Dr Jingjing Li
Postdoctoral Fellow
Doctor of Philosophy (Biomedical Engineering) (2015 – 2019), University of New South Wales, Sydney, Australia
Master of Biomedical Engineering (by research) (2009-2011), University of New South Wales, Sydney, Australia
Bachelor of Biomedical Engineering (2003 – 2007), Capital Medical University, Beijing, China
Engineering
Grad Sch: Biomedical Eng
Dr Jingjing Li is a Postdoctoral Fellow at the Graduate School of Biomedical Engineering. She is working with A/Prof Robert Nordon on ARC Linkage and CRC-P project developing an automated microscale bioreactor for cell and gene therapy. Her research is at the interface of biology and engineering, focusing on the development of microfluidic organ on chip systems and their application in stem cell science, cardiovascular and blood development.
Being trained as a biomedical engineer, she developed multidiscipline skills spans from microfluidics, stem cell biology, and bioinformatics. Her PhD and Post-Doctoral research focus on studying the influence of pulsatile fluid shear stress on human embryonic blood formation using microfluidic model mimicking foetal circulation, live cell imaging of hPSC differentiation and single-cell RNA sequencing of developing blood niches. She is now working on upscaling the microfluidic organ-on-a-chip models and applying them in the expansion, maturation and engraftment of blood stem and progenitor cells.
E-mail
Location
Samuels 514, F25
UNSW Sydney
Kensington
2052
- Publications
- Media
- Grants
- Awards
- Research Activities
- Engagement
- Teaching and Supervision
CIA, Early Career Researcher Seed Grant ,UNSW Engineering Faculty (2021)
CIA, International Seed Grant, UNSW Engineering Faculty (2022)
Contributor for
Scaling microfluidics for cell manufacture. Australian Research Council Linkage Grant LP160100570 (2016-2019)
Manufacturing 3D microstructures for the medical device industry. Australian Research Council Linkage Grant LP160100573 (2016-2019)
Travel Grants
2022 The Australasian Society for Stem Cell Research (ASSCR) and the Australasian Gene and Cell Therapy Society (AGCTS) Joint Scientific Meeting / National Stem Cell Foundation of Australia (NSCFA) Travel Award
2019 The Australasian Society for Stem Cell Research (ASSCR) and the Australasian Gene and Cell Therapy Society (AGCTS) Joint Scientific Meeting / National Stem Cell Foundation of Australia (NSCFA) Travel Award
2019 International Society of Experimental Hematology Conference Award
2018 International Society of Stem Cell Research ECR and student Conference Award
2017 Australian Society for Stem Cell Research ECR and student Conference Award
2015-2017 Stem Cell Australia (SCA) Meeting Travel Grant
2010 Australian Society for Stem Cell Research (ASSCR) Conference Travel Award
Scholarship, Awards and Fellowship:
2019 Best Poster Presentation Award, UNSW Cross Faculty Research Symposium
2018-2019 Postdoctoral Writing Fellow Award, UNSW
2015-2019 Women in Engineering Award, UNSW
2015-2019 Faculty Top-up Scholarship, UNSW, Engineering
2015-2019 Australia Postgraduate Award
1. Modelling human heart, vascular and blood development from pluripotent stem cells on a microfluidic chip
We have used lab-on-chip to mimic foetal circulation and to model human blood formation from cells that line blood vessels. We are currently studying the influence of pulsatile blood flow and circulation on the generation of precursor blood stem cells. We are also investigating the use of hydrogels to pattern embryonic development of the cardiovascular system.
2. Enhancing the development of aortic vasculature and blood stem cell from pluripotent stem cells using dynamic culture system
We use upscaled Microfluidic circulation system and orbital shearing culture system to enhance the development of precursor blood stem cells. This work has been featured in UNSW newsroom and The conversation.
3. Stem cell engineering: the modification of human CD34+ blood stem and progenitor cells.
CD34+ blood stem and progenitor cells derived from sources such as cord blood, bone marrow, mobilised peripheral blood, and human pluripotent stem cells can be manipulated through various techniques of separation, stimulation and genetic modification. These modifications target the genetic or physical traits of the cells with the goal of improving their functionality, therapeutic potential, and compatibility for diverse applications in the field of medicine, particularly in the realm of haematopoietic stem cell and gene therapy.
Research Society and Committee
International Society of Stem Cell Research (ISSCR)
International Society of Experimental Hematology (ISEH) - New Investigator Committee (NIC) Member
International Society of Cell Therapy (ISCT) - Stem Cell Engineering Committee Member (Committee Spotlight)
UNSW Cardiac, Vascular & Metabolic Medicine Theme (CVMM) - Early Career Researcher Committee Member
IEEE Medical Imaging and Image processing
IEEE Engineering in Medicine & Biology Society (EMBS)
Australia Society of Stem Cell Research (ASSCR)
Engineers Australia
NSW Stem Cell Network
Professional Society
Academic Representative, Level 3 WHS committee, Graduate School of Biomedical Engineering, UNSW
My Research Supervision
Co-supervising PhD Candidate:
Ada Lee, Lab-on-a-chip scale-out of autologous cell and gene therapies.
My Teaching
BIOM9640 Biomedical Instrumentation
BIOM1010 Engineering in Medicine and Biology