Dr Anupriya Aggarwal

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Anu is currently working as a post-doctoral scientist in the Immunovirology and Pathogenesis program at the Kirby Institute. Her main research interest is to study host-virus interactions in order to investigate and develop novel therapeutic strategies against HIV infected resting immune cells.

E-mail

aaggarwal@kirby.unsw.edu.au

Journal articles | 2024

Bedding MJ; Franck C; Johansen-Leete J; Aggarwal A; Maxwell JWC; Patel K; Hawkins PME; Low JKK; Siddiquee R; Sani HM; Ford DJ; Turville S; Mackay JP; Passioura T; Christie M; Payne RJ, 2024, 'Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity', ACS Chemical Biology, 19, pp. 141 - 152, http://dx.doi.org/10.1021/acschembio.3c00568

Journal articles | 2024

Harrison K; Carlos PW; Ullrich S; Aggarwal A; Johansen-Leete J; Sasi VM; Barter I; Maxwell JWC; Bedding MJ; Larance M; Turville S; Norman A; Jackson CJ; Nitsche C; Payne RJ, 2024, 'Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity', Chemistry - A European Journal, http://dx.doi.org/10.1002/chem.202401606

Journal articles | 2024

Phetsouphanh C; Jacka B; Ballouz S; Jackson KJL; Wilson DB; Manandhar B; Klemm V; Tan HX; Wheatley A; Aggarwal A; Akerman A; Milogiannakis V; Starr M; Cunningham P; Turville SG; Kent SJ; Byrne A; Brew BJ; Darley DR; Dore GJ; Kelleher AD; Matthews GV, 2024, 'Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-47720-8

Journal articles | 2024

Singer J; Tunbridge MJ; Shi B; Perkins GB; Chai CS; Salehi T; Sim BZ; Kireta S; Johnston JK; Akerman A; Milogiannakis V; Aggarwal A; Turville S; Hissaria P; Ying T; Wu H; Grubor-Bauk B; Coates PT; Chadban SJ, 2024, 'Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial', Vaccines, 12, http://dx.doi.org/10.3390/vaccines12060608

Journal articles | 2024

Zhang L; Dopfer-Jablonka A; Cossmann A; Stankov MV; Graichen L; Moldenhauer AS; Fichter C; Aggarwal A; Turville SG; Behrens GMN; Pöhlmann S; Hoffmann M, 2024, 'Rapid spread of the SARS-CoV-2 JN.1 lineage is associated with increased neutralization evasion', iScience, 27, http://dx.doi.org/10.1016/j.isci.2024.109904

Journal articles | 2023

Akerman A; Milogiannakis V; Jean T; Esneau C; Silva MR; Ison T; Fichter C; Lopez JA; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster CSP; Sato K; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Britton W; Sandgren K; Bull R; Lloyd A; Triccas J; Tangye S; Bartlett NW; Darley D; Matthews G; Stark DJ; Petoumenos K; Rawlinson WD; Murrell B; Brilot F; Cunningham AL; Kelleher AD; Aggarwal A; Turville SG, 2023, 'Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level', eBioMedicine, 90, http://dx.doi.org/10.1016/j.ebiom.2023.104545

Journal articles | 2023

Alcheikh A; Perkins GB; Pucar PA; Cecchin A; Chai CS; Tunbridge M; Akerman A; Aggarwal A; Milogiannakis V; Turville S; Allen S; Hissaria P; Banovic T; Coates PT; Ross DM, 2023, 'Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients', Blood Cancer Journal, 13, http://dx.doi.org/10.1038/s41408-023-00824-8

Journal articles | 2023

Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Klemm V; Munier CML; Hoppe AC; Tea F; Pillay A; Stella AO; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J; Carey Hoppe A, 2023, 'Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses', American Journal of Hematology, 98, pp. 131 - 139, http://dx.doi.org/10.1002/ajh.26619

Journal articles | 2023

Bowden-Reid E; Ledger S; Zhang Y; Di Giallonardo F; Aggarwal A; Stella AO; Akerman A; Milogiannakis V; Walker G; Rawlinson W; Turville S; Kelleher AD; Ahlenstiel C, 2023, 'Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2', Antiviral Research, 217, http://dx.doi.org/10.1016/j.antiviral.2023.105677

