NSW-RPRN Service Pillar
The NSW-RPRN Services and Support Pillar is a network of world-class service facilities in genomics, proteomics, high-throughput screening, SARS-CoV-2 PC3 lab and animal testing and training facilities. This pillar enhances and supports other pillars and projects within the NSW-RNA Production and Research Network (NSW-RPRN).
The activities within the Services and Support Pillar will ensure the successful execution, quality and completion of all the key activities within the NSW-PPRN, paving the way for a stronger RNA manufacturing and research ecosystem in NSW.
Download the NSW-RPRN Capabilities presentation for more information on key support facilities.
Management and administration
UNSW is the lead institution and is the base for management and governance of the NSW-RPRN including activities such as reporting and outreach.
Key Contacts: Joshua Peterson, Catherine McDonald, Marjorie Fox-Owens.
Sequencing and Genomics
The Ramaciotti Centre for Genomics provides state-of-the-art sequencing services which are predominantly used to monitor mRNA quality and measure RNA-expression level relating to in vitro assays.
Key Contacts: Helena Mangs.
The Centre for Infectious Diseases & Microbiology at Westmead lab specialises in pathogen surveillance, including SARS-CoV-2, providing mRNA researchers with access to valuable data on these pathogens.
Key Contacts: Vitali Sintchenko, Rebeccca Rockett.
Proteomics
The Australian Proteome Analysis Facility (APAF) at Macquarie University offers research support services in protein analysis and characterisation, a vital tool in verifying mRNA expression in target organisms.
Key Contacts: Nicolle Packer, Belinda Schiller.
High throughput screening
The high-throughput screening capabilities located at the ANU Centre for Therapeutic Discovery allow NSW-RPRN to rapidly screen their products in cellular assays.
Key Contacts: Thomas Preiss, Amee George.
PC3 Labs
The Kirby Institute (UNSW) has the largest collection of SARS-CoV-2 variants in Australia, while the PC3 animal facility at the Centenary Institute (UTS) includes a unique respiratory mouse model. Both facilities are crucial for carrying out in vitro and in vivo SARS-CoV-2 efficacy studies.
Key Contacts: Stuart Turville, Philip Hansbro.
Training, GMP and Quality Control, and Clinical Support
Training and advice on matters relating to GLP and GMP manufacturing are supported by the Biologics Innovation Facility at UTS and the Recombinant Product Facility at UNSW.
Support on quality control processes, clinical developmental pathways includes vaccine experts at the Kirby Institute and the Westmead Institute of Medical Research, together with cell therapy GMP experts at Cell and Molecular Therapies (Royal Prince Alfred Hospital).
Key Contacts: Sharon Sagnella, David Rickards, Tony Cunningham, John Rasko, Tony Kelleher, Chris Marquis.
