Dr Yafeng Ma

Conjoint Senior Lecturer
Medicine & Health
School of Clinical Medicine

Dr Yafeng Ma has been a part of the Ingham Institute for Applied Medical Research (Liverpool) since 2014. Dr Ma's transition from her previous extensive experience in cancer liquid biopsy, clinical trial studies, cancer cell biology, and molecular biology to the Obstetrics Research Group, under the guidance of Prof Jon Hyett, is a testament to her adaptability and versatility. Her knowledge and interests in cell free DNA, cell free RNA and exosomes have seamlessly transferred the area from cancer liquid biopsy to non-invasive prenatal diagnosis for maternal health studies.

From 2009-2013, Dr Ma had 4-year post-doctoral research at the Beatson Institute for Cancer Research (Glasgow, UK).

From 2004-2009, Dr Ma had her PhD training at Leiden University (The Netherlands).

Location
Ingham Institute for Applied Medical Research
  • Book Chapters | 2021
    Po JW; Ma Y; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'PD-L1 Detection on Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 223 - 233, http://dx.doi.org/10.1007/978-1-0716-1205-7_17
    Book Chapters | 2021
    Po JW; Ma Y; Luk AWS; Lynch D; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'Single-Cell Analysis of BRAFV600E and NRASQ61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 277 - 286, http://dx.doi.org/10.1007/978-1-0716-1205-7_21
  • Journal articles | 2024
    Ho V; Chung L; Wilkinson K; Ma Y; Rutland T; Lea V; Lim SH; Abubakar A; Ng W; Lee M; Roberts TL; Becker TM; Mackenzie S; Chua W; Lee CS, 2024, 'Microsatellite Instability Testing and Prognostic Implications in Colorectal Cancer', Cancers, 16, http://dx.doi.org/10.3390/cancers16112005
    Journal articles | 2024
    Nagata M; Horie S; Ma Y, 2024, 'Editorial: Circulating biomarkers in prostate cancer', Frontiers in Oncology, 14, http://dx.doi.org/10.3389/fonc.2024.1365353
    Journal articles | 2024
    Piper AK; Penney C; Holliday J; Tincknell G; Ma Y; Napaki S; Pantel K; Brungs D; Ranson M, 2024, 'EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma', International Journal of Molecular Sciences, 25, http://dx.doi.org/10.3390/ijms25105565
    Journal articles | 2023
    Grebstad Tune B; Sareen H; Powter B; Kahana-Edwin S; Cooper A; Koh ES; Lee CS; Po JW; McCowage G; Dexter M; Cain L; O’Neill G; Prior V; Karpelowsky J; Tsoli M; Baumbusch LO; Ziegler D; Roberts TL; DeSouza P; Becker TM; Ma Y, 2023, 'From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients', Biomedicines, 11, http://dx.doi.org/10.3390/biomedicines11112907
    Journal articles | 2023
    Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; de Souza P; Spring KJ, 2023, 'Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and Are Predictive of Response in Locally Advanced Rectal Cancer', Cancers, 15, http://dx.doi.org/10.3390/cancers15164184
    Journal articles | 2023
    Marivel AMJ; Ma Y; Becker TM; Verma A; Trieu S; Roberts TL; Ling SCW, 2023, 'The use of cell free DNA (cfDNA) for mutational screening of multiple myeloma', Leukemia Research Reports, 20, http://dx.doi.org/10.1016/j.lrr.2023.100393
    Journal articles | 2022
    Fatima S; Ma Y; Safrachi A; Haider S; Spring KJ; Vafaee F; Scott KF; Roberts TL; Becker TM; de Souza P, 2022, 'Harnessing Liquid Biopsies to Guide Immune Checkpoint Inhibitor Therapy', Cancers, 14, http://dx.doi.org/10.3390/cancers14071669
    Journal articles | 2022
    Ho V; Chung L; Lim SH; Ma Y; Wang B; Lea V; Abubakar A; Ng W; Lee M; Roberts TL; Chua W; Lee CS, 2022, 'Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer', Gastrointestinal Disorders, 4, pp. 165 - 179, http://dx.doi.org/10.3390/gidisord4030016
    Journal articles | 2022
    Khan T; Becker TM; Po JW; Chua W; Ma Y, 2022, 'Single-Circulating Tumor Cell Whole Genome Amplification to Unravel Cancer Heterogeneity and Actionable Biomarkers', International Journal of Molecular Sciences, 23, http://dx.doi.org/10.3390/ijms23158386
