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Dr Felix Aplin

Dr Felix Aplin

Lecturer

- Doctor of Philosophy: School of Medicine, Dentistry & Health Sciences, University of Melbourne.

- Bachelor of Science with Honours (Neuroscience), Australian National University.

 

Medicine & Health
School of Biomedical Sciences

Felix Aplin is a postdoctoral fellow at the Translational Neuroscience Facility, Faculty of Medicine & Health at UNSW Sydney. He holds a PhD in Medical Sciences from the University of Melbourne, and has completed research fellowships at Johns Hopkins Hospital and Hannover Medical School. He is currently a chief investigator at UNSW exploring new treatments for chronic pain, and he also works in neural engineering, medical bionics, brain-machine interfaces, and neural degeneration. He is particularly interested in using technology to connect with, and repair, our nervous systems. 
Phone
0402286711
E-mail
f.aplin@unsw.edu.au
  • Books | 2021
    Kral A; Aplin F; Maier H, 2021, Prostheses for the Brain: Introduction to Neuroprosthetics, http://dx.doi.org/10.1016/B978-0-12-818892-7.09991-0
  • Book Chapters | 2023
    Aplin FP; Fridman GY, 2023, 'Implantable Direct Current Neural Modulation', in Thakor NV (ed.), HANDBOOK OF NEUROENGINEERING, SPRINGER-VERLAG SINGAPORE PTE LTD, pp. 787 - 823, http://dx.doi.org/10.1007/978-981-16-5540-1_14
    Book Chapters | 2022
    Aplin FP; Fridman GY, 2022, 'Implantable Direct Current Neural Modulation', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 1 - 37, http://dx.doi.org/10.1007/978-981-15-2848-4_14-1
  • Journal articles | 2025
    Han J; Qin P; Zhu G; Wang R; Bai S; Wen J; Italiano M; Aplin F; Lovell NH; Tsai D; Wang H; Guo T, 2025, 'Modeling the interplay between myelin architecture and local electromagnetic fields', Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2025, pp. 1 - 4, http://dx.doi.org/10.1109/EMBC58623.2025.11253436
    Journal articles | 2024
    Luu BL; Trinh T; Finn HT; Aplin FP; Gandevia SC; Héroux ME; Butler JE, 2024, 'Pain tolerance and the thresholds of human sensory and motor axons to single and repetitive bursts of kilohertz-frequency stimulation', Journal of Physiology, 602, pp. 6281 - 6299, http://dx.doi.org/10.1113/JP286976
    Journal articles | 2024
    Su TF; Hamilton JD; Guo Y; Potas JR; Shivdasani MN; Moalem-Taylor G; Fridman GY; Aplin FP, 2024, 'Peripheral direct current reduces naturally evoked nociceptive activity at the spinal cord in rodent models of pain', Journal of Neural Engineering, 21, http://dx.doi.org/10.1088/1741-2552/ad3b6c
    Journal articles | 2021
    Thakur R; Aplin FP; Fridman GY, 2021, 'A hydrogel-based microfluidic nerve cuff for neuromodulation of peripheral nerves', Micromachines, 12, http://dx.doi.org/10.3390/mi12121522
    Journal articles | 2019
    Aplin FP; Fridman GY, 2019, 'Implantable direct current neural modulation: Theory, feasibility, and efficacy', Frontiers in Neuroscience, 13, http://dx.doi.org/10.3389/fnins.2019.00379
    Journal articles | 2019
    Aplin FP; Singh D; Della Santina CC; Fridman GY, 2019, 'Combined ionic direct current and pulse frequency modulation improves the dynamic range of vestibular canal stimulation', Journal of Vestibular Research Equilibrium and Orientation, 29, pp. 89 - 96, http://dx.doi.org/10.3233/VES-190651
    Journal articles | 2019
    Aplin FP; Singh D; Santina CCD; Fridman GY, 2019, 'Ionic Direct Current Modulation for Combined Inhibition/Excitation of the Vestibular System', IEEE Transactions on Biomedical Engineering, 66, pp. 775 - 783, http://dx.doi.org/10.1109/TBME.2018.2856698
    Journal articles | 2019
