Dr Jane Ellen Carland
Senior Lecturer

Dr Jane Ellen Carland

BMedSci (HonsI), PhD

Medicine & Health
Pharmacology

Jane Carland is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney. She is also a Senior Lecturer, School of Medical Sciences, UNSW Sydney.

Jane gained her PhD from the University of Sydney, Australia under the supervision of Professors Mary Collins (Chebib) and Graham Johnston. She subsequently took up a post-doctoral position with Professors Jeremy Lambert and John Peters at the University of Dundee, UK and returned to Australia as a UNSW Vice-Chancellors Research Fellow. Jane then worked within the Transporter Biology Group in the Discipline of Pharmacology, University of Sydney with Professor Robert Vandenberg and has since moved to work within the Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney with Professor Ric Day.

Jane’s background in pharmacology extends from molecular pharmacology to quality use of medicines. Jane's research interests include structure-function studies of neurotransmitter receptors and transporters, optimising immunosuppressant therapy in heart and lung transplant, extending use of metformin to complex patient populations (including heart failure and renal failure), influences on prescribing decision-making, evaluating therapeutic drug monitoring processes and exploring informed consent – an ethical tenant that is central to the researcher-participant relationship in clinical research. Jane’s love of research is reflected in her interest in conveying research outcomes to the community, from pre-school science classes to School Outreach programs.

Phone
02 8382 2617
Location
Department of Clinical Pharmacology & Toxicology, Therapeutics Centre, St Vincent’s Hospital Sydney Conjoint Senior Lecturer, St Vincent’s Clinical School, UNSW Sydney Level 2 Xavier Building, 390 Victoria Street, Darlinghurst, Sydney 2010

