Associate Professor Andrew   Moorhouse
Associate Professor

Associate Professor Andrew Moorhouse

Medicine & Health
Physiology

Research Interests:
Dr Moorhouse's broad interest are in the molecular and cellular basis of neuronal excitability, focusing on electrical and chemical signaling in nerve cells and glia contribute to neural circuit activity in health and disease . He leads the Neurobiology Research Lab that aims to develop improved and novel strategies to treat different brain disorders by gaining greater understanding of underlying cellular mechanisms. In collaboration with colleagues at UNSW and Japan, we use a range of techniques, including electrophysiology, cell culture, live cell imaging, biochemical and histological approaches and behavioural analysis. Dr Moorhouse and his colleagues have published over 50 journal articles in this area with over 3500 citations.  Dr Moorhouse's current research focus is on; i) the role of KCC2 transporter in Cl- homeostasis and neuronal inhibition in health and disease;  ii) the molecular basis of ion permeation in GABA and glycine receptors, and iii) functions of microglia and astrocytes in neural circuit plasticity 

Broad Research Areas:
Neuroscience, Cell Physiology, Ion Channels, Membrane Transport Proteins, Glia. 

Qualifications:
BSc, PhD Syd

Society Memberships & Professional Activities:
Dr Moorhouse is a regular member of the Australian Neuroscience Society (ANS) and the Australian Physiological Society (AuPS).  He regularly reviews grants and research papers for a variety of National and International funding bodies (e.g., NH&MRC, ARC, Wellcome Trust) and scientific journals (e.g., Neuropharmacology, Pain, Journal of Physiology, British Journal of Pharmacology) and is on the editorial review board of the Journal of Biological Chemistry.

Specific Research Keywords:
Membrane Transporters, Ion Channels, Electrophysiology, Synapse Function and Plasticity, Neuronal Inhibition, GABA receptors, Microglia.

Phone
+61 2 9385 2575
Location
Cellular and Systems Physiology, Department of Physiology, School of Medical Sciences, Rm 302, Level 3 NW, Wallace Wurth Bldg

Publications

  • Book Chapters | 2019
    Associate Professor Andrew Moorhouse
    Wake H; Horiuchi H; Kato D; Moorhouse AJ; Nabekura J, 2019, 'Physiological Implications of Microglia–Synapse Interactions', in Methods in Molecular Biology, United States, pp. 69 - 80, http://dx.doi.org/10.1007/978-1-4939-9658-2_6
    Book Chapters | 2019
    Associate Professor Andrew Moorhouse
    Kato D; Ikegami A; Horiuchi H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'In Vivo Two-Photon Imaging of Microglial Synapse Contacts', in Methods in Molecular Biology, United States, pp. 281 - 286, http://dx.doi.org/10.1007/978-1-4939-9658-2_20
    Book Chapters | 2016
    Associate Professor Andrew Moorhouse
    Moorhouse AJ, 2016, 'Membrane Potential: Concepts', in Encyclopedia of Cell Biology, pp. 218 - 236, http://dx.doi.org/10.1016/B978-0-12-394447-4.10027-6
    Book Chapters | 2015
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Lewis TM; Barry PH, 2015, 'Analyzing Ion Permeation in Channels and Pumps Using Patch-Clamp Recording', in Clarke RJ; Khalid MAA (ed.), Pumps, Channels and Transporters Methods of Functional Analysis, John Wiley & Sons, Hoboken, New Jersey, pp. 51 - 88, http://dx.doi.org/10.1002/9781119085126.ch3
    Book Chapters | 2012
    Associate Professor Andrew Moorhouse
    Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Springer Protocols Handbooks, Springer Japan, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3_4
    Book Chapters | 2012
    Associate Professor Andrew Moorhouse
    Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Okada Y (ed.), Patch Clamp Techniques: From Beginning to Advanced Protocols, edn. 1st, Springer, Tokyo, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3
    Book Chapters | 2011
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Nabekura J, 2011, 'Cellular Mechanisms of neuronal Homeostasis and its Modulation by Neuronal Injury', in Woodin MA; Maffei A (ed.), Inhibitory Synaptic Plasticity, Springer, New York, pp. 123 - 134, http://dx.doi.org/10.1007/978-1-4419-6978-1_9
    Book Chapters | 2008
    Associate Professor Andrew Moorhouse
    Barry PH; Qu W; Moorhouse AJ, 2008, 'Biophysics of CNG Ion Channels', in Martinac B (ed.), Sensing with Ion Channels, edn. Original, Springer, Berlin Heidelberg, pp. 175 - 200
    Book Chapters | 2019
    Associate Professor Andrew Moorhouse
    Kato D; Ikegami A; Horiuchi H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'In Vivo Two-Photon Imaging of Microglial Synapse Contacts', in Methods in Molecular Biology, United States, pp. 281 - 286, http://dx.doi.org/10.1007/978-1-4939-9658-2_20
    Book Chapters | 2019
    Associate Professor Andrew Moorhouse
    Wake H; Horiuchi H; Kato D; Moorhouse AJ; Nabekura J, 2019, 'Physiological Implications of Microglia–Synapse Interactions', in Methods in Molecular Biology, United States, pp. 69 - 80, http://dx.doi.org/10.1007/978-1-4939-9658-2_6
    Book Chapters | 2016
    Associate Professor Andrew Moorhouse
    Moorhouse AJ, 2016, 'Membrane Potential: Concepts', in Encyclopedia of Cell Biology, pp. 218 - 236, http://dx.doi.org/10.1016/B978-0-12-394447-4.10027-6
    Book Chapters | 2015
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Lewis TM; Barry PH, 2015, 'Analyzing Ion Permeation in Channels and Pumps Using Patch-Clamp Recording', in Clarke RJ; Khalid MAA (ed.), Pumps, Channels and Transporters Methods of Functional Analysis, John Wiley & Sons, Hoboken, New Jersey, pp. 51 - 88, http://dx.doi.org/10.1002/9781119085126.ch3
    Book Chapters | 2012
    Associate Professor Andrew Moorhouse
    Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Springer Protocols Handbooks, Springer Japan, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3_4
    Book Chapters | 2012
    Associate Professor Andrew Moorhouse
    Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Okada Y (ed.), Patch Clamp Techniques: From Beginning to Advanced Protocols, edn. 1st, Springer, Tokyo, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3
    Book Chapters | 2011
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Nabekura J, 2011, 'Cellular Mechanisms of neuronal Homeostasis and its Modulation by Neuronal Injury', in Woodin MA; Maffei A (ed.), Inhibitory Synaptic Plasticity, Springer, New York, pp. 123 - 134, http://dx.doi.org/10.1007/978-1-4419-6978-1_9
    Book Chapters | 2008
    Associate Professor Andrew Moorhouse
    Barry PH; Qu W; Moorhouse AJ, 2008, 'Biophysics of CNG Ion Channels', in Martinac B (ed.), Sensing with Ion Channels, edn. Original, Springer, Berlin Heidelberg, pp. 175 - 200
  • Journal articles | 2021
    Associate Professor Andrew Moorhouse
    Okada T; Kato D; Nomura Y; Obata N; Quan X; Morinaga A; Yano H; Guo Z; Aoyama Y; Tachibana Y; Moorhouse AJ; Matoba O; Takiguchi T; Mizobuchi S; Wake H, 2021, 'Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target', Science Advances, vol. 7, http://dx.doi.org/10.1126/sciadv.abd8261
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Ozaki K; Kato D; Ikegami A; Hashimoto A; Sugio S; Guo Z; Shibushita M; Tatematsu T; Haruwaka K; Moorhouse AJ; Yamada H; Wake H, 2020, 'Maternal immune activation induces sustained changes in fetal microglia motility', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-020-78294-2
