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Dr Fei Deng
Research Associate

Dr Fei Deng

Engineering
Grad Sch: Biomedical Eng

Dr Deng is currently a research associate in Graduate School of Biomedical Engineering, UNSW. Dr Deng obtained his Master of Engineering in Chemical Engineering from Korea University of Technology and Education (2016, Republic of Korea). He received his Ph.D. degree (specialising in point-of-care biosensing and Biomedical Engineering, 2021) from The University of New South Wales (UNSW), Sydney, NSW, Australia. He subsequently took up a postdoctoral research fellowship at the Graduate School of Biomedical Engineering (GSBmE), UNSW. Deng’s research interests include point-of-care biosensing device, continuous biosensing device, CRISPR biosensing device and in vivo biosensing device. He is currently a key member of a multi-disciplinary team in GSBmE, leading the development of point-of-care biosensing device and real time continuous biosensing device.

 

Editorial Activities:

  • Associate Editor for Diagnostic and Therapeutic Devices, Frontiers in Medical Technology.
  • Topic Editor – Frontiers in Medical Technology, Diagnostic and Therapeutic Devices, Research Topic “Photonic Biosensors for Biomedical Applications and Environmental Monitoring”.

Leading experience

  • The host of Bio-focus seminar (2022), CNBP Node at Graduate School of Biomedical Engineering. 

 
Phone
0451876009
E-mail
fei.deng@unsw.edu.au
  • Journal articles | 2023
    2023, 'Bi-functional antibody-CRISPR/Cas12a ribonucleoprotein conjugate for improved immunoassay performance', Analytica Chimica Acta, 1259, pp. 341211 - 341211, http://dx.doi.org/10.1016/j.aca.2023.341211
    Journal articles | 2023
    2023, 'Mechanistic Observation of Interactions between Macrophages and Inorganic Particles with Different Densities', Small, 19, pp. e2204781, http://dx.doi.org/10.1002/smll.202204781
    Journal articles | 2022
    Li Y; Deng F; Goldys EM, 2022, 'A simple and versatile CRISPR/Cas12a-based immunosensing platform: Towards attomolar level sensitivity for small protein diagnostics', Talanta, 246, pp. 123469, http://dx.doi.org/10.1016/j.talanta.2022.123469
    Journal articles | 2022
    2022, 'A CRISPR/Cas12a-assisted on-fibre immunosensor for ultrasensitive small protein detection in complex biological samples', Analytica Chimica Acta, 1192, pp. 339351 - 339351, http://dx.doi.org/10.1016/j.aca.2021.339351
    Journal articles | 2022
    2022, 'A fluorescent immunosensor on optical fibre for the multiplex detection of proinflammatory cytokines', Sensing and Bio-Sensing Research, 37, pp. 100501 - 100501, http://dx.doi.org/10.1016/j.sbsr.2022.100501
    Journal articles | 2022
    2022, 'Increasing trans-cleavage catalytic efficiency of Cas12a and Cas13a with chemical enhancers: Application to amplified nucleic acid detection', Sensors and Actuators B: Chemical, 373, pp. 132767 - 132767, http://dx.doi.org/10.1016/j.snb.2022.132767
    Journal articles | 2022
    2022, 'Lipid-polymer nanocarrier platform enables X-ray induced photodynamic therapy against human colorectal cancer cells', Biomedicine and Pharmacotherapy, 155, pp. 113837, http://dx.doi.org/10.1016/j.biopha.2022.113837
    Journal articles | 2021
    2021, 'A versatile CRISPR/Cas12a-based sensitivity amplifier suitable for commercial HRP-based ELISA kits', Sensors and Actuators B: Chemical, 347, pp. 130533 - 130533, http://dx.doi.org/10.1016/j.snb.2021.130533
    Journal articles | 2021
    2021, 'CRISPR/Cas12a-powered immunosensor suitable for ultra-sensitive whole Cryptosporidium oocyst detection from water samples using a plate reader', Water Research, 203, pp. 117553 - 117553, http://dx.doi.org/10.1016/j.watres.2021.117553
    Journal articles | 2020
    2020, 'A Method for in Vivo Quantification of Cytokine IL-1β in the Rat Intrathecal Space', ACS Applied Bio Materials, 3, pp. 539 - 546, http://dx.doi.org/10.1021/acsabm.9b00958
    Journal articles | 2020
    2020, 'In vivo intrathecal IL-1β quantification in rats: Monitoring the molecular signals of neuropathic pain', Brain, Behavior, and Immunity, 88, pp. 442 - 450, http://dx.doi.org/10.1016/j.bbi.2020.04.009
    Journal articles | 2019
    2019, 'IFN-γ-induced signal-on fluorescence aptasensors: From hybridization chain reaction amplification to 3D optical fiber sensing interface towards a deployable device for cytokine sensing', Molecular Systems Design and Engineering, 4, pp. 872 - 881, http://dx.doi.org/10.1039/c9me00047j
    Journal articles | 2019
    2019, 'Molecularly imprinted polymer-based reusable biosensing device on stainless steel for spatially localized detection of cytokine IL-1Β', Sensors and Actuators, B: Chemical, 292, pp. 277 - 283, http://dx.doi.org/10.1016/j.snb.2019.04.142
    Journal articles | 2019
    2019, 'Polymer brush based fluorescent immunosensor for direct monitoring of interleukin-1β in rat blood', Analyst, 144, pp. 5682 - 5690, http://dx.doi.org/10.1039/c9an01300h
    Journal articles | 2018
    2018, 'The properties of rice bran carbon/nitrile-butadiene rubber composites fabricated by latex compounding method', POLYMER COMPOSITES, 39, pp. E687 - E696, http://dx.doi.org/10.1002/pc.24126
    Journal articles | 2017
    2017, 'Cellulose Nanocrystals/Poly(Methyl Methacrylate) Nanocomposite Films: Effect of Preparation Method and Loading on the Optical, Thermal, Mechanical, and Gas Barrier Properties', POLYMER COMPOSITES, 38, pp. E137 - E146, http://dx.doi.org/10.1002/pc.23875
    Journal articles | 2017
    2017, 'Effects of Silane Coupling Agents on Tribological Properties of Bentonite/Nitrile Butadiene Rubber Composites', POLYMER COMPOSITES, 38, pp. 2347 - 2357, http://dx.doi.org/10.1002/pc.23817
    Journal articles | 2017
    2017, 'Fabrication and Characterization of Rice Bran Carbon/Styrene Butadiene Rubber Composites Fabricated by Latex Compounding Method', POLYMER COMPOSITES, 38, pp. 2594 - 2602, http://dx.doi.org/10.1002/pc.23852
    Journal articles | 2017
    2017, 'Synergistic reinforcing effects of molybdenum disulfide and bentonite in rubber based nanocomposites', Journal of Vinyl and Additive Technology, 23, pp. E211 - E215, http://dx.doi.org/10.1002/vnl.21568
    Journal articles | 2016
    2016, 'Graft copolymers of microcrystalline cellulose as reinforcing agent for elastomers based on natural rubber', JOURNAL OF APPLIED POLYMER SCIENCE, 133, http://dx.doi.org/10.1002/app.43087
    Journal articles | 2016
    2016, 'Surface modification of novel rice bran carbon functionalized with (3-Mercaptopropyl) trimethoxysilane and its influence on the properties of styrene-butadiene rubber composites', JOURNAL OF COMPOSITE MATERIALS, 50, pp. 2987 - 2999, http://dx.doi.org/10.1177/0021998315615202
    Journal articles | 2015
    2015, 'Effect of coupling agents and ionic liquid on the properties of rice bran carbon/carboxylated styrene butadiene rubber composites', MACROMOLECULAR RESEARCH, 23, pp. 952 - 959, http://dx.doi.org/10.1007/s13233-015-3127-9
    Journal articles | 2015
    2015, 'Synthesis and characterization of microcrystalline cellulose-graft-poly(methyl methacrylate) copolymers and their application as rubber reinforcements', JOURNAL OF APPLIED POLYMER SCIENCE, 132, http://dx.doi.org/10.1002/APP.42666
  • Preprints | 2023
    2023, Bifunctional circular DNA amplifier transforms a classic CRISPR/Cas sensor into an ultrasensitive autocatalytic sensor, , http://dx.doi.org/10.21203/rs.3.rs-2626952/v1

