Thermo Orbitrap Fusion Lumos 

The Orbitrap Fusion Lumos features a Tribrid design, advanced software, and enhanced sensitivity for versatile experiments.
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Bioanalytical Mass Spectrometry Facility

Description

The Orbitrap Fusion Lumos includes an exclusive Tribrid design incorporating 3 different mass analysers (a quadrupole, an ion trap and an Orbitrap), enabling a large number of different experiments to be performed with a single mass spectrometer.  Software developments have also simplified the set-up of complex experiments.  

Other significant technological advances including a brighter ion source and improved vacuum/pumping.  Additional enhancements of the Lumos include greater scan speed, high mass resolving power, sensitivity and an improved ETD capability and EThcD fragmentation.  These attributes make available a versatile system that makes detection of very low abundance proteins and lipids easier and more reproducible.

Specifications

    • Low flow liquid chromatography system
    • Flow rate range: 50 nL/min to 50 µL/min
    • Ion Source: Adjustable heated electrospray ionization (HESI) probe
    • Resolving power: Up to 500,000 FWHM at m/z 200.
    • Fragmentation Techniques: CID, HCD, and optional ETD and EThcD available at any stage of MSn.

Applications

  • Bottom-up proteomics
  • ETD (Electron Transfer Dissociation) experiments
  • Post-Translational Modification (PTM) studies
  • Lipidomics analyses

Instrument location

Bioanalytical Mass Spectrometry Facility

Room 401, Level 4 North West 
Wallace Wurth Building (C27) 
UNSW Sydney, NSW 2033

Phone: 02 9385 1717
Email: 
bmsf@unsw.edu.au

A/Prof Mark Raftery

Director of BMSF
  • Phone icon
    Phone
    02 9385 1892
  • Send email envelope icon
    Email
    m.raftery@unsw.edu.au

Dr Ling Zhong

Research Officer
  • Phone icon
    Phone
    02 9385 2717
  • Send email envelope icon
    Email
    l.zhong@unsw.edu.au

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