Journal articles | 2023

Lee WS; Tan HX; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent HE; Aggarwal A; Turville SG; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson DA; Cromer D; Davenport MP; Kent SJ; Juno JA; Khoury DS; Wheatley AK, 2023, 'Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.adg5301

Journal articles | 2023

Loo L; Waller MA; Moreno CL; Cole AJ; Stella AO; Pop OT; Jochum AK; Ali OH; Denes CE; Hamoudi Z; Chung F; Aggarwal A; Low JKK; Patel K; Siddiquee R; Kang T; Mathivanan S; Mackay JP; Jochum W; Flatz L; Hesselson D; Turville S; Gregory Neely G, 2023, 'Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs', PLoS Biology, 21, http://dx.doi.org/10.1371/journal.pbio.3001967

Journal articles | 2023

Pillay A; Yeola A; Tea F; Denkova M; Houston S; Burrell R; Merheb V; Lee FXZ; Lopez JA; Moran L; Jadhav A; Sterling K; Lai CL; Vitagliano TL; Aggarwal A; Catchpoole D; Wood N; Phan TG; Nanan R; Hsu P; Turville SG; Britton PN; Brilot F, 2023, 'Infection and Vaccine Induced Spike Antibody Responses Against SARS-CoV-2 Variants of Concern in COVID-19-Naïve Children and Adults', Journal of Clinical Immunology, 43, pp. 1706 - 1723, http://dx.doi.org/10.1007/s10875-023-01540-5

Journal articles | 2023

Poumbourios P; Langer C; Boo I; Zakir T; Center RJ; Akerman A; Milogiannakis V; Aggarwal A; Johnstone BA; Ha J; Coulibaly F; Turville SG; Drummer HE, 2023, 'Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core', PLoS Pathogens, 19, http://dx.doi.org/10.1371/journal.ppat.1010981

Journal articles | 2023

Thijssen V; Hurdiss DL; Debski-Antoniak OJ; Spence MA; Franck C; Norman A; Aggarwal A; Mokiem NJ; van Dongen DAA; Vermeir SW; Liu M; Li W; Chatziandreou M; Donselaar T; Du W; Drulyte I; Bosch BJ; Snijder J; Turville SG; Payne RJ; Jackson CJ; van Kuppeveld FJM; Jongkees SAK, 2023, 'A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein', Proceedings of the National Academy of Sciences of the United States of America, 120, http://dx.doi.org/10.1073/pnas.2303292120

Journal articles | 2023

Troelnikov A; Armour B; Putty T; Aggarwal A; Akerman A; Milogiannakis V; Chataway T; King J; Turville S; Gordon TP; Wang JJ, 2023, 'Imprinted repertoire restriction in immunodeficiency', Pathology, 55, pp. S28 - S28, http://dx.doi.org/10.1016/j.pathol.2022.12.093

Journal articles | 2023

Troelnikov A; Armour B; Putty T; Aggarwal A; Akerman A; Milogiannakis V; Chataway T; King J; Turville SG; Gordon TP; Wang JJ, 2023, 'Immunoglobulin repertoire restriction characterizes the serological responses of patients with predominantly antibody deficiency', Journal of Allergy and Clinical Immunology, 152, pp. 290 - 301.e7, http://dx.doi.org/10.1016/j.jaci.2023.02.033

Journal articles | 2022

Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Stella AO; Kindinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Jean T; Foster CSP; Christ D; Hoppe AC; Munier ML; Darley D; Churchill M; Stark DJ; Matthews G; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern', eBioMedicine, 84, http://dx.doi.org/10.1016/j.ebiom.2022.104270

Journal articles | 2022

Aggarwal A; Stella AO; Henry CC; Narayan K; Turville SG, 2022, 'Embedding of HIV Egress within Cortical F-Actin', Pathogens, 11, http://dx.doi.org/10.3390/pathogens11010056

Journal articles | 2022

Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, 7, pp. 896 - 908, http://dx.doi.org/10.1038/s41564-022-01135-7

Journal articles | 2022

Ashhurst AS; Johansen MD; Maxwell JWC; Stockdale S; Ashley CL; Aggarwal A; Siddiquee R; Miemczyk S; Nguyen DH; Mackay JP; Counoupas C; Byrne SN; Turville S; Steain M; Triccas JA; Hansbro PM; Payne RJ; Britton WJ, 2022, 'Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-34297-3

