009 - 2015, http://dx.doi.org/10.1016/j.neuropsychologia.2007.02.006
    Journal articles | 2007
    Chen X; Wen W; Malhi GS; Ivanovski B; Sachdev PS, 2007, 'Regional gray matter changes in bipolar disorder: a voxel-based morphometric study', Australian and New Zealand Journal of Psychiatry, vol. 41, pp. 327 - 336, http://dx.doi.org/10.1080/00048670701213229
    Journal articles | 2007
    Javadpour A; Malhi GS; Ivanovski B; Chen X; Wen W; Sachdev PS, 2007, 'Increased anterior cingulate cortex volume in bipolar I disorder', Australian and New Zealand Journal of Psychiatry, vol. 41, pp. 910 - 916, http://dx.doi.org/10.1080/00048670701634978
    Journal articles | 2007
    Malhi GS; Ivanovski B; Wen W; Lagopoulos J; Moss K; Sachdev P, 2007, 'Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania', Acta Psychiatrica Scandinavica, vol. 116, pp. 57 - 66, http://dx.doi.org/10.1111/j.1600-0447.2007.01060.x
    Journal articles | 2007
    Maller JJ; Anstey KJ; Reglade-Meslin C; Christensen H; Wen W; Sachdev PS, 2007, 'Hippocampus and amygdala volumes in a random community-based sample of 60-64 year olds and their relationship to cognition', Psychiatry Research: Neuroimaging Section, vol. 156, pp. 185 - 197, http://dx.doi.org/10.1016/j.pscychresns.2007.06.005
    Journal articles | 2007
    Sachdev PS; Chen X; Joscelyne A; Wen W; Altendorf A; Brodaty H, 2007, 'Hippocampal size and dementia in stroke patients: the Sydney stroke study', Journal of the Neurological Sciences, vol. 260, pp. 71 - 77, http://dx.doi.org/10.1016/j.jns.2007.04.006
    Journal articles | 2007
    Sachdev PS; Wen W; Chen X; Brodaty H, 2007, 'Progression of white matter hyperintensities in elderly individuals over 3 years', Neurology, vol. 68, pp. 214 - 222, http://dx.doi.org/10.1212/01.wnl.0000251302.55202.73
    Journal articles | 2006
    Anstey K; Jorm A; Reglade-Meslin C; Maller J; Kumar R; von Sanden C; Windsor T; Rodgers B; Wen W; Sachdev PS, 2006, 'Weekly alcohol consumption, brain atrophy, and white matter hyperintensities in a community-based sample aged 60 to 64 years', Psychosomatic Medicine, vol. 68, pp. 778 - 785, http://dx.doi.org/10.1097/01.psy.0000237779.56500.af
    Journal articles | 2006
    Low L; Anstey KJ; Maller JJ; Kumar R; Wen W; Lux O; Salonikas C; Naidoo D; Sachdev PS, 2006, 'Hormone replacement therapy,brain volumes and white matter in postmenopausal women aged 60-64 years', Neuroreport, vol. 17, pp. 101 - 104, http://dx.doi.org/10.1097/01.wnr.0000194385.10622.8e
    Journal articles | 2006
    Ross AJ; Sachdev PS; Wen W; Brodaty H; Joscelyne A; Lorentz L, 2006, 'Prediction of cognitive decline after stroke using proton magnetic resonance spectroscopy', Journal of the Neurological Sciences, vol. 251, pp. 62 - 69, http://dx.doi.org/10.1016/j.jns.2006.08.014
    Journal articles | 2006
    Sachdev PS; Anstey KJ; Parslow R; Wen W; Maller JJ; Kumar R; Christensen H; Jorm AF, 2006, 'Pulmonary function, cognitive impairment and brain atrophy in a middle-aged community sample', Dementia and Geriatric Cognitive Disorders, vol. 21, pp. 300 - 308, http://dx.doi.org/10.1159/000091438
    Journal articles | 2006
    Sachdev PS; Brodaty H; Valenzuela MJ; Lorentz L; Looi JC; Berman K; Ross AJ; Wen W; Zagami AS, 2006, 'Clinical determinants of dementia and mild cognitive impairment following ischaemic stroke: The Sydney Stroke Study', Dementia and Geriatric Cognitive Disorders, vol. 21, pp. 275 - 283, http://dx.doi.org/10.1159/000091434
    Journal articles | 2006
    Wen W; Sachdev PS; Chen X; Anstey KJ, 2006, 'Gray matter reduction is correlated with white matter hyperintensity volume: A voxel-based morphometric study in a large epidemiological sample', Neuroimage, vol. 29, pp. 1031 - 1039, http://dx.doi.org/10.1016/j.neuroimage.2005.08.057
    Journal articles | 2005
    Sachdev PS, 2005, 'Should we distinguish between periventricular and deep white matter hyperintensities?', Stroke, vol. 36, pp. 2342 - 2343, http://dx.doi.org/10.1161/01.STR.0000185694.52347.6e