    Journal articles | 2022
    Khan T; Becker TM; Scott KF; Descallar J; de Souza P; Chua W; Ma Y, 2022, 'Prognostic and Predictive Value of Liquid Biopsy-Derived Androgen Receptor Variant 7 (AR-V7) in Prostate Cancer: A Systematic Review and Meta-Analysis', Frontiers in Oncology, 12, http://dx.doi.org/10.3389/fonc.2022.868031
    Journal articles | 2022
    Khan T; Lock JG; Ma Y; Harman DG; de Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, 'Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-20079-w
    Journal articles | 2022
    Sareen H; Ma Y; Becker TM; Roberts TL; de Souza P; Powter B, 2022, 'Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis', International journal of molecular sciences, 23, http://dx.doi.org/10.3390/ijms23168835
    Journal articles | 2022
    Young FP; Becker TM; Nimir M; Opperman T; Chua W; Balakrishnar B; de Souza P; Ma Y, 2022, 'Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11010257
    Journal articles | 2021
    Ma Y; Wang W, 2021, 'Original The impact of diagnosis related group payment on the performance of public hospitals', AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 13, pp. 6796 - 6801, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000668595100030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2020
    Khan T; Scott KF; Becker TM; Lock J; Nimir M; Ma Y; De Souza P, 2020, 'The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?', Prostate Cancer, 2020, http://dx.doi.org/10.1155/2020/7938280
    Journal articles | 2020
    Ma Y; Li L; Chen J; Chen T; Yuan C, 2020, 'Distinguishing rosacea from sensitive skin by reflectance confocal microscopy', SKIN RESEARCH AND TECHNOLOGY, 26, pp. 671 - +, http://dx.doi.org/10.1111/srt.12851
    Journal articles | 2019
    Ding PN; Becker T; Bray V; Chua W; Ma Y; Xu B; Lynch D; de Souza P; Roberts T, 2019, 'Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib', Thoracic Cancer, 10, pp. 1879 - 1884, http://dx.doi.org/10.1111/1759-7714.13154
    Journal articles | 2019
    Ding PN; Becker TM; Bray VJ; Chua W; Ma YF; Lynch D; Po J; Luk AWS; Caixeiro N; de Souza P; Roberts TL, 2019, 'The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study', Lung Cancer, 134, pp. 187 - 193, http://dx.doi.org/10.1016/j.lungcan.2019.06.021
    Journal articles | 2019
    Liu J; Mu Z; Liu L; Li K; Jiang R; Chen P; Zhou Q; Jin M; Ma Y; Xie Y; Xiang J; Li B; Ma Y; Mao X; Zhang L; Zhang T; Wu D, 2019, 'Frequency, clinical features and differential response to therapy of concurrent ALK/EGFR alterations in chinese lung cancer patients', Drug Design, Development and Therapy, 13, pp. 1809 - 1817, http://dx.doi.org/10.2147/DDDT.S196189
    Journal articles | 2019
    Nimir M; Ma Y; Jeffreys SA; Opperman T; Young F; Khan T; Ding P; Chua W; Balakrishnar B; Cooper A; Souza PD; Becker TM, 2019, 'Detection of AR-v7 in liquid biopsies of castrate resistant prostate cancer patients: A comparison of AR-v7 analysis in circulating tumor cells, circulating tumor RNA and exosomes', Cells, 8, http://dx.doi.org/10.3390/cells8070688
    Journal articles | 2019
    Po JW; Ma Y; Balakrishna B; Brungs D; Azimi F; De Souza P; Becker TM, 2019, 'Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status', PLoS ONE, 14, http://dx.doi.org/10.1371/journal.pone.0211866
    Journal articles | 2017
    Jiang G; Li R; Tang J; Ma Y; Hou X; Yang C; Guo W; Xin Y; Liu Y, 2017, 'Formulation of temozolomide-loaded nanoparticles and their targeting potential to melanoma cells', ONCOLOGY REPORTS, 37, pp. 995 - 1001, http://dx.doi.org/10.3892/or.2016.5342
    Journal articles | 2017
    Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, 18, http://dx.doi.org/10.3390/ijms18051047
    Journal articles | 2017