Journal articles | 2022

Ashhurst AS; Tang AH; Fajtová P; Yoon MC; Aggarwal A; Bedding MJ; Stoye A; Beretta L; Pwee D; Drelich A; Skinner D; Li L; Meek TD; McKerrow JH; Hook V; Tseng CT; Larance M; Turville S; Gerwick WH; O'Donoghue AJ; Payne RJ, 2022, 'Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L', Journal of Medicinal Chemistry, 65, pp. 2956 - 2970, http://dx.doi.org/10.1021/acs.jmedchem.1c01494

Journal articles | 2022

Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson SC; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer DE; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2022, 'Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses', Cell Reports, 38, pp. 110345, http://dx.doi.org/10.1016/j.celrep.2022.110345

Journal articles | 2022

Counoupas C; Pino P; Stella AO; Ashley C; Lukeman H; Bhattacharyya ND; Tada T; Anchisi S; Metayer C; Martinis J; Aggarwal A; Dcosta BM; Britton WJ; Kint J; Wurm MJ; Landau NR; Steain M; Turville SG; Wurm FM; David SA; Triccas JA, 2022, 'High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens', Microbiology Spectrum, 10, http://dx.doi.org/10.1128/spectrum.01695-21

Journal articles | 2022

Garcia-Valtanen P; Hope CM; Masavuli MG; Yeow AEL; Balachandran H; Mekonnen ZA; Al-Delfi Z; Abayasingam A; Agapiou D; Stella AO; Aggarwal A; Bouras G; Gummow J; Ferguson C; O'Connor S; McCartney EM; Lynn DJ; Maddern G; Gowans EJ; Reddi BAJ; Shaw D; Kok-Lim C; Beard MR; Weiskopf D; Sette A; Turville SG; Bull RA; Barry SC; Grubor-Bauk B, 2022, 'SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents', Cell Reports Medicine, 3, http://dx.doi.org/10.1016/j.xcrm.2022.100651

Journal articles | 2022

George PM; Reed A; Desai SR; Devaraj A; Faiez TS; Laverty S; Kanwal A; Esneau C; Liu MKC; Kamal F; Man WDC; Kaul S; Singh S; Lamb G; Faizi FK; Schuliga M; Read J; Burgoyne T; Pinto AL; Micallef J; Bauwens E; Candiracci J; Bougoussa M; Herzog M; Raman L; Ahmetaj-Shala B; Turville S; Aggarwal A; Farne HA; Pria AD; Aswani AD; Patella F; Borek WE; Mitchell JA; Bartlett NW; Dokal A; Xu XN; Kelleher P; Shah A; Singanayagam A, 2022, 'A persistent neutrophil-associated immune signature characterizes post-COVID-19 pulmonary sequelae', Science Translational Medicine, 14, http://dx.doi.org/10.1126/scitranslmed.abo5795

Journal articles | 2022

Johansen-Leete J; Ullrich S; Fry SE; Frkic R; Bedding MJ; Aggarwal A; Ashhurst AS; Ekanayake KB; Mahawaththa MC; Sasi VM; Luedtke S; Ford DJ; O'Donoghue AJ; Passioura T; Larance M; Otting G; Turville S; Jackson CJ; Nitsche C; Payne RJ, 2022, 'Antiviral cyclic peptides targeting the main protease of SARS-CoV-2', Chemical Science, 13, pp. 3826 - 3836, http://dx.doi.org/10.1039/d1sc06750h

Journal articles | 2022

Perkins GB; Tunbridge M; Salehi T; Chai CS; Kireta S; Johnston J; Penko D; Nitschke J; Yeow AEL; Al-Delfi Z; Drogemuller CJ; Garcia-Valtanen P; Masavuli MG; Hope CM; Singer J; Aggarwal A; Ospina Stella A; Turville SG; Hurtado PR; Barry SC; Hissaria P; Grubor-Bauk B; Chadban SJ; Coates PT, 2022, 'Concurrent vaccination of kidney transplant recipients and close household cohabitants against COVID-19', Kidney International, 101, pp. 1077 - 1080, http://dx.doi.org/10.1016/j.kint.2022.02.015

Journal articles | 2022

Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks ML; Law H; Danwilai T; Starr M; Munier CML; Christ D; Singh M; Croucher PI; Brilot-Turville F; Turville S; Phan TG; Dore GJ; Darley D; Cunningham P; Matthews GV; Kelleher AD; Zaunders JJ, 2022, 'High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1032911