    Journal articles | 2005
    Sachdev PS; Parslow R; Lux O; Salonikas C; Wen W; Naidoo D; Christensen H; Jorm AF, 2005, 'Relationships of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample', Psychological Medicine, vol. 35, pp. 529 - 538, http://dx.doi.org/10.1017/S0033291704003721
    Journal articles | 2005
    Sachdev PS; Wen W; Christensen H; Jorm AF, 2005, 'White matter hyperintensities are related to physical disability and poor motor function', Journal of Neurology Neurosurgery and Psychiatry, vol. 76, pp. 362 - 367, http://dx.doi.org/10.1136/jnnp.2004.042945
    Journal articles | 2005
    Trollor JN; Sachdev PS; Haindl W; Brodaty H; Wen W; Walker BM, 2005, 'Regional cerebral blood flow deficits in mild Alzheimer's disease using high resolution single photon emission computerized tomography', Psychiatry and Clinical Neurosciences, vol. 59, pp. 280 - 290, http://dx.doi.org/10.1111/j.1440-1819.2005.01372.x
    Journal articles | 2004
    Jorm AF; Butterworth P; Anstey KJ; Christensen H; Easteal S; Maller J; Mather KA; Turakulov RI; Wen W; Sachdev PS, 2004, 'Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities', Psychological Medicine, vol. 34, pp. 1495 - 1506, http://dx.doi.org/10.1017/S0033291704003162
    Journal articles | 2004
    Sachdev PS; Brodaty H; Valenzuela MJ; Lorentz L; Looi JC; Wen W; Zagami AS, 2004, 'The neuropsychological profile of vascular cognitive impairment in stroke and TIA patients', Neurology, vol. 62, pp. 912 - 919, http://dx.doi.org/10.1212/01.WNL.0000115108.65264.4B
    Journal articles | 2004
    Sachdev PS; Parslow R; Salonikas C; Lux O; Wen W; Kumar R; Naidoo D; Christensen H; Jorm AF, 2004, 'Homocysteine and the brain in midadult life: evidence for an increased risk of leukoaraiosis in men', Archives of Neurology, vol. 61, pp. 1369 - 1376, http://dx.doi.org/10.1001/archneur.61.9.1369
    Journal articles | 2004
    Wen W; Sachdev PS, 2004, 'The topography of white matter hyperintensities on brain MRI in healthy 60- to 64-year-old individuals', Neuroimage, vol. 22, pp. 144 - 154, http://dx.doi.org/10.1016/j.neuroimage.2003.12.027
    Journal articles | 2003
    Loo CK; Mitchell PB; Croker V; Malhi GS; Wen W; Gandevia SC; Sachdev PS, 2003, 'Double-blind controlled investigation of bilateral prefrontal transcranial magnetic stimulation for the treatment of resistant major depression', Psychological Medicine, vol. 33, pp. 33 - 40, http://dx.doi.org/10.1017/S0033291702006839
    Journal articles | 2003
    Loo CK; Sachdev PS; Haindl W; Wen W; Mitchell PB; Croker V; Malhi GS, 2003, 'High (15 Hz) and low (1 Hz) frequency transcranial magnetic stimulation have different acute effects on regional cerebral blood flow in depressed patients', Psychological Medicine, vol. 33, pp. 997 - 1006, http://dx.doi.org/10.1017/S0033291703007955
    Journal articles | 2003
    Valenzuela MJ; Jones M; Wen W; Rae CD; Graham SL; Schnier R; Sachdev PS, 2003, 'Memory training alters hippocampal neurochemistry in healthy elderly', Neuroreport, vol. 14, pp. 1333 - 1337, http://dx.doi.org/10.1097/00001756-200307180-00010
    Journal articles | 2002
    Malhi GS; Valenzuela MJ; Wen W; Sachdev PS, 2002, 'Magnetic resonance spectroscopy and its applications in psychiatry', Australian and New Zealand Journal of Psychiatry, vol. 36, pp. 31 - 43, http://dx.doi.org/10.1046/j.1440-1614.2002.00992.x
    Journal articles | 2001
    Sachdev PS; Trollor JN; Walker A; Wen W; Fulham MJ; Smith JS; Matheson JM, 2001, 'Bilateral orbitomedial leucotomy for obsessive-compulsive disorder: a single-case study using positron emission tomography', Australian and New Zealand Journal of Psychiatry, vol. 35, pp. 684 - 690, http://dx.doi.org/10.1046/j.1440-1614.2001.00941.x
  • Preprints | 2020