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Kato D; Wake H; Lee PR; Tachibana Y; Ono R; Sugio S; Tsuji Y; Tanaka YH; Tanaka YR; Masamizu Y; Hira R; Moorhouse AJ; Tamamaki N; Ikenaka K; Matsukawa N; Fields RD; Nabekura J; Matsuzaki M, 2020, 'Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity', GLIA, vol. 68, pp. 193 - 210, http://dx.doi.org/10.1002/glia.23713
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Karunanithi S; Lin YQ; Lorenzo Odierna G; Menon H; Gonzalez JM; Gregory Neely G; Noakes PG; Lavidis NA; Moorhouse AJ; van Swinderen B, 2020, 'Activity-dependent global downscaling of evoked neurotransmitter release across glutamatergic inputs in Drosophila', Journal of Neuroscience, vol. 40, pp. 8025 - 8041, http://dx.doi.org/10.1523/JNEUROSCI.0349-20.2020
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Haruwaka K; Ikegami A; Tachibana Y; Ohno N; Konishi H; Hashimoto A; Matsumoto M; Kato D; Ono R; Kiyama H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'Dual microglia effects on blood brain barrier permeability induced by systemic inflammation', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-13812-z
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Nakamura K; Moorhouse AJ; Cheung DL; Eto K; Takeda I; Rozenbroek PW; Nabekura J, 2019, 'Overexpression of neuronal K + –Cl co-transporter enhances dendritic spine plasticity and motor learning', Journal of Physiological Sciences, vol. 69, pp. 453 - 463, http://dx.doi.org/10.1007/s12576-018-00654-5
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Power JM, 2019, 'Making light work of fine-tuning channelrhodopsins', Journal of Biological Chemistry, vol. 294, pp. 3822 - 3823, http://dx.doi.org/10.1074/jbc.H119.007749
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Gorlamandala N; Parmar J; Craig AJ; Power JM; Moorhouse AJ; Krishnan AV; Housley GD, 2018, 'Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model', Translational Stroke Research, vol. 9, pp. 643 - 653, http://dx.doi.org/10.1007/s12975-018-0615-1
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Ishikawa T; Eto K; Kim SK; Wake H; Takeda I; Horiuchi H; Moorhouse AJ; Ishibashi H; Nabekura J, 2018, 'Cortical astrocytes prime the induction of spine plasticity and mirror image pain', Pain, vol. 159, pp. 1592 - 1606, http://dx.doi.org/10.1097/j.pain.0000000000001248
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Akiyoshi R; Wake H; Kato D; Horiuchi H; Ono R; Ikegami A; Haruwaka K; Omori T; Tachibana Y; Moorhouse AJ; Nabekura J, 2018, 'Microglia enhance synapse activity to promote local network synchronization', eNeuro, vol. 5, http://dx.doi.org/10.1523/ENEURO.0088-18.2018
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Goulton CS; Watanabe M; Cheung DL; Wang KW; Oba T; Khoshaba A; Lai D; Inada H; Eto K; Nakamura K; Power JM; Lewis TM; Housley GD; Wake H; Nabekura J; Moorhouse AJ, 2018, 'Conditional Upregulation of KCC2 selectively enhances neuronal inhibition during seizures', , http://dx.doi.org/10.1101/253831
    Journal articles | 2017
    Associate Professor Andrew Moorhouse
    Nakahata Y; Eto K; Murakoshi H; Watanabe M; Kuriu T; Hirata H; Moorhouse AJ; Ishibashi H; Nabekura J, 2017, 'Activation-dependent rapid postsynaptic clustering of glycine receptors in mature spinal cord neurons', eNeuro, vol. 4, http://dx.doi.org/10.1523/ENEURO.0194-16.2017
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Miyamoto A; Wake H; Ishikawa AW; Eto K; Shibata K; Murakoshi H; Koizumi S; Moorhouse AJ; Yoshimura Y; Nabekura J, 2016, 'Microglia contact induces synapse formation in developing somatosensory cortex', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms12540
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Kim SK; Hayashi H; Ishikawa T; Shibata K; Shigetomi E; Shinozaki Y; Inada H; Roh SE; Kim SJ; Lee G; Bae H; Moorhouse AJ; Mikoshiba K; Fukazawa Y; Koizumi S; Nabekura J, 2016, 'Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain', Journal of Clinical Investigation, vol. 126, pp. 1983 - 1997, http://dx.doi.org/10.1172/JCI82859
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Kato G; Inada H; Wake H; Akiyoshi R; Miyamoto A; Eto K; Ishikawa T; Moorhouse AJ; Strassman AM; Nabekura J, 2016, 'Microglial contact prevents excess depolarization and rescues neurons from excitotoxicity', eNeuro, vol. 3, pp. 9133 - 9144, http://dx.doi.org/10.1523/ENEURO.0004-16.2016
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Miyamoto A; Wake H; Moorhouse AJ; Nabekura J, 2013, 'Microglia and synapse interactions: Fine tuning neural circuits and candidate molecules', Frontiers in Cellular Neuroscience, vol. 7, http://dx.doi.org/10.3389/fncel.2013.00070
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2013, 'An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology', European Biophysics Journal, vol. 42, pp. 631 - 646, http://dx.doi.org/10.1007/s00249-013-0911-3
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Miyamoto A; Nabekura J, 2013, 'Microglia: Actively surveying and shaping neuronal circuit structure and function', Trends in Neurosciences, vol. 36, pp. 209 - 217, http://dx.doi.org/10.1016/j.tins.2012.11.007
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Alexander SPH; Benson HE; Faccenda E; Pawson AJ; Sharman JL; McGrath JC; Catterall WA; Spedding M; Peters JA; Harmar AJ, 2013, 'THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: OVERVIEW', BRITISH JOURNAL OF PHARMACOLOGY, vol. 170, pp. 1449 - 1458, http://dx.doi.org/10.1111/bph.12444
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Eto K; Ishibashi H; Yoshimura T; Watanabe M; Miyamoto A; Ikenaka K; Moorhouse AJ; Nabekura J, 2012, 'Enhanced GABAergic activity in the mouse primary somatosensory cortex is insufficient to alleviate chronic pain behavior with reduced expression of neuronal potassium-chloride cotransporter', Journal of Neuroscience, vol. 32, pp. 16552 - 16559, http://dx.doi.org/10.1523/JNEUROSCI.2104-12.2012
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Kim YS; Wong AC; Power J; Tadros SF; Klugmann M; Moorhouse AJ; Bertrand PP; Housley GD, 2012, 'Alternative Splicing of the TRPC3 Ion Channel Calmodulin/ IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux', The Journal of Neuroscience, vol. 32, pp. 11414 - 11423, http://dx.doi.org/10.1523/JNEUROSCI.6446-11.2012
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Nabekura J, 2012, 'Functions of microglia in the central nervous system-beyond the immune response', Neuron Glia Biology, vol. 7, pp. 47 - 53, http://dx.doi.org/10.1017/S1740925X12000063
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Lewis TM; Moorhouse AJ, 2010, 'Further analysis of counterion permeation through anion-selective glycine receptor channels.', Channels, vol. 4, pp. 142 - 149, http://www.landesbioscience.com/journals/channels/article/11020
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ; Barry PH, 2010, 'External divalent cations increase anion-cation permeability ratio in glycine receptor channels', Pflugers Archiv - European Journal of Physiology, vol. 460, pp. 131 - 152, http://dx.doi.org/10.1007/s00424-010-0792-6
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Nakahata Y; Miyamoto A; Watanabe M; Moorhouse AJ; Nabekura J; Ishibashi H, 2010, 'Depolarizing shift in the GABA-induced current reversal potential by lidocaine hydrochloride', Brain Research, vol. 1345, pp. 19 - 27, http://dx.doi.org/10.1016/j.brainres.2010.05.052
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2009, 'Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals', Journal of Neuroscience, vol. 29, pp. 3974 - 3980, http://dx.doi.org/10.1523/JNEUROSCI.4363-08.2009
