Dr Fan Zhang

B.E., Harbin Institute of Technology, China
M.E., Zhejiang University, China
Ph.D., Nanyang Technological University, Singapore

Medicine & Health
School of Clinical Medicine

I received PhD in Computer Science from Nanyang Technological University Singapore. I am now working as a Postdoctoral Research Fellow at the Microbiome Research Centre, St George and Sutherland Campuses, University of New South Wales in Sydney. My current research focuses on bioinformatics, computational biology, data science and statistical inference.

  • Journal articles | 2022
    Li Y; Zhang F; Zheng H; Kalasabail S; Hicks C; Fung KY; Preaudet A; Putoczki T; Beretov J; Millar EKA; El-Omar E; Jiang XT; Yim HCH, 2022, 'Fecal DNA Virome Is Associated with the Development of Colorectal Neoplasia in a Murine Model of Colorectal Cancer', Pathogens, vol. 11, http://dx.doi.org/10.3390/pathogens11040457
    Journal articles | 2022
    Zhang F; Gia A; Chen G; Gong L; Behary J; Hold GL; Zekry A; Tang X; Sun Y; El-Omar E; Jiang XT, 2022, 'Critical Assessment of Whole Genome and Viral Enrichment Shotgun Metagenome on the Characterization of Stool Total Virome in Hepatocellular Carcinoma Patients', Viruses, vol. 15, pp. 53 - 53, http://dx.doi.org/10.3390/v15010053
    Journal articles | 2021
    Liang ZG; Zhang F; Li Y; Li L; Qu S; Su F; Yu BB; Guan Y; Han L; Li KG; Zhu XD, 2021, 'The Integration of the Pre-Treatment Neutrophil-to-Lymphocyte Ratio in the Eighth Edition of the AJCC Staging System for Nasopharynx Cancer', Frontiers in Oncology, vol. 11, http://dx.doi.org/10.3389/fonc.2021.724467
    Journal articles | 2020
    Liang ZG; Zhang F; Yu BB; Li L; Qu S; Li Y; Guan Y; Liang RB; Han L; Zhu XD, 2020, 'The double-edge role of the addition of adjuvant chemotherapy to concurrent chemoradiotherapy in the treatment of nasopharyngeal carcinoma', Cancer Management and Research, vol. 12, pp. 801 - 812, http://dx.doi.org/10.2147/CMAR.S236128
    Journal articles | 2019
    Liang ZG; Tan HQ; Zhang F; Tan LKR; Lin L; Lenkowicz J; Wang H; Ong EHW; Kusumawidjaja G; Phua JH; Gan SA; Sin SY; Ng YY; Tan TWK; Soong YL; Fong KW; Park SY; Soo KC; Wee JTS; Zhu XD; Valentini V; Boldrini L; Sun Y; Chua MLK, 2019, 'Comparison of radiomics tools for image analyses and clinical prediction in nasopharyngeal carcinoma', British Journal of Radiology, vol. 92, pp. 20190271, http://dx.doi.org/10.1259/bjr.20190271
    Journal articles | 2019
    Lorenzini PA; Chew RSE; Tan CW; Yong JY; Zhang F; Zheng J; Roca X, 2019, 'Human PRPF40B regulates hundreds of alternative splicing targets and represses a hypoxia expression signature', RNA, vol. 25, pp. 905 - 920, http://dx.doi.org/10.1261/rna.069534.118
    Journal articles | 2018
    Liu H; Lorenzini PA; Zhang F; Xu S; Wong MSM; Zheng J; Roca X, 2018, 'Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator', Nucleic Acids Research, vol. 46, pp. 6069 - 6086, http://dx.doi.org/10.1093/nar/gky401
    Journal articles | 2018
    Shanmugam R; Zhang F; Srinivasan H; Richard JLC; Liu KI; Zhang X; Woo CWA; Chua ZHM; Buschdorf JP; Meaney MJ; Tan MH, 2018, 'SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates', Nucleic Acids Research, vol. 46, pp. 7379 - 7395, http://dx.doi.org/10.1093/nar/gky615
    Journal articles | 2018
    Wang Y; Liu KI; Sutrisnoh NAB; Srinivasan H; Zhang J; Li J; Zhang F; Lalith CRJ; Xing H; Shanmugam R; Foo JN; Yeo HT; Ooi KH; Bleckwehl T; Par YYR; Lee SM; Ismail NNB; Sanwari NAB; Lee STV; Lew J; Tan MH, 2018, 'Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells', Genome Biology, vol. 19, http://dx.doi.org/10.1186/s13059-018-1445-x
    Journal articles | 2017
    Pek M; Yatim SMJM; Chen Y; Li J; Gong M; Jiang X; Zhang F; Zheng J; Wu X; Yu Q, 2017, 'Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer', Oncogene, vol. 36, pp. 4975 - 4986, http://dx.doi.org/10.1038/onc.2017.120
