Dr Jeffrey Hamilton Stear

Gell C; Bormuth V; Brouhard GJ; Cohen DN; Diez S; Friel CT; Helenius J; Nitzsche B; Petzold H; Ribbe J; Schäffer E; Stear JH; Trushko A; Varga V; Widlund PO; Zanic M; Howard J, 2010, Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy, C, http://dx.doi.org/10.1016/S0091-679X(10)95013-9

Böcking T; Jacques DA; Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y, 2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, vol. 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250

Wang Y; Stear JH; Swain A; Xu X; Bryce NS; Carnell M; Alieva IB; Dugina VB; Cripe TP; Stehn J; Hardeman EC; Gunning PW, 2020, 'Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects', Molecular Cancer Research, vol. 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122

Patkunarajah A; Stear JH; Moroni M; Schroeter L; Blaszkiewicz J; Tearle JLE; Cox CD; Fuerst C; Sánchez-Carranza O; Fernández MDÁO; Fleischer R; Eravci M; Weise C; Martinac B; Biro M; Lewin GR; Poole K, 2020, 'TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.', eLife, vol. 9, http://dx.doi.org/10.7554/eLife.53308

Meiring JCM; Bryce NS; Lastra Cagigas M; Benda A; Whan RM; Ariotti N; Parton RG; Stear JH; Hardeman EC; Gunning PW, 2019, 'Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres', Journal of cell science, vol. 132, http://dx.doi.org/10.1242/jcs.228916

Meiring JCM; Bryce NS; Wang Y; Taft MH; Manstein DJ; Liu Lau S; Stear J; Hardeman EC; Gunning PW, 2018, 'Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton', Current Biology, vol. 28, pp. 2331 - 2337.e5, http://dx.doi.org/10.1016/j.cub.2018.05.053

Ferreira J; Stear JH; Saumweber H, 2017, 'Nucleoporins NPP-10, NPP-13 and NPP-20 are required for HCP-4 nuclear import to establish correct centromere assembly', Journal of Cell Science, vol. 130, pp. 963 - 974, http://dx.doi.org/10.1242/jcs.196709

Appaduray MA; Masedunskas A; Bryce NS; Lucas CA; Warren SC; Timpson P; Stear JH; Gunning PW; Hardeman EC, 2016, 'Recruitment kinetics of tropomyosin tpm3.1 to actin filament bundles in the cytoskeleton is independent of actin filament kinetics', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0168203

Casas-Delucchi CS; Van Bemmel JG; Haase S; Herce HD; Nowak D; Meilinger D; Stear JH; Leonhardt H; Cardoso MC, 2012, 'Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin', Nucleic Acids Research, vol. 40, pp. 159 - 169, http://dx.doi.org/10.1093/nar/gkr723

Widlund PO; Stear JH; Pozniakovsky A; Zanic M; Reber S; Brouhard GJ; Hyman AA; Howard J, 2011, 'XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region', Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 2741 - 2746, http://dx.doi.org/10.1073/pnas.1016498108

Chagin VO; Stear JH; Cardoso MC, 2010, 'Organization of DNA replication.', Cold Spring Harbor perspectives in biology, vol. 2, http://dx.doi.org/10.1101/cshperspect.a000737

Zanic M; Stear JH; Hyman AA; Howard J, 2009, 'EB1 recognizes the nucleotide state of tubulin in the microtubule lattice', PLoS ONE, vol. 4, http://dx.doi.org/10.1371/journal.pone.0007585

Brouhard GJ; Stear JH; Noetzel TL; Al-Bassam J; Kinoshita K; Harrison SC; Howard J; Hyman AA, 2008, 'XMAP215 Is a Processive Microtubule Polymerase', Cell, vol. 132, pp. 79 - 88, http://dx.doi.org/10.1016/j.cell.2007.11.043

Görisch SM; Sporbert A; Stear JH; Grunewald I; Nowak D; Warbrick E; Leonhardt H; Cardoso MC, 2008, 'Uncoupling the replication machinery: Replication fork progression in the absence of processive DNA synthesis', Cell Cycle, vol. 7, pp. 1983 - 1990, http://dx.doi.org/10.4161/cc.7.13.6094

Stear JH; Roth MB, 2004, 'The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli', Molecular Biology of the Cell, vol. 15, pp. 5187 - 5196, http://dx.doi.org/10.1091/mbc.E04-06-0486

Stear JH; Roth MB, 2002, 'Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment', Genes and Development, vol. 16, pp. 1498 - 1508, http://dx.doi.org/10.1101/gad.989102

Gunning P; Wang Y; Stear JH; Swain A; Xu X; Bryce N; Alieva IB; Dugina VB; Cripe T; Stehn J; Hardeman EC, 2020, 'Anti-tropomyosin drugs prevent the rescue of vincristine-induced mitotic spindle defects', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5817

Meiring JC; Bryce NS; Stear JH; Hardeman EC; Gunning PW, 2017, 'The tropomyosin isoform composition of cellular actin filaments is not a simple function of relative isoform abundance.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wang Y; Swain A; Stear JH; Bryce NS; Dugina VB; Alieva IB; Cripe TP; Stehn JR; Hardeman EC; Gunning PW, 2017, 'Synergy between anti-tropomyosin and anti-microtubule drugs reveals an interaction between actin and microtubule networks.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), Philadelphia, PA, 02 December 2017 - 06 December 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301293&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Poole K; Wetzel C; Stear JH; Moroni M; Lewin GR, 2016, 'Tuning PIEZO ion channels to detect molecular-scale movements relevant for fine touch', presented at ComBIO, Brisbane, 03 October 2016 - 07 October 2016