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Watanabe M; Wake H; Moorhouse AJ; Nabekura J, 2009, 'Clustering of Neuronal K+-Cl- Cotransporters in Lipid Raftsby Tyrosine Phosphorylation', The Journal of Biological Chemistry, vol. 284, pp. 27980 - 27988, http://dx.doi.org/10.1074/jbc.M109.043620
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Carland JE; cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Peters JA; Lambert J; Moorhouse AJ, 2009, 'Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels', The Journal of Biological Chemistry, vol. 284, pp. 2023 - 2030, http://dx.doi.org/10.1074/jbc.M806618200
    Journal articles | 2008
    Associate Professor Andrew Moorhouse
    Sugiharto S; Lewis TM; Moorhouse AJ; Schofield PR; Barry PH, 2008, 'Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels', Biophysical Journal, vol. 95, pp. 4698 - 4715, http://dx.doi.org/10.1529/biophysj.107.125690
    Journal articles | 2008
    Associate Professor Andrew Moorhouse
    Park E; Choi I; Cho J; Nakamura M; Lee J; Lee M; Choi B; Moorhouse AJ; Jang I, 2008, 'Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons', Life Sciences, vol. 83, pp. 149 - 154, http://dx.doi.org/10.1016/j.lfs.2008.04.024
    Journal articles | 2007
    Associate Professor Andrew Moorhouse
    Wake H; Watanabe M; Moorhouse AJ; Kanematsu T; Horibe S; Matsukawa N; Asai K; Ojika K; Hirata M; Nabekura J, 2007, 'Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation', Journal of Neuroscience, vol. 27, pp. 1642 - 1650, http://dx.doi.org/10.1523/JNEUROSCI.3104-06.2007
    Journal articles | 2006
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Chandra M; Pierce KD; Lewis TM; Barry PH, 2006, 'A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel', Journal of General Physiology, vol. 127, pp. 375 - 389, http://dx.doi.org/10.1085/jgp.200509378
    Journal articles | 2005
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Lewis TM; Pierce KD; Barry PH, 2005, 'Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel', European Biophysics Journal with Biophysics Letters, vol. 34, pp. 442 - 453, http://dx.doi.org/10.1007/s00249-005-0479-7
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Katsurabayashi S; Kubota H; Moorhouse AJ; Akaike N, 2004, 'Differential modulation of evoked and spontaneous glycine release fromrat spinal cord glycinergic terminals by the cyclic AMP/protein kinaseA transduction cascade', Journal of Neurochemistry, vol. 91, pp. 657 - 666, http://dx.doi.org/10.1111/j.1471-4159.2004.02741.x
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2004, 'Ligand-gated ion channels: mechanisms underlying ion selectivity', Progress in Biophysics and Molecular Biology, vol. 86, pp. 161 - 204, http://dx.doi.org/10.1016/j.pbiomolbio.2003.09.002
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Li S; Vickery RM; Hill MA; Morley JW, 2004, 'A patch-clamp investigation of membrane currents in a novel mammalian retinal ganglion cell line', Brain Research, vol. 1003, pp. 205 - 208, http://dx.doi.org/10.1016/j.brainres.2004.01.027
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Carland JE; Moorhouse AJ; Barry PH; Johnston G; Chebib M, 2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, vol. 279, pp. 54153 - 54160, http://dx.doi.org/10.1074/jbc.M410625200
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', The Journal of Physiology, vol. 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Jeong H; Jan I; Moorhouse AJ; Akaike N, 2003, 'Activation of presynaptic glycine receptors facilitate glycine release from presynaptic terminals synapsing onto rat spinal sacral dorsal commissural nucleus nerons', The Journal of Physiology, vol. 550, pp. 373 - 383, http://dx.doi.org/10.1113/jphysiol.2003.041053
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Akaike N; Moorhouse AJ, 2003, 'Techniques: Applications of the Nerve - bouton preparation in Neuropharmacology', Trends in Pharmacological Sciences, vol. 24, pp. 44 - 47, http://dx.doi.org/10.1016/S0165-6147(02)00010-X
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Lee DJ; Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2003, 'The contribution of P250 (P-2`D) to ion selectivity and pore diameter in the human glycine receptor.', Neuroscience Letters, vol. 351, pp. 196 - 200, http://dx.doi.org/10.1016/j.neulet.2003.08.005
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', Journal of Physiology, vol. 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524
    Journal articles | 2002
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; Pierce K; Schofield PR; Barry PH, 2002, 'Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion charge selectivity', Journal of General Physiology, vol. 119, pp. 393 - 410, http://dx.doi.org/10.1085/jgp.20028552
    Journal articles | 2002
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Keramidas A; Zaikine A; Zaykin A; Schofield PR; Barry PH, 2002, 'Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels', Journal of General Physiology, vol. 119, pp. 411 - 425, http://dx.doi.org/10.1085/jgp.20028553
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Kaur R; Zhu XO; Moorhouse AJ; Barry PH, 2001, 'Ip3-gated channels and their occurrence relative to CNG channels in the soma and dendritic knob of rat olfactory receptor neurons', Journal of Membrane Biology, vol. 181, pp. 91 - 105, http://dx.doi.org/10.1007/s00232-001-0013-5
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Kaur R; Zhu X; Moorhouse AJ; Barry PH, 2001, 'IP3-Gated Channels and their Occurrence Relative to CNG Channels in the Soma and Dendritic Knob of Rat Olfactory Receptor Neurons', Journal of Membrane Biology, vol. 181, pp. 91 - 105, https://www.ncbi.nlm.nih.gov/pubmed/11420596
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Anomalous Mole-Fraction Effects in Recombinat & Native Cyclic Nucleotide-Gated Channels in Rat Olfactory Receptor Neurons', Proceedings of the Royal Society of London Series B - Biological Sciences, vol. 268, pp. 1395 - 1403, http://dx.doi.org/10.1098/rspb.2001.1663
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; French C; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion to cation selective', Biophysical Journal, vol. 78, pp. 247 - 259, http://dx.doi.org/10.1016/S0006-3495(00)76287-4
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Rajendra S; Barry PH, 2000, 'Very negative potential for half-inactivation of and effects of anions on voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons', Journal of Membrane Biology, vol. 175, pp. 123 - 138, http://dx.doi.org/10.1007/s002320001061
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Qu W; Zhu X; Moorhouse AJ; Bieri S; Cunningham AM, 2000, 'Ion permeation and selectivity of wild-type recombinant rat (CNG (rOCNC1) chanels expressed in HEK293 cells', Journal of Membrane Biology, vol. 178, pp. 137 - 150, http://dx.doi.org/10.1007/s002320010021
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; French CD; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective', Biophysical Journal, pp. 247 - 259
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Smith PR; Proks P; Moorhouse AJ, 1999, 'Direct effects of tolutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic beta-cells', Pflugers Archiv - European Journal of Physiology, vol. 437, pp. 577 - 588, http://dx.doi.org/10.1007/s004240050820
