Dr Kang Liang
Senior Lecturer

Dr Kang Liang

Engineering
School of Chemical Engineering

Dr Kang Liang FRSC is a Scientia Associate Professor and group leader of Nano-Micro-Bio Systems. He received his Bachelor (Hon) and PhD degrees from the School of Chemical and Biomolecular Engineering at The University of Melbourne in 2010 and 2014, respectively. After conferral of his PhD, he joined CSIRO Manufacturing under the Office-of-the-Chief-Executive scheme in 2014 as a research fellow and then became a research scientist. In 2017, he joined the School of Chemical Engineering and the Graduate School of Biomedical Engineering at UNSW Sydney. He is an awardee of Victoria Fellowship in Physical Sciences in 2017. He is a board member of Australian Synchrotron Program Advisory Committee for SAXS/WAXS. He is a Fellow of the Royal Society of Chemistry. He is an NHMRC Career Development Fellow (2019-2022), and an ARC Future Fellow (2023-2027).

Google Scholar profile

  • PhD scholarships available! We encourage highly motivated PhD and MPhil students to join our group.
  • Postdoctoral researchers please do not hesitate to contact me about possible funding opportunities. 

 

Research interests                           

Interfacial Engineering of Nanostructured Materials

We are interested in interfacial engineering of nanostructured materials, in particular coordination based materials; understanding the material properties at a fundamental molecular level and relating nanostructure characteristics to bulk properties and material performance.

  • Adv. Mater. 2022, 10.1002/adma.202205674
  • J. Am. Chem. Soc. 2022, 10.1021/jacs.2c06471
  • Nano Today 2021, 40, 101256 
  • Small 2021, 17, 2100300
  • Adv. Funct. Mater. 2019, 1905321
  •  Chem, 2019, 5, 1597
  •  Mater. Today 2019, 28, 10
  •  Appl. Mater. Today 2018, 10, 93
  •  Acc. Chem. Res. 2017, 50, 1423
  •  Adv. Mater. 2016, 28, 7910
  •  Nat. Commun. 2015, 6, 7240

 

NanoBionics

We are interested in engineering nanobionics by interfacing nanomaterials with living organisms to introduce new or enhanced biological functions.

  • Adv. Funct Mater. 2021, 10.1002/adfm.202106787
  • Environ. Sci. Technol. 2020, 54, 11356
  • Science Advances 2020, 6, eaaz0330 
  • Adv. Funct. Mater. 2019, 1905321
  • Adv. Funct. Mater. 2019, 29, 1808900
  • Small 2018, 14, 1702958
  • Appl. Mater. Today 2018, 10, 93
  • Angew. Chem. Int. Ed. 2017, 56, 8510
  • Adv. Mater. 2016, 28, 7910

 

Biomimetics and Biomineralization

Biominerals, formed by living organisms through the self-organization of inorganic and organic building blocks, possess diverse and highly-organized hierarchical structures with superior material properties. Biomineralization has served as a source of inspiration for the development of materials with highly controllable and specialized properties. Our group first introduced the biomineralization of coordination materials, showing potential in catalysis, drug delivery, cytoprotection, and cell manipulation.

  • Chem. Eng. J. 2021, 426, 131861
  • Appl. Mater. Today 2018, 10, 93
  • Chem. Commun. 2017, 53, 1249
  • Adv. Mater. 2016, 28, 7910
  • Nat. Commun. 2015, 6, 7240
  • CrystEngComm 2016, 18, 4264
  • Chem. Commun. 2016, 52, 473
  • Adv. Mater. 2015, 27, 7293

 

Smart Nano-micro-bio Systems

We are interested in developing smart bioactive nanomaterials by interfacing bioactive compounds with functional materials, making it possible to perform desired tasks rapidly and efficiently when needed. These systems will have great potential for advanced energy and biotechnological applications.

  • Adv. Mater. 2022, 10.1002/adma.202205746
  • Angew Chem. Int. Ed. 2022, 10.1002/anie.202209747
  • Angew. Chem. Int. Ed. 2021, 60, 5421
  • Advanced Nanobiomed Research 2021, 1, 2000034
  • Chem. Commun. 2020, 56, 14837
  • Chem. Sci. 2019, 10, 7852
  • Mater. Today 2019, 28, 10
  • Adv. Funct. Mater. 2019, 201808900 
  • Chem, 2019, 5, 1597
  • Adv. Sci. 2018, 5, 1801155 
  • Nat. Commun. 2015, 6, 7240 

 

