Dr David Zahra

Conjoint Senior Lecturer
Medicine & Health
School of Clinical Medicine
  • Journal articles | 2023
    Nguyen T; Lau A; Bier J; Cooke KC; Lenthall H; Ruiz-Diaz S; Avery DT; Brigden H; Zahra D; Sewell WA; Droney L; Okada S; Asano T; Abolhassani H; Chavoshzadeh Z; Abraham RS; Rajapakse N; Klee EW; Church JA; Williams A; Wong M; Burkhart C; Uzel G; Croucher DR; James DE; Ma CS; Brink R; Tangye SG; Deenick EK, 2023, 'Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2', The Journal of experimental medicine, 220, http://dx.doi.org/10.1084/jem.20221020
    Journal articles | 2022
    Bartonicek N; Rouet R; Warren J; Loetsch C; Rodriguez GS; Walters S; Lin F; Zahra D; Blackburn J; Hammond JM; Reis ALM; Deveson IW; Zammit N; Zeraati M; Grey S; Christ D; Mattick JS; Chtanova T; Brink R; Dinger ME; Weatheritt RJ; Sprent J; King C, 2022, 'The retroelement Lx9 puts a brake on the immune response to virus infection', Nature, 608, pp. 757 - 765, http://dx.doi.org/10.1038/s41586-022-05054-9
    Journal articles | 2022
    Ebadi M; Armstrong RT; Mostaghimi P; Wang YD; Alqahtani N; Amirian T; James LA; Parmar A; Zahra D; Hamze H; Koroteev D, 2022, 'Predictive Soft Computing Methods for Building Digital Rock Models Verified by Positron Emission Tomography Experiments', Water Resources Research, 58, http://dx.doi.org/10.1029/2021WR031814
    Journal articles | 2022
    Munoz MA; Skinner OP; Masle-Farquhar E; Jurczyluk J; Xiao Y; Fletcher EK; Kristianto E; Hodson MP; O’Donoghue SI; Kaur S; Brink R; Zahra DG; Deenick EK; Perry KA; Robertson AAB; Mehr S; Hissaria P; Mulders-Manders CM; Simon A; Rogers MJ, 2022, 'Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency', Journal of Clinical Investigation, 132, http://dx.doi.org/10.1172/JCI160929
    Journal articles | 2021
    Sundling C; Lau AWY; Bourne K; Young C; Laurianto C; Hermes JR; Menzies RJ; Butt D; Kräutler NJ; Zahra D; Suan D; Brink R, 2021, 'Positive selection of IgG+ over IgM+ B cells in the germinal center reaction', Immunity, 54, pp. 988 - 1001.e5, http://dx.doi.org/10.1016/j.immuni.2021.03.013
    Journal articles | 2020
    Banati RB; Wilcox P; Xu R; Yin G; Si E; Son ET; Shimizu M; Holsinger RMD; Parmar A; Zahra D; Arthur A; Middleton RJ; Liu GJ; Charil A; Graeber MB, 2020, 'Author Correction: Selective, high-contrast detection of syngeneic glioblastoma in vivo (Scientific Reports, (2020), 10, 1, (9968), 10.1038/s41598-020-67036-z)', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-72364-1
    Journal articles | 2020
    Banati RB; Wilcox P; Xu R; Yin G; Si E; Son ET; Shimizu M; Holsinger RMD; Parmar A; Zahra D; Arthur A; Middleton RJ; Liu GJ; Charil A; Graeber MB, 2020, 'Selective, high-contrast detection of syngeneic glioblastoma in vivo', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-67036-z
    Journal articles | 2020
    Stilwell JD; Buckeridge JSJS; Bevitt JJ; Zahra D, 2020, 'Fossil barnacles from the Antarctic Peninsula: Refining ways of exploring the nature of rare and/or delicate specimens employing X-ray Computer Tomography (CT)', Journal of Paleontology, 94, pp. 1076 - 1081, http://dx.doi.org/10.1017/jpa.2020.33
    Journal articles | 2019
    Moran I; Avery DT; Payne K; Lenthall H; Davies EG; Burns S; Ip W; Oleastro MM; Reisli I; Guner S; Keles S; Notarangelo L; Deenick EK; Goodnow CC; Zahra D; Brink R; Wong M; Tangye SG; Ma CS; Phan TG, 2019, 'B cell–intrinsic requirement for STK4 in humoral immunity in mice and human subjects', Journal of Allergy and Clinical Immunology, 143, pp. 2302 - 2305, http://dx.doi.org/10.1016/j.jaci.2019.02.010
    Journal articles | 2019
    Zammit NW; Siggs OM; Gray PE; Horikawa K; Langley DB; Walters SN; Daley SR; Loetsch C; Warren J; Yap JY; Cultrone D; Russell A; Malle EK; Villanueva JE; Cowley MJ; Gayevskiy V; Dinger ME; Brink R; Zahra D; Chaudhri G; Karupiah G; Whittle B; Roots C; Bertram E; Yamada M; Jeelall Y; Enders A; Clifton BE; Mabbitt PD; Jackson CJ; Watson SR; Jenne CN; Lanier LL; Wiltshire T; Spitzer MH; Nolan GP; Schmitz F; Aderem A; Porebski BT; Buckle AM; Abbott DW; Ziegler JB; Craig ME; Benitez-Aguirre P; Teo J; Tangye SG; King C; Wong M; Cox MP; Phung W; Tang J; Sandoval W; Wertz IE; Christ D; Goodnow CC; Grey ST, 2019, 'Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity', Nature Immunology, 20, pp. 1299 - 1310, http://dx.doi.org/10.1038/s41590-019-0492-0
