Professor Christopher Ormandy

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Phone

9295 8100

E-mail

c.ormandy@unsw.edu.au

Book Chapters | 2001

Ormandy CJ; Horseman NJ; Naylor MJ; Harris J; Robertson F; Binart N; Kelly PA, 2001, 'Mammery Gland Development', in Horseman ND (ed.), Prolactin, Kluwer Academic Publishers, Boston, pp. 219 - 232
Journal articles | 2022

Ho WHJ; Law AMK; Masle-Farquhar E; Castillo LE; Mawson A; O’Bryan MK; Goodnow CC; Gallego-Ortega D; Oakes SR; Ormandy CJ, 2022, 'Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases', Breast Cancer Research, 24, http://dx.doi.org/10.1186/s13058-022-01525-z

Journal articles | 2022

Law AMK; Chen J; Colino-Sanguino Y; Fuente LRDL; Fang G; Grimes SM; Lu H; Huang RJ; Boyle ST; Venhuizen J; Castillo L; Tavakoli J; Skhinas JN; Millar EKA; Beretov J; Rossello FJ; Tipper JL; Ormandy CJ; Samuel MS; Cox TR; Martelotto L; Jin D; Valdes-Mora F; Ji HP; Gallego-Ortega D, 2022, 'ALTEN: A High-Fidelity Primary Tissue-Engineering Platform to Assess Cellular Responses Ex Vivo', Advanced Science, 9, http://dx.doi.org/10.1002/advs.202103332

Journal articles | 2022

Saunus JM; De Luca XM; Northwood K; Raghavendra A; Hasson A; McCart Reed AE; Lim M; Lal S; Vargas AC; Kutasovic JR; Dalley AJ; Miranda M; Kalaw E; Kalita-de Croft P; Gresshoff I; Al-Ejeh F; Gee JMW; Ormandy C; Khanna KK; Beesley J; Chenevix-Trench G; Green AR; Rakha EA; Ellis IO; Nicolau DV; Simpson PT; Lakhani SR, 2022, 'Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer', npj Breast Cancer, 8, http://dx.doi.org/10.1038/s41523-022-00425-x

Journal articles | 2022

Zammit NW; McDowell J; Warren J; Muskovic W; Gamble J; Shi YC; Kaczorowski D; Chan CL; Powell J; Ormandy C; Brown D; Oakes SR; Grey ST, 2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.811525

Journal articles | 2021

Holliday H; Roden D; Junankar S; Wu SZ; Baker LA; Krisp C; Chan CL; McFarland A; Skhinas JN; Cox TR; Pal B; Huntington ND; Ormandy CJ; Carroll JS; Visvader J; Molloy MP; Swarbrick A, 2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072

Journal articles | 2021

Sun Y; Yang N; Utama FE; Udhane SS; Zhang J; Peck AR; Yanac A; Duffey K; Langenheim JF; Udhane V; Xia G; Peterson JF; Jorns JM; Nevalainen MT; Rouet R; Schofield P; Christ D; Ormandy CJ; Rosenberg AL; Chervoneva I; Tsaih SW; Flister MJ; Fuchs SY; Wagner KU; Rui H, 2021, 'NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abc8145

Journal articles | 2021

Valdés-Mora F; Salomon R; Gloss BS; Law AMK; Venhuizen J; Castillo L; Murphy KJ; Magenau A; Papanicolaou M; Rodriguez de la Fuente L; Roden DL; Colino-Sanguino Y; Kikhtyak Z; Farbehi N; Conway JRW; Sikta N; Oakes SR; Cox TR; O'Donoghue SI; Timpson P; Ormandy CJ; Gallego-Ortega D, 2021, 'Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype', Cell Reports, 35, http://dx.doi.org/10.1016/j.celrep.2021.108945

Journal articles | 2020

Baker LA; Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O'Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, 'Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer', Breast Cancer Research, 22, http://dx.doi.org/10.1186/s13058-020-01306-6

Journal articles | 2020

Castillo L; Young AIJ; Mawson A; Schafranek P; Steinmann AM; Nessem D; Parkin A; Johns A; Chou A; Law AMK; Lucas MC; Murphy KJ; Deng N; Gallego-Ortega D; Caldon CE; Timpson P; Pajic M; Ormandy CJ; Oakes SR, 2020, 'MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma', Oncogene, 39, pp. 1821 - 1829, http://dx.doi.org/10.1038/s41388-019-1091-0

Journal articles | 2020

Holliday H; Roden D; Junankar S; Wu S; Baker L; Krisp C; Chan C-L; McFarland A; Skhinas J; Cox T; Pal B; Huntington N; Ormandy C; Carroll J; Visvader J; Molloy M; Swarbrick A, 2020, 'Inhibitor of Differentiation 4 (ID4) represses myoepithelial differentiation of mammary stem cells through its interaction with HEB', , http://dx.doi.org/10.1101/2020.04.06.026963

Journal articles | 2020

Piggin CL; Roden DL; Law AMK; Molloy MP; Krisp C; Swarbrick A; Naylor MJ; Kalyuga M; Kaplan W; Oakes SR; Gallego-Ortega D; Clark SJ; Carroll JS; Bartonicek N; Ormandy CJ, 2020, 'ELF5 modulates the estrogen receptor cistrome in breast cancer', PLoS Genetics, 16, http://dx.doi.org/10.1371/journal.pgen.1008531

Journal articles | 2020

Teo WS; Holliday H; Karthikeyan N; Cazet AS; Roden DL; Harvey K; Konrad CV; Murali R; Varghese BA; Thankamony AP; Chan CL; McFarland A; Junankar S; Ye S; Yang J; Nikolic I; Shah JS; Baker LA; Millar EKA; Naylor MJ; Ormandy CJ; Lakhani SR; Kaplan W; Mellick AS; O'Toole SA; Swarbrick A; Nair R, 2020, 'Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.00552

Journal articles | 2019

Alexandrou S; George SM; Ormandy CJ; Lim E; Oakes SR; Elizabeth Caldon C, 2019, 'The proliferative and apoptotic landscape of basal-like breast cancer', International Journal of Molecular Sciences, 20, http://dx.doi.org/10.3390/ijms20030667

Journal articles | 2019

Castillo L; George S; Lin H-M; Yeung N; Mawson A; Young AI; Law AM; Hastings J; Gallego-Ortega D; Deng N; Croucher D; Swarbrick A; Horvath L; Ormandy CJ; Oakes SR, 2019, 'Flicking the switch off, targeting MCL-1 in the treatment of breast and prostate cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p038

Journal articles | 2019

Money A-M; Schaverin J; Aubel P; Neist E; Owens T; Swarbrick A; Taniuchi I; Ormandy CJ; Simpson PT; Naylor MJ, 2019, 'Novel role of CBF[beta] as a regulator of breast cancer phenotype, progression and metastasis', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p037

Journal articles | 2019

Valdes-Mora F; Salomon R; Gloss B; Law AMK; Castillo L; Murphy K; Venhuizen J; Magenau A; Papanicolau M; de la Fuente LR; Roden D; Colino-Sanguino Y; Kikhtyak Z; Farbehi N; Conway JRW; Oakes S; Sikta N; O’Donoghue S; Cox T; Timpson P; Ormandy C; Gallego-Ortega D, 2019, 'Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype', , http://dx.doi.org/10.1101/624890

