Mr Ira William Deveson
Conjoint Associate Lecturer

Mr Ira William Deveson

Doctor of Philosophy (biological sciences). Garvan / UNSW (2014-2017).

Bachelor of Philosophy (science), first class honours. Australian National University (2009-12).

medicine-health
St Vincent's Clinical School

Dr Ira Deveson graduated with a Bachelor of Philosophy from the Australian National University in 2012. He completed a PhD at the Garvan Institute from 2014-2017, supervised by Prof John Mattick and Dr Tim Mercer.  Dr Deveson's PhD was focused on genome/transcriptome research and bioinfomatics, and earned him recognition with the JD Catcheside prize from the Genomics Society of Australasia.

Dr Deveson was awarded an Early Career Fellowship from the Cancer Institute NSW (2018) and a prestigious Investigator Grant (EL2) from the NHMRC and Medical Research Futures Fund (2020). After a post-doc stint under Dr Tim Mercer, he was appointed as Head of the Genomic Technologies Group within the Kinghorn Centre for Clinical Genomics in 2020. Under Dr Deveson's leadership, the Genome Technologies Group is testing and developing cutting-edge molecular and computational tools for research and clinical genomics.

Phone
9355 5883
Location
Garvan Institute, 384 Victoria Street, Darlinghurst NSW 2010

