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Mr Zifei Han

Mr Zifei Han

Postdoctoral Fellow

Doctor of Philosophy (Chemistry), Sep 2019 – Oct 2023

School of Chemistry, UNSW Sydney                                                        

Master of Science (Pharmaceutical Science Chemical Biology), Sep 2014 – Jul 2017 

School of Pharmacy, Peking University                                                                                                                                                                        

Bachelor of Science (Pharmacy), Sep 2010 – Jul 2014

School of Pharmacy, Peking University

Engineering
School of Chemical Engineering

Dr Zifei Han is a Postdoctoral Research Fellow at the Australian Centre for NanoMedicine (ACN) and an ECA Spinout Fellow at UNSW. He obtained his Scientia PhD in Chemistry from UNSW in 2023, following degrees in Pharmaceutical Sciences and Chemical Biology from Peking University. His research focuses on polymer therapeutics, nitric oxide (NO)-catalytic biomaterials and translational biomedical engineering, with interests in responsive sensing materials and application-driven biomaterials design. Alongside his academic research, he leads CooloMeter, an IP-protected pre-spinout program developing polymer-based cold-chain monitoring technology toward commercial translation. His experience spans biomaterials innovation, colorimetric sensor development and early-stage industry engagement.

Research Interests: RAFT polymerisation; Polymer Therapeutics; Nitric Oxide Biomaterials; NO-Catalytic Polymers; Surface Functionalisation; 3D-Printed Biomaterials; Translational Biomedical Engineering; Colorimetric Sensors.
E-mail
zifei.han@unsw.edu.au
Location
419, Science and Engineering Building (E8), UNSW Sydney, Kensington, NSW, 2052
  • Journal articles | 2026
    Adzlan SNA; Lin K; Geng S; Fan Q; Centurion F; Han Z; Mazur F; Chandrawati R, 2026, 'Nitric Oxide-Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant', Advanced Materials Interfaces, http://dx.doi.org/10.1002/admi.202501086
    Journal articles | 2026
    Zhou K; Han Z; Lin K; Wu D; Adzlan SNA; Fan Q; Cortez-Jugo C; Chandrawati R; Boyer C, 2026, 'Deployable 3D-Printed Vascular Stent with Surface-Catalysed Endogenous Nitric Oxide Generation', Advanced Materials, 38, http://dx.doi.org/10.1002/adma.202520199
    Journal articles | 2025
    Fan Q; Geng S; Rusli O; Mazur F; Han Z; Rijs NJ; Chandrawati R, 2025, 'Comprehensive evaluation of S-nitrosoglutathione and S-nitroso-N-acetylpenicillamine stability in biomedical contexts', Nitric Oxide Biology and Chemistry, 158, pp. 27 - 37, http://dx.doi.org/10.1016/j.niox.2025.05.006
    Journal articles | 2024
    Han Z; Li Z; Stenzel MH; Chapman R, 2024, 'Collapsed Star Copolymers Exhibiting Near Perfect Mimicry of the Therapeutic Protein “TRAIL”', Journal of the American Chemical Society, 146, pp. 22093 - 22102, http://dx.doi.org/10.1021/jacs.4c08658
    Journal articles | 2024
    Mazur F; Han Z; Tjandra AD; Chandrawati R, 2024, 'Digitalization of Colorimetric Sensor Technologies for Food Safety', Advanced Materials, 36, http://dx.doi.org/10.1002/adma.202404274
    Journal articles | 2023
    Han Z; Li Z; Raveendran R; Farazi S; Cao C; Chapman R; Stenzel MH, 2023, 'Peptide-Conjugated Micelles Make Effective Mimics of the TRAIL Protein for Driving Apoptosis in Colon Cancer', Biomacromolecules, 24, pp. 5046 - 5057, http://dx.doi.org/10.1021/acs.biomac.3c00668
    Journal articles | 2022
    Han Z; McAlpine SR; Chapman R, 2022, 'Delivering hydrophilic peptide inhibitors of heat shock protein 70 into cancer cells', Bioorganic Chemistry, 122, http://dx.doi.org/10.1016/j.bioorg.2022.105713
    Journal articles | 2022
    Li Z; Han Z; Stenzel MH; Chapman R, 2022, 'A High Throughput Approach for Designing Polymers That Mimic the TRAIL Protein', Nano Letters, 22, pp. 2660 - 2666, http://dx.doi.org/10.1021/acs.nanolett.1c04469
    Journal articles | 2018
    Tian C; Han Z; Li Y; Wang M; Yang J; Wang X; Zhang Z; Liu J, 2018, 'Synthesis and biological evaluation of 2,6-disubstituted-9H-purine, 2,4-disubstitued-thieno[3,2-d]pyrimidine and -7H-pyrrolo[2,3-d]pyrimidine analogues as novel CHK1 inhibitors', European Journal of Medicinal Chemistry, 151, pp. 836 - 848, http://dx.doi.org/10.1016/j.ejmech.2018.03.075
    Journal articles | 2017
    Tian C; Wang M; Han Z; Fang F; Zhang Z; Wang X; Liu J, 2017, 'Design, synthesis and biological evaluation of novel 6-substituted pyrrolo [3,2-d] pyrimidine analogues as antifolate antitumor agents', European Journal of Medicinal Chemistry, 138, pp. 630 - 643, http://dx.doi.org/10.1016/j.ejmech.2017.07.002
    Journal articles | 2016
    Li Y; Han Z; Tian C; Zhang Z; Liu J, 2016, 'Design, synthesis and evaluation of novel non-ATP competitive CHK1 inhibitors as chemotherapy sensitizing agents', Journal of Chinese Pharmaceutical Sciences, 25, pp. 726 - 736, http://dx.doi.org/10.5246/jcps.2016.10.081

  • 2025 ECA Startup showcase First Place and People’s Choice Award, UNSW Founders
  • 2024 RSC Applied polymers Best Presentation Prize, Australian Centre of Nanomedicine
  • 2019 Scientia Scholarship for Higher Degree Research, The University of New South Wales
  • 2016 and 2017 National Academic Scholarship (second place), Peking University
  • 2013 Outstanding Medical Student Scholarship (third place), Peking University

My Research Supervision

Co-supervises 2 PhD and 2 master’s students with Prof Rona Chandrawati on sensor-related projects.