Journal articles | 2022

Power H; Wu J; Turville S; Aggarwal A; Valtchev P; Schindeler A; Dehghani F, 2022, 'Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein', Bioorganic Chemistry, 119, http://dx.doi.org/10.1016/j.bioorg.2021.105574

Journal articles | 2022

Rankin K; Beaton B; Sasson S; Raedemaecker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Patel M; Klemm V; Munier CML; Carey Hoppe A; Tea F; Pillay A; Ospina A; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA', HemaSphere, 6, pp. 1958 - 1959, http://dx.doi.org/10.1097/01.hs9.0000851180.32970.18

Journal articles | 2022

Shen Y; Freeman JA; Holland J; Naidu K; Solterbeck A; Van Bilsen N; Downe P; Kerridge I; Wallman L; Akerman A; Aggarwal A; Milogiannakis V; Martins Costa Gomes G; Doyle CM; Sandgren KJ; Turville S; Cunningham AL; Mulligan SP, 2022, 'Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion', Blood, 140, pp. 2709 - 2721, http://dx.doi.org/10.1182/blood.2022017814

Journal articles | 2022

Singh S; Sharma A; Gupta A; Joshi M; Aggarwal A; Soni N; Sana ; Jain D; Verma P; Khandelwal D; Singh V, 2022, 'Demographic comparison of the first, second and third waves of COVID-19 in a tertiary care hospital at Jaipur, India', Lung India, 39, pp. 525 - 531, http://dx.doi.org/10.4103/lungindia.lungindia_265_22

Journal articles | 2022

Spillings BL; Day CJ; Garcia-Minambres A; Aggarwal A; Condon ND; Haselhorst T; Purcell DFJ; Turville SG; Stow JL; Jennings MP; Mak J, 2022, 'Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry', Cell Reports, 38, http://dx.doi.org/10.1016/j.celrep.2022.110296

Journal articles | 2021

Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA; Burnett D, 2021, 'Long-term persistence of RBD⁺ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228

Journal articles | 2021

Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Warden A; Stella AO; Aggarwal A; Caterson ID; Phetsouphanh C; Turville S; Kelleher AD; Brilot F; Trotman J, 2021, 'Efficacy of Vaccine BNT162b2 (Pfizer-BioNTech) in Individuals with Waldenstrom's Macroglobulinemia and Follicular Lymphoma in Australia', BLOOD, 138, http://dx.doi.org/10.1182/blood-2021-149348

Journal articles | 2021

Burnett DL; Jackson KJL; Langley DB; Aggrawal A; Stella AO; Johansen MD; Balachandran H; Lenthall H; Rouet R; Walker G; Saunders BM; Singh M; Li H; Henry JY; Jackson J; Stewart AG; Witthauer F; Spence MA; Hansbro NG; Jackson C; Schofield P; Milthorpe C; Martinello M; Schulz SR; Roth E; Kelleher A; Emery S; Britton WJ; Rawlinson WD; Karl R; Schäfer S; Winkler TH; Brink R; Bull RA; Hansbro PM; Jäck HM; Turville S; Christ D; Goodnow CC, 2021, 'Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability', Immunity, 54, pp. 2908 - 2921.e6, http://dx.doi.org/10.1016/j.immuni.2021.10.019

Journal articles | 2021

Capraro A; Wong S; Adhikari A; Allan K; Patel H; Zhong L; Raftery M; Jaffe A; Yeang M; Aggarwal A; Wu L; Pandzic E; Whan R; Turville S; Vittorio O; Bull R; Kaakoush N; Rawlinson W; Tedla N; Vafaee F; Waters S, 2021, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453

Journal articles | 2021

Counoupas C; Johansen MD; Stella AO; Nguyen DH; Ferguson AL; Aggarwal A; Bhattacharyya ND; Grey A; Hutchings O; Patel K; Siddiquee R; Stewart EL; Feng CG; Hansbro NG; Palendira U; Steain MC; Saunders BM; Low JKK; Mackay JP; Kelleher AD; Britton WJ; Turville SG; Hansbro PM; Triccas JA, 2021, 'A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection', npj Vaccines, 6, http://dx.doi.org/10.1038/s41541-021-00406-4