Publications

  • Book Chapters | 2018
    Dr Jane Ellen Carland
    Baysari M; Chan J; Carland J; Stocker S; Moran M; Day R, 2018, 'Usability of Reports Generated by a Computerised Dose Prediction Software', in Connecting the System to Enhance the Practitioner and Consumer Experience in Healthcare, IOS Press, Netherlands, pp. 27 - 32, http://dx.doi.org/10.3233/978-1-61499-890-7-27
    Book Chapters | 2013
    Dr Jane Ellen Carland
    E. J; R. A; J. A; M. R; J. R, 2013, 'Directed Mutagenesis in Structure Activity Studies of Neurotransmitter Transporters', in Genetic Manipulation of DNA and Protein - Examples from Current Research, InTech, http://dx.doi.org/10.5772/45721
    Book Chapters | 2012
    Dr Jane Ellen Carland
    Peters J; Cooper M; Livesey M; Carland J; Lambert J, 2012, '5-HT3 receptors', in Ion Channels: From Structure to Function, http://dx.doi.org/10.1093/acprof:oso/9780199296750.003.0007
  • Journal articles | 2021
    Dr Jane Ellen Carland
    Uebel K; Iqbal MP; Carland J; Smith G; Islam MS; Shulruf B; Nathan S, 2021, 'Factors Determining Medical Students’ Experience in an Independent Research Year During the Medical Program', Medical Science Educator, http://dx.doi.org/10.1007/s40670-021-01340-9
    Journal articles | 2021
    Dr Jane Ellen Carland
    Uster DW; Stocker SL; Carland JE; Brett J; Marriott DJE; Day RO; Wicha SG, 2021, 'A Model Averaging/Selection Approach Improves the Predictive Performance of Model-Informed Precision Dosing: Vancomycin as a Case Study', Clinical Pharmacology and Therapeutics, vol. 109, pp. 175 - 183, http://dx.doi.org/10.1002/cpt.2065
    Journal articles | 2021
    Dr Jane Ellen Carland
    Stocker SL; Carland JE; Reuter SE; Stacy AE; Schaffer AL; Stefani M; Lau C; Kirubakaran R; Yang JJ; Shen CFJ; Roberts DM; Marriott DJE; Day RO; Brett J, 2021, 'Evaluation of a Pilot Vancomycin Precision Dosing Advisory Service on Target Exposure Attainment Using an Interrupted Time Series Analysis', Clinical Pharmacology and Therapeutics, vol. 109, pp. 212 - 221, http://dx.doi.org/10.1002/cpt.2113
    Journal articles | 2021
    Dr Jane Ellen Carland
    Carland JE; Elhage T; Baysari MT; Stocker SL; Marriott DJE; Taylor N; Day RO, 2021, 'Would they trust it? An exploration of psychosocial and environmental factors affecting prescriber acceptance of computerised dose-recommendation software', British Journal of Clinical Pharmacology, vol. 87, pp. 1215 - 1233, http://dx.doi.org/10.1111/bcp.14496
    Journal articles | 2021
    Dr Jane Ellen Carland
    Cunio CB; Uster DW; Carland JE; Buscher H; Liu Z; Brett J; Stefani M; Jones GRD; Day RO; Wicha SG; Stocker SL, 2021, 'Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients', Clinical Microbiology and Infection, vol. 27, pp. 783.e7 - 783.e14, http://dx.doi.org/10.1016/j.cmi.2020.07.005
    Journal articles | 2021
    Dr Jane Ellen Carland
    Ryan AC; Carland JE; McLeay RC; Lau C; Marriott DJE; Day RO; Stocker SL, 2021, 'Evaluation of amikacin use and comparison of the models implemented in two Bayesian forecasting software packages to guide dosing', British Journal of Clinical Pharmacology, vol. 87, pp. 1422 - 1431, http://dx.doi.org/10.1111/bcp.14542
    Journal articles | 2021
    Dr Jane Ellen Carland
    Carland JE; Stocker SL; Baysari MT; Li C; Själin J; Moran MA; Tang S; Sandaradura I; Elhage T; Gilbey T; Williams KM; Marriott DJE; Day RO, 2021, 'Are vancomycin dosing guidelines followed? A mixed methods study of vancomycin prescribing practices', British Journal of Clinical Pharmacology, http://dx.doi.org/10.1111/bcp.14834
    Journal articles | 2021
    Dr Jane Ellen Carland
    Roydhouse SA; Carland JE; Debono DS; Baysari MT; Reuter SE; Staciwa AJ; Sandhu APK; Day RO; Stocker SL, 2021, 'Accuracy of documented administration times for intravenous antimicrobial drugs and impact on dosing decisions', British Journal of Clinical Pharmacology, http://dx.doi.org/10.1111/bcp.14844
    Journal articles | 2021