Journal articles | 2019

Valdes-Mora F; Salomon R; Gloss B; Law AMK; Murphy K; Roden DL; Castillo L; Colino-Sanguino Y; Farbehi N; Conway J; Timpson P; Ormandy CJ; Gallego-Ortega D, 2019, 'Characterisation of developmental pathways that drive metastatic progression of breast cancer at single cell resolution', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p022

Journal articles | 2018

Baker L; Krisp C; Roden D; Holliday H; Wu S; Junankar S; Serandour A; Mohammed H; Nair R; Chan C-L; Yang J; Foreman N; Fitzpatrick B; Sankaranarayanan G; Law AMK; Ormandy C; Naylor M; McFarland A; Simpson P; Lakhani S; O'Toole S; Selinger C; Anderson L; Samimi G; Hacker N; Kaplan W; Carroll J; Molloy M; Swarbrick A, 2018, 'A novel role for the HLH protein Inhibitor of Differentiation 4 (ID4) in the DNA damage response in basal-like breast cancer.', BIORXIV, http://dx.doi.org/10.1101/281196

Journal articles | 2018

Hassanzadeh-Barforoushi A; Law AMK; Hejri A; Asadnia M; Ormandy CJ; Gallego-Ortega D; Ebrahimi Warkiani M, 2018, 'Static droplet array for culturing single live adherent cells in an isolated chemical microenvironment', Lab on a Chip, 18, pp. 2156 - 2166, http://dx.doi.org/10.1039/c8lc00403j

Journal articles | 2018

Valdes-Mora F; Handler K; Law AMK; Salomon R; Oakes SR; Ormandy CJ; Gallego-Ortega D, 2018, 'Single-cell transcriptomics in cancer immunobiology: The future of precision oncology', Frontiers in Immunology, 9, http://dx.doi.org/10.3389/fimmu.2018.02582

Journal articles | 2018

Young AIJ; Timpson P; Gallego-Ortega D; Ormandy CJ; Oakes SR, 2018, 'Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion', Cell Adhesion and Migration, 12, pp. 513 - 523, http://dx.doi.org/10.1080/19336918.2017.1393591

Journal articles | 2017

Law AMK; Lim E; Ormandy CJ; Gallego-Ortega D, 2017, 'Erratum: The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy (Endocrine-related cancer (2017) 24 4 (R123-R144) PII: ERC160404e)', Endocrine-related cancer, 24, pp. X1, http://dx.doi.org/10.1530/ERC-16-0404e

Journal articles | 2017

Law AMK; Lim E; Ormandy CJ; Gallego-Ortega D, 2017, 'The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy', Endocrine-Related Cancer, 24, pp. R123 - R144, http://dx.doi.org/10.1530/ERC-16-0404

Journal articles | 2017

Law AMK; Yin JXM; Castillo L; Young AIJ; Piggin C; Rogers S; Caldon CE; Burgess A; Millar EKA; O'Toole SA; Gallego-Ortega D; Ormandy CJ; Oakes SR, 2017, 'Andy's Algorithms: New automated digital image analysis pipelines for FIJI', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-15885-6

Journal articles | 2017

Nobis M; Herrmann D; Warren SC; Kadir S; Leung W; Killen M; Magenau A; Stevenson D; Lucas MC; Reischmann N; Vennin C; Conway JRW; Boulghourjian A; Zaratzian A; Law AM; Gallego-Ortega D; Ormandy CJ; Walters SN; Grey ST; Bailey J; Chtanova T; Quinn JMW; Baldock PA; Croucher PI; Schwarz JP; Mrowinska A; Zhang L; Herzog H; Masedunskas A; Hardeman EC; Gunning PW; del Monte-Nieto G; Harvey RP; Samuel MS; Pajic M; McGhee EJ; Johnsson AKE; Sansom OJ; Welch HCE; Morton JP; Strathdee D; Anderson KI; Timpson P, 2017, 'A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts', Cell Reports, 21, pp. 274 - 288, http://dx.doi.org/10.1016/j.celrep.2017.09.022

Journal articles | 2017

Oakes SR; Gallego-Ortega D; Stanford PM; Junankar S; Au WWY; Kikhtyak Z; von Korff A; Sergio CM; Law AMK; Castillo LE; Allerdice SL; Young AIJ; Piggin C; Whittle B; Bertram E; Naylor MJ; Roden DL; Donovan J; Korennykh A; Goodnow CC; O’Bryan MK; Ormandy CJ, 2017, 'A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactation', PLoS Genetics, 13, http://dx.doi.org/10.1371/journal.pgen.1007072

Journal articles | 2017

Vennin C; Chin VT; Warren SC; Lucas MC; Herrmann D; Magenau A; Melenec P; Walters SN; Del Monte-Nieto G; Conway JRW; Nobis M; Allam AH; McCloy RA; Currey N; Pinese M; Boulghourjian A; Zaratzian A; Adam AAS; Heu C; Nagrial AM; Chou A; Steinmann A; Drury A; Froio D; Giry-Laterriere M; Harris NLE; Phan T; Jain R; Weninger W; McGhee EJ; Whan R; Johns AL; Samra JS; Chantrill L; Gill AJ; Kohonen-Corish M; Harvey RP; Biankin AV; Evans TRJ; Anderson KI; Grey ST; Ormandy CJ; Gallego-Ortega D; Wang Y; Samuel MS; Sansom OJ; Burgess A; Cox TR; Morton JP; Pajic M; Timpson P, 2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, 9, http://dx.doi.org/10.1126/scitranslmed.aai8504

Journal articles | 2016

Erami Z; Herrmann D; Warren SC; Nobis M; McGhee EJ; Lucas MC; Leung W; Reischmann N; Mrowinska A; Schwarz JP; Kadir S; Conway JRW; Vennin C; Karim SA; Campbell AD; Gallego-Ortega D; Magenau A; Murphy KJ; Ridgway RA; Law AM; Walters SN; Grey ST; Croucher DR; Zhang L; Herzog H; Hardeman EC; Gunning PW; Ormandy CJ; Evans TRJ; Strathdee D; Sansom OJ; Morton JP; Anderson KI; Timpson P, 2016, 'Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue', Cell Reports, 14, pp. 152 - 167, http://dx.doi.org/10.1016/j.celrep.2015.12.020

Journal articles | 2016

Piggin CL; Roden DL; Gallego-Ortega D; Lee HJ; Oakes SR; Ormandy CJ, 2016, 'ELF5 isoform expression is tissue-specific and significantly altered in cancer', Breast Cancer Research, 18, http://dx.doi.org/10.1186/s13058-015-0666-0

Journal articles | 2016

Young AIJ; Law AMK; Castillo L; Chong S; Cullen HD; Koehler M; Herzog S; Brummer T; Lee EF; Fairlie WD; Lucas MC; Herrmann D; Allam A; Timpson P; Watkins DN; Millar EKA; O'Toole SA; Gallego-Ortega D; Ormandy CJ; Oakes SR, 2016, 'MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib', Breast Cancer Research, 18, http://dx.doi.org/10.1186/s13058-016-0781-6