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Keramidas A; Kuhlmann L; Moorhouse AJ; Barry PH, 1999, 'Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA2-and EGTA3-) for use in electrophysiological experiments', Journal of Neuroscience Methods, vol. 89, pp. 41 - 47, http://dx.doi.org/10.1016/S0165-0270(99)00036-9
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Jacques P; Barry PH; Schofield PR, 1999, 'The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating', Molecular Pharmacology, vol. 55, pp. 386 - 395, http://dx.doi.org/10.1124/mol.55.2.386
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why', Clinical and Experimental Pharmacology and Physiology, vol. 26, pp. 935 - 936, http://dx.doi.org/10.1046/j.1440-1681.1999.03149.x
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why?', Clinical and Experimental Pharmacology and Physiology, pp. 935 - 936
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Ammala C; Moorhouse AJ; Ashcroft FM, 1996, 'The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying Kir6.1 expressed in human embroyonic kidney cells', The Journal of Physiology, vol. 494, pp. 709 - 714, http://dx.doi.org/10.1113/jphysiol.1996.sp021526
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Ämmälä C; Moorhouse A; Gribble F; Ashfield R; Proks P; Smith PA; Sakura H; Coles B; Ashcroft SJH; Ashcroft FM, 1996, 'Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels', Nature, vol. 379, pp. 545 - 548, http://dx.doi.org/10.1038/379545a0
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Tucker SJ; Pessia M; Moorhouse AJ; Gribble F; Ashcroft FM; Maylie J; Adelman JP, 1996, 'Heteromeric channel formation and Ca2+-free media reduce the toxic effect of the weaver K 3.2 allele', FEBS Letters, vol. 390, pp. 253 - 257, http://dx.doi.org/10.1016/0014-5793(96)00635-7
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Proks P; Moorhouse A; Smith PA; Ashcroft FM, 1996, 'Protein kinase C does not influence the tolbutamide sensitivity of K-ATP currents', DIABETOLOGIA, vol. 39, pp. 105 - 105, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VA49300106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1995
    Associate Professor Andrew Moorhouse
    MOORHOUSE AJ; SPENCE I, 1995, 'SYNAPTIC TRANSMISSION, HYPOXIA AND ADENOSINE IN THE ISOLATED NEONATAL RAT SPINAL-CORD', JOURNAL OF PHYSIOLOGY-LONDON, vol. 489P, pp. P23 - P23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TH85400029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles |
    Associate Professor Andrew Moorhouse
    Takeda I; Yoshihara K; Cheung D; Agetsuma M; Tsuda M; Eto K; Moorhouse A; Nabekura J, 'Controlled activation of cortical astrocytes can reverse neuropathic chronic pain', , http://dx.doi.org/10.21203/rs.3.rs-150434/v1
    Journal articles | 2021
    Associate Professor Andrew Moorhouse
    Okada T; Kato D; Nomura Y; Obata N; Quan X; Morinaga A; Yano H; Guo Z; Aoyama Y; Tachibana Y; Moorhouse AJ; Matoba O; Takiguchi T; Mizobuchi S; Wake H, 2021, 'Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target', Science Advances, vol. 7, http://dx.doi.org/10.1126/sciadv.abd8261
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Ozaki K; Kato D; Ikegami A; Hashimoto A; Sugio S; Guo Z; Shibushita M; Tatematsu T; Haruwaka K; Moorhouse AJ; Yamada H; Wake H, 2020, 'Maternal immune activation induces sustained changes in fetal microglia motility', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-020-78294-2
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Karunanithi S; Lin YQ; Lorenzo Odierna G; Menon H; Gonzalez JM; Gregory Neely G; Noakes PG; Lavidis NA; Moorhouse AJ; van Swinderen B, 2020, 'Activity-dependent global downscaling of evoked neurotransmitter release across glutamatergic inputs in Drosophila', Journal of Neuroscience, vol. 40, pp. 8025 - 8041, http://dx.doi.org/10.1523/JNEUROSCI.0349-20.2020
    Journal articles | 2020
    Associate Professor Andrew Moorhouse
    Kato D; Wake H; Lee PR; Tachibana Y; Ono R; Sugio S; Tsuji Y; Tanaka YH; Tanaka YR; Masamizu Y; Hira R; Moorhouse AJ; Tamamaki N; Ikenaka K; Matsukawa N; Fields RD; Nabekura J; Matsuzaki M, 2020, 'Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity', GLIA, vol. 68, pp. 193 - 210, http://dx.doi.org/10.1002/glia.23713
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Haruwaka K; Ikegami A; Tachibana Y; Ohno N; Konishi H; Hashimoto A; Matsumoto M; Kato D; Ono R; Kiyama H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'Dual microglia effects on blood brain barrier permeability induced by systemic inflammation', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-13812-z
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Nakamura K; Moorhouse AJ; Cheung DL; Eto K; Takeda I; Rozenbroek PW; Nabekura J, 2019, 'Overexpression of neuronal K + –Cl co-transporter enhances dendritic spine plasticity and motor learning', Journal of Physiological Sciences, vol. 69, pp. 453 - 463, http://dx.doi.org/10.1007/s12576-018-00654-5
    Journal articles | 2019
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Power JM, 2019, 'Making light work of fine-tuning channelrhodopsins', Journal of Biological Chemistry, vol. 294, pp. 3822 - 3823, http://dx.doi.org/10.1074/jbc.H119.007749
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Gorlamandala N; Parmar J; Craig AJ; Power JM; Moorhouse AJ; Krishnan AV; Housley GD, 2018, 'Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model', Translational Stroke Research, vol. 9, pp. 643 - 653, http://dx.doi.org/10.1007/s12975-018-0615-1
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Akiyoshi R; Wake H; Kato D; Horiuchi H; Ono R; Ikegami A; Haruwaka K; Omori T; Tachibana Y; Moorhouse AJ; Nabekura J, 2018, 'Microglia enhance synapse activity to promote local network synchronization', eNeuro, vol. 5, http://dx.doi.org/10.1523/ENEURO.0088-18.2018
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Ishikawa T; Eto K; Kim SK; Wake H; Takeda I; Horiuchi H; Moorhouse AJ; Ishibashi H; Nabekura J, 2018, 'Cortical astrocytes prime the induction of spine plasticity and mirror image pain', Pain, vol. 159, pp. 1592 - 1606, http://dx.doi.org/10.1097/j.pain.0000000000001248
    Journal articles | 2018
    Associate Professor Andrew Moorhouse
    Goulton CS; Watanabe M; Cheung DL; Wang KW; Oba T; Khoshaba A; Lai D; Inada H; Eto K; Nakamura K; Power JM; Lewis TM; Housley GD; Wake H; Nabekura J; Moorhouse AJ, 2018, 'Conditional Upregulation of KCC2 selectively enhances neuronal inhibition during seizures', , http://dx.doi.org/10.1101/253831
    Journal articles | 2017
    Associate Professor Andrew Moorhouse
    Nakahata Y; Eto K; Murakoshi H; Watanabe M; Kuriu T; Hirata H; Moorhouse AJ; Ishibashi H; Nabekura J, 2017, 'Activation-dependent rapid postsynaptic clustering of glycine receptors in mature spinal cord neurons', eNeuro, vol. 4, http://dx.doi.org/10.1523/ENEURO.0194-16.2017
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Kato G; Inada H; Wake H; Akiyoshi R; Miyamoto A; Eto K; Ishikawa T; Moorhouse AJ; Strassman AM; Nabekura J, 2016, 'Microglial contact prevents excess depolarization and rescues neurons from excitotoxicity', eNeuro, vol. 3, pp. 9133 - 9144, http://dx.doi.org/10.1523/ENEURO.0004-16.2016
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Miyamoto A; Wake H; Ishikawa AW; Eto K; Shibata K; Murakoshi H; Koizumi S; Moorhouse AJ; Yoshimura Y; Nabekura J, 2016, 'Microglia contact induces synapse formation in developing somatosensory cortex', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms12540
    Journal articles | 2016
    Associate Professor Andrew Moorhouse
