Doctor of Philosophy (Biomedical Engineering) (2015 – 2019), University of New South Wales, Sydney, Australia
Master of Biomedical Engineering (by research) (2009-2011), University of New South Wales, Sydney, Australia
Bachelor of Biomedical Engineering (2003 – 2007), Capital Medical University, Beijing, China
Dr Jingjing Li is a Postdoctoral Fellow at the Graduate School of Biomedical Engineering. She is working with A/Prof Robert Nordon on a CRC-P project developing an automated microscale bioreactor for cell and gene therapy. Her research is at the interface of biology and engineering, focusing on the development of microfluidic organ on chip systems and their application in stem cell science, cardiovascular and blood development.
Being trained as a biomedical engineer, she developed multidiscipline skills spans from microfluidics, stem cell biology, and bioinformatics. Her PhD and Post-Doctoral research focus on studying the influence of pulsatile fluid shear stress on human embryonic blood formation using microfluidic model mimicking foetal circulation, live cell imaging of hPSC differentiation and single-cell RNA sequencing of developing blood niches. She is now working on upscaling the microfluidic organ-on-a-chip models and applying them in the expansion, maturation and engraftment of blood stem and progenitor cells generated from human pluripotent stem cells (hPSCs).
CIA, Early Career Researcher Seed Grant ,UNSW Engineering Faculty (2021)
CIA, International Seed Grant, UNSW Engineering Faculty (2022)
Scaling microfluidics for cell manufacture. Australian Research Council Linkage Grant LP160100570 (2016-2019)
1. Modelling human heart and blood development from pluripotent stem cells on a microfluidic chip
We have used lab-on-chip to mimic foetal circulation and to model human blood formation from cells that line blood vessels. We are currently studying the influence of pulsatile blood flow and circulation on the generation of precursor blood stem cells. We are also investigating the use of hydrogels to pattern embryonic development of the cardiovascular system.
2. Enhancing the development of blood stem cell from pluripotent stem cells using dynamic culture system
We use upscaled Microfluidic circulation system and orbital shearing culture system to enhance the development of precursor blood stem cells. This work has been featured in UNSW newsroom and The conversation.
3. Expansion, maturation and engraftment of hPSC derived CD34+ blood stem cell precursor and CD34+ blood stem cells isolated from cord blood and mobilised peripharal blood.
International Society of Stem Cell Research (ISSCR)
International Society of Experimental Hematology (ISEH), New investigator committee member
International Society of Cell Therapy (ISCT)
IEEE Medical Imaging and Image processing
IEEE Engineering in Medicine & Biology Society (EMBS)
Australia Society of Stem Cell Research (ASSCR)
NSW Stem Cell Network
UNSW Cardiac, Vascular & Metabolic Medicine Theme (CVMM), Early career researcher committee member
Level 3 WHS committee, Graduate School of Biomedical Engineering, UNSW
BIOM9640 Biomedical Instrumentation