    Dr Jane Ellen Carland
    Braithwaite HE; Darley DR; Brett J; Day RO; Carland JE, 2021, 'Identifying the association between tacrolimus exposure and toxicity in heart and lung transplant recipients: A systematic review', Transplantation Reviews, vol. 35, http://dx.doi.org/10.1016/j.trre.2021.100610
    Journal articles | 2021
    Dr Jane Ellen Carland
    Kirubakaran R; Stocker SL; Carlos L; Day RO; Carland JE, 2021, 'Tacrolimus Therapy in Adult Heart Transplant Recipients: Evaluation of a Bayesian Forecasting Software.', Ther Drug Monit, http://dx.doi.org/10.1097/FTD.0000000000000909
    Journal articles | 2021
    Dr Jane Ellen Carland
    Coleshill MJ; Aung E; Carland JE; Faasse K; Stocker S; Day RO, 2021, 'Rebranding Gout: Could a Name Change for Gout Improve Adherence to Urate-Lowering Therapy?', Therapeutic Innovation and Regulatory Science, vol. 55, pp. 138 - 141, http://dx.doi.org/10.1007/s43441-020-00198-0
    Journal articles | 2020
    Dr Jane Ellen Carland
    Xu A; Baysari MT; Stocker SL; Leow LJ; Day RO; Carland JE, 2020, 'Researchers' views on, and experiences with, the requirement to obtain informed consent in research involving human participants: A qualitative study', BMC Medical Ethics, vol. 21, pp. 93, http://dx.doi.org/10.1186/s12910-020-00538-7
    Journal articles | 2020
    Dr Jane Ellen Carland
    Shingde RV; Reuter SE; Graham GG; Carland JE; Williams KM; Day RO; Stocker SL, 2020, 'Assessing the accuracy of two bayesian forecasting programs in estimating vancomycin drug exposure', Journal of Antimicrobial Chemotherapy, vol. 75, pp. 3293 - 3302, http://dx.doi.org/10.1093/jac/dkaa320
    Journal articles | 2020
    Dr Jane Ellen Carland
    Smith FC; Stocker SL; Danta M; Carland JE; Kumar SS; Liu Z; Greenfield JR; Braithwaite HE; Cheng TS; Graham GG; Williams KM; Day RO, 2020, 'The safety and pharmacokinetics of metformin in patients with chronic liver disease', Alimentary Pharmacology and Therapeutics, vol. 51, pp. 565 - 575, http://dx.doi.org/10.1111/apt.15635
    Journal articles | 2020
    Dr Jane Ellen Carland
    Chaudhri K; Stocker SL; Williams KM; McLeay RC; Marriott DJE; Di Tanna GL; Day RO; Carland JE, 2020, 'Voriconazole: An audit of hospital-based dosing and monitoring and evaluation of the predictive performance of a dose-prediction software package', Journal of Antimicrobial Chemotherapy, vol. 75, pp. 1981 - 1984, http://dx.doi.org/10.1093/jac/dkaa098
    Journal articles | 2020
    Dr Jane Ellen Carland
    Kirubakaran R; Stocker SL; Hennig S; Day RO; Carland JE, 2020, 'Population Pharmacokinetic Models of Tacrolimus in Adult Transplant Recipients: A Systematic Review', Clinical Pharmacokinetics, vol. 59, pp. 1357 - 1392, http://dx.doi.org/10.1007/s40262-020-00922-x
    Journal articles | 2020
    Dr Jane Ellen Carland
    Kamel B; Graham GG; Stocker SL; Liu Z; Williams KM; Carland JE; Pile KD; Day RO, 2020, 'A pharmacokinetic-pharmacodynamic study of a single dose of febuxostat in healthy subjects', British Journal of Clinical Pharmacology, vol. 86, pp. 2486 - 2496, http://dx.doi.org/10.1111/bcp.14357
    Journal articles | 2020
    Dr Jane Ellen Carland
    Van Dort BA; Baysari MT; Carland JE; Stocker SL; Braithwaite HE; Fernon AR; Day RO, 2020, 'Education to improve vancomycin use: the perspectives of educators and education recipients', Internal Medicine Journal, vol. 50, pp. 565 - 572, http://dx.doi.org/10.1111/imj.14408
    Journal articles | 2019
    Dr Jane Ellen Carland
    Shingde RV; Graham GG; Reuter SE; Carland JE; Day RO; Stocker SL, 2019, 'Comparison of the Area under the Curve for Vancomycin Estimated Using Compartmental and Noncompartmental Methods in Adult Patients with Normal Renal Function', Therapeutic Drug Monitoring, vol. 41, pp. 726 - 731, http://dx.doi.org/10.1097/FTD.0000000000000690
    Journal articles | 2019
    Dr Jane Ellen Carland
