Ms Jingjing You
Visiting Fellow

Ms Jingjing You

Medicine & Health
School of Optometry

My research area focused on corneal bioengineering, bioink development and investigations on etiology of corneal diseases. Our research has identified key pathways involved in keratoconus, two novel bioink for corneal wound healing and a medical device for treating corneal ulceration and perforation. Our research team is continually working on finding the causes of corneal diseases, developing novel interventions to prevent and treat blindness.

I am based at Save Sight Institute, University of Sydney. I am also the co-founder of Australia Corneal Bioengineering Working Group; member of the University of Wollongong 3D printing work shop, and working committee member of ANZ Human Eye Cell Atlas Consortium.
Location
School of Optometry and Vision Science
  • Book Chapters | 2013
    You J; Cozzi PJ; Fitzgerald A; Walsh B; Russell PJ; Willcox M; Graham P; Li Y, 2013, 'Tear as a source of protein biomarkers for human disease diagnosis and prognosis', in Makowski G (ed.), Tear as a source of protein biomarkers for human disease diagnosis and prognosis
    Book Chapters | 2012
    You J; Cozzi PJ; Fitzgerald A; Walsh B; Russell ; Willcox MD; Li Y, 2012, 'Prostate Cancer Biomarkers and the Emerging Proteomic Techniques Used in Biomarker Research', in Watanabe HS (ed.), Horizons in Cancer Research Vol 47, edn. First, Nova Science Publishers Inc, New York, pp. 1 - 36, https://www.novapublishers.com/catalog/product_info.php?products_id=27295
  • Journal articles | 2021
    You J; Corley SM; Wen L; Hodge C; Höllhumer R; Madigan MC; Wilkins MR; Sutton G, 2021, 'Author Correction: RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients (Scientific Reports, (2018), 8, 1, (389), 10.1038/s41598-017-18480-x)', Scientific Reports, vol. 11, pp. 19840, http://dx.doi.org/10.1038/s41598-021-98363-4
    Journal articles | 2021
    Song Y; Overmass M; Fan J; Hodge C; Sutton G; Lovicu FJ; You J, 2021, 'Application of Collagen I and IV in Bioengineering Transparent Ocular Tissues', Frontiers in Surgery, vol. 8, http://dx.doi.org/10.3389/fsurg.2021.639500
    Journal articles | 2021
    Petsoglou C; Wen L; Hoque M; Zhu M; Valtink M; Sutton G; You J, 2021, 'Effects of human platelet lysate on the growth of cultured human corneal endothelial cells', Experimental Eye Research, vol. 208, pp. 108613, http://dx.doi.org/10.1016/j.exer.2021.108613
    Journal articles | 2020
    Frazer H; You J; Chen Z; Sayyar S; Liu X; Taylor A; Hodge C; Wallace G; Sutton G, 2020, 'Development of a platelet lysate–based printable, transparent biomaterial with regenerative potential for epithelial corneal injuries', Translational Vision Science and Technology, vol. 9, pp. 1 - 12, http://dx.doi.org/10.1167/TVST.9.13.40
    Journal articles | 2020
    Hallett N; Yi K; Dick J; Hodge C; Sutton G; Guang Wang Y; You J, 2020, 'Deep Learning Based Unsupervised and Semi-supervised Classification for Keratoconus', Proceedings of the International Joint Conference on Neural Networks, http://dx.doi.org/10.1109/IJCNN48605.2020.9206694
    Journal articles | 2020
    Chen Z; Liu X; You J; Song Y; Tomaskovic-Crook E; Sutton G; Crook JM; Wallace GG, 2020, 'Biomimetic corneal stroma using electro-compacted collagen', Acta Biomaterialia, vol. 113, pp. 360 - 371, http://dx.doi.org/10.1016/j.actbio.2020.07.004
    Journal articles | 2020
    You J; Hodge C; Hoque M; Petsoglou C; Sutton G, 2020, 'Human platelets and derived products in treating ocular surface diseases – a systematic review', Clinical Ophthalmology, vol. 14, pp. 3195 - 3210, http://dx.doi.org/10.2147/OPTH.S265701
    Journal articles | 2018
