Dr Jeffrey Stear

Books

Books | 2010

Gell C; Bormuth V; Brouhard GJ; Cohen DN; Diez S; Friel CT; Helenius J; Nitzsche B; Petzold H; Ribbe J; SchÃ¤ffer E; Stear JH; Trushko A; Varga V; Widlund PO; Zanic M; Howard J, 2010, Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy, C, http://dx.doi.org/10.1016/S0091-679X(10)95013-9

Book Chapters

Edited Books

Journal Articles

Journal articles | 2022

2022, 'Insights into HIV uncoating from single-particle imaging techniques', Biophysical Reviews, 14, pp. 23 - 32, http://dx.doi.org/10.1007/s12551-021-00922-6

Journal articles | 2021

2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250

Journal articles | 2020

2020, 'Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects', Molecular Cancer Research, 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122

Journal articles | 2020

2020, 'TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.', eLife, 9, http://dx.doi.org/10.7554/eLife.53308

Journal articles | 2019

2019, 'Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres', Journal of Cell Science, 132, http://dx.doi.org/10.1242/jcs.228916

Journal articles | 2018

Meiring JC M; Bryce NS; Wang Y; Taft MH; Manstein DJ; Liu Lau S; Stear J; Hardeman EC; Gunning PW, 2018, 'Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton', Current Biology, 28, pp. 2331 - 2337.e5, http://dx.doi.org/10.1016/j.cub.2018.05.053

Journal articles | 2017

Ferreira J; Stear JH; Saumweber H, 2017, 'Nucleoporins NPP-10, NPP-13 and NPP-20 are required for HCP-4 nuclear import to establish correct centromere assembly', Journal of Cell Science, 130, pp. 963 - 974, http://dx.doi.org/10.1242/jcs.196709

Journal articles | 2016

Appaduray MA; Masedunskas A; Bryce NS; Lucas CA; Warren SC; Timpson P; Stear JH; Gunning PW; Hardeman EC, 2016, 'Recruitment kinetics of tropomyosin tpm3.1 to actin filament bundles in the cytoskeleton is independent of actin filament kinetics', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0168203

Journal articles | 2012

Casas-Delucchi CS; Van Bemmel JG; Haase S; Herce HD; Nowak D; Meilinger D; Stear JH; Leonhardt H; Cardoso MC, 2012, 'Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin', Nucleic Acids Research, 40, pp. 159 - 169, http://dx.doi.org/10.1093/nar/gkr723

Journal articles | 2011

Widlund PO; Stear JH; Pozniakovsky A; Zanic M; Reber S; Brouhard GJ; Hyman AA; Howard J, 2011, 'XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region', Proceedings of the National Academy of Sciences of the United States of America, 108, pp. 2741 - 2746, http://dx.doi.org/10.1073/pnas.1016498108

Journal articles | 2010

Chagin VO; Stear JH; Cardoso MC, 2010, 'Organization of DNA replication.', Cold Spring Harbor perspectives in biology, 2, http://dx.doi.org/10.1101/cshperspect.a000737

Journal articles | 2009

Zanic M; Stear JH; Hyman AA; Howard J, 2009, 'EB1 recognizes the nucleotide state of tubulin in the microtubule lattice', PLoS ONE, 4, http://dx.doi.org/10.1371/journal.pone.0007585

Journal articles | 2008

Brouhard GJ; Stear JH; Noetzel TL; Al-Bassam J; Kinoshita K; Harrison SC; Howard J; Hyman AA, 2008, 'XMAP215 Is a Processive Microtubule Polymerase', Cell, 132, pp. 79 - 88, http://dx.doi.org/10.1016/j.cell.2007.11.043

Journal articles | 2008

GÃ¶risch SM; Sporbert A; Stear JH; Grunewald I; Nowak D; Warbrick E; Leonhardt H; Cardoso MC, 2008, 'Uncoupling the replication machinery: Replication fork progression in the absence of processive DNA synthesis', Cell Cycle, 7, pp. 1983 - 1990, http://dx.doi.org/10.4161/cc.7.13.6094

Journal articles | 2004

Stear JH; Roth MB, 2004, 'The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli', Molecular Biology of the Cell, 15, pp. 5187 - 5196, http://dx.doi.org/10.1091/mbc.E04-06-0486

Journal articles | 2002

Stear JH; Roth MB, 2002, 'Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment', Genes and Development, 16, pp. 1498 - 1508, http://dx.doi.org/10.1101/gad.989102

Working Papers

Other

Preprints | 2023

2023, Replisome loading reduces chromatin motion independent of DNA synthesis, , http://dx.doi.org/10.1101/2023.03.07.531331

Conference Papers | 2020

2020, 'Anti-tropomyosin drugs prevent the rescue of vincristine-induced mitotic spindle defects', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5817

Preprints | 2020

2020, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, , http://dx.doi.org/10.1101/2020.11.13.382242

Conference Abstracts | 2017

Meiring JC; Bryce NS; Stear JH; Hardeman EC; Gunning PW, 2017, 'The tropomyosin isoform composition of cellular actin filaments is not a simple function of relative isoform abundance.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, PA, Philadelphia, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), PA, Philadelphia, 02 December 2017 - 06 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2017

Wang Y; Swain A; Stear JH; Bryce NS; Dugina VB; Alieva IB; Cripe TP; Stehn JR; Hardeman EC; Gunning PW, 2017, 'Synergy between anti-tropomyosin and anti-microtubule drugs reveals an interaction between actin and microtubule networks.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, PA, Philadelphia, Vol. 28, presented at Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO), PA, Philadelphia, 02 December 2017 - 06 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426664301293&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations | 2016

Poole K; Wetzel C; Stear JH; Moroni M; Lewin GR, 2016, 'Tuning PIEZO ion channels to detect molecular-scale movements relevant for fine touch', presented at ComBIO, Brisbane, 03 October 2016 - 07 October 2016

Conference Papers | 2011

Stear JH; Loerke D; Chagin V; Leonhardt H; Cardoso MC, 2011, 'DNA replication machinery clamps down on chromatin mobility', in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, SPRINGER, HUNGARY, Budapest, pp. 99 - 99, presented at 8th EBSA European Biophysics Congress, HUNGARY, Budapest, 23 August 2011 - 27 August 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293637300216&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2009

Delucchi CS C; Nowak D; Cardoso MC; Stear JH; Chagin VO; van Bemmel J; Haase S, 2009, 'EPIGENETIC CONTROL OF HETEROCHROMATIN REPLICATION', in CELLULAR ONCOLOGY, SPRINGER, SCOTLAND, Edinburgh, pp. 98 - 99, presented at 3rd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), SCOTLAND, Edinburgh, 01 April 2009 - 05 April 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265635300022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2008

Delucchi CS C; Bernmel van J; Chagin VO; Nowak D; Stear JH; Cardoso MC, 2008, 'Epigenetic control of heterochromatin replication', in CELLULAR ONCOLOGY, SPRINGER, SPAIN, Madrid, pp. 250 - 251, presented at 2nd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD), SPAIN, Madrid, 04 May 2008 - 07 May 2008, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255341800046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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Dr Jeffrey Stear