Publication highlights

  • J. Liang, B. Johannessen, Z. Wu, R. F. Webster, J. Yong, M. Y. B. Zulkifli, J. S. Harbort, Y. R. Cheok, H. Wen, Z. Ao, B. Kong, S. L.Y. Chang, J. Scott, K. Liang* "Regulating the Coordination Environment of Mesopore-confined Single Atoms from Metalloprotein-MOFs for Highly Efficient Biocatalysis" Adv. Mater. 2022, doi: 10.1002/adma.202205674.
  • J. Yong, A. S. Mellick, J. Whitelock, J. Wang, K. Liang* "A biomolecular toolbox for precision nanomotors" Adv. Mater. 2022, doi: 10.1002/adma.202205746.
  • J. Liang, M. Y. B. Zulkifli, J. Yong, Z. Du, Z. Ao, A. Rawal, J. Scott, J. Harmer, J. Wang, K. Liang* "Locking the Ultrasound-induced Active Conformation of Metalloenzymes in Metal-organic Frameworks" J. Am. Chem. Soc. 2022, doi: 10.1021/jacs.2c06471.
  • Z. Guo, Y. Wu, Z. Xie, J. Shao, J. Liu, Y. Yao, J. Wang, Y. Shen*, J. J. Gooding*, K. Liang* "Self-Propelled Initiative Collision at Microelectrodes with Vertically Mobile Micromotors" Angew. Chem. Int. Ed. 2022, 10.1002/anie.202209747.
  • J. Liu,J. Xue,L. Fu,J. Xu, M. S. Lord, K. Liang* "Genetically Encoded Synthetic Beta Cells for Insulin Biosynthesis and Release under Hyperglycemic Conditions" Adv. Funct. Mater. 202210.1002/adfm.202111271.
  • J. Liang, K. Liang* "Nano-bio-interface engineering of metal-organic frameworks" Nano Today 2021, 40, 101256.
  • J. Liang, M. Yu, J. Liu, Z. Yu, K. Liang,* D.-W. Wang* "Energy Storing Plant Stem with Cytocompatibility for Supercapacitor Electrode" Adv. Funct. Mater. 202110.1002/adfm.202106787
  • J. Liang, S. Gao, J. Liu, M. Y.B. Zulkifli, J. Xu, J. Scott, V. Chen, J. Shi, A. Rawal, K. Liang* "Hierarchically Porous Biocatalytic MOF Microreactor as a Versatile Platform towards Enhanced Multienzyme and Cofactor‐Dependent Biocatalysis" Angew. Chem. Int. Ed. 2021 doi:10.1002/anie.202014002
  • J. Liang, M.Y.B. Zulkifli, S. Choy, Y. Li, M. Gao, B. Kong, J. Yun, K. Liang* "Metal-Organic Framework-Plant Nanobiohybrids as Living Sensors for On-Site Environmental Pollutants Detection" Environ. Sci. Technol. 2020, doi: 10.1021/acs.est.0c04688
  • J. Liang, K. Liang* "Biocatalytic Metal-Organic Frameworks: Prospects Beyond Bioprotective Porous Matrices" Adv. Funct. Mater. 2020, doi: 10.1002/adfm.202001648.
  • Z. Guo, J. J. Richardson, B. Kong, K. Liang* "Nanobiohybrids: Materials approaches for bioaugmentation" Sci. Adv. 2020, 6, eaaz0330
  • J. Liu, Z. Guo, K. Liang* "Biocatalytic metal-organic framework-based artificial cells" Adv. Funct. Mater. 2019, 1905321.
  • J. Liang, F, Mazur, C. Tang, X. Ning,* R. Chandrawati,* K. Liang* "Peptide-Induced Super-Assembly of Biocatalytic Metal-Organic Frameworks for Programmed Enzyme Cascade" Chem. Sci. 2019, 10, 7852-7858
  • Z. Guo, T. Wang, A. Rawal, J. Hou, Z. Cao, H. Zhang, J. Xu, Z Gu,* V. Chen, K. Liang* "Biocatalytic self-propelled submarine-like microparticles with pH-triggered buoyancy control for directional vertical motion" Mater. Today 2019, 28, 10-16.
  • S. Gao, J. Hou,* Z. Deng, T. Wang, S. Beyer, A. Guilherme Buzanich, J. J. Richardson, A. Rawal, R. Seidel, M. Y. Zulkifli, W. Li, T. D. Bennett,  A. K. Cheetham, K. Liang,* V Chen "Improving the acidic stability of zeolitic imidazolate frameworks by bio-functional molecules" Chem 2019, 5, 1597-1608.
  • S. Gao, J. Hou, J. Zeng, J. J. Richardson, Z. Gu, X. Gao, D. Li, M. Gao, D.-W. Wang, P. Chen, V. Chen,* D. Zhao, B. Kong,* K. Liang* “Super-assembled Biocatalytic Porous Framework Micromotors with Reversible and Sensitive pH-Speed Regulation at Ultralow Physiological H2O2 Concentration” Adv. Funct. Mater. 2019, 29, 1808900.
  • Y. Chu, J. Hou, C. Boyer, J. J. Richardson,* K. Liang,* J. Xu* "Biomimetic synthesis of coordination network materials: Recent advances in MOFs and MPNs" Appl. Mater. Today 2018, 10, 93-105.
  • J. J. Richardson,* K. Liang* ”Nano‐Biohybrids: In Vivo Synthesis of Metal–Organic Frameworks inside Living Plants“ Small 2018, 141702958.