Journal articles | 2015

Gallego-Ortega D; Ledger A; Roden DL; Law AMK; Magenau A; Kikhtyak Z; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Herrmann D; Salomon R; Young AIJ; Lee BY; Sergio CM; Kaplan W; Piggin C; Conway JRW; Rabinovich B; Millar EKA; Oakes SR; Chtanova T; Swarbrick A; Naylor MJ; O’Toole S; Green AR; Timpson P; Gee JMW; Ellis IO; Clark SJ; Ormandy CJ, 2015, 'ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells', PLoS Biology, 13, http://dx.doi.org/10.1371/journal.pbio.1002330

Journal articles | 2015

Junankar S; Baker LA; Roden DL; Nair R; Elsworth B; Gallego-Ortega D; Lacaze P; Cazet A; Nikolic I; Teo WS; Yang J; McFarland A; Harvey K; Naylor MJ; Lakhani SR; Simpson PT; Raghavendra A; Saunus J; Madore J; Kaplan W; Ormandy C; Millar EKA; O'Toole S; Yun K; Swarbrick A, 2015, 'ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype', NATURE COMMUNICATIONS, 6, http://dx.doi.org/10.1038/ncomms7548

Journal articles | 2015

Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling A-L; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O'Bryan MK, 2015, 'Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.', PLoS Genet, 11, pp. e1005782, http://dx.doi.org/10.1371/journal.pgen.1005782

Journal articles | 2015

Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling AL; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O’Bryan MK, 2015, 'HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005620

Journal articles | 2015

Liu Y; DeBoer K; de Kretser DM; O’Donnell L; O’Connor AE; Merriner DJ; Okuda H; Whittle B; Jans DA; Efthymiadis A; McLachlan RI; Ormandy CJ; Goodnow CC; Jamsai D; O’Bryan MK, 2015, 'LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005090

Journal articles | 2014

Ali NA; Wu J; Hochgräfe F; Chan H; Nair R; Ye S; Zhang L; Lyons RJ; Pinese M; Lee HC; Armstrong N; Ormandy CJ; Clark SJ; Swarbrick A; Daly RJ, 2014, 'Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways', Breast Cancer Research, 16, http://dx.doi.org/10.1186/s13058-014-0437-3

Journal articles | 2014

Byrne FL; Yang L; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11

Journal articles | 2014

Hilton HN; Doan TB; Dinny Graham J; Oakes SR; Silvestri A; Santucci N; Kantimm S; Huschtscha LI; Ormandy CJ; Funder JW; Simpson ER; Kuczek ES; Leedman PJ; Tilley WD; Fuller PJ; Muscat GEO; Clarke CL, 2014, 'Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease', Oncotarget, 5, pp. 8651 - 8664, http://dx.doi.org/10.18632/oncotarget.2354

Journal articles | 2014

Oakes SR; Gallego-Ortega D; Ormandy CJ, 2014, 'The mammary cellular hierarchy and breast cancer', Cellular and Molecular Life Sciences, 71, pp. 4301 - 4324, http://dx.doi.org/10.1007/s00018-014-1674-4

Journal articles | 2014

Owens TW; Rogers RL; Best SA; Ledger A; Mooney AM; Ferguson A; Shore P; Swarbrick A; Ormandy CJ; Simpson PT; Carroll JS; Visvader JE; Naylor MJ, 2014, 'Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer', Cancer Research, 74, pp. 5277 - 5286, http://dx.doi.org/10.1158/0008-5472.CAN-14-0053

Journal articles | 2013

Gallego-Ortega D; Oakes SR; Lee HJ; Piggin CL; Ormandy CJ, 2013, 'ELF5, normal mammary development and the heterogeneous phenotypes of breast cancer', BREAST CANCER MANAGEMENT, 2, pp. 489 - 498, http://dx.doi.org/10.2217/BMT.13.50

Journal articles | 2013

Jamsai D; Clark BJ; Smith SJ; Whittle B; Goodnow CC; Ormandy CJ; O'Bryan MK, 2013, 'A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0077311

Journal articles | 2013

Lee HJ; Gallego-Ortega D; Ledger A; Schramek D; Joshi P; Szwarc MM; Cho C; Lydon JP; Khokha R; Penninger JM; Ormandy CJ, 2013, 'Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells', Development (Cambridge), 140, pp. 1397 - 1401, http://dx.doi.org/10.1242/dev.088948

Journal articles | 2013

Moleirinho S; Chang N; Sims AM; Tilston-lunel AM; Angus L; Steele A; Angus L; Barnett S; Ormandy CJ; Faratian D; Gunn-moore FJ; Reynolds PA, 2013, 'KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals', Oncogene, 32, pp. 1821 - 1830, http://dx.doi.org/10.1038/onc.2012.196

Journal articles | 2013

Nair R; Roden DL; Teo WS; McFarland A; Junankar S; Ye S; Nguyen A; Yang J; Nikolic I; Hui M; Morey A; Shah J; Pfefferle AD; Usary J; Selinger C; Baker LA; Armstrong N; Cowley MJ; Naylor MJ; Ormandy CJ; Lakhani SR; Herschkowitz JI; Perou CM; Kaplan W; O'Toole SA; Swarbrick A, 2013, 'c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer', Oncogene, http://dx.doi.org/10.1038/onc.2013.368

Journal articles | 2013

O'Bryan MK; Clark BJ; McLaughlin EA; D'Sylva RJ; O'Donnell L; Wilce JA; Sutherland J; O'Connor AE; Whittle B; Goodnow CC; Ormandy CJ; Jamsai D, 2013, 'RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility', PLoS Genetics, 9, http://dx.doi.org/10.1371/journal.pgen.1003628

Journal articles | 2013

Ortiz-padilla C; Gallego-ortega D; Browne B; Hochgrafe F; Caldon CE; Lyons R; Croucher DR; Rickwood D; Ormandy CJ; Brummer T; Daly RJ, 2013, 'Functional characterization of cancer-associated Gab1 mutations', Oncogene, 32, pp. 2696 - 2702, http://dx.doi.org/10.1038/onc.2012.271

Journal articles | 2013

Stone A; Cowley MJ; Valdes-Mora F; McCloy RA; Sergio CM; Gallego-Ortega D; Caldon CE; Ormandy CJ; Biankin AV; Gee JMW; Nicholson RI; Print CG; Clark SJ; Musgrove EA, 2013, 'BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer', Molecular Cancer Therapeutics, 12, pp. 1874 - 1885, http://dx.doi.org/10.1158/1535-7163.MCT-13-0012

Journal articles | 2012

Kalyuga M; Gallego-Ortega D; Lee H; Roden DL; Cowley MJ; Caldon CE; Stone A; Allerdice SL; Valdes-Mora F; Rosalind launchbury R; Statham A; Armstrong NJ; Alles MC; Adelaide young A; Egger A; Au W; Piggin CL; Evans C; Ledger A; Brummer T; Oakes SR; Kaplan W; Gee JMW; Robert i nicholson RI; Sutherland RL; Swarbrick A; Naylor MJ; Clark SJ; Carroll JS; Ormandy CJ, 2012, 'ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer', PLoS Biology, 10, pp. e1001461, http://dx.doi.org/10.1371/journal.pbio.1001461