    Chen Z; You J; Liu X; Cooper S; Hodge C; Sutton G; Crook JM; Wallace GG, 2018, 'Biomaterials for corneal bioengineering', Biomedical Materials (Bristol), vol. 13, pp. 032002, http://dx.doi.org/10.1088/1748-605X/aa92d2
    Journal articles | 2018
    You J; Corley SM; Wen L; Hodge C; Höllhumer R; Madigan MC; Wilkins MR; Sutton G, 2018, 'RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-017-18480-x
    Journal articles | 2018
    You J; Munoz-Erazo L; Wen L; Hodge C; Madigan MC; Sutton G, 2018, 'In-Vitro Effects of Secreted Frizzled-Related Protein 1 (SFRP1) On Human Corneal Epithelial Cells', Current Eye Research, vol. 43, pp. 455 - 459, http://dx.doi.org/10.1080/02713683.2018.1431284
    Journal articles | 2017
    Golebiowski B; Badarudin N; Eden J; You JJ; Hampel U; Stapleton F, 2017, 'Does endogenous serum oestrogen play a role in Meibomian gland disorder in postmenopausal women with dry eye?', British Journal of Ophthalmology, vol. 101, pp. 218 - 222, http://dx.doi.org/10.1136/bjophthalmol-2016-308473
    Journal articles | 2017
    Markoulli M; You J; Kim J; Duong CL; Tolentino JB; Karras J; Lum E, 2017, 'Corneal nerve morphology and tear film substance p in diabetes', Optometry and Vision Science, vol. 94, pp. 726 - 731, http://dx.doi.org/10.1097/OPX.0000000000001096
    Journal articles | 2017
    Markoulli M; Gokhale M; You J, 2017, 'Substance p in flush tears and schirmer strips of healthy participants', Optometry and Vision Science, vol. 94, pp. 527 - 533, http://dx.doi.org/10.1097/OPX.0000000000001040
    Journal articles | 2017
    Golebiowski B; Badarudin N; Eden J; Liu J; Gerrand L; Robinson J; Hampel U; You J; Stapleton F, 2017, 'The effects of transdermal testosterone and oestrogen therapy on dry eye in post-menopausal women: a randomised, placebo-controlled, pilot study', British Journal of Ophthalmology, vol. 101, pp. 926 - 932, http://dx.doi.org/10.1136/bjophthalmol-2016-309498
    Journal articles | 2016
    You J; Willcox M; Fitzgerald A; Schiller B; Cozzi PJ; Russell PJ; Walsh BJ; Wasinger VC; Graham PH; Li Y, 2016, 'Absolute quantification of human tear lactoferrin using multiple reaction monitoring technique with stable-isotopic labeling', Analytical Biochemistry, vol. 496, pp. 30 - 34, http://dx.doi.org/10.1016/j.ab.2015.12.006
    Journal articles | 2016
    You J; Wen L; Roufas A; Hodge C; Sutton G; Madigan MC, 2016, 'Expression of HGF and c-Met Proteins in Human Keratoconus Corneas (vol 2015, 852986, 2015)', JOURNAL OF OPHTHALMOLOGY, vol. 2016, http://dx.doi.org/10.1155/2016/4201505
    Journal articles | 2015
    You J; Wen L; Roufas A; Hodge C; Sutton G; Madigan MC, 2015, 'Expression of HGF and c-met proteins in human keratoconus corneas', Journal of Ophthalmology, vol. 2015, http://dx.doi.org/10.1155/2015/852986
    Journal articles | 2014
    Wen L; Zhu M; Madigan MC; You J; King NJC; Billson FA; McClellan K; Sutton G; Petsoglou C, 2014, 'Immunomodulatory effects of bone marrow-derived mesenchymal stem cells on pro-inflammatory cytokine-stimulated human corneal epithelial cells', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0101841
    Journal articles | 2013
    You J; Willcox MD; Madigan MC; Wasinger V; Schiller B; Walsh BJ; Graham PH; Kearsley JH; Li Y, 2013, 'Tear Fluid Protein Biomarkers', Advances in Clinical Chemistry, vol. 62, pp. 151 - 196, http://dx.doi.org/10.1016/B978-0-12-800096-0.00004-4
    Journal articles | 2013
    You J; Hodge C; Wen L; McAvoy JW; Madigan MC; Sutton G, 2013, 'Tear levels of SFRP1 are significantly reduced in keratoconus patients', Molecular Vision, vol. 19, pp. 509 - 515
    Journal articles | 2013