    Kim SK; Hayashi H; Ishikawa T; Shibata K; Shigetomi E; Shinozaki Y; Inada H; Roh SE; Kim SJ; Lee G; Bae H; Moorhouse AJ; Mikoshiba K; Fukazawa Y; Koizumi S; Nabekura J, 2016, 'Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain', Journal of Clinical Investigation, vol. 126, pp. 1983 - 1997, http://dx.doi.org/10.1172/JCI82859
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Alexander SPH; Benson HE; Faccenda E; Pawson AJ; Sharman JL; McGrath JC; Catterall WA; Spedding M; Peters JA; Harmar AJ, 2013, 'THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: OVERVIEW', BRITISH JOURNAL OF PHARMACOLOGY, vol. 170, pp. 1449 - 1458, http://dx.doi.org/10.1111/bph.12444
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Miyamoto A; Wake H; Moorhouse AJ; Nabekura J, 2013, 'Microglia and synapse interactions: Fine tuning neural circuits and candidate molecules', Frontiers in Cellular Neuroscience, vol. 7, http://dx.doi.org/10.3389/fncel.2013.00070
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Miyamoto A; Nabekura J, 2013, 'Microglia: Actively surveying and shaping neuronal circuit structure and function', Trends in Neurosciences, vol. 36, pp. 209 - 217, http://dx.doi.org/10.1016/j.tins.2012.11.007
    Journal articles | 2013
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2013, 'An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology', European Biophysics Journal, vol. 42, pp. 631 - 646, http://dx.doi.org/10.1007/s00249-013-0911-3
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Kim YS; Wong AC; Power J; Tadros SF; Klugmann M; Moorhouse AJ; Bertrand PP; Housley GD, 2012, 'Alternative Splicing of the TRPC3 Ion Channel Calmodulin/ IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux', The Journal of Neuroscience, vol. 32, pp. 11414 - 11423, http://dx.doi.org/10.1523/JNEUROSCI.6446-11.2012
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Eto K; Ishibashi H; Yoshimura T; Watanabe M; Miyamoto A; Ikenaka K; Moorhouse AJ; Nabekura J, 2012, 'Enhanced GABAergic activity in the mouse primary somatosensory cortex is insufficient to alleviate chronic pain behavior with reduced expression of neuronal potassium-chloride cotransporter', Journal of Neuroscience, vol. 32, pp. 16552 - 16559, http://dx.doi.org/10.1523/JNEUROSCI.2104-12.2012
    Journal articles | 2012
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Nabekura J, 2012, 'Functions of microglia in the central nervous system-beyond the immune response', Neuron Glia Biology, vol. 7, pp. 47 - 53, http://dx.doi.org/10.1017/S1740925X12000063
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Nakahata Y; Miyamoto A; Watanabe M; Moorhouse AJ; Nabekura J; Ishibashi H, 2010, 'Depolarizing shift in the GABA-induced current reversal potential by lidocaine hydrochloride', Brain Research, vol. 1345, pp. 19 - 27, http://dx.doi.org/10.1016/j.brainres.2010.05.052
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Lewis TM; Moorhouse AJ, 2010, 'Further analysis of counterion permeation through anion-selective glycine receptor channels.', Channels, vol. 4, pp. 142 - 149, http://www.landesbioscience.com/journals/channels/article/11020
    Journal articles | 2010
    Associate Professor Andrew Moorhouse
    Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ; Barry PH, 2010, 'External divalent cations increase anion-cation permeability ratio in glycine receptor channels', Pflugers Archiv - European Journal of Physiology, vol. 460, pp. 131 - 152, http://dx.doi.org/10.1007/s00424-010-0792-6
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Carland JE; cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Peters JA; Lambert J; Moorhouse AJ, 2009, 'Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels', The Journal of Biological Chemistry, vol. 284, pp. 2023 - 2030, http://dx.doi.org/10.1074/jbc.M806618200
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2009, 'Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals', Journal of Neuroscience, vol. 29, pp. 3974 - 3980, http://dx.doi.org/10.1523/JNEUROSCI.4363-08.2009
    Journal articles | 2009
    Associate Professor Andrew Moorhouse
    Watanabe M; Wake H; Moorhouse AJ; Nabekura J, 2009, 'Clustering of Neuronal K+-Cl- Cotransporters in Lipid Raftsby Tyrosine Phosphorylation', The Journal of Biological Chemistry, vol. 284, pp. 27980 - 27988, http://dx.doi.org/10.1074/jbc.M109.043620
    Journal articles | 2008
    Associate Professor Andrew Moorhouse
    Sugiharto S; Lewis TM; Moorhouse AJ; Schofield PR; Barry PH, 2008, 'Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels', Biophysical Journal, vol. 95, pp. 4698 - 4715, http://dx.doi.org/10.1529/biophysj.107.125690
    Journal articles | 2008
    Associate Professor Andrew Moorhouse
    Park E; Choi I; Cho J; Nakamura M; Lee J; Lee M; Choi B; Moorhouse AJ; Jang I, 2008, 'Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons', Life Sciences, vol. 83, pp. 149 - 154, http://dx.doi.org/10.1016/j.lfs.2008.04.024
    Journal articles | 2007
    Associate Professor Andrew Moorhouse
    Wake H; Watanabe M; Moorhouse AJ; Kanematsu T; Horibe S; Matsukawa N; Asai K; Ojika K; Hirata M; Nabekura J, 2007, 'Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation', Journal of Neuroscience, vol. 27, pp. 1642 - 1650, http://dx.doi.org/10.1523/JNEUROSCI.3104-06.2007
    Journal articles | 2006
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Chandra M; Pierce KD; Lewis TM; Barry PH, 2006, 'A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel', Journal of General Physiology, vol. 127, pp. 375 - 389, http://dx.doi.org/10.1085/jgp.200509378
    Journal articles | 2005
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Lewis TM; Pierce KD; Barry PH, 2005, 'Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel', European Biophysics Journal with Biophysics Letters, vol. 34, pp. 442 - 453, http://dx.doi.org/10.1007/s00249-005-0479-7
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Li S; Vickery RM; Hill MA; Morley JW, 2004, 'A patch-clamp investigation of membrane currents in a novel mammalian retinal ganglion cell line', Brain Research, vol. 1003, pp. 205 - 208, http://dx.doi.org/10.1016/j.brainres.2004.01.027
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Carland JE; Moorhouse AJ; Barry PH; Johnston G; Chebib M, 2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, vol. 279, pp. 54153 - 54160, http://dx.doi.org/10.1074/jbc.M410625200
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2004, 'Ligand-gated ion channels: mechanisms underlying ion selectivity', Progress in Biophysics and Molecular Biology, vol. 86, pp. 161 - 204, http://dx.doi.org/10.1016/j.pbiomolbio.2003.09.002
    Journal articles | 2004
    Associate Professor Andrew Moorhouse
    Katsurabayashi S; Kubota H; Moorhouse AJ; Akaike N, 2004, 'Differential modulation of evoked and spontaneous glycine release fromrat spinal cord glycinergic terminals by the cyclic AMP/protein kinaseA transduction cascade', Journal of Neurochemistry, vol. 91, pp. 657 - 666, http://dx.doi.org/10.1111/j.1471-4159.2004.02741.x
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', The Journal of Physiology, vol. 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Lee DJ; Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2003, 'The contribution of P250 (P-2`D) to ion selectivity and pore diameter in the human glycine receptor.', Neuroscience Letters, vol. 351, pp. 196 - 200, http://dx.doi.org/10.1016/j.neulet.2003.08.005