Journal articles | 2012

Lee H; Ormandy CJ, 2012, 'Elf5, hormones and cell fate', Trends in Endocrinology and Metabolism, 23, pp. 292 - 298, http://dx.doi.org/10.1016/j.tem.2012.02.006

Journal articles | 2012

Lee H; Ormandy CJ, 2012, 'Interplay between progesterone and prolactin in mammary development and implications for breast cancer', Molecular and Cellular Endocrinology, 357, pp. 101 - 107, http://dx.doi.org/10.1016/j.mce.2011.09.020

Journal articles | 2012

Lo JCY; Jamsai D; O'connor A; Borg C; Clark B; Whisstock J; Field M; Adams V; Ishikawa T; Aitken R; Whittle B; Goodnow CC; Ormandy CJ; O'bryan M, 2012, 'RAB-Like 2 Has an Essential Role in Male Fertility, Sperm Intra-Flagellar Transport, and Tail Assembly', PLoS Genetics, 8, pp. e1002969, http://dx.doi.org/10.1371/journal.pgen.1002969

Journal articles | 2012

O''Donnell L; Rhodes D; Smith SJ; Merriner DJ; Borg C; Whittle B; O'connor A; Smith L; Mcnally FJ; de Kretser D; Goodnow CC; Ormandy CJ, 2012, 'An essential role for katanin p80 and microtubule severing in male gamete production', PLoS Genetics, 8, pp. e1002698, http://dx.doi.org/10.1371/journal.pgen.1002698

Journal articles | 2011

Lee HJ; Hinshelwood R; Bouras T; Gallego-Ortega D; Valdes-Mora F; Blazek K; Visvader JE; Clark SJ; Ormandy CJ, 2011, 'Lineage specific methylation of the Elf5 promoter in mammary epithelial cells', Stem Cells, 29, pp. 1611 - 1619, http://dx.doi.org/10.1002/stem.706

Journal articles | 2011

O'Toole S; Machalek DA; Shearer R; Millar E; Nair R; Schofield PR; McLeod D; Cooper CE; Mcneil CM; Mcfarland A; Nguyen A; Ormandy CJ; Qiu M; Rabinovich B; Martelotto L; Vu D; Hannigan GE; Musgrove EA; Christ DU; Sutherland RL; Watkins DJ; Swarbrick A, 2011, 'Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer', Cancer research, 71, pp. 4002 - 4014, http://dx.doi.org/10.1158/0008-5472.CAN-10-3738

Journal articles | 2010

Bhandari M; Thomas A; Hussey DJ; Xin L; Jaya SP; Woods C; Schloithe AC; Mayne GC; Carati CJ; Toouli J; Ormandy CJ; Saccone GTP, 2010, 'Galanin mediates the pathogenesis of cerulein-induced acute pancreatitis in the mouse', Pancreas, 39, pp. 182 - 187, http://dx.doi.org/10.1097/MPA.0b013e3181bdc152

Journal articles | 2010

Chan C; Liu X; Ensslin MA; Dillehay DL; Ormandy CJ; Sohn P; Serra R; Ye K, 2010, 'PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development', European Molecular Biology Organization, 29, pp. 956 - 968, http://dx.doi.org/10.1038/emboj.2009.406

Journal articles | 2010

Jamsai D; Smith SJ; O'Connor AE; Merriner DJ; Borg C; Clark B; Adams V; Ormandy CJ; O'Bryan MK, 2010, '169. THE MECHANISM OF SPERMATID MATURATION - A LINK TO TUMOUR SUPPRESSION', Reproduction, Fertility and Development, 22, pp. 87 - 87, http://dx.doi.org/10.1071/srb10abs169

Journal articles | 2010

Menzies KK; Lee HJ; Lefevre C; Ormandy CJ; Macmillan KL; Nicholas KR, 2010, 'Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants', Functional and Integrative Genomics, 10, pp. 87 - 95, http://dx.doi.org/10.1007/s10142-009-0140-0

Journal articles | 2010

Schramek D; Leibbrandt A; Sigl V; Kenner L; Pospisilik JA; Lee HJ; Hanada R; Joshi PA; Aliprantis A; Glimcher L; Pasparakis M; Khokha R; Ormandy CJ; Widschwendter M; Schett G; Penninger JM, 2010, 'Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer', Nature, 468, pp. 98 - 102

Journal articles | 2010

Zardawi SJ; Zardawi I; Mcneil CM; Millar E; Mcleod D; Morey AL; Crea P; Murphy NC; Pinese M; Lopez-Knowles E; Oakes SR; Ormandy CJ; Qiu MR; Hamilton A; Spillane AJ; Lee CS; Sutherland RL; Musgrove EA; O'Toole S, 2010, 'High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype', Histopathology, 56, pp. 286 - 296, http://dx.doi.org/10.1111/j.1365-2559.2009.03475.x

Journal articles | 2009

Alles MC; Gardiner-Garden M; Nott DJ; Foekens J; Wang Y; Sutherland RL; Musgrove EA; Ormandy CJ, 2009, 'Meta-analysis and gene set enrichment relative to ER status reveal elevated activity of MYC and E2F in the `Basal` breast cancer subgroup', PLoS One, 4

Journal articles | 2008

Hilton HN; Stanford PM; Harris J; Oakes SR; Kaplan W; Daly RJ; Ormandy CJ, 2008, 'KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling', Biochimica et Biophysica ACTA - Molecular Cell Research, 1783, pp. 383 - 393, http://dx.doi.org/10.1016/j.bbamcr.2007.12.007

Journal articles | 2008

Musgrove EA; Sergio CM; Anderson LR; Inman CK; Mcneil CM; Alles MC; Gardiner-Garden M; Ormandy CJ; Butt A; Sutherland RL, 2008, 'Identification of downstream targets of estrogen and c-myc in breast cancer cells', , pp. 445 - 451

Journal articles | 2008

Musgrove EA; Sergio CM; Loi S; Inman CK; Anderson LR; Alles MC; Pinese M; Caldon CE; Schutte J; Gardiner-Garden M; Ormandy CJ; McArthur G; Butt A; Sutherland RL, 2008, 'Identification of functional networks of estrogen-and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer', PLoS One, 3, pp. 2987 - 2995

Journal articles | 2008

Oakes SR; Naylor MJ; Asselin-Labat M; Blazek K; Gardiner-Garden M; Hilton HN; Kazlauskas M; Pritchard M; Chodosh L; Pfeffer P; Lindeman GJ; Visvader J; Ormandy CJ, 2008, 'The Ets transcription factor Elf5 specifies mammary alveolar cell fate', Genes and Development, 22, pp. 581 - 586, http://dx.doi.org/10.1101/gad.1614608

Journal articles | 2008

Oakes SR; Rogers R; Naylor MJ; Ormandy CJ, 2008, 'Prolactin regulation of mammary gland development', Journal of Mammary Gland Biology and Neoplasia, 13, pp. 13 - 28, http://dx.doi.org/10.1007/s10911-008-9069-5

Journal articles | 2008

Ramanathan P; Martin I; Gardiner-Garden M; Thomson P; Taylor R; Ormandy CJ; Moran C; Williamson P, 2008, 'Transcriptome analysis identifies pathways associated with enhanced maternal performance in QSi5 mice', BMC Genomics, 9, pp. 1 - 13, http://dx.doi.org/10.1186/1471-2164-9-197