Journal articles | 2021

Fichter C; Aggarwal A; Wong AKH; McAllery S; Mathivanan V; Hao B; Macrae H; Churchill MJ; Gorry PR; Roche M; Gray LR; Turville S, 2021, 'Modular lentiviral vectors for highly efficient transgene expression in resting immune cells', Viruses, 13, http://dx.doi.org/10.3390/v13061170

Journal articles | 2021

Norman A; Franck C; Christie M; Hawkins PME; Patel K; Ashhurst AS; Aggarwal A; Low JKK; Siddiquee R; Ashley CL; Steain M; Triccas JA; Turville S; MacKay JP; Passioura T; Payne RJ, 2021, 'Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display', ACS Central Science, 7, pp. 1001 - 1008, http://dx.doi.org/10.1021/acscentsci.0c01708

Journal articles | 2021

Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Fichter C; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffmann M; Pöhlman S; Mazigi O; Christ D; Rockett RJ; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2021, 'SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants', PLoS Medicine, 18, http://dx.doi.org/10.1371/journal.pmed.1003656

Journal articles | 2020

Stelzer-Braid S; Walker GJ; Aggarwal A; Isaacs SR; Yeang M; Naing Z; Ospina Stella A; Turville SG; Rawlinson WD, 2020, 'Virus isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for diagnostic and research purposes', Pathology, 52, pp. 760 - 763, http://dx.doi.org/10.1016/j.pathol.2020.09.012

Journal articles | 2020

Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffman M; Pöhlmann S; Dwyer DE; Rockett R; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2020, 'SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants', , http://dx.doi.org/10.1101/2020.12.19.20248567

Journal articles | 2020

Van Bockel D; Munier CML; Turville S; Badman SG; Walker G; Stella AO; Aggarwal A; Yeang M; Condylios A; Kelleher AD; Applegate TL; Vallely A; Whiley D; Rawlinson W; Cunningham P; Kaldor J; Guy R, 2020, 'Evaluation of commercially available viral transport medium (VTM) for SARS-CoV-2 inactivation and use in point-of-care (POC) testing', Viruses, 12, pp. 1208, http://dx.doi.org/10.3390/v12111208

Journal articles | 2019

Aggarwal A; Ospina Stella A; Henry C; Narayan K; Turville S, 2019, 'HIV corruption of the Arp2/3-Cdc42-IQGAP1 axis to hijack cortical F-Actin to promote cell-cell viral spread', , http://dx.doi.org/10.1101/2019.12.13.873612

Journal articles | 2018

Ledger S; Howe A; Turville S; Aggarwal A; Savkovic B; Ong A; Wolstein O; Boyd M; Millington M; Gorry PR; Murray JM; Symonds G, 2018, 'Analysis and dissociation of anti-HIV effects of shRNA to CCR5 and the fusion inhibitor C46', Journal of Gene Medicine, 20, http://dx.doi.org/10.1002/jgm.3006

Journal articles | 2018

Márquez CL; Lau D; Walsh J; Shah V; McGuinness C; Wong A; Aggarwal A; Parker MW; Jacques DA; Turville S; Böcking T, 2018, 'Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis', eLife, 7, http://dx.doi.org/10.7554/eLife.34772

Journal articles | 2017

Aggarwal A; Hitchen TL; Ootes L; McAllery S; Wong A; Nguyen K; McCluskey A; Robinson PJ; Turville SG, 2017, 'HIV infection is influenced by dynamin at 3 independent points in the viral life cycle', Traffic, 18, pp. 392 - 410, http://dx.doi.org/10.1111/tra.12481

Journal articles | 2017

Aggarwal A; Turville SG, 2017, 'Resolving the Sites of HIV Entry: Dynamin Networks Hold the Key', Journal of Cell Signaling, 02, http://dx.doi.org/10.4172/2576-1471.1000173

Journal articles | 2017

Xu Y; Phetsouphanh C; Suzuki K; Aggrawal A; Graff-Dubois S; Roche M; Bailey M; Alcantara S; Cashin K; Sivasubramaniam R; Koelsch KK; Autran B; Harvey R; Gorry PR; Moris A; Cooper DA; Turville S; Kent SJ; Kelleher AD; Zaunders J, 2017, 'HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells', Frontiers in Immunology, 8, http://dx.doi.org/10.3389/fimmu.2017.00376

Journal articles | 2014

Aggarwal A; Turville SG, 2014, 'Imaging HIV entry and egress', Microbiology Australia