    You J; Wen L; Roufas A; Madigan MC; Sutton G, 2013, 'Expression of SFRP Family Proteins in Human Keratoconus Corneas', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0066770
    Journal articles | 2012
    You JJ; Madigan MC; Rowe A; Sajinovic M; Russell PJ; Jackson P, 2012, 'An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.', Urologic Oncology - Seminars and Original Investigations, vol. 30, pp. 502 - 508, http://dx.doi.org/10.1016/j.urolonc.2010.02.013
    Journal articles | 2012
    You JJ; Hodges C; Wen L; McAvoy JW; Madigan MC; Sutton G, 2012, 'Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease.', Experimental Eye Research, vol. 99, pp. 55 - 62, http://dx.doi.org/10.1016/j.exer.2012.03.012
    Journal articles | 2011
    You J; Wen L; Hodges C; Madigan M; McAvoy J; Sutton G, 2011, 'Wnt SIGNALLING PATHWAY-ASSOCIATED PROTEINS IN TEARS FROM CONTROL AND KERATOCONUS (KC) PATIENTS', CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol. 39, pp. 80 - 80, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296914400152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Graham PH; Russell PJ; Walsh B; Willcox MD; Ling Z; Wasinger VC; Li Y, 2010, 'Post-translation modification of proteins in tears', Electrophoresis, vol. 31, pp. 1853 - 1861, http://dx.doi.org/10.1002/elps.200900755
    Journal articles | 2010
    You J; Cozzi PJ; Walsh B; Willcox MD; Kearsley J; Russell PJ; Li Y, 2010, 'Innovative biomarkers for prostate cancer early diagnosis and progression', Critical Reviews in Oncology Hematology, vol. 73, pp. 10 - 22, http://dx.doi.org/10.1016/j.critrevonc.2009.02.007
    Journal articles | 2010
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Graham P; Russell PJ; Walsh BJ; Willcox M; Zhong L; Wasinger V; Li Y, 2010, 'Post-translation modification of proteins in tears', PROTEOMICS - Clinical Applications, vol. 4, pp. 870 - 870, http://dx.doi.org/10.1002/prca.201090087
    Journal articles | 2010
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Graham P; Russell PJ; Walsh B; Willcox MD; Li Y, 2010, 'Post translational modification of proteins in the tear film.', Electrophoresis, vol. 31, pp. 1853 - 1861, http://dx.doi.org/10.1002/elps.200900755
  • Preprints | 2020
    Hallett N; Yi K; Dick J; Hodge C; Sutton G; Wang YG; You J, 2020, Deep Learning Based Unsupervised and Semi-supervised Classification for Keratoconus
    Conference Abstracts | 2019
    Hallett N; Maseedupally VK; Markoulli M; Jeyakumar N; Hodge C; Sutton G; You J, 2019, 'In-vivo and in-vitro corneal epithelial and stromal thickness in Keratoconus', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vancouver, CANADA, Vol. 60, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, CANADA, 28 April 2019 - 02 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488628100317&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Stapleton F; Chao C; Jalbert I; Mandathara P; Kolanu S; Willcox M; Markoulli M; You JJ; Kim J; Lum E; Golebiowski B, 2016, 'Relationships between central corneal nerve parameters and tear neuropeptides', in Invest Ophthalmol Vis Sci, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Seattle, WA, Vol. 57, pp. E - abstract 2796, presented at ARVO Annual Meeting, Seattle, WA, 01 May 2016 - 05 May 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394210605041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2016