 

Phone
+61 2 93854337
Location
Science and Engineering Building (E8), UNSW Sydney, Kensington
  • Journal articles | 2022
    Chen K; Yong J; Zauner R; Wally V; Whitelock J; Sajinovic M; Kopecki Z; Liang K; Scott KF; Mellick AS, 2022, 'Chondroitin Sulfate Proteoglycan 4 as a Marker for Aggressive Squamous Cell Carcinoma.', Cancers (Basel), vol. 14, http://dx.doi.org/10.3390/cancers14225564
    Journal articles | 2022
    Liang J; Zeng J; Huang X; Zhu T; Gong Y; Dong C; Wang X; Zhao L; Xie L; Liang K; Tan Q; Cui Y; Kong B; Hui W, 2022, 'Super-assembly of integrated gold magnetic assay with loop-mediated isothermal amplification for point-of-care testing', Nano Research, http://dx.doi.org/10.1007/s12274-022-4692-9
    Journal articles | 2022
    Xie L; Liu T; He Y; Zeng J; Zhang W; Liang Q; Huang Z; Tang J; Liang K; Jiang L; Terasaki O; Zhao D; Kong B, 2022, 'Kinetics-Regulated Interfacial Selective Superassembly of Asymmetric Smart Nanovehicles with Tailored Topological Hollow Architectures', Angewandte Chemie - International Edition, vol. 61, http://dx.doi.org/10.1002/anie.202200240
    Journal articles | 2022
    Xing C; Deng J; Fu W; Li J; Xu L; Sun R; Wang D; Li C; Liang K; Gao M; Kong B, 2022, 'Interfacially Super-Assembled Benzimidazole Derivative-Based Mesoporous Silica Nanoprobe for Sensitive Copper (II) Detection and Biosensing in Living Cells', Chemistry - A European Journal, vol. 28, pp. e202103642, http://dx.doi.org/10.1002/chem.202103642
    Journal articles | 2022
    Yan M; Ma D; Qiu B; Liu T; Xie L; Zeng J; Liang K; Xin H; Lian Z; Jiang L; Kong B, 2022, 'Superassembled Hierarchical Asymmetric Magnetic Mesoporous Nanorobots Driven by Smart Confined Catalytic Degradation', Chemistry - A European Journal, vol. 28, http://dx.doi.org/10.1002/chem.202200307
    Journal articles | 2022
    Zhou Y; Mazur F; Liang K; Chandrawati R, 2022, 'Sensitivity and Selectivity Analysis of Fluorescent Probes for Hydrogen Sulfide Detection', Chemistry - An Asian Journal, vol. 17, pp. e202101399, http://dx.doi.org/10.1002/asia.202101399
    Journal articles | 2021
    Liu J; Guo Z; Li Y; Liang J; Xue J; Xu J; Whitelock JM; Xie L; Kong B; Liang K, 2021, 'pH-Gated Activation of Gene Transcription and Translation in Biocatalytic Metal-Organic Framework Artificial Cells', ADVANCED NANOBIOMED RESEARCH, vol. 1, http://dx.doi.org/10.1002/anbr.202000034
    Journal articles | 2018
    Cao Z; Zhang L; Liang K; Cheong S; Boyer C; Gooding JJ; Chen Y; Gu Z, 2018, 'Biodegradable 2D Fe–Al Hydroxide for Nanocatalytic Tumor-Dynamic Therapy with Tumor Specificity', Advanced Science, vol. 5, http://dx.doi.org/10.1002/advs.201801155

Current active grants

  • ARC Discovery Project 2023-2025 (DP230101312)
  • ARC Future Fellowship 2022-2026 (FT220100479)
  • NBCF Investigator Initiated Research Scheme 2022-2025 (IIRS-22-104)
  • ARC Discovery Project 2021-2023 (DP210100422)
  • NHMRC Career Development Fellowship 2019-2022 (GNT1163786)
  • ARC Linkage Project 2019-2022 (LP190100029)
  • ARC Discovery Project 2019-2021 (DP190101008)
  • UNSW-CAS Bridging Grant 2019-2022
  • UNSW Scientia Fellowship 2021-2025

 

Past grants

  • Research Infrastructure Scheme (RIS) Network lab 2019-2021
  • UNSW Scientia Fellowship 2017-2021
  • CSIRO OCE Fellowship 2014-2017
  • Science and Industry Endowment Fund 2015 

  • ARC Future Fellowship, 2022

  • Second runner up of the ES&T Best Paper Award for Best Environmental Technology Article in 2020, 2021

  • Fellow of the Royal Society of Chemistry (FRSC), 2021

  • Research Excellence Award, UNSW, 2018

  • Career Development Fellowship, NHMRC, 2019

  • Scientia Fellowship, UNSW, 2017

  • Vicoria Fellowship, VESKI, 2017

  • Performance Cash Award, CSIRO, 2015

  • Australian Nanotechnology Network (ANN) award, 2015

  • 65th Lindau Nobel Laureate Meeting nominee, Executive Secretariat Lindau Nobel Laureate Meetings, Lindau Germany, 2015