    Abdel Shaheed C; Carland JE; Graham GG; Stocker SL; Smith G; Hicks M; Williams KM; Furlong T; Macdonald P; Greenfield JR; Smith FC; Chowdhury G; Day RO, 2019, 'Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis', British Journal of Clinical Pharmacology, vol. 85, pp. 2772 - 2783, http://dx.doi.org/10.1111/bcp.14107
    Journal articles | 2019
    Dr Jane Ellen Carland
    Broeker A; Nardecchia M; Klinker KP; Derendorf H; Day RO; Marriott DJ; Carland JE; Stocker SL; Wicha SG, 2019, 'Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting', Clinical Microbiology and Infection, vol. 25, pp. 1286.e1 - 1286.e7, http://dx.doi.org/10.1016/j.cmi.2019.02.029
    Journal articles | 2019
    Dr Jane Ellen Carland
    Day RO; Lau W; Stocker SL; Aung E; Coleshill MJ; Schulz M; Bechara J; Carland JE; Graham GG; Williams KM; McLachlan AJ, 2019, 'Management of gout in older people', Journal of Pharmacy Practice and Research, vol. 49, pp. 90 - 97, http://dx.doi.org/10.1002/jppr.1511
    Journal articles | 2019
    Dr Jane Ellen Carland
    Kamel B; Williams KM; Graham GG; Norris RLG; Stocker SL; Carland JE; Pile KD; Day RO, 2019, 'Determination of febuxostat in human plasma by high performance liquid chromatography (HPLC) with fluorescence-detection', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1126-1127, http://dx.doi.org/10.1016/j.jchromb.2019.121764
    Journal articles | 2019
    Dr Jane Ellen Carland
    Shingde RV; Graham GG; Reuter SE; Carland JE; Day RO; Stocker SL, 2019, 'Comparison of the Area Under the Curve for Vancomycin Estimated Using Compartmental and Noncompartmental Methods in Adult Patients With Normal Renal Function.', Ther Drug Monit, vol. 41, pp. 726 - 731, http://dx.doi.org/10.1097/FTD.0000000000000690
    Journal articles | 2018
    Dr Jane Ellen Carland
    Roberts DM; Sevastos J; Carland JE; Stocker SL; Lea-Henry TN, 2018, 'Clinical pharmacokinetics in kidney disease application to rational design of dosing regimens', Clinical Journal of the American Society of Nephrology, vol. 13, pp. 1254 - 1263, http://dx.doi.org/10.2215/CJN.05150418
    Journal articles | 2018
    Dr Jane Ellen Carland
    Lea-Henry TN; Carland JE; Stocker SL; Sevastos J; Roberts DM, 2018, 'Clinical pharmacokinetics in kidney disease: Fundamental principles', Clinical Journal of the American Society of Nephrology, vol. 13, pp. 1085 - 1095, http://dx.doi.org/10.2215/CJN.00340118
    Journal articles | 2018
    Dr Jane Ellen Carland
    Nguyen AD; Frensham LJ; Baysari MT; Carland JE; Day RO, 2018, 'Patients' use of mobile health applications: What general practitioners think', Family Practice, vol. 36, pp. 214 - 218, http://dx.doi.org/10.1093/fampra/cmy052
    Journal articles | 2018
    Dr Jane Ellen Carland
    Carland JE; Thomas M; Mostyn SN; Subramanian N; O'Mara ML; Ryan RM; Vandenberg RJ, 2018, 'Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2', ACS Chemical Neuroscience, vol. 9, pp. 603 - 614, http://dx.doi.org/10.1021/acschemneuro.7b00407
    Journal articles | 2018
    Dr Jane Ellen Carland
    Chan JOS; Baysari MT; Carland JE; Sandaradura I; Moran M; Day RO, 2018, 'Barriers and facilitators of appropriate vancomycin use: prescribing context is key', European Journal of Clinical Pharmacology, vol. 74, pp. 1523 - 1529, http://dx.doi.org/10.1007/s00228-018-2525-2
    Journal articles | 2018
    Dr Jane Ellen Carland
    Day R; Kamel B; Graham GG; Williams KM; Stocker SL; Carland JE; Pile KD; Mcguigan LE; Portek IJ; Mcgill NW, 2018, 'A Multicentre Open-Label Pharmacokinetic-Pharmacodynamic Study of Febuxostat in Patients with Chronic Gout', Proceedings for Annual Meeting of The Japanese Pharmacological Society, vol. WCP2018, http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po1-11-12
    Journal articles | 2018
    Dr Jane Ellen Carland
    Carland JE; Smith FC; Day RO, 2018, 'Lactic Acidosis, Metformin Use, and Dose-Response Association', JAMA Internal Medicine, vol. 178, pp. 1428 - 1429, http://dx.doi.org/10.1001/jamainternmed.2018.4448