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Akaike N; Moorhouse AJ, 2003, 'Techniques: Applications of the Nerve - bouton preparation in Neuropharmacology', Trends in Pharmacological Sciences, vol. 24, pp. 44 - 47, http://dx.doi.org/10.1016/S0165-6147(02)00010-X
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Jeong H; Jan I; Moorhouse AJ; Akaike N, 2003, 'Activation of presynaptic glycine receptors facilitate glycine release from presynaptic terminals synapsing onto rat spinal sacral dorsal commissural nucleus nerons', The Journal of Physiology, vol. 550, pp. 373 - 383, http://dx.doi.org/10.1113/jphysiol.2003.041053
    Journal articles | 2003
    Associate Professor Andrew Moorhouse
    Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', Journal of Physiology, vol. 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524
    Journal articles | 2002
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; Pierce K; Schofield PR; Barry PH, 2002, 'Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion charge selectivity', Journal of General Physiology, vol. 119, pp. 393 - 410, http://dx.doi.org/10.1085/jgp.20028552
    Journal articles | 2002
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Keramidas A; Zaikine A; Zaykin A; Schofield PR; Barry PH, 2002, 'Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels', Journal of General Physiology, vol. 119, pp. 411 - 425, http://dx.doi.org/10.1085/jgp.20028553
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Kaur R; Zhu X; Moorhouse AJ; Barry PH, 2001, 'IP3-Gated Channels and their Occurrence Relative to CNG Channels in the Soma and Dendritic Knob of Rat Olfactory Receptor Neurons', Journal of Membrane Biology, vol. 181, pp. 91 - 105, https://www.ncbi.nlm.nih.gov/pubmed/11420596
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Anomalous Mole-Fraction Effects in Recombinat & Native Cyclic Nucleotide-Gated Channels in Rat Olfactory Receptor Neurons', Proceedings of the Royal Society of London Series B - Biological Sciences, vol. 268, pp. 1395 - 1403, http://dx.doi.org/10.1098/rspb.2001.1663
    Journal articles | 2001
    Associate Professor Andrew Moorhouse
    Kaur R; Zhu XO; Moorhouse AJ; Barry PH, 2001, 'Ip3-gated channels and their occurrence relative to CNG channels in the soma and dendritic knob of rat olfactory receptor neurons', Journal of Membrane Biology, vol. 181, pp. 91 - 105, http://dx.doi.org/10.1007/s00232-001-0013-5
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Qu W; Zhu X; Moorhouse AJ; Bieri S; Cunningham AM, 2000, 'Ion permeation and selectivity of wild-type recombinant rat (CNG (rOCNC1) chanels expressed in HEK293 cells', Journal of Membrane Biology, vol. 178, pp. 137 - 150, http://dx.doi.org/10.1007/s002320010021
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; French C; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion to cation selective', Biophysical Journal, vol. 78, pp. 247 - 259, http://dx.doi.org/10.1016/S0006-3495(00)76287-4
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Qu W; Moorhouse AJ; Rajendra S; Barry PH, 2000, 'Very negative potential for half-inactivation of and effects of anions on voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons', Journal of Membrane Biology, vol. 175, pp. 123 - 138, http://dx.doi.org/10.1007/s002320001061
    Journal articles | 2000
    Associate Professor Andrew Moorhouse
    Keramidas A; Moorhouse AJ; French CD; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective', Biophysical Journal, pp. 247 - 259
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Jacques P; Barry PH; Schofield PR, 1999, 'The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating', Molecular Pharmacology, vol. 55, pp. 386 - 395, http://dx.doi.org/10.1124/mol.55.2.386
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why', Clinical and Experimental Pharmacology and Physiology, vol. 26, pp. 935 - 936, http://dx.doi.org/10.1046/j.1440-1681.1999.03149.x
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Smith PR; Proks P; Moorhouse AJ, 1999, 'Direct effects of tolutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic beta-cells', Pflugers Archiv - European Journal of Physiology, vol. 437, pp. 577 - 588, http://dx.doi.org/10.1007/s004240050820
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Keramidas A; Kuhlmann L; Moorhouse AJ; Barry PH, 1999, 'Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA2-and EGTA3-) for use in electrophysiological experiments', Journal of Neuroscience Methods, vol. 89, pp. 41 - 47, http://dx.doi.org/10.1016/S0165-0270(99)00036-9
    Journal articles | 1999
    Associate Professor Andrew Moorhouse
    Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why?', Clinical and Experimental Pharmacology and Physiology, pp. 935 - 936
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Proks P; Moorhouse A; Smith PA; Ashcroft FM, 1996, 'Protein kinase C does not influence the tolbutamide sensitivity of K-ATP currents', DIABETOLOGIA, vol. 39, pp. 105 - 105, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VA49300106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Tucker SJ; Pessia M; Moorhouse AJ; Gribble F; Ashcroft FM; Maylie J; Adelman JP, 1996, 'Heteromeric channel formation and Ca2+-free media reduce the toxic effect of the weaver K 3.2 allele', FEBS Letters, vol. 390, pp. 253 - 257, http://dx.doi.org/10.1016/0014-5793(96)00635-7
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Ämmälä C; Moorhouse A; Gribble F; Ashfield R; Proks P; Smith PA; Sakura H; Coles B; Ashcroft SJH; Ashcroft FM, 1996, 'Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels', Nature, vol. 379, pp. 545 - 548, http://dx.doi.org/10.1038/379545a0
    Journal articles | 1996
    Associate Professor Andrew Moorhouse
    Ammala C; Moorhouse AJ; Ashcroft FM, 1996, 'The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying Kir6.1 expressed in human embroyonic kidney cells', The Journal of Physiology, vol. 494, pp. 709 - 714, http://dx.doi.org/10.1113/jphysiol.1996.sp021526
    Journal articles | 1995
    Associate Professor Andrew Moorhouse
    MOORHOUSE AJ; SPENCE I, 1995, 'SYNAPTIC TRANSMISSION, HYPOXIA AND ADENOSINE IN THE ISOLATED NEONATAL RAT SPINAL-CORD', JOURNAL OF PHYSIOLOGY-LONDON, vol. 489P, pp. P23 - P23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TH85400029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles |
    Associate Professor Andrew Moorhouse
    Takeda I; Yoshihara K; Cheung D; Agetsuma M; Tsuda M; Eto K; Moorhouse A; Nabekura J, 'Controlled activation of cortical astrocytes can reverse neuropathic chronic pain', , http://dx.doi.org/10.21203/rs.3.rs-150434/v1
  • Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Student Peer Assessment Using Moodle Workshop: Challenges in a COVID-19 world.', presented at UNSW Learning & Teaching Forum, 19 November 2020 - 20 November 2020
    Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Our challenges and triumphs with online peer assessment in a fully remote course.', presented at Australian Physiological Society Education Forum, 25 November 2020
    Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Online peer assessment: Challenges, triumphs and lessons learnt during COVID-19', presented at UNSW Medicine & Health Education Forum, UNSW Sydney, 04 December 2020
    Patents | 2018
    Associate Professor Andrew Moorhouse
    Kim Y; Bertrand P; Moorhouse A; Wong ACY; Craig A; Power J; Klugmann M; Krishnan A; Morris R, 2018, Methods for inhibiting neuron apoptosis and necrosis, Patent No. 2013286815, https://worldwide.espacenet.com/publicationDetails/biblio?CC=AU&NR=2013286815B2&KC=B2&FT=D