Stear JH; Loerke D; Chagin V; Leonhardt H; Cardoso MC, 2011, 'DNA replication machinery clamps down on chromatin mobility', in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, SPRINGER, Budapest, HUNGARY, pp. 99 - 99, presented at 8th EBSA European Biophysics Congress, Budapest, HUNGARY, 23 August 2011 - 27 August 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293637300216&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Delucchi CSC; Nowak D; Cardoso MC; Stear JH; Chagin VO; van Bemmel J; Haase S, 2009, 'EPIGENETIC CONTROL OF HETEROCHROMATIN REPLICATION', in CELLULAR ONCOLOGY, SPRINGER, Edinburgh, SCOTLAND, pp. 98 - 99, presented at 3rd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), Edinburgh, SCOTLAND, 01 April 2009 - 05 April 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265635300022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Delucchi CSC; Bernmel van J; Chagin VO; Nowak D; Stear JH; Cardoso MC, 2008, 'Epigenetic control of heterochromatin replication', in CELLULAR ONCOLOGY, SPRINGER, Madrid, SPAIN, pp. 250 - 251, presented at 2nd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), Madrid, SPAIN, 04 May 2008 - 07 May 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255341800046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y; Böcking T; Jacques DA, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, http://dx.doi.org/10.1101/2020.11.13.382242

Böcking T; Jacques DA; Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y, 2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, vol. 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250

Patkunarajah A; Stear JH; Moroni M; Schroeter L; Blaszkiewicz J; Tearle JLE; Cox CD; Fuerst C; Sánchez-Carranza O; Fernández MDÁO; Fleischer R; Eravci M; Weise C; Martinac B; Biro M; Lewin GR; Poole K, 2020, 'TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.', eLife, vol. 9, http://dx.doi.org/10.7554/eLife.53308

Wang Y; Stear JH; Swain A; Xu X; Bryce NS; Carnell M; Alieva IB; Dugina VB; Cripe TP; Stehn J; Hardeman EC; Gunning PW, 2020, 'Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects', Molecular Cancer Research, vol. 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122

Meiring JCM; Bryce NS; Lastra Cagigas M; Benda A; Whan RM; Ariotti N; Parton RG; Stear JH; Hardeman EC; Gunning PW, 2019, 'Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres', Journal of cell science, vol. 132, http://dx.doi.org/10.1242/jcs.228916

Meiring JCM; Bryce NS; Wang Y; Taft MH; Manstein DJ; Liu Lau S; Stear J; Hardeman EC; Gunning PW, 2018, 'Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton', Current Biology, vol. 28, pp. 2331 - 2337.e5, http://dx.doi.org/10.1016/j.cub.2018.05.053

Ferreira J; Stear JH; Saumweber H, 2017, 'Nucleoporins NPP-10, NPP-13 and NPP-20 are required for HCP-4 nuclear import to establish correct centromere assembly', Journal of Cell Science, vol. 130, pp. 963 - 974, http://dx.doi.org/10.1242/jcs.196709

Appaduray MA; Masedunskas A; Bryce NS; Lucas CA; Warren SC; Timpson P; Stear JH; Gunning PW; Hardeman EC, 2016, 'Recruitment kinetics of tropomyosin tpm3.1 to actin filament bundles in the cytoskeleton is independent of actin filament kinetics', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0168203

Casas-Delucchi CS; Van Bemmel JG; Haase S; Herce HD; Nowak D; Meilinger D; Stear JH; Leonhardt H; Cardoso MC, 2012, 'Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin', Nucleic Acids Research, vol. 40, pp. 159 - 169, http://dx.doi.org/10.1093/nar/gkr723

Widlund PO; Stear JH; Pozniakovsky A; Zanic M; Reber S; Brouhard GJ; Hyman AA; Howard J, 2011, 'XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region', Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 2741 - 2746, http://dx.doi.org/10.1073/pnas.1016498108

Chagin VO; Stear JH; Cardoso MC, 2010, 'Organization of DNA replication.', Cold Spring Harbor perspectives in biology, vol. 2, http://dx.doi.org/10.1101/cshperspect.a000737

Zanic M; Stear JH; Hyman AA; Howard J, 2009, 'EB1 recognizes the nucleotide state of tubulin in the microtubule lattice', PLoS ONE, vol. 4, http://dx.doi.org/10.1371/journal.pone.0007585

Brouhard GJ; Stear JH; Noetzel TL; Al-Bassam J; Kinoshita K; Harrison SC; Howard J; Hyman AA, 2008, 'XMAP215 Is a Processive Microtubule Polymerase', Cell, vol. 132, pp. 79 - 88, http://dx.doi.org/10.1016/j.cell.2007.11.043

Görisch SM; Sporbert A; Stear JH; Grunewald I; Nowak D; Warbrick E; Leonhardt H; Cardoso MC, 2008, 'Uncoupling the replication machinery: Replication fork progression in the absence of processive DNA synthesis', Cell Cycle, vol. 7, pp. 1983 - 1990, http://dx.doi.org/10.4161/cc.7.13.6094

Stear JH; Roth MB, 2004, 'The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli', Molecular Biology of the Cell, vol. 15, pp. 5187 - 5196, http://dx.doi.org/10.1091/mbc.E04-06-0486

Stear JH; Roth MB, 2002, 'Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment', Genes and Development, vol. 16, pp. 1498 - 1508, http://dx.doi.org/10.1101/gad.989102