Journal articles | 2007

Naylor MJ; Ormandy CJ, 2007, 'Gata-3 and mammary cell fate', Breast Cancer Research, 9

Journal articles | 2007

Oakes SR; Robertson FG; Kench JG; Gardiner-Garden M; Wand MP; Green JE; Ormandy CJ, 2007, 'Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions', Oncogene, 26, pp. 543 - 553

Journal articles | 2006

Craven AJ; Nixon AJ; Ashby MG; Ormandy CJ; Blazek K; Wilkins RJ; Pearson AJ, 2006, 'Prolactin delays hair regrowth in mice', Journal of Endocrinology, 191, pp. 415 - 425

Journal articles | 2006

Harris J; Stanford PM; Sutherland K; Oakes SR; Naylor MJ; Robertson F; Blazek K; Kazlauskas M; Hilton HN; Wittlin S; Alexander WS; Lindeman GJ; Visvader J; Ormandy CJ, 2006, 'Socs2 and Elf5 mediate prolactin-induced mammary gland development', Molecular Endocrinology, 20, pp. 1177 - 1187

Journal articles | 2006

McNeil CM; Sergio CM; Anderson LR; Inman CK; Eggleton SA; Murphy NC; Millar EKA; Crea P; Kench JG; Alles MC; Gardiner-Garden M; Ormandy CJ; Butt AJ; Henshall SM; Musgrove EA; Sutherland RL, 2006, 'c-Myc overexpression and endocrine resistance in breast cancer', Journal of Steroid Biochemistry and Molecular Biology, 102, pp. 147 - 155, http://dx.doi.org/10.1016/j.jsbmb.2006.09.028

Journal articles | 2006

Mcneil CM; Anderson LR; Inman CK; Eggleton SA; Murphy NC; Millar E; Crea P; Kench JG; Alles MC; Gardiner-Garden M; Ormandy CJ; Butt A; Henshall SM; Musgrove EA; Sutherland RL; Sergio CM, 2006, 'c-Myc overexpression and endocrine resistance in breast cancer', Journal of Steroid Biochemistry and Molecular Biology, 18, pp. 284 - 289

Journal articles | 2006

Oakes SR; Hilton HN; Ormandy CJ, 2006, 'Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium', Breast Cancer Research, 8

Journal articles | 2005

Menzies KK; Macmillan KL; Nicholas KR; Lefevre C; Ormandy C, 2005, '281. The role of insulin in milk protein synthesis', Reproduction, Fertility and Development, 17, pp. 117 - 117, http://dx.doi.org/10.1071/srb05abs281

Journal articles | 2005

Naylor MJ; Oakes SR; Gardiner-Garden M; Harris J; Blazek K; Ho TW; Li F; Wynick D; Walker AM; Ormandy CJ, 2005, 'Transcriptional changes underlying the secretory activation phase of mammary gland development', Molecular Endocrinology, 19, pp. 1868 - 1883

Journal articles | 2005

Nilsson L; Binart N; Bohlooly-Y M; Bramnert M; Egecioglu E; Kindblom J; Kelly PA; Kopchick J; Ormandy CJ; Ling C; Billig H, 2005, 'Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue', Biochemical and Biophysical Research Communications, 331, pp. 1120 - 1126, http://www.sciencedirect.com/science/article/B6WBK-4FYGBBM-1/2/53f2f3ba0a766cd5714b305e659026fd

Journal articles | 2005

Ormandy C; Goffin V, 2005, 'Cancer', Drug Discovery Today: Disease Models, 2, http://dx.doi.org/10.1016/j.ddmod.2005.05.022

Journal articles | 2005

Ormandy CJ, 2005, 'Review of: Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone', Breast Cancer Online, 8, http://dx.doi.org/10.1017/s1470903105004475

Journal articles | 2005

Zhou J; Chehab R; Tkalcevic J; Naylor MJ; Harris J; Wilson T; Tsao S; Tellis I; Zavarsek S; Xu D; Lapinskas E; Visvader J; Lindeman GJ; Thomas R; Ormandy CJ; Hertzog P; Kola I; Pritchard M, 2005, 'Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation', European Molecular Biology Organization, 24, pp. 635 - 644

Journal articles | 2004

Cooney GJ; Lyons RJ; Crew A; Jensen T; Molero JC; Mitchell CJ; Biden TJ; Ormandy CJ; James DE; Daly et A, 2004, 'Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice', EMBO Journal, 23, pp. 582 - 593, http://www.sciencedirect.com/science/article/B6WVB-4C6S53N-1D7/2/8969638193550a0dce7725a099aba822

Journal articles | 2004

Harris J; Stanford PM; Oakes SR; Ormandy CJ, 2004, 'Prolactin and the prolactin receptor: new targets of an old hormone', Annals of Medicine, 36, pp. 414 - 425, http://www.sciencedirect.com/science/article/B6WVB-4DPTTDJ-115/2/64c9f2829ad0aa962efbb9ba7f7f6f0c

Journal articles | 2004

Musgrove EA; Davison EA; Ormandy CJ, 2004, 'Role of the CDK Inhibitor p27 (Kip1) in Mammary Development and Carcinogenesis: Insights from Knockout Mice', Journal of Mammary Gland Biology and Neoplasia, 9, pp. 55 - 66, http://www.sciencedirect.com/science/article/B6WVB-4C82RMK-3D1/2/72b5e4398e846ea1a8f5ab7fa97d561a

Journal articles | 2004

Saunders DN; Hird S; Withington SL; Dunwoodie SL; Henderson M; Biben C; Sutherland RL; Ormandy CJ; Watts CK, 2004, 'Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion', Molecular and Cellular Biology, 24, pp. 7225 - 7234, http://dx.doi.org/10.1128/MCB.24.16.7225-7234.2004

Journal articles | 2004

Saunders DN; Hird SL; Withington SL; Dunwoodie SL; Henderson MJ; Biben C; Sutherland RL; Ormandy CJ; Watts CKW, 2004, 'Erratum: Edd, the murine ortholog of the hyperplastic discs (hyd) gene, is essential for yolk sac vascularization and chorioallantoic fusion (Molecular and Cellular Biology (2004) 24: 16 (7225-7234))', Molecular and Cellular Biology, 24, pp. 9262, http://dx.doi.org/10.1128/MCB.24.20.9262.2004

Journal articles | 2003

Davison EA; Lee CM; Naylor MJ; Oakes SR; Sutherland RL; Henninghausen L; Ormandy CJ; Musgrove EA, 2003, 'The Cyclin-Dependent Kinase inhibitor p27 (Kip1) regulates both DNA synthesis and apoptosis in mammary epithelium but is not required for its functional development during pregnancy.', Molecular Endocrinology, 17, pp. 2436 - 2447

Journal articles | 2003

Gass S; Harris J; Ormandy CJ; Brisken C, 2003, 'Using gene expression arrays to elucidate transcriptional profiles underlying prolactin function', Journal of Mammary Gland Biology and Neoplasia, 8, pp. 269 - 285

Journal articles | 2003

Hovey RC; Harris J; Hadsell DL; Lee A; Ormandy CJ; Vonderhaar BK, 2003, 'Local insulin-like growth factor-II mediates prolactin-induced mammary gland development', Molecular Endocrinology, 17, pp. 460 - 471