    Markoulli M; Lum E; You J; Duong C; Tolentino J; Kim J, 2016, 'CORNEAL NERVE MORPHOLOGY AND TEAR FILM SUBSTANCE P IN DIABETES', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Seattle, WA, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA, 01 May 2016 - 05 May 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394210602302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Stapleton F; Badarudin N; You JJ; Hampel U; Eden J; Raisin L; Williams J; Chao C; Golebiowski B, 2015, 'Determinants of ocular symptoms in postmenopaual women with dry eye', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Denver, CO, Vol. 56, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Denver, CO, 03 May 2015 - 07 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362891103255&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    You J; Wen L; Hodge C; Petsoglou C; Madigan M; Sutton G, 2015, 'A NEW WAY OF TISSUE CULTURING CORNEAL EPITHELIAL CELLS USING SILICONE GEL - APPLICATION ON KERATOCONUS CORNEAS', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY-BLACKWELL, Vol. 43, pp. 86 - 87, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363731000143&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2010
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Graham PH; Russell PJ; Walsh B; Willcox MD; Wasinger VC; Li Y, 2010, 'Identification of potential biomarkers for prostate cancer in tears and serum using proteomic approaches', presented at HUPO-9th Annual World Congress, Sydney, Australia, 19 September 2010 - 23 September 2010
    Conference Presentations | 2010
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Russell PJ; Walsh B; Willcox MD; Graham PH; Li Y, 2010, 'Using proteomic approaches to identify potential biomarkers for prostate cancer in tears and serum', presented at 3rd Annual World Cancer Congress, Singapore, 22 June 2010 - 25 June 2010
    Conference Presentations | 2010
    You J; Fitzgerald A; Schiller S; Cozzi PJ; Walsh B; Willcox MD; Wasinger VC; Li Y, 2010, 'Identification of potential biomarkers for prostate cancer in tears and serum using proteomic approaches', presented at The Inaugural Biomarker Discovery Conference, Port Stephens NSW Australia, 06 December 2010 - 10 December 2010
    Conference Papers | 2008
    Li Y; You J; Fitzgerald A; Cozzi PJ; Zhao Z; Russell PJ; Walsh B; Willcox MD, 2008, 'Identification of the potential biomarkers for prostate cancer from tears and serusing proteomic methods', in HUPO 2008 7th World Congress, HUPO 2008 7th World Congress, Amsterdam NL, presented at HUPO 2008 7th World Congress, Amsterdam NL, 16 August 2008 - 20 August 2008
    Conference Papers | 2008
    Li Y; Cozzi PJ; Zhao Z; Giannakis E; You J; Russell PJ; Walsh B; Willcox MD, 2008, 'SELDI-TOF-MS analysis of urine and tear samples to discover novel biomakersfor diagnosis and prognosis of prostate cancer', in AACR Annual Meeting 2008, AACR Annual Meeting 2008, San Diego, presented at AACR Annual Meeting 2008, San Diego, 12 April 2008 - 16 April 2008
    Conference Papers | 2008
    You J; Fitzgerald A; Cozzi PJ; Zhao Z; Russell PJ; Walsh B; Willcox MD; Li Y, 2008, 'Identification of the potential biomakers for prostate cancer from tears and sera using proteomic methods', in The 13th Annual Proteomics Symposium Erskine Mantra Resort, 13th Annual Proteomics Symposium Erskine Mantra Resort, Lorne , VIC, presented at 13th Annual Proteomics Symposium Erskine Mantra Resort, Lorne , VIC, 08 February 2008 - 10 February 2008
    Preprints |
    You J; Frazer H; Sayyar S; Chen Z; Liu X; Taylor A; Filippi B; Beirne S; Wise I; Hodge C; Wallace GG; Sutton G, Development of an <i> in-situ</i> Printing System with Human Platelet Lysate Based Bioink to Treat Corneal Perforation, http://dx.doi.org/10.2139/ssrn.3952393
    Preprints |
    You J; Frazer H; Sayyar S; Chen Z; Liu X; Taylor A; Filippi B; Beirne S; Wise I; Hodge C; Wallace G; Sutton G, Development of an in-situ printing system with human platelet lysate-based bio-adhesive to treat corneal perforation, http://dx.doi.org/10.1101/2021.09.13.460167