    Journal articles | 2017
    Dr Jane Ellen Carland
    Mostyn SN; Carland JE; Shimmon S; Ryan RM; Rawling T; Vandenberg RJ, 2017, 'Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2', ACS Chemical Neuroscience, vol. 8, pp. 1949 - 1959, http://dx.doi.org/10.1021/acschemneuro.7b00105
    Journal articles | 2017
    Dr Jane Ellen Carland
    Day RO; Kannangara DRW; Stocker SL; Carland JE; Williams KM; Graham GG, 2017, 'Allopurinol: insights from studies of dose–response relationships', Expert Opinion on Drug Metabolism and Toxicology, vol. 13, pp. 449 - 462, http://dx.doi.org/10.1080/17425255.2017.1269745
    Journal articles | 2016
    Dr Jane Ellen Carland
    Vandenberg RJ; Mostyn SN; Carland JE; Ryan RM, 2016, 'Glycine transporter2 inhibitors: Getting the balance right', Neurochemistry International, vol. 98, pp. 89 - 93, http://dx.doi.org/10.1016/j.neuint.2015.12.007
    Journal articles | 2016
    Dr Jane Ellen Carland
    Subramanian N; Scopelitti AJ; Carland JE; Ryan RM; O'Mara ML; Vandenberg RJ, 2016, 'Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0157583
    Journal articles | 2016
    Dr Jane Ellen Carland
    Subramanian N; Scopelliti AJ; Carland JE; Ryan RM; O'Mara ML; Vandenberg RJ, 2016, 'Correction: Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0159896
    Journal articles | 2015
    Dr Jane Ellen Carland
    Vandenberg R; Carland J; Edington A; Ryan R, 2015, 'Molecular Basis for Substrate and Inhibitor Interactions with the Glycine Transporter, GlyT2', FASEB JOURNAL, vol. 29, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361470504039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2015
    Dr Jane Ellen Carland
    Carland JE; Yamamoto I; Hanrahan JR; Abdel-Halim H; Lewis TM; Absalom N; Chebib M, 2015, 'A Hydrophobic Area of the GABA ρ1 Receptor Containing Phenylalanine 124 Influences Both Receptor Activation and Deactivation', Journal of Molecular Neuroscience, vol. 55, pp. 305 - 313, http://dx.doi.org/10.1007/s12031-014-0322-7
    Journal articles | 2014
    Dr Jane Ellen Carland
    Vandenberg RJ; Ryan RM; Carland JE; Imlach WL; Christie MJ, 2014, 'Glycine transport inhibitors for the treatment of pain', Trends in Pharmacological Sciences, vol. 35, pp. 423 - 430, http://dx.doi.org/10.1016/j.tips.2014.05.006
    Journal articles | 2014
    Dr Jane Ellen Carland
    Carland JE; Handford CA; Ryan RM; Vandenberg RJ, 2014, 'Lipid inhibitors of high affinity glycine transporters: Identification of a novel class of analgesics', Neurochemistry International, vol. 73, pp. 211 - 216, http://dx.doi.org/10.1016/j.neuint.2013.08.012
    Journal articles | 2013
    Dr Jane Ellen Carland
    Carland JE; Mansfield RE; Ryan RM; Vandenberg RJ, 2013, 'Oleoyl-L-carnitine inhibits glycine transport by GlyT2', British Journal of Pharmacology, vol. 168, pp. 891 - 902, http://dx.doi.org/10.1111/j.1476-5381.2012.02213.x
    Journal articles | 2013
    Dr Jane Ellen Carland
    Carland JE; Cooper MA; Livesey MR; Hales TG; Peters JA; Lambert JJ, 2013, 'Mutagenic analysis of the intracellular portals of the human 5-HT 3A receptor', Journal of Biological Chemistry, vol. 288, pp. 31592 - 31601, http://dx.doi.org/10.1074/jbc.M113.503300
    Journal articles | 2012
    Dr Jane Ellen Carland
    Yamamoto I; Absalom N; Carland JE; Doddareddy MR; Gavande N; Johnston GAR; Hanrahan JR; Chebib M, 2012, 'Differentiating enantioselective actions of GABOB: A possible role for threonine 244 in the binding site of GABAc ρ1 receptors', ACS Chemical Neuroscience, vol. 3, pp. 665 - 673, http://dx.doi.org/10.1021/cn3000229
    Journal articles | 2012
    Dr Jane Ellen Carland
    Yamamoto I; Carland JE; Locock K; Gavande N; Absalom N; Hanrahan JR; Allan RD; Johnston GAR; Chebib M, 2012, 'Structurally diverse GABA antagonists interact differently with open and closed conformational states of the ρ1 receptor', ACS Chemical Neuroscience, vol. 3, pp. 293 - 301, http://dx.doi.org/10.1021/cn200121r
