Dr Danijela Kocic

Dr Danijela Kocic

Conjoint Senior Lecturer

PhD, BSc (Hons)

Medicine & Health
School of Clinical Medicine

Dr Danijela Kocic is the Scientific Head of Clinical Pharmacology and Toxicology for SydPath at the St. Vincent’s Hospital in Sydney, Australia. She manages the analysis of Therapeutic Drug Monitoring results to clinicians, patients and other clients requesting rigorous analytical services with a view to optimising patient outcomes in a variety of complex clinical settingsDr Kocic is an active member of TDM Matters Multi-Disciplinary Team Service at St Vincent’s Hospital and recently was appointed as a Conjoint Lecturer at St Vincent’s Clinical School, University of NSW. Dr Kocic is a leading committee member of the NSW Health Pathology Clinical Mass Spectrometry Forum.

Dr Kocic commenced her scientific career with Novartis Pharmaceuticals as a Research Scientist. Following the completion of her PhD, she moved to the Drug Toxicology Unit of the NSW Forensic and Analytical Scientific Service as a Senior Scientist in Charge of  Research & Development and Innovation, continuing to develop high-throughput, robust methods for drug detection and confirmation.

Her research interests are the improvement of the sample throughput of standard LC-MS/MS equipment using Active Flow Technology, TDM and personalised medicine.

+61-2-9823 9190
SydPath - St Vincent’s Pathology - St Vincent’s Hospital Level 6, Xavier Building, 390 Victoria St Darlinghurst NSW 2010
  • Book Chapters | 2015
    2015, 'Recent Advances in Column Technology', in Recent Advances in Column Technology
  • Journal articles | 2023
    2023, 'Effect of Therapeutic Plasma Exchange on Itraconazole Pharmacokinetics: A Case Study', Therapeutic Drug Monitoring, 45, pp. 129 - 132, http://dx.doi.org/10.1097/FTD.0000000000001057
    Journal articles | 2022
    2022, 'Optimal Practice for Vancomycin Therapeutic Drug Monitoring: Position Statement from the Anti-infectives Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology', Therapeutic Drug Monitoring, 44, pp. 121 - 132, http://dx.doi.org/10.1097/FTD.0000000000000944
    Journal articles | 2022
    2022, 'Teaching a New Dog Old Tricks: Ultrafast Liquid Chromatography/Tandem-Mass Spectrometry Analysis of Nine ß-Lactam Antibiotics for Improved Therapeutic Drug Monitoring', Therapeutic Drug Monitoring, 44, pp. 777 - 783, http://dx.doi.org/10.1097/FTD.0000000000001007
    Journal articles | 2021
    2021, 'Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology', British Journal of Clinical Pharmacology, 87, pp. 227 - 236, http://dx.doi.org/10.1111/bcp.14372
    Journal articles | 2020
    2020, 'The management of anti-infective agents in intensive care units: the potential role of a ‘fast’ pharmacology', Expert Review of Clinical Pharmacology, 13, pp. 355 - 366, http://dx.doi.org/10.1080/17512433.2020.1759413
    Journal articles | 2016
    2016, 'Curtain flow column: Optimization of efficiency and sensitivity', Journal of Visualized Experiments, 2016, http://dx.doi.org/10.3791/53471
    Journal articles | 2016
    2016, 'Post column derivatization using reaction flow high performance liquid chromatography columns', Journal of Visualized Experiments, 2016, http://dx.doi.org/10.3791/53462
    Journal articles | 2016
    2016, 'Ultra-fast HPLC MS analyses using active flow technology columns', Microchemical Journal, 127, pp. 160 - 164, http://dx.doi.org/10.1016/j.microc.2016.03.002
    Journal articles | 2015
    2015, 'A new approach to live reaction monitoring using active flow technology in ultra-high-speed HPLC with mass spectral detection', Journal of Mass Spectrometry, 50, pp. 1396 - 1399, http://dx.doi.org/10.1002/jms.3711
    Journal articles | 2015
    2015, 'Improving quantification using curtain flow chromatography columns in the analysis of labile compounds: A study on amino acids', Journal of Chromatography A, 1375, pp. 76 - 81, http://dx.doi.org/10.1016/j.chroma.2014.11.078
    Journal articles | 2015
    2015, 'Multiplexed Detection: Fast Comprehensive Sample Analysis of Tobacco Leaf Extracts Using HPLC with AFT Columns', Journal of Liquid Chromatography and Related Technologies, 38, pp. 1753 - 1758, http://dx.doi.org/10.1080/10826076.2015.1105256
    Journal articles | 2015
    2015, 'Tuning a parallel segmented flow column and enabling multiplexed detection', Journal of Visualized Experiments, 2015, http://dx.doi.org/10.3791/53448
    Journal articles | 2015
    2015, 'Using active flow technology columns for high through-put and efficient analyses: The drive towards ultra-high through-put high-performance liquid chromatography with mass spectral detection', Journal of Chromatography A, 1421, pp. 60 - 67, http://dx.doi.org/10.1016/j.chroma.2015.09.002
    Journal articles | 2014
    2014, 'Using active flow technology columns to achieve near 'direct' injection through-put in HPLC-MS', Microchemical Journal, 118, pp. 193 - 197, http://dx.doi.org/10.1016/j.microc.2014.09.004
    Journal articles | 2013
    2013, 'High through-put and highly sensitive liquid chromatography-tandem mass spectrometry separations of essential amino acids using active flow technology chromatography columns', Journal of Chromatography A, 1305, pp. 102 - 108, http://dx.doi.org/10.1016/j.chroma.2013.07.001

Dean’s Merit List                                                                                                        2008

University of Western Sydney

For Academic Excellence

Dean’s Medal                                                                                                             2009

University of Western Sydney

For Academic Excellence

Employee of the Year                                                                                                 2009

Novartis AH

For GLP Method Development and Validation

Dean’s Merit List                                                                                                        2009

University of Western Sydney

For Academic Excellence

Ellice Swinbourne Prize                                                                                              2009

University of Western Sydney

For the outstanding performance in Chemistry

Honours Scholarship                                                                                                   2009

The University of Western Sydney

Dean’s Merit List                                                                                                        2010

University of Western Sydney

For Academic Excellence

Australian Postgraduate Award                                                                                2012

Department of Industry, Innovation Science, Research and Tertiary


Quarterly Innovation Award                                                                                     2012

Novartis AH

For Non-GLP Method Development and Validation

UWS Innovators Award                                                                                             2014

University of Western Sydney, For demonstrated Innovation Excellence


Emerging Leaders Program                                                                                       2017

NSW Health Pathology, for demonstrated Leadership Skills, 9 months program



Method development and validation for TDM using LC-MS/MS.

Using of novel chromatography columns to achieve ultra-high performance assays. 

Lead committee member  for NSW Health Pathology Clinical Mass Spectrometry Forum

My Research Supervision

ILP Student - Therapeutic Drug Monitoring of Tuberculosis Drugs