Journal articles | 2003

Kindblom J; Dillner K; Sahlin L; Robertson F; Ormandy CJ; Tornell J; Wennbo H, 2003, 'Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin', Endocrinology, 144, pp. 2269 - 2278

Journal articles | 2003

Naylor MJ; Ginsburg E; Iismaa T; Vonderhaar BK; Wynick D; Ormandy CJ, 2003, 'The neuropeptide galanin augments lobuloalveolar development', The Journal of Biological Chemistry, 278, pp. 29145 - 29152

Journal articles | 2003

Naylor MJ; Lockerfeer JA; Horseman NJ; Ormandy CJ, 2003, 'Prolactin regulates mammary epithelial cell proliferation via autocrine/paracrine mechanism', Endocrine, 20, pp. 111 - 114

Journal articles | 2003

Ormandy CJ; Musgrove EA; Hui R; Daly RJ; Sutherland RL, 2003, 'Cyclin D1, EMS1 and 11q13 amplication in breast cancer', Breast Cancer Research and Treatment, 78, pp. 323 - 335

Journal articles | 2003

Robertson F; Harris J; Naylor MJ; Oakes S; Kindblom J; Dillner K; Wennbo H; Tornell J; Kelly PA; Green J; Ormandy CJ, 2003, 'Prostate development and carcinogenesis in prolactin receptor knockout mice', Endocrinology, 144, pp. 3196 - 3205

Journal articles | 2002

Grimm SL; Seagroves TN; Kabotyanski EB; Hovey RC; Vonderhaar BK; Lydon JP; Miyoshi K; Hennighausen L; Ormandy CJ; Lee AV; Stull MA; Wood TL; Rosen JM, 2002, 'Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development', Molecular Endocrinology, 16, pp. 2675 - 2691, http://dx.doi.org/10.1210/me.2002-0239

Journal articles | 2002

Kelly PA; Bachelot A; Kedzia C; Hennighausen L; Ormandy CJ; Kopchick JJ; Binart N, 2002, 'The role of prolactin and growth hormone in mammary gland development', Molecular and Cellular Endocrinology, 197, pp. 127 - 131, http://dx.doi.org/10.1016/S0303-7207(02)00286-1

Journal articles | 2002

Naylor MJ; Ormandy CJ, 2002, 'Mouse strain-specific patterns of mammary epithelial ductal side branching are elicited by stromal factors', Developmental Dynamics, 225, pp. 100 - 105, http://dx.doi.org/10.1002/dvdy.10133

Journal articles | 2002

Sainsbury A; Schwarzer C; Couzens M; Jenkins A; Oakes SR; Ormandy CJ; Herzog H, 2002, 'Y4 receptor knockout rescues fertility in ob/ob mice', Genes and Development, 16, pp. 1077 - 1088, http://dx.doi.org/10.1101/gad.979102

Journal articles | 2001

Craven AJ; Ormandy CJ; Robertson FG; Wilkins RJ; Kelly PA; Nixon AJ; Pearson AJ, 2001, 'Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice*', Endocrinology, 142, pp. 2533 - 2539, http://dx.doi.org/10.1210/endo.142.6.8179

Journal articles | 2001

Craven AJ; Ormandy CJ; Robertson FG; Wilkins RJ; Kelly PA; Nixon AJ; Pearson AJ, 2001, 'Prolactin signaling influences the timing mechanism of the hair follicle: analysis of molting cycles in prolactin receptor knockout mice.', Endocrinology, 142, pp. 2533 - 2539

Journal articles | 2001

Linderman GJ; Wittlin S; Naylor MJ; Santamaria M; Zhang J; Starr R; Hilton D; Alexander WS; Ormandy CJ; Visvader J, 2001, 'SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor deficient mice.', Genes and Development, 15, pp. 1631 - 1639

Journal articles | 2001

McClellan KA; Robertson FG; Kindblom J; Wennbo H; Tornell J; Bouchard B; Kelly PA; Ormandy CJ, 2001, 'Investigation of the role of prolactin in the development and function of the lacrimal and Harderian glands using genetically modified mice', Investigative Ophthalmology and Visual Science, pp. 23 - 30

Journal articles | 2000

Binart N; Helloco C; Ormandy CJ; Barra J; Cle Ment-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of Preimplantatory Egg Development and Embryo Implantation in Prolactin Receptor-Deficient Mice after Progesterone Administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Journal articles | 2000

Binart N; Helloco C; Ormandy CJ; Barra J; Clément-Lacroix P; Baran N; Kelly PA, 2000, 'Rescue of preimplantatory egg development and embryo implantation in prolactin receptor-deficient mice after progesterone administration.', Endocrinology, 141, pp. 2691 - 2697, http://dx.doi.org/10.1210/endo.141.7.7568

Journal articles | 2000

Binart N; Ormandy CJ; Kelly PA, 2000, 'Mammary gland development and the prolactin receptor', Advances in Experimental Medicine and Biology, 480, pp. 85 - 92

Journal articles | 1999

Bouchard B; Ormandy CJ; Di Santo JP; Kelly PA, 1999, 'Immune system development and function in prolactin receptor-deficient mice', Journal of Immunology, 163, pp. 576 - 582

Journal articles | 1999

Brisken C; Kaur S; Chavarria TE; Binart N; Sutherland RL; Weinberg RA; Kelly P; Ormandy CJ, 1999, 'Prolactin controls mammary gland development via direct and indirect mechanisms', Developmental Biology, pp. 96 - 106

Journal articles | 1999

Cle Ment-Lacroix P; Ormandy C; Lepescheux LN; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin: Analysis of Bone Formation in Prolactin Receptor Knockout Mice* *This work was supported in part by grants from Hoechst Marion Roussel, Inc.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Journal articles | 1999

Clement-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts Are a New Target for Prolactin', Obstetrical & Gynecological Survey, 54, pp. 383 - 384, http://dx.doi.org/10.1097/00006254-199906000-00018

Journal articles | 1999

Clément-Lacroix P; Ormandy C; Lepescheux L; Ammann P; Damotte D; Goffin V; Bouchard B; Amling M; Gaillard-Kelly M; Binart N; Baron R; Kelly PA, 1999, 'Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice.', Endocrinology, 140, pp. 96 - 105, http://dx.doi.org/10.1210/endo.140.1.6436

Journal articles | 1999

Goffin V; Binart N; Clément-Lacroix P; Bouchard B; Bole-Feysot C; Edery M; Lucas BK; Touraine P; Pezet A; Maaskant R; Pichard C; Helloco C; Baran N; Favre H; Bernichtein S; Allamando A; Ormandy C; Kelly PA, 1999, 'From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models', Genetic Analysis - Biomolecular Engineering, 15, pp. 189 - 201, http://dx.doi.org/10.1016/S1050-3862(99)00025-X

Journal articles | 1998

Goffin V; Bouchard B; Ormandy CJ; Weimann E; Ferrag F; Touraine P; Bole-Feysot C; Maaskant RA; Clement-Lacroix P; Edery M; Binart N; Kelly PA, 1998, 'Prolactin: A hormone at the crossroads of neuroimmunoendocrinology', Annals of the New York Academy of Sciences, 840, pp. 498 - 509, http://dx.doi.org/10.1111/j.1749-6632.1998.tb09588.x