Journal articles | 2014

Eyre NS; Fiches GN; Aloia AL; Helbig KJ; McCartney EM; McErlean CSP; Li K; Aggarwal A; Turville SG; Beard MR, 2014, 'Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection', Journal of Virology, 88, pp. 3636 - 3652, http://dx.doi.org/10.1128/JVI.02490-13

Journal articles | 2013

Aggarwal A; Mcallery S; Turville S, 2013, 'Revising the role of myeloid cells in HIV pathogenesis', Current HIV/AIDS Reports, 10, pp. 3 - 11, http://dx.doi.org/10.1007/s11904-012-0149-1

Journal articles | 2012

Aggarwal A; Iemma T; Shih I; Newsome TP; Mcallery S; Cunningham A; Turville S, 2012, 'Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells', PLoS Pathogens, 8, pp. e1002762, http://dx.doi.org/10.1371/journal.ppat.1002762

Journal articles | 2012

Aggarwal A; Saksena MM; Boadle RA; Alam W; Kelly BJ; Diefenbach RJ; Cunningham AL, 2012, 'Ultrastructural visualization of individual tegument protein dissociation during entry of herpes simplex virus type 1 into human and rat dorsal root ganglion neurons.', Journal of Virology

Journal articles | 2009

Miranda-Saksena M; Boadle RA; Aggarwal A; Tijono B; Rixon FJ; Diefenbach RJ; Cunningham AL, 2009, 'Herpes simplex virus utilizes the large secretory vesicle pathway for anterograde transport of tegument and envelope proteins and for viral exocytosis from growth cones of human fetal axons', Journal of Virology, 83, pp. 3197 - 3199, http://dx.doi.org/10.1128/JVI.01579-08
Preprints | 2023

Aggarwal A; Fichter C; Milogiannakis V; Ison T; Silva MR; Esneau C; Bartlett N; Burrell L; Patel S; Churchill M; Angelovich T; Parry R; Sng J; Neely G; Moreno C; Loo L; Kelleher A; Brilot F; Khromykh A; Turville S, 2023, TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2, http://dx.doi.org/10.1101/2023.09.22.558930

Conference Abstracts | 2023

Czuba-Wojnilowicz E; Klemm V; Cortez-Jugo C; Turville S; Aggarwal A; Caruso F; Kelleher AD; Ahlenstiel CL, 2023, 'Layer-by-Layer Particles Deliver Epigenetic Silencing siRNA to HIV-1 Latent Reservoir Cell Types', in Molecular Pharmaceutics, Vol. 20, pp. 2039 - 2052, http://dx.doi.org/10.1021/acs.molpharmaceut.2c01030

Preprints | 2023

Lee WS; Tan H-X; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent H; Aggarwal A; Turville S; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson D; Cromer D; Davenport M; Kent S; Juno J; Khoury D; Wheatley A, 2023, Durable reprogramming of neutralising antibody responses following breakthrough Omicron infection, , http://dx.doi.org/10.1101/2023.02.19.23286159

Preprints | 2023

Moreno C; Castanheira F; Stella AO; Chung F; Aggarwal A; Cole A; Loo L; Dupuy A; Kong Y; Hagimola L; Fenwick J; Coleman P; Willson M; Bui-Marinos M; Hesselson D; Gamble J; Passam F; Turville S; Kubes P; Neely G, 2023, P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium, , http://dx.doi.org/10.1101/2023.02.13.528235

Preprints | 2023

Perkins G; Hope C; Chai CS; Tunbridge M; Sterling S; Webb K; Yap J; Yeow AEL; Masavuli M; Kireta S; Zuiani J; Akerman A; Aggarwal A; Milogiannakis V; Roberts M; Wilson W; Hurtado P; Turville S; Grubor-Bauk B; Barry S; Coates T; Ravindran J; Hissaria P, 2023, Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy, http://dx.doi.org/10.1101/2023.12.04.23299409

Preprints | 2023

Phetsouphanh C; Jacka B; Ballouz S; Jackson KJL; Wilson D; Manandhar B; Klemm V; Tan H-X; Wheatley A; Aggarwal A; Akerman A; Milogiannakis V; Starr M; Cunningham P; Turville S; Kent S; Byrne A; Brew B; Darley D; Dore G; Kelleher A; Matthews G, 2023, Improvement of immune dysregulation and health-related quality of life in individuals with long COVID at 24-months following SARS-CoV-2 infection, http://dx.doi.org/10.1101/2023.08.27.23294704

