Thermo TSQ Altis Plus
Description
The Altis Plus is a high-performance triple stage quadrupole mass spectrometer and is used predominately for selected reaction monitoring (SRM) experiments. It includes a syringe pump, a divert/inject valve, an atmospheric pressure ionisation (API) source, and the Xcalibur™ data system.
The mass spectrometer can be operated in electrospray ionisation (ESI), atmospheric pressure chemical ionisation (APCI) and Atmospheric Pressure Photo ionisation (APPI) modes. Like ESI, APCI and APPI are soft ionization techniques.
With ESI, the Altis Plus can quantitively analyse hundreds of compounds within a single UPLC run and is especially useful for quantitative analysis of polar compounds, which include biological analytes, pharmaceuticals and their metabolites. APCI provides molecular weight information for compounds of low polarity that are somewhat volatile. APCI is typically used to analyse small molecules with molecular weights up to about 1000 amu.
Specifications
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- Maximum Pressure: Up to 1500 bar (21,750 psi)
- Flow Range: 1 nL/min to 100 μL/min
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- Mass Range: 2 to 2010 m/z
- Resolving Power: High-resolution selected-reaction monitoring (H-SRM) with 0.2 Da FWHM
- Scan Speed: Ultrafast selected-reaction monitoring (SRM) with acquisition speeds up to 600 SRM transitions per second
Applications
- Small molecule analysis
- Metabolite profiling
- Lipid measurements
Instrument location
Bioanalytical Mass Spectrometry Facility
Room 401, Level 4 North West
Wallace Wurth Building (C27)
UNSW Sydney, NSW 2033
Phone: 02 9385 1717
Email: bmsf@unsw.edu.au
Room 2012, Level 2 South
Biosciences Precinct (E26)
UNSW Sydney, NSW 2033
Phone: 02 9385 1717
Email: bmsf@unsw.edu.au
Ms Sonia Bustamante
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Phone
02 9385 1613 -
Email
s.bustamante@unsw.edu.au
Dr Russell Pickford
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Phone
02 9385 2952 -
Mobile
410 761 718 -
Email
r.pickford@unsw.edu.au
Dr Andrew Jenner
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Phone
02 9385 7649 -
Email
andrew.jenner@unsw.edu.au
Parent facility
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