Thermo TSQ Vantage
Description
The TSQ Vantage is a high-performance triple stage quadrupole mass spectrometer and is used predominately for selected reaction monitoring (SRM) experiments. It includes a syringe pump, a divert/inject valve, an atmospheric pressure ionisation (API) source, and the Xcalibur™ data system.
The mass spectrometer can be operated in electrospray ionisation (ESI), atmospheric pressure chemical ionisation (APCI) and Atmospheric Pressure Photo ionisation (APPI) modes. Like ESI, APCI and APPI are soft ionization techniques.
With ESI, the TSQ Vantage can quantitively analyse hundreds of compounds within a single UPLC run and is especially useful for quantitative analysis of polar compounds, which include biological analytes, pharmaceuticals and their metabolites. APCI provides molecular weight information for compounds of low polarity that are somewhat volatile. APCI is typically used to analyse small molecules with molecular weights up to about 1000 amu.
Specifications
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- Maximum Pressure: Up to 1500 bar (21,750 psi)
- Flow Range: 1 nL/min to 100 μL/min
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- Mass Range: 10-1500 m/z
- Resolution: 7500 (FWHM) at m/z 508 of polytyrosine, adjustable to better than 0.1 Da peak width (FWHM) across the entire mass range
Applications
- Small molecule analysis
- Metabolite profiling
Instrument location
Bioanalytical Mass Spectrometry Facility
Room 2012, Level 2 South
Biosciences Precinct (E26)
UNSW Sydney, NSW 2033
BMSF
Phone: 02 9385 1717
Email: bmsf@unsw.edu.au
Ms Sonia Bustamante
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Phone
02 9385 1613 -
Email
s.bustamante@unsw.edu.au
Dr Chowdhury Sarowar
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Phone
02 9348 1699 -
Email
c.h.sarowar@unsw.edu.au
Dr Andrew Jenner
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Phone
02 9385 7649 -
Email
andrew.jenner@unsw.edu.au
Parent facility
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