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Goulton C; Moorhouse A, 2015, 'Effects of the KCC2 membrane transporter on neuronal excitability and seizure models in the hippocampal slice preparation', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 140 - 140, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Khoshaba A; Power J; Inada H; Nabekura J; Moorhouse A, 2015, 'Measuring KCC2 function in brain slices using BCECF imaging', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 159 - 159, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Cheung D; Goulton C; Cooke M; Cowan A; Klugmann M; Moorhouse A, 2015, 'Effects of prolonged diazepam administration on hippocampal EEG and histology in a mouse model of temporal lobe epilepsy', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 138 - 138, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300315&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Associate Professor Andrew Moorhouse
    Kim YS; Moorhouse AJ; Bertrand PP; Klugmann M; Housley GD, 2013, 'Alternative splicing of Canonical Transient Receptor Potential type 3 (TRPC3) ion channel expression in the human brain', in Journal of Neurological Sciences vol 333, Elsevier, Vienna, Austria, pp. e654, presented at World Congress of Neurology, Vienna, Austria, 21 September 2013 - 26 September 2013, http://www.journals.elsevier.com/journal-of-the-neurological-sciences/
    Conference Presentations | 2013
    Associate Professor Andrew Moorhouse
    Moorhouse AJ, 2013, 'Upregulating KCC2 enhances neuronal inhibition. Oral presentation, Gage Conference on Ion Channels and Transporters', Canberra,, 17 April 2013 - 20 April 2013
    Conference Posters | 2013
    Associate Professor Andrew Moorhouse
    Khoshaba ; Power J; Moorhouse AJ, 2013, 'Quantifying KCC2 activity in isolated hippocampal neurons using fluorescent imaging. Poster presentation', Canberra, presented at Gage Conference on Ion Channels and Transporters, Canberra, 17 April 2013 - 20 April 2013
    Conference Posters | 2013
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2013, 'Experimental and theoretical validation of calculated liquid junction potentials in monovalent ion solutions and effects of divalent ions', RMIT, Melbourne, presented at 37th Annual Meeting of the Australian Society for Biophysics, RMIT, Melbourne, 24 November 2013 - 27 November 2013
    Conference Papers | 2012
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Sugiharto S; Carland JE; Lewis TM; Barry PH, 2012, 'Anion selectivity and counter-ion cation permeation in glycine receptor channels.', in FASEB JOURNAL Volume: 26 Published: APR 2012, American Physiology Society, Abs#, 901.2., San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310711303579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Patents | 2012
    Associate Professor Andrew Moorhouse
    Housley GD; Kim YS; Bertrand PP; Moorhouse AJ; Wong AC; Craig A; Power J; Klugmann M; Krishnan AV; Morris R, 2012, Methods for inhibiting neuron apoptosis and necrosis” (filed by New South Innovations – (UNSW) – Au Provisional Patent Application No. 2012902920, 6 July 2012)., AUSTRALIA, 2012, Patent No. 2012902920, status:%20Applied%20for%20(Provisional)%20Registered%20in%20names%20of%20(Inventors)
    Conference Presentations | 2011
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analysis, for the simple experimental measurement of liquid junction potentials', presented at Joint ASB-BioPhysChem 2011 Conference, University of Wollongong, NSW, Australia, 03 December 2011 - 06 December 2011
    Conference Papers | 2011
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analyses, for the simple experimental measurement of liquid junction potentials', Wollongong, presented at BioPhysChem 2011, a joint meeting of the RACI Physical Chemistry Division and the Australian Society for Biophysics,, Wollongong
    Conference Posters | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'Do divalent cations increase the anion-cation permeability in glycine receptor channels, even with initial offset and activity corrections?', Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Sciences, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102616&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels', presented at Curtin Conference, RMIT, Melbourne, VIC, 15 April 2009 - 17 April 2009
    Conference Posters | 2009
    Associate Professor Andrew Moorhouse
    Moorhouse A; Carland JE; Cooper MA; Sugiharto S; Jeong H-J; Lewis TM; Barry PH; Peters JA; Lambert JJ, 2009, 'Molecular determinants of ion permeation in glycine receptor-channels: characterising charged residues in the intracellular M3-M4 loop', Kyoto, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Societies, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102614&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Moorhouse AJ; Lewis TM, 2009, 'Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets', presented at 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, 29 November 2009
    Conference Papers | 2008
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2008, 'Resting microglia directly monitor synapses in vivo and determine the fate of ischemic terminals', in Neuroscience Research, Elsevier Sci Ireland Ltd, Clare, Ireland, pp. S152 - S152, presented at Neuroscience Research, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000261548101055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2008
    Associate Professor Andrew Moorhouse
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'The role of intracellular portals in glycine receptor ion permeation', presented at 32nd Annual Meeting of the Australian Society for Biophysics, Australian National University, Canberra, Australia, 28 September 2008 - 01 October 2008
    Conference Presentations | 2008
    Associate Professor Andrew Moorhouse
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'Charged residues in the intracellular loop affect the conductance of glycine α1 receptors', presented at Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, 12 November 2008 - 14 November 2008
    Conference Presentations | 2007
    Associate Professor Andrew Moorhouse
    Sugiharto S; Moorhouse AJ; Lewis TM; Schofield PR; Barry PH, 2007, 'The anion-cation permeability ratio in glycine receptor channels of different pore size is influenced by both counter-ions and divalent ions', presented at 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia
    Conference Presentations | 2001
    Associate Professor Andrew Moorhouse
    Zhu XO; Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Spermine block in alpha homomeric recombinant olfactory CNG channels', Vol. 80, pp. 633A - 633A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692202880&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Student Peer Assessment Using Moodle Workshop: Challenges in a COVID-19 world.', presented at UNSW Learning & Teaching Forum, 19 November 2020 - 20 November 2020
    Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Our challenges and triumphs with online peer assessment in a fully remote course.', presented at Australian Physiological Society Education Forum, 25 November 2020
    Conference Presentations | 2020
    Associate Professor Andrew Moorhouse
    Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Online peer assessment: Challenges, triumphs and lessons learnt during COVID-19', presented at UNSW Medicine & Health Education Forum, UNSW Sydney, 04 December 2020