Journal articles | 1998

Kelly PA; Ormandy CJ; Bôle-Feysot C; Maaskant R; Freemark M; Binart N, 1998, 'Prolactin receptors and embryonic development: Gene expression and knockout studies', Placenta, 19, pp. 13 - 21, http://dx.doi.org/10.1016/s0143-4004(98)80003-9

Journal articles | 1998

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null Mutation of the Prolactin Receptor Gene Produces a Defect in Maternal Behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Journal articles | 1998

Lucas BK; Ormandy CJ; Binart N; Bridges RS; Kelly PA, 1998, 'Null mutation of the prolactin receptor gene produces a defect in maternal behavior', Endocrinology, 139, pp. 4102 - 4107, http://dx.doi.org/10.1210/endo.139.10.6243

Journal articles | 1998

Ormandy CJ; Binart N; Helloco C; Kelly PA, 1998, 'Mouse prolactin receptor gene: Genomic organization reveals alternative promoter usage and generation of isoforms via alternative 3'-exon splicing', DNA and Cell Biology, 17, pp. 761 - 770, http://dx.doi.org/10.1089/dna.1998.17.761

Journal articles | 1998

Ormandy CJ; Hui R; Sutherland RL, 1998, 'Galanin and 11q13 amplification in human breast cancer', Biotech Lab Int, pp. 14 - 16

Journal articles | 1998

Ormandy CJ; Lee CC; Ormandy HF; Fantl V; Shine J; Peters G; Sutherland RL, 1998, 'Amplification, expression and steroid regulation of the preprogalanin gene in human breast cancer', Cancer research, pp. 1353 - 1357

Journal articles | 1998

Wynick D; Small CJ; Bacon A; Holmes FE; Norman M; Ormandy CJ; Kilic E; Kerr NCH; Ghatei M; Talamantes F; Bloom SR; Pachnis V, 1998, 'Galanin regulates prolactin release and lactotroph proliferation', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 12671 - 12676, http://dx.doi.org/10.1073/pnas.95.21.12671

Journal articles | 1997

Bignon C; Binart N; Ormandy C; Schuler LA; Kelly PA; Djiane J, 1997, 'Long and short forms of the ovine prolactin receptor: cDNA cloning and genomic analysis reveal that the two forms arise by different alternative splicing mechanisms in ruminants and in rodents', Journal of Molecular Endocrinology, 19, pp. 109 - 120, http://dx.doi.org/10.1677/jme.0.0190109

Journal articles | 1997

Binart N; Ormandy C; Kelly PA, 1997, 'Le récepteur de la prolactine : une molécule-clé de la reproduction ?', médecine/sciences, 13, pp. 734 - 734, http://dx.doi.org/10.4267/10608/451

Journal articles | 1997

Ormandy CJ; Binart N; Kelly PA, 1997, 'Mammary gland development in prolactin receptor knockout mice.', Journal of mammary gland biology and neoplasia, 2, pp. 355 - 364, http://dx.doi.org/10.1023/A:1026395229025

Journal articles | 1997

Ormandy CJ; Camus A; Barra J; Damotte D; Lucas B; Buteau H; Edery M; Brousse N; Babinet C; Binart N; Kelly PA, 1997, 'Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse', Genes and Development, 11, pp. 167 - 178, http://dx.doi.org/10.1101/gad.11.2.167

Journal articles | 1997

Ormandy CJ; Hall R; Manning DL; Robertson JF; Blamey RW; Kelly P; Nicholson RI; Sutherland RL, 1997, 'Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in Breast cancer', Journal of Clinical Endocrinology and Metabolism, pp. 3692 - 3699

Journal articles | 1996

Lee CSL; DeFazio A; Ormandy CJ; Sutherland RL, 1996, 'Inverse regulation of oestrogen receptor and epidermal growth factor receptor genbe expression in MCF-7 breast cancer cells treated with phorbol ester', Journal of Steroid Biochemistry and Molecular Biology, 58, pp. 267 - 275, http://dx.doi.org/10.1016/0960-0760(96)00039-8

Journal articles | 1996

Møldrup A; Ormandy C; Nagano M; Murthy K; Banville D; Tronche F; Kelly PA, 1996, 'Differential promoter usage in prolactin receptor gene expression: hepatocyte nuclear factor 4 binds to and activates the promoter preferentially active in the liver.', Mol Endocrinol, 10, pp. 661 - 671, http://dx.doi.org/10.1210/mend.10.6.8776726

Journal articles | 1995

Manning DL; McClelland RA; Knowlden JM; Bryant S; Gee JMW; Green CD; Robertson JF; Blamey RW; Sutherland RL; Ormandy CJ; Nicholson RI, 1995, 'Differential expression of oestrogen regulated genes in breast cancer', Acta Oncologica, 34, pp. 641 - 646, http://dx.doi.org/10.3109/02841869509094041

Journal articles | 1994

Kelly PA; Edery M; Finidori J; Postel-Vinay MC; Gougon L; Ali S; Dinerstein H; Sotiropoulos A; Lochnan H; Ferrag F; Lebrun JJ; Ormandy C; Buteau H; Esposito N; Vincent V; Möldrup A, 1994, 'Receptor Domains Involved in Signal Transduction of Prolactin and Growth Hormone', Proceedings of the Society for Experimental Biology and Medicine, 206, pp. 280 - 283, http://dx.doi.org/10.3181/00379727-206-43759

Journal articles | 1993

Ormandy CJ; Lee CSL; Kelly PA; Sutherland RL, 1993, 'Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12‐O‐tetradecanoylphorbol‐13‐acetate in human breast cancer cells', Journal of Cellular Biochemistry, 52, pp. 47 - 56, http://dx.doi.org/10.1002/jcb.240520108

Journal articles | 1993

Ormandy CJ; Sutherland RL, 1993, 'At the cutting edge - Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Journal articles | 1993

Ormandy CJ; Sutherland RL, 1993, 'Mechanisms of prolactin receptor regulation in mammary gland', Molecular and Cellular Endocrinology, 91, http://dx.doi.org/10.1016/0303-7207(93)90247-H

Journal articles | 1993

Roman SD; Clarke CL; Ormandy CJ, 1993, 'Estradiol Induction of Retinoic Acid Receptors in Human Breast Cancer Cells', Cancer Research, 53, pp. 5940 - 5945

Journal articles | 1992

Ormandy CJ; Clarke CL; Kelly PA; Sutherland RL, 1992, 'Androgen regulation of prolactin‐receptor gene expression in MCF‐7 and MDA‐MB‐453 human breast cancer cells', International Journal of Cancer, 50, pp. 777 - 782, http://dx.doi.org/10.1002/ijc.2910500519

Journal articles | 1992

Ormandy CJ; De Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Journal articles | 1992

Ormandy CJ; Graham J; Kelly PA; Clarke CL; Sutherland RL, 1992, 'The Effect of Progestins on Prolactin Receptor Gene Transcription in Human Breast Cancer Cells', DNA and Cell Biology, 11, pp. 721 - 726, http://dx.doi.org/10.1089/dna.1992.11.721