    Wierenga L; Doucet G; Dima D; Agartz I; Aghajani M; Akudjedu T; Albajes-Eizagirre A; Alnæs D; Alpert K; Andreassen O; Anticevic A; Asherson P; Banaschewski T; Bargallo N; Baumeister S; Baur-Streubel R; Bertolino A; Bonvino A; Boomsma D; Borgwardt S; Bourque J; den Braber A; Brandeis D; Breier A; Brodaty H; Brouwer R; Buitelaar J; Busatto G; Calhoun V; Canales-Rodríguez E; Cannon D; Caseras X; Castellanos F; Chaim-Avancini T; Ching CRK; Clark V; Conrod P; Conzelmann A; Crivello F; Davey C; Dickie E; Ehrlich S; van ’t Ent D; Fisher S; Fouche J-P; Franke B; Fuentes-Claramonte P; de Geus EJC; Di Giorgio A; Glahn D; Gotlib I; Grabe H; Gruber O; Gruner P; Gur R; Gur R; Gurholt T; de Haan L; Haatveit B; Harrison B; Hartman C; Hatton S; Heslenfeld D; van den Heuvel O; Hickie I; Hoekstra P; Hohmann S; Holmes A; Hoogman M; Hosten N; Howells F; Hulshoff Pol H; Huyser C; Jahanshad N; James A; Jiang J; Jönsson E; Joska J; Kalnin A; Klein M; Koenders L; Kolskår K; Krämer B; Kuntsi J; Lagopoulos J; Lazaro L; Lebedeva I; Lee P; Lochner C; Machielsen MWJ; Maingault S; Martin N; Martínez-Zalacaín I; Mataix-Cols D; Mazoyer B; McDonald B; McDonald C; McIntosh A; McMahon K; McPhilemy G; van der Meer D; Menchón J; Naaijen J; Nyberg L; Oosterlaan J; Paloyelis Y; Pauli P; Pergola G; Pomarol-Clotet E; Portella M; Radua J; Reif A; Richard G; Roffman J; Rosa PGP; Sacchet M; Sachdev P; Salvador R; Sarró S; Satterthwaite T; Saykin A; Serpa M; Sim K; Simmons A; Smoller J; Sommer I; Soriano-Mas C; Stein D; Strike L; Szeszko P; Temmingh H; Thomopoulos S; Tomyshev A; Trollor J; Uhlmann A; Veer I; Veltman D; Voineskos A; Völzke H; Walter H; Wang L; Wang Y; Weber B; Wen W; West J; Westlye L; Whalley H; Williams SCR; Wittfeld K; Wolf D; Wright M; Yoncheva Y; Zanetti M; Ziegler G; de Zubicaray G; Thompson P; Crone E; Frangou S; Tamnes C; Karolinska Schizophrenia Project (KaSP) Consortium , 2020, Greater male than female variability in regional brain structure across the lifespan, http://dx.doi.org/10.1101/2020.02.17.952010
    Conference Posters | 2016
    Perry A; Wen W; Kochan N; Sachdev PS; Breakspear , 2016, 'The independent influences of age and education on functional brain networks and cognition in healthy older adults [Poster]', Vienna, Austria, Vol. 38, pp. 5094 - 5114, presented at Resting State and Brain Connectivity 2016, Vienna, Austria, 21 September 2016 - 23 September 2016, http://dx.doi.org/10.1002/hbm.23717
    Conference Abstracts | 2013
    Bhardwaj AK; Trollor J; Evans E; Brodaty H; Sachdev P; Schofield P; Mowat D; Wen W; Crawford J; Iacono T; Torr J, 2013, 'Successful ageing in older adults with intellectual disabilities: Predictors and correlates of cognitive decline [Abstract]', in Journal of Policy and Practice in Intellectual Disabilities, Wiley: 24 months, Tokyo, Japan, Vol. 10, pp. 107 - 108, presented at 3rd IASSIDD Asia-Pacific Conference, Tokyo, Japan, 22 August 2013 - 24 August 2013, http://dx.doi.org/10.1111/jppi.12029

1. Chief Investigator A (CIA): One ARC Discovery project (https://www.arc.gov.au/grants/discovery-program/discovery-projects ); and three NHMRC projects (https://nhmrc.gov.au/funding/find-funding/project-grants ).

2. Chief Investigator (CIx): NHMRC projects.

 

Current Research Themes:

  • Connectome of older brains – both structural and functional descriptions.
  • Longitudinal study of brain in older brains – atrophy, connectivity and functionality.
  • Predicting brain ageing trajectory using imaging, genetics and clinical data.
  • Mapping genetic influences on brain structures and functions with twins design.
  • Functional and structural connectivity and its cognitive relevance.
  • Development of computational algorithms to segment brain lesions – development of a pipeline for automatic lesion detection and computation.
  • Construction of a MRI index for measuring cerebrovascular disease (CVD) burden: a computational approach (together with Dr. Anbu Thalamuthu)

My Research Supervision

Ph.D. and Master's students, ILP and Honours students, and Postdoc fellows.