    Journal articles | 2018
    Avery DT; Kane A; Nguyen T; Lau A; Nguyen A; Lenthall H; Payne K; Shi W; Brigden H; French E; Bier J; Hermes JR; Zahra D; Sewell WA; Butt D; Elliott M; Boztug K; Meyts I; Choo S; Hsu P; Wong M; Berglund LJ; Gray P; O’Sullivan M; Cole T; Holland SM; Ma CS; Burkhart C; Corcoran LM; Phan TG; Brink R; Uzel G; Deenick EK; Tangye SG, 2018, 'Germline-activating mutations in PIK3CD compromise B cell development and function', Journal of Experimental Medicine, 215, pp. 2073 - 2095, http://dx.doi.org/10.1084/jem.20180010
    Journal articles | 2018
    Raoult V; Howell N; Zahra D; Peddemors VM; Howard DL; de Jonge MD; Buchan BL; Williamson JE, 2018, 'Localized zinc distribution in shark vertebrae suggests differential deposition during ontogeny and across vertebral structures', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0190927
    Journal articles | 2018
    Woodward CA; Slee A; Gadd P; Zawadzki A; Hamze H; Parmar A; Zahra D, 2018, 'The role of earthquakes and climate in the formation of diamictic sediments in a New Zealand mountain lake', Quaternary International, 470, pp. 130 - 147, http://dx.doi.org/10.1016/j.quaint.2017.10.051
    Journal articles | 2016
    Raoult V; Peddemors VM; Zahra D; Howell N; Howard DL; De Jonge MD; Williamson JE, 2016, 'Strontium mineralization of shark vertebrae', Scientific Reports, 6, http://dx.doi.org/10.1038/srep29698
    Journal articles | 2016
    Reilhac A; Boisson F; Wimberley C; Parmar A; Zahra D; Hamze H; Davis E; Arthur A; Bouillot C; Charil A; Grégoire MC, 2016, 'Simultaneous scanning of two mice in a small-animal PET scanner: A simulation-based assessment of the signal degradation', Physics in Medicine and Biology, 61, pp. 1371 - 1388, http://dx.doi.org/10.1088/0031-9155/61/3/1371
    Journal articles | 2015
    Callaghan PD; Wimberley CA; Rahardjo GL; Berghofer PJ; Pham TQ; Jackson T; Zahra D; Bourdier T; Wyatt N; Greguric I; Howell NR; Siegele R; Pastuovic Z; Mattner F; Loc’h C; Gregoire MC; Katsifis A, 2015, 'Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [18F]PBR102 and [18F]PBR111 in a model of excitotoxin-induced neuroinflammation', European Journal of Nuclear Medicine and Molecular Imaging, 42, pp. 138 - 151, http://dx.doi.org/10.1007/s00259-014-2895-3
    Journal articles | 2013
    Boisson F; Wimberley CJ; Lehnert W; Zahra D; Pham T; Perkins G; Hamze H; Gregoire MC; Reilhac A, 2013, 'NEMA NU 4-2008 validation and applications of the PET-SORTEO Monte Carlo simulations platform for the geometry of the Inveon PET preclinical scanner', Physics in Medicine and Biology, 58, pp. 6749 - 6763, http://dx.doi.org/10.1088/0031-9155/58/19/6749
    Journal articles | 2013
    Boisson F; Zahra D; Parmar A; Gregoire MC; Meikle SR; Hamse H; Reilhac A, 2013, 'Imaging capabilities of the inveon SPECT system using single-and multipinhole collimators', Journal of Nuclear Medicine, 54, pp. 1833 - 1840, http://dx.doi.org/10.2967/jnumed.112.117572
    Journal articles | 2013
    Mattner F; Staykova M; Berghofer P; Wong HJ; Fordham S; Callaghan P; Jackson T; Pham T; Gregoire MC; Zahra D; Rahardjo G; Linares D; Katsifis A, 2013, 'Central nervous system expression and PET imaging of the translocator protein in relapsing-remitting experimental autoimmune encephalomyelitis', Journal of Nuclear Medicine, 54, pp. 291 - 298, http://dx.doi.org/10.2967/jnumed.112.108894
    Journal articles | 2013
    Verdurand M; Nguyen V; Stark D; Zahra D; Gregoire MC; Zavitsanou K, 2013, 'Comparison of Cannabinoid CB1 Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [18F]MK-9470', International Journal of Molecular Imaging, 2011, pp. 548123, http://dx.doi.org/10.1155/2011/548123
    Journal articles | 2010
    Bamberg CE; MacKay CR; Lee H; Zahra DG; Jackson J; Lim YS; Whitfeld P; Craig S; Corsini E; Lu B; Gerard C; Gerard N, 2010, 'The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction', The Journal of Biological Chemistry, 285, pp. 7633 - 7634, http://dx.doi.org/10.1074/jbc.M109.092106
    Journal articles | 2010
