Cryo-TEM – Thermo Fisher Scientific Talos Arctica
Description
The Thermo Fisher Scientific Talos Arctica is a 200kV field emission Cryo-Transmission Electron Microscope (Cryo-TEM) managed in partnership with the Victor Chang Cardiac Research Institute.
This powerful, stable, and versatile system excels in delivering high-resolution 3D characterization of biological and biomaterial samples. It is particularly ideal for researchers in cell biology, structural biology, and nanotechnology. The Talos Arctica features advanced automation and high-throughput capabilities, including robotic sample handling and automated loading for up to 12 samples, enhancing data acquisition speed and efficiency. Additionally, it is sophisticated software suite supports a wide range of applications, from single-particle analysis to tomography, making it an inviable tool for researchers aiming to achieve detailed insights into the structure and function of complex biological systems.
Specifications
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- Electron Gun: X-FEG
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- Resolution: <0.23nm
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- Autoloader: automated loading of 12 grids
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- Camera: 4k x 4k Falcon 3EC direct electron detector 4k x 4k CETA CCD
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- Phase Plate: Volta Phase Plate
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- Tilting angle: -70o to +70o
Publishing Microscopy Data Acquired on the ThermoFisher Scientific Talos Arctica
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- Nanoparticle Drop-casting
- Chemical fixation, dehydration, critical point drying
- Mounting in resin
- Staining
- Ultramicrotomy
- TEM Grid details
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- Manufacturer: FEI
- Model: Tecnai T20
- Type: LaB6
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- Accelerating voltage (200 kV)
- Detector(s) used for imaging (CMOS Camera, HAADF-STEM)
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- Adjustments to contrast/brightness
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- Scalebars can be added or removed from images in the export options.
Acknowledgement:
“The authors acknowledge the facilities and the scientific and technical assistance of Microscopy Australia at the Electron Microscope Unit (EMU) within the Mark Wainwright Analytical Centre (MWAC) at UNSW Sydney.”
Credit EMU staff: Feel free to mention EMU staff who have assisted you with your work! If staff have been involved with your work beyond basic training and support (e.g., project design, complex data/image processing, independent imaging/analysis, manuscript preparation), it may be appropriate to discuss co-authorship with the relevant staff and your supervisor.
Don’t forget to email the EMU lab manager with a copy of your publication to claim 2 hours of free microscopy time.
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Applications
- Life Science
- Medical science
- Pharmaceutical industry
- Biomaterials
- Solar and battery materials
- Earth Science
- Materials Science
Capabilities
- Low Dose Imaging
- Automatic cryo
- EM acquisition for Single Particle Analysis
- Batch cryo-electron Tomography (cryo-ET)
- Microcrystal Electron Diffraction
Funding partners
Instrument location
Electron Microscope Unit
B22b, Basement
Hilmer Building (E10)
UNSW Sydney, NSW 2033
Access – To discuss training or how your project could benefit from using this microscope, please contact the EMU using the enquiries form or email EMUAdmin@unsw.edu.au
Dr Juanfang Ruan
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Email
juanfang.ruan@unsw.edu.au
Dr Daniel Luque
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Email
d.luque@unsw.edu.au
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