Dr Felix Aplin

Dr Felix Aplin

Postdoctoral Fellow

- Doctor of Philosophy: School of Medicine, Dentistry & Health Sciences, University of Melbourne.

- Bachelor of Science with Honours (Neuroscience), Australian National University.


Medicine & Health
School of Biomedical Sciences

Felix Aplin is a postdoctoral fellow at the Translational Neuroscience Facility, Faculty of Medicine & Health at UNSW Sydney. He holds a PhD in Medical Sciences from the University of Melbourne, and has completed research fellowships at Johns Hopkins Hospital and Hannover Medical School. He is currently a chief investigator at UNSW exploring new treatments for chronic pain, and he also works in neural engineering, medical bionics, brain-machine interfaces, and neural degeneration. He is particularly interested in using technology to connect with, and repair, our nervous systems. 

  • Books | 2021
    Kral A; Aplin F; Maier H, 2021, Prostheses for the Brain: Introduction to Neuroprosthetics, http://dx.doi.org/10.1016/B978-0-12-818892-7.09991-0
  • Book Chapters | 2023
    Aplin FP; Fridman GY, 2023, 'Implantable Direct Current Neural Modulation', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 787 - 823, http://dx.doi.org/10.1007/978-981-16-5540-1_14
    Book Chapters | 2022
    Aplin FP; Fridman GY, 2022, 'Implantable Direct Current Neural Modulation', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 1 - 37, http://dx.doi.org/10.1007/978-981-15-2848-4_14-1
  • Journal articles | 2024
    Su TF; Hamilton JD; Guo Y; Potas JR; Shivdasani MN; Moalem-Taylor G; Fridman GY; Aplin FP, 2024, 'Peripheral direct current reduces naturally evoked nociceptive activity at the spinal cord in rodent models of pain.', J Neural Eng, 21, http://dx.doi.org/10.1088/1741-2552/ad3b6c
    Journal articles | 2021
    Thakur R; Aplin FP; Fridman GY, 2021, 'A hydrogel-based microfluidic nerve cuff for neuromodulation of peripheral nerves', Micromachines, 12, http://dx.doi.org/10.3390/mi12121522
    Journal articles | 2019
    Aplin FP; Fridman GY, 2019, 'Implantable direct current neural modulation: Theory, feasibility, and efficacy', Frontiers in Neuroscience, 13, http://dx.doi.org/10.3389/fnins.2019.00379
    Journal articles | 2019
    Aplin FP; Singh D; Della Santina CC; Fridman GY, 2019, 'Combined ionic direct current and pulse frequency modulation improves the dynamic range of vestibular canal stimulation', Journal of Vestibular Research: Equilibrium and Orientation, 29, pp. 89 - 96, http://dx.doi.org/10.3233/VES-190651
    Journal articles | 2019
    Aplin FP; Singh D; Santina CCD; Fridman GY, 2019, 'Ionic Direct Current Modulation for Combined Inhibition/Excitation of the Vestibular System', IEEE Transactions on Biomedical Engineering, 66, pp. 775 - 783, http://dx.doi.org/10.1109/TBME.2018.2856698
    Journal articles | 2019
    Manca M; Glowatzki E; Roberts DC; Fridman GY; Aplin FP, 2019, 'Ionic direct current modulation evokes spike-rate adaptation in the vestibular periphery', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-55045-6
    Journal articles | 2018
    Yang F; Anderson M; He S; Stephens K; Zheng Y; Chen Z; Raja SN; Aplin F; Guan Y; Fridman G, 2018, 'Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current', Science Advances, 4, http://dx.doi.org/10.1126/sciadv.aaq1438
    Journal articles | 2016
    Aplin FP; Fletcher EL; Luu CD; Vessey KA; Allen PJ; Guymer RH; Shepherd RK; Shivdasani MN, 2016, 'Stimulation of a suprachoroidal retinal prosthesis drives cortical responses in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 57, pp. 5216 - 5229, http://dx.doi.org/10.1167/iovs.16-19926
    Journal articles | 2016
    Aplin FP; Vessey KA; Luu CD; Guymer RH; Shepherd RK; Fletcher EL, 2016, 'Retinal changes in an ATP-induced model of retinal degeneration', Frontiers in Neuroanatomy, 10, http://dx.doi.org/10.3389/fnana.2016.00046
    Journal articles | 2016
    Ho T; Aplin FP; Jobling AI; Phipps JA; De Iongh RU; Greferath U; Vessey KA; Fletcher EL, 2016, 'Localization and Possible Function of P2X Receptors in Normal and Diseased Retinae', Journal of Ocular Pharmacology and Therapeutics, 32, pp. 509 - 517, http://dx.doi.org/10.1089/jop.2015.0158
    Journal articles | 2014
    Aplin FP; Luu CD; Vessey KA; Guymer RH; Shepherd RK; Fletcher EL, 2014, 'ATP-induced photoreceptor death in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 55, pp. 8319 - 8329, http://dx.doi.org/10.1167/iovs.14-15732
    Journal articles | 2014
    Vessey KA; Greferath U; Aplin FP; Jobling AI; Phipps JA; Ho T; De Iongh RU; Fletcher EL, 2014, 'Adenosine triphosphate-induced photoreceptor death and retinal remodeling in rats', Journal of Comparative Neurology, 522, pp. 2928 - 2950, http://dx.doi.org/10.1002/cne.23558
  • Preprints | 2023
    Su T; Hamilton J; Guo Y; Potas J; Shivdasani M; Moalem-Taylor G; Fridman G; Aplin F, 2023, Peripheral direct current suppresses physiologically evoked nociceptive responses at the spinal cord in rodent models of pain, , http://dx.doi.org/10.1101/2023.06.07.544048
    Conference Papers | 2020
    Cheng C; Aplin FP; Fridman GY, 2020, 'A microfluidic system integrated with shape memory alloy valves for a safe direct current delivery system', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3544 - 3548, http://dx.doi.org/10.1109/EMBC44109.2020.9176474

Grant #GNT1187416: A novel approach for peripheral neuromodulation: Using ionic direct current to treat chronic pain
• Funding Organisation: National Health and Medical Research Council
• Role on Project: Chief Investigator B
• Grant Award Period: June 2020 - January 2023



Festival of Dangerous Ideas 2022 Invited Speaker presented 17-18th of September at the Sydney Carriageworks to a live (200+) audience, as part of the “Unthinkable” program (talk titled “Building Better Brains”.

UNSOMNIA 2021 Recipient and Speaker awarded on 13 April 2021. UNSOMNIA is a fully funded media grant that combines continued professional development with the opportunity to present research in a public forum.

Mavis and Ian Rowe Prize for Retinal Diseases research (AU$2,300) awarded on 24 March 2013 for research on retinal prosthesis function in degenerate retina.

R.B. McComas Research Scholarship (AU$25,000 per annum) awarded between 28 February 2011 and 28 February 2015 during Ph.D. candidature.