    Journal articles | 2010
    Dr Jane Ellen Carland
    Peters JA; Cooper MA; Carland JE; Livesey MR; Hales TG; Lambert JJ, 2010, 'Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors', Journal of Physiology, vol. 588, pp. 587 - 596, http://dx.doi.org/10.1113/jphysiol.2009.183137
    Journal articles | 2010
    Dr Jane Ellen Carland
    Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ; Barry PH, 2010, 'External divalent cations increase anion-cation permeability ratio in glycine receptor channels', Pflugers Archiv - European Journal of Physiology, vol. 460, pp. 131 - 152, http://dx.doi.org/10.1007/s00424-010-0792-6
    Journal articles | 2009
    Dr Jane Ellen Carland
    Carland JE; cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Peters JA; Lambert J; Moorhouse AJ, 2009, 'Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels', The Journal of Biological Chemistry, vol. 284, pp. 2023 - 2030, http://dx.doi.org/10.1074/jbc.M806618200
    Journal articles | 2008
    Dr Jane Ellen Carland
    Livesey M; Cooper M; Deeb T; Carland JE; kozuska J; Hales T; Lambert J; Peters J, 2008, 'Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor', The Journal of Biological Chemistry, vol. 283, pp. 19301 - 19313, http://dx.doi.org/10.1074/jbc.M802406200
    Journal articles | 2008
    Dr Jane Ellen Carland
    Carland JE; Johnston G; Chebib M, 2008, 'Relative impact of residues at the intracellular and extracellular ends of the human GABA(C) rho 1 receptor M2 domain on picrotoxinin activity', European Journal of Pharmacology, vol. 580, pp. 27 - 35, http://dx.doi.org/10.1016/j.ejphar.2007.10.036
    Journal articles | 2007
    Dr Jane Ellen Carland
    Deeb T; Carland JE; Cooper MA; Livesey M; Lambert J; Peters J; Hales T, 2007, 'Dynamic modification of a mutant cytoplasmic residue modulates the conductance of the human 5-HT3A receptor', The Journal of Biological Chemistry, vol. 282, pp. 6172 - 6182, http://dx.doi.org/10.1074/jbc.M607698200
    Journal articles | 2006
    Dr Jane Ellen Carland
    Hales T; Dunlop JI; Deeb T; Carland JE; Kelley SP; Lambert J; Peters J, 2006, 'Common determinants of single channel conductance within the large cytoplasmic loop of 5-HT3 and á4â2 nicotinic acetylcholine receptors', The Journal of Biological Chemistry, vol. 281, pp. 8062 - 8071, http://dx.doi.org/10.1074/jbc.M513222200
    Journal articles | 2006
    Dr Jane Ellen Carland
    Peters J; Carland JE; Cooper MA; Livesey M; Deeb T; Hales T; Lambert J, 2006, 'Novel structural determinants of single channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors', Biochemical Society Transactions, vol. 34, pp. 882 - 886, http://dx.doi.org/10.1042/BST0340882
    Journal articles | 2005
    Dr Jane Ellen Carland
    Barker D; Lin DH-S; Carland JE; Chu CP-Y; Chebib M; Brimble MA; Savage GP; McLeod MD, 2005, 'Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors', Bioorganic and Medicinal Chemistry, vol. 13, pp. 4565 - 4575, http://dx.doi.org/10.1016/j.bmc.2005.04.054
    Journal articles | 2004
    Dr Jane Ellen Carland
    Carland JE; Moore AM; Hanrahan JR; Mewett KN; Duke RK; Johnston G; Chebib M, 2004, 'Mutations of the 2' proline in the M2 domain of the human GABAC ĉ1 subunit alter agonist responses', Neuropharmacology, vol. 46, pp. 770 - 781, http://dx.doi.org/10.1016/j.neuropharm.2003.11.027
    Journal articles | 2004
    Dr Jane Ellen Carland
    Carland JE; Moorhouse AJ; Barry PH; Johnston G; Chebib M, 2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, vol. 279, pp. 54153 - 54160, http://dx.doi.org/10.1074/jbc.M410625200
  • Reports | 2017
    Dr Jane Ellen Carland
    Kumar SS; Graham GG; Smith FC; Furlong TJ; Greenfield JR; Stocker SS; Carland JE; Day RO, 2017, Could metformin be used in patients with advanced chronic kidney disease?, http://dx.doi.org/10.1111/dom.12806
  • Conference Abstracts | 2019
    Dr Jane Ellen Carland