Preprints | 2022

Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Coppola G; Yeang M; Jean T; Foster C; Hoppe AC; Ling Munier M; Darley D; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, 2022, SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, http://dx.doi.org/10.1101/2022.07.07.22277128

Preprints | 2022

Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Yeang M; Jean T; Foster C; Hoppe AC; Munier ML; Darley D; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, 2022, SARS-CoV-2 Omicron BA.5: Evolving Tropism and Evasion of Potent Humoral Responses and Resistance to Clinical Immunotherapeutics Relative to Viral Variants of Concern, http://dx.doi.org/10.2139/ssrn.4157473

Preprints | 2022

Aggarwal A; Stella A; Akerman A; Walker G; Milogiannakis V; McAllery S; Esneau C; Silva MR; Lu Y; Forster C; Hal SV; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Darley D; Matthews G; Starck D; Robosa R; Bartlett N; Rawlinson W; Kelleher A; Turville S, 2022, Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants, http://dx.doi.org/10.21203/rs.3.rs-1210846/v1

Preprints | 2022

Ashhurst A; Johansen M; Maxwell J; Ashley C; Aggarwal A; Siddiquee R; Miemczyk S; Nguyen D; Mackay J; Counoupas C; Byrne S; Turville S; Steain M; Triccas J; Hansbro P; Payne R; Britton W, 2022, Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice, , http://dx.doi.org/10.21203/rs.3.rs-1179181/v1

Preprints | 2022

Loo L; Waller M; Cole A; Stella A; Moreno C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddiquee R; Mackay J; Turville S; Hesselson D; Neely G, 2022, LRRC15 suppresses SARS-CoV-2 infection and controls collagen production, , http://dx.doi.org/10.21203/rs.3.rs-1172665/v1

Preprints | 2022

Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks M; Law H; Danwilai T; Starr M; Munier ML; Christ D; Singh M; Croucher P; Brilot-Turville F; Turville S; Phan TG; Dore G; Darley D; Cunningham P; Matthews G; Kelleher A; Zaunders J, 2022, High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells, http://dx.doi.org/10.1101/2022.07.22.22277947

Preprints | 2022

Pillay A; Yeola A; Tea F; Denkova M; Houston S; Burrell R; Merheb V; Lee FXZ; Moran L; Jadhav A; Sterling K; Lai CL; Vitagliano TL; Aggarwal A; Catchpoole D; Wood N; Phan TG; Nanan R; Hsu P; Turville SG; Britton PN; Brilot F, 2022, Infection and vaccine induced Spike antibody responses against SARS-CoV-2 Variants of concern in immune naïve children and adults, , http://dx.doi.org/10.21203/rs.3.rs-2262275/v1

Preprints | 2022

Poumbourios P; Langer C; Boo I; Zakir T; Center R; Akerman A; Milogiannakis V; Aggarwal A; Turville S; Drummer H, 2022, Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core, http://dx.doi.org/10.1101/2022.11.08.515567

Preprints | 2022

Thijssen V; Hurdiss DL; Debski-Antoniak OJ; Spence MA; Franck C; Norman A; Aggarwal A; Mokiem NJ; van Dongen DAA; Vermeir SW; Liu M; Li W; Chatziandreou M; Donselaar T; Du W; Drulyte I; Bosch B-J; Snijder J; Turville S; Payne RJ; Jackson CJ; van Kuppeveld FJM; Jongkees SAK, 2022, A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein, , http://dx.doi.org/10.1101/2022.11.11.516114

Conference Abstracts | 2022

Troelnikov A; Wang JJ; Armour B; Putty T; Aggarwal A; Akerman A; Milogiannakis V; Smith A; Hughes T; Turville S; Chataway T; King J; Gordon TP, 2022, 'MOLECULAR PROFILING UNCOVERS RESTRICTED ANTIBODY REPERTOIRES FOLLOWING COVID-19 VACCINATION IN PREDOMINANT ANTIBODY DEFICIENCIES', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 52, pp. 31 - 31, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862654200083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints | 2021

Aggarwal A; Stella AO; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Henry J; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fichter C; Hoppe AC; Munier ML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2021, SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, http://dx.doi.org/10.1101/2021.12.14.21267772