Publications

  • Journal articles | 2021
    Mr Ira William Deveson
    Gong B; Li D; Kusko R; Novoradovskaya N; Zhang Y; Wang S; Pabón-Peña C; Zhang Z; Lai K; Cai W; LoCoco JS; Lader E; Richmond TA; Mittal VK; Liu LC; Johann DJ; Willey JC; Bushel PR; Yu Y; Xu C; Chen G; Burgess D; Cawley S; Giorda K; Haseley N; Qiu F; Wilkins K; Arib H; Attwooll C; Babson K; Bao L; Bao W; Lucas AB; Best H; Bhandari A; Bisgin H; Blackburn J; Blomquist TM; Boardman L; Burgher B; Butler DJ; Chang CJ; Chaubey A; Chen T; Chierici M; Chin CR; Close D; Conroy J; Coleman JC; Craig DJ; Crawford E; del Pozo A; Deveson IW; Duncan D; Eterovic AK; Fan X; Foox J; Furlanello C; Ghosal A; Glenn S; Guan M; Haag C; Hang X; Happe S; Hennigan B; Hipp J; Hong H; Horvath K; Hu J; Hung LY; Jarosz M; Kerkhof J; Kipp B; Kreil DP; Łabaj P; Lapunzina P; Li P; Li QZ; Li W; Li Z; Liang Y; Liu S; Liu Z; Ma C; Marella N; Martín-Arenas R; Megherbi DB; Meng Q; Mieczkowski PA; Morrison T; Muzny D; Ning B; Parsons BL; Paweletz CP; Pirooznia M; Qu W; Raymond A; Rindler P; Ringler R; Sadikovic B, 2021, 'Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions', Genome Biology, vol. 22, pp. 109, http://dx.doi.org/10.1186/s13059-021-02315-0
    Journal articles | 2021
    Mr Ira William Deveson
    O'Toole Á; Kraemer MUG; Hill V; Pybus OG; Watts A; Bogoch II; Khan K; Messina JP; Tegally H; Lessells RR; Giandhari J; Pillay S; Tumedi KA; Nyepetsi G; Kebabonye M; Matsheka M; Mine M; Tokajian S; Hassan H; Salloum T; Merhi G; Koweyes J; Geoghegan JL; de Ligt J; Ren X; Storey M; Freed NE; Pattabiraman C; Prasad P; Desai AS; Vasanthapuram R; Schulz TF; Steinbrück L; Stadler T; Parisi A; Bianco A; García de Viedma D; Buenestado-Serrano S; Borges V; Isidro J; Duarte S; Gomes JP; Zuckerman NS; Mandelboim M; Mor O; Seemann T; Arnott A; Draper J; Gall M; Rawlinson W; Deveson I; Schlebusch S; McMahon J; Leong L; Lim CK; Chironna M; Loconsole D; Bal A; Josset L; Holmes E; St. George K; Lasek-Nesselquist E; Sikkema RS; Oude Munnink B; Koopmans M; Brytting M; Sudha rani V; Pavani S; Smura T; Heim A; Kurkela S; Umair M; Salman M; Bartolini B; Rueca M; Drosten C; Wolff T; Silander O; Eggink D; Reusken C; Vennema H; Park A; Carrington C; Sahadeo N; Carr M; Gonzalez G; de Oliveira T; Faria N; Rambaut A, 2021, 'Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2', Wellcome Open Research, vol. 6, pp. 121 - 121, http://dx.doi.org/10.12688/wellcomeopenres.16661.1
    Journal articles | 2021
    Mr Ira William Deveson
    Deveson IW; Gong B; Lai K; LoCoco JS; Richmond TA; Schageman J; Zhang Z; Novoradovskaya N; Willey JC; Jones W; Kusko R; Chen G; Madala BS; Blackburn J; Stevanovski I; Bhandari A; Close D; Conroy J; Hubank M; Marella N; Mieczkowski PA; Qiu F; Sebra R; Stetson D; Sun L; Szankasi P; Tan H; Tang LY; Arib H; Best H; Burgher B; Bushel PR; Casey F; Cawley S; Chang CJ; Choi J; Dinis J; Duncan D; Eterovic AK; Feng L; Ghosal A; Giorda K; Glenn S; Happe S; Haseley N; Horvath K; Hung LY; Jarosz M; Kushwaha G; Li D; Li QZ; Li Z; Liu LC; Liu Z; Ma C; Mason CE; Megherbi DB; Morrison T; Pabón-Peña C; Pirooznia M; Proszek PZ; Raymond A; Rindler P; Ringler R; Scherer A; Shaknovich R; Shi T; Smith M; Song P; Strahl M; Thodima VJ; Tom N; Verma S; Wang J; Wu L; Xiao W; Xu C; Yang M; Zhang G; Zhang S; Zhang Y; Shi L; Tong W; Johann DJ; Mercer TR; Xu J, 2021, 'Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology', Nature Biotechnology, http://dx.doi.org/10.1038/s41587-021-00857-z
    Journal articles | 2021
    Mr Ira William Deveson
    Van Thillo Q; De Bie J; Seneviratne JA; Demeyer S; Omari S; Balachandran A; Zhai V; Tam WL; Sweron B; Geerdens E; Gielen O; Provost S; Segers H; Boeckx N; Marshall GM; Cheung BB; Isobe K; Kato I; Takita J; Amos TG; Deveson IW; McCalmont H; Lock RB; Oxley EP; Garwood MM; Dickins RA; Uyttebroeck A; Carter DR; Cools J; de Bock CE, 2021, 'Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia', Nature Communications, vol. 12, pp. 4164, http://dx.doi.org/10.1038/s41467-021-24442-9
    Journal articles | 2021
    Mr Ira William Deveson
    Kim KW; Deveson IW; Pang CNI; Yeang M; Naing Z; Adikari T; Hammond JM; Stevanovski I; Beukers AG; Verich A; Yin S; McFarlane D; Wilkins MR; Stelzer-Braid S; Bull RA; Craig ME; van Hal SJ; Rawlinson WD, 2021, 'Respiratory viral co-infections among SARS-CoV-2 cases confirmed by virome capture sequencing', Scientific Reports, vol. 11, pp. 3934, http://dx.doi.org/10.1038/s41598-021-83642-x