    Shingde R; Graham G; Reuter S; Carland J; Williams K; Day R; Stocker S, 2019, 'PREDICTIVE PERFORMANCE OF A COMMERCIAL BAYESIAN FORECASTING PROGRAM IN ESTIMATING VANCOMYCIN DRUG EXPOSURE.', in CLINICAL PHARMACOLOGY & THERAPEUTICS, WILEY, Washington, DC, Vol. 105, pp. S38 - S38, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Washington, DC, 13 March 2019 - 16 March 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000458561100115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Jane Ellen Carland
    Stocker SL; Carland JE; Moran MA; Tang S; Li CY; Alin JS; Gilbey T; Graham GG; Williams KM; Marriott DJ; Day RO, 2018, 'A CLINICAL EVALUATION OF VANCOMYCIN DOSING AND MONITORING.', in CLINICAL PHARMACOLOGY & THERAPEUTICS, WILEY, Orlando, FL, Vol. 103, pp. S88 - S88, presented at 119th Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT) - Breaking Down Barriers to Effective Patient Care, Orlando, FL, 21 March 2018 - 24 March 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000424997100316&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Dr Jane Ellen Carland
    Kamel B; Stocker S; Graham G; Carland J; Parker M; Williams K; Pile K; Portek I; McGill N; Day R, 2017, 'A MULTICENTRE OPEN-LABEL PHARMACOKINETIC-PHARMACODYNAMIC (PKPD) STUDY OF FEBUXOSTAT IN PATIENTS WITH CHRONIC GOUT', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 47, pp. 14 - 14, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000400304400034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2009
    Dr Jane Ellen Carland
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'Do divalent cations increase the anion-cation permeability in glycine receptor channels, even with initial offset and activity corrections?', Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Sciences, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102616&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Dr Jane Ellen Carland
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels', presented at Curtin Conference, RMIT, Melbourne, VIC, 15 April 2009 - 17 April 2009
    Conference Posters | 2009
    Dr Jane Ellen Carland
    Moorhouse A; Carland JE; Cooper MA; Sugiharto S; Jeong H-J; Lewis TM; Barry PH; Peters JA; Lambert JJ, 2009, 'Molecular determinants of ion permeation in glycine receptor-channels: characterising charged residues in the intracellular M3-M4 loop', Kyoto, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Societies, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102614&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Presentations | 2009
    Dr Jane Ellen Carland
    Barry PH; Sugiharto S; Carland JE; Moorhouse AJ; Lewis TM, 2009, 'Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets', presented at 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, 29 November 2009
    Conference Presentations | 2008
    Dr Jane Ellen Carland
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'The role of intracellular portals in glycine receptor ion permeation', presented at 32nd Annual Meeting of the Australian Society for Biophysics, Australian National University, Canberra, Australia, 28 September 2008 - 01 October 2008
    Conference Presentations | 2008
    Dr Jane Ellen Carland
    Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'Charged residues in the intracellular loop affect the conductance of glycine α1 receptors', presented at Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, 12 November 2008 - 14 November 2008
    Conference Papers | 2008
    Dr Jane Ellen Carland
    Barry PH; Sugiharto S; Carland JE; Lewis TM; Schofield PR; Moorhouse AJ, 2008, 'External divalent ions increase anion-cation permeability in glycine receptor channels – consideration of ion activities, surface charge and conductance measurements', in Proceedings of the Australian Physiological and Pharmacological Society, Australian Physiological and Pharmacological Society Conference 2008, presented at Australian Physiological and Pharmacological Society Conference 2008