    Patents | 2018
    Associate Professor Andrew Moorhouse
    Kim Y; Bertrand P; Moorhouse A; Wong ACY; Craig A; Power J; Klugmann M; Krishnan A; Morris R, 2018, Methods for inhibiting neuron apoptosis and necrosis, Patent No. 2013286815, https://worldwide.espacenet.com/publicationDetails/biblio?CC=AU&NR=2013286815B2&KC=B2&FT=D
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Goulton C; Moorhouse A, 2015, 'Effects of the KCC2 membrane transporter on neuronal excitability and seizure models in the hippocampal slice preparation', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 140 - 140, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Khoshaba A; Power J; Inada H; Nabekura J; Moorhouse A, 2015, 'Measuring KCC2 function in brain slices using BCECF imaging', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 159 - 159, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Andrew Moorhouse
    Cheung D; Goulton C; Cooke M; Cowan A; Klugmann M; Moorhouse A, 2015, 'Effects of prolonged diazepam administration on hippocampal EEG and histology in a mouse model of temporal lobe epilepsy', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 138 - 138, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300315&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Associate Professor Andrew Moorhouse
    Kim YS; Moorhouse AJ; Bertrand PP; Klugmann M; Housley GD, 2013, 'Alternative splicing of Canonical Transient Receptor Potential type 3 (TRPC3) ion channel expression in the human brain', in Journal of Neurological Sciences vol 333, Elsevier, Vienna, Austria, pp. e654, presented at World Congress of Neurology, Vienna, Austria, 21 September 2013 - 26 September 2013, http://www.journals.elsevier.com/journal-of-the-neurological-sciences/
    Conference Presentations | 2013
    Associate Professor Andrew Moorhouse
    Moorhouse AJ, 2013, 'Upregulating KCC2 enhances neuronal inhibition. Oral presentation, Gage Conference on Ion Channels and Transporters', Canberra,, 17 April 2013 - 20 April 2013
    Conference Posters | 2013
    Associate Professor Andrew Moorhouse
    Khoshaba ; Power J; Moorhouse AJ, 2013, 'Quantifying KCC2 activity in isolated hippocampal neurons using fluorescent imaging. Poster presentation', Canberra, presented at Gage Conference on Ion Channels and Transporters, Canberra, 17 April 2013 - 20 April 2013
    Conference Posters | 2013
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2013, 'Experimental and theoretical validation of calculated liquid junction potentials in monovalent ion solutions and effects of divalent ions', RMIT, Melbourne, presented at 37th Annual Meeting of the Australian Society for Biophysics, RMIT, Melbourne, 24 November 2013 - 27 November 2013
    Conference Papers | 2012
    Associate Professor Andrew Moorhouse
    Moorhouse AJ; Sugiharto S; Carland JE; Lewis TM; Barry PH, 2012, 'Anion selectivity and counter-ion cation permeation in glycine receptor channels.', in FASEB JOURNAL Volume: 26 Published: APR 2012, American Physiology Society, Abs#, 901.2., San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310711303579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Patents | 2012
    Associate Professor Andrew Moorhouse
    Housley GD; Kim YS; Bertrand PP; Moorhouse AJ; Wong AC; Craig A; Power J; Klugmann M; Krishnan AV; Morris R, 2012, Methods for inhibiting neuron apoptosis and necrosis” (filed by New South Innovations – (UNSW) – Au Provisional Patent Application No. 2012902920, 6 July 2012)., AUSTRALIA, 2012, Patent No. 2012902920, status:%20Applied%20for%20(Provisional)%20Registered%20in%20names%20of%20(Inventors)
    Conference Presentations | 2011
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analysis, for the simple experimental measurement of liquid junction potentials', presented at Joint ASB-BioPhysChem 2011 Conference, University of Wollongong, NSW, Australia, 03 December 2011 - 06 December 2011
    Conference Papers | 2011
    Associate Professor Andrew Moorhouse
    Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analyses, for the simple experimental measurement of liquid junction potentials', Wollongong, presented at BioPhysChem 2011, a joint meeting of the RACI Physical Chemistry Division and the Australian Society for Biophysics,, Wollongong
    Conference Posters | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'Do divalent cations increase the anion-cation permeability in glycine receptor channels, even with initial offset and activity corrections?', Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Sciences, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102616&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels', presented at Curtin Conference, RMIT, Melbourne, VIC, 15 April 2009 - 17 April 2009
    Conference Posters | 2009
    Associate Professor Andrew Moorhouse
    Moorhouse A; Carland JE; Cooper MA; Sugiharto S; Jeong H-J; Lewis TM; Barry PH; Peters JA; Lambert JJ, 2009, 'Molecular determinants of ion permeation in glycine receptor-channels: characterising charged residues in the intracellular M3-M4 loop', Kyoto, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Societies, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102614&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Associate Professor Andrew Moorhouse
    Barry PH; Sugiharto S; Carland JE; Moorhouse AJ; Lewis TM, 2009, 'Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets', presented at 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, 29 November 2009
    Conference Papers | 2008
    Associate Professor Andrew Moorhouse
    Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2008, 'Resting microglia directly monitor synapses in vivo and determine the fate of ischemic terminals', in Neuroscience Research, Elsevier Sci Ireland Ltd, Clare, Ireland, pp. S152 - S152, presented at Neuroscience Research, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000261548101055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2008
    Associate Professor Andrew Moorhouse
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'The role of intracellular portals in glycine receptor ion permeation', presented at 32nd Annual Meeting of the Australian Society for Biophysics, Australian National University, Canberra, Australia, 28 September 2008 - 01 October 2008
    Conference Presentations | 2008
    Associate Professor Andrew Moorhouse
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'Charged residues in the intracellular loop affect the conductance of glycine α1 receptors', presented at Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, 12 November 2008 - 14 November 2008
    Conference Presentations | 2007
    Associate Professor Andrew Moorhouse
    Sugiharto S; Moorhouse AJ; Lewis TM; Schofield PR; Barry PH, 2007, 'The anion-cation permeability ratio in glycine receptor channels of different pore size is influenced by both counter-ions and divalent ions', presented at 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia
    Conference Presentations | 2001
    Associate Professor Andrew Moorhouse
    Zhu XO; Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Spermine block in alpha homomeric recombinant olfactory CNG channels', Vol. 80, pp. 633A - 633A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692202880&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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