Journal articles | 1992

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells', Biochemical and Biophysical Research Communications, 182, pp. 740 - 745, http://dx.doi.org/10.1016/0006-291X(92)91794-Q

Journal articles | 1992

Ormandy CJ; de Fazio A; Kelly PA; Sutherland RL, 1992, 'Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells.', Endocrinology, 131, pp. 982 - 984, http://dx.doi.org/10.1210/endo.131.2.1639037

Journal articles | 1990

Ormandy CJ; Clarke CL; Sutherland RL, 1990, 'Solubilization and characterization of a lactogenic receptor from human placental chorion membranes', Journal of Cellular Biochemistry, 43, pp. 1 - 15, http://dx.doi.org/10.1002/jcb.240430102

Journal articles | 1988

Teh TC; Ormandy CJ; Surus AS; Sutherland RL; Chapman GE, 1988, 'Human growth hormone binds to lactogenic receptors in bovine, ovine and rat adrenals', Hormone and Metabolic Research, 20, pp. 278 - 281, http://dx.doi.org/10.1055/s-2007-1010815
Preprints | 2021

Ho W-HJ; Law A; Masle-Farquhar E; Castillo L; Mawson A; O’Bryan M; Goodnow C; Ortega DG; Oakes S; Ormandy C, 2021, Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases, , http://dx.doi.org/10.21203/rs.3.rs-842107/v1

Preprints | 2021

Saunus JM; De Luca XM; Northwood K; Raghavendra A; Hasson A; McCart Reed AE; Lim M; Lal S; Vargas AC; Kutasovic JR; Dalley AJ; Miranda M; Kalaw E; Kalita-de Croft P; Gresshoff I; Al-Ejeh F; Gee JMW; Ormandy C; Khanna KK; Beesley J; Chenevix-Trench G; Green AR; Rakha EA; Ellis IO; Nicolau DV; Simpson PT; Lakhani SR, 2021, Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies, , http://dx.doi.org/10.1101/2021.03.30.437624

Preprints | 2020

Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O’Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer, , http://dx.doi.org/10.21203/rs.3.rs-16182/v1

Preprints | 2020

Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O’Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer, , http://dx.doi.org/10.21203/rs.3.rs-16182/v2

Preprints | 2018

Teo WS; Holliday H; Karthikeyan N; Cazet AS; Roden DL; Harvey K; Konrad CV; Murali R; Varghese BA; P. T. A; Chan C-L; McFarland A; Junankar S; Ye S; Yang J; Nikolic I; Shah JS; Baker LA; Millar EKA; Naylor MJ; Ormandy CJ; Lakhani SR; Kaplan W; Mellick AS; O’Toole SA; Swarbrick A; Nair R, 2018, Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1, , http://dx.doi.org/10.1101/497313

Conference Abstracts | 2015

Gallego-Ortega D; Ledger A; Roden D; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Lee B; Kaplan W; Salomon R; Piggin C; Rabinovich B; Millar E; Chtanova T; Swarbrick A; Clark S; Ormandy C, 2015, 'The ETS transcription factor ELF5 drives metastasis via angiogenesis and recruitment of Gr-1+ CD11b+ myeloid derived suppressor cells in luminal breast cancer', in Clinical and Experimental Metastasis, Springer Verlag (Germany), Vol. 32, pp. 203 - 203, presented at MRS 15th International biennial congress of the metastasis research society

Conference Abstracts | 2015

Nair R; Teo WS; Ye S; McFarland A; Harvey K; Roden D; Junankar S; Baker L; Yang J; Fluke N; Millar E; Mellick A; Naylor M; Ormandy C; Lakhani S; O'Toole S; Swarbrick A, 2015, 'The Inhibitor of Differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer', in CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 32, pp. 224 - 224, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900129&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2014

Ortega DG; Ledger A; Roden D; Cho C; Allerdice S; Lee H; Valdes-Mora F; Salomon R; Oakes S; Ormandy C, 2014, 'THE ETS TRANSCRIPTION FACTOR ELF5 IS A KEY DETERMINANT OF THE LETHAL PHENOTYPE IN LUMINAL BREAST CANCER, DRIVING THE ACQUISITION OF ANTIESTROGEN RESISTANCE AND METASTATIC ACTIVITY', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 16 - 17, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2012

Byrne FL; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444

Conference Papers | 2009

O Toole SJ; Swarbrick A; Millar E; McLeod D; Mcneil CM; Qiu MR; Lopez-Knowles E; Caldon E; Oakes SR; Ormandy CJ; Morey AL; Musgrove EA; Henshall SM; Sutherland RL, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development', in Cancer research, American Association Cancer Research, Philadelphia, PA, pp. 70S - 70S

Conference Papers | 2009

O'Toole S; Swarbrick A; Millar E; McLeod D; McNeil C; Qiu M; Lopez-Knowles E; Caldon E; Oakes S; Ormandy C; Morey A; Musgrove E; Henshall S; Sutherland R, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development.', in Cancer Research, American Association for Cancer Research (AACR), pp. 24 - 24, http://dx.doi.org/10.1158/0008-5472.sabcs-24

Conference Papers | 2007

Bhandari M; Kawamoto M; Thomas A; Carati C; Ormandy CJ; Toouli J; Saccone GT, 2007, 'Galanin knockout mice are less susceptible to caerulein-induced acute pancreatitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A250 - A250, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927602142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2007

Williams E; Chaffer C; Oakes SR; Ormandy CJ; Blick T; Thompson E, 2007, 'Mesenchymal to epithetial transition in the establishment of secondary tumours: insights from a bladder carcinoma progression series', in Clinical and Experimental Metastasis, Kluwer Academic Publ, pp. 262 - 262, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000248687200097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers | 2006

Williams ED; Chaffer CL; Oakes SR; Ormandy CJ; Blick T; Thompson EW, 2006, 'Mesenchymal to epithelial transition in the establishment of secondary tumors: Insights from a bladder carcinoma progression series', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606204397&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Reports | 2004

Ormandy CJ, 2004, Discovery of Novel Mammary Developmental and Cancer Genes Using ENU Mutagenesis, Defense Technical Information Center, http://dx.doi.org/10.21236/ada431370, http://dx.doi.org/10.21236/ada431370

Conference Papers | 1997

ClementLacroix P; Ormandy CJ; Lepescheux L; Goffin V; Bouhard B; Amling M; Binart N; GaillardKelly M; Baron R; Kelly PA, 1997, 'Analysis of bone from prolactin receptor knockout mice: Influence of prolactin in normal murine osteoblasts.', in JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. 156 - 156, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XP62700156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preprints |

Valdes-Mora F; Salomon R; Gloss B; Law AMK; Castillo L; Murphy K; Venhuizen J; Magenau A; Papanicolau M; Rodriguez de la Fuente L; Roden DL; Colino-Sanguino Y; Kikhtyak Z; Farbehi N; Conway JRW; Oakes SR; Sikta N; O'Donoghue SI; Cox TR; Timpson P; Ormandy CJ; Gallego Ortega D, Single Cell Transcriptomics Reveals Involution Mimicry During the Specification of the Basal Breast Cancer Subtype, , http://dx.doi.org/10.2139/ssrn.3634808

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Professor Christopher Ormandy