    Yuan C; Zheng S-L; Ma YF; Juliandri ; Philippe H, 2017, 'Cleanser use could decrease numbers of Demodex Folliculorum in mild to moderate acne patients', DERMATO-ENDOCRINOLOGY, 9, http://dx.doi.org/10.1080/19381980.2017.1348444
    Journal articles | 2016
    Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, 17, http://dx.doi.org/10.3390/ijms17081264
    Journal articles | 2015
    Ma Y; Faller WJ; Sansom OJ; Brown ER; Doig TN; Melton DW; Machesky LM, 2015, 'Fascin expression is increased in metastatic lesions but does not correlate with progression nor outcome in melanoma', Melanoma Research, 25, pp. 169 - 172, http://dx.doi.org/10.1097/CMR.0000000000000135
    Journal articles | 2015
    Ma Y; Machesky LM, 2015, 'Fascin1 in carcinomas: Its regulation and prognostic value', International Journal of Cancer, 137, pp. 2534 - 2544, http://dx.doi.org/10.1002/ijc.29260
    Journal articles | 2014
    Li A; Morton JP; Ma Y; Karim SA; Zhou Y; Faller WJ; Woodham EF; Morris HT; Stevenson RP; Juin A; Jamieson NB; Mackay CJ; Carter CR; Leung HY; Yamashiro S; Blyth K; Sansom OJ; Machesky LM, 2014, 'Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes', Gastroenterology, 146, pp. 1386, http://dx.doi.org/10.1053/j.gastro.2014.01.046
    Journal articles | 2013
    Ma Y; Li A; Faller WJ; Libertini S; Fiorito F; Gillespie DA; Sansom OJ; Yamashiro S; Machesky LM, 2013, 'Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation', Development (Cambridge), 140, pp. 2203 - 2211, http://dx.doi.org/10.1242/dev.089789
    Journal articles | 2013
    Ma Y; Li A; Faller WJ; Libertini S; Fiorito F; Gillespie DA; Sansom OJ; Yamashiro S; Machesky LM, 2013, 'Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation', Journal of Cell Science, 126, pp. e1 - e1, http://dx.doi.org/10.1242/jcs.135186
    Journal articles | 2013
    Ma Y; Reynolds LE; Li A; Stevenson RP; Hodivala-Dilke KM; Yamashiro S; Machesky LM, 2013, 'Fascin 1 is dispensable for developmental and tumour angiogenesis', Biology Open, 2, pp. 1187 - 1191, http://dx.doi.org/10.1242/bio.20136031
    Journal articles | 2013
    Sonego M; Gajendra S; Parsons M; Ma Y; Hobbs C; Zentar MP; Williams G; Machesky LM; Doherty P; Lalli G, 2013, 'Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain', Journal of Neuroscience, 33, pp. 12171 - 12185, http://dx.doi.org/10.1523/JNEUROSCI.0653-13.2013
    Journal articles | 2012
    Li A; Ma Y; Jin M; Mason S; Mort RL; Blyth K; Larue L; Sansom OJ; MacHesky LM, 2012, 'Activated mutant NRas Q61K drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism', Journal of Investigative Dermatology, 132, pp. 2610 - 2621, http://dx.doi.org/10.1038/jid.2012.186
    Journal articles | 2012
    Stevenson RP; Myant K; Jamieson T; Ma Y; Li A; Tan EH; Yamashiro S; Pignatelli M; Sansom O; Machesky LM, 2012, '178 Targeting the Actin Cytoskeletal Protein Fascin as a Novel Modulator of Intestinal Epithelial Cell Proliferation and Colon Cancer', Gastroenterology, 142, pp. S - 44, http://dx.doi.org/10.1016/s0016-5085(12)60167-x
    Journal articles | 2012
    Yu X; Zech T; McDonald L; Gonzalez EG; Li A; Macpherson I; Schwarz JP; Spence H; Futó K; Timpson P; Nixon C; Ma Y; Anton IM; Visegrády B; Insall RH; Oien K; Blyth K; Norman JC; Machesky LM, 2012, 'N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods', Journal of Cell Biology, 199, pp. 527 - 544, http://dx.doi.org/10.1083/jcb.201203025
    Journal articles | 2011
    Li A; Ma Y; Yu X; Mort RL; Lindsay CR; Stevenson D; Strathdee D; Insall RH; Chernoff J; Snapper SB; Jackson IJ; Larue L; Sansom OJ; Machesky LM, 2011, 'Rac1 Drives Melanoblast Organization during Mouse Development by Orchestrating Pseudopod- Driven Motility and Cell-Cycle Progression', Developmental Cell, 21, pp. 722 - 734, http://dx.doi.org/10.1016/j.devcel.2011.07.008
    Journal articles | 2010