Awards

2019    UNSW Arc Research Supervisor Award

2014    BPS/ASCEPT Outstanding Young Investigator Prize

2014    ASCEPT Denis Wade Johnson and Johnson New Investigator Award

2012    Rebecca L. Cooper Medical Research Foundation Medal

2012    Presentation Award, Membrane Transporters Workshop

2010    Paper of the Month (June), School of Medical Sciences, UNSW

2009    Awarded UNSW School of Medical Sciences New Researcher of the Year 
2009    Awarded UNSW Faculty of Medicine, Dean’s Rising Star Award
2009    Paper of the Month (January), School of Medical Sciences, UNSW
2008    Awarded a place at the Australian Course in Advanced Neuroscience
2001    Australian Postgraduate Award
2000    University Medal, University of Sydney
2000    Wheelan Prize, ASCEPT Honours Student Poster Presentation
2000    Highly commended, Tocris Neuropharmacology Poster Prize
1999    National Institute of Schizophrenia and Allied Disorders (NISAD) Summer Student Scholarship, 
1999    Roland H Thorp Prize in Pharmacology
1997-1999    Dean’s List, University of Sydney
 

Grants

2018    St Vincent’s Curran Foundation Endowment Award ($35,000) “Metabolomics of Metformin in Heart Failure” (Carland JE, Stocker SL, Chowdhury G)


2018    St Vincent’s Curran Foundation Endowment Award ($30,000) “Optimising Tacrolimus Therapy in Lung Transplant Patients” (Carland JE, Stocker SL)


2017/2018    The Friends of the Mater Foundation Grant Application. ($10,000) “Pharmacokinetic factors associated with scalp cooling efficacy for docetaxel-containing regimens in cancer patients” (Boyle F, Dear R, Andrews K, Carland J, Stocker S)


2017    UNSW Research Infrastructure Scheme ($78,431) “Installation of a Shimadzu Nexera X2 UHPLC into the Department of Clinical Pharmacology and Toxicology” (Day RO, Carland JE, Stocker SL, Norris RLG, Greenfield JR)


2017    St Vincent’s Clinic Foundation Annual Research Grant ($30,000) “The safety and Pharmacokinetics of Metformin in Heart Failure” (Day R, Macdonald P, Greenfield J, Graham G, Carland J, Stocker S)


2015-2017     National Health and Medical Research Council (NHMRC) Project Grant “Novel Drugs for the Treatment of Chronic Pain” (App 1082570; Vandenberg R, O'Mara M, Imlach W, Rawling T, Carland J, Ryan R)


2013    Sydney Medical School Early Career Researcher Grant 
2008    Ian Potter Foundation Travel Grant
2008    UNSW Faculty of Medicine Early Career Researcher Grant
2008    UNSW Vice Chancellor’s Postdoctoral Research Fellow
2006    UK Brain Travel Grant
2001    Australian Postgraduate Award, University of Sydney
2000    Faculty of Medicine Honours Scholarship, University of Sydney
1999    National Institute of Schizophrenia and Allied Disorders (NISAD) Summer Student Scholarship
1997    University Entry Scholarship, University of Sydney

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