Dr Ki Wook   Kim
Lecturer

Dr Ki Wook Kim

Medicine & Health
Discipline of Paediatrics

Dr Ki Wook Kim is a Juvenile Diabetes Research Foundation (JDRF) International Postdoctoral Research Fellow in the School of Women's and Children's Health at the University of New South Wales, based at the Prince of Wales Hospital. He completed both his Honours and PhD in Molecular Biology and Genetics at the University of Sydney, for which he investigated the roles and interactions of various microRNAs and RNA silencing component proteins in the model plant, Arabidopsis thaliana. During his PhD, he accumulated extensive training in molecular research and advanced microscopy at various leading institutions including the Victor Chang Cardiac Research Institute, CSIRO and the John Curtin School of Medical Research at ANU. He has recently joined the VRL to commence his first postdoctoral position, pursuing his long-standing passion for medical research.

Project

Viral triggers of islet autoimmunity and type 1 diabetes.

Research Interests

Type 1 diabetes is an autoimmune disease that affects approximately 140 000 children and adults in Australia and over 16 million people worldwide. It is thought to arise from the complex interplay between genetic predisposition and exposure to various environmental agents. For decades, the involvement of Enteroviruses in the pathogenesis of this disease has been strongly debated.

Dr Kim is interested in further elucidating the molecular events initiated by Enteroviruses that might contribute to the onset of type 1 diabetes, especially those involving the dysregulation of microRNAs. He is also interested in the application of Next-Generation Sequencing technologies to investigate changes in the transcriptome and virome of human pancreatic islets prior to or following the development of type 1 diabetes. 

Qualifications

B.Sci (Molecular Biology & Genetics)(Hons I) USyd, PhD Usyd.

Location
Virology Research Laboratory, Clinical Sciences Building Level 3, Prince of Wales Hospital.

