Patient-derived Airway Cultures
Airway models derived from explants of primary cells grown at the air-liquid interface (ALI)
Description
Patient-derived ALI cultures generated using commercially available Normal Human Bronchial Epithelial (NHBE) are ideal for studying airway diseases, respiratory biology, and drug testing, offering a patient-specific approach for exploring lung pathophysiology and developing targeted therapies.
Specifications
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- Cultured from patient-derived explants or primary tissue samples
- Grown at the air-liquid interface (ALI) to promote the development of stratified epithelial layers with functional cilia
- Available in both fresh and fixed forms, depending on sample and research needs
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- Epithelial cells (EpCAM)
- Mucin (e.g., MUC5AC)
- Basal and progenitor cell markers
- Acetylated tubulin (ciliary marker)
Applications
- 3D Culture
- Lung Biology
- Lung disease modelling
- Personalised Medicine
- Drug screening
- Infectious research
- Ciliary dysfunction
- Regenerative medicine
Instrument location
3D Culture Facility
Room 2061, Level 2
BioSciences (E26)
UNSW Sydney, NSW 2033
Phone: 02 9348 8212
Email: 3Dculture@unsw.edu.au
Dr Alison Ferguson
Research Manager
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Phone
02 9348 8212 -
Email
alison.ferguson@unsw.edu.au
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