    Journal articles | 2021
    Mr Ira William Deveson
    Chintalaphani SR; Pineda SS; Deveson IW; Kumar KR, 2021, 'An update on the neurological short tandem repeat expansion disorders and the emergence of long-read sequencing diagnostics', Acta Neuropathologica Communications, vol. 9, pp. 98, http://dx.doi.org/10.1186/s40478-021-01201-x
    Journal articles | 2021
    Mr Ira William Deveson
    Whiteley SL; Holleley CE; Wagner S; Blackburn J; Deveson IW; Marshall Graves JA; Georges A, 2021, 'Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination', PLoS Genetics, vol. 17, pp. e1009465, http://dx.doi.org/10.1371/journal.pgen.1009465
    Journal articles | 2021
    Mr Ira William Deveson
    Madala BS; Reis ALM; Deveson IW; Rawlinson W; Mercer TR, 2021, 'Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests', Scientific Reports, vol. 11, http://dx.doi.org/10.1038/s41598-021-81760-0
    Journal articles | 2020
    Mr Ira William Deveson
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2020, 'Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-15697-9
    Journal articles | 2020
    Mr Ira William Deveson
    Bull RA; Adikari TN; Ferguson JM; Hammond JM; Stevanovski I; Beukers AG; Naing Z; Yeang M; Verich A; Gamaarachchi H; Kim KW; Luciani F; Stelzer-Braid S; Eden JS; Rawlinson WD; van Hal SJ; Deveson IW, 2020, 'Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis', Nature Communications, vol. 11, pp. 6272, http://dx.doi.org/10.1038/s41467-020-20075-6
    Journal articles | 2020
    Mr Ira William Deveson
    Reis ALM; Deveson IW; Wong T; Madala BS; Barker C; Blackburn J; Marcellin E; Mercer TR, 2020, 'A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-17445-5
    Journal articles | 2020
    Mr Ira William Deveson
    Samarakoon H; Punchihewa S; Senanayake A; Hammond JM; Stevanovski I; Ferguson JM; Ragel R; Gamaarachchi H; Deveson IW, 2020, 'Genopo: a nanopore sequencing analysis toolkit for portable Android devices', Communications Biology, vol. 3, http://dx.doi.org/10.1038/s42003-020-01270-z
    Journal articles | 2019
    Mr Ira William Deveson
    Blackburn J; Wong T; Madala BS; Barker C; Hardwick SA; Reis ALM; Deveson IW; Mercer TR, 2019, 'Use of synthetic DNA spike-in controls (sequins) for human genome sequencing', Nature Protocols, vol. 14, pp. 2119 - 2151, http://dx.doi.org/10.1038/s41596-019-0175-1
    Journal articles | 2019
    Mr Ira William Deveson
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2019, 'Diagnosis of fusion genes using targeted RNA sequencing', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-09374-9
    Journal articles | 2019
    Mr Ira William Deveson
    Deveson IW; Madala BS; Blackburn J; Barker C; Wong T; Barton KM; Smith MA; Watkins DN; Mercer TR, 2019, 'Chiral DNA sequences as commutable controls for clinical genomics', Nature Communications, vol. 10, pp. 1342, http://dx.doi.org/10.1038/s41467-019-09272-0
    Journal articles | 2018
    Mr Ira William Deveson
    Deveson IW; Brunck ME; Blackburn J; Tseng E; Hon T; Clark TA; Clark MB; Crawford J; Dinger ME; Nielsen LK; Mattick JS; Mercer TR, 2018, 'Universal Alternative Splicing of Noncoding Exons', Cell Systems, vol. 6, pp. 245 - 255.e5, http://dx.doi.org/10.1016/j.cels.2017.12.005
    Journal articles | 2018
    Mr Ira William Deveson
    Hardwick SA; Chen WY; Wong T; Kanakamedala BS; Deveson IW; Ongley SE; Santini NS; Marcellin E; Smith MA; Nielsen LK; Lovelock CE; Neilan BA; Mercer TR, 2018, 'Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-05555-0
    Journal articles | 2018
    Mr Ira William Deveson
    Deveson I; Madala BS; Blackburn J; Barker C; Wong T; Barton K; Smith M; Watkins N; Mercer T, 2018, 'Chiral DNA sequences as commutable reference standards for clinical genomics', BIORXIV, http://dx.doi.org/10.1101/404285
    Journal articles | 2017
    Mr Ira William Deveson
    Zheng Z; Reichel M; Deveson I; Wong G; Li J; Millar AA, 2017, 'Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy', PLANT PHYSIOLOGY, vol. 174, pp. 1764 - 1778, http://dx.doi.org/10.1104/pp.16.01898
    Journal articles | 2017
    Mr Ira William Deveson