    Xiao D; Zahra D; Bourgeat P; Berghofer P; Tamayo OA; Wimberley C; Gregoire MC; Salvado O, 2010, 'An improved 3D shape context based non-rigid registration method and its application to small animal skeletons registration', Computerized Medical Imaging and Graphics, 34, pp. 321 - 332, http://dx.doi.org/10.1016/j.compmedimag.2009.12.003
    Journal articles | 2008
    Nossent J; Lester S; Zahra DG; MacKay CR; Rischmueller M, 2008, 'Polymorphism in the 5 ` regulatory region of the B-lymphocyte activating factor gene is associated with the Ro/La autoantibody response and serum BAFF levels in primary Sjogren`s syndrome', Rheumatology, 47, pp. 1311 - 1316
    Journal articles | 2006
    Lee HP; Zahra D; Vogelzang A; Newton R; Thatcher J; Quan A; So T; Zwirner J; Koentgen F; Padkjaer S; Mackay F; Whitfeld P; Mackay C, 2006, 'Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies', Nature Biotechnology, 24, pp. 1279 - 1284, http://dx.doi.org/10.1038/nbt1248
    Journal articles | 2002
    Lehmann T; Murphy C; Zahra DG; Handel ML, 2002, 'Reduction of tumor necrosis factor induced nuclear factor-κB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants', Journal of Rheumatology, 29, pp. 787 - 795
    Journal articles | 1999
    Kolzau T; Hansen RS; Zahra D; Reddel RR; Braithwaite AW, 1999, 'Inhibition of SV40 large T antigen induced apoptosis by small T antigen', Oncogene, 18, pp. 5598 - 5603, http://dx.doi.org/10.1038/sj.onc.1202942
    Journal articles | 1999
    Zahra DG; Vancov A; Dunn JM; Hawkins NJ; Ward RL, 1999, 'Selectable in vivo recombination to increase antibody library size - an improved phage display vector system', Gene, 227, pp. 49 - 54, http://dx.doi.org/10.1016/S0378-1119(98)00593-9
    Journal articles | 1995
    De Silva R; Zahra DG; Duncan EL; Reddel RR, 1995, 'Immortalization of human fibroblasts by liposome-mediated transfer of SV40 early region genes', Methods in Cell Science, 17, pp. 75 - 81, http://dx.doi.org/10.1007/BF00986654
    Journal articles | 1995
    Reedel RR; De Silva R; Duncan EL; Rogan EM; Whitaker NJ; Zahra DG; Ke Y; McMenamin MG; Gerwin BI; Harris CC, 1995, 'Sv40‐induced immortalization and ras‐transformation of human bronchial epithelial cells', International Journal of Cancer, 61, pp. 199 - 205, http://dx.doi.org/10.1002/ijc.2910610210
  • Conference Papers | 2011
    Xiao D; Zahra D; Bourgeat P; Berghofer P; Acosta Tamayo O; Wimberley C; Gregoire MC; Salvado O, 2011, 'An accurate 3D shape context based non-rigid registration method for mouse whole-body skeleton registration', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, http://dx.doi.org/10.1117/12.877915
    Conference Papers | 2011
    Xiao D; Zahra D; Bourgeat P; Berghofer P; Tamayo OA; Green H; Gregoire MC; Salvado O, 2011, 'Mouse whole-body organ mapping by non-rigid registration approach', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, http://dx.doi.org/10.1117/12.877921
    Conference Papers | 2010
    Xiao D; Zahra D; Bourgeat P; Berghofer P; Acosta Tamayo O; Wimberley C; Gregoire MC; Salvado O, 2010, 'A non-rigid registration method for mouse whole body skeleton registration', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, http://dx.doi.org/10.1117/12.844067
    Conference Papers | 2010
    Xiao D; Zahra D; Bourgeat P; Berghofer P; Acosta Tamayo O; Wimberley C; Gregoire MC; Salvado O, 2010, 'An improved 3D shape context registration method for non-rigid surface registration', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, http://dx.doi.org/10.1117/12.844058
    Conference Abstracts | 2005
    McGuire H; King CK; Liuwantara D; Zahra DG; Grey S, 2005, 'Promoter polymorphisms in the NOD IL-21 gone', in Tissue Antigens, Blackwell Munksgaard, Melbourne, AUSTRALIA, Vol. 66, pp. 491 - 491, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, AUSTRALIA, 29 November 2005 - 02 December 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700406&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 1997
    Zahra DG; Hawkins NJ; Vancov A; Ward RL, 1997, 'An in vivo recombination strategy using 1oxP-cre to generate large phage display antiBody repertoires', in 9th Lorne Cancer Conference, 9th Lorne Cancer Conference, Lorne, Victoria, pp. E3 - E3, presented at 9th Lorne Cancer Conference, Lorne, Victoria, 13 February 1997 - 16 February 1997