    Journal articles | 2016
    Jiang L; Wu WF; Sun LY; Chen PP; Wang W; Benito-Vicente A; Zhang F; Pan XD; Cui W; Yang SW; Zhou YJ; Martin C; Wang LY, 2016, 'The use of targeted exome sequencing in genetic diagnosis of young patients with severe hypercholesterolemia', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep36823
    Journal articles | 2016
    Liu H; Zhang F; Mishra SK; Zhou S; Zheng J, 2016, 'Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep35652
    Journal articles | 2016
    Zhang F; Chen H; Zhao LN; Liu H; Przytycka TM; Zheng J, 2016, 'Generalized logical model based on network topology to capture the dynamical trends of cellular signaling pathways', BMC Systems Biology, vol. 10, http://dx.doi.org/10.1186/s12918-015-0249-9
    Journal articles | 2016
    Zhang F; Liu R; Zheng J, 2016, 'Sig2GRN: A software tool linking signaling pathway with gene regulatory network for dynamic simulation', BMC Systems Biology, vol. 10, http://dx.doi.org/10.1186/s12918-016-0365-1
    Journal articles | 2016
    Zhang F; Wu M; Kwoh CK; Zheng J, 2016, 'Power-law modeling of cancer cell fates driven by signaling data to reveal drug effects', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0165049
    Journal articles | 2015
    Mishra SK; Bhowmick SS; Chua HE; Zhang F; Zheng J, 2015, 'Computational cell fate modelling for discovery of rewiring in apoptotic network for enhanced cancer drug sensitivity', BMC Systems Biology, vol. 9, http://dx.doi.org/10.1186/1752-0509-9-S1-S4
    Journal articles | 2015
    Zhang F; Wu M; Li XJ; Li XL; Kwoh CK; Zheng J, 2015, 'Predicting essential genes and synthetic lethality via influence propagation in signaling pathways of cancer cell fates', Journal of Bioinformatics and Computational Biology, vol. 13, http://dx.doi.org/10.1142/S0219720015410024
    Journal articles | 2014
    Li XJ; Mishra SK; Wu M; Zhang F; Zheng J, 2014, 'Syn-lethality: An integrative knowledge base of synthetic lethality towards discovery of selective anticancer therapies', BioMed Research International, vol. 2014, http://dx.doi.org/10.1155/2014/196034
    Journal articles | 2014
    Wu M; Li X; Zhang F; Li X; Kwoh CK; Zheng J, 2014, 'In silico prediction of synthetic lethality by meta-analysis of genetic interactions, functions, and pathways in yeast and human cancer', Cancer Informatics, vol. 13, pp. 71 - 80, http://dx.doi.org/10.4137/CIN.S14026
  • Conference Papers | 2022
    Chu D; Zhang F; Zhang W; Lin X; Zhang Y, 2022, 'Hierarchical Core Decomposition in Parallel: From Construction to Subgraph Search', in Proceedings - International Conference on Data Engineering, IEEE, pp. 1138 - 1151, presented at 2022 IEEE 38th International Conference on Data Engineering (ICDE), 09 May 2022 - 12 May 2022, http://dx.doi.org/10.1109/ICDE53745.2022.00090
    Conference Papers | 2022
    Pandey D; Szczesniak M; Maclean J; Yim HCH; Zhang F; Graham P; El-Omar EM; Wu P, 2022, 'Dysbiosis in Head and Neck Cancer: Determining Optimal Sampling Site for Oral Microbiome Collection', in Pathogens, WILEY, pp. 27 - 28, http://dx.doi.org/10.3390/pathogens11121550
    Conference Papers | 2014
    Zhang F; Kwoh CK; Wu M; Zheng J, 2014, 'Data-driven prediction of cancer cell fates with a nonlinear model of signaling pathways', in ACM BCB 2014 - 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, pp. 436 - 444, http://dx.doi.org/10.1145/2649387.2649425
    Conference Papers | 2013
    Wu M; Li X; Zhang F; Li X; Kwoh CK; Zheng J, 2013, 'Meta-analysis of genomic and proteomic features to predict synthetic lethality of yeast and human cancer', in 2013 ACM Conference on Bioinformatics, Computational Biology and Biomedical Informatics, ACM-BCB 2013, pp. 384 - 391, http://dx.doi.org/10.1145/2506583.2506653