    Hardwick SA; Deveson IW; Mercer TR, 2017, 'Reference standards for next-generation sequencing', Nature Reviews Genetics, vol. 18, pp. 473 - 484, http://dx.doi.org/10.1038/nrg.2017.44
    Journal articles | 2017
    Mr Ira William Deveson
    Wong T; Deveson IW; Hardwick SA; Mercer TR, 2017, 'ANAQUIN: A software toolkit for the analysis of spike-in controls for next generation sequencing', Bioinformatics, vol. 33, pp. 1723 - 1724, http://dx.doi.org/10.1093/bioinformatics/btx038
    Journal articles | 2017
    Mr Ira William Deveson
    Deveson IW; Hardwick SA; Mercer TR; Mattick JS, 2017, 'The Dimensions, Dynamics, and Relevance of the Mammalian Noncoding Transcriptome', Trends in Genetics, vol. 33, pp. 464 - 478, http://dx.doi.org/10.1016/j.tig.2017.04.004
    Journal articles | 2017
    Mr Ira William Deveson
    Deveson IW; Holleley CE; Blackburn J; Marshall Graves JA; Mattick JS; Waters PD; Georges A, 2017, 'Differential intron retention in Jumonji chromatin modifier genes is implicated in reptile temperature-dependent sex determination', Science Advances, vol. 3, http://dx.doi.org/10.1126/sciadv.1700731
    Journal articles | 2016
    Mr Ira William Deveson
    Hardwick SA; Chen WY; Wong T; Deveson IW; Blackburn J; Andersen SB; Nielsen LK; Mattick JS; Mercer TR, 2016, 'Spliced synthetic genes as internal controls in RNA sequencing experiments', Nature Methods, vol. 13, pp. 792 - 798, http://dx.doi.org/10.1038/nmeth.3958
    Journal articles | 2016
    Mr Ira William Deveson
    Deveson IW; Chen WY; Wong T; Hardwick SA; Andersen SB; Nielsen LK; Mattick JS; Mercer TR, 2016, 'Representing genetic variation with synthetic DNA standards', Nature Methods, vol. 13, pp. 784 - 791, http://dx.doi.org/10.1038/nmeth.3957
    Journal articles | 2013
    Mr Ira William Deveson
    Deveson I; Li J; Millar AA, 2013, 'MicroRNAs with analogous target complementarities perform with highly variable efficacies in Arabidopsis', FEBS LETTERS, vol. 587, pp. 3703 - 3708, http://dx.doi.org/10.1016/j.febslet.2013.09.037
    Journal articles | 2013
    Mr Ira William Deveson
    Deveson I; Li J; Millar AA, 2013, 'Expression of human ARGONAUTE 2 inhibits endogenous microRNA activity in Arabidopsis', FRONTIERS IN PLANT SCIENCE, vol. 4, http://dx.doi.org/10.3389/fpls.2013.00096
    Journal articles |
    Mr Ira William Deveson
    Gamaarachchi H; Samarakoon H; Jenner S; Ferguson J; Amos T; Hammond J; Saadat H; Smith M; Parameswaran S; Deveson I, 'SLOW5: a new file format enables massive acceleration of nanopore sequencing data analysis', , http://dx.doi.org/10.21203/rs.3.rs-668517/v1
    Journal articles |
    Mr Ira William Deveson
    Gamaarachchi H; Samarakoon H; Jenner SP; Ferguson JM; Amos TG; Hammond JM; Saadat H; Smith MA; Parameswaran S; Deveson IW, 'SLOW5: a new file format enables massive acceleration of nanopore sequencing data analysis', , http://dx.doi.org/10.1101/2021.06.29.450255
    Journal articles |
    Mr Ira William Deveson
    Ferguson JM; Gamaarachchi H; Nguyen T; Gollon A; Tong S; Aquilina-Reid C; Bowen-James R; Deveson IW, 'InterARTIC: an interactive web application for whole-genome nanopore sequencing analysis of SARS-CoV-2 and other viruses', , http://dx.doi.org/10.1101/2021.04.21.440861
    Journal articles |
    Mr Ira William Deveson
    Whiteley SL; Holleley CE; Wagner S; Blackburn J; Deveson IW; Graves JAM; Georges A, 'Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination', , http://dx.doi.org/10.1101/2021.02.03.429474

Awards

Garvan Rising Star Award (2018).

DG Catcheside Prize, Genetics Society of Australasia (2017).

Stuart Furler Travel Award, Garvan Institute (2016).

Graduate Research Excellence Scholarship, UNSW (2014-2017).

3 Minute Thesis winner, Garvan Institute (2014).

University Medal for Biology, Australian National University (2012).

Grants

MRFF Investigator Grant – Emerging Leadership Level 2 (2020-2025).

Developing synthetic DNA reference standards (sequins) to ensure accuracy in emerging genomic technologies.

Cancer Institute NSW Early Career Fellowship (2018-2020).

Representing the cancer genome with synthetic spike-in controls.

UNSW-USA Networks of Excellence Mobility Grant (2019).

Interrogating the human transcriptome with high-throughput CRIPSR knockout screens.

Media