Dr Jingjing Li
Postdoctoral Fellow

Dr Jingjing Li

Doctor of Philosophy (Biomedical Engineering) (2015 – 2019), University of New South Wales, Sydney, Australia

Master of Biomedical Engineering (by research) (2009-2011), University of New South Wales, Sydney, Australia

Bachelor of Biomedical Engineering (2003 – 2007), Capital Medical University, Beijing, China

 

 

Engineering
Grad Sch: Biomedical Eng

Dr Jingjing Li is a  Postdoctoral Fellow at the Graduate School of Biomedical Engineering. She is working with A/Prof Robert Nordon on a CRC-P project developing an automated microscale bioreactor for cell and gene therapy. Her research is at the interface of biology and engineering, focusing on the development of microfluidic organ on chip systems and their application in stem cell science, cardiovascular and blood development. 

Being trained as a biomedical engineer, she developed multidiscipline skills spans from microfluidics, stem cell biology, and bioinformatics. Her PhD and Post-Doctoral research focus on studying the influence of pulsatile fluid shear stress on human embryonic blood formation using microfluidic model mimicking foetal circulation, live cell imaging of hPSC differentiation and single-cell RNA sequencing of developing blood niches. She is now working on upscaling the microfluidic organ-on-a-chip models and applying them in the expansion, maturation and engraftment of blood stem and progenitor cells generated from human pluripotent stem cells (hPSCs).

Location
Samuels 514, F25 UNSW Sydney Kensington 2052
  • Journal articles | 2020
    Cornwell JA; Li J; Mahadevan S; Draper JS; Joun GL; Zoellner H; Asli NS; Harvey RP; Nordon RE, 2020, 'TrackPad: Software for semi-automated single-cell tracking and lineage annotation', SoftwareX, vol. 11, http://dx.doi.org/10.1016/j.softx.2020.100440
  • Conference Abstracts | 2019
    Li J; Bruveris F; Ed S; Elefanty A; Lao O; Ng E; Nordon R; Ralph P, 2019, 'THE ROLE OF SHEAR STRESS IN THE GENERATION OF DEFINITIVE HAEMATOPOIETIC LINEAGES AND ARTERIAL VASCULATURE FROM HUMAN PLURIPOTENT STEM CELLS AT THE SINGLE-CELL LEVEL', in EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, Vol. 76, pp. S73 - S74, http://dx.doi.org/10.1016/j.exphem.2019.06.390

CIA, Early Career Researcher Seed Grant ,UNSW Engineering Faculty (2021)

CIA, International Seed Grant, UNSW Engineering Faculty (2022)

Contributor for  

Scaling microfluidics for cell manufacture. Australian Research Council Linkage Grant LP160100570 (2016-2019)

CRC-P "Making cell and gene therapy affordable with a microbioreactor" UNSW, Genesys, CSL (2021-2023)

  • ASSCR-AGCTS 2022 Joint Scientific Meeting Travel Award                                        2022
  • ASSCR-AGCTS-ISCT 2019 Joint Scientific Meeting Travel Award                              2019
  • International Society of Experimental Hematology Conference Award                          2019
  • "Best Poster Presentation Award" UNSW Cross Faculty Research Symposium             2019
  • Postdoctoral Writing Fellow                                                                                             2018
  • International Society of Stem Cell Research Conference Award                                      2018
  • Australia Society for Stem Cell Research Conference Award                                           2017
  • Stem Cell Australia (SCA) Meeting Travel Award                                                  2015-2017
  • Women in Engineering Award, UNSW                                                                    2015-2019
  • Faculty Top-up Scholarship, UNSW, Engineering                                                   2015-2019
  • Australia Postgraduate Award                                                                                   2015-2019
  • Australia Society for Stem Cell Research Conference Award                                            2010

 

1. Modelling human heart and blood development from pluripotent stem cells on a microfluidic chip

We have used lab-on-chip to mimic foetal circulation and to model human blood formation from cells that line blood vessels. We are currently studying the influence of pulsatile blood flow and circulation on the generation of precursor blood stem cells. We are also investigating the use of hydrogels to pattern embryonic development of the cardiovascular system.

2. Enhancing the development of blood stem cell from pluripotent stem cells using dynamic culture system

We use upscaled Microfluidic circulation system and orbital shearing culture system to enhance the development of precursor blood stem cells. This work has been featured in UNSW newsroom and The conversation.

3. Expansion, maturation and engraftment of hPSC derived CD34+ blood stem cell precursor and CD34+ blood stem cells isolated from cord blood and mobilised peripharal blood.

 

Research Society and Committee

International Society of Stem Cell Research (ISSCR)

International Society of Experimental Hematology (ISEH), New investigator committee member

International Society of Cell Therapy (ISCT)

IEEE Medical Imaging and Image processing

IEEE Engineering in Medicine & Biology Society (EMBS)

Australia Society of Stem Cell Research (ASSCR)

Engineers Australia

NSW Stem Cell Network

UNSW Cardiac, Vascular & Metabolic Medicine Theme (CVMM), Early career researcher committee member

Professional Society

Level 3 WHS committee, Graduate School of Biomedical Engineering, UNSW

 

My Teaching

BIOM9640 Biomedical Instrumentation