Branching Lung Organoids

Lung organoids with branching of proximal and distal airway-like structures
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Description

Branching Lung Organoids are 3D structures derived from stem cells and used to study lung development and disease in vitro.

Our organoids are generated in-house using a robust, reproducible kit from STEMCell Technologies and can be further used by researchers to model infectious diseases (e.g., covid, RSV and measles) and other lung diseases, as well as being used to screen and test therapeutics.

Specifications

    • Pluripotent stem cell derived 
    • Grown at the air liquid interface 
    • Available in 24-well transwells 
    • Cultured as a minimum of 12 organoids 
    • Culture time (min. 28d) 
    • Can be maintained for >3 months
    • Definitive Endoderm 
    • Anterior Foregut Endoderm 
    • Lung Bud Organoids 
    • Branching Lung Organoid
    • EPCAM 
    • NKX2.1 
    • SOX2/SOX9 
    • MUC1/MUC5A 
    • P63 
    • Mature Lung Markers (SFTPC, SFTPB and ABCA3)

Applications

  • Stem Cell Biology 
  • 3D Culture 
  • Organoids 
  • Drug Screening 
  • Lung Biology 
  • Lung disease modelling 
  • Regenerative medicine 
  • Viral infection research

Instrument location

3D Culture Facility

Room 2061, Level 2
BioSciences (E26)
UNSW Sydney, NSW 2033
In 3D Culture Facility

Phone: 02 9348 8212
Email: 3Dculture@unsw.edu.au

Dr Alison Ferguson

Research Manager
  • Phone icon
    Phone
    02 9348 8212
  • Send email envelope icon
    Email
    alison.ferguson@unsw.edu.au

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