    Manca M; Glowatzki E; Roberts DC; Fridman GY; Aplin FP, 2019, 'Ionic direct current modulation evokes spike-rate adaptation in the vestibular periphery', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-55045-6
    Journal articles | 2018
    Yang F; Anderson M; He S; Stephens K; Zheng Y; Chen Z; Raja SN; Aplin F; Guan Y; Fridman G, 2018, 'Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current', Science Advances, 4, http://dx.doi.org/10.1126/sciadv.aaq1438
    Journal articles | 2016
    Aplin FP; Fletcher EL; Luu CD; Vessey KA; Allen PJ; Guymer RH; Shepherd RK; Shivdasani MN, 2016, 'Stimulation of a suprachoroidal retinal prosthesis drives cortical responses in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 57, pp. 5216 - 5229, http://dx.doi.org/10.1167/iovs.16-19926
    Journal articles | 2016
    Aplin FP; Vessey KA; Luu CD; Guymer RH; Shepherd RK; Fletcher EL, 2016, 'Retinal changes in an ATP-induced model of retinal degeneration', Frontiers in Neuroanatomy, 10, http://dx.doi.org/10.3389/fnana.2016.00046
    Journal articles | 2016
    Ho T; Aplin FP; Jobling AI; Phipps JA; De Iongh RU; Greferath U; Vessey KA; Fletcher EL, 2016, 'Localization and Possible Function of P2X Receptors in Normal and Diseased Retinae', Journal of Ocular Pharmacology and Therapeutics, 32, pp. 509 - 517, http://dx.doi.org/10.1089/jop.2015.0158
    Journal articles | 2014
    Aplin FP; Luu CD; Vessey KA; Guymer RH; Shepherd RK; Fletcher EL, 2014, 'ATP-induced photoreceptor death in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 55, pp. 8319 - 8329, http://dx.doi.org/10.1167/iovs.14-15732
    Journal articles | 2014
    Vessey KA; Greferath U; Aplin FP; Jobling AI; Phipps JA; Ho T; De Iongh RU; Fletcher EL, 2014, 'Adenosine triphosphate-induced photoreceptor death and retinal remodeling in rats', Journal of Comparative Neurology, 522, pp. 2928 - 2950, http://dx.doi.org/10.1002/cne.23558
  • Preprints | 2023
    Su T; Hamilton J; Guo Y; Potas J; Shivdasani M; Moalem-Taylor G; Fridman G; Aplin F, 2023, Peripheral direct current suppresses physiologically evoked nociceptive responses at the spinal cord in rodent models of pain, http://dx.doi.org/10.1101/2023.06.07.544048
    Conference Papers | 2020
    Cheng C; Aplin FP; Fridman GY, 2020, 'A microfluidic system integrated with shape memory alloy valves for a safe direct current delivery system', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, pp. 3544 - 3548, http://dx.doi.org/10.1109/EMBC44109.2020.9176474
    Conference Papers | 2012
    Aplin F; Luu C; Shepherd R; Guymer R; Fletcher E, 2012, 'BLIND FELINE MODEL FOR RETINAL PROSTHESIS', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY-BLACKWELL, pp. 104 - 105

Grant #GNT1187416: A novel approach for peripheral neuromodulation: Using ionic direct current to treat chronic pain
• Funding Organisation: National Health and Medical Research Council
• Role on Project: Chief Investigator B
• Grant Award Period: June 2020 - January 2023

 

 

Festival of Dangerous Ideas 2022 Invited Speaker presented 17-18th of September at the Sydney Carriageworks to a live (200+) audience, as part of the “Unthinkable” program (talk titled “Building Better Brains”.

UNSOMNIA 2021 Recipient and Speaker awarded on 13 April 2021. UNSOMNIA is a fully funded media grant that combines continued professional development with the opportunity to present research in a public forum.

Mavis and Ian Rowe Prize for Retinal Diseases research (AU$2,300) awarded on 24 March 2013 for research on retinal prosthesis function in degenerate retina.

R.B. McComas Research Scholarship (AU$25,000 per annum) awarded between 28 February 2011 and 28 February 2015 during Ph.D. candidature.