Publications

  • Book Chapters | 2011
    Dr Ki Wook Kim
    Kim KW; Eamens AL; Waterhouse PM, 2011, 'RNA Processing Activities of the Arabidopsis Argonaute Protein Family', in Grabowski P (ed.), RNA Processing, InTech Open, http://dx.doi.org/10.5772/22686
  • Journal articles | 2021
    Dr Ki Wook Kim
    Isaacs SR; Foskett DB; Maxwell AJ; Ward EJ; Faulkner CL; Luo JYX; Rawlinson WD; Craig ME; Kim KW, 2021, 'Viruses and type 1 diabetes: From enteroviruses to the virome', Microorganisms, vol. 9, pp. 1519 - 1519, http://dx.doi.org/10.3390/microorganisms9071519
    Journal articles | 2021
    Dr Ki Wook Kim
    Kim KW; Deveson IW; Pang CNI; Yeang M; Naing Z; Adikari T; Hammond JM; Stevanovski I; Beukers AG; Verich A; Yin S; McFarlane D; Wilkins MR; Stelzer-Braid S; Bull RA; Craig ME; van Hal SJ; Rawlinson WD, 2021, 'Respiratory viral co-infections among SARS-CoV-2 cases confirmed by virome capture sequencing', Scientific Reports, vol. 11, pp. 3934, http://dx.doi.org/10.1038/s41598-021-83642-x
    Journal articles | 2020
    Dr Ki Wook Kim
    Faulkner CL; Luo YX; Isaacs S; Rawlinson WD; Craig ME; Kim KW, 2020, 'The virome in early life and childhood and development of islet autoimmunity and type 1 diabetes: A systematic review and meta-analysis of observational studies', Reviews in Medical Virology, http://dx.doi.org/10.1002/rmv.2209
    Journal articles | 2020
    Dr Ki Wook Kim
    Bull RA; Adikari TN; Ferguson JM; Hammond JM; Stevanovski I; Beukers AG; Naing Z; Yeang M; Verich A; Gamaarachchi H; Kim KW; Luciani F; Stelzer-Braid S; Eden JS; Rawlinson WD; van Hal SJ; Deveson IW, 2020, 'Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis', Nature Communications, vol. 11, pp. 6272, http://dx.doi.org/10.1038/s41467-020-20075-6
    Journal articles | 2020
    Dr Ki Wook Kim
    Kim KW; Allen DW; Briese T; Couper JJ; Barry SC; Colman PG; Cotterill AM; Davis EA; Giles LC; Harrison LC; Harris M; Haynes A; Horton JL; Isaacs SR; Jain K; Lipkin WI; McGorm K; Morahan G; Morbey C; Pang ICN; Papenfuss AT; Penno MAS; Sinnott RO; Soldatos G; Thomson RL; Vuillermin P; Wentworth JM; Wilkins MR; Rawlinson WD; Craig ME, 2020, 'Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes', Pediatric Diabetes, vol. 21, pp. 271 - 279, http://dx.doi.org/10.1111/pedi.12952
    Journal articles | 2019
    Dr Ki Wook Kim
    Kim KW; Allen DW; Briese T; Couper JJ; Barry SC; Colman PG; Cotterill AM; Davis EA; Giles LC; Harrison LC; Harris M; Haynes A; Horton JL; Isaacs SR; Jain K; Lipkin WI; Morahan G; Morbey C; Pang ICN; Papenfuss AT; Penno MAS; Sinnott RO; Soldatos G; Thomson RL; Vuillermin PJ; Wentworth JM; Wilkins MR; Rawlinson WD; Craig ME, 2019, 'Distinct gut virome profile of pregnant women with type 1 diabetes in the ENDIA study', Open Forum Infectious Diseases, vol. 6, http://dx.doi.org/10.1093/ofid/ofz025
    Journal articles | 2019
    Dr Ki Wook Kim
    Craig ME; Kim KW; Isaacs SR; Penno MA; Hamilton-Williams EE; Couper JJ; Rawlinson WD, 2019, 'Early-life factors contributing to type 1 diabetes', Diabetologia, vol. 62, pp. 1823 - 1834, http://dx.doi.org/10.1007/s00125-019-4942-x
    Journal articles | 2019
    Dr Ki Wook Kim
    Kim KW; Horton JL; Pang CNI; Jain K; Leung P; Isaacs SR; Bull RA; Luciani F; Wilkins MR; Catteau J; Lipkin WI; Rawlinson WD; Briese T; Craig ME, 2019, 'Higher abundance of enterovirus A species in the gut of children with islet autoimmunity', Scientific Reports, vol. 9, pp. 1749, http://dx.doi.org/10.1038/s41598-018-38368-8
    Journal articles | 2018
    Dr Ki Wook Kim
    Isaacs SR; Kim KW; Cheng JX; Bull RA; Stelzer-Braid S; Luciani F; Rawlinson WD; Craig ME, 2018, 'Amplification and next generation sequencing of near full-length human enteroviruses for identification and characterisation from clinical samples', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-30322-y
    Journal articles | 2018
    Dr Ki Wook Kim
    Allen DW; Kim KW; Rawlinson WD; Craig ME, 2018, 'Maternal virus infections in pregnancy and type 1 diabetes in their offspring: Systematic review and meta-analysis of observational studies', Reviews in Medical Virology, vol. 28, http://dx.doi.org/10.1002/rmv.1974
    Journal articles | 2016
    Dr Ki Wook Kim
    Isaacs SR; Wang J; Kim KW; Yin C; Zhou L; Mi QS; Craig ME, 2016, 'MicroRNAs in Type 1 Diabetes: Complex Interregulation of the Immune System, β Cell Function and Viral Infections', Current Diabetes Reports, vol. 16, http://dx.doi.org/10.1007/s11892-016-0819-2
    Journal articles | 2016
    Dr Ki Wook Kim
    Kim KW; Ho A; Alshabee-Akil A; Hardikar AA; Kay TWH; Rawlinson WD; Craig ME, 2016, 'Coxsackievirus B5 infection induces dysregulation of microRNAs predicted to target known type 1 diabetes risk genes in human pancreatic islets', Diabetes, vol. 65, pp. 996 - 1003, http://dx.doi.org/10.2337/db15-0956
    Journal articles | 2012
    Dr Ki Wook Kim
    Eamens AL; Kim KW; Waterhouse PM, 2012, 'DRB2, DRB3 and DRB5 function in a non-canonical microRNA pathway in Arabidopsis thaliana', Plant Signaling and Behavior, vol. 7, pp. 1224 - 1229, http://dx.doi.org/10.4161/psb.21518
    Journal articles | 2012
    Dr Ki Wook Kim
    Eamens AL; Kim KW; Curtin SJ; Waterhouse PM, 2012, 'DRB2 is required for microRNA biogenesis in Arabidopsis thaliana', PLoS ONE, vol. 7, pp. e35933 - e35933, http://dx.doi.org/10.1371/journal.pone.0035933
    Journal articles |
    Dr Ki Wook Kim
    Isaacs SR; Foskett DB; Maxwell AJ; Ward EJ; Faulkner CL; Luo JYX; Rawlinson WD; Craig ME; Kim KW, 'Viruses and Type 1 Diabetes: From Enteroviruses to the Virome', , http://dx.doi.org/10.20944/preprints202106.0574.v1
    Journal articles |
    Dr Ki Wook Kim
    Kim KW; Deveson IW; Pang CNI; Yeang M; Naing Z; Adikari T; Hammond JM; Stevanovski I; Beukers AG; Verich A; Yin S; McFarlane D; Wilkins MR; Stelzer-Braid S; Bull RA; Craig ME; Hal SJV; Rawlinson WD, 'Respiratory viral co-infections among SARS-CoV-2 cases confirmed by virome capture sequencing', , http://dx.doi.org/10.21203/rs.3.rs-105996/v1
  • Conference Papers | 2017
    Dr Ki Wook Kim
    Horton JL; Kim KW; Pang CN; Jain K; Leung P; Isaacs SR; Bull RA; Luciani F; Wilkins MR; Lipkin WI; Rawlinson WD; Briese T; Craig ME, 2017, 'Virome-Capture Sequencing of the Gut and Plasma Virome in Children with Islet Autoimmunity', in DIABETES, AMER DIABETES ASSOC, pp. LB51 - LB52, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000463087200190&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Dr Ki Wook Kim
    Kim KW; Allen DW; Briese T; Pang CN; Jain K; Horton JL; Isaacs SR; Wilkins MR; Couper J; Penno MAS; Harrison LC; Morahan G; Harris M; Cotterill AM; Morbey C; Barry SC; Haynes A; Davis E; Colman P; Giles L; Dodd J; Wentworth J; Sinnott R; Papenfuss TA; Vuillermin P; Lipkin WI; Rawlinson WD; Craig ME, 2017, 'Gut Virome Dynamics during Pregnancy in Mothers with Type 1 Diabetes', in DIABETES, AMER DIABETES ASSOC, pp. LB51 - LB51, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000463087200189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Awards

Grants

Media