    Ma Y; Machesky L, 2010, 'Fascin', AfCS-Nature Molecule Pages, http://dx.doi.org/10.1038/mp.a000904.01
    Journal articles | 2004
    Ma YF; Chen JH; Zhang DM; Wang XC, 2004, 'The antitumor activity of the extract from human urine', Chinese Pharmacological Bulletin, 20, pp. 69 - 71
  • Preprints | 2023
    Lim SH; Chua W; Ng W; Ip E; Marques TM; Tran NT; Gama-Carvalho M; Asghari R; Henderson C; Ma Y; De Souza P; Spring KJ, 2023, Circulating Tumour Cell Associated MicroRNA Profiles Change during Chemoradiation and are Predictive of Response in Locally Advanced Rectal Cancer, , http://dx.doi.org/10.20944/preprints202306.1821.v1
    Conference Abstracts | 2023
    Marivel A-MJ; Roberts TL; Descallar J; Aung WPP; Cheng J; Becker TM; James A; Ma Y; Bryant A; Ling S, 2023, 'Multiple Myeloma in the Culturally and Linguistically Diverse Southwestern Sydney, Australia', in Blood, American Society of Hematology, Vol. 142, pp. 6642 - 6642, http://dx.doi.org/10.1182/blood-2023-185193
    Preprints | 2022
    Khan T; Lock J; Ma Y; Harman D; Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells, , http://dx.doi.org/10.21203/rs.3.rs-1602818/v1
    Preprints | 2022
    Khan T; Lock J; Ma Y; Harman D; Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells, , http://dx.doi.org/10.21203/rs.3.rs-1602818/v2
    Conference Papers | 2021
    Tincknell G; Piper A-K; Ma Y; Ranson M; Becker T; Brungs D, 2021, 'Tracking circulating tumour DNA in patients with resectable gastroesophageal cancer', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 43 - 43, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000693805000079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Collier N; Oar A; Ng W; Johnston ML; Ma Y; Becker T; Apte M; Pavey D; Arumugam S; Merrett N; Asghari R; Lee MT, 2020, 'An Australian Three-Centre Feasibility Study of Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiotherapy for Locally Advanced Pancreatic Cancer with Collection of Baseline Circulating Tumor Cells', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, ELECTR NETWORK, Vol. 108, pp. E644 - E644, presented at 62nd Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), ELECTR NETWORK, 25 October 2020 - 28 October 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000582521502240&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Ding PN; Becker T; Bray VJ; Chua W; Ma YF; Luk A; Po J; Lynch D; Caixeiro N; de Souza P; Roberts TL, 2018, 'Longitudinal analysis of circulating biomarkers to monitor advanced EGFR mutated (EGFR+) non-small cell lung cancer (NSCLC)', in Annals of oncology : official journal of the European Society for Medical Oncology, pp. viii660, http://dx.doi.org/10.1093/annonc/mdy303.033
    Conference Abstracts | 2015
    Lim SH; Spring K; Chua W; Ng W; Descallar J; Ma Y; Becker TM; De Souza P, 2015, 'Circulating Tumor Cells in Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, TX, San Antonio, Vol. 93, pp. E522 - E523, presented at 57th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), TX, San Antonio, 18 October 2015 - 21 October 2015, http://dx.doi.org/10.1016/j.ijrobp.2015.07.1883
    Conference Papers | 2013
    Sonego M; Gajendra S; Parsons M; Ma Y; Hobbs C; Zentar MP; Williams G; Machesky LM; Doherty P; Lalli G, 2013, 'Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348700308&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Stevenson RP; Myant K; Jamieson T; Ma Y; Li A; Tan EH; Yamashiro S; Pignatelli M; Sansom O; Machesky LM, 2012, 'Targeting the Actin Cytoskeletal Protein Fascin as a Novel Modulator of Intestinal Epithelial Cell Proliferation and Colon Cancer', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, San Diego, pp. S44 - S44, presented at Digestive Disease Week (DDW), CA, San Diego, 19 May 2012 - 22 May 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306994300168&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1