Preprints | 2021

Counoupas C; Pino P; Stella A; Ashley C; Lukeman H; Bhattacharyya N; Tada T; Anchisi S; Metayer C; Martinis J; Aggarwal A; Dcosta B; Kint J; Wurm M; Landau N; Steain M; Turville S; Wurm F; David S; Triccas J, 2021, Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens, , http://dx.doi.org/10.1101/2021.08.18.456891

Preprints | 2021

Garcia-Valtanen P; Hope C; Masavuli M; Lip Yeow AE; Balachandran H; Mekonnen Z; Al-Delfi Z; Abayasingam A; Agapiou D; Stella AO; Aggarwal A; Gummow J; Ferguson C; O’Connor S; McCartney E; Lynn D; Maddern G; Gowans E; Reddi BAJ; Shaw D; Kok-Lim C; Turville S; Beard M; Weiskopf D; Sette A; Bull R; Barry S; Grubor-Bauk B, 2021, COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection, , http://dx.doi.org/10.1101/2021.11.08.21266035

Preprints | 2021

Johansen-Leete J; Ullrich S; Fry S; Frkic R; Bedding M; Aggarwal A; Ashhurst A; Ekanayake K; Mahawaththa M; Sasi V; Passioura T; Larance M; Otting G; Turville S; Jackson C; Nitsche C; Payne R, 2021, Discovery of Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 via mRNA Display, , http://dx.doi.org/10.1101/2021.08.23.457419

Preprints | 2021

Loo L; Waller M; Moreno C; Cole A; Stella AO; Pop O-T; Jochum A-K; Ali OH; Denes C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddiquee R; Kang T; Mathivanan S; Mackay J; Flatz L; Hesselson D; Turville S; Neely G, 2021, Fibroblast-expressed LRRC15 suppresses SARS-CoV-2 infection and controls antiviral and antifibrotic transcriptional programs, , http://dx.doi.org/10.1101/2021.11.09.467981

Preprints | 2020

Ashhurst AS; Tang AH; Fajtová P; Yoon M; Aggarwal A; Stoye A; Larance M; Beretta L; Drelich A; Skinner D; Li L; Meek TD; McKerrow JH; Hook V; Tseng C-TK; Turville S; Gerwick WH; O'Donoghue AJ; Payne RJ, 2020, Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L., , http://dx.doi.org/10.1101/2020.12.23.424111

Preprints | 2020

Counoupas C; Johansen M; Stella A; Nguyen D; Ferguson A; Aggarwal A; Bhattacharyya N; Grey A; Patel K; Siddiquee R; Stewart E; Feng C; Hansbro N; Palendira U; Steain M; Saunders B; Low J; Mackay J; Kelleher A; Britton W; Turville S; Hansbro P; Triccas J, 2020, A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice, , http://dx.doi.org/10.1101/2020.12.10.419044

Preprints | 2020

Norman A; Franck C; Christie M; Hawkins P; Patel K; Ashhurst A; Aggarwal A; Low J; Siddiquee R; Ashley C; Steain M; Triccas J; Turville S; Mackay J; Passioura T; Payne R, 2020, Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display, , http://dx.doi.org/10.1101/2020.12.22.424069

Conference Abstracts | 2018

Wong A; Aggarwal A; Atthi O; Hao B; Macrae H; Churchill M; Kelleher A; Turville S, 2018, 'Modular gene therapy vectors for gene therapy cure in resting immune cells', in JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, JOHN WILEY & SONS LTD, Vol. 21, pp. 4 - 4, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000440002700009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2016

Xu Y; Bailey M; Phetsouphanh C; Harvey R; Turville S; Aggarwal A; Wong A; Suzuki K; Graff-Dubois S; Autran B; Moris A; Munier ML; Koelsch K; Kent S; Zaunders J; Kelleher A, 2016, 'Accumulation of follicular T Helper (Tfh) cells, despite preferential infection, allows establishment of a large and unexpected viral reservoir during HIV infection', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 264 - 264, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400533&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints |

Abayasingam A; Balachandran H; Agapiou D; Rodrigo C; Keoshkerian E; Li H; Brasher N; Christ D; Rouet R; Burnett D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson S; Tea F; Pilli D; Tedla N; Lloyd AR; Martinello M; Bull RA; Group COSINS, Long-Term Persistence of Neutralizing Memory B Cells in SARS-CoV-2, , http://dx.doi.org/10.2139/ssrn.3732365

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