  • Diversity in Engineering Academic Visitors Funding from UNSW ($5K) in 2022, sole-CI. 
  • 3Rs Grant from UNSW ($50K) in 2022, co-CI.
  • MERCK competitive research award (Euro 450,000) in 2022-2024, co-CI.
  • Two Innovation connections grants ($50K each) in 2021 (RG211246, RG210091), which is on ultrasensitive detection of cryptosporidium using CRISPR/Cas technology, co-CI on both.
  • One EDI and ECAN seed funding from UNSW ($1k) in 2021, sole-CI.

  1. UNSW Engineering ECA Awards – Innovation and Engagement Award (2022)
  2. ARC Centre for Nanoscale BioPhotonics (CNBP) Travel Award (2022)
  3. Australian Centre for NanoMedicine (ACN) Travel Award (2022)
  4. PhD Scholarship in Sandwich assay based deployable biosensors (2017-2021)
  5. Excellent Graduate Thesis (Master, 2016)
  6. Foreigners Scholarship (Master, 2013-2016)
  7. Secondary Prize of Tianjin chemistry competition (Bachelor, 2011)

Patent

  1. CRISPR/Cas-associated detection assays, methods and kits. (2021) PCT Patent. International application No. PCT/AU2022/050829.  
  2. Biosensor. (2022) Australian provisional patent No. P0046904AU
  3. Ultrasensitive CRISPR biosensors assisted by circular mediators. (2022) Australian provisional patent No. P0048952AU

 

My Research Supervision

Supervision Experience

  1. Co-supervised PhD research project: Capture and detection of waterborne parasites using existing and emergent technologies (T. Hall)
  2. Co-supervised PhD research project: Programmable nucleases and applications in biosensing (X. Zhai)
  3. Co-supervised PhD research project: Novel biosensors for exosome detection (P. Mohammadnejad)